Thomas Maier
Thomas Maier, Leipzig DE
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20100248298 | MASS SPECTROMETRIC IDENTIFICATION OF MICROORGANISMS IN COMPLEX SAMPLES - Microorganisms are identified as present in a complex sample or mixed culture by acquiring a mass spectrum of the sample and comparing it to combination spectra, each of which is formed by combining at least two reference mass spectra of known microorganisms. Microorganisms corresponding to the reference spectra used to form the combination spectrum are identified as present in the sample if that combination spectrum exhibits a better match with the sample mass spectrum than any one of reference mass spectra used to form that combination spectrum. It is also possible to identify microorganisms by forming a difference spectrum by subtracting a reference mass spectrum from the sample mass spectrum and comparing the difference spectrum to the reference mass spectra. | 09-30-2010 |
20110012016 | SPECTROPHOTOMETRIC IDENTIFICATION OF MICROBE SUBSPECIES - A dual-stage method is provided for identifying a microbe by, for example, its species or its subspecies. The method includes measuring a mass spectrum of the microbe using a mass spectrometer, calculating indicators for similarities between reference mass spectra in a library and the measured mass spectrum, selecting a group of reference mass spectra similar to the measured mass spectrum, determining a distinguishing weight for each mass signal of the reference mass spectra in the group, where the distinguishing weights emphasize differences between the reference mass spectra in the group, and calculating indicators for similarities between the reference mass spectra in the group and the measured mass spectrum as a function of the distinguishing weights. | 01-20-2011 |
20120115182 | MASS SPECTROMETRIC DIAGNOSIS OF SEPTICEMIA - The invention mainly relates to the mass spectrometric identification of pathogens in blood cultures from blood-stream infections (septicemia). The invention provides a method with which microbial pathogens can be separated in purified form from blood after a relatively brief cultivation in a blood culture flask, without any interfering human proteins or any residual fractions of blood particles such as erythrocytes and leukocytes, and can be directly identified by mass spectrometric measurement of their protein profiles. The method is based on the use of relatively strong tensides to destroy the blood particles by dissolving the weak cell membranes and most of the internal structures of the blood particles; in spite of the fact that tensides are regarded as strong ionization inhibitors in MALDI and other ionization processes required for mass spectrometric measurements. This method allows unknown pathogens to be obtained in their pure form by centrifuging or filtration and to be identified on the taxonomic level of species or subspecies. Problems with DNA from high levels of leukocytes can be resolved by special measures. After sufficient cultivation, the identification in a mass spectrometric laboratory takes only half an hour. | 05-10-2012 |
20140051117 | MASS SPECTROMETRIC DIAGNOSIS OF SEPTICEMIA - The invention mainly relates to the mass spectrometric identification of pathogens in blood cultures from bloodstream infections (septicemia). The invention provides a method with which microbial pathogens can be separated in purified form from blood after a relatively brief cultivation in a blood culture flask, without any interfering human proteins or any residual fractions of blood particles such as erythrocytes and leukocytes, and can be directly identified by mass spectrometric measurement of their protein profiles. The method is based on the use of relatively strong tensides to destroy the blood particles by dissolving the weak cell membranes and most of the internal structures of the blood particles; in spite of the fact that tensides are regarded as strong ionization inhibitors in MALDI and other ionization processes required for mass spectrometric measurements. This method allows unknown pathogens to be obtained in their pure form by centrifuging or filtration and to be identified on the taxonomic level of species or subspecies. Problems with DNA from high levels of leukocytes can be resolved by special measures. After sufficient cultivation, the identification in a mass spectrometric laboratory takes only half an hour. | 02-20-2014 |
Thomas Maier, Aschaffenburg DE
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20110005328 | BI-AXIAL ELECTROMAGNETIC ACTUATOR - A biaxial electromagnetic actuator for a materials testing apparatus comprises a first electromagnetic actuator for imparting a linear force to an output shaft and a second, direct drive electromagnetic actuator for imparting a rotational force to the shaft. The shaft is mounted in two combination bearings which permit the shaft to move axially and rotationally. One of the bearings is located within a hollow cylindrical member which constitutes the armature of the direct drive actuator in order to provide a compact and symmetrical arrangement. | 01-13-2011 |
Thomas Maier, Konstanz DE
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20100261721 | Novel Sulphonylpyrroles - Compounds of a certain formula (I), in which R1, R2, R3, R4, R5, R6 and R7 have the meanings indicated in the description, are novel effective HDAC inhibitors. | 10-14-2010 |
20100261761 | Novel Sulfonylpyrroles - Compounds of a certain formula (I), in which R1, R2, R3, R4, R5, R6 and R7 have the meanings indicated in the description, are novel effective HDAC inhibitors. | 10-14-2010 |
20130079347 | NOVEL SULFONYLPYRROLES - Compounds of a certain formula (I), in which R1, R2, R3, R4, R5, R6 and R7 have the meanings indicated in the description, are novel effective HDAC inhibitors. | 03-28-2013 |
Thomas Maier, Hofheim DE
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20100234227 | MICROEMULSION CONCENTRATES - The present invention relates to a microemulsion concentrate, comprising | 09-16-2010 |
Thomas Maier, Albstadt DE
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20090064475 | Transport cart for needle boards - A transport cart ( | 03-12-2009 |
20100218352 | Transport Carriage for Needle Boards - The transport carriage ( | 09-02-2010 |
Thomas Maier, Lauffen DE
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20100170223 | CONTROL AND/OR DRIVE DEVICE FOR A FLYING BODY - Control and/or drive device for a flying body for ejecting hot gas streams of a combusted fuel combination of at least a first and second component. Device includes a first hollow chamber body structured and arranged to contain first component, a second hollow chamber body structured and arranged to contain second component, a controllable fuel valve arranged between first hollow chamber body and second hollow chamber body to control feed of first component to second hollow chamber body, and a plurality of outlets structured and arranged to eject respective hot gas streams for influencing a flight path of flying body. Second hollow chamber body is formed as a combustion chamber for combusting the at least first and second components within second hollow chamber body to generate respective hot gas streams, and plurality of outlets are connected to the second hollow chamber body. | 07-08-2010 |
20140061517 | Device for Regulating the Pressure and/or Mass Flow for a Space Propulsion System - A device for regulating pressure and/or mass flow of a gaseous or liquid fluid conveyed through a line in a space propulsion system includes a first, piezoelectrically actuatable regulating valve and at least two second, magnetically actuatable regulating valves. The regulating valves are connected to each other and to a line input in such a way that in a nominal mode the pressure and the mass flow of the fluid can be set by the first regulating valve, and a connection or isolation of the first regulating valve with or from the line input can be produced by the second regulating valves. In an emergency mode the pressure and the mass flow of the fluid can be set by the second regulating valves. | 03-06-2014 |
20140217313 | VALVE FOR OPENING A FLUID LINE - A valve for one-time opening a fluid line for venting a technical system includes an inlet for connecting to the fluid line, an outlet, and a controllable closure arranged between the inlet and the outlet. In the non-activated state the controllable closure closes a passage between the inlet and the outlet. The closure includes a material that changes its phase state in dependence on a control parameter, whereby the passage is irreversibly opened in the activated state. | 08-07-2014 |
20150028234 | Device for Opening or Closing a Seal Set of a Valve - A device for opening or closing a seal seat of a valve arranged in a pipe for liquid or gaseous media includes a one-time only activation of the valve using a shape memory actuator. The shape memory actuator changes its external shape abruptly when a transformation temperature is reached that is dependent upon its alloy composition. The transformation temperature can be generated by a controllable electrical heating device of the device. | 01-29-2015 |
20150028238 | Valve Assembly for Switching and/or Regulating a Medium Flow of an Aerospace Engine and Aerospace Engine - A valve assembly for switching and/or regulating a medium flow of an aerospace engine includes a drive, a valve and a flexible separator element. The drive includes one or more electrically actuatable actuators, which change their length in the direction of a longitudinal axis of the valve assembly when a control voltage is applied to the actuators. The valve includes a valve piston, which can be moved back and forth along the longitudinal axis by the drive and which has a valve member. The flexible separator element delimits a working space of the valve from the drive, as a result of which the medium, which flows through the valve or is present in the working space, is hermetically separated from the drive. | 01-29-2015 |
Thomas Maier, Dachau DE
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20090298135 | Method for fermentative production of L-methionine - A microorganism strain suitable for fermentative production of L-methionine and preparable from a starting strain, which comprises increased activity of a yjeH gene product or of a gene product of a yjeH homolog, compared to the starting strain. | 12-03-2009 |
Thomas Maier, Aalen DE
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20080295349 | Coordinate Measuring Machine and Method for Operating a Coordinate Measuring Machine - In a method for operating a coordinate measuring machine and to a coordinate measuring machine, a coordinate measuring device, of the coordinate measuring machine is moved in at least one direction while being driven by an electric motor. An electrical drive current which flows through the electric motor for moving the electric motor and, move the coordinate measuring device is measured. A limit value for the electrical drive current is determined on the basis of a desired speed and/or on the basis of a desired acceleration with which the electric motor or the coordinate measuring device is intended to move. If the electrical drive current reaches the limit value determined and/or if the electrical drive current exceeds the limit value determined, the coordinate measuring device is changed to a predefined state, by virtue of the computer or the microcontroller switching off one of the switches disposed in the current path. | 12-04-2008 |
20090026995 | Reliable Monitoring of the Speed in Coordinate Measuring Appliances - In a method for reliably monitoring the speed of a moveable coordinate measuring device, a first value of the speed is calculated from measured values of the coordinate measurement system. The measured values contain information on positions of the coordinate measuring device. The measured values are further used to determine the coordinates of a measurement object. A second value of the speed is ascertained from measurement signals of at least one additional movement sensor. The measurement signals can also be used for controlling a drive device of the coordinate measuring device. A fault signal can be generated if the first value and/or the second value deviate from one another, from a predetermined value and/or a limit value according to a predefined criterion. | 01-29-2009 |
Thomas Maier, Neunburg V. Wald DE
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20080203952 | Electronic Control Unit For Controlling External Half-Bridge Power Output Stages and an Electric Motor Operated Drive With Electronic Control Unit - In order to control an electromotive drive, a control unit has control modules for controlling half-bridge end power stages. Two of the control modules are pre-configured for alternatively controlling a commutator motor or a brushless electric motor via two half-bridge end power stages. A third control module can be subsequently configured to control a third half-bridge end power stage or two individual switching elements. An electromotive drive ideally can be configured with the stated control unit. | 08-28-2008 |
20110241582 | CONTROL DEVICE FOR A MOTOR AND METHOD FOR CONTROLLING SAID MOTOR - A control device is for a motor, especially a brushless DC motor. The control device contains a bridge circuit for generating a rotating field for the motor and a sensor system for detecting a position of a rotor of the motor, a control signal for the bridge circuit being derivable from the signal representing the rotor position. The sensor system includes an absolute value transmitter which detects the absolute position of the rotor and which is configured to derive at least one incremental signal from the absolute position and to make it directly available to a control component for controlling the bridge circuit for commuting the motor. | 10-06-2011 |
Thomas Maier US
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20110166140 | NOVEL SULPHONYLPYRROLES - Compounds of a certain formula (I), in which R1, R2, R3, R4, R5, R6 and R7 have the meanings indicated in the description, are novel effective HDAC inhibitors. | 07-07-2011 |
Thomas Maier, Wien AT
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20110304005 | RESONATOR ELEMENT AND RESONATOR PIXEL FOR MICROBOLOMETER SENSOR - A resonator element for the absorption and/or conversion of electromagnetic waves having a predefined wavelength, in particular infrared radiation having a wavelength of 2 μm to 200 μm, into heat, has a three-layer structure formed of a first metal layer, a second metal layer and a dielectric layer interposed between the two metal layers. The maximum lateral dimension of the layers is in the range between one quarter and a half of the predefined wavelength. | 12-15-2011 |
Thomas Maier, Lilienthal DE
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20120152041 | SAMPLE PREPARATION FOR IONIZATION WITH MATRIX-ASSISTED LASER DESORPTION - A simplified sample preparation on a sample support for ionization with laser desorption (MALDI or LDCI, for example) includes depositing an analyte material onto a deposition site, providing a sample site which is intended as the substrate for a matrix crystal layer at a distance from the deposition site, and establishing a liquid communication between the deposition site and the sample site. A device for the preparation of samples for ionization with matrix-assisted laser desorption, and a sample support for use with the inventive method are also disclosed. | 06-21-2012 |
20130309712 | MASS SPECTROMETRIC IDENTIFICATION OF HYPHAL FUNGI - A method is provided for identifying a hyphal fungus in a sample by similarity comparisons between a mass spectrum of the fungus and reference spectra. The method includes growing fresh hyphae without any adhering contact to surfaces as to form a mycelium with undifferentiated hyphae cells. A sample is prepared from the hyphae cells, and a mass spectrum is acquired of the hyphae cell sample. The mass spectrum is matched with at least one reference spectrum. | 11-21-2013 |
Thomas Maier, Dietingen DE
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20130043103 | SORTING DEVICE - A sorting device having at least one control unit for sorting mixtures of individual elements in sorting units according to at least one characterizing feature of the individual elements and having at least one conveyor belt. The sorting device comprises at least one buffer unit having at least two displaceable storage elements for intermediate storage of individual elements. | 02-21-2013 |
Thomas Maier, Frankfurt Am Main DE
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20130131034 | DERIVATIVES OF AMINOINDANES, THEIR PREPARATION AND THEIR APPLICATION IN THERAPEUTICS - The instant invention relates to derivatives of formula (I) | 05-23-2013 |
20140099333 | PYRROLIDINONE DERIVATIVES AS GPR119 MODULATORS FOR THE TREATMENT OF DIABETES, OBESITY, DYSLIPIDEMIA AND RELATED DISORDERS - The present invention relates to pyrrolidinone derivatives. The pyrrolidinone derivatives are GPR119 modulators and useful for the prevention and/or treatment of diabetes, obesity, dyslipidemia and related disorders. The invention furthermore relates to the use of pyrrolidinone derivatives as active ingredients in pharmaceuticals, and pharmaceutical compositions comprising them. | 04-10-2014 |
Thomas Maier, Garching A.d. Alz DE
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20140083993 | PRINTED CIRCUIT BOARD FOR A DOMESTIC APPLIANCE, DOMESTIC APPLIANCE, AND A METHOD FOR OPERATING A DOMESTIC APPLIANCE - A printed circuit board for a domestic appliance includes at least one conductive path which is provided on at least one of two sides of the printed board and adapted for supply with a load current. The printed circuit board has at least one magnetic field sensor which is configured and disposed to read a magnetic field that can be generated by the load current. The load current flowing through the at least one conductive path of the printed circuit board can be detected by contactless reading of the magnetic field generated by the load current through the at least one conductive path. | 03-27-2014 |
Thomas Maier, Tualatin, OR US
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20140071808 | CALL FLOW DIAGNOSTIC SYSTEM FOR HETEROGENEOUS NETWORKS - A call flow diagnostic system and/or methods for monitoring, diagnosing and updating a communication network for high bandwidth, real time, feature-rich voice/video communications. An interface component is operatively coupled to the communication network. A monitoring and alert component coupled to the network devices monitors in real time transmission and device status, and the condition, state, routing, transmission, transformation settings, and packet or call routing settings of the network devices. The component collects, debugs and traces information from the network devices. A graphical user interface is coupled to the monitoring and alert component and displays information to an operator about network device status, diagnostics results, alerts, instructions in real time. | 03-13-2014 |
Thomas Maier, Kaufbeuren DE
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20140175838 | Wheel Fender | 06-26-2014 |