Patent application number | Description | Published |
20140213622 | PHARMACEUTICAL COMPOSITIONS COMPRISING AN AROMATSE INHIBITORS - The invention relates to low-dose pharmaceutical compositions comprising the aromatase inhibitor 4,4′[fluoro-(1-H-1,2,4-triazol-1-yl)methylene]bisbenzonitrile, as the active ingredient in a suitable carrier. The present invention also relates to a process for their preparation and to their use as therapeutic agents. | 07-31-2014 |
20140309267 | USE OF AN AROMATASE INHIBITOR FOR THE TREATMENT OF HYPOGONADISM AND RELATED DISEASES - The aromatase inhibitor 4,4′-[fluoro-(1-H-1,2,4-triazol-1-yl)methylene]bisbenzonitrile increases testosterone levels and treats hypogonadism and related diseases. A particular dosing regimen is disclosed as well as pharmaceutical compositions comprising said of 4,4′-[fluoro-(1-H-1,2,4-triazol-1-yl)methylene]bisbenzonitrile, optionally in combination with other active ingredients and kits comprising the pharmaceutical compositions. | 10-16-2014 |
20140328859 | ANTIBODIES AND METHODS FOR WNT PATHWAY-RELATED DISEASES - The transmembrane E3 ubiquitin ligases ZNRF3 and RNF43 are negative regulators of β-catenin and the Wnt signaling pathway in eukaryotic cells. The activity of ZNRF3 can be modulated by antibody binding to its extracellular domain, thus causing an increase in Wnt signaling. The ZNRF3 antagonizing antibodies can be used to treat diseases with low Wnt signaling, such as short bowel syndrome, osteoporosis, diabetes, neurodegenerative diseases, and mucositis. In addition, the antagonizing antibodies of the invention can be used to enhance Wnt signaling for tissue repair and wound healing. | 11-06-2014 |
Patent application number | Description | Published |
20100146566 | Method of Data Management for Efficiently Storing and Retrieving Data to Respond to User Access Requests - A method of data management for efficiently storing and retrieving data in response to user access requests. The method includes receiving a request from at least one client for a title not resident in a storage server, where the title includes a play track having a plurality of chapters. The retrieval from a secondary storage device of play track portions proximate chapter delineation points is initiated, and bandwidth capacity and quality-of-service (QoS) parameters associated with the secondary storage device is determined. In the case of a client request to begin presentation of the title at one of the chapters, streaming of retrieved portions of the play track chapter to the client is initiated, masking latency associated with the secondary storage device is provided, and retrieval of at least unretrieved portions of the play track chapter and subsequent play track portions from the secondary storage device is initiated. | 06-10-2010 |
20110040866 | METHOD OF DATA MANAGEMENT FOR EFFICIENTLY STORING AND RETRIEVING DATA TO RESPOND TO USER ACCESS REQUESTS - A method of data management for efficiently storing and retrieving data in response to user access requests. The method includes receiving a request from at least one client for a title not resident in a storage server, where the title includes a play track having a plurality of chapters. The retrieval from a secondary storage device of play track portions proximate chapter delineation points is initiated, and bandwidth capacity and quality-of-service (QoS) parameters associated with the secondary storage device is determined. In the case of a client request to begin presentation of the title at one of the chapters, streaming of retrieved portions of the play track chapter to the client is initiated, masking latency associated with the secondary storage device is provided, and retrieval of at least unretrieved portions of the play track chapter and subsequent play track portions from the secondary storage device is initiated. | 02-17-2011 |
20150067750 | Method of Data Management for Efficiently Storing and Retrieving Data to Respond to User Access Requests - A method of data management for efficiently storing and retrieving data in response to user access requests. The method includes receiving a request from at least one client for a title not resident in a storage server, where the title includes a play track having a plurality of chapters. The retrieval from a secondary storage device of play track portions proximate chapter delineation points is initiated, and bandwidth capacity and quality-of-service (QoS) parameters associated with the secondary storage device is determined. In the case of a client request to begin presentation of the title at one of the chapters, streaming of retrieved portions of the play track chapter to the client is initiated, masking latency associated with the secondary storage device is provided, and retrieval of at least unretrieved portions of the play track chapter and subsequent play track portions from the secondary storage device is initiated. | 03-05-2015 |
Patent application number | Description | Published |
20100030244 | Fixation band for affixing a prosthetic heart valve to tissue - A fixation band for affixing a prosthetic heart valve to tissue having proximal and distal annular portions positionable relative to one another, the proximal and distal annular portions each having a proximal and distal sides, the proximal side of the distal annular portion and the distal side of the proximal annular portion being oriented toward one another, and a prosthetic heart valve being attachable to one of the distal side of the distal annular portion and the proximal side of the proximal annular portion; staples configured between the distal side of the proximal annular portion and the proximal side of the distal annular portion; and a compression device operative between the proximal and distal annular portions for selectively positioning the proximal and distal annular members toward one another for compressing the staples therebetween and deploying the staples into tissue so as to affix the prosthetic heart valve to tissue. | 02-04-2010 |
20100036483 | Method and apparatus for improving mitral valve function - A method and apparatus for reducing mitral regurgitation. The apparatus is inserted into the coronary sinus of a patient in the vicinity of the posterior leaflet of the mitral valve, the apparatus being adapted to straighten the natural curvature of at least a portion of the coronary sinus in the vicinity of the posterior leaflet of the mitral valve, whereby to move the posterior annulus anteriorly and thereby improve leaflet coaptation and reduce mitral regurgitation. The apparatus is also configured to work in conjunction with an electrical lead for an implantable bi-ventricular pacing device, an electrical lead for an implantable cardio defibrillator, etc. | 02-11-2010 |
20100217384 | Method For Replacing Native Valve Function Of A Diseased Aortic Valve - Methods for replacing native valve function of a diseased aortic valve are disclosed. In an embodiment, a method for replacing native valve function of a diseased aortic valve in a patient includes: (a) receiving an artificial heart valve assembly mounted about a first mounting position on a catheter system, (b) guiding the artificial heart valve assembly through the vasculature of the patient, (c) while the catheter system having the artificial heart valve assembly mounted thereto is in the patient's vasculature, mounting the artificial heart valve assembly about a second mounting position on the catheter system, (d) delivering the artificial heart valve assembly to the region of the diseased aortic valve, (e) expanding the artificial heart valve assembly in the region of the diseased aortic valve, and (f) withdrawing the catheter system from the patient's vasculature. | 08-26-2010 |
20110118830 | System For Replacing Native Valve Function Of A Diseased Aortic Valve - Methods for replacing native valve function of a diseased aortic valve are disclosed. In an embodiment, a method for replacing native valve function of a diseased aortic valve in a patient includes: (a) receiving an artificial heart valve assembly mounted about a first mounting position on a catheter system, (b) guiding the artificial heart valve assembly through the vasculature of the patient, (c) while the catheter system having the artificial heart valve assembly mounted thereto is in the patient's vasculature, mounting the artificial heart valve assembly about a second mounting position on the catheter system, (d) delivering the artificial heart valve assembly to the region of the diseased aortic valve, (e) expanding the artificial heart valve assembly in the region of the diseased aortic valve, and (f) withdrawing the catheter system from the patient's vasculature. | 05-19-2011 |
20140257470 | METHOD AND APPARATUS FOR RESECTING AND REPLACING AN AORTIC VALVE - Apparatus for resecting a diseased heart valve, the apparatus comprising: a body portion; a first handle and a second handle; a cutting blade; a set of retaining arms; a pass-off tool having a first attachment device configured to selectively engage the first handle attached to the body portion so as to allow placement of the second handle of the body portion adjacent to the diseased heart valve, and a controller tool having a second attachment device at the distal end thereof, the second attachment device configured to selectively engage the second handle attached to the body portion so as to allow positioning of the body portion adjacent to the diseased heart valve, a cutting blade actuator configured to cause the cutting blade to selectively rotate, and a retaining arm actuator configured to selectively position the set of retaining arms from the contracted state to the expanded state. | 09-11-2014 |
Patent application number | Description | Published |
20090054632 | Hydrophobically-modified protein compositions and methods - Hydrophobically-modified proteins and methods of making them are described. A hydrophobic moiety is attached to a surface amino acid residue of the protein. The hydrophobic moiety can be a lipid or a peptide. Alternatively, the protein can be derivatized by a wide variety of chemical reactions that append a hydrophobic structure to the protein. The preferred protein is of mammalian origin and is selected from the group consisting of Sonic, Indian, and Desert hedgehog. The hydrophobic moiety is used as a convenient tether to which may be attached a vesicle such as a cell membrane, liposome, or micelle. | 02-26-2009 |
20090258420 | Altered polypeptides, immunoconjugates thereof, and methods related thereto - The present invention features inter alia altered binding polypeptides having engineered cysteine residues or analogs thereof at a predetermined site within, for example, a constant region domain or a portion thereof. The engineered cysteine residues or analogs thereof provide sites for conjugating effector moieties (e.g. diagnostic or therapeutic agents) that impart novel functionality to the binding polypeptide, preferably without interfering with a desirable property (e.g. an Fc-mediated effector function). The invention includes methods for the rational design of such altered polypeptides, as well as methods for modifying (ie. conjugating) the altered polypeptides with desirable effector moieties. Particular modified binding polypeptides (ie. immunoconjugates) of altered binding polypeptides and methods for utilizing such modified binding polypeptides as protein-based therapeutics are also provided. | 10-15-2009 |
20100104573 | BINDING PROTEINS, INCLUDING ANTIBODIES, ANTIBODY DERIVATIVES AND ANTIBODY FRAGMENTS, THAT SPECIFICALLY BIND CD154 AND USES THEREOF - This invention provides binding proteins, including antibodies, antibody derivatives and antibody fragments, that specifically bind a CD154 (CD40L) protein. This invention also provides a chimeric, humanized or fully human antibody, antibody derivative or antibody fragment that specifically binds to an epitope to which a humanized Fab fragment comprising a variable heavy chain sequence according to SEQ ID NO: 1 and comprising a variable light chain sequence according to SEQ ID NO: 2 specifically binds. CD154 binding proteins of this invention may elicit reduced effector function relative to a second anti-CD154 antibody. CD154 binding proteins of this invention are useful in diagnostic and therapeutic methods, such as in the treatment and prevention of diseases including those that involve undesirable immune responses that are mediated by CD154-CD40 interactions. | 04-29-2010 |
20100203046 | FC GAMMA RECEPTOR-BINDING POLYPEPTIDE VARIANTS AND METHODS RELATED THERETO - The compositions and methods of the present invention are based, in part, on our discovery that an effector function mediated by an Fc-containing polypeptide can be altered by modifying one or more amino acid residues within the polypeptide (by, for example, electrostatic optimization). The polypeptides that can be generated according to the methods of the invention are highly variable, and they can include antibodies and fusion proteins that contain an Fc region or a biologically active portion thereof. | 08-12-2010 |
20120003235 | ANTI-LYMPHOTOXIN ANTIBODIES - The instant invention is based, at least in part on the identification of a new class of antibodies that result, e.g., in improved LT blocking capabilities. Methods of making the subject binding molecules and methods of using the binding molecules of the invention to antagonize LTβR signaling are also provided. | 01-05-2012 |
20120100140 | STABILIZED FC POLYPEPTIDES WITH REDUCED EFFECTOR FUNCTION AND METHODS OF USE - A method of producing Fc-containing polypeptides, such as antibodies, having stabilized Fc regions is provided, together with stabilized Fc polypeptides produced according to these methods as well as methods of using such antibodies as therapeutics. | 04-26-2012 |
20120100575 | ANTIBODIES HAVING ALTERED EFFECTOR FUNCTION AND METHODS FOR MAKING THE SAME - The invention provides a method of producing aglycosylated Fc-containing polypeptides, such as antibodies, having desired effector function. The invention also provides aglycosylated antibodies produced according to the method as well as methods of using such antibodies as therapeutics. | 04-26-2012 |
20130045219 | BINDING PROTEINS, INCLUDING ANTIBODIES, ANTIBODY DERIVATIVES AND ANTIBODY FRAGMENTS, THAT SPECIFICALLY BIND CD154 AND USES THEREOF - This invention provides binding proteins, including antibodies, antibody derivatives and antibody fragments, that specifically bind a CD154 (CD40L) protein. This invention also provides a chimeric, humanized or fully human antibody, antibody derivative or antibody fragment that specifically binds to an epitope to which a humanized Fab fragment comprising a variable heavy chain sequence according to SEQ ID NO: 1 and comprising a variable light chain sequence according to SEQ ID NO: 2 specifically binds. CD154 binding proteins of this invention may elicit reduced effector function relative to a second anti-CD154 antibody. CD154 binding proteins of this invention are useful in diagnostic and therapeutic methods, such as in the treatment and prevention of diseases including those that involve undesirable immune responses that are mediated by CD154-CD40 interactions. | 02-21-2013 |
20140079716 | ANTI-LYMPHOTOXIN ANTIBODIES - The instant invention is based, at least in part on the identification of a new class of antibodies that result, e.g., in improved LT blocking capabilities. Methods of making the subject binding molecules and methods of using the binding molecules of the invention to antagonize LTβR signaling are also provided. | 03-20-2014 |
20140161794 | ANTI-VLA-4 ANTIBODIES - This invention relates to alpha-4 binding antibodies, and fragments thereof. | 06-12-2014 |
20140302016 | BINDING PROTEINS, INCLUDING ANTIBODIES, ANTIBODY DERIVATIVES AND ANTIBODY FRAGMENTS, THAT SPECIFICALLY BIND CD154 AND USES THEREOF - This invention provides binding proteins, including antibodies, antibody derivatives and antibody fragments, that specifically bind a CD154 (CD40L) protein. This invention also provides a chimeric, humanized or fully human antibody, antibody derivative or antibody fragment that specifically binds to an epitope to which a humanized Fab fragment comprising a variable heavy chain sequence according to SEQ ID NO: 1 and comprising a variable light chain sequence according to SEQ ID NO: 2 specifically binds. CD154 binding proteins of this invention may elicit reduced effector function relative to a second anti-CD154 antibody. CD154 binding proteins of this invention are useful in diagnostic and therapeutic methods, such as in the treatment and prevention of diseases including those that involve undesirable immune responses that are mediated by CD154-CD40 interactions. | 10-09-2014 |
20140341906 | HETERODIMERIC FC REGIONS, BINDING MOLECULES COMPRISING SAME, AND METHODS RELATING THERETO - The present invention features inter alia polypeptides comprising heterodimeric Fc regions. In addition, the instant invention provides methods for treating or preventing a disease or disorder in subject by administering the polypeptides of the invention to said subject. | 11-20-2014 |
20150017155 | AGLYCOSYL ANTI-CD154 (CD40 LIGAND) ANTIBODIES AND USES THEREOF - The invention relates to aglycosyl anti-CD154 antibodies or antibody derivatives, characterized by a modification at the conserved N-linked site in the C | 01-15-2015 |
Patent application number | Description | Published |
20080211782 | TOUCH SIMULATION SYSTEM AND METHOD - Systems and methods provide for simulating an effective touch on a touch screen sensor. A touch screen sensor includes a first surface, an opposing second surface, and one or more electrodes disposed on or proximate to the second surface. Signals are applied to the first and second surfaces in a manner which results in a simulated touch to a particular location of the touch screen sensor. In another approach, a plurality of voltage drive signals are applied at various touch surface regions of the touch screen sensor. A current flow resulting from application of the voltage drive signals is detected as the simulated touch. Touch simulation can be initiated locally or remotely as part of automated monitoring, testing, calibration, and/or servicing procedures. Results of a touch simulation procedure can be acquired and used locally or remotely to assess the operational fitness of the touch screen sensor over time. | 09-04-2008 |
20100097336 | TOUCH SYSTEMS AND METHODS UTILIZING CUSTOMIZED SENSORS AND GENERICIZED CONTROLLERS - Touch sensing circuit arrangements include a touch sensor and a controller board. The touch sensor includes one or more sensing elements to generate touch-related signals responsive to a touch input to the sensor, and a memory device storing computer-executable firmware instructions for determining touch positions based on the touch-related signals. The controller board includes query logic executable by the controller board to cause the controller board to query for the computer-executable firmware instructions stored on the memory device of the touch sensor, and a processor circuit to determine touch positions by executing the firmware instructions loaded onto the generic controller board in response to the query. | 04-22-2010 |
20120200506 | MODULAR CONNECTOR FOR TOUCH SENSITIVE DEVICE - Apparatus for providing modular connection means to electrodes in a touch-sensitive device. The modular connections may include electronics allowing controlling electronics to individually address electrodes associated with driving electrodes and sensing signals occurring on electrodes. | 08-09-2012 |
20130016072 | DIGITIZER FOR MULTI-DISPLAY SYSTEM - A multi-display system that uses back lights and light guides of an electronically addressable display to provide position-unique signals that both uniquely identify positions on a given display, but also uniquely identify displays within a multi-display system. | 01-17-2013 |
20140192490 | Modular Connector For Touch Sensitive Device - Apparatus for providing modular connection means to electrodes in a touch-sensitive device. The modular connections may include electronics allowing controlling electronics to individually address electrodes associated with driving electrodes and sensing signals occurring on electrodes. | 07-10-2014 |
Patent application number | Description | Published |
20080306406 | Single-Insertion, Multiple Sampling Biopsy Device With Linear Drive - The present invention provides for exemplary embodiments of a single-insertion, multiple sampling biopsy device. Exemplary embodiments of a single-insertion, multiple sampling device with integrated marker release. | 12-11-2008 |
20080319341 | Single-Insertion, Multiple Sample Biopsy Device with Integrated Markers - The present invention provides for exemplary embodiments of a single-insertion, multiple sample biopsy device. Exemplary embodiments of a single-insertion, multiple sampling device with integrated marker release. | 12-25-2008 |
20110098742 | SHAPE MEMORY FILAMENT FOR SUTURE MANAGEMENT - A member of a rigid flexible elastic material, the member including a body portion and an aperture portion with the member adapted for delivery through an axial longitudinal channel of a percutaneous delivery subsystem, the aperture portion including an expanded mode having a lateral dimension greater than an inner diameter of the channel when the aperture portion extends outside the channel and a collapsed mode wherein the lateral dimension is not greater than the inner diameter of the channel when the aperture portion is within the channel, the channel including a first axial opening and a second axial opening with the aperture portion transitioning from the expanded mode to the collapsed mode when inserted into the openings and the aperture transitioning from the collapsed mode to the expanded mode when exiting from the openings. | 04-28-2011 |
20110275998 | SYSTEMS AND METHODS FOR DELIVERING A THERAPEUTIC AGENT - Devices and methods for delivering a fluid to a patient are disclosed herein. In one embodiment, a delivery system includes a reservoir for containing a fluid and a fluid communicator in fluid communication with the reservoir. An electrochemical actuator is coupled to the reservoir and configured to exert a force on the reservoir upon actuation such that fluid within the reservoir is communicated through the fluid communicator. The actuator includes a first end that is constrained and a second end that is not constrained. The actuator is configured to bend at a location along a length of the actuator when actuated such that the second end of the actuator is displaced in a direction toward the fluid reservoir. The actuator can be an electrochemical actuator. The apparatus can further include a transfer structure disposed between the actuator and the reservoir configured to contact the reservoir upon actuation of the actuator. | 11-10-2011 |
20120323120 | SINGLE-INSERTION, MULTIPLE SAMPLE BIOPSY DEVICE WITH INTEGRATED MARKERS - The present invention provides for exemplary embodiments of a single-insertion, multiple sample biopsy device. Exemplary embodiments of a single-insertion, multiple sampling device with integrated marker release. | 12-20-2012 |
20120323140 | SINGLE-INSERTION, MULTIPLE SAMPLE BIOPSY DEVICE WITH INTEGRATED MARKERS - The present invention provides for exemplary embodiments of a single-insertion, multiple sample biopsy device. Exemplary embodiments of a single-insertion, multiple sampling device with integrated marker release. | 12-20-2012 |
20120330185 | SINGLE-INSERTION, MULTIPLE SAMPLING BIOPSY DEVICE USABLE WITH VARIOUS TRANSPORT SYSTEMS AND INTEGRATED MARKERS - A biopsy device includes a biopsy sample extraction needle with a sample extraction end and a recovery end. A transport channel links the extraction end and recovery end. A pump is provided, and a multi-way valve is coupled in fluid communication with the biopsy sample extraction needle and the pump. The multi-way valve has a plurality of settings. | 12-27-2012 |
20130023791 | SINGLE-INSERTION, MULTIPLE SAMPLING BIOPSY DEVICE WITH LINEAR DRIVE - The present invention provides for exemplary embodiments of a single-insertion, multiple sampling biopsy device. Exemplary embodiments of a single-insertion, multiple sampling device with integrated marker release. | 01-24-2013 |
20140350470 | SYSTEMS AND METHODS FOR DELIVERING A THERAPEUTIC AGENT - Devices and methods for delivering a fluid to a patient are disclosed herein. In one embodiment, a delivery system includes a reservoir for containing a fluid and a fluid communicator in fluid communication with the reservoir. An electrochemical actuator is coupled to the reservoir and configured to exert a force on the reservoir upon actuation such that fluid within the reservoir is communicated through the fluid communicator. The actuator includes a first end that is constrained and a second end that is not constrained. The actuator is configured to bend at a location along a length of the actuator when actuated such that the second end of the actuator is displaced in a direction toward the fluid reservoir. The actuator can be an electrochemical actuator. The apparatus can further include a transfer structure disposed between the actuator and the reservoir configured to contact the reservoir upon actuation of the actuator. | 11-27-2014 |
20140371585 | SINGLE-INSERTION, MULTIPLE SAMPLING BIOPSY DEVICE WITH LINEAR DRIVE - The present invention provides for exemplary embodiments of a single-insertion, multiple sampling biopsy device. Exemplary embodiments of a single-insertion, multiple sampling device with integrated marker release. | 12-18-2014 |
20150065587 | NUTRACUETICAL COMPOUNDING SYSTEM AND METHOD THEREFORE - The present invention relates to a system and process for a nutracuetical beverage compounding system and methods for the same. Provided is a customizable supplement beverage system and method for personalizing and operating the same to a particular user and optionally for operative tracking. Proposed additionally is an operative system for receiving and individually identifying a concentrate or supplement combinations, for mixing the same prior to a use, and for dispensing the same for use, and for tracking control factors relating to the same. | 03-05-2015 |
Patent application number | Description | Published |
20090118739 | Method and Device for Manipulation of an Intraocular Lens - A method for charging a deformable intraocular lens into a receptacle through a slit or opening in the receptacle periphery, the lens in un-deformed state comprising a) a roughly disc shaped optic part configured to act as a lens when inserted into an eye and b) at least two elongated haptic legs, each leg having an inner end attached to the optic part, an outer end being free and intermediate points in between the inner end and the free end, each leg being curved in unstressed state and being flexible to at least a less curved configuration under stress. The method comprises the steps of i) stretching the legs to align the legs along a substantially straight line, ii) aligning or maintaining the substantially straight line over and substantially parallel with the slit or opening of the receptacle, and iii) transferring at least the two legs through the slit or opening into the receptacle. A device for stretching the haptics of a lens comprises i) at least two haptic guiding surfaces arranged for each of the at least two haptic legs, the guiding surfaces having less curvature than the legs in un-stressed state, ii) a seat for the lens arranged with respect to the guiding surfaces so as to allow, when a lens is positioned in the seat, contact between a first point on the leg and its guiding structure and iii) a lens guiding arrangement allowing the lens to be moved along a path bringing at least a second point on the leg into contact with, or closer to, its guiding structure or a transfer opening allowing passage of the lens with the haptics, having said less curvature, to a receptacle. | 05-07-2009 |
20130103040 | METHOD AND DEVICE FOR MANIPULATION OF AN INTRAOCULAR LENS - A method for charging a deformable intraocular lens into a receptacle through a slit or opening in the receptacle periphery, the lens in un-deformed state comprising a) a roughly disc shaped optic part configured to act as a lens when inserted into an eye and b) at least two elongated haptic legs, each leg having an inner end attached to the optic part, an outer end being free and intermediate points in between the inner end and the free end, each leg being curved in unstressed state and being flexible to at least a less curved configuration under stress. The method comprises the steps of i) stretching the legs to align the legs along a substantially straight line, ii) aligning or maintaining the substantially straight line over and substantially parallel with the slit or opening of the receptacle, and iii) transferring at least the two legs through the slit or opening into the receptacle. A device for stretching the haptics of a lens comprises i) at least two haptic guiding surfaces arranged for each of the at least two haptic legs, the guiding surfaces having less curvature than the legs in un-stressed state, ii) a seat for the lens arranged with respect to the guiding surfaces so as to allow, when a lens is positioned in the seat, contact between a first point on the leg and its guiding structure and iii) a lens guiding arrangement allowing the lens to be moved along a path bringing at least a second point on the leg into contact with, or closer to, its guiding structure or a transfer opening allowing passage of the lens with the haptics, having said less curvature, to a receptacle. | 04-25-2013 |
Patent application number | Description | Published |
20100069833 | CATHETER SYSTEM - A robotic catheter system is provided. The robotic catheter system includes a housing and a drive assembly coupled to the housing. The drive assembly is configured to impart movement to a catheter device. The catheter system includes a release structure permitting the drive assembly to be decoupled and removed from the housing without removing the catheter device from a patient. | 03-18-2010 |
20100076308 | CATHETER SYSTEM - A robotic catheter system is provided. The catheter system includes a housing, and the housing has a sidewall and a longitudinal axis. The catheter system includes a recess formed in the sidewall of the housing and a drive mechanism supported by the housing. The drive mechanism is configured to impart movement to a catheter device. The catheter system includes a first channel configured to receive a catheter device, and the first channel has a opening located within the recess. | 03-25-2010 |
20100076309 | CATHETER SYSTEM - A catheter system including a housing and a drive mechanism supported by the housing is provided. The drive mechanism includes an engagement structure configured to engage and to impart movement to a catheter device. The engagement structure defines a path for the catheter device, and the engagement structure is moveable between an engaged position in which the engagement structure engages the catheter device and a disengaged position in which the engagement structure does not engage the catheter device. The catheter system includes a biasing element configured to bias the engagement structure toward the engaged position, and the biasing element is aligned generally parallel to the path defined by the engagement structure. | 03-25-2010 |
20100076310 | CATHETER SYSTEM - A catheter system including a housing and a first drive mechanism supported by the housing configured to impart movement to a first catheter device is provided. The first drive mechanism is moveable between an engaged position in which the first drive mechanism engages the first catheter device and a disengaged position in which the first drive mechanism does not engage the first catheter device. The catheter system includes a second drive mechanism supported by the housing configured to impart movement to a second catheter device. The second drive mechanism is moveable between an engaged position in which the second drive mechanism engages the second catheter device and a disengaged position in which the second drive mechanism does not engage the second catheter device. The catheter system includes a manual control configured to allow a user to manually move the first drive mechanism and the second drive mechanism between the engaged and disengaged positions. The first drive mechanism and the second drive mechanism are also configured to be moved between the engaged and disengaged positions by an electronic actuator responsive to a user's activation of a control. The first drive mechanism and the second drive mechanism are configured to be moved between the respective engaged and disengaged positions synchronized with each other. | 03-25-2010 |
20100130987 | CATHETER SYSTEM - A robotic catheter system includes a housing and a drive assembly. The drive assembly is supported by the housing and configured to impart movement to a catheter device and includes a first channel configured to receive the catheter device. The robotic catheter system includes at least one magnet positioned adjacent to the first channel to allow the magnet to interact with the catheter device to assist in the retention of the catheter device within the first channel. | 05-27-2010 |
20130236354 | Constricting Pressure Valve Apparatus and Methods Thereof - A valve apparatus and methods associated thereof are provided. The valve apparatus includes a valve housing structure. A first valve portion is connected to the valve housing structure, wherein the first valve portion has a sealing edge. A second valve portion is positioned at least partially within the valve housing structure. A constrictable membrane has a pressurizable interior compartment, wherein the constrictable membrane supported by the second valve portion and positioned proximate to the first valve portion, wherein at least a portion of the constrictable membrane is movable to engageable with the sealing edge of the first valve portion. | 09-12-2013 |
20140058322 | CATHETER SYSTEM - A robotic catheter system is provided. The robotic catheter system includes a housing and a drive assembly coupled to the housing. The drive assembly is configured to impart movement to a catheter device. The catheter system includes a release structure permitting the drive assembly to be decoupled and removed from the housing without removing the catheter device from a patient. | 02-27-2014 |
20140155899 | SURGICAL INSTRUMENT - A cannulated retrograde reamer that is adjustable to create tunnels of multiple different diameters. The cannulated retrograde reamer substantially reduces the risk of tunnel malposition and/or misalignment, and can be adjusted to create a range of tunnel diameters, thereby allowing inventory levels to be reduced for a surgical case. | 06-05-2014 |
Patent application number | Description | Published |
20110318324 | METHODS AND COMPOSITIONS FOR CNS DELIVERY OF B-GALACTOCEREBROSIDASE - The present invention provides, among other things, compositions and methods for CNS delivery of lysosomal enzymes for effective treatment of lysosomal storage diseases. In some embodiments, the present invention includes a stable formulation for direct CNS intrathecal administration comprising an B-Galactocerebrosidase protein, salt, and a polysorbate surfactant for the treatment of GLD Disease. | 12-29-2011 |
20120009171 | METHODS AND COMPOSITIONS FOR CNS DELIVERY OF ARYLSULFATASE A - The present invention provides, among other things, compositions and methods for CNS delivery of lysosomal enzymes for effective treatment of lysosomal storage diseases. In some embodiments, the present invention includes a stable formulation for direct CNS intrathecal administration comprising an arylsulfatase A (ASA) protein, salt, and a polysorbate surfactant for the treatment of Metachromatic Leukodystrophy Disease. | 01-12-2012 |
20130295071 | METHODS AND COMPOSITIONS FOR CNS DELIVERY OF B-GALACTOCEREBROSIDASE - The present invention provides, among other things, compositions and methods for CNS delivery of lysosomal enzymes for effective treatment of lysosomal storage diseases. In some embodiments, the present invention includes a stable formulation for direct CNS intrathecal administration comprising an B-Galactocerebrosidase protein, salt, and a polysorbate surfactant for the treatment of GLD Disease. | 11-07-2013 |
20140377244 | STABLE FORMULATIONS FOR CNS DELIVERY OF ARYLSULFATASE A - The present invention provides, among oilier things, compositions and methods for CNS delivery of lysosomal enzymes (e.g., recombinant human arylsulfatase A (rhASA)) for effective treatment of lysosomal storage diseases (e.g. Metachromatic Leukodystrophy Disease). In some embodiments, the present invention includes a stable formulation for intrathecal administration comprising an ASA protein and a poloxamer, wherein less than 3% of the ASA protein exists in aggregated form. | 12-25-2014 |
Patent application number | Description | Published |
20090043242 | INSTRUMENTS AND METHODS FOR IMPLANTING CORNEAL IMPLANT VIA EXTRA-AND INTRA-CAMERAL ROUTES - A method of implanting a transcorneal shunt into a cornea, the shunt having a head and a foot, each having a hole therein, the method including the operations of engaging an insertion tool with a foot hole of the shunt; making an entry incision in the cornea; inserting the shunt, while still engaged with the insertion tool, through the entry incision; making an implant incision in the cornea; inserting the head of the shunt through the implant incision to position and seat the shunt; and releasing the shunt from the insertion tool. | 02-12-2009 |
20090131848 | METHOD FOR IMPLANTING A TRANSCORNEAL IMPLANT THROUGH A PARACENTESIS T-INCISION, AND TRANSCORNEAL IMPLANT SO IMPLANTED - A method for implanting a transcorneal implant having a cap, a foot, and a body connecting the cap and the foot, the body having a lesser circumference than either the cap or the foot, the method including the operations: creating a first corneal incision to create a tunnel, such that the a far end of the first incision enters the anterior chamber; creating a second corneal incision opening a roof of the tunnel to an end point past the far end of the first incision and creating flaps; guiding the implant to the end point, so that the foot of the implant is under the flaps; rotating the implant until the foot is entirely within the anterior chamber; and rotating the implant back to a neutral position, such that a portion of the foot is beneath a floor of the tunnel. | 05-21-2009 |
20120041373 | Needle Changing Apparatus - An apparatus is disclosed for storing and changing needles for connection with a medicament delivery device, comprising an inner housing, a reservoir disposed within the inner housing, and a needle holder disposed within the inner housing, for fluidly connecting a medicament container of the medicament delivery device with the reservoir. The apparatus also includes a plurality of patient needles displaceably disposed on the needle holder, and an outer housing displaceably disposed about the inner housing and providing a user interface to individually select one of the plurality of patient needles, connect the selected needle with the reservoir, expose the selected needle outside of the apparatus for injection, and store the selected needle. | 02-16-2012 |
20120041383 | Circuitous Band Needle Changing Apparatus - An apparatus is disclosed for storing and changing needles for a medicament delivery device having a medicament container, including a fixed mount for connecting the apparatus with the medicament delivery device, a needle holder displaceable along a circuitous path and connecting a plurality of needles displaceably disposed thereon, and a guide member for guiding displacement of the needle holder, the guide member being disposed about the fixed mount. The apparatus also includes a user interface rotatably disposed about the fixed mount and having at least one internal engaging structure for displacing the needle holder along the circuitous path. | 02-16-2012 |
20120041385 | Attachable Needle Changing Device For Medicament Delivery Device - An attachable needle storage device is provided with a main body and a rotatable sleeve and a plurality of new needles stored within the sleeve, a leaf spring to direct each needle into a circumferential position of the pen body when rotated, and a ramp to move the needle into an axial position of the pen body when retracted or pulled rearward by the user. The attachable needle storage device is configured to attach to a pen device in a manner substantially the same as a conventional needle hub. In doing so, the rotation of the sleeve can be used to rotate a new needle onto a shuttle, and the retraction of the device can be used to cause a ramp to engage the needle and needle hub, moving the needle toward the axial position of the pen body and the septum. Once under the septum, the user continues pulling the device rearward, such that the needle is then moved rearward, pierces the septum of the medicament cartridge and exposes the distal end of the needle for injection. After use, a needle shield is used to unlock a compressed spring, which is configured to pull the needle from the septum, and return the device to the transport state, after which the previous steps can be repeated. | 02-16-2012 |
20130006216 | LOW DOSE PREFILLED DRUG DELIVERY DEVICE AND METHOD - A drug delivery device ( | 01-03-2013 |
Patent application number | Description | Published |
20140353558 | MIXED CATALYST SYSTEMS AND METHODS FOR CHEMILUMINESCENT REACTIONS - In some embodiments, the instant invention provides a chemiluminescent system, including: an activator system, including: (a) at least one first catalyst including at least one benzyl amine; (b) at least one second catalyst including at least one of: (i) a salicylate derivative, and (ii) a benzoate derivative; (c) at least one first solvent, and (d) at least one peroxide, where the at least one first catalyst is present in an amount ranging from 1 to 99 percent by weight of a combination of the at least one first catalyst and the at least one second catalyst; where the at least one second catalyst is present in an amount ranging from 99 to 1 percent by weight of the combination of the at least one first catalyst and the at least one second catalyst; and where the chemiluminescent system has at least one chemiluminescent property. | 12-04-2014 |
20140353559 | BROAD TEMPERATURE PERFORMANCE CHEMILUMINESCENT SYSTEMS AND METHODS - In some embodiments, the present invention is a chemiluminescent system, including: an oxalate system, including: (a) at least one oxalate ester, (b) at least one first solvent selected from the group consisting of alkyl benzoates, dialkyl phthalates, trialkyl acetylcitrates, 2-acetyloxy isobutyrates, paraffinic liquids, isoparaffinic liquids, toluene, nitroethane, and a combination thereof, (c) at least one second solvent selected from the group consisting of: dialkyl malonates, dialkyl dialkylmalonates, dialkyl arylalkylmalonates, dialkyl succinates, dialkyl glutarates, dialkyl adipates, dialkyl pimelates, dialkyl polyalkylmalonates and a combination thereof, (d) at least one fluorescer, and (e) at least one inorganic salt, and an activator system, including: (a) at least one peroxide, (b) at least one third solvent, (c) at least one fourth solvent, and (d) at least one catalyst. | 12-04-2014 |
20140353560 | LOW TEMPERATURE OXALATE SYSTEMS AND METHODS FOR CHEMILUMINESCENT REACTIONS - In some embodiments, the instant invention provides a chemiluminescent system, including: an oxalate system, including: (a) at least one oxalate ester in an amount ranging from 3 to 60 percent by weight based on a total weight of the oxalate system, (b) at least one first solvent selected from the group consisting of: alkyl benzoates, dialkyl phthalates, trialkyl acetylcitrates, 2-acetyloxy isobutyrates, paraffinic liquids, isoparaffinic liquids, toluene, nitroethane, in an amount ranging from 10 to 97 percent by weight based on the total weight of the oxalate system, (c) at least one second solvent is selected from the group consisting of: dialkyl malonates, dialkyl dialkylmalonates, dialkyl arylalkylmalonates, dialkyl succinates, dialkyl glutarates, dialkyl adipates, dialkyl pimelates, dialkyl polyalkylmalonates, (d) at least one fluorescer, and (e) at least one inorganic salt in an amount ranging from 0.1 to 30 percent by weight based on the total weight of the oxalate system. | 12-04-2014 |
20140356975 | LOW TEMPERATURE ACTIVATOR SYSTEMS AND METHODS FOR CHEMILUMINESCENT REACTIONS - In some embodiments, the instant invention provides a chemiluminescent system, including: an activator system, including: (a) at least one first solvent, (b) at least one peroxide, (c) at least one catalyst, (d) at least one second solvent, where the at least one second solvent is selected from the group consisting of: tert-butanol, 3-methyl-3-pentanol, 2-methyl-2-butanol, ethyl 2-hydroxyisobutyrate, methyl 2-hydroxyisobutyrate, ethylene glycol, propylene glycol, ethylene glycol monomethyl ether, ethylene glycol diethyl ether, ethylene glycol monobutyl ether, ethylene glycol dibutyl ether, propylene glycol dimethyl ether, and a combination thereof; where a combination of the at least one first solvent and the at least one second solvent is present in a sufficient amount in the chemiluminescent system so as to result in the chemiluminescent system producing a light having an illuminescence between 0.1 1× and 35,000 1× at a temperature ranging from −110 degrees Celsius to 75 degrees Celsius. | 12-04-2014 |
Patent application number | Description | Published |
20120306852 | Producing Three-Dimensional Graphics - A system includes a computing device for producing a representation of a graphical element on a two dimensional set of image points. A metric value is calculated for each image point in the two dimensional set of image points. The computer device is configured to assign a visual property to image point in the two dimensional set of image points based upon the corresponding metric value. The computing device is also configured to present the assigned visual properties of the two dimensional set of image points as being offset from another two dimensional set of image points to provide a three dimensional appearance of the graphical element. | 12-06-2012 |
20140043339 | Producing Glyph Distance Fields - A system includes a first computing device that includes a memory configured to store instructions. The first computing device also includes a processor to execute the instructions to perform a method that includes receiving data representing a collection of line segments that represent a glyph. The method also includes, for each line segment, defining a cell that substantially encapsulates the line segment. At least one side of the cell is defined by bisecting an angle defined by the line segment and an adjacent line segment. The method also includes determining a value for a portion of the defined cell based upon the distance between the portion of the cell and the corresponding line segment. | 02-13-2014 |
20140354643 | PRODUCING THREE-DIMENSIONAL GRAPHICS - A system includes a computing device for producing a representation of a graphical element on a two dimensional set of image points. A metric value is calculated for each image point in the two dimensional set of image points. The computer device is configured to assign a visual property to image point in the two dimensional set of image points based upon the corresponding metric value. The computing device is also configured to present the assigned visual properties of the two dimensional set of image points as being offset from another two dimensional set of image points to provide a three dimensional appearance of the graphical element. | 12-04-2014 |
20150062140 | Dynamically Adjustable Distance Fields for Adaptive Rendering - A system includes a computing device that includes a memory configured to store instructions. The computing device also includes a processor to execute the instructions to perform operations that include receiving data representing a portion of a graphical object, and receiving data representative of one or more environmental conditions. For the portion of the graphical object, operations include defining a field of scalar values for presenting the graphical object on a display. Each scalar value is based on a distance between the portion of the graphical object and a corresponding point. Operations also include calculating one or more visual property values based on the scalar values and the one or more environmental conditions, and presenting the graphical object using the calculated visual property values of the field. | 03-05-2015 |
Patent application number | Description | Published |
20080290040 | Methods and Apparatus for Foam Control in a Vacuum Filtration System - A flow diverter, vacuum control and tilting of the liquid filtering system are used alternatively or in conjunction to reduce foam production in a filtered liquid sample. A liquid filtering system includes an upper sample reservoir, a filter and a lower storage bottle. A vacuum is applied below the sample filter to draw sample liquid through the sample filter into the storage bottle. A flow diverter may be used to direct flow of the filtered liquid sample onto a sidewall of the storage bottle or guide flow to a bottom of the storage bottle. The vacuum may be regulated to reduce foaming. The liquid filtering system may be tilted to direct fluid to the sidewall of the lower storage bottle and reduce foaming. | 11-27-2008 |
20090026126 | Vacuum Base and Related Methods and Apparatus for Vacuum Filtration - Liquid filter assemblies including an upper sample reservoir, a sample filter and a lower storage bottle are supported by a vacuum base. The base has a vacuum inlet port and, for connection to the liquid filter assembly, a vacuum outlet port. A vacuum is provided through the base to below the sample filter to draw sample liquid through the sample filter into the storage bottle. The base may include an auxiliary vacuum outlet port for connection with additional devices. The bases may be connected from one to another through auxiliary vacuum outlets and the vacuum inlets to make a chain of liquid filter assemblies supplied from one vacuum source. Alternatively, one base may include multiple vacuum outlet ports so that it may support and supply vacuum to a plurality of liquid filter assemblies. | 01-29-2009 |
20090026153 | Method and apparatus for filtrate storage handling - A method of removing a filtrate storage bottle from a water bath includes inserting at least two finger underneath a radially protruding lip of a filtrate storage bottle sealing cap and raising the at least two fingers to lift the bottle from the water bath. A side wall portion of the filtrate storage bottle sealing cap is smaller in perimeter than a circle surrounding the radially protruding lip. The cap creates a liquid tight seal with the filtrate storage bottle. | 01-29-2009 |
20090026154 | Methods and Apparatus for Supporting a Vacuum Filtration Device - A portable fixture for supporting a vacuum filtration device includes a cradle portion and a clamping portion. The cradle portion supports the vacuum filtration device. The clamping portion removeably attaches the portable fixture to a support in order to secure and support the filtration device above a workspace. The portable fixture may also provide a vacuum to the filtration device. To that end, the portable fixture may have a vacuum inlet port which may be connected to a vacuum source and a vacuum outlet port that is fluidly connected to the vacuum inlet port. | 01-29-2009 |
20090215150 | Sample container and filtration apparatus and method of filtration using the same - A sample container and filtration apparatus is described comprising a sealable sample container and a surface that is configured to interface with a vacuum base. When the surface interfaces with the vacuum base, a portion of the sample container is broached, providing a pathway for the vacuum source to pull the sample therethrough. In exemplary embodiments, the broachable portion of the sample container comprises an actuating valve. The method for using the sample container and filtration apparatus significantly reduces the possibility of contamination of the sample and during the sample testing procedure relative to the conventional devices and procedures, provides more consistent and reliable test results, and significantly reduces the number of preparation and testing steps for the testing procedure. | 08-27-2009 |
20120267301 | Method and Apparatus for Filtrate Storage Handling - A method of removing a filtrate storage bottle from a water bath includes inserting at least two finger underneath a radially protruding lip of a filtrate storage bottle sealing cap and raising the at least two fingers to lift the bottle from the water bath. A side wall portion of the filtrate storage bottle sealing cap is smaller in perimeter than a circle surrounding the radially protruding lip. The cap creates a liquid tight seal with the filtrate storage bottle. | 10-25-2012 |
20120294781 | Vacuum Base and Related Methods and Apparatus for Vacuum Filtration - Liquid filter assemblies including an upper sample reservoir, a sample filter and a lower storage bottle are supported by a vacuum base. The base has a vacuum inlet port and, for connection to the liquid filter assembly, a vacuum outlet port. A vacuum is provided through the base to below the sample filter to draw sample liquid through the sample filter into the storage bottle. The base may include an auxiliary vacuum outlet port for connection with additional devices. The bases may be connected from one to another through auxiliary vacuum outlets and the vacuum inlets to make a chain of liquid filter assemblies supplied from one vacuum source. Alternatively, one base may include multiple vacuum outlet ports so that it may support and supply vacuum to a plurality of liquid filter assemblies. | 11-22-2012 |
20130139617 | Sample Container and Filtration Apparatus and Method of Filtration Using Same - A sample container and filtration apparatus includes a sample container portion with an interior volume and a fluid path passing through a bottom wall. The sample container may also include a valve casing connected to and moveable relative to the sample collection portion between a first and second position. A valve secured to and moveable with the valve casing may close the fluid path of the sample collection portion when in a first position and open the fluid path when in a second position. The apparatus may also include a vacuum base coupling portion that is distal to the valve casing, and includes a filter membrane support surface for supporting a filter membrane. | 06-06-2013 |
20140109526 | Carboy With Permanent Closure and Method of Filling a Carboy - A carboy has a rigid body forming an interior chamber for receiving a liquid. The chamber has a wall terminating at an opening and maintains a substantially constant shape at room temperature. The carboy also has a closure permanently secured to the opening for forming a sealed connection with the rigid body, and a plurality of tubes extending from the plurality of ports in the closure to fluidly connect with a carboy circuit. The closure has a plurality of ports for selectively providing access to the interior chamber, where at least one of the tubes extends out of the interior chamber. The at least one tube also extends inwardly from the closure and into the interior chamber. | 04-24-2014 |
Patent application number | Description | Published |
20120150123 | INFUSION SET - A single package infusion set is provided, including one or more of the following inserters: pushbutton-type, squeeze-type, contact-type, skin pinching-type, folding retraction-type, or multistage-type inserter having at least one reusable stage. The infusion set further includes adhesion means with user-selectable degrees of adhesion strength, self-sealing tube connection means, a lens feature to view, a site beneath the set, exemplary tube management and connection elements, insulin supply, adhesion concealment means, finger loops on the inserter and site preparation wipes or sprays, optionally provided as part of the inserter. The system further includes a package which may hold a number of easily released sets, retrievable by an inserter, an exemplary insertion needle handle and shroud, an exemplary squeeze-type latch between an upper portion and a lower portion of the set, and/or a tool removable upper portion of the set. | 06-14-2012 |
Patent application number | Description | Published |
20120297899 | Chromatography Apparatus And Method - Sample preparation device for receiving in sealing relation one or more filter assemblies and one or more sample containers, each container uniquely positioned within the device to receive filtered sample from a designated filter. The device includes a body, a lid disposed on the body, a container tray, a base, an integrated seal on the body, a valve and a valve actuator. The tray can be disposed in a vacuum chamber defined by the lid and the body, and one or more sample containers can be disposed in the tray. When properly positioned in the tray in the vacuum chamber, each container is in fluid communication with a single respective filter assembly disposed in sealing relation in a respective aperture in the lid. A single actuation of a valve causes the lid to seal to the base and drives the simultaneous filtration of a plurality of samples. | 11-29-2012 |
20140105795 | Chromatography Apparatus And Method - Sample preparation device for receiving in sealing relation one or more filter assemblies and one or more sample containers, each container uniquely positioned within the device to receive filtered sample from a designated filter. The device includes a body, a lid disposed on the body, a container tray, a base, an integrated seal on the body, a valve and a valve actuator. The tray can be disposed in a vacuum chamber defined by the lid and the body, and one or more sample containers can be disposed in the tray. When properly positioned in the tray in the vacuum chamber, each container is in fluid communication with a single respective filter assembly disposed in sealing relation in a respective aperture in the lid. A single actuation of a valve to place the vacuum chamber under vacuum causes the lid to seal to the base and drives the simultaneous filtration of a plurality of samples. | 04-17-2014 |
20140298924 | Chromatography Apparatus And Method - Sample preparation device for receiving in sealing relation one or more filter assemblies and one or more sample containers, each container uniquely positioned within the device to receive filtered sample from a designated filter. The device includes a body, a lid disposed on the body, a container tray, a base, an integrated seal on the body, a valve and a valve actuator. The tray can be disposed in a vacuum chamber defined by the lid and the body, and one or more sample containers can be disposed in the tray. When properly positioned in the tray in the vacuum chamber, each container is in fluid communication with a single respective filter assembly disposed in sealing relation in a respective aperture in the lid. A single actuation of a valve to place the vacuum chamber under vacuum causes the lid to seal to the base and drives the simultaneous filtration of a plurality of samples. | 10-09-2014 |
Patent application number | Description | Published |
20140270221 | Sealing Wiring Holes in Electronic Devices - A wall separates a first volume from a second volume and has a hole allowing passage between the first volume and the second volume. A wire passes through the hole, and a gasket surrounds the wire at the hole. The gasket includes a first section including a groove between a first flange and a second flange, the groove has an outer diameter matched to the diameter of the hole and the flanges have outer diameters greater than the diameter of the hole. A second section adjacent the first flange includes a tubular portion having a diameter less than the diameter of the hole and a tapered section smoothly transitioning from the diameter of the tubular portion to the diameter of the first flange. The gasket prevents flow of fluid through the hole between the first volume and the second volume. | 09-18-2014 |
20140294223 | Headset Porting - A headset cup having a front cavity and a rear cavity separated by a driver, with a mass port tube connected to the rear port to present a reactive acoustic impedance to the rear cavity, in parallel with a resistive port, the total acoustic response of the rear cavity remaining linear at high power levels. In some embodiments, the mass port tube is made of metal, while the headset cup is otherwise made of plastic. | 10-02-2014 |
20150063601 | Assisting Conversation while Listening to Audio - A portable system for enhancing communication between users in proximity to each other while listening to a common audio source includes headsets with an electroacoustic transducer for providing sound to a respective user's ear, and a voice microphone for detecting sound of the respective user's voice and providing a microphone input signal, and an electronic device integral to the first headset and in communication with the second headset. The electronic device generates a side-tone signal based on the microphone input signal from the first headset, generates a voice output signal based on the microphone input signal from the first headset, receives a content input signal, combines the side-tone signal with the content input signal and a far-end voice signal associated with the second headset to generate a combined output signal, and provides the combined output signal to the first headset for output by the first headset's transducer. | 03-05-2015 |