Patent application number | Description | Published |
20090062227 | METHODS AND COMPOSITIONS FOR INDUCING APOPTOSIS BY STIMULATING ER STRESS - The present invention provides a method for inducing apoptosis in selected cells by aggravating ER-stress. The aggravation of ER-stress is achieved in a specific manner by inhibiting SERCA (sarcoplasmic/endoplasmic reticulum calcium ATPase), leading to elevated level of cytoplasmic calcium concentration, yet without inhibiting the activity of COX-2 (cyclooxygenase-2) or triggering the release of histamine. Induction of apoptosis may be enhanced by first inducing or further aggravating ER-stress through inhibition of proteasome or proteases. Also provided are compounds and compositions useful as ER-stress aggravating agents, methods for screening, selecting, identifying and designing the same and methods for treating diseased conditions by inducing apoptosis through specific and selective aggravation of ER-stress. | 03-05-2009 |
20090318902 | Magnetic Breather Pump and a Method for Treating a Brain Tumor Using the Same - A magnetically controlled pump is implanted into the brain of a patient and delivers a plurality of medicating agents at a controlled rate corresponding to the specific needs of the patient. The current invention comprises a flexible double walled pouch that is formed from two layers of polymer. The pouch is alternately expanded and contracting by magnetic solenoid. When contracted, a medicating agent is pushed out of the pouch through a plurality of needles. When the pouch is expanded, surrounding cerebral fluid is drawn into the space between the double walls of the pouch from which it is drawn through a catheter to an analyzer. Cerebral fluid drawn from the patient is analyzed. The operation of the apparatus and hence the treatment is remotely controlled based on these measurements and displayed through an external controller. | 12-24-2009 |
20090318903 | Magnetic Breather Pump and a Method for Treating a Brain Tumor Using the Same - A magnetically controlled pump is implanted into the brain of a patient and delivers a plurality of medicating agents at a controlled rate corresponding to the specific needs of the patient. The current invention comprises a flexible double walled pouch that is formed from two layers of polymer. The pouch is alternately expanded and contracting by magnetic solenoid. When contracted, a medicating agent is pushed out of the pouch through a plurality of needles. When the pouch is expanded, surrounding cerebral fluid is drawn into the space between the double walls of the pouch from which it is drawn through a catheter to an analyzer. Cerebral fluid drawn from the patient is analyzed. The operation of the apparatus and hence the treatment is remotely controlled based on these measurements and displayed through an external controller. | 12-24-2009 |
20110092948 | Remotely Activated Piezoelectric Pump for Delivery of Biological Agents to the Intervertebral Disc and Spine - The present disclosure describes a remotely activated piezoelectric pump for delivery of biological agents to the intervertebral disc and spine in order to achieve spinal fusion. A spinal pump is implanted on the vertebrae of a patient and a spinal cage is inserted in between two adjacent vertebrae after removal of the vertebrae disc. A piezoelectric motor drives the pump and pushes osteogenetic agent through the spinal cage and into a sponge disposed within the cage. The pump is charged by an external removable induction belt worn by the patient. Delivery duration and delivery frequency may be changed before implantation of the spine pump according to the specific needs of the patient. The current device employs a mathematical model that enables the regulation as well as attenuation of the bone fusion process by extending and generalizing the model to enhance and optimize the delivery of osteogenetic agent in a regulated manner. | 04-21-2011 |
20110092950 | Metronomic Convection Enhanced Delivery of Intrathecal Chemotherapy Using an Implanted Magnetic Breather Pump (MBP) for Leptomeningeal Carcinomatosis - A magnetically controlled pump is implanted into the cerebrospinal fluid of a patient and delivers a plurality of medicating agents at a controlled rate corresponding to the specific needs of the patient. The current invention comprises a flexible double walled lumen, intratumoral catheter which will be implanted. Spinal fluid drawn from the patient is analyzed. Medication is delivered on a continuous metronomic basis into the CSF via an internalized pump. CSF is removed and analyzed for VEGF and other cytokines via spectrophotometer analysis or a lab on a chip. The operation of the apparatus and hence the treatment is remotely controlled based on these measurements and displayed through an external controller. | 04-21-2011 |
20110092960 | ENHANCED METHOD FOR DELIVERING BEVACIZUMAB (AVASTIN) INTO A BRAIN TUMOR USING AN IMPLANTED MAGNETIC BREATHER PUMP - A magnetically controlled pump is implanted into the brain of a patient and delivers a plurality of medicating agents mixed with Avastin at a controlled rate corresponding to the specific needs of the patient. The current invention comprises a flexible double walled pouch that is formed from two layers of polymer. The pouch is alternately expanded and contracting by magnetic solenoid. When contracted, the medicating agent Avastin is pushed out of the pouch through a plurality of needles. When the pouch is expanded, surrounding cerebral fluid is drawn into the space between the double walls of the pouch from which it is drawn through a catheter to an analyzer. In cases where a tumor resection is not performed, an intratumoral catheter will be implanted. Cerebral fluid drawn from the patient is analyzed. The operation of the apparatus and hence the treatment is remotely controlled based on these measurements and displayed through an external controller. | 04-21-2011 |
20120041562 | Remotely Activated Piezoelectric Pump for Delivery of Biological Agents to the Intervertebral Disc and Spine - A remotely activated piezoelectric pump for delivery of biological agents to the intervertebral disc and spine in order to achieve spinal fusion. A spinal pump is implanted on the vertebrae of a patient and a spinal cage is inserted in between two adjacent vertebrae after removal of the vertebrae disc. A piezoelectric motor drives the pump and pushes osteogenetic agent through the spinal cage and into a sponge disposed within the cage. The pump is charged by an external removable induction belt worn by the patient. Delivery duration and delivery frequency may be changed before implantation of the spine pump according to the specific needs of the patient. The current device employs a mathematical model that enables the regulation as well as attenuation of the bone fusion process by extending and generalizing the model to enhance and optimize the delivery of osteogenetic agent in a regulated manner. | 02-16-2012 |
20120245565 | METHOD FOR DELIVERING GENE AND CELL THERAPY TO A TUMOR OR TARGETED SITE USING AN IMPLANTED METRONOMIC BIOFEEDBACK PUMP - A method for utilizing a controlled pump implanted into a patient connected to a multilumen catheter allowing delivery to and sampling from the brain or other organ for treatment of a cancer. The pump delivers a plurality of medicating agents, including viral and non-viral vectors for gene therapy and cell therapy at a controlled rate, corresponding to the specific needs of the patient. A catheter is implanted in or adjacent to the tumoral region. Fluid drawn from the tumor region to the pump via the multilumen catheter is analyzed within the pump by various biofeedback sensors. The operation of the apparatus and hence the treatment is remotely controlled based on these measurements and displayed through an external controller. The method allows localized delivery of gene and cell therapy to a solid tumor or tumoral region, or to any other treatment area of interest within the patient. | 09-27-2012 |
20140295549 | METHODS AND COMPOSITIONS FOR INDUCING APOPTOSIS BY STIMULATING ER STRESS - The present invention provides a method for inducing apoptosis in selected cells by aggravating ER-stress. The aggravation of ER-stress is achieved in a specific manner by inhibiting SERCA (sarcoplasmic/endoplasmic reticulum calcium ATPase), leading to elevated level of cytoplasmic calcium concentration, yet without inhibiting the activity of COX-2 (cyclooxygenase-2) or triggering the release of histamine. Induction of apoptosis may be enhanced by first inducing or further aggravating ER-stress through inhibition of proteasome or proteases. Also provided are compounds and compositions useful as ER-stress aggravating agents, methods for screening, selecting, identifying and designing the same and methods for treating diseased conditions by inducing apoptosis through specific and selective aggravation of ER-stress. | 10-02-2014 |
Patent application number | Description | Published |
20080229578 | ROCKER ARM WITH INTEGRAL INTERNAL OIL PASSAGES - A rocker arm and method for manufacture is provided whereby the rocker arm is manufactured in two halves generally symmetric to a central plane. The mating surface of one or both rocker arm halves incorporate grooves which upon assembly provide passageways which may follow any desired pathway for lubricant and or afford a reduction in mass and/or an increase in structural stiffness. The two halves are preferably joined together by metallurgical brazing or by other chemical or mechanical means. | 09-25-2008 |
20080271693 | DEACTIVATING ROCKER ARM / MECHANICAL LASH ADJUSTMENT SYSTEM - A deactivating rocker arm mechanical adjustment system for internal combustion engines is provided wherein a lash adjustment screw which has eccentric cam and a feature by which the screw can be rotated using a tool. The adjustment screw is installed a valve actuation section of a split rocker arm wherein the cam end of the adjustment screw engages a feature of the cam follower section of the split rocker arm. When the lash adjustment screw is rotated, the design of the cam is such that the angular orientation of the valve actuation and cam follower sections is varied and in turn varies the distance or lash between the cam follower section latch pin and the receiving latch pin hole in the valve actuation section. The lash adjustment screw is rotated until a previously specified lash is obtained and then a jam nut is tightened to prevent rotation of the lash adjustment screw. Valvetrain component design may be altered that other than threaded means may be used to control the rotational orientation of the adjustment cam. An additional feature of the invention is that in the preferred embodiment, the lash adjustment screw provides a valve actuation section feature upon which a lost motion spring is mounted. | 11-06-2008 |
20080302322 | TUBULAR ROCKER SHAFT WITH MULTIPLE INTERNAL COMPARTMENTS - A rocker shaft having at least two transversely formed interior compartments is provided each of which is devised for, and capable of, containing fluid at differing pressures. A multiplicity of generally radially directed holes present along the length of the rocker shaft communicate hydraulic fluid to the compartments via passageways present in the rocker arms, or valve deactivating rocker arm sections mounted thereon. Plugs installed within the rocker shaft at locations on either side of the holes provide compartmented regions within the shaft, each region of which has the capacity to contain hydraulic fluid at different pressures. The rocker shaft is capped at each end. Hydraulic fluid may be provided to the rocker shaft interior in a number of ways, such as through additional holes aligned with passageways provided in the cylinder head or through clearance openings between rocker shaft fasteners and rocker shaft mounting holes. | 12-11-2008 |
20090173303 | HYDRAULIC LASH ADJUSTER EQUIPPED WITH AUXILIARY CHECK VALVE - An auxiliary check valve is provided in a hydraulic lash adjuster of the type wherein the plunger-to-body clearance is sealed. The auxiliary check valve is derived so that it remains open until the plunger has been moved to the limit of its travel by rotation of the engine camshaft during engine assembly. The auxiliary check valve permits fluid within the hydraulic lash adjuster high pressure chamber to be displaced to the reservoir chamber allowing the hydraulic lash adjuster to shorten from its free length to the proper installed length. | 07-09-2009 |
20100018276 | SHEET METAL ROCKER ARM WITH INTEGRALLY FORMED CROSS MEMBER - A sheet metal rocker arm of the end pivot rocker arm type formed by bending into a U shape a precursor sheet metal piece and characterized by having a reinforcing cross member which is integrally formed by bending a tab that is cut in the central portion of the connecting part of a U-channel element to yield a reinforcing cross member to provide a unitary structure that introduces substantially enhanced stiffness to the rocker arm. The method of creating integrally formed reinforcing cross-members by appropriately cutting slits that provide reinforcing members can be applied to any stamped rocker arm that has a U-channel architecture, e.g., including, for example, rocker arms for pushrod type valvetrains as well as roller finger follower type rocker arms. Provision of the integrally formed cross member abutting the inner wall of the sides of the U-shaped rocker arm renders stiffness to the rocker arm that enables an engine to operate at a higher rpm and thereby improves horsepower output. | 01-28-2010 |
Patent application number | Description | Published |
20090078910 | FUNCTIONALIZED LONG-CHAIN OLEFIN MIXTURES AND USES THEREFOR - Novel mixtures of long-chain (C10-C20) olefins are functionalized by conversion to aldehydes using an OXO process, or to sulfates, sulfonates, sulfones, sulfides, or sulfoxides by direct sulfonation. The aldehydes may then be hydrogenated to form alcohols, or aminated to form amines or amides. The olefins starting mixture may be acquired as a byproduct of the tetramerization of ethylene in the presence of certain chromium-containing tetramerization catalysts. The functionalized mixtures, and derivatives prepared therefrom such as alkoxylates prepared from the alcohols, may be useful as surfactants that may offer improved performance in many applications, while their preparation based on a byproduct mixture reduces their cost and also reduces waste-handling issues for this non-targeted stream. | 03-26-2009 |
20100069680 | HYDROFORMYLATION PROCESS WITH IMPROVED CONTROL OVER PRODUCT ISOMERS - A continuous hydroformylation process for producing a mixture of aldehydes with improved flexibility and stability of a normal/branched (N/I) isomer ratio of the product aldehydes. The process involves reacting one or more olefinically-unsaturated compounds with carbon monoxide and hydrogen in the presence of an organopolyphosphite ligand and an organomonophosphite ligand, at least one of such ligands being bonded to a transition metal to form a transition metal-ligand complex hydroformylation catalyst; the process being conducted at a sub-stoichiometric molar ratio of organopolyphosphite ligand to transition metal, at a super-stoichiometric (>2/1) molar ratio of organomonophosphite ligand to transition metal, and at a carbon monoxide partial pressure in the inverse order region of the hydroformylation rate curve; and controlling and varying the isomer ratio by varying the concentration of organopolyphosphite ligand relative to transition metal. | 03-18-2010 |
20110269997 | Process of Controlling Heavies in a Recycle Catalyst Stream - A process of controlling heavies in a recycle catalyst stream, particularly, for use in a continuous hydroformylation process of converting an olefin with synthesis gas in the presence of a hydroformylation catalyst to form an aldehyde product stream with subsequent separation of the catalyst for recycle to the hydroformylation step. Heavies are controlled, and preferably reduced, by means of feeding a recycle gas stream, taken as a portion of an over-head stream from a condenser, back to a vaporizer wherein the aldehyde product stream is separated. | 11-03-2011 |
20120253080 | Controlling the Normal:ISO Aldehyde Ratio in a Mixed Ligand Hydroformylation Process by Controlling the Olefin Partial Pressure - Control of an in-series, multiple, e.g., two, reaction zone, hydroformylation process for producing normal (N) and iso (I) aldehydes at a N:I ratio, the process comprising contacting an olefinically unsaturated compound, e.g., propylene, with carbon monoxide, hydrogen and a catalyst comprising (A) a transition metal, e.g., rhodium, (B) an organobisphosphite, and (C) an organomonophosphite ligand, the contacting conducted in first and subsequent reaction zones and at hydroformylation conditions comprising an olefinically unsaturated compound partial pressure in each zone, the control exercised by decreasing the olefinically unsaturated compound partial pressure in the first reaction zone to decrease the N:I ratio or increasing the olefinically unsaturated compound partial pressure in the first reaction zone to increase the N:I ratio. | 10-04-2012 |
20120253081 | Controlling the Normal:ISO Aldehyde Ratio in a Mixed Ligand Hydroformylation Process by Conrolling the Syngas Partial Pressure - A method of controlling a hydroformylation process for producing normal (N) and iso (I) aldehydes at a N:I ratio, the process comprising contacting an olefinically unsaturated compound, e.g., propylene, with synthesis gas and a catalyst comprising a transition metal, e.g., rhodium, and an organopolyphosphite and an organomonophosphite ligand, the contacting conducted at hydroformylation conditions comprising a synthesis gas partial pressure, the method comprising increasing the synthesis gas partial pressure in the first reaction zone to decrease the N:I ratio or decreasing the synthesis gas partial pressure in the first reaction zone to increase the N:I ratio. | 10-04-2012 |
20120259142 | Controlling the Normal:ISO Aldehyde Ratio in a Mixed Ligand Hydroformylation Process - A method of controlling an in-series, multiple, e.g., two, reaction zone, hydroformylation process for producing normal (N) and iso (I) aldehydes at a N:I ratio, the process comprising contacting an olefinically unsaturated compound with synthesis gas and a catalyst comprising (A) a transition metal, e.g., rhodium, (B) an organobisphosphite ligand, and (C) an organomonophosphite ligand, the contacting conducted in first and subsequent reaction zone(s) and at hydroformylation conditions comprising a transition metal concentration in each zone, the method comprising decreasing the transition metal concentration in the first reaction zone to decrease the N:I ratio or increasing the transition metal concentration in the first reaction zone to increase the N:I ratio. | 10-11-2012 |
20130261344 | Mitigation of Fouling in Hydroformylation Processes by Water Addition - The extraction process for removing metal salts from an organic hydroformylation reaction fluid (“HRF”) prior to returning the HRF to a reaction zone of a hydroformylation process, the extraction process comprising the step of contacting the HRF with an aqueous buffer solution, is improved by contacting the HRF with water in addition to that present in the aqueous buffer solution, i.e., with added water. | 10-03-2013 |
Patent application number | Description | Published |
20100234328 | Antimicrobial Compositions And Related Methods - A liquid antimicrobial composition comprising an organic acid and one or more anionic surfactants is disclosed. In one embodiment, the organic acid is lactic acid and the anionic surfactant is sodium octane sulfonate. In a preferred embodiment, the antimicrobial solution is formulated as a teat dip for lactating animals, particularly cows. In other embodiments, the antimicrobial compositions may be used in personal care, hard surface care including hard surface disinfection in households, food processing, hospitals, restaurants, hotels, showers, or topically as hand soaps, surgical scrubs, and hoof disease mitigators. | 09-16-2010 |
20100234460 | Compositions Comprising A C2-C14 Carboxylic Acid And A Surfactant For Treating Hoof Diseases - Germicidal compositions containing at least one carboxylic acid combined with at least one nonionic or anionic surfactant, and methods of using the compositions for treatment or prevention of infectious hoof diseases are disclosed. The germicidal compositions remain active in the presence of manure, which eliminates the need to pre-clean the hooves before use. The compositions have particular utility for treating or preventing papillomatous digital dermatitis, interdigital phlegmon, interdigital dermatitis, laminitis, white line disease, heel erosion and other hoof diseases. | 09-16-2010 |
20100286270 | Compositions For The Treatment Of Hoof Diseases - Germicidal compositions containing one or more N,N-bis(3-aminopropyl) C | 11-11-2010 |
Patent application number | Description | Published |
20100081878 | Integrated Locking Device With Active Sealing - Endoscope assemblies, biopsy caps, and methods for making and using the same. An example endoscope assembly may include an endoscope having a channel formed therein and a port that provides access to the channel. A cap may be coupled to the port. The cap may include a base and an outer shell. A locking member may be coupled to the outer shell. An inner seal member may be disposed within the outer shell. One or more openings may extend through the cap and into the channel. An actuator may be coupled to the base for shifting the inner seal member between an unsealed configuration and a sealed configuration. | 04-01-2010 |
20100087705 | Integrated Locking Device With Passive Sealing - Endoscope assemblies, biopsy caps, and methods for making and using the same. An example endoscope assembly may include an endoscope having a channel formed therein and a port that provides access to the channel. A cap may be coupled to the port. The cap may include a base having a securing member for securing the cap to the port, an outer shell, a locking member coupled to the outer shell, an inner seal member, and a central opening that extends to the channel. The inner seal member may include a plurality of flaps. | 04-08-2010 |
20100087710 | Integrated Locking Device With Fluid Control - Endoscope assemblies, biopsy caps, and methods for making and using the same. An example endoscope assembly may include an endoscope having a channel formed therein and a port that provides access to the channel. A cap may be coupled to the port. The cap may include a base having a securing member for securing the cap to the port. The cap may also include an outer shell, a locking member coupled to the outer shell, an inner seal member disposed within the outer shell, and one or more openings extending through the cap and into the channel. A fluid control region may be defined within the outer shell. | 04-08-2010 |
Patent application number | Description | Published |
20090250870 | Variant Games of Chance Using Three Dice - An apparatus and method of game play comprising three dice. Each of the three dice may be distinctly colored and further include distinct indicia thereon. Preferably, a first die may be six-sided, green in color, and bears a sequential even number (e.g. 2, 4, 6, 8, 10, and 12) on each if its respective six faces. A second die may be six-sided, yellow in color, and bear a sequential number (e.g. 1, 2, 3, 4, 5, and 6) on each if its respective six faces. A third die may be six-sided, red in color, and bear a sequential odd number (e.g. 1, 3, 5, 7, 9, and 11) on each if its respective six faces. Such three dice may be incorporated into short play dice games, long play dice games, casino table games, board games, and the like. | 10-08-2009 |
Patent application number | Description | Published |
20100155132 | MONOMOLECULAR CARBON-BASED FILM FOR ENHANCING ELECTRICAL POWER TRANSMISSION - Power cable shields having a monomolecular carbon-based film are placed around electrical power lines to reduce power losses and enhance transmission of electricity. The shield may be a solid metal tube or a material wrapped around a power cable. The monomolecular carbon-based film is deposited on the shield, for example, using a reactor that includes a bed of silica coupled to a diesel engine to produce a stream of dehydrated hydroxyl radicals that become hydrated due to reactions of supercritical water and muon methyl radicals. A shielded electrical power includes a shield positioned around and fully enclosing the power line to prevent atmospheric loss of electrical power. An existing power line can be retrofitted by placing one or more surface treated sleeves around the existing power line. Periodically spaced apart magnets can be positioned within the electrical wire shield to further boost power and voltage through the electrical power line. | 06-24-2010 |
20100155524 | MONOMOLECULAR CARBON-BASED FILM FOR FORMING LUBRICIOUS SURFACE ON AIRCRAFT PARTS - A monomolecular carbon-based film can be placed on an aircraft part, such as the leading edge designed to directly impinge against air during flight, ascent or descent, in order to form a smooth surface having increased lubricity and reduced air friction. The aircraft part may be in the form of a helicopter rotor, wing, propeller, fin, aileron, nose cone, and the like. The monomolecular carbon-based film can be deposited on the aircraft part, for example, using a reactor that includes a bed of silica and through which emissions from a diesel engine are passed. The monomolecular carbon-based film decreases air friction and increased lift of a modified aircraft that includes an aircraft part treated with the film. It also provides a structured shock absorber. | 06-24-2010 |
20100155527 | MONOMOLECULAR CARBON-BASED FILM FOR FORMING LUBRICIOUS SURFACE ON AIRCRAFT PARTS - A monomolecular carbon-based film can be placed on an aircraft part, such as the leading edge designed to directly impinge against air during flight, ascent or descent, in order to form a smooth surface having increased lubricity and reduced air friction. The aircraft part may be in the form of a helicopter rotor, wing, propeller, fin, aileron, nose cone, and the like. The monomolecular carbon-based film can be deposited on the aircraft part, for example, using a reactor that includes a bed of silica and through which emissions from a diesel engine are passed. The monomolecular carbon-based film decreases air friction and increased lift of a modified aircraft that includes an aircraft part treated with the film. | 06-24-2010 |
20100219805 | APPARATUS AND METHODS FOR BOOSTING ELECTRICAL POWER - An electrical power boosting apparatus includes a metal substrate having a monomolecular carbon-based film on first and second surfaces, a conductive core, a positive electrode at one end, and a negative electrode an opposite end and magnets positioned adjacent and in a spaced-apart relationship to the metal substrate, the magnets are oriented so that north and south poles of each magnet are matched with opposite poles of an adjacent magnet. Electrical power is boosted by passing an initial electric current having an initial voltage through the conductive core of the metal substrate and causing or allowing an interaction between the metal substrate, the monomolecular carbon-based film, and the magnets to produce a modified electric current having a final voltage that is greater than the initial voltage. | 09-02-2010 |
20130086905 | METHOD AND SYSTEM FOR ENHANCED ENERGY PRODUCTION FROM TRANSFORMING, REDUCING AND ELIMINATING ORGANIC MATERIAL AND MEDICAL WASTE - A waste transformation and destruction apparatus includes a natural gas ignition system, a silica material bed, a heat transfer device, and a system for collecting plasma produced energy. A reaction formed by heat from ignition, carbon from the waste material, supercritical water, —OH radicals, and muons released from the silica bed transform the waste into a fuel. This fuel is more efficiently consumed by the complete combustion process resulting in near total elimination of the waste, increased energy production, and virtually no emissions. | 04-11-2013 |
Patent application number | Description | Published |
20090257901 | POWER STEERING PUMP HAVING INTAKE CHANNELS WITH ENHANCED FLOW CHARACTERISTICS AND/OR A PRESSURE BALANCING FLUID COMMUNICATION CHANNEL - A power steering pump having a plate disposed between a first surface and an intake chamber, wherein an intake flow channel defined by the first surface is in fluid communication with the intake chamber through an opening extending through the plate, the plate opening having opposed terminal ends. The intake flow channel defined by the first surface is configured to direct fluid flow through the plate opening into the intake chamber at a location through the plate opening that is intermediate and spaced from the two terminal ends of the plate opening. Also, a power steering pump having a plate disposed between a first surface and a pair of intake chambers, wherein a pair of intake flow channels defined by the first surface are in fluid communication with the intake chambers through a corresponding pair of openings extending through the plate. A pressure balancing fluid communication channel extends between the pair of intake flow channels to provide fluid communication between areas of the two intake flow channels where each intake flow channel is in communication with an opening extending through the plate, the pressure balancing fluid channel tending to equalize the fluid pressure in the two intake flow channels at the areas where they communicate with the plate openings. | 10-15-2009 |
20130089456 | Cartridge Style Binary Vane Pump - A binary vane pump is provided. The binary vane pump includes a pressure plate having a first discharge port, a thrust plate having a second discharge port, a ring positioned axially between the pressure plate and thrust plate, the ring having an inner cam surface, and a rotor rotatably disposed within the ring, the rotor having a plurality of slots and a plurality of vanes, vanes of the plurality vanes corresponding to respective slots of the plurality of slots and radially movable with the respective slots. A first and second pump chamber are disposed within the ring, separated by the rotor, vanes, pressure plate and thrust plate, the first pump chamber configured to discharge fluid to the first discharge port and the second pump chamber configured to discharge fluid to the second discharge port. A shaft extends through the pressure plate, thrust plate, ring and rotor and drives the rotor. | 04-11-2013 |
20140271299 | HYDRAULICALLY BALANCED STEPWISE VARIABLE DISPLACEMENT VANE PUMP - A binary vane pump providing a balanced, stepwise variable displacement is provided. The binary vane pump includes a pressure plate having first and second discharge ports configured to discharge fluid from the binary vane pump to a first discharge path and a thrust plate having third and fourth discharge ports configured to discharge fluid from the binary vane pump to a second discharge path. The binary vane pump also includes a ring positioned axially between the pressure plate and thrust plate, the ring having an inner cam surface, a rotor rotatably disposed within the ring, the rotor having a plurality of slots and a plurality of vanes received and movable within respective slots, and a shaft extending along an axis through the rotor and configured to rotate the rotor so that the vanes are rotatable within the ring. | 09-18-2014 |
Patent application number | Description | Published |
20110045443 | METHODS FOR USING DENTAL COMPOSITIONS CONTAINING FLUORESCENT AGENTS - A method of applying a dental composition to tooth surfaces is provided. The dental composition, comprising polymerizable resin and fluorescing compound, is applied to a tooth surface and cured so that it hardens. The composition is preferably used as a dental sealant that provides a hard, glossy surface finish over a tooth. Upon irradiating the sealant with ultraviolet light, the sealant exhibits a bright fluorescent glow. The sealant reverts immediately to its natural color when it is no longer exposed to the ultraviolet light. | 02-24-2011 |
20120028223 | METHODS FOR USING DENTAL COMPOSITIONS CONTAINING FLUORESCENT AGENTS - A method of applying a dental composition to tooth surfaces is provided. The dental composition, comprising polymerizable resin and fluorescing compound, is applied to a tooth surface and cured so that it hardens. The composition is preferably used as a dental sealant that provides a hard, glossy surface finish over a tooth. Upon irradiating the sealant with ultraviolet light, the sealant exhibits a bright fluorescent glow. The sealant reverts immediately to its natural color when it is no longer exposed to the ultraviolet light. | 02-02-2012 |
20140248222 | DENTAL VARNISH COMPOSITIONS - Disclosed herein are substantially transparent and colorless dental varnishes having improved fluoride release, transparency and color once coated. | 09-04-2014 |
Patent application number | Description | Published |
20090287423 | MAGNETIC FLUX TAGGING FOR QUALITY CONSTRUCTION - A system and a method for monitoring a building material are disclosed. The system and the method provide a comprehensive monitoring throughout a manufacturing and an application process and provide a real time data feedback relating to the physical characteristics of the building material. The system and method include mixing a predetermined amount of taggant particles with a predetermined volume of at least one component of the building material in order to comprehensively monitor a mix ratio and segregation of the building material during manufacturing and application. | 11-19-2009 |
20110138887 | INSPECTION OF INSTALLED ASPHALT - An apparatus and a method for monitoring a ratio of at least two mixed components use a sensor for detecting taggant particles in one of the components of the mixed material after installation. The sensor is positioned adjacent a surface of the installed mixture and is connected to a control device for displaying an indication of a mixture ratio of the components below the surface. The control device also generates a profile of the mixture ratio of the installed mixed material versus a distance from the surface. | 06-16-2011 |
20110140889 | INSPECTION OF ASPHALT DURING INSTALLATION - An apparatus and a method for monitoring a ratio of at least two components being mixed use sensors detecting ferrous taggant particles in the component(s) and the mixture. The sensors include an annular drive coil positioned between inner and outer annular sense coils all surrounding a passage for material being sensed. The ratio is determined by comparing a signal generated by one sensor through which a taggant particle containing component is flowing with a signal generated by another sensor through which the mixture is flowing delayed by the time required for the component to flow from the one sensor to the another sensor. The signals can also be used to control the flow of the components and to check the mixture after use for such mixtures as asphalt and concrete. | 06-16-2011 |
20120216606 | INSPECTION OF INSTALLED/MANUFACTURED MATERIAL - An apparatus and a method for monitoring a ratio of at least two mixed components use a sensor for detecting taggant particles in one of the components of the mixed material after installation. The sensor is positioned adjacent a surface of the installed mixture and is connected to a control device for displaying an indication of a mixture ratio of the components below the surface. The control device also generates a profile of the mixture ratio of the installed mixed material versus a distance from the surface. | 08-30-2012 |
20130055789 | METHOD AND APPARATUS FOR SENSING MAGNETIC RADIATION THROUGH TAGGING - A method and an apparatus for monitoring a material includes adding tagging particles to the material, sensing the tagging particles in the material for an even distribution throughout the material, forming a part from the material if the tagging particles are evenly distributed throughout the material, sensing the tagging particles in the part to determine a physical characteristic of the part, placing the part in operation if the determined physical characteristic is within a predetermined specification, sensing the tagging particles in the part during operation to detect at least one of wear and damage to the part, and generating an indication to a user upon detection of the at least one of wear or damage to the part. | 03-07-2013 |
Patent application number | Description | Published |
20080227663 | SYSTEMS AND METHODS FOR HIGH SPEED ARRAY PRINTING AND HYBRIDIZATION - Novel and improved systems and methods for high speed arraying, hybridization, quantitative development and/or assaying are provided. Some embodiments provide a web based arraying format. Some other embodiments provide a sheet based arraying format. Some embodiments use a drop on drop assaying or hybridization mode. In some embodiments, a substantially inert substrate is utilized. In some other embodiments, an interactive substrate is utilized. | 09-18-2008 |
20120184462 | LATERAL FLOW ASSAYS USING TWO DIMENSIONAL FEATURES - The present invention relates to novel lateral flow devices using two dimensional features, preferably, uniform two dimensional test and control features, and the methods for detecting an analyte using the lateral flow devices, and processes for making the lateral flow devices. | 07-19-2012 |
20130225448 | LATERAL FLOW ASSAYS USING TWO DIMENSIONAL FEATURES - The present invention relates to novel lateral flow devices using two dimensional features, preferably, uniform two dimensional test and control features, and the methods for detecting an analyte using the lateral flow devices, and processes for making the lateral flow devices. | 08-29-2013 |
20130225449 | LATERAL FLOW ASSAYS USING TWO DIMENSIONAL FEATURES - The present invention relates to novel lateral flow devices using two dimensional features, preferably, uniform two dimensional test and control features, and the methods for detecting an analyte using the lateral flow devices, and processes for making the lateral flow devices. | 08-29-2013 |
20140024016 | LATERAL FLOW ASSAYS USING TWO DIMENSIONAL FEATURES - The present invention relates to novel lateral flow devices using two dimensional features, preferably, uniform two dimensional test and control features, to provide flow control information, to function as an internal control and/or to provide internal calibration information for the test device. The present invention also relates to methods for using the lateral flow devices to provide flow control information, to function as an internal control and/or to provide internal calibration information for the test device. | 01-23-2014 |
20150080254 | LATERAL FLOW ASSAYS USING TWO DIMENSIONAL TEST AND CONTROL SIGNAL READOUT PATTERNS - The present invention relates to novel lateral flow devices using two dimensional features, preferably, uniform two dimensional test and control signal readout patterns, and the methods for detecting an analyte using the lateral flow devices. | 03-19-2015 |
Patent application number | Description | Published |
20090126731 | PATIENT INTERFACE ASSEMBLY FOR RESPIRATORY THERAPY - A patient interface assembly includes a housing that defines an inlet port and an outlet port. A jet pump receives pressurized gas flow from the inlet port and delivers the gas flow to the outlet port. A nebulizer is fluidly coupled to the outlet port and positioned to introduce medication into the gas flow and deliver medicated gas flow to a patient. | 05-21-2009 |
20100307487 | RESPIRATORY THERAPY DEVICE AND METHOD - A respiratory therapy device including a housing and an interrupter valve assembly. The housing includes a patient inlet, an exhaust outlet, a chamber, and a supply inlet. The interrupter valve assembly is associated with the housing and includes a control port fluidly connecting the patient inlet and the first chamber, and a valve body adapted to selectively obstruct fluid flow through the control port. In a passive mode, positive fluid flow to the supply inlet does not occur, and the interrupter valve assembly interacts with exhaled air create an oscillatory PEP effect. In an active mode, fluid flow to the supply inlet occurs and the interrupter valve assembly operates to create a CHFO effect. The respiratory device can serve as a passive oscillatory PEP device, and when connected to a positive pressure source, as an active device. | 12-09-2010 |
20120012112 | RESPIRATORY THERAPY DEVICE - A respiratory therapy device including a housing and an interrupter valve assembly. The housing is sized for handling by a patient and defines a patient breathing passage extending from a patient end and through which a patient inhales and exhales air. The interrupter valve assembly is carried by the housing and includes a control port, a valve body, and a drive mechanism. Expiratory airflow is released from the patient breathing passage through the control port. The valve body is sized to at least partially obstruct fluid flow through the control port. The drive mechanism moves the valve body relative to the control port in response to the expiratory airflow such that the valve body repeatedly transitions between a position of maximum obstruction and a position of minimum obstruction relative to the control port to create an oscillatory positive expiratory pressure effect. | 01-19-2012 |
Patent application number | Description | Published |
20110075956 | Sleeve for Oil Film Bearing - A sleeve is disclosed for use in an oil film bearing of the type employed to rotatably support the tapered neck of a roll in a rolling mill. The sleeve is machined from a hollow forging of a base metal with a cylindrical outer surface and a tapered inner surface adapted to be seated on the tapered roll neck. The tapered inner surface of the sleeve is coated with a layer of material that is chemically dissimilar with respect to the base metal. | 03-31-2011 |
20110108652 | ROLLING MILL LAYING HEAD - A rolling mill laying head comprises a quill rotatable about a central axis. A guide pipe carried by the quill and is configured and arranged to form a longitudinally moving product into a continuous series of rings. Axially spaced bearings support the quill on a stationary support structure for rotation about its axis. At least one of the bearings comprises a hydrostatic oil film bearing. | 05-12-2011 |
20110274380 | SELF PUMPING OIL FILM BEARING - A system is disclosed for use in a rolling mill oil film bearing to remove a laminar flow of oil exiting tangentially from between a rotating sleeve and a fixed bushing surrounding the sleeve. The system comprises confinement surfaces cooperating with the sleeve and the bushing to define an annular chamber arranged to receive the exiting laminar flow of oil. Impellers project into the chamber and are rotatable with and at the velocity of the sleeve to thereby propel the oil around the annular chamber. An outlet communicates tangentially with the annular chamber for removing oil being propelled around the chamber by the rotation of the impellers. The size of the outlet in relation to the volume of oil received in the annular chamber is such that the chamber remains filled with oil during steady state operation of the bearing. | 11-10-2011 |
20110278801 | NECK SEAL - A seal is disclosed for use in a rolling mill oil film bearing in which a sleeve is mounted on a roll neck for rotation therewith, the sleeve is journalled for rotation in a fixed bushing, and a flow of oil exits from between the sleeve and the bushing. The seal comprises a flexible circular seal body adapted to be mounted on and to rotate with the roll neck. Circumferentially spaced impellers project from the seal body. The impellers are rotatable with the seal body and serve to rotatively propel oil exiting from between the sleeve and bushing. | 11-17-2011 |
20110299801 | VENTURI DRAIN FOR SELF-PUMPING BEARING ROLLING MILLS - A system is disclosed for use in a rolling mill oil film bearing to remove oil exiting from between a rotating sleeve and a fixed bushing surrounding the sleeve. The system comprises an annular chamber arranged to receive the exiting flow of oil. The chamber is isolated from a drainage sump by confinement surfaces including a seal interface defined by a flexible seal in contact with an adjacent rigid component of the bearing. Impellers project into the chamber and are rotable with and at the velocity of the sleeve to rotatively propel oil around the chamber. A discharge conduit communicates tangentially with the chamber and is arranged to receive a pressurized flow of the oil being rotatively propelled around the chamber. A venturi is located in the discharge conduit. A suction conduit connects the venturi to the drainage sump. Oil escaping from the annular chamber past the seal interface into the drainage sump is aspirated by the venturi for removal via the conduit. | 12-08-2011 |
20120301063 | SELF ALIGNING OIL FILM BEARING - An oil film bearing for rotatably supporting a shaft comprises a spherical housing having a bore in which the shaft is rotatably supported, and an outer spherical surface. A chock contains the spherical housing. The chock is internally configured with an inner spherical surface coacting with the outer spherical surface of the spherical housing to define a raceway configured to accommodate angular rotation of the shaft about a central point. | 11-29-2012 |
20130081438 | HYBRID HYDRODYNAMIC AND HYDROSTATIC BEARING BUSHING AND LUBRICATION SYSTEM FOR ROLLING MILL - Rolling mill bearings incorporate bearing bushings with pluralities of hydrostatic pad recesses, that are preferably in conjunction hydrodynamic bearings also formed within the bushing. Each recess has an isolated lubricant passage that is adapted for coupling to a separate isolated source of pressurized lubricant. In some embodiments herein, the isolated pressurized lubricant source is supplied by a dedicated outlet of a pressure pump. In this manner each hydrostatic pad recess has a dedicated pressurized lubricant supply that is not interrupted by loss of lubricant pressure events in other bearing pads or elsewhere within the rolling mill lubrication system. | 04-04-2013 |
20140374526 | ROLLING MILL LAYING HEAD - Aspects of the present invention relate to a rolling mill laying head. The rolling mill laying head comprises a quill rotatable about a central axis, said quill being equipped with a guide pathway configured and arranged to form a longitudinally moving product into a continuous series of rings; a stationary support structure; and axially spaced radial bearings supporting said quill for rotation about said axis, one of said bearings comprising a hydrostatic oil film bearing having an internal diameter of at least about 500 mm, and having a L/D ratio less than 0.25. | 12-25-2014 |
Patent application number | Description | Published |
20090020379 | Low Mass Multi-Piece Sound Dampened Article - A multi-piece sound dampened brake rotor comprises a relatively light weight hub with a hub flange and a heavier rotor body with a sound damping insert and a rotor body flange. The hub and rotor body are attached at their flanges. The flanges may be mechanically attached such as with bolts. Or the hub and rotor may be attached by casting the hub of a lower melting metal alloy against the rotor body and rotor body flange. The rotor body may have vanes for air cooling and a sound damping insert may be incased in either or both body portions sandwiching the vanes. | 01-22-2009 |
20090020383 | DAMPED PART - A part including a body including a metal, and a frictional damping means, the frictional damping means comprising frictional surfaces in local contact but not bonded together, or the frictional damping means including a layer including at least one of particles, flakes, or fibers, the layer having a thickness ranging from about 1 μm to about 500 μm. | 01-22-2009 |
20090022938 | METHOD OF MANUFACTURING A DAMPED PART - One embodiment includes a damped product including a first portion, a second portion, a first cavity formed in one of the first portion or the second portion, and a frictional damping insert at least partially received in the first cavity so that the first portion and the second portion completely enclose the frictional damping insert and so that vibration of the product is damped by the insert. | 01-22-2009 |