Graeme Cameron Murray Smith
Graeme Cameron Murray Smith, Cambridgeshire GB
Patent application number | Description | Published |
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20100240645 | COMBINATION OF CHECKPONIT KINASE (CHK) AND TELANGIECTASIA MUTATED (ATM) INHIBITORS FOR THE TREATMENT OF CANCER - A combination, comprising a checkpoint kinase (CHK) inhibitor, or a pharmaceutically acceptable salt thereof, and an ataxia telangiectasia mutated (ATM) inhibitor, or a pharmaceutically acceptable salt thereof is described. | 09-23-2010 |
20100249112 | COMBINATION OF CHK AND PARP INHIBITORS FOR THE TREATMENT OF CANCERS - A combination, comprising a checkpoint kinase (CHK) inhibitor, or a pharmaceutically acceptable salt thereof, and a poly (ADP-ribose)polymerase (PARP) inhibitor, or a pharmaceutically acceptable salt thereof is described. | 09-30-2010 |
Graeme Cameron Murray Smith, Cambridge GB
Patent application number | Description | Published |
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20080242664 | DNA-PK INHIBITORS - A compound of formula I: | 10-02-2008 |
20090023727 | PHTHALAZINONE DERIVATIVES - A compound of the formula (I): | 01-22-2009 |
20090035394 | USE OF DNA-PK INHIBITION TO SENSITISE ATM DEFICIENT CANCERS TO DNA-DAMAGING CANCER THERAPIES - This invention relates to the finding that inhibition of the catalytic subunit of DNA protein kinase (DNA-PKcs) increases the sensitivity of cancer cells that display an ATM deficient phenotype to DNA damaging therapies, such as irradiation or chemotherapy. Methods of treating cancers displaying an ATM deficient phenotype and methods of determining the susceptibility of a patient to such methods are provided. | 02-05-2009 |
20090043091 | ATM INHIBITORS - A compound of formula I: | 02-12-2009 |
20090069303 | PHTHALAZINONE DERIVATIVES - A compound of the formula (I): | 03-12-2009 |
20090163477 | PHTHALAZINONE DERIVATIVES - A compound of formula (I): | 06-25-2009 |
20100130473 | COMPOUNDS - Compounds of formula (I): A-B—C and isomers, salts, solvates, chemically protected forms, and prodrugs thereof wherein: B is selected from the group consisting of formula (i) where R | 05-27-2010 |
20110124638 | Pyrido-, Pyrazo- and Pyrimido-Pyrimidine Derivatives as mTOR Inhibitors - There is provided a compound of formula I: | 05-26-2011 |
Graeme Cameron Murray Smith, Macclesfield GB
Patent application number | Description | Published |
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20120142673 | Pyrido-, Pyrazo- and Pyrimido-Pyrimidine Derivatives as mTOR Inhibitors - There is provided a compound of formula I: | 06-07-2012 |
20140135315 | Pyrido-, Pyrazo- and Pyrimido-Pyrimidine Derivatives as mTOR Inhibitors - There is provided a compound of formula I: | 05-15-2014 |