Nicolosi
Donata Rosaria Maria Nicolosi, Catania IT
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20100148164 | ALL-ORGANIC SENSOR/ACTUATOR SYSTEM - A sensor and/or actuator system in which functional circuitry is embedded in an all organic electromechanical transducer device is disclosed. The electromechanical transducer device exploits the behavior of a flexible sensible ionomeric material sheet as effective sensing or actuating member sandwiched between flexible organic electrodes when undergoing a deformation or being polarized at a certain drive voltage applied to the, electrodes, respectively. The completely embedded all organic system is realized with a process exploiting relatively low cost deposition and patterning techniques. The enhanced flexibility makes the all organic device suitable for new applications in fields ranging from biomedical to aerospace industry. | 06-17-2010 |
Giovanni Nicolosi, Codogno (lodi) IT
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20140246155 | DOUBLE GLAZING SYSTEM - A double glazing system, including a first sheet of glass, a second sheet of glass, a spacer element including a first surface for coupling with the first sheet of glass and a second surface for coupling with the second sheet of glass, a blind, or a screen, said spacer element made from low thermally conductive material including rubber and/or silicone foam. The spacer element includes support means including a housing made of a substantially âTâ-shaped groove made on a surface perpendicular to the first surface and to the second surface. The support means include two lateral sections for guiding said blind, screen or the like having respective substantially âTâ-shaped portions and being able to be engaged in said housing, the lateral sections including respective free ends for supporting respective end portions of said blind, screen or the like. | 09-04-2014 |
Giovanni Nicolosi, Dresano (mi) IT
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20130025799 | GLASS-ENCLOSED CHAMBER AND INTERNAL VENETIAN BLIND HAVING SLATS OF IMPROVED REFLECTANCE AND DIFFUSIVITY OVER A WIDER SPECTRAL INTERVAL OF INCIDENT SOLAR RADIATION - Inside a glass-enclosed chamber is a Venetian blind connected to internal elements for operating it, the elements being workable from outside to raise, lower and incline the slats. The raw slats of the blind are obtained by moulding a rolled strip of aluminium alloy hardened by magnesium. The strip has not been lapped in order to maintain a degree of roughness on both surfaces, ready to receive a reflecting layer. Reflective stratification includes a layer of pure aluminium adherent to the body of the slat that serves to fix a reflective type of interferential dielectric multilayer. Average thickness of the layer of sputtered aluminium depends on the diffusivity of reflected radiation required in relation to the maximum height of the peaks of surface roughness on the body of the slats. Useful multilayers increase reflectance to levels averaging over 85% on a wide interval of wavelengths from near infrared to ultraviolet. | 01-31-2013 |
20150197983 | DEVICE FOR CONTROLLING THE ACTUATION OF A GROUP FOR MOVING A CURTAIN/AWNING - A device for actuating a curtain/awning in a double glazing includes a pulley supported by support elements connected to connection elements integrally connected to a wall of the double glazing at the movement group. A ring of cord is partially wound around the pulley and is maintained taught by a tensioning element, it too connected to the wall of the double glazing. By applying a tension to the cord ring, a torque is generated tending to rotate the pulley. The torque is transmitted by suitable transmission elements to the group for moving the curtain/awning. The support elements of the pulley are separated from the connection elements for values of tension applied to the cord ring that are greater than a pre-established limit value. The separation cancels the tension of the cord. | 07-16-2015 |
Giovanni Nicolosi, Catania IT
Giovanni Nicolosi, Codogno IT
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20150292258 | Spacer Profile for a Spacer Frame for an Insulating Glass Unit with Interspace Elements and Insulating Glass Unit - A spacer profile for an insulating glazing unit for maintaining a space between glazing panes includes a profile body formed from a first heat insulating material that has, viewed in a cross section perpendicular to a longitudinal direction, outer side walls extending in a height direction and that has a distance in a transverse direction smaller than a first width, each side wall having an inner protrusion protruding towards the opposite side wall into a recess which is open to the inner side, and a diffusion barrier film made from a second material and firmly bonded with the profile body and, viewed in the cross section perpendicular to the longitudinal direction, extending over the profile body on the outer side of the spacer profile and continuous thereto in the height direction on the outside of the side walls and/or in the same to a second height and into the protrusions. | 10-15-2015 |
Joseph A. Nicolosi, Alford, MA US
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20110013744 | Optical Positioner Design in X-Ray Analyzer for Coaxial Micro-Viewing and Analysis - An X-ray analyzer includes a sample stage for holding and positioning a sample and an optical positioner assembly configured above the sample stage. The optical positioner assembly includes a body member having an opening; an optical positioner located within the opening; and at least one X-ray optic and an optical viewing lens coupled to a first camera. The at least one X-ray optic and the optical viewing lens are secured to the optical positioner. The optical positioner is configured to align one of the at least one X-ray optic and the optic viewing lens normal to the sample on the sample stage such that the sample is irradiated with X-rays through the X-ray optic along a path which is normal to the sample and coaxial with the optic viewing lens receiving light reflected from the sample when the optic viewing lens is positioned normal to the sample. | 01-20-2011 |
20130341506 | Method and Apparatus for Electron Pattern Imaging - A system for electron pattern imaging includes: a device for converting electron patterns into visible light provided to receive an electron backscatter diffraction (EBSD) pattern from a sample and convert the EBSD pattern to a corresponding light pattern; a first optical system positioned downstream from the device for converting electron patterns into visible light for focusing the light pattern produced by the device for converting electron patterns into visible light; a camera positioned downstream from the first optical system for obtaining an image of the light pattern; an image intensifier positioned between the device for converting electron patterns into visible light and the camera for amplifying the light pattern produced by the device for converting electron patterns into visible light; and a device positioned within the system for protecting the image intensifier from harmful light. | 12-26-2013 |
Piergiorgio Nicolosi, Padova IT
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20090218504 | RADIOMETER WITH SPECTRAL RESPONSE EQUIVALENT TO THE ERYTHEMA ACTION CURVE CIE, FOR MEASURING THE TOTAL EFFECTIVE IRRADIANCE - A radiometer for measuring the total effective UV radiance of the type comprising, in an optical pathway sequence, a diffuser, an interference filter and a detector. Said interference filter comprises a plurality of alternating layers of magnesium fluoride and zirconium oxide, where the diffuser/interference filter/detector system has a spectral response equivalent to the erythema action curve CIE. | 09-03-2009 |
Piergiorgio Nicolosi, Legnaro IT
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20100239822 | APERIODIC MULTILAYER STRUCTURES - An aperiodic multilayer structure ( | 09-23-2010 |
Ramona C. Nicolosi, Portsmouth, NH US
Robert Nicolosi, Nashua, NH US
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20080274195 | Compositions and Methods for Making and Using Nanoemulsions - The present invention discloses an improved nanoemulsion comprising a uniform and discrete range of very small particle nano-sized diameters. This uniformity results in improved bioavailability of incorporated compounds (i.e., pharmaceuticals or nutraceuticals) as reflected in various pharmacokinetic parameters including, but not limited to, decreased T | 11-06-2008 |
20090306198 | Anti-Oxidant Synergy Formulation Nanoemulsions to Treat Caner - A uniform microfluidized nanoemulsion is disclosed containing a synergistic combination of two antioxidants and a cell membrane stabilizer phospholipid (i.e., an anti-oxidant synergy formulation; ASF). The microfluidized nanoemulsion improves the combination's cell membrane permeability by at least four-fold over conventional nanoemulsion compositions, which significantly increases the intracellular concentration of typically cell-impermeant antioxidants (i.e., for example, tocopherol) and/or systemic bioavailability. As a nanoemulsion, synergistic combination has greater anticancer efficacy than the same combination applied as a free solution. | 12-10-2009 |
20100183726 | COMPOSITIONS AND METHODS FOR TREATING CANCER WITH DACARBAZINE NANOEMULSIONS - A uniform microfluidized nanoemulsion is disclosed containing an anti-cancer agent, such as dacarbazine. The microfluidized nanoemulsion improves the combination's cell membrane permeability by at least four-fold over conventional nanoemulsion compositions, which significantly increases the intracellular concentration of anti-cancer agents. As a nanoemulsion, dacarbazine has a greater anti-cancer efficacy than when applied as a free solution. | 07-22-2010 |
20120164182 | Botulinum nanoemulsions - The embodiment described herein are related nanoemulsions comprising botulinum toxins. In one embodiment, the nanoemulsions are prepared by high pressure microfluidization and comprise a particle size distribution exclusively between 10 and 300 nm. The nanoemulsions contemplated by the present invention are useful for the cosmetic and medical treatment of muscular contracture states. For example, botulinum toxin may relax facial muscles such that skin wrinkles become smoother and less noticeable. Further, the present invention contemplates a cosmetic formulation that may be self-administered, for example, in the privacy of one's home and without medical supervision. | 06-28-2012 |
20140099342 | BOTULINUM NANOEMULSIONS - The embodiment described herein are related nanoemulsions comprising | 04-10-2014 |
20150079176 | ANTI-OXIDANT SYNERGY FORMULATION NANOEMULSIONS TO TREAT CANCER - A uniform microfluidized nanoemulsion is disclosed containing a synergistic combination of two antioxidants and a cell membrane stabilizer phospholipid (i.e., an anti-oxidant synergy formulation; ASF). The microfluidized nanoemulsion improves the combination's cell membrane permeability by at least four-fold over conventional nanoemulsion compositions, which significantly increases the intracellular concentration of typically cell-impermeant antixoidants (i.e., for example, tocopherol) and/or systemic bioavailability. As a nanoemulsion, synergistic combination has greater anticancer efficacy than the same combination applied as a free solution. | 03-19-2015 |
Robert J. Nicolosi, Nashua, NH US
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20110020227 | POLYSACCHARIDE-CONTAINING BLOCK COPOLMER PARTICLES AND USES THEREOF - The invention relates to new amphiphilic linear block copolymers of polysaccharides and polymers. The amphiphilic linear block copolymers do not form a true solution in water and are able to form micelles in selective solvents. Also disclosed are particles, each of which has a shell and a core, and a diameter of about 1 to 1,000 nanometers, and methods of delivering agents or removing substances, e.g., undesirable substances, from a subject or environment, by using these particles. | 01-27-2011 |
20110206739 | COMPOSITIONS AND METHODS FOR THE PREPARATION OF NANOEMULSIONS - The disclosure relates to compositions and methods of forming nanoemulsions, e.g., containing an active component, in combination with lipophilic components such as oils, hydrophilic components such as water, and one or more surfactants capable of causing a temperature-dependent phase inversion, such as a nonionic polyethoxylated surfactant. Nanoemulsions containing the active component can be produced having average oil droplet sizes of less than 100 nm, 50 nm, or 25 nm without the need for high energy emulsion forming methods (such as microfluidization) by combining the surfactant and the oil in specified weight ratios (e.g., at least 3:1) prior to forming the nanoemulsion. | 08-25-2011 |
20120252750 | FORMULATIONS FOR REDUCING NEURONAL DEGENERATION - Nutriceutical and pharmaceutical formulations for treating neurodegenerative disorders such as Alzheimer's disease are provided. Nutriceutical formulations include two or more of folate, vitamin E, and acetyl-L-carnitine (ALCAR). Pharmaceutical formulations include two or more of 3-deaza-adenosine (DZA), N-acetyl-L-cysteine (NAC), and S-adenosylmethionine (SAM). | 10-04-2012 |
20140017331 | POLYSACCHARIDE-CONTAINING BLOCK COPOLYMER PARTICLES AND USES THEREOF - The invention relates to new amphiphilic linear block copolymers of polysaccharides and polymers. The amphiphilic linear block copolymers do not form a true solution in water and are able to form micelles in selective solvents. Also disclosed are particles, each of which has a shell and a core, and a diameter of about 1 to 1,000 nanometers, and methods of delivering agents or removing substances, e.g., undesirable substances, from a subject or environment, by using these particles. | 01-16-2014 |
20140294964 | COMPOSITIONS AND METHODS FOR TREATING CANCER WITH DACARBAZINE NANOEMULSIONS - A uniform microfluidized nanoemulsion is disclosed containing an anti-cancer agent, such as dacarbazine. The microfluidized nanoemulsion improves the combination's cell membrane permeability by at least four-fold over conventional nanoemulsion compositions, which significantly increases the intracellular concentration of anticancer agents. As a nanoemulsion, dacarbazine has a greater anti-cancer efficacy than when applied as a free solution. | 10-02-2014 |
Robert J. Nicolosi, Tyngsborough, MA US
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20100040883 | POLYSACCHARIDE-CONTAINING BLOCK COPOLYMER PARTICLES AND USES THEREOF - The invention relates to new amphiphilic linear block copolymers of polysaccharides and polymers. The amphiphilic linear block copolymers do not form a true solution in water and are able to form micelles in selective solvents. Also disclosed are particles, each of which has a shell and a core, and a diameter of about 1 to 1,000 nanometers, and methods of delivering agents or removing substances, e.g., undesirable substances, from a subject or environment, by using these particles. | 02-18-2010 |
Robert James Nicolosi, Nashua, NH US
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20150335574 | COMPOSITIONS AND METHODS FOR MAKING AND USING NANOEMULSIONS - The present invention discloses an improved nanoemulsion comprising a uniform and discrete range of very small particle nano-sized diameters. This uniformity results in improved bioavailability of incorporated compounds (i.e., pharmaceuticals or nutraceuticals) as reflected in various pharmacokinetic parameters including, but not limited to, decreased Tmax, increased CmaX3 and increased AUC. The improved method of making these uniform nanoemulsions utilizes microfluidization which differs in both process and mechanics when compared to conventional milling and grinding techniques used to generate nanoparticulate compositions. Further, the improvement results, in part, from a novel step of mixing a substantially soluble compound into a heated dispersion medium. This is unlike current nanoparticulate composition methods that mix an insoluble compound with an unheated dispersion medium. Further, these nanoemulsions are observed to be bacterial-resistant and stable to extremes in both temperature and pH changes. Consequently, these nanoemulsions are expected to have a significantly prolonged shelf-life than currently available nanoemulsions. | 11-26-2015 |