Folkman, US
Brandon Folkman, Venice, CA US
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20150193894 | MITIGATING UNAUTHORIZED CONTENT CLAIMS - For mitigating unauthorized content claims, an identification module ranks a plurality of content according to a value policy. The plurality of content is provided through a content host. Each content item of the plurality of content is associated with at least one authorized claimant. The identification module further identifies an unauthorized claim for a content item of the plurality of content by an unauthorized claimant. A mitigation module mitigates the unauthorized claim. | 07-09-2015 |
Cache Folkman, Bettendorf, IA US
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20090101245 | Method for Surface Cooling Steel Slabs to Prevent Surface Cracking, and Steel Slabs Made by That Method - A method is provided for the continuous casting, cutting, and continued heat treatment of steel slabs, particularly those having cracking-prone alloy formulations, without requiring the use of water spray quench cooling equipment. | 04-23-2009 |
Cache Child Folkman, Bettendorf, IA US
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20130328252 | FURNACE DIRECT EVACUATION SYSTEM - An evacuation system for an electric arc furnace that includes a combustion chamber downstream of the electric arc furnace, for receiving exhaust comprising gas and particulate from the electric arc furnace. The evacuation system also includes a dropout section downstream of the combustion chamber, for receiving the exhaust from the combustion chamber, for collecting the particulate, and for allowing the gas to pass through the dropout section to an exhaust duct. | 12-12-2013 |
Chad M. Folkman, San Jose, CA US
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20150148218 | STRONTIUM COBALTITE OXYGEN SPONGE CATALYST AND METHODS OF USE - Rapid, reversible redox activity may be accomplished at significantly reduced temperatures, as low as about 200° C., from epitaxially stabilized, oxygen vacancy ordered SrCoO | 05-28-2015 |
Chad M. Folkman, Chicago, IL US
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20130168233 | APPARATUS AND METHODS FOR HETEROEPITAXIAL GROWTH USING PULSED LASER AND SPUTTERING DEPOSITION WITH REAL-TIME, IN SITU RHEED IMAGING - Apparatus and methods for the heteroepitaxial growth of multilayered structures using an integrated magnetron sputtering and PLD with continuous, in situ, real-time RHEED imaging are provided. The apparatus for carrying out the methods are equipped with a magnetron sputtering system, a PLD system and a RHEED system associated with a single vacuum chamber. | 07-04-2013 |
Judah Folkman, Brookline, MA US
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20080248030 | Method of Treating Angiogenic Diseases - The present invention relates to methods for treating cancer comprising administering an anti-VEGF (vascular endothelial growth factor) monoclonal antibody (e.g. Avastin) and a N-(2-hydroxypropyl)methacrylamide (HPMA) copolymer-TNP-470 conjugate (e.g. Caplostatin) to a patient in need thereof. | 10-09-2008 |
20090176874 | TNP-470 POLYMER CONJUGATES AND USE THEREOF - The present invention relates to conjugates of water-soluble polymers and o-(chloracetyl-carbamoyl) fumagillol (TNP-470) and use of those conjugates as specific intracellular carriers of the TNP-470 into tumor vessels. The present invention further relates to use of those conjugates to lower the neurotoxicity of TNP-470. Preferably, the polymer has a molecular weight in the range of 100 Da to 800 kDa. More preferably, the polymer has a molecular weight no greater than 60 kDa. Most preferably, the polymer has a molecular weight in the range of 15 kDa to 40 kDa. | 07-09-2009 |
20090209497 | METHOD OF TREATING LYMPHANGIOLEIOMYOMATOSIS (LAM) - The invention provides a method for the treatment of Lymphangioleiomyomatosis (LAM) in the human subject in need thereof. The method comprises administering to the subject an effective amount of doxycycline or a salt thereof. The invention further provides a method for monitoring the efficacy of treatment. Treatment efficacy is monitored by measuring MMP levels. Reduction in MMP levels indicates that the treatment is effective. | 08-20-2009 |
20090280190 | ANTI-ANGIOGENIC PEPTIDES FROM THE N-TERMINUS OF ENDOSTATIN - Provided herein are anti-angiogenic comprising the N-terminal end of endostatin, nucleic acids encoding the same, pharmaceutical preparations comprising an effective amount of the peptide and nucleic acids and use of the pharmaceuticals in treating or preventing diseases or conditions associated with undesirable angiogenesis. | 11-12-2009 |
20130178386 | PLATELET BIOMARKERS FOR THE DETECTION OF DISEASE - The present inventors have surprisingly discovered that platelets sequester angiogenic regulators and prevent their degradation. Thus, by analyzing levels of angiogenic regulators in platelets, it is now possible to detect angiogenic activity, even at an early stage. By monitoring for changes in angiogenic activity, the presence of cancer or other angiogenic diseases or disorders can be predicted. | 07-11-2013 |
20150104406 | METAP-2 INHIBITOR POLYMERSOMES FOR THERAPEUTIC ADMINISTRATION - Described herein are MetAP-2 inhibitors and compositions and formulations thereof, and more particularly compositions and formulations of MetAP-2 inhibitors wherein the MetAP-2 inhibitor is associated with a block copolymer comprising a hydrophilic polymer moiety and a hydrophobic polymer moiety. The present invention also relates to compositions and formulations comprising MetAP-2 inhibitors for oral administration or administration via routes such as topical or ocular administration. The present invention also provides methods to treat conditions associated with or related to the over-expression or over-activity of MetAP-2 by administering the compositions and formulations comprising MetAP-2 inhibitors as disclosed herein. | 04-16-2015 |
Judah M. Folkman, Boston, MA US
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20090042229 | PLATELET BIOMARKERS FOR CANCER - The present invention relates to the fields of immunology and biochemistry. Particularly, the present invention describes methods, devices and kits for early detection of clinical conditions having associated changes in systemic angiogenic activity, particularly cancers, inflammatory conditions, infections, and events associated with pregnancy and abortion. | 02-12-2009 |
Mark Alan Folkman, Redondo Beach, CA US
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20080225288 | Imaging Systems and Methods - Imaging systems and methods are provided. In one embodiment, an image system is disclosed that comprises a Raman gain medium configured to receive an image from a target area and a tunable laser configured to pump light into the Raman gain medium over a plurality of first wavelengths to induce amplification of the image over a plurality of second wavelengths strokes shifted from the plurality of first wavelengths. The image system further comprises an image detector system that receives and processes the amplified image over the plurality of second wavelengths. | 09-18-2008 |
Mark L. Folkman, Twin Falls, ID US
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20100239718 | Use of polydimethylsiloxane and/or siloxane (silicone) derived chemical compounds in the suppression of mold and spoilage on harvested forages - The invention outlines the use of polydimethylsiloxane (PDMS) copolymer and/or a siloxane derived chemical compounds in the suppression of mold, heating and spoilage in animal feedstuffs and forage products. The PDMS compound and derivatives thereof are also found to suppress the damage resulting from oxidation within the feedstuff mass. When applied, PDMS coats the feedstuff and is included in the moisture portion of the feed or forage mass. This helps preserve the feed quality and slows the damaging effects of spoilage organisms and oxidation. | 09-23-2010 |
20110135788 | POLYSILOXANE (SILICONE) TREATMENT COMPOSITION FOR SUPPRESSION OF MOLD AND SPOILAGE ON ANIMAL FEED AND FORAGE, AND METHODS OF USING SAME - Polydimethylsiloxane and/or siloxane (silicone)-derived chemical compounds are used to coating harvested forages to protect against rain and/or other weather damage and to suppress mold and spoilage in harvested forages. The PDMS compound and derivatives thereof are also found to suppress the damage resulting from oxidation within the feedstuff mass. When applied, PDMS coats the feedstuff and is included in the moisture portion of the feed or forage mass. This helps preserve the feed quality and slows the damaging effects of spoilage organisms and oxidation. | 06-09-2011 |
20140342039 | POLYSILOXANE (SILICONE) TREATMENT COMPOSITION FOR SUPPRESSION OF MOLD AND SPOILAGE ON ANIMAL FEED AND FORAGE, AND METHOD OF USING SAME - Polydimethylsiloxane and/or siloxane (silicone)-derived chemical compounds are used to coating harvested forages to protect against rain and/or other weather damage and to suppress mold and spoilage in harvested forages. The PDMS compound and derivatives thereof are also found to suppress the damage resulting from oxidation within the feedstuff mass. When applied, PDMS coats the feedstuff and is included in the moisture portion of the feed or forage mass. This helps preserve the feed quality and slows the damaging effects of spoilage organisms and oxidation. | 11-20-2014 |
M. Judah Folkman, Brookline, MA US
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20090075369 | Angiostatin Fragments and Method of Use - Fragments of an endothelial cell proliferation inhibitor and method of use therefor are provided. The endothelial proliferation inhibitor is a protein derived from plasminogen, or more specifically is an angiostatin fragment. The angiostatin fragments generally correspond to kringle structures occurring within the endothelial cell proliferation inhibitor. The endothelial cell inhibiting activity of these fragments provides a means for inhibiting angiogenesis of tumors and for treating angiogenic-mediated disease. | 03-19-2009 |
20090137518 | Therapeutic Antiangiogenic Endostatin Compositions - Endostatin compositions capable of inhibiting endothelial cell proliferation, inhibiting angiogenesis and causing tumor regression are described. Specifically, amino acid sequences of endostatin proteins and nucleic acid sequences coding for endostatin proteins are provided. | 05-28-2009 |
Zachary Folkman, Montclair, NJ US
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20150332174 | SYSTEM AND METHOD FOR ENHANCED VEHICLE PARKING SPACE UTILIZATION - A method for facilitating utilization of a vehicle parking space. The method includes causing a computing device to graphically display a location of a personal parking space in geographic vicinity of a vehicle as being available for parking, wherein availability of said personal parking space is designated based on an input from an interest holder in the personal parking space. The method further includes receiving user selection of the available personal parking space, receiving user selection of parking time during which the vehicle will occupy the selected personal parking space, and designating the personal parking space as unavailable during the parking time selected by the user. | 11-19-2015 |