Chichilnisky
Eduardo-Jose Chichilnisky, Cardiff, CA US
Patent application number | Description | Published |
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20130204341 | METHOD AND APPARATUS FOR SELECTIVELY ACTIVATING CELLS BY APPLYING ELECTRICAL SIGNALS IN A SPATIAL PATTERN - A method and apparatus for applying electrical signals in specific spatial patterns to selectively activate sensory cells. The method comprises interfacing a population of cells with two or more electrodes, identifying target cells within the population to activate by electrical signals; and applying electrical signals in a spatial pattern to the population via the electrodes, such that the target cells are selectively activated in the desired spatial pattern. | 08-08-2013 |
20140121724 | METHOD FOR IDENTIFICATION OF RETINAL CELL TYPES INTRINSIC PROPERTIES - Retinal prostheses are configured to apply retinal stimulus signals based on retinal cell classification such as cell types or cell clusters identified based on retinal cell signals. Cell types are identified based on spontaneous or induced retinal electrical signals and analyzed based on temporal patterns of electrical activity, spatio-temporal voltage waveforms, and signal correlations that can be obtained from temporal spike patterns. Cell type indications are stored, and a signals are applied to the retina based on the stored cell type indications. | 05-01-2014 |
Eduardo-Jose Chichilnisky, Palo Alto, CA US
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20140375782 | SMART PROSTHESIS FOR FACILITATING ARTIFICIAL VISION USING SCENE ABSTRACTION - A method of providing artificial vision to a visually-impaired user implanted with a visual prosthesis. The method includes configuring, in response to selection information received from the user, a smart prosthesis to perform at least one function of a plurality of functions in order to facilitate performance of a visual task. The method further includes extracting, from an input image signal generated in response to optical input representative of a scene, item information relating to at least one item within the scene relevant to the visual task. The smart prosthesis then generates image data corresponding to an abstract representation of the scene wherein the abstract representation includes a representation of the at least one item. Pixel information based upon the image data is then provided to the visual prosthesis. | 12-25-2014 |
E.j. Chichilnisky, Del Mar, CA US
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20100236062 | Method and Apparatus for Visual Neural Stimulation - Existing epiretinal implants for the blind are designed to electrically stimulate large groups of surviving retinal neurons using a small number of electrodes with diameters of several hundred μm. To increase the spatial resolution of artificial sight, electrodes much smaller than those currently in use are desirable. In this study we stimulated and recorded ganglion cells in isolated pieces of rat, guinea pig, and monkey retina. We utilized micro-fabricated hexagonal arrays of 61 platinum disk electrodes with diameters between 6 and 25 μm, spaced 60 μm apart. Charge-balanced current pulses evoked one or two spikes at latencies as short as 0.2 ms, and typically only one or a few recorded ganglion cells were stimulated. Application of several synaptic blockers did not abolish the evoked responses, implying direct activation of ganglion cells. Threshold charge densities were typically below 0.1 mC/cm2 for a pulse duration of 100 μs, corresponding to charge thresholds of less than 100 pC. Stimulation remained effective after several hours and at high frequencies. To demonstrate that closely spaced electrodes can elicit independent ganglion cell responses, we utilized the multi-electrode array to stimulate several nearby ganglion cells simultaneously. From these data we conclude that electrical stimulation of mammalian retina with small-diameter electrode arrays is achievable and can provide high temporal and spatial precision at low charge densities. We review previous epiretinal stimulation studies and discuss our results in the context of 32 other publications, comparing threshold parameters and safety limits. | 09-23-2010 |
E. J. Chichilnisky, Del Mar, CA US
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20150209586 | INTEGRATED NANOWIRE ARRAY DEVICES FOR DETECTING AND/OR APPLYING ELECTRICAL SIGNALS TO TISSUE - An integrated nanowire device includes a first array of nanowires having a first set of characteristics and a second array of nanowires having a second set of characteristics. A processor is electrical communication with the first and second arrays of nanowires receives the first plurality of charges and generate a processor signal therefrom. The second array of nanowires may be configured to produce a stimulation current in response to the processor signal. The first or second array may be used to generate power for operation of the device, or the arrays may function as a stimulator, sensor combination to enable the device to self-regulate based on localized responses to stimulation. The device may be implanted for use as a neural stimulator. | 07-30-2015 |
Graciela Chichilnisky US
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20150283501 | System and Method for Carbon Dioxide Capture and Sequestration - A method and a system for removing carbon dioxide directly from ambient air, using a sorbent under ambient conditions, to obtain relatively pure CO | 10-08-2015 |