Patent application number | Description | Published |
20080290066 | Method of Fabricating Polymer Modulators With Etch Stop Clads - A process that comprises dry etching a trench into a side clad polymer layer using an underlying passive polymer layer as an etch stop, and then back filling the trench with an electro-optic polymer. | 11-27-2008 |
20100040322 | INTEGRATED ELECTRO-OPTIC DEVICE AND METHOD OF MAKING - An electro-optic polymer semiconductor integrated circuit includes one or more doped regions configured to drive one or more electrodes, and the electrodes are configured to drive a juxtaposed electro-optic core. The assembly may include a planarization layer disposed at least partially coplanar with the electrodes. The circuit may include an integrated multiplexer, driver configured to receive a signal from the multiplexer, at least one high speed electrode configured to be driven by the driver and modulate light energy passed through a hyperpolarizable poled chromophore regions disposed near the high speed electrode. The circuit may include a calibration storage circuit. The circuit may include, during fabrication, structures to provide voltage to a buried electrode and a shield to prevent damage from the poling field. | 02-18-2010 |
20100172619 | Single Mode Photonic Circuit Architecture and a New Optical Splitter Design Based on Parallel Waveguide Mode Conversion - The new single mode circuit (SMC) architecture is invented for photonic integrated circuits (PIC). This architecture allows using multimode waveguides or structures to construct a single mode operated PIC. The multimode sections used in such SMC based PIC possess strong lateral confinement so that the PIC can have high circuit density and high optical performance at the same time. A parallel mode converter structure is also invented here. Based on this parallel mode converter, a low loss optical splitter can be constructed for high index contrast waveguide system. | 07-08-2010 |
20110091148 | Circuit architecture for electro-optic modulation based on free carrier dispersion effect and the waveguide capacitor structures for such modulator circuitry using CMOS or Bi-CMOS process - New circuit architecture for electro-optic modulator based on free-carrier dispersion effect is invented, in which the waveguide capacitor of the modulator is embed in the circuits and physically layout together with transistors, the switching of the modulator occurs in transistors, and as the result, the electro-optical modulation occurs in the waveguide capacitor. The invented modulator is not one physical device, it is actually a circuit. Several circuit design techniques are imported, leading to several new modulator circuits that have very high operation speed and very small power consumption. Several new waveguide capacitor structures are also invented that allow high efficient modulator circuits to be built. | 04-21-2011 |
20120008897 | Single Mode Photonic Circuit Architecture and a New Optical Splitter Design Based on Parallel Waveguide Mode Conversion - The new single mode circuit (SMC) architecture is invented for photonic integrated circuits (PIC). This architecture allows using multimode waveguides or structures to construct a single mode operated PIC. The multimode sections used in such SMC based PIC possess strong lateral confinement so that the PIC can have high circuit density and high optical performance at the same time. A parallel mode converter structure is also invented here. Based on this parallel mode converter, a low loss optical splitter can be constructed for high index contrast waveguide system. | 01-12-2012 |
20120045162 | Circuit architecture for electro-optic modulation based on free carrier dispersion effect and the waveguide capacitor structures for such modulator circuitry using CMOS or Bi-CMOS process - New circuit architecture for electro-optic modulator based on free-carrier dispersion effect is invented, in which the waveguide capacitor of the modulator is embed in the circuits and physically layout together with transistors, the switching of the modulator occurs in transistors, and as the result, the electro-optical modulation occurs in the waveguide capacitor. The invented modulator is not one physical device, it is actually a circuit. Several circuit design techniques are imported, leading to several new modulator circuits that have very high operation speed and very small power consumption. Several new waveguide capacitor structures are also invented that allow high efficient modulator circuits to be built. | 02-23-2012 |
20120163749 | INTEGRATED CIRCUIT WITH OPTICAL DATA COMMUNICATION - An integrated circuit is configured for optical communication via an optical polymer stack located on top of the integrated circuit. The optical polymer stack may include one or more electro-optic polymer devices including an electro-optic polymer. The electro-optic polymer may include a host polymer and a second order nonlinear chromomophore, the host polymer and the chromophore both including aryl groups configured to interact with one another to provide enhanced thermal and/or temporal stability. | 06-28-2012 |
20150015481 | Gesture Recognition Systems - A system including a first radiation source providing a first beam and a second radiation source providing a second beam, and a radiation sensor, wherein the first beam does not overlap the second beam. In some embodiments, the radiation comprises infrared radiation. A gesture recognition system including at least one infrared sensor, a first infrared light emitting diode (LED) providing a first far-field radiation beam that extends from the first infrared LED and defines a first central ray, a second infrared light emitting diode (LED) providing a second far-field radiation beam that extends from the second infrared LED and defines a second central ray, wherein the first central ray and the second central ray define a single intersection point and an angle of intersection. | 01-15-2015 |
Patent application number | Description | Published |
20090253705 | HYDROXYMETHYL PYRROLIDINES AS BETA 3 ADRENERGIC RECEPTOR AGONISTS - The present invention provides compounds of Formula (I), pharmaceutical compositions thereof, and method of using the same in the treatment or prevention of diseases mediated by the activation of β3-adrenoceptor. | 10-08-2009 |
20090258851 | DIARYL SUBSTITUTED ALKANES - The instant invention provides compounds of Formula II which are 5-lipoxygenase activating protein inhibitors. | 10-15-2009 |
20100168076 | DIPHENYL SUBSTITUTED ALKANES - The instant invention provides compounds of Formula I which are 5-lipoxygenase activating protein inhibitors. Compounds of Formula (I) are useful as anti-atherosclerotic, anti-asthmatic, anti-allergic, anti-inflammatory and cytoprotective agents. | 07-01-2010 |
20100190761 | DIPHENYL SUBSTITUTED ALKANES - The instant invention provides compounds of Formula I which are 5-lipoxygenase activating protein inhibitors: formula (I). Compounds of Formula I are useful as anti-atherosclerotic, anti-asthmatic, anti-allergic, anti-inflammatory and cytoprotective agents. | 07-29-2010 |
20110003815 | DIPHENYL SUBSTITUTED CYCLOALKANES - The present invention provides compounds of Formula I which are FLAP inhibitors useful as anti-atherosclerotic, anti-asthmatic, anti-allergic, anti-inflammatory and cytoprotective agents. | 01-06-2011 |
20110028461 | HYDROXYMETHYL PYRROLIDINES AS BETA 3 ADRENERGIC RECEPTOR AGONISTS - The present invention provides compounds of Formula I, pharmaceutical compositions thereof, and method of using the same in the treatment or prevention of diseases mediated by the activation of β3-adrenoceptor. | 02-03-2011 |
20110028481 | HYDROXYMETHYL PYRROLIDINES AS BETA 3 ADRENERGIC RECEPTOR AGONISTS - The present invention provides compounds of Formula (I), pharmaceutical compositions thereof, and method of using the same in the treatment or prevention of diseases mediated by the activation of β3-adrenoceptor. | 02-03-2011 |
20110190346 | Diphenyl Substituted Alkanes as Flap Inhibitors - The instant invention provides compounds of formula I which are 5-lipoxygenase activating protein inhibitors. | 08-04-2011 |
20120108595 | PLATELET-ACTIVATING FACTOR RECEPTOR ANTAGONISTS - Cyclohexyl sulfonamide compounds which are platelet-activating factor (PAF) receptor antagonists. Said compounds may be useful, for example, for the treatment of atherosclerosis or other PAF-mediated disorders, including inflammatory, cardiovascular, and immune disorders. | 05-03-2012 |
20120149674 | Diaryl Substituted Alkanes - The instant invention provides compounds of Formula II which are 5-lipoxygenase activating protein inhibitors. | 06-14-2012 |
20120157432 | NOVEL PYRROLIDINE DERIVED BETA 3 ADRENERGIC RECEPTOR AGONISTS - The present invention provides compounds of Formula (I), pharmaceutical compositions thereof, and method of using the same in the treatment or prevention of diseases mediated by the activation of β3-adrenoceptor. | 06-21-2012 |
20120258963 | HYDROXYMETHYL PYRROLIDINES AS BETA 3 ADRENERGIC RECEPTOR AGONISTS - The present invention provides compounds of Formula (I), pharmaceutical compositions thereof, and method of using the same in the treatment or prevention of diseases mediated by the activation of β3-adrenoceptor. | 10-11-2012 |
20130123237 | NOVEL CYCLIC AZABENZIMIDAZOLE DERIVATIVES USEFUL AS ANTI-DIABETIC AGENTS - Novel compounds of structural formula (I) are activators of AMP-protein kinase and are useful in the treatment, prevention and suppression of diseases mediated by the AMPK-activated protein kinase. The compounds of the present invention are useful in the treatment of Type 2 diabetes, hyperglycemia, metabolic syndrome, obesity, hypercholesterolemia, and hypertension. | 05-16-2013 |
20140045746 | ANTIDIABETIC TRICYCLIC COMPOUNDS - Novel compounds of the structural formula (I), and the pharmaceutically acceptable salts thereof, are agonists of G-protein coupled receptor 40 (GPR40) and may be useful in the treatment, prevention and suppression of diseases mediated by the G-protein-coupled receptor 40. The compounds of the present invention may be useful in the treatment of Type 2 diabetes mellitus, and of conditions that are often associated with this disease, including obesity and lipid disorders, such as mixed or diabetic dyslipidemia, hyperlipidemia, hypercholesterolemia, and hypertriglyceridemia. | 02-13-2014 |
20150191495 | ANTIDIABETIC TRICYCLIC COMPOUNDS - Novel compounds of the structural formula (I), and the pharmaceutically acceptable salts thereof, are agonists of G-protein coupled receptor 40 (GPR40) and may be useful in the treatment, prevention and suppression of diseases mediated by the G-protein-coupled receptor 40. The compounds of the present invention may be useful in the treatment of Type 2 diabetes mellitus, and of conditions that are often associated with this disease, including obesity and lipid disorders, such as mixed or diabetic dyslipidemia, hyperlipidemia, hypercholesterolemia, and hypertriglyceridemia. | 07-09-2015 |
20150197516 | NOVEL BENZIMIDAZOLE TETRAHYDROPYRAN DERIVATIVES - Novel compounds described herein are activators of AMP-protein kinase and may be useful in the treatment, prevention and suppression of diseases mediated by the AMPKactivated protein kinase. The compounds of the present invention may be useful in the treatment of Type 2 diabetes, hyperglycemia, metabolic syndrome, obesity, hypercholesterolemia, and hypertension. | 07-16-2015 |
20150203487 | NOVEL AZABENZIMIDAZOLE TETRAHYDROFURAN DERIVATIVES - Novel compounds of the structural formula (I) are activators of AMP-protein kinase and may be useful in the treatment, prevention and suppression of diseases mediated by the AMPK-activated protein kinase. The compounds of the present invention may be useful in the treatment of Type 2 diabetes, hyperglycemia, metabolic syndrome, obesity, hypercholesterolemia, and hypertension. | 07-23-2015 |
20150210685 | NOVEL AZABENZIMIDAZOLE TETRAHYDROPYRAN DERIVATIVES - Novel compounds of the structural formula (I) are activators of AMP-protein kinase and may be useful in the treatment, prevention and suppression of diseases mediated by the AMPKactivated protein kinase. The compounds of the present invention may be useful in the treatment of Type 2 diabetes, hyperglycemia, metabolic syndrome, obesity, hypercholesterolemia, and hypertension. | 07-30-2015 |
20150218149 | NOVEL BENZIMIDAZOLE TETRAHYDROFURAN DERIVATIVES - Novel compounds of the structural formula (I) are activators of AMP-protein kinase and may be useful in the treatment, prevention and suppression of diseases mediated by the AMPK-activated protein kinase. The compounds of the present invention may be useful in the treatment of Type 2 diabetes, hyperglycemia, metabolic syndrome, obesity, hypercholesterolemia, and hypertension. | 08-06-2015 |
20150218183 | NOVEL BENZIMIDAZOLE HEXAHYDROFURO[3,2-B]FURAN DERIVATIVES - The novel benzimidazole hexahydrofuro[3,2-B]furan derivatives of the present invention are activators of AMP-protein kinase and may be useful in the treatment, prevention and suppression of diseases mediated by the AMPK-activated protein kinase. The compounds of the present invention may be useful in the treatment of Type 2 diabetes, hyperglycemia, metabolic syndrome, obesity, hypercholesterolemia, and hypertension. | 08-06-2015 |
20150284411 | NOVEL AZABENZIMIDAZOLE HEXAHYDROFURO[E,2-B]FURAN DERIVATIVES - Novel compounds of the structural formula (I) are activators of AMP-protein kinase and may be useful in the treatment, prevention and suppression of diseases mediated by the AMPK activated protein kinase. The compounds of the present invention may be useful in the treatment of Type 2 diabetes, hyperglycemia, metabolic syndrome, obesity, hypercholesterolemia, and hypertension. | 10-08-2015 |
Patent application number | Description | Published |
20100320763 | METHOD FOR DETERMINING A ROTOR POSITION OF AN ELECTRICAL GENERATOR IN A WIND TURBINE - A method for determining a rotor position of an electrical generator in a wind turbine is described comprising determining a voltage of the electrical generator, determining a rotor position angle estimate based on the voltage of the electrical generator, determining a subsequent rotor position angle estimate through a feedback loop, based on a combination of the voltage of the electrical generator and the rotor position angle estimate. Further, a method to real time track encoder health is described comprising determining the phase angle of a reference voltage, determining the angle difference between the rotor position and the reference voltage, and determining the differentiation of the angle difference. | 12-23-2010 |
20100327585 | Control System for an Electrical Generator and Method for Controlling an Electrical Generator - A method for validating and initializing a control system for an electrical generator connected to a power converter in a wind turbine. The method may include generating a first parameter value representing control signal for controlling the stator flux of a stator of the electrical generator, measuring a second parameter value specifying an electrical operational characteristic of the electrical generator, and determining an accuracy level of the control signal based on the first parameter value and the second parameter value, wherein the accuracy level of the control signal has to fall within a predefined threshold for the control system to be validated. | 12-30-2010 |
20110109279 | METHOD FOR DETERMINING A ROTOR POSITION OF AN ELECTRICAL GENERATOR IN A WIND TURBINE - A method for determining a rotor position of an electrical generator in a wind turbine is described comprising determining a voltage of the electrical generator, determining a rotor position angle estimate based on the voltage of the electrical generator, determining a subsequent rotor position angle estimate through a feedback loop, based on a combination of the voltage of the electrical generator and the rotor position angle estimate. Further, a method to real time track encoder health is described comprising determining the phase angle of a reference voltage, determining the angle difference between the rotor position and the reference voltage, and determining the differentiation of the angle difference. | 05-12-2011 |
20130033268 | TEST SYSTEM FOR WIND TURBINE DUMP LOAD - The present invention relates to a dump load applied in a wind turbine generator; normally it is only operating to absorb the energy during faults. Therefore in the majority time of wind turbine generator operation, the dump load is not applied, and its health condition is unknown. This invention is about a method to check the dump load condition during normal operation. | 02-07-2013 |
20130093375 | METHOD OF POSITION SENSORLESS CONTROL OF AN ELECTRICAL MACHINE - A position sensorless control methodology for electrical machines using high frequency flux vector signal injection in the estimated rotor flux rotational reference frame is provided. In one aspect, the estimated position error function is derived directly from the stator flux equation without any simplification. The method is applicable for electrical generator motoring mode operation from standstill and power generation mode operation. | 04-18-2013 |
20130187384 | METHOD OF OPERATING A WIND TURBINE, WIND TURBINE, WIND TURBINE CONTROLLING SYSTEM, AND PROCESSING SYSTEM - According to an embodiment, a method of operating a wind turbine comprising a DC-to-AC voltage converter is provided, the wind turbine being connectable to a grid via the DC-to-AC voltage converter, the method comprising: determining a line voltage of a power line connecting the DC-to-AC voltage converter to the grid; if the determined line voltage exceeds a predefined voltage threshold value, injecting reactive current into the power line, wherein the amount of reactive current injected is chosen such that an output voltage of the DC-to-AC voltage converter is kept within a predetermined voltage range. | 07-25-2013 |
20130200620 | WIND TURBINE - A wind turbine is provided. The wind turbine includes a generator, an output thereof being connectable to a power grid via a power transmission path, the power transmission path comprising a generator side converter coupled to the output of the generator, a grid side converter coupled to the power grid, and a DC link coupled between the generator side converter and the grid side converter. For diverting the generator power, a load dump arrangement is provided which includes at least one resistor, a plurality of switches, and a plurality of electrical connections which electrically connect the at least one resistor to the output of the generator and across the DC link via the plurality of switches. One common and configurable load dump is used for both converter system failures and grid failures. As compared to two separate load dumps for converter failures and grid failures, the single load dump will require a smaller space for a wind turbine. Thus, the weight and size of the power converter system may be reduced. | 08-08-2013 |
20140122011 | METHOD FOR DIAGNOSTIC MONITORING OF A WIND TURBINE GENERATOR SYSTEM - A method for diagnostic monitoring of a wind turbine generator system, said wind turbine generator system comprising a generator, a drive train, and a number of sensors for providing signals and a control system. The method comprising the selection of three sets of signals from said sensors. From the three sets of signals three conditioned sets of signals are obtained by high pass filtering said first set of signals, low pass filtering the second set of signals, and forming a moving average value on the third set of signals. Based on each of said first, second and third set of conditioned signals an evaluation is performed in order to determine a fault, where said evaluation comprises comparing the first, second and third set of conditioned signals with reference values. If said comparison indicates a fault an alarm is set. | 05-01-2014 |
20140145440 | VARIABLE WIND TURBINE HAVING A POWER DISSIPATING UNIT; A METHOD OF OPERATING A POWER DISSIPATING UNIT IN A WIND TURBINE - A variable speed wind turbine is provided. The variable speed wind turbine comprises a generator, a power converter for converting at least a portion of electrical power generated by the generator, the power converter comprising a generator-side converter, a grid-side converter and a DC (direct current) link therebetween, a power dissipating unit operatively coupled to the DC-link, and a controller. The controller is adapted to receive a request to reduce power output from the wind turbine, determine a feed forward power signal based on a reference generator power and a desired turbine power, and operate the power dissipating unit based on the feed forward power signal. | 05-29-2014 |
20150037948 | METHODS FOR FABRICATING INTEGRATED CIRCUITS WITH A HIGH-VOLTAGE MOSFET - Methods for fabricating integrated circuits are disclosed. In an exemplary embodiment, a method for fabricating an integrated circuit includes forming a silicon material layer over a semiconductor substrate. The method further includes forming a capping layer over the silicon material layer and over the memory gate stack, removing the capping layer from over the memory array region and the high-voltage MOSFET region, forming a second silicon material layer over the capping layer and over the first silicon material layer, and removing the second silicon material layer. The method further includes removing the capping layer from over the first silicon material layer in the logic device region and removing the first and second silicon material layers from the high-voltage MOSFET region. Still further, the method includes forming a photoresist material layer over the memory array region and the logic device region and exposing the semiconductor substrate to an ion implantation process. | 02-05-2015 |
20150065333 | BIFUNCTIONAL CATALYSTS FOR OXYGEN REDUCTION AND EVOLUTION REACTIONS AND RECHARGEABLE METAL AIR BATTERIES USING THE SAME - The present disclosure relates to a catalyst for a metal air battery or fuel cell comprising a mixed metal oxide consisting of at least one lanthanide element and at least two different transition metal elements. The catalyst may further comprise a conducting additive. The present disclosure further provides an air electrode, metal air battery or fuel cell comprising the disclosed catalyst, and methods for forming the disclosed catalyst. | 03-05-2015 |
20150236032 | METHODS FOR FABRICATING INTEGRATED CIRCUITS WITH A HIGH-VOLTAGE MOSFET - Methods for fabricating integrated circuits are disclosed. In an exemplary embodiment, a method for fabricating an integrated circuit includes forming a silicon material layer over a semiconductor substrate. The method further includes forming a capping layer over the silicon material layer and over the memory gate stack, removing the capping layer from over the memory array region and the high-voltage MOSFET region, forming a second silicon material layer over the capping layer and over the first silicon material layer, and removing the second silicon material layer. The method further includes removing the capping layer from over the first silicon material layer in the logic device region and removing the first and second silicon material layers from the high-voltage MOSFET region. Still further, the method includes forming a photoresist material layer over the memory array region and the logic device region and exposing the semiconductor substrate to an ion implantation process. | 08-20-2015 |
Patent application number | Description | Published |
20100054428 | Method, system, and apparatus for overriding a ring back signal - Overriding a ring back signal involves receiving a ring back signal at a communications apparatus from a communication network in response to a user-initiated connection request. The ring back signal is rendered to a user of the communications apparatus, and a user input is received at the communications device to override the ring back signal. An alternate output is rendered to the user in place of the ring back signal. | 03-04-2010 |
20120250847 | METHOD, SYSTEM, AND APPARATUS FOR OVERRIDING A RING BACK SIGNAL - Overriding a ring back signal involves receiving a ring back signal at a communications apparatus from a communication network in response to a user-initiated connection request. The ring back signal is rendered to a user of the communications apparatus, and a user input is received at the communications device to override the ring back signal. An alternate output is rendered to the user in place of the ring back signal. | 10-04-2012 |
20130056442 | OPTICAL WAVEGUIDE FABRICATION METHOD - The present invention relates to a method of manufacturing optical waveguide devices. The order of patterning/etch in the method is first a deeper etching then shallow etching. In some embodiments, the first etching forms a mesa and the second etching removes a portion of material that comprises the mesa. In addition, there can be a planarization step. The deeper trenches are desirably conducive to filling. The method may use a cross-lithography method to reduce alignment errors between multiple patterning/etching steps. The method may use an oxidation and stripping off process to smooth a surface of the waveguide and/or reduce an initial dimension of the waveguide. | 03-07-2013 |
20130266257 | OPTICAL WAVEGUIDE SWITCH - Techniques are described to form an optical waveguide switch that could reach a very high extinction ratio. In particular, this disclosure describes an asymmetric MZI, in which different waveguide capacitor structures are used in two arms of the MZI: a first arm with a waveguide capacitor to achieve the mainly phase modulation and a second arm with a waveguide capacitor to achieve mainly the magnitude modulation, respectively. Using the asymmetric MZI in accordance with this disclosure, one can design an algorithm to achieve almost unlimited extinction ration during the switching operation. | 10-10-2013 |
20130285184 | WAVEGUIDE PHOTODETECTOR AND FORMING METHOD THEREOF - Techniques are described for forming a waveguide photodetector. In one example, a method of forming a waveguide photodetector includes forming a waveguide on a substrate, e.g., silicon on insulator, depositing a first oxide coating over the waveguide and on the SOI substrate, creating a seed window through the first oxide coating to a bulk silicon layer of the SOI substrate, depositing a photodetector material into the seed window and on top of the first oxide coating over the waveguide, depositing a second oxide coating over the photodetector material and over the first oxide coating deposited over the waveguide and on the SOI substrate, and applying thermal energy to liquefy the photodetector material. | 10-31-2013 |
20130294724 | DISPERSION-CORRECTED ARRAYED WAVEGUIDE GRATING - Techniques are described for forming an arrayed waveguide grating. In one example, an arrayed waveguide grating comprises a waveguide array coupled to the output of a parallel mode converter and a concave reflective diffraction grating coupled to the output of the waveguide array, wherein the waveguide array comprises a first waveguide and a second waveguide, wherein the first waveguide of the waveguide array has a different length from the second waveguide of the waveguide array. The waveguide array has a first dispersion having a first sign and a first magnitude, wherein the concave reflective diffraction grating has a second dispersion having a second sign and a second magnitude, wherein the second sign is opposite the first sign. | 11-07-2013 |
20150189076 | METHOD, SYSTEM, AND APPARATUS FOR OVERRIDING A RING BACK SIGNAL - Overriding a ring back signal involves receiving a ring back signal at a communications apparatus from a communication network in response to a user-initiated connection request. The ring back signal is rendered to a user of the communications apparatus, and a user input is received at the communications device to override the ring back signal. An alternate output is rendered in place of the ring back signal. | 07-02-2015 |
Patent application number | Description | Published |
20090163592 | Chiral diacylhydrazine ligands for modulating the expression of exogenous genes via an ecdysone receptor complex - The present invention provides diacylhydrazine ligands and chiral diacylhydrazine ligands for use with ecdysone receptor-based inducible gene expression systems. Thus, the present invention is useful for applications such as gene therapy, large scale production of proteins and antibodies, cell-based screening assays, functional genomics, proteomics, metabolomics, and regulation of traits in transgenic organisms, where control of gene expression levels is desirable. An advantage of the present invention is that it provides a means to regulate gene expression and to tailor expression levels to suit the user's requirements. | 06-25-2009 |
20120116090 | Chiral Diacylhydrazine Ligands for Modulating the Expression of Exogenous Genes via an Ecdysone Receptor Complex - The present invention provides diacylhydrazine ligands and chiral diacylhydrazine ligands for use with ecdysone receptor-based inducible gene expression systems. Thus, the present invention is useful for applications such as gene therapy, large scale production of proteins and antibodies, cell-based screening assays, functional genomics, proteomics, metabolomics, and regulation of traits in transgenic organisms, where control of gene expression levels is desirable. An advantage of the present invention is that it provides a means to regulate gene expression and to tailor expression levels to suit the user's requirements. | 05-10-2012 |
20120316066 | Chiral Diacylhydrazine Ligands for Modulating the Expression of Exogenous Genes via an Ecdysone Receptor Complex - The present invention provides diacylhydrazine ligands and chiral diacylhydrazine ligands for use with ecdysone receptor-based inducible gene expression systems. Thus, the present invention is useful for applications such as gene therapy, large scale production of proteins and antibodies, cell-based screening assays, functional genomics, proteomics, metabolomics, and regulation of traits in transgenic organisms, where control of gene expression levels is desirable. An advantage of the present invention is that it provides a means to regulate gene expression and to tailor expression levels to suit the user's requirements. | 12-13-2012 |
20150099636 | Chiral Diacylhydrazine Ligands for Modulating the Expression of Exogenous Genes via an Ecdysone Receptor Complex - The present invention provides diacylhydrazine ligands and chiral diacylhydrazine ligands for use with ecdysone receptor-based inducible gene expression systems. Thus, the present invention is useful for applications such as gene therapy, large scale production of proteins and antibodies, cell-based screening assays, functional genomics, proteomics, metabolomics, and regulation of traits in transgenic organisms, where control of gene expression levels is desirable. An advantage of the present invention is that it provides a means to regulate gene expression and to tailor expression levels to suit the user's requirements. | 04-09-2015 |
Patent application number | Description | Published |
20080316030 | MOBILE COMMUNICATION DEVICE, ANTI-THEFT METHOD AND SYSTEM - A mobile communication device is provided herein. The mobile communication device includes a touch unit for generating a trigger signal when detecting a touch, a controller for generating an audible alarm in response to the trigger signal, and a transceiver for communicating wirelessly with an anti-theft device. The audible alarm, transmitted to the anti-theft device via the transceiver, is for enabling the anti-theft device to output a first alarm. An anti-theft system and method are also provided. | 12-25-2008 |
20130194807 | METHOD FOR GENERATING DIFFUSE REFLECTION LIGHT AND DEVICE THEREOF - A method for generating diffuse reflection light and a diffuse reflection lamp are provided. The diffuse reflection lamp comprises a reflective plate ( | 08-01-2013 |
20130207332 | ADJUSTMENT MECHANISM - An adjustment mechanism includes a first adjustment assembly and a second adjustment assembly. The first adjustment assembly includes a first regulating member and a second regulating member. The first regulating member includes a bearing plate and a first supporting portion protruding from the bearing plate. The first supporting portion includes an arcuate first supporting surface. The second regulating member includes a base body and a second supporting portion protruding from the base body away from the first supporting portion. The second supporting portion includes an arcuate second supporting surface. The second adjustment assembly includes a mounting member latched with the base body. First supporting surface resists the base body, to enable the bearing plate to rock along a curvature relative to the base body. Second supporting surface resists the mounting member, to enable the bearing plate and the base body to rock relative to the mounting member. | 08-15-2013 |
20130270071 | CONVEYING DEVICE - A conveying device includes a supporting platform, a rolling member, a driving member, and a conveying assembly. The rolling member rotatably is mounted on the supporting platform. The driving member is connected to the rolling member, for driving the rolling member to rotate along an axis. The conveying assembly includes a supporting member, a fixing member, and several rollers. The fixing member is mounted on a side of the supporting member towards the supporting platform, and defines an arcuate mounting surface. The rollers are mounted on the arcuate mounting surface, and resist the rolling member. Sets of two rollers are located on opposite sides of the rolling member. The rotation axes of the rollers are inclined relative to the rotation axis of the rolling member, which enable the rotation of the rolling member to drive the rollers to rotate and slide along the rolling member. | 10-17-2013 |
20130305088 | ELECTRONIC DEVICE AND TEST CARD THEREOF - A testing card includes a power interface, a plurality of serial ports connected to a plurality of test instruments. The microprocessor includes a processing unit having been burnt with a plurality of test programs, the processing unit is configured to execute one of the test programs according a user selection and generate a test command, and a serial ports management unit configured to convert the test command into a control signal, and send the control signal to a corresponding test instrument via the corresponding one of the serial port to control the test instrument to test a target device. An electronic device using the test card is also provided. | 11-14-2013 |
20140010627 | ABSORBING MECHANISM - An absorbing mechanism includes a positioning member, an absorbing member, and at least one separating member. The positioning member defines a receiving chamber, for receiving a plurality of workpieces. The attaching member is constructed for absorbing the workpieces. The at least one separating member comprises a main body and a detaching portion. The main body is mounted on the positioning member. The detaching portion protrudes from the main body toward an axis of the positioning member, and forming an inclined surface away from the main body. The inclined surface defines at least one blow hole. The inclined surface towards the receiving chamber. | 01-09-2014 |
20140042262 | EXPANSION DEVICE FOR HOLDING AND SECURING ROLLED MATERIAL - An expansion device configured for securely holding a rolled material when the rolled material is handled on roller is disclosed. The expansion device includes a roller spindle, two expansion members, a fixing sleeve, a clamping nut, and a locking member. The locking member moves toward the expansion members, so that the two expansion members expand toward the fixing sleeve, and protrusions which are formed on the expansion members are pressed outward through fixing holes of the fixing sleeve, and then resist against an inner surface of rolled material inside a rolling hole formed therethrough the rolled material. Thus, the rolled material is held securely by the expansion device. | 02-13-2014 |
20140042761 | CLAMPING DEVICE - A clamping device includes a driving mechanism and a pair of clamping mechanisms. Each clamping mechanism includes a clipping member, an installing plate, a positioning member, a resisting plate, and an elastic member. The clipping members are movably connected to the driving mechanism. A protrusion protrudes from the clipping member, and includes a first inclined surface. The installing plate defines an opening. The protrusion passes through the opening. The positioning member is inserted into the installing plate and fixed with the clipping member. The resisting plate is movably mounted on the installing plate. An abutting portion protrudes from the resisting plate, and passes through the opening. The abutting portion comprises a second inclined surface resisting the first inclined surface, the elastic member is sandwiched between the installing plate and the resisting plate, for providing a resetting force to the resisting plate. | 02-13-2014 |
20140048995 | CLAMPING MECHANISM - A clamping mechanism includes a mounting plate, a driving assembly, and a clamping assembly. The mounting plate defines four through grooves. The driving assembly includes a driver mounted on the mounting plate, and a connecting member connected to the driver. The clamping assembly includes a reversing member mounted on the mounting plate, four clamping members, four transferring members, and four elastic members. The clamping members are movably mounted in the through grooves. The transferring members are wound on the reversing member. An end of each transferring member is connected to the connecting member, an opposite end of each transferring member is connected to the corresponding clamping member. The elastic members are sleeved on the transferring members, and resisting against the clamping members. The clamping members move toward the reversing member driven by the driver, for clamping a workpiece. | 02-20-2014 |
20140060220 | POSITIONING DEVICE AND POSITIONING MECHANISM FOR SAME - A positioning device includes a base and two positioning mechanisms oppositely positioned on the base to position a workpiece. Each positioning mechanism includes a driver positioned on the base, a mounting member mounted on the base, a gear rack, a gear, and a positioning member. The mounting member defines a sliding groove. The gear rack slidably is received in the sliding groove and connected with the driver. The gear is rotatably connected with the mounting member and is meshed with the gear rack. The positioning member is fixedly-connected with the gear. The driver drives the gear rack to slide along the sliding groove to make the positioning member rotate and outstretch into an interior of the workpiece. The drivers drive two positioning members apply two opposite forces on the workpiece to positioning the workpiece. | 03-06-2014 |
20140061004 | FEEDING DEVICE USED IN SURFACE TREATING PROCESS - A feeding device is used for hanging a workpiece on a fixture. The fixture includes two elastic portions. The feeding device includes a base for carrying the workpiece, a mounting seat, a driving member for driving the mounting seat, a guiding assembly, and a driving mechanism mounted on the mounting seat and connected to the guiding assembly for driving the guiding assembly. The guiding assembly passes through the base, and includes first and second guiding members. The driving member is capable of driving the first and second guiding members in the workpiece. The driving mechanism is capable of driving the first and second guiding members move away from each other to a position adjacent the inner walls of the workpiece, and the elastic portions resist against the inner walls of the workpiece, such that the workpiece is hung on the fixture. | 03-06-2014 |
20140080609 | TORQUE LIMITER - A torque limiter includes an input shaft connected to a driving source, an output shaft connected to a driven load, a shaft sleeve, and an adjustment mechanism. The input shaft includes a positioning post. The output shaft includes a resisting post. The shaft sleeve includes a cam surface and a resisting surface, and defines a cam groove in a periphery. When the driven load is in a predetermined torque range, the positioning post is engaged in the cam groove, the output shaft is rotated by the input shaft and drives the driven load. When the driven load reaches overload torque amount, the cam surface moves relative to the resisting post, the cam surface is separated from the resisting post, such that the input shaft is separated from the output shaft. Thus, the output shaft and the driven load are protected from damaged by torque overload. | 03-20-2014 |
20140083621 | VACUUM-POWERED FILM-APPLYING MECHANISM - A vacuum-powered film-applying mechanism for applying a flexible film to a workpiece includes a bracket, a suction member, and a rotating joint. The suction member is rotatably mounted on the bracket, and defines a peripheral surface and a plurality of suction chambers therein, and by virtue of a vacuum created in the interior of the suction member, a length of flexible film is attracted and adhered. The rotating joint on the bracket communicates with the plurality of the suction chamber, through the rotating joint, air is supplied and exhausted from the plurality of suction chambers progressively, on a one by one basis, to pick up and roll the flexible film onto itself, and by supplying air to the plurality of suction chambers one by one, unrolls and releases the flexible film onto the workpiece with a low incidence of trapping air bubbles. | 03-27-2014 |
20140203546 | CONNECTING STRUCTURE FOR VACUUM SYSTEM - A connecting structure includes housing, a first fixing member, a second fixing member, a sealing member, and an elastic member. A stepped hole is defined on the housing, and includes a first vent, a second vent, and a third vent communicating with each other. A diameter of the second vent is gradually decreased from the first vent toward the third vent, thereby forming a resisting surface on a periphery of the second vent. The first fixing member and the second fixing member are mounted on opposite ends of the housing. The sealing member includes a sealing portion with an exhaust opening. The sealing member is received in the first and second vents, and resisting against the first fixing member. The exhaust opening communicates with the first and second vents. The elastic member is received in the third vent, and resisting between the second fixing member and the sealing member. | 07-24-2014 |
20150129139 | UNLOADING MECHANISM - A unloading mechanism for removing workpieces from a transporting film can include a loading assembly and a unloading assembly coupled to the loading assembly. The loading assembly can include a base, a first driving member and an absorbent member. The base can include a base body, a first guiding member slidably extending through the base body, and a plurality of pushing members coupled to the base body. The first driving member can be coupled to the base body. The absorbent member can be coupled to the first guiding member. The absorbent member can define a plurality of receiving holes, and the pushing members can be received in the receiving holes. The unloading assembly can include a second driving member coupled to the first driving member, and a stopping member coupled to the second driving member adjacent to the absorbent member. | 05-14-2015 |
20150151530 | PEELING DEVICE - A label peeling device includes a mounting bracket, a power member attached to the mounting bracket, a driving member driven by the power member; and a pressing assembly coupled to a first end of the driving member. A clamping mechanism includes a sliding member coupled to a second end of the driving member, and a clamping assembly configured to clamp a backing paper. A first resisting member is attached to the mounting bracket, and presses against the clamping assembly. The pressing assembly and the clamping mechanism are configured to be urged toward each other by a driving force imparted by the power member, the first resisting member drive the clamping assembly to the sliding member, and thereby cause at least one of the plurality of wafers to be removed from the backing paper. | 06-04-2015 |
20150196984 | TURNOVER APPARATUS - A turnover apparatus is configured for flipping a workpiece. The turnover apparatus includes an rotatable frame, a cam assembly, two racks located at the two opposite sides of the cam assembly, a first clamping module and a second clamping module located at the two opposite sides of the workpiece. The rotatable frame includes a power input shaft. The cam assembly is coiled around the power input shaft, and includes an eccentric cam. Each clamping module includes a plurality of transmission assemblies and clamping assemblies. The rotatable frame can rotate around the cam assembly. At the same time, the clamping assemblies can clamp or loosen the workpiece by the driving force of the racks and the transmission assemblies. | 07-16-2015 |
Patent application number | Description | Published |
20110236501 | INJECTABLE DUAL DELIVERY ALLOGRAPH BONE/POLYMER COMPOSITE FOR TREATMENT OF OPEN FRACTURES - A biodegradable polyurethane scaffold, comprising at least one polyisocyante, polyisocyanate prepolymer, or both, at least one polyester polyol, at least one catalyst, wherein the density of said scaffold is from about 50 to about 250 kg m-3 and the porosity of the scaffold is greater than about 70 (vol %) and at least 50% of the pores are interconnected with another pore, and wherein the scaffold incorporates at least one biologically active component in powder form. | 09-29-2011 |
20120183622 | ENCAPSULATED CELLS AND COMPOSITES THEREOF - Embodiments of the present invention comprise biodegradable composites including a polyurethane component and cells encapsulated in gel beads, as well as methods of making such composite and uses thereof. In certain embodiments the gel beads are alginate beads. The composites may be moldable and/or injectable. After implantation or injection, a composition may be set to form a porous composite that provides mechanical strength, supports the in-growth of cells, and/or delivers cells to particular tissues. Inventive composites have the advantage of being able to fill irregularly shaped implantation sites, deliver cells in a localized and noninvasive manner, and optimize cell proliferation and differentiation of delivered cells. | 07-19-2012 |
20130171026 | POROUS MEMBRANES HAVING A POLYMERIC COATING AND METHODS FOR THEIR PREPARATION AND USE - A modified porous membrane comprising a polymer coating grafted to a porous membrane is described. The polymer coatings grafted to the porous membranes generally comprise a polymer of variable length of an electron beam (e-beam) reactive moiety, designated “poly-(A) | 07-04-2013 |
20130171368 | POROUS MEMBRANES HAVING A POLYMERIC COATING AND METHODS FOR THEIR PREPARATION AND USE - A modified porous membrane comprising a polymer coating grafted to a porous membrane is described. The polymer coatings grafted to the porous membranes generally comprise a polymer of variable length of an electron beam (e-beam) reactive moiety, designated “poly-(A) | 07-04-2013 |
20130171618 | POROUS MEMBRANES HAVING A POLYMERIC COATING AND METHODS FOR THEIR PREPARATION AND USE - A modified porous membrane comprising a polymer coating grafted to a porous membrane is described. The polymer coatings grafted to the porous membranes generally comprise a polymer of variable length of an electron beam (e-beam) reactive moiety, designated “poly-(A) | 07-04-2013 |
20130171619 | POROUS MEMBRANES HAVING A HYDROPHILIC COATING AND METHODS FOR THEIR PREPARATION AND USE - A modified porous membrane comprising a polymeric hydrophilic coating grafted to a porous membrane is described. The polymeric hydrophilic coatings grafted to the porous membranes comprise, for example, a PEG moiety such as a PEGMA, a PEGDA, or a TMPET, wherein the polymeric hydrophilic coating on the porous membrane decreases non-specific binding of unwanted material to the porous membrane and increases the signal to noise ratio in immunoassays, in vitro diagnostic tests, and point of care tests. Methods of making these modified porous membranes are also disclosed. | 07-04-2013 |
20130171669 | POROUS MEMBRANES HAVING A HYDROPHILIC COATING AND METHODS FOR THEIR PREPARATION AND USE - A modified porous membrane comprising a polymeric hydrophilic coating bonded to a porous membrane is described. The polymeric hydrophilic coatings grafted to the porous membranes comprise, for example, a PEG moiety such as a PEGMA, a PEGDA, or a TMPET, wherein the polymeric hydrophilic coating on the porous membrane decreases non-specific binding of unwanted material to the porous membrane and increases the signal to noise ratio in immunoassays, in vitro diagnostic tests, and point of care tests. Methods of making these modified porous membranes are also disclosed. | 07-04-2013 |
20130289265 | METHODS AND COMPOSITIONS FOR EXTRACTION AND STORAGE OF NUCLEIC ACIDS - The present disclosure generally relates to solid matrices for the extraction, stabilization, and storage of nucleic acids, particularly RNA, in a dry format under ambient conditions for a prolonged period of time. Methods for extracting, collecting, and recovering nucleic acids from the solid compositions are also described. | 10-31-2013 |
20130338351 | METHODS AND COMPOSITIONS FOR EXTRACTION AND STORAGE OF NUCLEIC ACIDS - A solid matrix for the extraction, stabilization, and storage of nucleic acids is provided. At least one protein denaturant, and at least one acid or acid-titrated buffer reagent are impregnated in a dry state therein the matrix; and the matrix is configured to provide an acidic pH on hydration. The matrix is configured to extract nucleic acids from a sample and stabilize the extracted nucleic acids, particularly RNA, in a dry format under ambient conditions for a prolonged period of time. Methods for collecting and recovering the nucleic acids stored in the dry solid matrix are also described. | 12-19-2013 |
Patent application number | Description | Published |
20120056590 | Very Long Cycling of Lithium Ion Batteries with Lithium Rich Cathode Materials - Lithium ion batteries can be activated and then cycled to exploit a moderate fraction of the discharge cycling capacity such that the discharge capacity and average discharge voltage stay within initial values for thousands of cycles. The superior cycling performance has been achieved at relatively high discharge rates and for practical battery formats. Lithium ion battery performance can also be achieved with superior cycling performance with partially activated batteries such that good discharge capacities can be exploited for many thousands of cycles before the discharge capacity and average discharge voltage drops more than 20% from initial values. The positive electrode active material can be a lithium rich metal oxide. The activation of the battery can comprise phase changes of the active materials. As described herein, the phase changes can be manipulated to exploit a reasonable fraction of the available high capacity of the material while providing outstanding cycling stability. | 03-08-2012 |
20120105007 | LITHIUM ION BATTERIES WITH SUPPLEMENTAL LITHIUM - Supplemental lithium can be used to stabilize lithium ion batteries with lithium rich metal oxides as the positive electrode active material. Dramatic improvements in the specific capacity at long cycling have been obtained. The supplemental lithium can be provided with the negative electrode, or alternatively as a sacrificial material that is subsequently driven into the negative electrode active material. The supplemental lithium can be provided to the negative electrode active material prior to assembly of the battery using electrochemical deposition. The positive electrode active materials can comprise a layered-layered structure comprising manganese as well as nickel and/or cobalt. | 05-03-2012 |
20120107680 | Lithium Ion Batteries with Supplemental Lithium - Supplemental lithium can be used to stabilize lithium ion batteries with lithium rich metal oxides as the positive electrode active material. Dramatic improvements in the specific capacity at long cycling have been obtained. The supplemental lithium can be provided with the negative electrode, or alternatively as a sacrificial material that is subsequently driven into the negative electrode active material. The supplemental lithium can be provided to the negative electrode active material prior to assembly of the battery using electrochemical deposition. The positive electrode active materials can comprise a layered-layered structure comprising manganese as well as nickel and/or cobalt. | 05-03-2012 |
20130043843 | HIGH CAPACITY LITHIUM ION BATTERY FORMATION PROTOCOL AND CORRESPONDING BATTERIES - Battery formation protocols are used to perform initial charging of batteries with lithium rich high capacity positive electrode to result a more stable battery structure. The formation protocol generally comprises three steps, an initial charge step, a rest period under an open circuit and a subsequent charge step to a selected partial activation voltage. The subsequent or second charge voltage is selected to provide for a desired degree of partial activation of the positive electrode active material to achieve a desired specific capacity while providing for excellent stability with cycling. The formation protocol is particularly effective to stabilize cycling for compositions with moderate lithium enrichment. | 02-21-2013 |
20130157147 | Low Temperature Electrolyte for High Capacity Lithium Based Batteries - Electrolytes for lithium based batteries are described with good temperature tolerance over appropriate temperature ranges for uses in vehicles. In particular, the electrolytes are suitable for high voltage operation over 4.4V and can provide high rate performance. The electrolytes generally comprise a solvent that is a mixture of ethylene carbonate, dimethyl carbonate and ethylmethyl carbonate. Alternatively, a solvent combination of fluoroethylene carbonate and dimethyl carbonate was used. A primary lithium salt is includes at a concentration greater than about 1.05M. The electrolyte generally also comprises a lithium salt additive. The electrolytes can provide some battery capacity down to at least −40° C. while providing good performance also at elevated temperatures of 45° or more, and the corresponding batteries can be cycled to several thousand cycles. | 06-20-2013 |
20140050972 | LITHIUM ION BATTERIES WITH HIGH ENERGY DENSITY, EXCELLENT CYCLING CAPABILITY AND LOW INTERNAL IMPEDANCE - Batteries with particularly high energy capacity and low internal impedance have been described herein. The batteries can exhibit extraordinary long cycling with acceptable low amounts of fade. Pouch batteries using high specific capacity lithium rich metal oxide as positive electrode material combined with graphitic carbon anode can reach an energy density of at least about 180 Wh/kg at a rate of C/3 from 4.35V to 2V at room temperature while having a room temperature areas specific DC resistance of no more than about 75 ohms-cm | 02-20-2014 |
20140302392 | UNIFORM STABILIZATION NANOCOATINGS FOR LITHIUM RICH COMPLEX METAL OXIDES AND ATOMIC LAYER DEPOSITION FOR FORMING THE COATING - Stabilization coating that are uniform and penetrating have been found to provide desirable stabilization coatings for lithium rich metal oxide cathode active materials. In particular, the uniform and penetrating coatings can be particularly desirable for improving storage stability of batteries formed with the active material. The stabilization coatings can be inert metal oxides, such as aluminum oxide. The uniform and penetrating stabilization coatings can be formed using atomic layer deposition. The coatings can further effectively stabilize cycling of the batteries, and batteries formed with the stabilization coating can exhibit modest increases in DC electrical resistance. | 10-09-2014 |
20150037690 | ELECTROLYTES FOR STABLE CYCLING OF HIGH CAPACITY LITHIUM BASED BATTERIES - Electrolytes are described with additives that provide good shelf life with improved cycling stability properties. The electrolytes can provide appropriate high voltage stability for high capacity positive electrode active materials. The core electrolyte generally can comprise from about 1.1M to about 2.5M lithium electrolyte salt and a solvent that consists essentially of fluoroethylene carbonate and/or ethylene carbonate, dimethyl carbonate and optionally no more than about 40 volume percent methyl ethyl carbonate, and wherein the lithium electrolyte salt is selected from the group consisting of LiPF | 02-05-2015 |
20150050535 | LITHIUM ION BATTERIES WITH HIGH CAPACITY ANODE ACTIVE MATERIAL AND GOOD CYCLING FOR CONSUMER ELECTRONICS - Battery designs are provided that exhibit commercially suitable cycling properties for consumer electronics with silicon based active materials in the electrodes. The batteries can have stacked or wound electrodes and suitable electrode designs. | 02-19-2015 |
20150364748 | HIGH CAPACITY LITHIUM ION BATTERY FORMATION PROTOCOL AND CORRESPONDING BATTERIES - Battery formation protocols are used to perform initial charging of batteries with lithium rich high capacity positive electrode to result a more stable battery structure. The formation protocol generally comprises three steps, an initial charge step, a rest period under an open circuit and a subsequent charge step to a selected partial activation voltage. The subsequent or second charge voltage is selected to provide for a desired degree of partial activation of the positive electrode active material to achieve a desired specific capacity while providing for excellent stability with cycling. The formation protocol is particularly effective to stabilize cycling for compositions with moderate lithium enrichment. | 12-17-2015 |
20150364796 | LOW TEMPERATURE ELECTROLYTE FOR HIGH CAPACITY LITHIUM BASED BATTERIES - Electrolytes for lithium based batteries are described with good temperature tolerance over appropriate temperature ranges for uses in vehicles. In particular, the electrolytes are suitable for high voltage operation over 4.4V and can provide high rate performance. The electrolytes generally comprise a solvent that is a mixture of ethylene carbonate, dimethyl carbonate and ethylmethyl carbonate. Alternatively, a solvent combination of fluoroethylene carbonate and dimethyl carbonate was used. A primary lithium salt is includes at a concentration greater than about 1.05M. The electrolyte generally also comprises a lithium salt additive. The electrolytes can provide some battery capacity down to at least −40° C. while providing good performance also at elevated temperatures of 45° or more, and the corresponding batteries can be cycled to several thousand cycles. | 12-17-2015 |
Patent application number | Description | Published |
20120122914 | Sustained-release composition containing tetrahydropyrido[4,3-b]indole derivatives and preparation of the derivatives - The present invention relates to a sustained-release composition containing 2,3,4,5-tetrahydro-2,8-dimethyl-5-[2-(6-methyl-3-pyridyl)ethyl]-1H-pyrido[4,3-b]indole or a pharmaceutically acceptable salt thereof as an active ingredient, preparation thereof and the compound. The composition is suitable for oral administration by one time per day, and achieves the peak plasma concentration at 1.0 to 3 hours after oral administration. The composition is suitable for manufacturing a medicament for treatment of cognitive dysfunction syndrome, Alzheimer's disease, Parkinson's disease, Huntington's disease, or senile dementia. | 05-17-2012 |
20120149334 | METHOD OF AND SYSTEM FOR EXTENDING THE WISPr AUTHENTICATION PROCEDURE - A method and system for completing the authentication process of a user device in a second communication network (such as Wi-Fi or WiMAX) utilizes the user credential (such as a SIM card, a USIM card, or a RUIM card) of a first communication network (such as GSM, CDMA, EDGE, or LTE). A client, such as a software module, executes on the wireless device. An authentication platform retrieves the SIM card credential information in the first communication network and passes the information to the authentication platform of the second communication network, thereby granting the client access to the second communication after the authentication platform validates with the first communication network. | 06-14-2012 |
20120264402 | METHOD OF AND SYSTEM FOR UTILIZING A FIRST NETWORK AUTHENTICATION RESULT FOR A SECOND NETWORK - A method and system for completing the authentication process in a second communication network (such as Wi-Fi or WiMAX) utilizes a user credential of a first communication network, such as GSM, UMTS, CDMA, or LTE. Preferably, the user credential is a SIM card, a USIM card, a R-UIM card, or a functionally similar component. The system includes a client and an authentication platform that retrieves Service State information of the user credential in the first communication network and passes the information to the authentication platform of the second communication network. The client is wanted access to the second communication network after the authentication platform validates the client's service and subscription status with the first communication network. | 10-18-2012 |
20140214956 | METHOD AND APPARATUS FOR MANAGING SESSIONS OF DIFFERENT WEBSITES - A method, apparatus, and/or computer program product manages sessions of different websites. Respective session identifiers of a plurality of websites are recorded, where each of the respective session identifiers of the plurality of websites identifies a session established in response to a page open operation for a respective website, and where pages of the plurality of websites are integrated into one page on one website. An operation request for a page of a first website of the plurality of websites is received. In response to receiving the operation request, a session synchronization request message that requests that a session of the first website be synchronized with sessions of the plurality of websites is generated and transmitted from the first website to other websites from the plurality of websites. | 07-31-2014 |
Patent application number | Description | Published |
20130236083 | DETECTION OF THIN LINES FOR SELECTIVE SENSITIVITY DURING RETICLE INSPECTION USING PROCESSED IMAGES - A detection method for a spot image based thin line detection is disclosed. The method includes a step for generating a band limited spot image from a transmitted and reflected optical image of the mask. The spot image is calibrated to minimize a plurality of optical aberrations from the spot image. The spot image is restored back to a mask image to allow at least one of: a more reliable segmentation between thin line and non-thin line areas on the mask image or a more accurate line width measurement for facilitating segmentation. Thin line features and non-thin lines features are distinguished on the restored mask image. Areas containing thin line features are grown while preventing the thin line growth from encroaching the non-thin line features. | 09-12-2013 |
20130236084 | RETICLE DEFECT INSPECTION WITH SYSTEMATIC DEFECT FILTER - A stream of defect data is received from a reticle inspection system. The defect data identifies defects that were detected for a plurality of different portions of a reticle. Before reviewing the defect data to determine whether the reticle passes inspection and as the stream of defect data continues to be received, some of the defects are automatically grouped with other most recently one or more received defects on as form groups of substantially matching defects. Before reviewing the defect data to determine whether the reticle passes inspection and after all of the defect data for the reticle is received, one or more of the groups of defects that have a number above a predetermined threshold are automatically filtered from the defect data on as to form filtered defect data. The filtered defect data may then be provided to a review station for determining whether the reticle passes. | 09-12-2013 |
20140205179 | RETICLE DEFECT INSPECTION WITH SYSTEMATIC DEFECT FILTER - Disclosed are methods and apparatus for inspecting a photolithographic reticle. A stream of defect data is received from a reticle inspection system, wherein the defect data identifies a plurality of defects that were detected for a plurality of different portions of the reticle. Before reviewing the defect data to determine whether the reticle passes inspection and as the stream of defect data continues to be received, some of the defects are automatically grouped with other most recently one or more received defects so as form groups of substantially matching defects. Before reviewing the defect data to determine whether the reticle passes inspection and after all of the defect data for the reticle is received, one or more of the groups of defects that have a number above a predetermined threshold are automatically filtered from the defect data so as to form filtered defect data. The filtered defect data may then be provided to a review station for determining whether the reticle passes. | 07-24-2014 |
20140341462 | MACHINE LEARNING METHOD AND APPARATUS FOR INSPECTING RETICLES - Apparatus and methods for inspecting a photolithographic reticle are disclosed. A reticle inspection tool is used at one or more operating modes to obtain images of a plurality of training regions of a reticle, and the training regions are identified as defect-free. Three or more basis training images are derived from the images of the training regions. A classifier is formed based on the three or more basis training images. The inspection system is used at the one or more operating modes to obtain images of a plurality of test regions of a reticle. Three or more basis test images are derived from to the test regions. The classifier is applied to the three or more basis test images to find defects in the test regions. | 11-20-2014 |
20140369593 | DETECTION OF THIN LINES FOR SELECTIVE SENSITIVITY DURING RETICLE INSPECTION USING PROCESSED IMAGES - A detection method for a spot image based thin line detection is disclosed. The method includes a step for constructing a band limited spot image from a transmitted and reflected optical image of the mask. The spot image is calibrated to reduce noise introduced by the one or more inspection systems. Based on the band limited spot image, a non-printable feature map is generated for the non-printable features and a printable feature map is generated for the printable features. One or more test images of the mask are analyzed to detect defects on such mask. A sensitivity level of defect detection is reduced in areas of the one or more test images defined by the non-printable feature map, as compared with areas of the one or more test images that are not defined by the non-printable features map | 12-18-2014 |
20150279014 | MESOSCOPIC DEFECT DETECTION FOR RETICLE INSPECTION - In some embodiments, a method and/or system may include detecting defects in photomasks. The method may include acquiring a first image of a first die. The method may include acquiring a second image of a second die. In some embodiments, the method may include dividing the first and the second image into a number of first and second portions respectively. The method may include reducing one or more differences in sizing of the first and the second portions. In some embodiments, the method may include determining a difference in a function derived from an image intensity between the corresponding first and second portions. The method may include summing the differences in the function between the corresponding first and second portions. The method may include detecting mesoscopic scale defects in the second die. | 10-01-2015 |
Patent application number | Description | Published |
20140234942 | SUBSTRATES AND METHODS FOR COLLECTION, STABILIZATION AND ELUTION OF BIOMOLECULES - A solid substrate for the extraction, stabilization, and storage of proteins is provided. The substrate includes: a polysaccharide, such as melezitose under a substantially dry state. The substrate is configured to extract proteins from a sample and stabilize the extracted proteins in a dry format under ambient conditions for a prolonged period of time. Methods for collecting and recovering the proteins stored in the dry solid substrate are also described. | 08-21-2014 |
20150118683 | SUBSTRATES AND ASSOCIATED METHODS FOR ELUTION OF NUCLEIC ACIDS - A solid substrate for biological sample storage under dry-state and elution of biomolecules is provided. The dry, solid substrate comprises a surface modified with a plurality of hydrophilic groups; and the substrate is comprised of one or more protein denaturing agents impregnated therein under a substantially dry state. A method for elution of biomolecules from biological samples is also provided. The compositions disclosed herein provide for enhanced elution and recovery of biomolecules, such as nucleic acids, from the sample. The sample is disposed on a substrate, dried to a substantially dry state; eluted from the biological sample dried on the substrate by rehydrating the substrate in an elution buffer. | 04-30-2015 |
20150119566 | SUBSTRATES AND ASSOCIATED METHODS FOR ELUTION OF NUCLEIC ACIDS - A solid substrate for biological sample storage under dry-state and elution of biomolecules is provided. The dry, solid substrate is coated with saccharides, such as monosaccharides, oligosaccharides, polysaccharides or combinations thereof, and the substrate is comprised of one or more protein denaturing agents impregnated therein under a substantially dry state. A method for elution of biomolecules from biological samples is also provided. The compositions disclosed herein provide for enhanced elution and recovery of biomolecules, such as nucleic acids, from the sample. The sample is disposed on a substrate, dried to a substantially dry state; eluted from the biological sample dried on the substrate by rehydrating the substrate in an elution buffer. | 04-30-2015 |
20150176056 | ELECTROSPUN FIBERS FOR PROTEIN STABLIZIATION AND STORAGE - An electrospinning approach is disclosed for generating a dissolvable formulation of a reagent of interest in a nanoscale fiber medium. In one embodiment, the nanoscale fibers can incorporate and stabilize biological agents of interest, such as for storage at room temperature for extended periods. In one implementation, the fibers can be produced in a continuous manner and dissolve rapidly. | 06-25-2015 |
20160002622 | METHODS FOR CAPTURING NUCLEIC ACIDS - A method is provided herein, wherein the method of capturing a target nucleic acid, comprises applying a nucleic acid capture probe to a capture zone of a needs definition, wherein the nucleic acid capture probe having a first molecular weight comprises at least a sequence that is complimentary to at least a portion of the target nucleic acid sequence and the nucleic acid capture probe is substantially immobilized at the capture zone of the substrate. The method further comprises applying a sample comprising the target nucleic acid having a second molecular weight to a sample application zone of the substrate; wherein the sample comprising the target nucleic acid flows across a length of the substrate from the sample application zone to the capture zone by lateral flow, and the target nucleic acid is captured by the nucleic acid capture probes by hybridization to the capture zone. | 01-07-2016 |