Patent application number | Description | Published |
20130302273 | COMPOSITIONS DERIVED FROM STEM CELL RELEASED MOLECULES & METHODS FOR FORMULATION THEREOF - Compositions for use in treatment of a variety of tissue diseases include stem cells and stem cell released molecules (SRM's) suspended in an aqueous solution with a cellulosic material or other thickening agent. The stem cells and SRM's can be derived from one or more distinct cell lines. The SRM's can further include one or more mucins, cytokines, or growth factors. Exemplary formulations include stem cells and SRMs derived from epithelial stem cells, corneal limbal stem cells, and fibroblasts. Other compositions and methods for formulation thereof are described. | 11-14-2013 |
20140205563 | COMPOSITIONS DERIVED FROM STEM CELL RELEASED MOLECULES & METHODS FOR FORMULATION THEREOF - Compositions for use in treatment of a variety of tissue diseases include stem cells and stem cell released molecules (SRM's) suspended in an aqueous solution with a cellulosic material or other thickening agent. The stem cells and SRM's can be derived from one or more distinct cell lines. The SRM's can further include one or more mucins, cytokines, or growth factors. Exemplary formulations include stem cells and SRMs derived from epithelial stem cells, corneal limbal stem cells, and fibroblasts. Other compositions and methods for formulation thereof are described. | 07-24-2014 |
20150071877 | BIOACTIVE COMPOSITIONS AND METHODS FOR THEIR PREPARATION AND USE - A method for preparing a bioactive composition containing conditioned cell culture medium is disclosed. The method comprises culturing cells of two or more eukaryotic cell line to form conditioned culture media, separating the cultured cells from the conditioned culture media, and combining conditioned culture media to form a bioactive composition. Novel bioactive compositions, formulations and their use in treating of a variety of diseases and health conditions are also disclosed. | 03-12-2015 |
Patent application number | Description | Published |
20080228265 | TISSUE ANCHORS, SYSTEMS AND METHODS, AND DEVICES - Systems, devices and methods for securing tissue including the annulus of a mitral valve. The systems, devices and methods may employ catheter based techniques and devices to plicate tissue and perform an annuloplasty. | 09-18-2008 |
20080228267 | DEVICES AND METHODS FOR INTRODUCING ELEMENTS INTO TISSUE - Systems, devices and methods for securing tissue including the annulus of a mitral valve. The systems, devices and methods may employ catheter based techniques and devices to plicate tissue and perform an annuloplasty. | 09-18-2008 |
20140094906 | TISSUE ANCHORS, SYSTEMS AND METHODS, AND DEVICES - Systems, devices and methods for securing tissue including the annulus of a mitral valve. The systems, devices and methods may employ catheter based techniques and devices to plicate tissue and perform an annuloplasty. | 04-03-2014 |
20150134055 | Tissue fastening systems and methods utilizing magnetic guidance - Catheter based systems and methods for securing tissue including the annulus of a mitral valve. The systems and methods employ catheter based techniques and devices to plicate tissue and perform an annuloplasty. | 05-14-2015 |
Patent application number | Description | Published |
20150119877 | ELECTRODE ABLATION BALLOON CATHETER - Methods, systems, and devices for providing treatment to a tissue in body lumens are described. The system may include a support shaft, an expansion member coupled with a distal portion of the support shaft, and an ablation structure wrapped around the expansion member less than a circumference of the expansion member configured to engage the body lumens with varying sizes. The ablation structure may include multiple separately wired or separately controlled longitudinal electrodes, longitudinal electrode zones, or both, such that each longitudinal electrode or longitudinal electrode zone may be selectively enabled or selectively disabled. The expansion member may include a single highly-compliant balloon, a single non-compliant balloon, multiple non-compliant balloons, or a multi-chambered non-compliant balloon. | 04-30-2015 |
20150119879 | UNFURLING ELECTRODE DEVICES WITH THE MULTIPLE LONGITUDINAL ELECTRODE SEGMENTS - Methods, systems, and devices for providing treatment to a tissue in body lumens are described. The system may include a catheter, an expansion member coupled with a distal portion of the catheter, an ablation structure including one or more longitudinal electrode segments, and an ablation structure support coupled to the ablation structure configured to at least partially unfurl as the expansion member expands and furl as the expansion member contracts. The ablation structure may include multiple separately wired and/or separately controlled longitudinal electrodes, longitudinal electrode zones, or both, such that each longitudinal electrode or longitudinal electrode zone may be selectively enabled or selectively disabled. In some instances, one or more springs are coupled to the ablation structure configured to promote unfurl or furl around the expansion member. In some instances, one or more protection elements are be positioned along the catheter. | 04-30-2015 |
20150119880 | UNFURLING ELECTRODE DEVICES WITH SPRING - Methods, systems, and devices for providing treatment to a tissue in body lumens are described. The system may include a catheter, an expansion member coupled with a distal portion of the catheter, an ablation structure including one or more longitudinal electrode segments, and an ablation structure support coupled to the ablation structure configured to at least partially unfurl as the expansion member expands and furl as the expansion member contracts. The ablation structure may include multiple separately wired and/or separately controlled longitudinal electrodes, longitudinal electrode zones, or both, such that each longitudinal electrode or longitudinal electrode zone may be selectively enabled or selectively disabled. In some instances, one or more springs are coupled to the ablation structure configured to promote unfurl or furl around the expansion member. In some instances, one or more protection elements are be positioned along the catheter. | 04-30-2015 |
20150119881 | UNFURLING ELECTRODE DEVICES WITH THE PROTECTION ELEMENT - Methods, systems, and devices for providing treatment to a tissue in body lumens are described. The system may include a catheter, an expansion member coupled with a distal portion of the catheter, an ablation structure including one or more longitudinal electrode segments, and an ablation structure support coupled to the ablation structure configured to at least partially unfurl as the expansion member expands and furl as the expansion member contracts. The ablation structure may include multiple separately wired and/or separately controlled longitudinal electrodes, longitudinal electrode zones, or both, such that each longitudinal electrode or longitudinal electrode zone may be selectively enabled or selectively disabled. In some instances, one or more springs are coupled to the ablation structure configured to promote unfurl or furl around the expansion member. In some instances, one or more protection elements are be positioned along the catheter. | 04-30-2015 |
20160045189 | DESIGNS AND METHODS TO FACILITATE SWALLOWING OF A TETHERED CELL COLLECTION DEVICE - Methods, apparatuses and systems are described for administering a swallowable cell collection device to a patient. Methods include releasing a swallowable bundle of string of the cell collection device from a bundling apparatus, maintaining the string in a swallowable bundle while releasing the swallowable bundle from the bundling apparatus, and placing the swallowable bundle on the tongue of the patient. Methods also include constraining a retrieval string of the cell collection device in a swallowable bundle with a dissolvable band and placing the swallowable bundle on the tongue of the patient. | 02-18-2016 |
20160081670 | SCORED RETAINING FEATURES IN A COMPRESSIBLE CELL COLLECTION DEVICE - Methods, apparatuses and systems for collecting cells from a body lumen are described. The system may include a swallowable cell collection device comprising an abrasive and substantially non-absorbent material configured to collect cells from the body lumen by scraping a surface of the body lumen and a swallowable and dissolvable capsule comprising a plurality of scoring features and configured to releasably retain the cell collection device. Additionally, a method of manufacturing an apparatus for collecting cells from a body lumen is described. The method may include encapsulating a swallowable cell collection device comprising an abrasive and substantially non-absorbent material within a swallowable and dissolvable capsule and mechanically weakening the capsule with a plurality of scoring features. | 03-24-2016 |
20160081671 | USE OF EXPANSION-FORCE ELEMENTS IN A COMPRESSIBLE CELL COLLECTION DEVICE - Methods, apparatuses and systems for collecting cells from a body lumen are described. The system may include a swallowable cell collection device comprising an abrasive and substantially non-absorbent material in a compressed configuration and configured to collect cells from the body lumen by scraping a surface of the body lumen. The system may further include one or more expansion elements coupled with the cell collection device configured to expand the cell collection device from the compressed configuration. | 03-24-2016 |
20160081672 | TAPERED GEOMETRY IN A COMPRESSIBLE CELL COLLECTION DEVICE - Methods, apparatuses and systems for collecting cells from a body lumen are described. A system may include a cell collection device comprising an abrasive material configured to collect cells from the body lumen by scraping a surface of the body lumen. The cell collection device may have a first end with a first diametric dimension and a second end with a second diametric dimension, wherein the second diametric dimension is larger than the first diametric dimension. | 03-24-2016 |
20160081677 | REGIONS OF VARYING PHYSICAL PROPERTIES IN A COMPRESSIBLE CELL COLLECTION DEVICE - Methods, apparatuses and systems for collecting cells from a body lumen are described. The system may include a cell collection device and a capsule configured to releasably retain the cell collection device. The cell collection device may comprise a plurality of distinct regions, each region comprising one or more material properties. In some instances, at least one material property of at least one distinct region differs from at least one material property of at least one other distinct region. The distinct regions may comprise different materials or may comprise the same material where at least one of the distinct regions is mechanically or chemically altered to yield the at least one differing material property. | 03-24-2016 |
Patent application number | Description | Published |
20090206500 | Pre-heated combustion air in treating ceramic components - Systems and processes are disclosed to provide pre-heated air to a furnace configured to treat ceramic green bodies which are made of a particulate material and a combustible fugitive binder. In one embodiment the furnace includes a heater disposed within an intake conduit which supplies pre-heated air to a combustion chamber disposed within the furnace. | 08-20-2009 |
20100028645 | Adaptive supports for green state articles and methods of processing thereof - Supports for green ceramic stereolithography parts are disclosed which limit or minimize deformation during burnout and sintering. The supports have a time/temperature thermal response tuned to the part being sintered and control geometrically-induced distortion or gravimetric sag. | 02-04-2010 |
20120015797 | METHOD AND APPARATUS ASSOCIATED WITH ANISOTROPIC SHRINK IN SINTERED CERAMIC ITEMS - A manufacturing method for producing ceramic item from a photocurable ceramic filled material by stereolithography. The method compensates for the anisotropic shrinkage of the item during firing to produce a dimensionally accurate item. | 01-19-2012 |
20130154161 | METHOD AND APPARATUS ASSOCIATED WITH ANISOTROPIC SHRINK IN SINTERED CERAMIC ITEMS - A manufacturing method for producing ceramic item from a photocurable ceramic filled material by stereolithography. The method compensates for the anisotropic shrinkage of the item during firing to produce a dimensionally accurate item. | 06-20-2013 |
20140284848 | METHOD AND APPARATUS ASSOCIATED WITH ANISOTROPIC SHRINK IN SINTERED CERAMIC ITEMS - A manufacturing method for producing ceramic item from a photocurable ceramic filled material by stereolithography. The method compensates for the anisotropic shrinkage of the item during firing to produce a dimensionally accurate item. | 09-25-2014 |
Patent application number | Description | Published |
20090256284 | Method for producing ceramic stereolithography parts - In addition to working curves, other equally important, but previously not understood, relationships exist for both the green strength and the cured line width of ceramic-loaded resins. These characteristics of cured parts are strongly affected by the dose rate, a parameter usually controlled with laser power. Multiple smaller doses are used to produce a total integrated dose. Multiple exposures benefit from using high power to produce a fast process. However, since the dose for a given layer is broken into several smaller doses, the negative effect of high power on strength and cured linewidth is reduced. | 10-15-2009 |
20110037848 | METHOD AND APPARATUS FOR CALIBRATING A PROJECTED IMAGE MANUFACTURING DEVICE - A method for calibrating a manufacturing device that manufactures solid parts by projecting images onto a photo-curable substrate includes providing the manufacturing device including a projector and an optical train, positioning an imaging plate at a manufacturing position relative to the manufacturing device, and providing a contrasting image on the imaging plate. The method further includes projecting a test image from the projector through the optical train onto the contrasting image and calibrating the projector and/or the optical train in response to the test image projected onto the contrasting image. The method further includes manufacturing a solid component with the manufacturing device after the calibrating. | 02-17-2011 |
20110048172 | SYSTEMS AND METHODS FOR LEACHING A MATERIAL FROM AN OBJECT - Embodiments of the present invention include methods and systems for leaching material from an object. Examples include leaching ceramic from metallic components. Other embodiments include apparatuses, systems, devices, hardware, methods, and combinations for leaching systems. Further embodiments, forms, features, aspects, benefits, and advantages of the present application shall become apparent from the description and figures provided herewith. | 03-03-2011 |
20110048665 | CORROSION RESISTANCE FOR A LEACHING PROCESS - A corrosion resistance system is disclosed that can be used in conjunction with a leaching device for removal of a mold from a cast component. The corrosion resistance system includes a container having a working fluid, such as a caustic fluid. A cast component and mold is placed within the container and a power supply is coupled to the component. During operation of the corrosion resistance system the cast component can be configured as an anode or as a cathode to provide for anodic or cathodic corrosion resistance. In one form the power supply is connected with an electrical conductor to the container and the cast component placed in electrical coupling with the container. An inert gas purge can supply an inert gas to the container. A vacuum pump can be used to remove gas from the container. Furthermore, an oxygen getter can be used in some embodiments. | 03-03-2011 |
20110068517 | SUPPORT FOR A FIRED ARTICLE - An article produced using, among other techniques, free-form fabrication having a binder matrix and particles can be supported during a temperature processing, such as burn-out of the binder matrix, with a support composition to maintain geometry and/or alleviate changes in geometry of the article. The support composition can take a variety of forms such as foams, two phase materials, plastic powders, carbon powders, etc. The support material is sacrificed during the thermal processing, such as through decomposition. Such a decomposition can occur when the support composition evolves into a carbonaceous structure. The support composition can also oxidize to a gas, melt, or vaporize, among other types of sacrificial action. | 03-24-2011 |
20110240245 | SYSTEMS AND METHODS FOR FILTERING MOLTEN METAL - One embodiment of the present invention is a unique filter and a method for manufacturing the same. Another embodiment is a unique system for casting a metallic object. Another embodiment is a unique method of filtering a molten metal. Other embodiments include apparatuses, systems, devices, hardware, methods, and combinations for filtering molten metal. Further embodiments, forms, features, aspects, benefits, and advantages of the present application shall become apparent from the description and figures provided herewith. | 10-06-2011 |
Patent application number | Description | Published |
20110212593 | CMP Process Flow for MEMS - The present invention generally relates to the formation of a micro-electromechanical system (MEMS) cantilever switch in a complementary metal oxide semiconductor (CMOS) back end of the line (BEOL) process. The cantilever switch is formed in electrical communication with a lower electrode in the structure. The lower electrode may be either blanket deposited and patterned or simply deposited in vias or trenches of the underlying structure. The excess material used for the lower electrode is then planarized by chemical mechanical polishing or planarization (CMP). The cantilever switch is then formed over the planarized lower electrode. | 09-01-2011 |
20120181638 | METHOD FOR MEMS DEVICE FABRICATION AND DEVICE FORMED - The present invention generally relates to methods for producing MEMS or NEMS devices and the devices themselves. A thin layer of a material having a lower recombination coefficient as compared to the cantilever structure may be deposited over the cantilever structure, the RF electrode and the pull-off electrode. The thin layer permits the etching gas introduced to the cavity to decrease the overall etchant recombination rate within the cavity and thus, increase the etching rate of the sacrificial material within the cavity. The etchant itself may be introduced through an opening in the encapsulating layer that is linearly aligned with the anchor portion of the cantilever structure so that the topmost layer of sacrificial material is etched first. Thereafter, sealing material may seal the cavity and extend into the cavity all the way to the anchor portion to provide additional strength to the anchor portion. | 07-19-2012 |
20130032453 | ELIMINATION OF SILICON RESIDUES FROM MEMS CAVITY FLOOR - The present invention generally relates to a MEMS device in which silicon residues from the adhesion promoter material are reduced or even eliminated from the cavity floor. The adhesion promoter is typically used to adhere sacrificial material to material above the substrate. The adhesion promoter is the removed along with then sacrificial material. However, the adhesion promoter leaves silicon based residues within the cavity upon removal. The inventors have discovered that the adhesion promoter can be removed from the cavity area prior to depositing the sacrificial material. The adhesion promoter which remains over the remainder of the substrate is sufficient to adhere the sacrificial material to the substrate without fear of the sacrificial material delaminating. Because no adhesion promoter is used in the cavity area of the device, no silicon residues will be present within the cavity after the switching element of the MEMS device is freed. | 02-07-2013 |
20130299926 | METHOD FOR MEMS DEVICE FABRICATION AND DEVICE FORMED - The present invention generally relates to methods for producing MEMS or NEMS devices and the devices themselves. A thin layer of a material having a lower recombination coefficient as compared to the cantilever structure may be deposited over the cantilever structure, the RF electrode and the pull-off electrode. The thin layer permits the etching gas introduced to the cavity to decrease the overall etchant recombination rate within the cavity and thus, increase the etching rate of the sacrificial material within the cavity. The etchant itself may be introduced through an opening in the encapsulating layer that is linearly aligned with the anchor portion of the cantilever structure so that the topmost layer of sacrificial material is etched first. Thereafter, sealing material may seal the cavity and extend into the cavity all the way to the anchor portion to provide additional strength to the anchor portion. | 11-14-2013 |