Patent application number | Description | Published |
20130176556 | Multiwell plate lid for improved optical measurements - A lid for multiwell plates, allowing improved optical measurement of liquid samples within its wells, while mitigating evaporation from said samples, is disclosed. A surface element protrudes from the bottom of the lid into the fluid within a well. The protruding element may be hollow or solid such that light directed into the element may act to capture or direct the beam while preventing backscatter from reaching one or more detectors. The protruding element may direct the beam from the well without requiring the beam to pass through a fluid/air interface. The angle and shape of the lid surfaces and/or light absorbing/blocking colorization may be employed to minimize or eliminate back reflection. Evaporation is controlled by physically capping the well with the lid, either sealing against the face at the top of the well or the inside surface of the well. | 07-11-2013 |
20130215424 | METHOD OF CHARACTERIZING INTERACTIONS AND SCREENING FOR EFFECTORS - This invention enables high throughput detection of small molecule effectors of particle association, as well as quantification of association constants, stoichiometry, and conformation. Given a set of particle solutions having different concentrations, dynamic light scattering measurements are used to determine the average hydrodynamic radius, as a function of concentration. The series of average hydrodynamic radii as a function of concentration are fitted with stoichiometric association models containing the parameters of molar mass, modeled concentrations, and modeled hydrodynamic radii of the associated complexes. In addition to the average hydrodynamic radii value analysis, the experimental data may be fit/analyzed in alternate ways. This method may be applied to a single species that is self-associating or to multiple species that are hetero-associating. This method may also be used to characterize and quantify the association between a modulator and the associating species. | 08-22-2013 |
20150077739 | Multiwell plate lid for improved optical measurements - A lid for a multiwell plates which allows improved light scattering measurement of liquid samples within the wells of a multiwell plate, and which at the same time mitigates evaporation from said samples is disclosed. A surface element protrudes from the bottom of the lid into the fluid in a well. The protruding element may be hollow or solid, and the beam of light, directed into the element may act to capture or direct the beam while preventing backscatter from reaching the light scattering detector or detectors. The protruding element may thus direct the beam from the well without the beam having to pass through a fluid/air interface. The angle and shape of the lid surfaces may be optimized to minimize or eliminate back-reflection. Light absorbing and/or light blocking colorization may also be employed to minimize or eliminate back reflection. Evaporation is controlled by physically capping the well with the lid, either sealing against the face at the top of the well or the inside surface of the well. | 03-19-2015 |
Patent application number | Description | Published |
20140046243 | APPARATUS AND METHODS FOR CLOT DISRUPTION AND EVACUATION - The apparatus includes a catheter having a combined infusion/aspiration lumen, a three lumen proximal portion and a two lumen distal portion. An infusion/aspiration valve located at the distal end of the catheter facilitates performing infusion and aspiration through the same lumen, which in turn reduces the number of lumens, and enables the combined infusion/aspiration lumen to be made larger without the need to increase the diameter of the catheter. Differing material properties in the proximal and distal portions of the catheter enable the proximal portion to be made stiffer for pushability, while the distal portion is more flexible to navigate tortuous vasculature and enable a greater amplitude agitator to be received within the catheter. | 02-13-2014 |
20140046244 | APPARATUS AND METHODS FOR CLOT DISRUPTION AND EVACUATION - The apparatus includes a catheter having a combined infusion/aspiration lumen, a three lumen proximal portion and a two lumen distal portion. An infusion/aspiration valve located at the distal end of the catheter facilitates performing infusion and aspiration through the same lumen, which in turn reduces the number of lumens, and enables the combined infusion/aspiration lumen to be made larger without the need to increase the diameter of the catheter. Differing material properties in the proximal and distal portions of the catheter enable the proximal portion to be made stiffer for pushability, while the distal portion is more flexible to navigate tortuous vasculature and enable a greater amplitude agitator to be received within the catheter. | 02-13-2014 |
20140379012 | Introducer Sheaths, Thrombus Collection Devices, and Associated Methods - A sheath comprises an elastomeric tube having a self-expanding scaffold coupled to a wall. The scaffold can expand to a diameter larger than the tube diameter to provide an enlarged distal opening. An aspiration catheter has a balloon and an aspiration port so that occlusive material can be removed from a blood vessel by drawing the balloon through the vessel while simultaneously aspirating through the port. | 12-25-2014 |
Patent application number | Description | Published |
20100056994 | PUMPING APPARATUS WITH SECURE LOADING FEATURES - A pumping apparatus and pump set for use to deliver a supply of liquid to a patient. The feeding set has a conduit for the nutrient liquid and a safety interlock device associated with the conduit. The pumping apparatus has a pumping device and a control system for controlling operation of the pump. An electromagnetic radiation source is operatively connected to the control system of the pump for emitting an electromagnetic radiation signal in a direction for striking the safety interlock device of the feeding set. The safety interlock device being adapted to affect the direction of the electromagnetic radiation. An electromagnetic radiation detector is operatively connected to the control system for receiving the electromagnetic radiation signal when the direction is affected by the safety interlock device, and provides an indication to the control system that the feeding set conduit is properly positioned in the feeding pump. | 03-04-2010 |
20110021979 | Enteral Feeding Set and Interlock Device Therefor - An enteral feeding set for an enteral feeding pump having a control system for controlling operation of the pump to supply nutrient liquid to a patient through the enteral feeding set loaded in the pump, a source of electromagnetic radiation for emitting electromagnetic radiation and an electromagnetic radiation detector for receiving the electromagnetic radiation. The enteral feeding set includes a conduit for carrying nutrient liquid to a patient and a safety interlock device associated with the conduit adapted for mounting in the pump. The safety interlock device includes an electromagnetic radiation propagation affecting member formed to affect the propagation of electromagnetic radiation from the source of electromagnetic radiation through the safety interlock device and block visible light when properly loaded on the pump for directing the electromagnetic radiation from the source of electromagnetic radiation to the detector. | 01-27-2011 |
20110077565 | REDUCED NOISE PNEUMATIC COMPRESSION GARMENT - A reduced noise pneumatic compression garment comprises a flexible member having a bladder that can conform to a limb of the human body. A port in fluid communication with the bladder has an air flow path through which pressurized air is delivered to the bladder to inflate the bladder. A porous insert is located within the flow path of the port between the air inlet and the air outlet is provided for reducing noise from air flow through the port into the inflatable chamber. A method of quietly inflating a pneumatic compression garment is also disclosed. | 03-31-2011 |
20120121444 | MOUNT FOR A COMPRESSION CONTROL UNIT - A compression control unit for a compression device includes a mount on the back of a housing for mounting the compression control unit on a bed unit. The mount includes a securing portion spaced from a back of the housing and lying in a plane generally opposing the back of the housing. The securing portion partially defines a channel for receiving a part of the bed unit to secure the compression control unit to the bed unit. Spaced apart wing portions extend generally upward and laterally outward relative to the securing portion. The wing portions are configured so that fluid tubing secured to an outlet of the compression control unit can be wrapped around the wing portions when the compression control unit is mounted on the bed unit. | 05-17-2012 |
20130282047 | Safety Connector Assembly - A connector assembly includes first and second mating connectors that can be joined to make a fluid connection. The connectors are constructed to discriminate improper connectors so that no fluid tight connection can be formed with improper connectors. The connector assembly can be used with a system for compression therapy to prevent deep vein thrombosis. The first connector includes a bleed passage. | 10-24-2013 |
Patent application number | Description | Published |
20100224031 | GRAPHITE / TITANIUM HAMMER - According to disclosure, the hammer has a head made of striking grade steel. The handle comprises a 6-4 titanium hand grip and over strike plate insert in the handle and under the head. The head has an eye for accommodating a handle which in a preferred embodiment is made of a graphite titanium composite comprising from about 60 to 65% graphite by weight and from about 35 to 45% 6-4 titanium. The head of hammer has a claw end and a striking head. Also disclosed is a method of manufacturing the device of the disclosure comprising using one or more bladder compressed carbon fiber processes to anneal the graphite, titanium and steel components of the hammer. | 09-09-2010 |
20120085983 | STRIKING TOOL - A hammer that that reduces vibration and provides advantageous balance and mass distribution having a handle portion comprising an I-shape sectional profile and a head comprising a cavity formed therethrough. The hammer may further comprise various nail or other fastener removal structures, such as a claw, slots, notches, or the like. The hammer may further include a nail-starter with magnetic nail retention. | 04-12-2012 |
20120091409 | STRIKING TOOLS - Hammers suitable to different tasks are described. Each hammer includes features to reduce vibration and provides advantageous balance and mass distribution. The hammers have a handle portion comprising an I-shape sectional profile and a head comprising a cavity formed therethrough. Each hammer may further comprise various nail or other fastener removal structures, such as a claw, slots, notches, or the like. The hammer may further include a nail-starter with magnetic nail retention. | 04-19-2012 |
20120096650 | PULLING TOOL - A multi-function tool having a handle portion and a plurality of structures operable therewith for the performance of a plurality of functions. The multi-function tool allows fast and convenient transition between any of the plurality of functions in order to enable completion of jobs or tasks requiring such functions without acquisition, storage, and/or maintenance of a plurality of specialized tools. | 04-26-2012 |
20120110745 | PULLING TOOLS - A multi-function tool having a handle portion and a plurality of structures operable therewith for the performance of a plurality of functions. The multi-function tool allows fast and convenient transition between any of the plurality of functions in order to enable completion of jobs or tasks requiring such functions without acquisition, storage, and/or maintenance of a plurality of specialized tools. | 05-10-2012 |
20120112144 | GRAPHITE / TITANIUM HAMMER - According to disclosure, the hammer has a head made of striking grade steel. The handle comprises a 6-4 titanium hand grip and over strike plate insert in the handle and under the head. The head has an eye for accommodating a handle which in a preferred embodiment is made of a graphite titanium composite comprising from about 60 to 65% graphite by weight and from about 35 to 45% 6-4 titanium. The head of hammer has a claw end and a striking head. Also disclosed is a method of manufacturing the device of the disclosure comprising using one or more bladder compressed carbon fiber processes to anneal the graphite, titanium and steel components of the hammer. | 05-10-2012 |
20120119173 | GRAPHITE / TITANIUM HAMMER WITH WOODEN HANDLE - According to disclosure, the hammer has a head made of striking grade steel. The handle comprises a 6-4 titanium hand grip and over strike plate insert in the handle and under the head. The head has an eye for accommodating a handle which in a preferred embodiment is made of a graphite titanium composite comprising from about 60 to 65% graphite by weight and from about 35 to 45% 6-4 titanium. The head of hammer has a claw end and a striking head. Also disclosed is a method of manufacturing the device of the disclosure comprising using one or more bladder compressed carbon fiber processes to anneal the graphite, titanium and steel components of the hammer. | 05-17-2012 |
20120272530 | MULTI-EDGE CHISEL - A multi-edge chisel which can be operated in a hands-free manner is made from a unitary main body with at least one opening. The main body has a flat profile, with a blade on one end, and at least one striking plate on the opposite end. | 11-01-2012 |
20130186891 | MARKETING DEVICE - A marketing device that can protect merchandise from damage, debris, and theft, conveys size information of the merchandise, reusable, and provides an aesthetically pleasing way for display in retail stores comprising a cap, enclosure, and extension in one embodiment, or can be used separately. The cap may further comprise bands, other catching devices, or the like. The enclosure may further include a cavity capable of storing a plurality of trailer hitch balls. | 07-25-2013 |