Curcio
Alberto Curcio, Torre Annunziata IT
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20150359887 | Heat-Sensitive Nanoparticle System - A heat-sensitive system comprising at least one nanoparticle bound covalently to at least one thermolabile molecule comprising an azo —N═N— functional group —N═N— in turn bound covalently to at least one active molecule selected from a fluorophore molecule and a drug is disclosed. The system converts an electromagnetic radiation into thermal energy exposed to an alternating magnetic field. Uses of the system are also disclosed. | 12-17-2015 |
Annalisa Curcio, Torre Annunziata (na) IT
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20110212904 | GALACTOSYLATED PRO-DRUGS OF NON-STEROIDAL ANTI-INFLAMMATORIES WITH IMPROVED PHARMACOKINETIC CHARACTERISTICS AND REDUCED TOXICITY OF THE STARTING DRUG - Pro-drugs of all non-steroidal anti-inflammatories with free acid function derivatized with an ester group, which have the general structural formula given below (I) where A is: aspirin, diflunisal, benorylate, ibufenac, diclofenac, indomethacin, sulindac, ketorolac, ibuprofen, naproxen, ketoprofen, fenoprofen, flurbiprofen, mefenamic acid, meclof enamic acid, flufenamic acid, niflumic acid, and where in the ester group R can be a sugar (amongst which aldose, or ketose pentose, or esose selected from a group of D- and L-enantioiuers of ribose, glucose, galactose, mannose, arabinose, xilose, allose, altrose, gulose, idose and talose and substituted derivatives thereof, such as glucosamine, galactosamine, N-acetyl glucosamine, N-acetyl galactosamine, N-acetyl ribosamine), a disaccharide, a trisaccharide or an oligosaccharide. | 09-01-2011 |
Annalisa Curcio, Torre Annunziata IT
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20090098208 | PHARMACEUTICAL COMPOSITIONS BASED ON POROUS ZEOLITES AS RELEASE MEANS OF PHARMACOLOGICALLY ACTIVE MOLECULES AND RELATIVE USE - The present invention relates to pharmaceutical compositions for the oral administration of pharmacologically active molecules, comprising a release means consisting of porous zeolite in powder form, incorporating pharmacologically active molecules inside the pores and/or on its surface, the relative use for the preparation of drugs for oral administration, in particular for the treatment of inflammatory pathologies at an intestinal level and the preparation process of these compositions. | 04-16-2009 |
Claudia Curcio, Torino IT
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20100192240 | REGULATION OF EXPRESSION OF PI3KBETA PROTEIN IN TUMORS - The present invention concerns the use of PI3Kβ protein and/or encoding gene for the screening for substances useful in the treatment of cancers, preferably breast cancers. The present invention also concerns a method for the diagnosis of malignant cell growth comprising the measuring the expression of PI3Kβ gene. The invention concerns also non-human transgenic animals as model study for human pathologies, preferably breast cancer, being transgenic for having altered PI3Kβ and Neu-T expression. | 07-29-2010 |
Claudio Curcio, Nola (na) IT
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20120268340 | Aperiodic and Non-Planar Array of Electromagnetic Scatterers, and Reflectarray Antenna Comprising the Same - The application discloses a one or two dimensional array of electromagnetic scatterers n scatterers (ED), whereby the aforementioned scatterers (ED) are arranged aperiodically on a curved line or surface (S). Further, the application describes a reflectarray antenna comprising at least one such array of electromagnetic scatters (ED) and at least one receiving and/or transmitting feed (F), cooperating with said array to generate an antenna beam A method for designing and manufacturing said array and said antenna is explained. The method optimizes in a several stages all degrees of freedom in order improve the performance of reflectarrays, increase the flexibility thereof and/or the conformity thereof with design specifications (radio pattern) and/or allowing said specifications to be satisfied with a smaller number of scatters. | 10-25-2012 |
Francesco Curcio, Udine IT
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20160083682 | Unitary 3D Culture Device - A continuous device for culturing mammalian cells in a three-dimensional structure for the transplantation or implantation in vivo is described. The culturing device comprises (a) a scaffold formed by a matrix of interconnected growth surfaces spaced at regular intervals and (b) a fluid distribution means at the inlet and the exit of the growth areas. The device is particularly useful for culturing bone cells for dental implants or bone reconstruction. | 03-24-2016 |
20160108358 | METHOD OF ASSEMBLING A 3D TISSUE CULTURING SCAFFOLD - A continuous device for culturing mammalian cells in a three-dimensional structure for the transplantation or implantation in vivo is described. The culturing device comprises (a) a scaffold formed by a matrix of interconnected growth surfaces spaced at regular intervals and (b) a fluid distribution means at the inlet and the exit of the growth areas. The device is particularly useful for culturing bone cells for dental implants or bone reconstruction. | 04-21-2016 |
Francesco Curcio, Pagnacco IT
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20100248248 | Use of the Serological Assay of the Cytokine B-Lymphocyte Stimulator (Blys) as a Prognostic and Monitoring Test for Immune-Related Transfusion Reactions - The use for the serum quantification of the cytokine B-Lymphocyte Stimulator (BLyS) for the evaluation of the risk of immunization and transfusion reactions after blood transfusion, and for the monitoring of patients undergoing blood transfusion or re-transfusion in a patient that includes an initial step of taking a sample of blood from the patient, a step of analyzing the blood sample to determine the concentration of cytokine BLyS, a step of comparing the BLyS levels determined in the previous step and one or more reference values of concentration of cytokine BLyS, a step of identifying a significant deviation between the determined concentration of cytokine BLyS and the reference values of concentration of cytokine BLyS indicated in the previous step and a step of assigning a risk and/or therapeutic effectiveness with respect to the immune-mediated transfusion reactions mentioned above, based on the previous steps. | 09-30-2010 |
20130034898 | CONTINUOUS CULTURING DEVICE - A continuous device for culturing mammalian cells in a three-dimensional structure for the transplantation or implantation in vivo is described. The culturing device comprises (a) a scaffold formed by a matrix of interconnected growth surfaces spaced at regular intervals and (b) a fluid distribution means at the inlet and the exit of the growth areas. The device is particularly useful for culturing bone cells for dental implants or bone reconstruction. | 02-07-2013 |
Francesco Curcio, Udine (ud) IT
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20140080154 | IMMUNODIAGNOSTIC METHOD FOR DIAGNOSING AUTO-IMMUNE SYSTEMIC SCLEROSIS (SSC) AND SYSTEMIC LUPUS ERYTHEMATOSUS (SLE) - The invention relates to a method for the identification of patients affected by Systemic Sclerosis (SSc) (early, limited cutaneous, diffuse forms) or Systemic Lupus Erythematosus (SLE). Among SSc and SLE patients, this method allows identification of presence of vascular ulcerations in SSc, and Raynaud's phenomenon in SLE, respectively. | 03-20-2014 |
Francesco Curcio, Pagnacco (ud) IT
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20140178448 | CONTINUOUS CULTURING DEVICE - A continuous device for culturing mammalian cells in a three-dimensional structure for the transplantation or implantation in vivo is described. The culturing device comprises (a) a scaffold formed by a matrix of interconnected growth surfaces spaced at regular intervals and (b) a fluid distribution means at the inlet and the exit of the growth areas. The device is particularly useful for culturing bone cells for dental implants or bone reconstruction. | 06-26-2014 |
Maria Curcio, Saluggia (vercelli) IT
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20100216376 | PROCESS FOR PRODUCING A STENT FOR ANGIOPLASTY - A stent has surface sculpturing, preferably on its outer surface only, having, for example, microspheres, having the function of increasing the actual geometric surface area of the stent, of creating undercuts and roughness to encourage the application of coatings of active or activatable agents, as well as of improving the attachment of the stent to the blood vessel wall. | 08-26-2010 |
20110066228 | CARRIER AND KIT FOR INTRALUMINAL DELIVERY OF ACTIVE PRINCIPLES OR AGENTS - A carrier for delivering at least one active principle at an intraluminal site. The carrier includes a carrier body, such as a stent. The carrier body is provided with one or more reservoirs. The reservoirs contain nanoparticles which convey at least one active principle. The nanoparticles also comprise a substance having characteristics of preferential affinity attraction to a desired region at the intraluminal site. The nanoparticles can migrate toward the preferred region. | 03-17-2011 |
20120323312 | STENT FOR ENDOLUMINAL DELIVERY OF ACTIVE PRINCIPLES OR AGENTS - The present invention provides a stent for implantation at a site within a human or animal body comprising: an expandable body having an inner surface and an outer surface; and treatment agents applied to the outer surface of the expandable body, the treatment agents comprising a combination of Paclitaxel and FK506 or their derivatives or analogues. | 12-20-2012 |
20130280315 | COMPOSITION FOR ACTIVE PRINCIPLES DELIVERY BY IMPLANT DEVICES - Composition for delivery of at least one active principle at the implantation site of an implant device, including: at least one active principle, and at least a first excipient combined with the at least one active principle, wherein the at least a first excipient is selected among fatty acids with a linear or branched, saturated chain, including a number of carbon atoms between 14 and 36. | 10-24-2013 |
Mario Curcio, Sins CH
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20090016932 | Micro Chamber - A microfluidic device is provided including at least one chamber accessible by microfiuidic channels characterized in that the surface of the channels and the chambers are patterned and comprise hydrophilic and hydrophobic areas. The surface energy in correspondence of the areas, i.e., the capillary force, being such that a liquid can be guided along the hydrophilic path, enter the chamber from one side, wet part of one surface of the chamber as a thin layer without touching the opposite surface of the chamber, thus avoiding to fill the volume inside the chamber in correspondence of the hydrophilic pattern until a second liquid, either sequentially or in parallel, comes to wet part of the opposite surface of the chamber and eventually touches the first liquid layer, resulting in a sudden coalescence and efficient mixing between the liquids. | 01-15-2009 |
20100091273 | Reference Light Source Device - The present invention relates to a system for the optical detection of light from analytical samples, the system comprising an analytical instrument comprising an optical detection unit and a sample block unit for receiving a plurality of analytical samples, the system further comprising a calibration device for calibrating the optical detection unit of the analytical instrument, wherein the calibration device comprises a substrate and at least one electrically powered reference light source coupled to the substrate, said at least one reference light source emitting light being detected by the optical detection unit. | 04-15-2010 |
20110124128 | Centrifugal Force Based Microfluidic System And Method For The Automated Analysis of Samples - Centrifugal force based microfluidic systems for the automated analysis of fluids involving the use of magnetically responsive particles and methods thereof are disclosed. A magnet is fixed to a supporting device of the system in correspondence to a retention zone of the system so as to rotate therewith and to generate a magnetic field which magnetically manipulates the magnetically responsive particles contained in a reaction chamber of the system. | 05-26-2011 |