Patent application number | Description | Published |
20080278710 | Integrated Optical Vapor Cell Apparatus for Precision Spectroscopy - An optical waveguide is provided comprising a non-solid core layer surrounded by a solid-state material, wherein light can be transmitted with low loss through the non-solid core layer. A vapor reservoir is in communication with the optical waveguide. One implementation of the invention employs a monolithically integrated vapor cell, e.g., an alkali vapor cell, using anti-resonant reflecting optical waveguides, or ARROW waveguides, on a substrate. | 11-13-2008 |
20110253295 | Integrated Optical Vapor Cell Apparatus for Precision Spectroscopy - An optical waveguide is provided comprising a non-solid core layer surrounded by a solid-state material, wherein light can be transmitted with low loss through the non-solid core layer. A vapor reservoir is in communication with the optical waveguide. One implementation of the invention employs a monolithically integrated vapor cell, e.g., an alkali vapor cell, using anti-resonant reflecting optical waveguides, or ARROW waveguides, on a substrate. | 10-20-2011 |
20130199701 | Integrated Optical Vapor Cell Apparatus for Precision Spectroscopy - An optical waveguide is provided comprising a non-solid core layer surrounded by a solid-state material, wherein light can be transmitted with low loss through the non-solid core layer. A vapor reservoir is in communication with the optical waveguide. One implementation of the invention employs a monolithically integrated vapor cell, e.g., an alkali vapor cell, using anti-resonant reflecting optical waveguides, or ARROW waveguides, on a substrate. | 08-08-2013 |
20130244227 | METHOD FOR AMPLIFICATION-FREE NUCLEIC ACID DETECTION ON OPTOFLUIDIC CHIPS - An optofluidic platform is constructed so as to comprise a planar, liquid-core integrated optical waveguides for specific detection of nucleic acids. Most preferably, the optical waveguides comprises antiresonant reflecting optical waveguide (ARROWs). A liquid solution can be prepared and introduced into the optofluidic platform for optical excitation. The resulting optical signal can be collected at the edges of the optofluidic platform and can be analyzed to determine the existence of a single and/or a specific nucleic acid. | 09-19-2013 |
20140111800 | HYBRID, PLANAR OPTOFLUIDIC INTEGRATION - An optofluidic platform is constructed to comprise a vertical integration of optical and fluidic layers. The optical layer enables interaction of light with a fluid for a variety of purposes, including particle detection, manipulation, and analysis. The vertical integration allows layers to be permanently or temporarily attached to each other. Temporary attachments provide the advantage of reusing the same optical layer with different fluidic layers. Most preferably, the optical layer comprises antiresonant reflecting optical waveguide. Further, a fluidic layer can be configured to act as an interface between the optical layer and other fluidic layers attached thereon. Moreover, the fluidic layers can be configured to perform fluidic functions. The optofluidic platform can also comprise a protective layer. As such, a liquid solution can be introduced in the optofluidic platform and single particles contained therein can be optically detected with extremely high sensitivity and without the need for advanced microscopy equipment. | 04-24-2014 |
20140313510 | MULTIPLEX FLUORESCENT PARTICLE DETECTION USING SPATIALLY DISTRIBUTED EXCITATION - A chip-scale optical approach to performing multi-target detection is based on molecular biosensing using fiber-optic based fluorescence or light scattering detection in liquid-core waveguides. Multiplexing methods are capable of registering individual nucleic acids and other optically responsive particles, and are ideal for amplification-free detection in combination with the single molecule sensitivity of optofluidic chips. This approach overcomes a critical barrier to introducing a new integrated technology for amplification-free molecular diagnostic detection. Specific examples of liquid-core optical waveguides and multi-mode interferometers are described; however, they can be implemented in a number of different ways as long as a series of excitation spots is created whose spacing varies with the excitation wavelength. | 10-23-2014 |
Patent application number | Description | Published |
20110021101 | MODIFIED STARCH BASED BINDER - An aqueous binder composition is provided that includes a modified starch and a silane coupling agent, and optionally, a crosslinking agent. The starch from which the modified starch is derived is natural in origin, biorenewable, and is derived from plant sources. The modified starch has been chemically modified from its natural form and may have a degree of polymerization from about 20 to about 4000. Additionally, the modified starches have a low viscosity and cure at moderate temperatures. Advantageously, the modified starches are water dispersible and have excellent resistance to water after curing. In addition, the binder has a light color after being cured. The crosslinking agent may be any compound suitable for crosslinking the starch based compound. In exemplary embodiments, the silane coupling agent is an aminosilane. The environmentally friendly, biorenewable binder may be used in the formation of insulation materials and non-woven chopped strand mats. | 01-27-2011 |
20110086567 | BIO-BASED BINDERS FOR INSULATION AND NON-WOVEN MATS - An aqueous binder composition is provided that includes a carbohydrate and a crosslinking agent. In exemplary embodiments, the carbohydrate-based binder composition may also include a catalyst, a coupling agent, a process aid, a crosslinking density enhancer, an extender, a moisture resistant agent, a dedusting oil, a colorant, a corrosion inhibitor, a surfactant, a pH adjuster, and combinations thereof. The carbohydrate may be natural in origin and derived from renewable resources. Additionally, the carbohydrate polymer may have a dextrose equivalent (DE) number from 2 to 20. In at least one exemplary embodiment, the carbohydrate is a water-soluble polysaccharide such as dextrin or maltodextrin and the crosslinking agent is citric acid. Advantageously, the carbohydrates have a low viscosity and cure at moderate temperatures. The environmentally friendly, formaldehyde-free binder may be used in the formation of insulation materials and non-woven chopped strand mats. A method of making fibrous insulation products is also provided. | 04-14-2011 |
20110223364 | INSULATIVE PRODUCTS HAVING BIO-BASED BINDERS - Fibrous insulation products have an aqueous binder composition that includes a carbohydrate and a crosslinking agent. In exemplary embodiments, the carbohydrate-based binder composition may also include a catalyst, a coupling agent, a process aid, a crosslinking density enhancer, an extender, a moisture resistant agent, a dedusting oil, a colorant, a corrosion inhibitor, a surfactant, a pH adjuster, and combinations thereof. The carbohydrate may be natural in origin and derived from renewable resources. Additionally, the carbohydrate polymer may have a dextrose equivalent (DE) number from 2 to 20. In at least one exemplary embodiment, the carbohydrate is a water-soluble polysaccharide such as dextrin or maltodextrin and the crosslinking agent is citric acid. Advantageously, the carbohydrates have a low viscosity and cure at moderate temperatures. The environmentally friendly, formaldehyde-free binder may be used in the formation of insulation materials and non-woven chopped strand mats. A method of making fibrous insulation products is also provided. | 09-15-2011 |
20120146252 | CONTROL METHOD FOR DETERMINING CURE STATUS OF GLASS FIBER PRODUCTS - A method for assessing the cure status of a fibrous blanket manufactured with mineral fibers and binder is disclosed and comprises a first, qualitative assessment of cure followed by a second quantitative assessment that utilizes one of alternative procedures depending on the outcome of the first, qualitative assessment. For example, a first visual inspection may qualitatively reveal areas or undercure, upon which a second pH test of samples extracted from undercured areas may quantify the degree of undercure. Conversely, if the visual inspection reveals no undercured areas, a different sampling procedure examines different blanket areas for overcure status using a similar pH test. | 06-14-2012 |
20130334726 | Use of Surfactants To Improve Aged Properties of Fiberglass Insulation Products - Fibrous insulation products manufactured with surfactants and methods for making are disclosed. The surfactant may be neutral or charged and, if charged, may be anionic, cationic or zwitterionic, although neutral or non-ionic provide suitable results. The surfactant may be of any chemical structure class, although ethoxylated alcohols and ethoxylated ethers have been found most suitable. Surfactant may be sprayed onto mineral fibers as a separate dispersion or as part of a binder dispersion. The surfactant my optionally be used with an organo-silane coupling agent, such as an amino-silane. | 12-19-2013 |
20140364029 | INSULATIVE PRODUCTS HAVING BIO-BASED BINDERS - Fibrous insulation products have an aqueous binder composition that includes a carbohydrate and a crosslinking agent. In exemplary embodiments, the carbohydrate-based binder composition may also include a catalyst, a coupling agent, a process aid, a crosslinking density enhancer, an extender, a moisture resistant agent, a deducting oil, a colorant, a corrosion inhibitor, a surfactant, a pH adjuster, and combinations thereof. The carbohydrate may be natural in origin and derived from renewable resources. Additionally, the carbohydrate polymer may have a dextrose equivalent (DE) number from 2 to 20. In at least one exemplary embodiment, the carbohydrate is a water-soluble polysaccharide such as dextrin or maltodextrin and the crosslinking agent is citric acid. Advantageously, the carbohydrates have a low viscosity and cure at moderate temperatures. The environmentally friendly, formaldehyde-free binder may be used in the formation of insulation materials and non-woven chopped strand mats. A method of making fibrous insulation products is also provided. | 12-11-2014 |
20150017858 | BIO-BASED BINDERS FOR INSULATION AND NON-WOVEN MATS - An aqueous binder composition is provided that includes a carbohydrate and a crosslinking agent. In exemplary embodiments, the carbohydrate-based binder composition may also include a catalyst, a coupling agent, a process aid, a crosslinking density enhancer, an extender, a moisture resistant agent, a dedusting oil, a colorant, a corrosion inhibitor, a surfactant, a pH adjuster, and combinations thereof. The carbohydrate may be natural in origin and derived from renewable resources. Additionally, the carbohydrate polymer may have a dextrose equivalent (DE) number from 2 to 20. In at least one exemplary embodiment, the carbohydrate is a water-soluble polysaccharide such as dextrin or maltodextrin and the crosslinking agent is citric acid. Advantageously, the carbohydrates have a low viscosity and cure at moderate temperatures. The environmentally friendly, formaldehyde-free binder may be used in the formation of insulation materials and non-woven chopped strand mats. A method of making fibrous insulation products is also provided. | 01-15-2015 |
20150033981 | BIO-BASED BINDERS FOR INSULATION AND NON-WOVEN MATS - An aqueous binder composition is provided that includes a carbohydrate and a crosslinking agent. In exemplary embodiments, the carbohydrate-based binder composition may also include a catalyst, a coupling agent, a process aid, a crosslinking density enhancer, an extender, a moisture resistant agent, a dedusting oil, a colorant, a corrosion inhibitor, a surfactant, a pH adjuster, and combinations thereof. The carbohydrate may be natural in origin and derived from renewable resources. Additionally, the carbohydrate polymer may have a dextrose equivalent (DE) number from 2 to 20. In at least one exemplary embodiment, the carbohydrate is a water-soluble polysaccharide such as dextrin or maltodextrin and the crosslinking agent is citric acid. Advantageously, the carbohydrates have a low viscosity and cure at moderate temperatures. The environmentally friendly, formaldehyde-free binder may be used in the formation of insulation materials and non-woven chopped strand mats. A method of making fibrous insulation products is also provided. | 02-05-2015 |
Patent application number | Description | Published |
20110003316 | LUMINESCENCE-BASED METHODS AND PROBES FOR MEASURING CYTOCHROME P450 ACTIVITY - The present invention provides methods, compositions, substrates, and kits useful for analyzing the metabolic activity in cells, tissue, and animals and for screening test compounds for their effect on cytochrome P450 activity. In particular, a one-step and two-step methods using luminogenic molecules, e.g. luciferin or coelenterazines, that are cytochrome P450 substrates and that are also bioluminescent enzyme, e.g., luciferase, pro-substrates are provided. Upon addition of the luciferin derivative or other luminogenic molecule into a P450 reaction, the P450 enzyme metabolizes the molecule into a bioluminescent enzyme substrate, e.g., luciferin and/or luciferin derivative metabolite, in a P450 reaction. The resulting metabolite(s) serves as a substrate of the bioluminescent enzyme, e.g., luciferase, in a second light-generating reaction. Luminescent cytochrome P450 assays with low background signals and high sensitivity are disclosed and isoform selectivity is demonstrated. The present invention also provides an improved method for performing luciferase reactions which employs added pyrophosphatase to remove inorganic pyrophosphate, a luciferase inhibitor which may be present in the reaction mixture as a contaminant or may be generated during the reaction. The present method further provides a method for stabilizing and prolonging the luminescent signal in a luciferase-based assay using luciferase stabilizing agents such as reversible luciferase inhibitors. | 01-06-2011 |
20110081670 | LUCIFERASE-BASED ASSAYS - A method and kit are provided for enhancing the tolerance of an assay reagent to compounds in an assay sample, the assay reagent including a luciferase enzyme. The method includes contacting the luciferase with a tolerance enhancement agent in an amount sufficient to substantially protect luciferase enzyme activity from interference of the compound and minimize interference by at least about 10% relative to an assay not having tolerance enhancement agent. | 04-07-2011 |
20130217051 | LUCIFERASE-BASED ASSAYS - A method and kit are provided for enhancing the tolerance of an assay reagent to compounds in an assay sample, the assay reagent including a luciferase enzyme. The method includes contacting the luciferase with a tolerance enhancement agent in an amount sufficient to substantially protect luciferase enzyme activity from interference of the compound and minimize interference by at least about 10% relative to an assay not having tolerance enhancement agent. | 08-22-2013 |
20130217052 | LUCIFERASE-BASED ASSAYS - A method and kit are provided for enhancing the tolerance of an assay reagent to compounds in an assay sample, the assay reagent including a luciferase enzyme. The method includes contacting the luciferase with a tolerance enhancement agent in an amount sufficient to substantially protect luciferase enzyme activity from interference of the compound and minize interference by at least about 10% relative to an assay not having tolerance enhancement agent. | 08-22-2013 |
20140154716 | LUMINOGENIC AND FLUOROGENIC COMPOUNDS AND METHODS TO DETECT MOLECULES OR CONDITIONS - A method to detect the presence or amount of at least one molecule in a sample which employs a derivative of luciferin or a derivative of a fluorophore is provided. Compounds and compositions for carrying out the methods of the invention are also provided. | 06-05-2014 |
20140380514 | LUMINESCENCE-BASED METHODS AND PROBES FOR MEASURING CYTOCHROME P450 ACTIVITY - The invention provides compounds, compositions, methods, substrates, and kits useful for analyzing the metabolic activity in cells, tissue, and animals and for screening test compounds for their effect on cytochrome P450 activity. In particular, a one-step and two-step methods using luminogenic molecules, e.g. luciferins or coelenterazines, that are cytochrome P450 substrates and that are also bioluminescent enzyme, e.g., luciferase, pro-substrates are provided. The present method further provides a method for stabilizing and prolonging the luminescent signal in a luciferase-based assay using luciferase stabilizing agents such as reversible luciferase inhibitors. | 12-25-2014 |
Patent application number | Description | Published |
20100152228 | PHARMACEUTICAL COMPOSITIONS AND METHODS FOR RELIEVING PAIN AND TREATING CENTRAL NERVOUS SYSTEM DISORDERS - Patients susceptible to or suffering from disorders, such as central nervous system disorders, which are characterized by an alteration in normal neurotransmitter release, such as dopamine release (e.g., Parkinsonism, Parkinson's Disease, Tourette's Syndrome, attention deficient disorder, or schizophrenia), are treated by administering a compound of Formulas 1 or 2, as described herein. The compounds of Formulas 1 and 2 are also useful for treating pain, and treating drug addiction, nicotine addiction, and/or obesity. The compounds can exist as individual stereoisomers, racemic mixtures, diastereomers and the like. | 06-17-2010 |
20100179183 | PHARMACEUTICAL COMPOSITIONS AND METHODS FOR RELIEVING PAIN AND TREATING CENTRAL NERVOUS SYSTEM DISORDERS - Patients susceptible to or suffering from disorders, such as central nervous system disorders, which are characterized by an alteration in normal neurotransmitter release, such as dopamine release (e.g., Parkinsonism, Parkinson's Disease, Tourette's Syndrome, attention deficient disorder, or schizophrenia), are treated by administering a compound of Formulas 1 or 2, as described herein. The compounds of Formulas 1 and 2 are also useful for treating pain, and treating drug addiction, nicotine addiction, and/or obesity. The compounds can exist as individual stereoisomers, racemic mixtures, diastereomers and the like. | 07-15-2010 |
Patent application number | Description | Published |
20090072745 | Lighting Fixture with EMI/RFI Electrically Conductive Shielding Grid - A lighting fixture for use in an environment which requires protection from EMI/RFI emissions. The fixture comprises a body forming a light-emitting opening, lighting components including at least one lamp in the body, a lens covering the opening, and a conductive grid across the opening, the grid being separate from the lens, electrically connected to the body, and positioned between the lighting components and the opening. | 03-19-2009 |
20120176792 | LED Luminaire Tertiary Optic System - A lens system for LED based light fixtures having a substantially coplanar array of LED's with a requirement for a wide angle of illumination. And in particular, light fixtures comprising LED lights used in low bay applications. | 07-12-2012 |
20120176797 | LED Luminaire Thermal Management System - A thermal management and heat transfer system for light fixtures. And in particular, light fixtures comprising LED lights requiring lower temperatures than those required by incandescent of neon based light fixtures. The heat transfer includes taking advantage of the thermal updrafts caused by free convection of waste heat to cool the fixture. | 07-12-2012 |
20130038770 | Sports Video Training Accessory - A system for providing feedback to an individual involved in improving an activity such as a sport, performance or the like. The present invention relates to a training accessory, and more particularly to a holding apparatus for mounting a video or photographic device, such as a digital camera having a display device for feedback, such as a tablet PC, i-phone, i-pad, cell phone having a screen, multimedia device, or the like. The imaging and display device being easily transportable and easy to set up, for example, on a golf course where multiple instances are required, yet does not interfere with the playing of the game. | 02-14-2013 |
Patent application number | Description | Published |
20090107835 | Rapidly Cleanable Electroplating Cup Assembly - Embodiments of a closed-contact electroplating cup assembly that may be rapidly cleaned while an electroplating system is on-line are disclosed. One disclosed embodiment comprises a cup assembly and a cone assembly, wherein the cup assembly comprises a cup bottom comprising an opening, a seal surrounding the opening, an electrical contact structure comprising a plurality of electrical contacts disposed around the opening, and an interior cup side that is tapered inwardly in along an axial direction of the cup from a cup top toward the cup bottom. | 04-30-2009 |
20090107836 | Closed Contact Electroplating Cup Assembly - Embodiments of a closed-contact electroplating cup are disclosed. One embodiment comprises a cup bottom comprising an opening, and a seal disposed on the cup bottom around the opening. The seal comprises a wafer-contacting peak located substantially at an inner edge of the seal. The embodiment also comprises an electrical contact structure disposed over a portion of the seal, wherein the electrical contact structure comprises an outer ring and a plurality of contacts extending inwardly from the outer ring, and wherein each contact has a generally flat wafer-contacting surface. The embodiment further comprises a wafer-centering mechanism configured to center a wafer in the cup. | 04-30-2009 |
20110181000 | RAPIDLY CLEANABLE ELECTROPLATING CUP SEAL - Embodiments of a closed-contact electroplating cup assembly that may be rapidly cleaned while an electroplating system is on-line are disclosed. One disclosed embodiment comprises a cup assembly and a cone assembly, wherein the cup assembly comprises a cup bottom comprising an opening, a seal surrounding the opening, an electrical contact structure comprising a plurality of electrical contacts disposed around the opening, and an interior cup side that is tapered inwardly in along an axial direction of the cup from a cup top toward the cup bottom. | 07-28-2011 |
20110233056 | ELECTROPLATING CUP ASSEMBLY - Embodiments of a closed-contact electroplating cup are disclosed. One embodiment comprises a cup bottom comprising an opening, and a seal disposed on the cup bottom around the opening. The seal comprises a wafer-contacting peak located substantially at an inner edge of the seal. The embodiment also comprises an electrical contact structure disposed over a portion of the seal, wherein the electrical contact structure comprises an outer ring and a plurality of contacts extending inwardly from the outer ring, and wherein each contact has a generally flat wafer-contacting surface. The embodiment further comprises a wafer-centering mechanism configured to center a wafer in the cup. | 09-29-2011 |
Patent application number | Description | Published |
20090054933 | INSTRUMENTS AND METHODS FOR TENSIONING A SPINAL TETHER - Various methods and devices are provided for tensioning a tether. In one embodiment, a tether tensioning device is provided and includes an elongate shaft adapted to be positioned adjacent to a bone anchor implanted in bone, and a tensioning mechanism pivotally associated with the elongate shaft and adapted to couple to a tether seated across the bone anchor and to pivot relative to the elongate shaft to apply a tensioning force to the tether. | 02-26-2009 |
20100241165 | LAMINOPLASTY METHODS USING HINGE DEVICE - A vertebra implant is provided that includes an elongate body with a first end configured to mate the first end to a first location on a vertebra, and a second end having at least one fastener configured to mate the second end to a second location on a vertebra. The elongate body also includes a deformable portion extending between the first and second ends that has an unexpanded configuration in which the deformable portion is configured to allow a tool to cut bone extending between the first and second ends when the first and second ends are mated to first and second locations on a vertebra, and an expanded configuration in which the deformable portion is deformed to increase a distance between the first and second ends such that a gap is created in the cut bone. The deformable portion is configured to maintain the first and second ends at a fixed distance apart when the deformable portion is in the expanded configuration. A vertebral implant is also provided that includes an elongate member configured to extend into a vertebra and form a hinge therein using a breakage point located along a length of the elongate member. | 09-23-2010 |
20100241230 | LAMINOPLASTY METHODS AND DEVICES - A vertebral implant is provided that includes a distraction member having a first end configured to pivotally couple to a first cut portion of a vertebra and a second end configured to mate with a base member configured to couple to a second cut portion of the vertebra. The distraction member can move relative to the base member to create a force effective to adjust a distance between the first and second cut portions of the vertebra. | 09-23-2010 |
20110046678 | Facet Joint Prosthesis - Various methods and devices are provided for a facet replacement device. In one embodiment of the invention, a facet replacement device is provided and includes an elongate member matable to a first vertebra and a housing. The housing can have a connector formed thereon and matable to an adjacent second vertebra and an inner lumen formed therein. The housing can also include a deformable member disposed within the inner lumen and having an opening formed therein for slidably receiving at least a portion of the elongate member such that the elongate member can be angularly oriented relative to a longitudinal axis of the lumen. | 02-24-2011 |
20120010662 | PEDICULAR FACET FUSION SCREW WITH PLATE - Spinal implants and methods for spinal stabilization and/or fusion are provided. Exemplary implants described herein can be configured for delivery to a facet joint to stabilize and/or fuse the facet joint, and can optionally be anchored within the pedicle for added fixation. The implant can optionally include a fusion-promoting bioactive material thereby providing a single device capable of spinal stabilization and/or fusion. Furthermore, a method of placing such an implant within a facet joint is provided. | 01-12-2012 |
20120010669 | PEDICULAR FACET FUSION SCREW WITH PLATE - Spinal implants and methods for spinal stabilization and/or fusion are provided. Exemplary implants described herein can be configured for delivery to a facet joint to stabilize and/or fuse the facet joint, and can optionally be anchored within the pedicle for added fixation. The implant can optionally include a fusion-promoting bioactive material thereby providing a single device capable of spinal stabilization and/or fusion. Furthermore, a method of placing such an implant within a facet joint is provided. | 01-12-2012 |
20130226249 | LAMINOPLASTY METHODS USING HINGE DEVICE - A vertebra implant is provided that includes an elongate body with a first end configured to mate the first end to a first location on a vertebra, and a second end having at least one fastener configured to mate the second end to a second location on a vertebra. The elongate body also includes a deformable portion extending between the first and second ends that has an unexpanded configuration in which the deformable portion is configured to allow a tool to cut bone extending between the first and second ends when the first and second ends are mated to first and second locations on a vertebra, and an expanded configuration in which the deformable portion is deformed to increase a distance between the first and second ends such that a gap is created in the cut bone. The deformable portion is configured to maintain the first and second ends at a fixed distance apart when the deformable portion is in the expanded configuration. A vertebral implant is also provided that includes an elongate member configured to extend into a vertebra and form a hinge therein using a breakage point located along a length of the elongate member. | 08-29-2013 |
20140012378 | Intervertebral Disc Prosthesis Having Multiple Bearing Surfaces - An intervertebral disc prosthesis comprises a left prosthesis component and a symmetric right prosthesis component positioned in an intervertebral space. Each prosthesis component includes a superior vertebra facing surface, an inferior vertebra facing surface, and a substantially spherical bearing surface. The bearing surface is positioned between the superior vertebra facing surface and the inferior vertebra facing surface. The superior vertebra facing surface is provided on a superior endplate and the inferior vertebra facing surface is provided on an inferior endplate. The superior endplate is operable to rotate relative to the inferior endplate upon the bearing surface. Each prosthesis component further comprises an elastic member positioned between an endplate and the bearing surface. The elastic member may be substantially cylindrical with a plurality of resilient ribs. Flexion/extension, lateral bending, and torsional movement are allowed by a combination of endplate rotation upon the bearing surface and compression of the elastic member. | 01-09-2014 |
20140188177 | PASSIVE SCREW LOCKING MECHANISM - Methods and devices are provided for passively locking a bone screw within a bone plate. In particular, the methods and devices allow a bone screw to be locked within a thru-hole in a bone plate without requiring any additional locking steps. In an exemplary embodiment, an annular feature is provided in a thru-hole of a bone plate, or in a bushing that is disposed within a thru-hole of a bone plate, for engaging a bone screw. The annular feature can be configured such that it allows the bone screw to be inserted through the thru-hole at various insertion angles while still being effective to prevent back-out of the bone screw, thereby locking the screw to the plate. | 07-03-2014 |
Patent application number | Description | Published |
20100080670 | Pipe handling apparatus - An elevator usable on a drilling rig is modified by attaching a swing arm and related structure to at least one accessory mounting provision on the elevator. The swing arm is tiltable to allow a single section elevator, carried by the swing arm, to engage a pipe extending near the well centerline. While the pipe section is being lifted, the swing arm pivots to allow the section to assume a vertical position under the elevator. When the pipe section is being rotated to run threads to join the section to the string the swing arm can extend to accommodate thread-run dimension changes. An elevator equivalent, without pipe gripping features, may be used. | 04-01-2010 |
20100163248 | Pipe handling apparatus - An arbor arranged for attachment to overhead support, such as a top drive or main rig hoist, is arranged to resiliently support a main body. The main body is arranged to support a wedge-lock type pipe gripper assembly on a second arbor that is resiliently supported by the main body. The two arbors are rotationally connected but only indirectly connected axially and, to a limited extent, can move independently. The actuator, or linear motor, that actuates the wedge-lock system has the ability to force release of the wedge-lock system when it has been set by massive pipe loads. The forced release actuation is independent of the load supporting features of the main body. Full range actuation of the main body and main arbor assembly length will not actuate the wedge-lock release system. The length of the overall assembly can be oscillated to vibrate a supported pipe string. | 07-01-2010 |
20100183418 | Pipe manipulating apparatus - An arbor, arranged for attachment to a drilling rigs overhead support and drilling fluid circuit, has a cross frame with axles that support telescoping link arms to carry a single stand elevator at their lower end. The link arms have provision, at their top end, to tilt about a horizontal axis. The link arms can extend an amount greater than their minimum length. | 07-22-2010 |
20100193197 | Pipe coupling torque control - A fluid powered pipe tong fluid supply has a shunt that fluidly connects the tong input fluid line to the tong output fluid line. A flow control valve is installed in the shunt and is open when pipe joint make-up begins. The valve is slowly closed and the resulting fluid power made available to the tong causes it to make the low-resistance turns required of the pipe during the thread run. As the valve continues to close, the resulting pipe turn increases the resistance and causes the tong motor to demand more pressure, to achieve more turn. Torque demand continues to develop as the valve continues to close. Options include computer control, a graph reader to direct the computer, a recorder, a manually set by-pass relief valve to parallel the flow control valve as a secondary pressure limit assurance. | 08-05-2010 |
20100218935 | Pipe Handling apparatus - An arbor arranged for attachment to overhead support, such as a top drive or main rig hoist, is arranged to resiliently support a main body. The main body is arranged to support a wedge-lock type pipe gripper assembly on a second arbor that is resiliently supported by the main body. The two arbors are rotationally connected but only indirectly connected axially and, to a limited extent, can move independently. The actuator, or linear motor, that actuates the wedge-lock system has the ability to force release of the wedge-lock system when it has been set by massive pipe loads. The forced release actuation is independent of the load supporting features of the main body. Full range actuation of the main body linear motor will not actuate the wedge-lock release system. | 09-02-2010 |
20110253361 | Fluid power conducting swivel - A casing running tool capable of handling pipe and tubing has fluid power conducting channels leading from stationary to rotating components, through a swivel. The swivel has a plurality of fluid channels, each confined by dynamic seals that rub peripherally on mating seal surfaces. The seals are carried on at least one piston that is movable, on command, to carry the seals out of contact with the peripherally rubbing surfaces. | 10-20-2011 |
Patent application number | Description | Published |
20090030421 | Implant engagement method and device - A method and system for engaging an implant with a bone is disclosed. In one method incorporating principles of the invention, a bone is engaged with an implant by placing a first surface of an implant adjacent to a first bone portion, contacting the first bone portion with at least one first engagement member extending from the first surface, controlling an agitator to agitate the first surface of the implant and the at least one first engagement member, generating at least one first surface feature in the first bone portion with the agitated at least one first engagement member, stilling the first surface implant and the at least one first engagement member and settling the stilled at least one first engagement member into engagement with the at least one first surface feature. | 01-29-2009 |
20090177284 | Intervertebral Disc - This invention relates to an intervertebral motion disc having two motion surfaces and. wherein the radius of the upper articulation surface of the core member is greater than the radius of the lower articulation surface of the core member, and wherein the first articulation surface of the core member is spherical and the second articulation surface of the core member is curved and non-spherical. | 07-09-2009 |
20120191197 | NUCLEUS AUGMENTATION DELIVERY DEVICE AND TECHNIQUE - A method of performing a procedure on an intervertebral disc includes inserting a cannulated delivery tube through an opening in an annulus fibrosus of the intervertebral disc, positioning an expandable portion of the tube within the opening in the annulus fibrosus, expanding the expandable portion into contact with the annulus fibrosus about the opening to create a seal between the expandable portion and the annulus fibrosus, performing a procedure through the cannulated delivery tube within the annulus fibrosis, removing the tube, and closing the opening in the annulus fibrosus. | 07-26-2012 |
20130261401 | Methods and Devices for Tissue Retraction - Methods and devices are provided for retracting tissue. In one exemplary embodiment, a retractor is provided that includes a base and a plurality of blades configured to removably and replaceably mate to the base. One or more of the plurality of blades can be configured to mate to the base in one of a plurality of available positions. In use, one or more adjustment mechanisms can be actuated to move one or more of the blades, thereby forming a pathway through tissue. The retractor can be formed from one or more radiolucent materials. | 10-03-2013 |
20130261402 | Methods and Devices for Tissue Retraction - Methods and devices are provided for retracting tissue. In one exemplary embodiment, a retractor is provided that includes a base, a plurality of blades extending from the base, and an actuator coupled to the base and operatively connected to the blades. The actuator can be configured to be actuated to move the blades relative to the base, thereby allowing the blades to retract tissue. The actuator can be self-locking so as to allow the blades to be freely movable within their entire range of motion relative to the base through actuation of the actuator without using another mechanism to lock the blades in a fixed position and to unlock the blades from the fixed position. The retractor can be formed from one or more radiolucent materials. | 10-03-2013 |
20140081323 | ANTI-BACKUP SUTURE ANCHOR - Devices and methods are provided herein that generally involve suture anchors having one or more anti-backup features configured to resist or prevent backward movement of a suture that is pulled through the suture anchor. In some embodiments, the suture anchor can be configured to permit a suture to slide freely in one direction but resist or prevent suture movement in the opposite direction. For example, cleats can be rotatably mounted within the suture anchor, can project radially outward from an exterior sidewall of the suture anchor, or can project circumferentially from sidewalls of one or more channels formed in the suture anchor's exterior surface. | 03-20-2014 |
Patent application number | Description | Published |
20100068199 | PCSK9 ANTAGONISTS - The present invention provides antagonizing antibodies, antigen-binding portions thereof, and aptamers that bind to proprotein convertase subtilisin kexin type 9 (PCSK9). Also provided are antibodies directed to peptides, in which the antibodies bind to PCSK9. The invention further provides a method of obtaining such antibodies and antibody-encoding nucleic acid. The invention further relates to therapeutic methods for use of these antibodies and antigen-binding portions thereof to reduce LDL-cholesterol levels and/or for the treatment and/or prevention of cardiovascular disease, including treatment of hypercholesterolemia. | 03-18-2010 |
20110052621 | PCSK9 VACCINE - The present invention relates to the provision of novel immunogens comprising an antigenic PCSK9 peptide linked to an immunogenic carrier for the prevention, treatment or alleviation of PCSK9-mediated disorders. The invention further relates to methods for production of these medicaments, immunogenic compositions and pharmaceutical compositing thereof and their use in medicine. | 03-03-2011 |
20120014951 | PCSK9 ANTAGONISTS - The present invention provides antagonizing antibodies, antigen-binding portions thereof, and aptamers that bind to proprotein convertase subtilisin kexin type 9 (PCSK9). Also provided are antibodies directed to peptides, in which the antibodies bind to PCSK9. The invention further provides a method of obtaining such antibodies and antibody-encoding nucleic acid. The invention further relates to therapeutic methods for use of these antibodies and antigen-binding portions thereof to reduce LDL-cholesterol levels and/or for the treatment and/or prevention of cardiovascular disease, including treatment of hypercholesterolemia. | 01-19-2012 |
20120015435 | PCSK9 ANTAGONISTS - The present invention provides antagonizing antibodies, antigen-binding portions thereof, and aptamers that bind to proprotein convertase subtilisin kexin type 9 (PCSK9). Also provided are antibodies directed to peptides, in which the antibodies bind to PCSK9. The invention further provides a method of obtaining such antibodies and antibody-encoding nucleic acid. The invention further relates to therapeutic methods for use of these antibodies and antigen-binding portions thereof to reduce LDL-cholesterol levels and/or for the treatment and/or prevention of cardiovascular disease, including treatment of hypercholesterolemia. | 01-19-2012 |
Patent application number | Description | Published |
20090245094 | OUTAGE ANALYSIS SYSTEM - A device may receiving alarms identifying failures of network elements, create a site table that includes a list of sites at which the alarms are generated and a number of alarms for each of the sites, determine whether an outage has occurred based on the alarms, analyze whether the outage is a false outage based on a failure of a probe that generates the alarms, and provide a notification that includes the site table, an indication of whether the outage has occurred, or an indication whether the outage is a false outage. | 10-01-2009 |
20100110883 | METHOD AND SYSTEM FOR DETERMINING ALTERNATE PATHS - An approach is provided for determining alternative paths. Information is stored specifying a set of available paths among network elements within a connection-oriented network. The available paths are sorted according to a predetermined criterion. The sorted paths are selectively filtered based on either a particular one of the network elements, a region associated with one or more of the network elements, or a combination thereof. | 05-06-2010 |
20110103371 | METHOD AND SYSTEM FOR PROVIDING SIGNALING GATEWAY MANAGEMENT - An approach is provided for signaling gateway management. Data from a plurality of signaling gateways corresponding to a plurality of trunks of a telecommunications network is automatically retrieved, each signaling gateway being configured to convert circuit-switched signaling to packet-switched signaling. The data is stored. An operating state for each of the plurality of trunks is determined based on the data to perform trending analysis for the operation of one or more of the plurality of trunks. | 05-05-2011 |
20120155297 | MEDIA GATEWAY HEALTH - Data is received from a media gateway relating to a congestion level in the media gateway. In a computer having a processor and a memory, at least a first datum and a second datum included in the data are evaluated. Based on the evaluation, it is determined whether the congestion level exceeds a predetermined level. The congestion level is reported, including whether the congestion level exceeds the predetermined level. | 06-21-2012 |
20120155455 | CALL ANALYSIS - A computer having a processor and a memory is configured to obtain a first set of data from a media gateway, the first set of data including a first trunk identifier and an identifier for a point code associated with the trunk. The computer is further configured to obtain a second set of data related to the media gateway from a call database, the second set of data including a second trunk identifier, and a release code. The computer is further configured to join the first set of data to the second set of data by matching the first trunk identifier to the second trunk identifier. The computer is further configured to determine a number of times that the release code corresponds to the point code. | 06-21-2012 |
20130329569 | OUTAGE ANALYSIS SYSTEM - A device may receiving alarms identifying failures of network elements, create a site table that includes a list of sites at which the alarms are generated and a number of alarms for each of the sites, determine whether an outage has occurred based on the alarms, analyze whether the outage is a false outage based on a failure of a probe that generates the alarms, and provide a notification that includes the site table, an indication of whether the outage has occurred, or an indication whether the outage is a false outage. | 12-12-2013 |
20140043963 | METHOD AND SYSTEM FOR DETERMINING ALTERNATE PATHS - An approach is provided for determining alternative paths. Information is stored specifying a set of available paths among network elements within a connection-oriented network. The available paths are sorted according to a predetermined criterion. The sorted paths are selectively filtered based on either a particular one of the network elements, a region associated with one or more of the network elements, or a combination thereof. | 02-13-2014 |
Patent application number | Description | Published |
20090147819 | CALIBRATION OF TEMPERATURE CONTROL SYSTEM FOR SEMICONDUCTOR PROCESSING CHAMBER - Methods and systems for calibrating a temperature control system in a vapor deposition chamber. A temperature sensor senses temperature within a semiconductor processing chamber and generates an output signal. A temperature control system controls a chamber temperature by controlling a heating apparatus based on the output signal. A method includes instructing the control system to target a setpoint temperature, and depositing a layer of material onto a surface in the chamber by a vapor deposition process. A variation of a property of the layer is measured while depositing the layer, the property known to vary cyclically as a thickness of the layer increases. The measured property is allowed to vary cyclically for one or more cycles. If there is a difference between a time period of one or more of the cycles and an expected time period associated with the setpoint temperature, the temperature control system is adjusted based on the difference. | 06-11-2009 |
20100012030 | Process for Deposition of Semiconductor Films - Chemical vapor deposition processes utilize chemical precursors that allow for the deposition of thin films to be conducted at or near the mass transport limited regime. The processes have high deposition rates yet produce more uniform films, both compositionally and in thickness, than films prepared using conventional chemical precursors. In preferred embodiments, a higher order silane is employed to deposit thin films containing silicon that are useful in the semiconductor industry in various applications such as transistor gate electrodes. | 01-21-2010 |
20100089314 | SUBSTRATE SUPPORT SYSTEM FOR REDUCED AUTODOPING AND BACKSIDE DEPOSITION - A substrate support system comprises a substrate holder having a plurality of passages extending between top and bottom surfaces thereof. The substrate holder supports a peripheral portion of the substrate backside so that a thin gap is formed between the substrate and the substrate holder. A hollow support member provides support to an underside of, and is configured to convey gas upward into one or more of the passages of, the substrate holder. The upwardly conveyed gas flows into the gap between the substrate and the substrate holder. Depending upon the embodiment, the gas then flows either outward and upward around the substrate edge (to inhibit backside deposition of reactant gases above the substrate) or downward through passages of the substrate holder, if any, that do not lead back into the hollow support member (to inhibit autodoping by sweeping out-diffused dopant atoms away from the substrate backside). | 04-15-2010 |
20100116207 | REACTION CHAMBER - A reaction chamber having a reaction spaced defined therein, wherein the reaction space is tunable to produce substantially stable and laminar flow of gases through the reaction space. The substantially stable and laminar flow is configured to improve the uniformity of deposition on substrates being processed within the reaction chamber to provide a predictable deposition profile. | 05-13-2010 |
20130109192 | SUSCEPTOR WITH RING TO LIMIT BACKSIDE DEPOSITION | 05-02-2013 |
Patent application number | Description | Published |
20080270183 | SYSTEMS AND METHODS FOR PRESENTATION OF CLINICAL EVIDENCE FOR DIAGNOSTIC INTERPRETATION - Certain embodiments of the present invention provide systems and methods for presentation of clinical evidence to a user. Certain embodiments provide an improved picture archiving and communication system (PACS) including a workflow manager facilitating presentation and diagnostic interpretation of clinical evidence aggregated from a plurality of sources. The PACS also includes a workflow screen including a plurality of presentation panes. Each of the plurality of presentation panes displays clinical evidence from the workflow manager according to a particular perspective. The plurality of presentation panes are independent but coordinated, and each of the plurality of presentation panes is context sensitive. | 10-30-2008 |
20090138318 | SYSTEMS AND METHODS FOR ADAPTIVE WORKFLOW AND RESOURCE PRIORITIZATION - Certain embodiments of the present invention provide systems and methods for adaptive workflow management in a clinical enterprise. Certain embodiments provide an adaptive clinical workflow management system. The system includes a workflow engine establishing a workflow based on a worklist including a plurality of tasks to be performed. The plurality of tasks are each assigned a priority and relating to patient care. The system also includes a resource monitor monitoring execution of the plurality of tasks in the worklist using one or more clinical resources to determine resource usage. The workflow engine adjusts the priority of tasks in the worklist based on changing system and network conditions to update the worklist and dynamically adjusts resource usage based on the updated worklist. | 05-28-2009 |
20090192823 | ELECTRONIC HEALTH RECORD TIMELINE AND THE HUMAN FIGURE - A patient information interface system presents an aggregated, graphical view of patient anatomy and history. The system includes a graphical representation of at least a portion of a human anatomy including one or more indicators, aggregated from a plurality of clinical information sources and located at anatomical locations on the representation, that correspond to clinical events that have occurred in connection with a patient. The system also includes an electronic health record timeline of clinical events for the patient. The timeline includes the same one or more indicators that are displayed on the graphical representation corresponding to clinical events that have occurred in connection with a patient. A selection or change of an indicator on one of the graphical representation or the electronic health record timeline triggers a corresponding selection or change of the indicator on the other of the graphical representation or the electronic health record timeline. | 07-30-2009 |
20100131292 | SYSTEMS AND METHODS FOR INTERRUPTION WORKFLOW MANAGEMENT - Certain embodiments of the present invention provide systems and methods for interruption workflow management in a clinical enterprise. Certain embodiments provide an interruption workflow management system for a clinical enterprise. The system includes a worklist including a plurality of patient indicators representing patients for which tasks are to be performed by a user. The system also includes a patient panel displaying patient information associated with a patient indicator selected from the worklist. The system further includes a patient indicator shelf holding one or more patient indicators from at least one of the worklist and the patient panel for later retrieval in response to user input. The patient indicator shelf facilitates restoration of a patient indicator from the patient indicator shelf to display in the patient panel in response to user input. | 05-27-2010 |
20140200925 | SYSTEMS AND METHODS FOR INTERUPPTION WORKFLOW MANAGEMENT - Certain embodiments of the present invention provide systems and methods for interruption workflow management in a clinical enterprise. Certain embodiments provide an interruption workflow management system for a clinical enterprise. The system includes a worklist including a plurality of patient indicators representing patients for which tasks are to be performed by a user. The system also includes a patient panel displaying patient information associated with a patient indicator selected from the worklist. The system further includes a patient indicator shelf holding one or more patient indicators from at least one of the worklist and the patient panel for later retrieval in response to user input. The patient indicator shelf facilitates restoration of a patient indicator from the patient indicator shelf to display in the patient panel in response to user input. | 07-17-2014 |
Patent application number | Description | Published |
20090325908 | 9-SUBSTITUTED MINOCYCLINE COMPOUNDS - The present invention pertains, at least in part, to novel 9-substituted minocycline compounds. These minocycline compounds can be used to treat numerous tetracycline compound-responsive states, such as bacterial infections and neoplasms, as well as other known applications for minocycline and tetracycline compounds in general, such as blocking tetracycline efflux and modulation of gene expression. | 12-31-2009 |
20100160263 | 7,9-SUBSTITUTED TETRACYCLINE COMPOUNDS - The present invention pertains to novel 7,9-substituted tetracycline compounds. These tetracycline compounds can be used to treat numerous tetracycline compound-responsive states, such as bacterial infections and neoplasms, as well as other known applications for minocycline and tetracycline compounds in general, such as blocking tetracycline efflux and modulation of gene expression. | 06-24-2010 |
20120283201 | 9-SUBSTITUTED MINOCYCLINE COMPOUNDS - The present invention pertains, at least in part, to novel 9-substituted minocycline compounds. These minocycline compounds can be used to treat numerous tetracycline compound-responsive states, such as bacterial infections and neoplasms, as well as other known applications for minocycline and tetracycline compounds in general, such as blocking tetracycline efflux and modulation of gene expression. | 11-08-2012 |
Patent application number | Description | Published |
20100148562 | CUSHION WITH PLURAL ZONES OF FOAM - A cushion assembly defining a thickness direction comprises at least one covering layer and a core layer. The core layer comprises a first member and a second member. The covering layer spans continuously across both the first and second members in a direction generally transverse to the thickness direction, and the first member is disposed adjacent a forward area of the cushion assembly. The second member is disposed adjacent a back surface of the first member. The second member has a higher resistance to resilient deformation than the first member, and the first member has a higher resistance to resilient deformation than the at least one covering layer. | 06-17-2010 |
20100251864 | Compressible Material Profile Forming Tooling, Profile Assembly With, and Method of Using Same - A tool device with projections and valley floors used in profiling material such as foam. The projections having distal recesses surrounded by rims to form flat topped products. A profiler has opposing tooling devices with one or more (e.g., stacked) tool devices and a cutter to form, for example, mirror image flat top output products including single of multi-zoned flat top surface regions with flat surface protuberances. Projections of one tooling device extend within a valley floor region surrounded by a projection of an opposing tooling device or within recesses formed in, for example, an opposing side wall of a projection of the opposing tooling device or projections designed to extend within valley floor regions between adjacent rows of projections on an opposing tooling device, inclusive of conformingly shaped valley floor regions having a common interior configuration to the exterior configuration of an opposing projection to be received. | 10-07-2010 |
20110067183 | CUSHIONING DEVICE AND METHOD OF MANUFACTURING - A cushioning device with an upper foam layer and a lower positioned foam layer, with the upper foam layer having multiple thickness zones defined by different height projections from one zone to another as to provide a thickness variation pattern, one side of the upper foam layer is less contoured when not yet assembled in the cushioning device and a second side is comprised of the multiple thickness zones such that, upon connection of the multiple thickness zones to the lower positioned foam layer, the height differential along a length of the upper foam layer is transmitted as to form a non-planar, crown configuration in the upper surface of the upper foam layer. A method includes roller contouring different height and shaped projection zones including zones with different ratios of peak height to overall zone height. | 03-24-2011 |
Patent application number | Description | Published |
20100189893 | CHEMICAL METHOD FOR SOIL IMPROVEMENT - A composition for chemical soil improvement includes a synthetic fluid or base oil, a pour point depressant, polyisobutylene, and synthetic fibers, and various combinations thereof. | 07-29-2010 |
20110229269 | Chemical Method for Soil Improvement - A method for providing soil improvement to a particulate surface soil including applying to and allowing to penetrate the associated surface soil a composition comprising a synthetic fluid and a binder and applying as a second surface a synthetic fluid, a binder, and synthetic fibers. | 09-22-2011 |
20110272626 | CHEMICAL METHOD AND COMPOSITION FOR SOIL IMPROVEMENT - A composition for chemical soil improvement includes a synthetic fluid or base oil, a pour point depressant, polyisobutylene, and synthetic fibers, and various combinations thereof. | 11-10-2011 |
20110272627 | CHEMICAL METHOD AND COMPOSITION FOR SOIL IMPROVEMENT - A composition for chemical soil improvement includes a synthetic fluid or base oil, a pour point depressant, polyisobutylene, and synthetic fibers, and various combinations thereof. | 11-10-2011 |
20130140486 | CHEMICAL METHOD AND COMPOSITION FOR SOIL IMPROVEMENT - A composition for chemical soil improvement includes a synthetic fluid or base oil, a pour point depressant, polyisobutylene, and synthetic fibers, and various combinations thereof. | 06-06-2013 |