Kim, KS
Dal-Young Kim, Manhattan, KS US
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20100136659 | Infectious cDNA Clone of North American Porcine Reproductive and Respiratory Syndrome (PPRS) Virus and Uses Thereof - The invention provides isolated polynucleotide molecules, including plasmids; viral vectors; and transfected host cells that comprise a DNA sequence encoding an infectious RNA sequence encoding a North American PRRS virus; and also North American PRRS viruses encoded thereby. The invention further provides isolated infectious RNA molecules encoding a North American PRRS virus. The invention also provides isolated polynucleotide molecules, infectious RNA molecules, viral vectors, and transfected host cells encoding genetically-modified North American PRRS viruses; and genetically-modified North American PRRS viruses encoded thereby. The invention also provides vaccines comprising such plasmids, RNA molecules, viral vectors, and North American PRRS viruses, and methods of using these vaccines in swine and in other animals. Also provided are isolated polynucleotide molecules, viral vectors, and transfected host cells that comprise a nucleotide sequence encoding a peptide of a North American PRRS virus. These viral vectors and transfected host cell lines are useful in providing peptides to compensate for mutated peptide coding sequences of DNA sequences encoding genetically-modified North American PRRS viruses so that functional virions can be generated. | 06-03-2010 |
20100215694 | Infectious cDNA of North American Porcine Reproductive and Respiratory Syndrome (PRRS) Virus and Uses Thereof - The invention provides isolated polynucleotide molecules that comprise a DNA sequence encoding an infectious RNA sequence encoding a genetically-modified North American PRRS virus, wherein the polynucleotide molecule lacks at least one detectable antigenic epitope of North American PRRS virus. The invention also provides vaccines comprising genetically modified North American PRRS virus, RNA molecules, plasmids and viral vectors comprising the isolated polynucleotide molecules. Also provided are isolated polynucleotide molecules further comprising at least one nucleotide sequence that encodes a detectable heterologous antigenic epitope, and vaccines comprising North American PRRS virus, RNA molecules, plasmids and viral vectors comprising such isolated polynucleotide molecules. | 08-26-2010 |
Euiho Kim, Overland Park, KS US
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20150054525 | METHOD AND APPARATUS FOR DISTANCE MEASURING EQUIPMENT (DME/NORMAL) USING A SMOOTHED CONCAVE POLYGONAL PULSE SHAPE - A method for measuring distance includes transmitting a first pair of RF pulses from an airborne interrogator, where the first pair of RF pulses are temporally separated from each other by a first time interval and each of the RF pulses in the first pair of RF pulses has a first pulse waveform. The method also includes receiving a second pair of RF pulses transmitted by a ground transponder. The RF pulses in the second pair of RF pulses have a second pulse waveform characterized by a smoothed concave polygonal function and/or a smoothed concave hexagonal function. The method further includes determining an elapsed time between transmitting the first pair of RF pulses and receiving the second pair of RF pulses and determining a distance between the airborne interrogator and the ground transponder based on at least the elapsed time. | 02-26-2015 |
20150054526 | METHOD AND APPARATUS FOR DISTANCE MEASURING EQUIPMENT (DME/NORMAL) USING ALTERNATIVE PULSE SHAPES - A method for measuring distance includes transmitting a first pair of RF pulses from an airborne interrogator, where the first pair of RF pulses are temporally separated from each other by a first time interval and each of the RF pulses in the first pair of RF pulses has a first pulse waveform. The method also includes receiving a second pair of RF pulses transmitted by a ground transponder. The RF pulses in the second pair of RF pulses have a second pulse waveform characterized by a filtered asymmetric Gaussian function or a smoothed trapezoidal function. The method further includes determining an elapsed time between transmitting the first pair of RF pulses and receiving the second pair of RF pulses and determining a distance between the airborne interrogator and the ground transponder based on at least the elapsed time. | 02-26-2015 |
Samuel S. Kim, Mission, KS US
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20160076982 | AUTOMATED VITRIFICATION DEVICE - The present application relates to devices for the vitrification of biological samples, including embryos, oocytes and biological tissues. Suitably, the devices are automated devices which require little if any operator intervention or sample handling, thereby reducing contamination, improving success rates and increasing efficiency. Also provided are methods of vitrifying a biological sample, suitably using the disclosed devices. | 03-17-2016 |
S. Samuel Kim, Mission, KS US
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20140335555 | AUTOMATED VITRIFICATION DEVICE - The present application relates to devices for the vitrification of biological samples, including embryos, oocytes and biological tissues. Suitably, the devices are automated devices which require little if any operator intervention or sample handling, thereby reducing contamination, improving success rates and increasing efficiency. Also provided are methods of vitrifying a biological sample, suitably using the disclosed devices. | 11-13-2014 |
Yunjeong Kim, Manhattan, KS US
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20140243341 | BROAD-SPECTRUM ANTIVIRALS AGAINST 3C OR 3C-LIKE PROTEASES OF PICORNAVIRUS-LIKE SUPERCLUSTER: PICORNAVIRUSES, CALICIVIRUSES AND CORONAVIRUSES - Antiviral protease inhibitors, including peptidyl aldehydes, peptidyl α-ketoamides, peptidyl bisulfite salts, and peptidyl heterocycles, are disclosed, along with related antiviral compounds, and methods of using the same to treat or prevent viral infection and disease. The compounds possess broad-spectrum activity against viruses that belong to the picornavirus-like supercluster, which include important human and animal pathogens including noroviruses, enteroviruses, poliovirus, foot-and-mouth disease virus, hepatitis A virus, human rhinovirus (cause of common cold), human coronavirus (another cause of common cold), transmissible gastroenteritis virus, murine hepatitis virus, feline infectious peritonitis virus, and severe acute respiratory syndrome coronavirus. | 08-28-2014 |
20150133368 | MACROCYCLIC AND PEPTIDOMIMETIC COMPOUNDS AS BROAD-SPECTRUM ANTIVIRALS AGAINST 3C OR 3C-LIKE PROTEASES OF PICORNAVIRUSES, CALICIVIRUSES AND CORONAVIRUSES - Antiviral protease inhibitors, including macrocylic transition state inhibitors and peptidomimetics are disclosed, along with related antiviral compounds, and methods of using the same to treat or prevent viral infection and disease. The compounds possess broad-spectrum activity against viruses that belong to the picornavirus-like supercluster, which include important human and animal pathogens including noroviruses, sapoviruses, enteroviruses, poliovirus, foot-and-mouth disease virus, hepatitis A virus, human rhinovirus (cause of common cold), human coronavirus (another cause of common cold), transmissible gastroenteritis virus, murine hepatitis virus, feline infectious peritonitis virus, and severe acute respiratory syndrome coronavirus. | 05-14-2015 |