Locke, CA
Andrew Locke, Trabuco Canyon, CA US
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20100213469 | ILLUMINATION DEVICE - An illumination device having a plurality of light emitting diodes is provided. The light emitting diode may include a plurality of semiconductor layers at least one of which has a light emitting surface which may include a rough surface pattern having a pre-determined pattern. The pre-determined pattern may include one or more impurity regions with each region having a recess for guiding current across the light emitting surface and maximizing the emission of light (i.e. light intensity) of the illumination device. Each recess may include a lower internal portion having a bottom contact point located on a bottom surface and an upper internal portion integrally connected to the lower internal portion by a plurality of center contact points. The gaps created between the center and bottom contact points in adjacent recesses may act as spark gaps allowing for the current to flow through the entire light emitting surface. | 08-26-2010 |
20100213483 | ILLUMINATION DEVICE - An illumination device having a plurality of light emitting diodes is provided. The light emitting diode may include a plurality of semiconductor layers at least one of which has a light emitting surface which may include a rough surface pattern having a pre-determined pattern. The pre-determined pattern may include one or more impurity regions with each region having a plurality of peaks and valleys for directing the flow of current and causing an increase in the emission of light to reflect outwards from the light emitting surface while decreasing light reflected into the light emitting surface and as a result reducing the dissipation of heat. The plurality of impurity regions may be arranged such that a checkered pattern or configuration is formed by alternating the direction of the peaks and valleys in each region. | 08-26-2010 |
20100213869 | ILLUMINATION DEVICE - An illumination device having one or more light emitting diodes is provided. The illumination device may include an alternate current to direct current converter, a current regulator for receiving an output of the alternate current to direct current converter and a light source, containing the one or more of light emitting diodes, for receiving the regulated current from the current regulator. The regulated current may be applied to the one or more light emitting diodes causing the light emitting diodes to illuminate. The one or more light emitting diodes may be connected in series and each light emitting diode may include a light emitting surface having rough surface pattern for maximizing the light intensity of the light emitting diodes while minimizing the heat dissipating from the light emitting diodes. | 08-26-2010 |
Antony J. Locke, Saratoga, CA US
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20150281846 | COMPACT AUDIO SPEAKER - A audio speaker includes two parallel magnetically permeable plates and a diaphragm movably supported parallel to and approximately equidistant from the plates by a surround. A magnet assembly is coupled to the two magnetically permeable plates and passes through an opening in the diaphragm. The magnet assembly includes two magnets that are coupled with two like poles adjacent the diaphragm. A voice coil is coupled around the opening in the diaphragm to move the diaphragm when an electrical current flows in the voice coil. A suspension ring may surround a portion of the magnet assembly with a first end sealed to the diaphragm and an opposing second end sealed to one of the two plates to separate a back volume from a front volume. Some embodiments include several magnetic assemblies passing through the diaphragm with a voice coil and a suspension ring for each magnet assembly. | 10-01-2015 |
Ian Locke, Mountain View, CA US
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20130254820 | Methods for Accessing Media Over the Internet - Systems and methods for delivering media over a network are provided. Multiple media assets are stored on a server, as well as a representation for at least one media asset. The representation of a media asset is delivered to a client. A client user request based on selection of a representation is received, and the represented media asset is delivered from the server in response to the client user request. | 09-26-2013 |
Jeffrey B. Locke, La Jolla, CA US
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20130102523 | THERAPEUTIC COMBINATION OF DAPTOMYCIN AND PROTEIN SYNTHESIS INHIBITOR ANTIBIOTIC, AND METHODS OF USE - A therapeutic combination comprises an antibacterially effective amount of daptomycin, and an amount of protein synthesis inhibitor antibiotic effective to prevent the development of daptomycin non-susceptibility in bacteria. Related combination therapies and methods are also included. | 04-25-2013 |
20130274174 | THERAPEUTIC COMBINATION OF DAPTOMYCIN AND PROTEIN SYNTHESIS INHIBITOR ANTIBIOTIC, AND METHODS OF USE - A therapeutic combination comprises an antibacterially effective amount of daptomycin, and an amount of protein synthesis inhibitor antibiotic effective to prevent the development of daptomycin non-susceptibility in bacteria. Related combination therapies and methods are also included. | 10-17-2013 |
Kenneth W. Locke, Carlsbad, CA US
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20100260755 | IBUDILAST AND IMMUNOMODULATORS COMBINATION - The invention contemplates methods and compositions for treating multiple sclerosis including the administration of a PDE inhibitor and at least one immunomodulator comprising mitoxantrone, natalizumab, fingolimod, laquinimod, cladribine, dimethylfumarate or a mixture comprising synthetic polypeptide analogs of myelin basic protein, including alanine, glutamic acid, lysine, and tyrosine amino acid residues, in a therapeutically effective amount. A preferred PDE inhibitor includes ibudilast. | 10-14-2010 |
20120214839 | TREATMENT OF PROGRESSIVE NEURODEGENERATIVE DISEASE WITH IBUDILAST - Compositions and methods for treating progressive neurodegenerative diseases, and their associated symptoms by administration of ibudilast (3-isobutyryl-2-isopropylpyrazolo[1,5-a]pyridine). | 08-23-2012 |
20130217718 | TREATMENT OF PROGRESSIVE NEURODEGERATIVE DISEASE WITH IBUDILAST - Compositions and methods for treating progressive neurodegenerative diseases, and their associated symptoms by administration of ibudilast (3-isobutyryl-2-isopropylpyrazolo[1,5-a]pyridine). | 08-22-2013 |
20140171463 | TREATMENT OF PROGRESSIVE NEURODEGENERATIVE DISEASE WITH IBUDILAST - Compositions and methods for treating progressive neurodegenerative diseases, and their associated symptoms by administration of ibudilast (3-isobutyryl-2-isopropylpyrazolo[1,5-a]pyridine). | 06-19-2014 |
Kenneth W. Locke, Beverly Hills, CA US
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20090062330 | TREATMENT OF PROGRESSIVE NEURODEGENERATIVE DISEASE WITH IBUDILAST - Compositions and methods for treating progressive neurodegenerative diseases, and their associated symptoms by administration of ibudilast (3-isobutyryl-2-isopropylpyrazolo[1,5-a]pyridine). | 03-05-2009 |
Kenneth Walter Locke, Carlsbad, CA US
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20080292698 | PHARMACEUTICAL COMPOSITIONS OF ISOLATED ORTHORHOMBIC CRYSTALLINE 4-[6-ACETYL-3-[3-(4-ACETYL-3-HYDROXY-2-PROPYLPHENYLTHIO)PROPOXY]-2-PROPYLPHENOXY]BUTYRIC ACID AND METHODS OF USE - A pharmaceutical composition comprising a compound of formula (1) in polymorphic crystalline Form A: | 11-27-2008 |
20100285074 | PHENOXYALKYLCARBOXYLIC ACID DERIVATIVES IN THE TREATMENT OF IRRITABLE BOWEL SYNDROME - A method of treating irritable bowel syndrome in a patient suffering therefrom comprising: administering an effective amount of a compound selected from compound 1, its metabolite 2 and pharmaceutically acceptable salts or prodrugs thereof: | 11-11-2010 |
20110130373 | METHODS FOR ADMINISTRATION AND FORMULATIONS FOR THE TREATMENT OF REGIONAL ADIPOSE TISSUE - Provided herein are pharmaceutical formulations, methods, and systems for treating regional fat deposits and fat-related conditions and indications. Methods comprise administering a pharmaceutical formulation consisting essentially of a long-acting beta-2 adrenergic receptor agonist, for example, salmeterol, suitable for subcutaneous administration. Methods further comprise administering a pharmaceutical formulation that is suitable for subcutaneous injection comprising: (a) a lipophilic long-acting selective beta-2 adrenergic receptor agonist and/or glucocorticosteroid, or a salt, optical isomer, racemate, solvate, or polymorph thereof; and (b) at least one subcutaneously acceptable inactive ingredient. | 06-02-2011 |
20110224176 | Lyophilized Cake Formulations - Provided herein are lyophilized cake forms of fluticasone, salmeterol, or a pharmaceutically acceptable salt or a combination thereof which provides room temperature stability for an extended period of time. Upon reconstitution with an acceptable solvent (e.g., a carrier or diluent), the reconstituted pharmaceutical or cosmetic formulation provides a sterile, non-suspension form suitable for parenteral injectable administration, including subcutaneous injection. | 09-15-2011 |
20120046257 | Methods for Administration and Formulations for the Treatment of Regional Adipose Tissue - Provided herein are pharmaceutical formulations, methods, and systems for treating regional fat deposits and fat-related conditions and indications. Methods comprise administering a pharmaceutical formulation consisting essentially of a long-acting beta-2 adrenergic receptor agonist, for example, salmeterol, suitable for subcutaneous administration. Methods further comprise administering a pharmaceutical formulation that is suitable for subcutaneous injection comprising: (a) a lipophilic long-acting selective beta-2 adrenergic receptor agonist and/or glucocorticosteroid, or a salt, optical isomer, racemate, solvate, or polymorph thereof; and (b) at least one subcutaneously acceptable inactive ingredient. | 02-23-2012 |
20120178819 | Selective, Lipophilic, and Long-Acting Beta Agonist Monotherapeutic Formulations and Methods for the Cosmetic Treatment of Adiposity and Contour Bulging - Provided herein are pharmaceutical and cosmetic formulations and methods for regional adiposity reduction and treatment of body contour defects such as abdominal bulging; comprising an injectable formulation, said formulation comprising: an active ingredient that consists essentially of an adipose tissue-reducing amount of one or more lipophilic long-acting selective beta-2 adrenergic receptor agonists, or salts, solvates, or polymorphs thereof; and one or more subcutaneously acceptable inactive ingredients. | 07-12-2012 |
20150328146 | METHODS FOR ADMINISTRATION AND FORMULATIONS FOR THE TREATMENT OF REGIONAL ADIPOSE TISSUE - Provided herein are pharmaceutical formulations, methods, and systems for treating regional fat deposits and fat-related conditions and indications. Methods comprise administering a pharmaceutical formulation comprising a long-acting beta-2 adrenergic receptor agonist, for example, salmeterol, suitable for subcutaneous administration. Formulations comprise a pharmaceutical formulation that is suitable for subcutaneous injection comprising: (a) a lipophilic long-acting selective beta-2 adrenergic receptor agonist, or a salt thereof; and (b) at least one subcutaneously acceptable inactive ingredient. | 11-19-2015 |
Kenneth Walter Locke, San Diego, CA US
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20160089346 | METHOD OF TREATMENT FOR BODY CONTOURING - Provided herein are methods involving body contouring applications including treatments to reduce subcutaneous fat. The methods include the determination of patient suitability for body contouring treatment by evaluating one or more patient assessments. In various implementations, a patient determined to be suitable for body contouring treatment is administered a composition comprising a beta-2 adrenergic receptor agonist to the region of the body comprising subcutaneous fat, such as the central abdominal or submental region. | 03-31-2016 |
Lynda Locke, Castro Valley, CA US
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20130342022 | INDUCTIVELY COUPLED PRODUCT DISPLAY - A product display apparatus is provided. The display has a forward face with at least one display element disposed thereon. The display element is activated in some way upon receiving power. An inductive receiving coil is located on a flap that is below the forward face. This inductive receiving coil receives power from an inductive transmission coil located in proximity to the display apparatus. The receiving coil provides power to the display element when the coil is in proximity to the transmission coil. This power is used to activate the display element, such as by, for example, illuminating it. | 12-26-2013 |
Matthew Locke, Cameron Park, CA US
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20130174026 | TECHNIQUES FOR PROVIDING A NATURAL LANGUAGE NARRATIVE - Various embodiments for providing a natural language narrative are described. Embodiments may include a summary engine that collects data about an event, and selects a template to narrate a story about the event. A template may include static text, slots for data from the event, and slots for dynamic word choice. Templates may be selected according to a story type and story “flavor.” Templates may also include conditions that determine a choice of the use of template sub-sections. Various aspects of the templates may be selected randomly, to create the impression that the story is human-generated. The stories may be published to a variety of locations and formats. Other embodiments are described and claimed. | 07-04-2013 |
20130321388 | LIVE EVENT INFORMATION REPORTING SYSTEM - A live event information reporting system is described. An apparatus may comprise a live event information reporting application operative on a processor circuit to provide user interfaces for reporting and viewing information reported for live events. The live event information reporting application may comprise a context information component operative to access context information associated with one or more live events; a reporting user interface component operative to display a live event reporting user interface, the live event reporting user interface configured to provide the context information and one or more event information elements corresponding to the one or more live events; and a live event information component operative to receive live event information associated with the one or more live events entered via the event information elements. Other embodiments are described and claimed. | 12-05-2013 |
Michael Locke, Santa Clara, CA US
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20090028267 | Rapid re-synchronization of communication channels - A method of synchronizing a receiver with a transmitter. The method includes determining number of bits, j, for adjusting a bit stream, where the bit stream is generated from n tones and is dividable into codewords having a codeword length of N bytes, and the number of bits for adjusting the bit stream is determined based upon n and N. The method includes detecting a loss of synchronization indication. In response to detection of the loss of synchronization indication, the method includes adjusting the bit stream by j bits. The method includes determining whether synchronization has been regained. When synchronization has not been regained, the method includes adjusting the bit stream again by j bits. When synchronization has been regained, the method includes terminating adjustment of the bit stream. | 01-29-2009 |
20090028268 | Variable power communications including rapid switching between coding constellations of various sizes - A method of varying the power output of a transmitter. The method includes providing bit-loading information associated with each tone of multiple tones, where the multiple tones include a first set of tones. The method also includes producing, for transmission, on the first set of tones a first set of constellation symbols based upon the bit-loading information. The method also includes producing a second set of constellation symbols for transmission, where there is a difference of n bits between the bit size of the second bit sequence constellation symbol on each tone of the second set of tones and the bit-loading information associated with each tone of the first set of tones, and where n is an integer greater than or equal to 0. | 01-29-2009 |
Michael E. Locke, Santa Clara, CA US
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20090022214 | Optimized Short Initialization After Low Power Mode for Digital Subscriber Line Communications - A digital subscriber line (DSL) system that provides fast exit from an idle state is disclosed. The system includes a central office (CO) modem for communicating with a customer premises equipment (CPE) modem. Prior to entry into a low-power or idle state for the DSL link between the CO modem and the CPE modem, seamless rate adaptation is performed in order to improve the operating margin from that used in full-on operation, for example by selecting a reduced data rate. Transmission parameters, including data rate, and bits and gains, and corresponding to the improved operating margin are stored at the modems. Upon executing short initialization to return from the idle state, the stored transmission parameters are more likely to be adequate to meet current channel conditions, so the exchange of transmission parameters during short initialization is more likely to be avoided. | 01-22-2009 |
Michael Eugene Locke, Santa Clara, CA US
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20140241384 | METHOD OF SYNCHRONIZING A COMMUNICATION SYSTEM - A method of synchronizing a time division duplex (TDD) multi-line, multi-carrier data communication system is provided. Synchronization is established using unique pseudo-random bit sequences (PRBS) from a common generator polynomial having different seed values. Due to low correlation of PRBS generated with different seed values, a remote unit can only synchronize to its intended signal effectively mitigating far-end and near-end crosstalk impact of large bandwidth very high speed digital subscriber lines (VDSL). | 08-28-2014 |
Mike Locke, Santa Clara, CA US
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20130083830 | Systems and Methods for Equalizing Retransmission Delays for Data Retransmission Over Bonded Modems - Embodiments of the present invention provide systems for incorporating bonding processors while avoiding bonding processor buffer overflow by initiating retransmission requests on all data lines whenever corrupted data is encountered on one data line. Initiating these “extra” retransmission requests equalizes retransmissions delays over all transmission lines, preventing the bonding processor from receiving excess data that cannot be reassembled until the retransmission request is processed. | 04-04-2013 |
Robert B. Locke, Sonoma, CA US
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20150287301 | Correlation of Sensory Inputs to Identify Unauthorized Persons - A networked system for managing a physical intrusion detection/alarm includes an upper tier of server devices, comprising: processor devices and memory in communication with the processor devices, a middle tier of gateway devices that are in communication with upper tier servers, and a lower level tier of devices that comprise fully functional nodes with at least some of the functional nodes including an application layer that execute routines to provide node functions, and a device to manage the lower tier of devices, the device instantiating a program manager that executes a state machine to control the application layer in each of the at least some of the functional nodes. | 10-08-2015 |
20160093184 | STORE INTELLIGENCE PLATFORM USING PROXIMITY SENSING | 03-31-2016 |
Robert M. Locke, San Clemente, CA US
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20120078080 | Remotely Controlled Catheter Insertion System - A system for remotely controlling the positioning within the body of a patient of an elongated medical device optionally having a control handle, comprises a robotic system and a remote controller configured to control the robotic device. The robotic system comprises a handle controller; a sled member coupled to the handle controller, the sled member being configured to position the medical device within the body of the patient; and a sled base configured to advance the sled member towards the body of a patient, the sled bed being coupled to a sterile barrier effective to maintain sterility inside the sled base. A medical device introducer is effective to guide the elongated medical device into a patient's body. | 03-29-2012 |