Cook, MA
Alonzo Cook, Cambridge, MA US
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20130155370 | SURFACE MODIFIED CONTACT LENSES - Medical devices having a wettable, biocompatible surface are described herein. Processes for producing such devices are also described. | 06-20-2013 |
20130158150 | MULTISTEP UV PROCESS TO CREATE SURFACE MODIFIED CONTACT LENSES - Medical devices having a wettable, biocompatible surface are described herein. Processes for producing such devices are also described. | 06-20-2013 |
Andrew Cook, Stow, MA US
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20150368229 | MODULATORS OF METHYL MODIFYING ENZYMES, COMPOSITIONS AND USES THEREOF - Agents for modulating methyl modifying enzymes, compositions and uses thereof are provided herein. | 12-24-2015 |
Andrew S. Cook, Stow, MA US
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20150259351 | MODULATORS OF METHYL MODIFYING ENZYMES, COMPOSITIONS AND USES THEREOF - Agents for modulating methyl modifying enzymes, compositions and uses thereof are provided herein. | 09-17-2015 |
20150376190 | MODULATORS OF METHYL MODIFYING ENZYMES, COMPOSITIONS AND USES THEREOF - Agents having the structural Formula (II) for modulating histone methyl modifying enzymes, compositions and uses thereof for instance as anti-cancer agents are provided herein. | 12-31-2015 |
Brian Cook, Somerville, MA US
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20090156427 | Bio-Sensing Nanodevice - The invention provides a bio-sensing nanodevice comprising: a stabilized biologically-derived G-protein coupled receptor—the olfactory receptor—on a support, a real time receptor-ligand binding detection method, an odorant delivery system and an odorant recognition program. The biologically-derived G-protein coupled receptor can be stabilized on nanotechnology using surfactant peptide. The said nanodevice provides a greater surface area for better precision and sensitivity to odorant detection. The invention further provides a microfluidic chip containing a stabilized biologically-derived G-protein coupled receptor—the olfactory receptor—immobilized on a support, and arranged in at least two dimensional microarray system. The invention also provides a method of delivering odorant comprising the step of manipulating the bubbles in complex microfluidic networks wherein the bubbles travel in a microfluidic channel carrying a variety of gas samples to a precise location on a chip. The invention further provides method of fabricating hOR17-4 olfactory receptor. | 06-18-2009 |
Brian P. Cook, Northboro, MA US
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20100062002 | Brain Endothelial Cell Expression Patterns - To gain a better understanding of brain tumor angiogenesis, new techniques for isolating brain endothelial cells (ECs) and evaluating gene expression patterns were developed. When transcripts from brain ECS derived from normal and malignant colorectal tissues were compared with transcripts from non-endothelial cells, genes predominantly expressed in the endothelium were identified. Comparison between normal- and tumor-derived endothelium revealed genes that were specifically elevated in tumor-associated brain endothelium. These results confirm that neoplastic and normal endothelium in human brains are distinct at the molecular level, and have significant implications for the development of anti-angiogenic therapies in the future. | 03-11-2010 |
20120308479 | Brain Endothelial Cell Expression Patterns - To gain a better understanding of brain tumor angiogenesis, new techniques for isolating brain endothelial cells (ECs) and evaluating gene expression patterns were developed. When transcripts from brain ECs derived from normal and malignant colorectal tissues were compared with transcripts from non-endothelial cells, genes predominantly expressed in the endothelium were identified. Comparison between normal- and tumor-derived endothelium revealed genes that were specifically elevated in tumor-associated brain endothelium. These results confirm that neoplastic and normal endothelium in human brains are distinct at the molecular level, and have significant implications for the development of anti-angiogenic therapies in the future. | 12-06-2012 |
Chad L. Cook, Uxbridge, MA US
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20110178915 | Trading Order Validation System and Method and High-Performance Trading Data Interface - A post-trade monitor receives feedback in the form of drop copy messages from an exchange server and validates orders placed with the exchange server by a sponsored access trading platform shortly after the orders have been placed. If a recently placed order is found to violate a rule or regulation, the monitor instructs the trading platform to change to a more restrictive trading mode, such as to cease placing all orders or certain types of orders, at least until certain parameters are met. A library provides an interface in a sponsored access trading platform between a client application program that generates proposed orders and an exchange server. The library provides pre-trade validation of the orders and sends only validated orders to the exchange server. A network enables monitors, trading platforms and libraries to share information about customers' trading activities and locally recalculate customer trading limits resulting from these trading activities. A low-latency interface between a customer server, such as a server that employs algorithmic trading methods to generate buy and sell orders for securities, and a brokerage server that validates such securities trading orders is optimized for handling the securities trading orders. The interface supports a trading command set specifically designed for orders from customer trading application programs, and the interface formats received trading commands into compact messages that are sent over a high-speed communication link to the brokerage server. The interface receives order acknowledgement messages and the like from the brokerage server and invokes callback routines in the customer trading application program to report status information. | 07-21-2011 |
20110196778 | High Performance Trading Data Interface and Trading Data Distribution Protocol - A network enables monitors, trading platforms and libraries to share information about customers' trading activities and locally recalculate customer trading limits resulting from these trading activities. A low-latency interface between a customer server, such as a server that employs algorithmic trading methods to generate buy and sell orders for securities, and a brokerage server that validates such securities trading orders is optimized for handling the securities trading orders. The interface supports a trading command set specifically designed for orders from customer trading application programs, and the interface formats received trading commands into compact messages that are sent over a high-speed communication link to the brokerage server. The interface receives order acknowledgement messages and the like from the brokerage server and invokes callback routines in the customer trading application program to report status information. | 08-11-2011 |
20130216236 | MANAGED OPTICAL COMPUTER NETWORK DEVICE - A managed optical communication network device selectively passes or blocks an optical signal from an input port to an output port, based on state of the device. The device state may be managed remotely by sending management commands, according to a communication protocol, to the device. The device may be remotely controlled to selectively cut off all optical communications between two nodes, such as between two computers, between a local area network and a router, or between a router and a wide area network. | 08-22-2013 |
20140025558 | Trading Control System that Shares Customer Trading Activity Data Among Plural Servers - A network enables a plurality of servers to share information about customers' trading activities and locally recalculate customer trading limits resulting from these trading activities. If a trading limit is exceeded, a server may automatically change to a less permissive trading mode, prevent an order being placed with the at least one exchange server and/or enter a trading mode in which orders that decrease account exposure are allowed and orders that increase account exposure are prevented. | 01-23-2014 |
20140108228 | Trading Order Validation System and Method and High-Performance Trading Data Interface - A post-trade monitor receives feedback in the form of drop copy messages from an exchange server and validates orders placed with the exchange server by a sponsored access trading platform shortly after the orders have been placed. If a recently placed order is found to violate a rule or regulation, the monitor instructs the trading platform to change to a more restrictive trading mode, such as to cease placing all orders or certain types of orders, at least until certain parameters are met. | 04-17-2014 |
Christopher C. Cook, Bedford, MA US
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20110181966 | SOI Lens Structure for Medical Probe - An optical probe for emitting and/or receiving light within a body comprises an optical fiber that transmits and/or receives an optical signal, a silicon optical bench including a fiber groove running longitudinally that holds an optical fiber termination of the optical fiber and a reflecting surface that optically couples an endface of the optical fiber termination to a lateral side of the optical bench. The fiber groove is fabricated using silicon anisotropic etching techniques. Some examples use a housing around the optical bench that is fabricated using LIGA or other electroforming technology. A method for forming lens structure is also described that comprises forming a refractive lens in a first layer of a composite wafer material, such as SOI (silicon on insulator) wafers and forming an optical port through a backside of the composite wafer material along an optical axis of the refractive lens. the refractive lens is preferably formed using grey-scale lithography and dry etching the first layer. | 07-28-2011 |
Colin W. Cook, Pepperell, MA US
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20090053331 | Hands and feet sanitizing system - A sanitizing system is provided which includes an antibacterial liquid composition formulated to sanitize and deodorize the hands, feet, and other areas of the body. The antibacterial liquid composition is adapted to be dispensed from a pump dispenser as a topical spray. | 02-26-2009 |
Craig Cook, Wayland, MA US
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20080246761 | Systems for hybrid geometric/volumetric representation of 3d objects - The invention provides a system for modeling three-dimensional objects using hybrid geometric/volumetric representation, wherein sharp edges are created by a geometric representation that is connected to the volumetric representation. The system creates, maintains, and updates the hybrid representation according to user input. The system also provides for conversion of the hybrid representation into either a wholly geometric representation or a wholly volumetric representation, as may be needed for output to a given device, such as a display device, a printer, and/or a fabricating device. | 10-09-2008 |
20080261165 | Systems for haptic design of dental restorations - The invention provides systems for integrated haptic design and fabrication of dental restorations that provide significant advantages over traditional practice and existing computer-based systems. The systems feature technical advances that result in significantly more streamlined, versatile, and efficient design and fabrication of dental restorations. Among these technical advances are the introduction of voxel-based models; the use of a combination of geometric representations such as voxels and NURBS representations; the automatic identification of an initial preparation (prep) line and an initial path of insertion; the ability of a user to intuitively, haptically adjust the initial prep line and/or the initial path of insertion; the automatic identification of occlusions and draft angle conflicts (e.g., undercuts); the haptic simulation and/or marking of occlusions and draft angle conflicts; and coordination between design output and rapid prototyping/milling and/or investment casting. | 10-23-2008 |
Daniel R. Cook, Worcester, MA US
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20150237995 | Assistive Apparatus For Hand Held Vessels or Items - The assistive apparatus for hand held vessels or items is a device worn on the hand to facilitate the holding of anything of weight and to reduce the need for gripping strength. The device is a length of flexible material with at least two loops; one at either end; such that the loops are worn over the thumb and the pinky or one or more other fingers. The flexible material hangs like a hammock and allows the weight of an object, such as a glass or tool, to rest on the skeletal structure of the hand rather than depending upon the mechanical gripping force exerted by fingers. The device has application to help individuals suffering from a weakened grip from an ailment, such as arthritis, or that are in professions that require holding heavy objects for extend periods of time. | 08-27-2015 |
Donald Cook, Waltham, MA US
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20090054411 | 4-ANILINOQUINOLINE-3-CARBOXAMIDES AS CSF-1R KINASE INHIBITORS - The invention relates to chemical compounds of formula IA or IB: | 02-26-2009 |
Donald J. Cook, Waltham, MA US
Patent application number | Description | Published |
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20100216791 | PYRIDINYLQUINAZOLINAMINE DERIVATIVES AND THEIR USE AS B-RAF INHIBITORS - The invention relates to chemical compounds of the formula (I) or pharmaceutically acceptable salts thereof, which possess B-Raf inhibitory activity and are accordingly useful for their anti cancer activity and thus in methods of treatment of the human or animal body. The invention also relates to processes for the manufacture of said chemical compounds, to pharmaceutical compositions containing them and to their use in the manufacture of medicaments of use in the production of an anti-cancer effect in a warm blooded animal such as man. | 08-26-2010 |
Eugene Cook, Everett, MA US
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20090317233 | ROTARY NANOTUBE BEARING STRUCTURE AND METHODS FOR MANUFACTURING AND USING THE SAME - In one embodiment, a rotary device includes a multiwall nanotube that extends substantially perpendicularly from a substrate. A rotor may be coupled to an outer wall of the multiwall nanotube, be spaced apart from the substrate, and be free to rotate around an elongate axis of the multiwall nanotube. | 12-24-2009 |
Eugene Cook, Melrose, MA US
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20130098866 | ROTARY NANOTUBE BEARING STRUCTURE AND METHODS FOR MANUFACTURING AND USING THE SAME - In one embodiment, a rotary device includes a multiwall nanotube that extends substantially perpendicularly from a substrate. A rotor may be coupled to an outer wall of the multiwall nanotube, be spaced apart from the substrate, and be free to rotate around an elongate axis of the multiwall nanotube. | 04-25-2013 |
Eugene H. Cook, Melrose, MA US
Patent application number | Description | Published |
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20150246808 | ROTARY NANOTUBE BEARING STRUCTURE AND METHODS FOR MANUFACTURING AND USING THE SAME - In one embodiment, a rotary device includes a multiwall nanotube that extends substantially perpendicularly from a substrate. A rotor may be coupled to an outer wall of the multiwall nanotube, be spaced apart from the substrate, and be free to rotate around an elongate axis of the multiwall nanotube. | 09-03-2015 |
20160091339 | CALIBRATION SYSTEMS AND METHODS FOR GYROSCOPES - Methods and apparatus for calibrating a gyroscope without rotating the instrument. In one example, a calibration method includes operating the gyroscope in a self-oscillation loop to generate x-axis and y-axis drive signals, adding forcing signals to the x-axis and y-axis drive signals to produce pick-off x-axis and y-axis signals, measuring the pick-off x-axis and y-axis signals to produce measurement data, determining a relative phase between the pick-off x-axis and y-axis signals, based on the measurement data and the relative phase, estimating parameters of the gyroscope, based on the measurement data and the estimated parameters, calculating estimated position signals to calibrate the gyroscope. | 03-31-2016 |
Fred C. Cook, Assonet, MA US
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20100282151 | MAST TRACK WITH EXTERNAL HEADBOARD CAR - Disclosed are luff extrusions that solve problems of batten chafing and friction locking. The inventive luff extrusions provide batten end receptacles with channels for headboard cars. The luff extrusions absorb the wind-generated compressive forces exerted by the battens on the batten pockets and eliminate the need for sail slides. | 11-11-2010 |
20100282152 | MEGA YACHT MAST TRACKING SYSTEM WITH ARTICULATING SAIL FEEDER - Disclosed is an articulating sail feeder that solves problems associated with furling and reefing sails on yachts, particularly large yachts. The inventive sail feeder includes hinge tracks arranged in articulating column that bends and rotates freely, but limits the axial twist of the sail as during furling and reefing. The inventive hinge tracks have a cross section that includes a batten end receptacle with channels for headboard cars. Hinge tracks with the inventive cross section absorb the wind-generated compressive forces exerted by the battens on the batten pockets, reducing chafing, and eliminate the need for sail slides, which would otherwise lock the sail in place during furling and reefing. | 11-11-2010 |
20100282154 | SECTIONALIZED MAST TRACK - Disclosed is a sectionalized mast track that solves problems associated with furling and reefing sails on yachts, particularly large yachts. The inventive mast track includes mast track sections that are secured to a mast with hinges. Securing pins connect the sections to each other such that all the sections pivot together along the centerline defined by hinges. The securing mechanisms also make it possible to remove a single mast track section at a time. Embodiments of the inventive mast track have a cross section that absorbs wind-generated compressive forces exerted by battens, reducing chafing, and eliminates the need for sail slides, which would otherwise lock the sail in place during furling and reefing. The inventive mast track may also be configured to couple to an articulating sail feeder that bends and rotates freely, but limits the axial twist of the sail as during furling and reefing. | 11-11-2010 |
Gary Cook, Westford, MA US
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20090306579 | DELIVERY OF CORTICOSTEROIDS THROUGH IONTOPHORESIS - Disclosed herein are formulations of dexamethasone or a prodrug thereof suitable for delivery by ocular iontophoresis and methods of use thereof. | 12-10-2009 |
20120283231 | Delivery Of Corticosteroids Through Iontophoresis - Disclosed herein are formulations of dexamethasone or a prodrug thereof suitable for delivery by ocular iontophoresis and methods of use thereof. | 11-08-2012 |
20140046242 | DELIVERY OF CORTICOSTEROIDS THROUGH IONTOPHORESIS - Disclosed herein are formulations of dexamethasone or a prodrug thereof suitable for delivery by ocular iontophoresis and methods of use thereof. | 02-13-2014 |
Gary M. Cook, Newton, MA US
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20110299217 | HEATED ELECTROSTATIC CHUCK INCLUDING MECHANICAL CLAMP CAPABILITY AT HIGH TEMPERATURE - An electrostatic clamp is provided, having a clamping plate, wherein a clamping surface of the clamping plate is configured to contact the workpiece. A voltage applied to one or more electrodes selectively electrostatically attracts the workpiece to the clamping surface. One or more auxiliary clamping members are further provided wherein the one or more auxiliary clamping members are configured to selectively secure at least a portion of the workpiece to the clamping surface. A temperature monitoring device configured to determine a temperature of the workpiece is provided, and a controller is configured to selectively clamp the workpiece to the clamping surface via a control of the voltage to the one or more electrodes and the one or more auxiliary clamping members, based, at least in part, on the temperature of the workpiece. | 12-08-2011 |
20110299218 | HEATED ANNULUS CHUCK - A clamping device and method is provided for securing first and second workpieces having different sizes to a clamping device and providing thermal conditioning thereto. An electrostatic clamping plate having a diameter associated with the first workpiece surrounds a central portion of the clamp. A non-electrostatic central portion provides a heater within the annulus, wherein the central portion has a diameter associated with the second workpiece. A workpiece carrier is provided, wherein the workpiece carrier is configured to hold the second workpiece above the heater, and wherein a diameter of the workpiece carrier is associated with the electrostatic clamping plate annulus. The annulus selectively electrostatically clamps the workpiece carrier or a circumferential portion of the first workpiece to its clamping surface, therein selectively maintaining a position of the first or second workpiece with respect to the annulus or non-electrostatic central portion. | 12-08-2011 |
Gary P. Cook, Westford, MA US
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20090149400 | ANTI-PROLIFERATIVE COMPOUNDS, COMPOSITIONS, AND METHODS OF USE THEREOF - Compounds and compositions of Formula I are described, useful as anti-proliferative agents, and in particular anti-HPV, | 06-11-2009 |
20090291922 | ANTI-PROLIFERATIVE COMPOUNDS, COMPOSITIONS, AND METHODS OF USE THEREOF - Compounds and compositions of Formula I are described, useful as anti-proliferative agents, and in particular anti-HPV, | 11-26-2009 |
20100143485 | Oxycontin controlled release formulations and methods of using same - The compositions disclosed herein are of use for the treatment of a wide variety of diseases. In particular, the compositions provide oxytocin and oxytocin analogs in sustained release formulations. In particular embodiments, the disclosed compositions concern oxytocin and oxytocin analogs, each of which may be associated with a biodegradable polymer and/or attached to a hydrophilic polymer. The methods include treatment of a wide variety of diseases and conditions. In particular, the methods include treatment of sexual dysfunction and disorders associated with repetitive behaviors, such as autism. The usefulness of the present invention is that the oxytocin, oxytocin analogs and mixtures thereof can be administered in a pharmaceutical formulation that increases their half-life and also provides for sustained release. | 06-10-2010 |
20120244192 | SUSTAINED RELEASE FORMULATIONS OF PEPTIDOMIMETIC DRUGS AND USES THEREOF - The invention provides sustained release formulations comprising a C5a receptor antagonist. In certain embodiments the sustained-release formulations include microparticles that comprise a complement C5aR antagonist and a biodegradable polymeric matrix. Methods of treatment comprising the sustained release formulations of the invention are also provided. | 09-27-2012 |
20150037429 | Controlled Release Microparticles - Formulations for controlled, sustained release of biologically active agents for the treatment of ocular disorders have been developed. These formulations are based on solid microparticles formed of the combination of biodegradable, synthetic polymers such as poly(lactic acid) (PLA), poly(glycolic acid) (PGA), and copolymers thereof. The microparticles are characterized by low burst levels and efficient drug loading and sustained release. | 02-05-2015 |
20150079179 | SUSTAINED RELEASE FORMULATIONS OF PEPTIDOMIMETIC DRUGS AND USES THEREOF - The invention provides sustained release formulations comprising a C5a receptor antagonist. In certain embodiments the sustained-release formulations include microparticles that comprise a complement C5aR antagonist and a biodegradable polymeric matrix. Methods of treatment comprising the sustained release formulations of the invention are also provided. | 03-19-2015 |
Gary Paul Cook, Westford, MA US
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20150342910 | PHARMACEUTICAL COMPOSITIONS - The invention relates to aqueous suspension pharmaceutical compositions of poorly water soluble drugs, wherein said drugs are selected from compounds of formula (I) (Formula (I)), wherein R | 12-03-2015 |
Gordon V. Cook, Acton, MA US
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20160112784 | SOUND VIBRATION EXCITATION ASSEMBLY FOR DISCRETE AREA SOUND-ABSORBING CEILING SURFACES, AND SOUND SYSTEM INCLUDING SUCH VIBRATION EXCITATION ASSEMBLY - A sound vibration excitation assembly, for producing direct field sound masking, paging and/or music, comprises a ceiling coupler configured to be coupled to a discrete area sound-absorbing ceiling surface comprising mineral fiber or fiberglass, and a vibration exciter that is both configured to be electrically coupled to one or more sources of an electrical sound signal and is coupled to the ceiling coupler to produce vibrations in the ceiling coupler in response to the electrical sound signal. Related sound systems and methods are provided. | 04-21-2016 |
Gregory Cook, Holliston, MA US
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20140098256 | AUTOMATED CAMERA ASSEMBLY WITH INFRARED DETECTOR CURTAIN - An automated camera assembly comprising a camera and a detector for triggering the camera, wherein the detector includes an adjustable field of view. The detector can include a sensor and a curtain for reducing a maximum field of view to an adjusted field of view. The curtain can include an opaque member movable relative to the sensor. The curtain can instead include a processor programmed to trigger the camera when the subject is within the adjusted field of view. The invention is also embodied in a method of adjusting a field of view of a detector. The method comprises detecting a first subject within a maximum field of view, triggering the camera after detecting the first subject within the maximum field of view, adjusting to an adjusted field of view, detecting a second subject within the adjusted field of view, and triggering the camera after detecting the second subject. | 04-10-2014 |
20150049200 | AUTOMATED CAMERA ASSEMBLY WITH INFRARED DETECTOR CURTAIN - The present invention provides an automated camera assembly comprising a camera (e.g., a digital camera) having a field of vision and a detector for detecting a subject and triggering the camera. The detector has an adjustable field of view and includes a sensor (e.g., an IR sensor) having a maximum field of view, and a curtain for reducing the maximum field of view to an adjusted field of view. The curtain comprises at least two sections (e.g., opaque members) coupled to move together from a first position corresponding with the maximum field of view to a second position corresponding with the adjusted field of view smaller than the maximum field of view. Movement of the curtain relative to the sensor can be linear, pivotal, radial, or any other suitable movement. | 02-19-2015 |
Gregory Steven Cook, Holliston, MA US
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20090308090 | COOLING METHOD AND APPARATUS - An apparatus and method to cool compressors, condensing coils, and similar devices. The compressor or condensing coil is cooled by the delivery of water, which may be ambient temperature or chilled. In one embodiment, the water is delivered to a mesh filter or screen via one or more mist spray nozzles. Water conduits may be integrated with the filter frame. The method to control the delivery of the water is designed to conserve water. The control circuit comprises a microcontroller device which contains programming that receives inputs, including but not limited to, outside ambient air temperature, condenser liquid line temperature, relative humidity and electric current, and uses said inputs to provide a stepwise level of control (“solenoid open time”) of water delivery commensurate with outside air temperature and relative humidity. | 12-17-2009 |
20130264048 | COOLING METHOD AND APPARATUS - An apparatus and method to cool compressors, condensing coils, and similar devices. The compressor or condensing coil is cooled by the delivery of water, which may be ambient temperature or chilled. In one embodiment, the water is delivered to a mesh filter or screen via one or more mist spray nozzles. Water conduits may be integrated with the filter frame. The method to control the delivery of the water is designed to conserve water. The control circuit comprises a microcontroller device which contains programming that receives inputs, including but not limited to, outside ambient air temperature, condenser liquid line temperature, relative humidity and electric current, and uses said inputs to provide a stepwise level of control (“solenoid open time”) of water delivery commensurate with outside air temperature and relative humidity. | 10-10-2013 |
Laura Cook, Arlington, MA US
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20130218628 | System And Method For Capital Budgeting And Cost Estimation - A system for generating cost estimates and budgets for construction/maintenance projects for a property(s) allowing a user to select cost database from which to select cost data for the performance of an action item. The different databases may correspond to different geographic locations and include labor, materials and equipment costs for the selected location. The system further provides for presenting a hierarchical listing of cost line items with a cost associated with the item and searchable by description or an item identification number. The system still further allows for a user to click on an individual action item and obtain line item cost information relating to the selected action item. | 08-22-2013 |
Michael J. Cook, Franklin, MA US
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20150135861 | PRE-COLUMN HEATING OF MOBILE PHASE SOLVENT IN CHROMATOGRAPHY SYSTEMS - An apparatus for heating a flowing fluid includes a tubing assembly, a heater block made of thermally conductive material, and a heater cartridge in thermal communication with the heater block. The heater cartridge is configured to provide heat to the heater block for transfer to fluid flowing through the tubing assembly. The apparatus also includes circuitry in electrical communication with the heater cartridge to control a temperature of the heater block by controlling operation of the heater cartridge. The heater block is die-cast about the tubing assembly. | 05-21-2015 |
Neil Cook, Cambridge, MA US
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20110295764 | GENERATING A LAYOUT OF PRODUCTS - Generating a product layout includes obtaining attributes of a retail location; correlating the attributes of the retail location to information relating to a product in order to determine whether the product is appropriate for the retail location; and if the product is appropriate for the retail location, generating a layout of the product within the retail location relative to like products according to one or more predefined rules. | 12-01-2011 |
Ralph W. Cook, Norfolk, MA US
Robert E. Cook, Wakefield, MA US
Patent application number | Description | Published |
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20120250446 | Fluid Dispensing System and Method for Concrete Mixer - System and method for dispensing liquids into concrete mixer drums, particularly suitable for use on concrete mix trucks, involve use of liquid admixtures nozzle that is separate from water conduit and water nozzle, the admixtures nozzle being aimed and focused to spray through drum opening with dispersion pattern substantially within air/concrete interface defined by minimal volume concrete contained within the drum; and the water conduit or nozzle having a dispersion pattern preferably whereby wash water hits a portion of the inner drum wall and a portion of the air/concrete interface defined by a maximum amount of concrete contained within the drum. In preferred embodiments, a check valve assembly is used to connect separate admixture and water lines, so that both admixture and water nozzles can be used simultaneously during purging operation. | 10-04-2012 |
Ron Cook, Groton, MA US
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20130033279 | Electromagnetic Test Enclosure - The present disclosure is directed to systems and methods for operating, designing, testing and verifying the performance of wireless communication devices. Specifically, the present systems and methods can reliably determine the operating behavior of wireless communication modules within electronic products and devices in a relatively inexpensive and compact testing cabinet, with useful electromagnetically isolating structure, that allows for scalable, multi-application and production line operation and testing and verification of electromagnetic equipment therein. | 02-07-2013 |
20140091874 | Composite Electromagnetic Isolation Filters - The present disclosure is directed to systems and methods for operating, designing, testing and verifying the performance of wireless communication devices. Specifically, the present systems and methods can passively attenuate unwanted electromagnetic interference (EMI) without degrading signal quality of predetermined frequency using a novel versatile module including a RF absorbing material in a composite medium surrounding the conducting signal lines. Utilizing varying permeability media, the present invention offer a robust platform to eliminate unwanted noise while maintaining a desirable control and power interfaces used for testing of wireless communication systems. | 04-03-2014 |
Shelby Cook, Foxboro, MA US
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20080234715 | Tissue Extraction and Collection Device - Methods and device for extracting and collecting tissue, which can be used for example in tissue engineering and grafting applications, are disclosed. In one embodiment, a device can include an outer tube. A rotatable shaft can be disposed within the outer tube can have a tissue harvesting tip formed on its distal end, the tissue harvesting tip being effective to excise tissue upon rotation thereof A tissue collection device can be included to receive and collected excised tissue, and the tissue collection device can indicate the amount of tissue collected therein. For example, the tissue collection device can include a straining element which collects excised tissue and an indicator by which to assess the amount of collected tissue. In some embodiments, the tissue collection device can translate to indicate the amount of collected tissue. In many cases, devices disclosed herein can include driving mechanisms that are adapted to drive a tissue harvesting tip such that the tip excises soft tissue, but stops when contacting bone (or soon after contacting bone). In some embodiments, the tissue harvesting tip can be effective to excise viable tissue samples, such that the samples can exhibit desirable proportions of viable cells. Further, in some embodiments, the tissue harvesting tips can excise a tissue sample with tissue particles falling in certain size ranges. | 09-25-2008 |
20110257557 | Tissue Extraction and Collection Device - Methods and device for extracting and collecting tissue, which can be used for example in tissue engineering and grafting applications, are disclosed. In one embodiment, a device can include an outer tube. A rotatable shaft can be disposed within the outer tube can have a tissue harvesting tip formed on its distal end, the tissue harvesting tip being effective to excise tissue upon rotation thereof. A tissue collection device can be included to receive and collected excised tissue, and the tissue collection device can indicate the amount of tissue collected therein. For example, the tissue collection device can include a straining element which collects excised tissue and an indicator by which to assess the amount of collected tissue. In some embodiments, the tissue collection device can translate to indicate the amount of collected tissue. In many cases, devices disclosed herein can include driving mechanisms that are adapted to drive a tissue harvesting tip such that the tip excises soft tissue, but stops when contacting bone (or soon after contacting bone). In some embodiments, the tissue harvesting tip can be effective to excise viable tissue samples, such that the samples can exhibit desirable proportions of viable cells. Further, in some embodiments, the tissue harvesting tips can excise a tissue sample with tissue particles falling in certain size ranges. | 10-20-2011 |
Shelby L. Cook, Mansfield, MA US
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20120184992 | BIOABSORBABLE SUTURE ANCHOR SYSTEM FOR USE IN SMALL JOINTS - A bioabsorbable suture anchor for anchoring soft tissue to a bone is provided. The suture anchor is configured to toggle and anchor itself inside a bone cavity of a small joint. The anchor comprises an elongate body defined by a longitudinal axis, a first, leading end and a second, trailing end. The elongate body also has two opposed surfaces between the first and second ends, and a plurality of sidewalls extending between the two opposed surfaces. Extending from one of the sidewalls is a flared portion that is formed on the second end of the elongate body. A suture channel extends between the two opposed surfaces. The suture channel is formed in the elongate body for passage of a suture strand therethrough, such that pulling on an attached suture strand effects toggling of the anchor inside a bone cavity. | 07-19-2012 |
Silas P. Cook, Cambridge, MA US
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20090071068 | Method for reducing flammable creosote and other organic deposits in fireboxes - A composition and method for creosote control in firebox flues burning solid fuels combines hydrophobic metal additives with a fire accelerant. According to certain embodiments, the compositions may inhibit corrosion of metal flues in addition to creosote deposits. When the metal salts are added to an accelerant at effective concentrations, the combination delivers the metal catalyst to the lining of the exhaust system upon combustion. As such, the metals are conveniently and efficiently transported up the flue. | 03-19-2009 |
Timothy A. Cook, Acton, MA US
Patent application number | Description | Published |
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20090098142 | Methods and compositions for treating and monitoring treatment of IL-13-associated disorders - Methods and compositions for treating and/or monitoring treatment of IL-13-associated disorders or conditions are disclosed. | 04-16-2009 |
Warren E. Cook, Upton, MA US
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20110077911 | MULTI-MEASUREMENT VORTEX FLOWMETER - Two-wire transmitters are described in which the required voltage that a control room must supply to the transmitter is lower at high current than at low current, thus freeing up more voltage for other uses, and in which a constant set of operating voltages may be maintained. A corrected pressure in a vortex flow meter may be determined that reflects the mass flow rate. Thus, the mass flow rate may be determined based on the corrected pressure reading and a measured volumetric flow rate. Density may be determined from pressure and temperature using a table containing error values based on a standard density determination and a relatively simple approximation. During operation of a flow meter, the stored error values may be linearly interpolated and the approximation may be computed to determine the density from the stored error value. | 03-31-2011 |
20130119964 | MULTI-MEASUREMENT VORTEX FLOWMETER - Two-wire transmitters are described in which the required voltage that a control room must supply to the transmitter is lower at high current than at low current, thus freeing up more voltage for other uses, and in which a constant set of operating voltages may be maintained. A corrected pressure in a vortex flow meter may be determined that reflects the mass flow rate. Thus, the mass flow rate may be determined based on the corrected pressure reading and a measured volumetric flow rate. Density may be determined from pressure and temperature using a table containing error values based on a standard density determination and a relatively simple approximation. During operation of a flow meter, the stored error values may be linearly interpolated and the approximation may be computed to determine the density from the stored error value. | 05-16-2013 |
20160041576 | MULTI-MEASUREMENT VORTEX FLOWMETER - Two-wire transmitters are described in which the required voltage that a control room must supply to the transmitter is lower at high current than at low current, thus freeing up more voltage for other uses, and in which a constant set of operating voltages may be maintained. A corrected pressure in a vortex flow meter may be determined that reflects the mass flow rate. Thus, the mass flow rate may be determined based on the corrected pressure reading and a measured volumetric flow rate. Density may be determined from pressure and temperature using a table containing error values based on a standard density determination and a relatively simple approximation. During operation of a flow meter, the stored error values may be linearly interpolated and the approximation may be computed to determine the density from the stored error value. | 02-11-2016 |