Song, PA
Benjamin Song, Audubon, PA US
Chi Hwa Song, Pennbel, PA US
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20140033462 | SCOURER HAVING A SHAPE-SUPPORTING BODY - Disclosed is a scourer ( | 02-06-2014 |
Chunshan Song, State College, PA US
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20080264254 | Novel sorbents and purification and bulk separation of gas streams - Porous-material-supported polymer sorbents and process for removal of undesirable gases such as H | 10-30-2008 |
20080265212 | Sulfur-tolerant and carbon-resistant catalysts - The invention relates to novel bimetallic and trimetallic catalysts, their manufacture and use in both steam reforming and oxidative steam reforming of liquid fuels such as jet fuels, diesel fuels and gasoline to produce synthesis gas and/or hydrogen for fuel cell applications. The invention further relates to manufacture of synthesis gas and/or hydrogen gas for chemicals synthesis and fuel processing. The catalysts have high sulfur tolerance and carbon resistance when used in steam reforming and/or oxidative steam reforming of heavy hydrocarbon fuels. | 10-30-2008 |
20090065400 | Oxidatively regenerable adsorbents for sulfur removal - Compositions and processes are disclosed for removing sulfur and sulfur compounds from hydrocarbon fuel feedstocks. The feedstock is contacted with a regenerable sorbent such as a compound of the formula Ti | 03-12-2009 |
Fengling Song, Pittsburgh, PA US
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20080274492 | Detection of platinum group metals with fluorophores via allylic oxidative insertion - A method of detecting platinum group metals in a sample is provided. The method comprises the step of contacting the sample with a fluorophore capable of undergoing allylic ether or allylic ester cleavage. The fluorophore has an oxygen-protected moiety, the protecting group having an allylic functionality. A reducing agent and optionally a solubilizer are also added to the sample. Very low levels of platinum group metals such as palladium and platinum can be detected in a sample. | 11-06-2008 |
20080275257 | Hydroxymethyl fluorescein derivatives for use as biological markers and dyes - Hydroxymethyl fluorescein derivatives are provided. The derivatives can be easily conjugated to other molecules, and are more permeable than other fluorescein derivatives. Methods of making the derivatives are also provided. | 11-06-2008 |
Janet Song, Audubon, PA US
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20100285469 | METHOD OF TUMOR SCREENING - A method for tumor screening using urine of a mammal, the method includes obtaining a total urine nucleic acid (e.g., DNA) from a urine sample of a mammal, extracting a high molecular weight urine nucleic acid (above 1000 bp) by contacting the total urine nucleic acid with an adsorbent in the presence of a buffer which promotes binding of the high molecular weight urine nucleic acid to the adsorbent, replacing the buffer which promotes binding of the high molecular weight urine nucleic acid with a buffer which promotes binding of the low molecular weight urine nucleic acid to the adsorbent, extracting the low molecular weight urine nucleic acid by contacting with the adsorbent, eluting the low molecular weight urine nucleic acid, and assaying the low molecular weight urine nucleic acid for a presence or absence of a gene sequence specific to a certain type of tumor. | 11-11-2010 |
20140335529 | METHOD OF TUMOR SCREENING - A method for tumor screening using urine of a mammal, the method includes obtaining a total urine nucleic acid (e.g., DNA) from a urine sample of a mammal, extracting a high molecular weight urine nucleic acid (above 1000 bp) by contacting the total urine nucleic acid with an adsorbent in the presence of a buffer which promotes binding of the high molecular weight urine nucleic acid to the adsorbent, replacing the buffer which promotes binding of the high molecular weight urine nucleic acid with a buffer which promotes binding of the low molecular weight urine nucleic acid to the adsorbent, extracting the low molecular weight urine nucleic acid by contacting with the adsorbent, eluting the low molecular weight urine nucleic acid, and assaying the low molecular weight urine nucleic acid for a presence or absence of a gene sequence specific to a certain type of tumor. | 11-13-2014 |
Jiangxuan Song, State College, PA US
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20140017569 | DOPED CARBON-SULFUR SPECIES NANOCOMPOSITE CATHODE FOR LI-S BATTERIES - We report a heteroatom-doped carbon framework that acts both as conductive network and polysulfide immobilizer for lithium-sulfur cathodes. The doped carbon forms chemical bonding with elemental sulfur and/or sulfur compound. This can significantly inhibit the diffusion of lithium polysulfides in the electrolyte, leading to high capacity retention and high coulombic efficiency. | 01-16-2014 |
Kijoung Song, King Of Prussia, PA US
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20090203012 | Metabolic Syndrome Genetics - A gene (and polymorphisms within it) was associated with multiple components of the metabolic syndrome. Methods of screening subjects to identify risk of metabolic syndrome and related conditions are described, as are methods of screening compounds to identify those that act on the gene product as a target for the treatment of these conditions. | 08-13-2009 |
Le Song, Chalfont, PA US
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20140284850 | Cross-Linked Organic Polymer Compositions and Methods for Controlling Cross-Linking Reaction Rate and of Modifying Same to Enhance Processability - The invention includes a cross-linking composition comprising a cross-linking compound and a cross-linking reaction additive selected from an organic acid and/or an acetate compound, wherein the cross-linking compound has the structure according to formula (IV): | 09-25-2014 |
20140316079 | Cross-Linked Organic Polymers For Use as Elastomers in High Temperature Applications - Methods are disclosed to prepare elastomeric materials by providing aromatic polymer(s) which is/are non-elastomeric at room temperature; cross-linking the aromatic polymer using a cross-linking compound to form a cross-linked aromatic polymer which is substantially cured; and heating the cross-linked aromatic polymer to a temperature at or above a glass transition temperature of the cross-linked aromatic polymer. Materials formed thereby and end products are also described which may be formed using the aromatic polymer cross-linking techniques to develop strong elastomeric materials for high temperature and/or harsh condition end applications. | 10-23-2014 |
Le Song, Quakertown, PA US
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20120114724 | ANTIMICROBIAL AGENT, METHOD OF PREPARING AN ANTIMICROBIAL AGENT AND ARTICLES COMPRISING THE SAME - The present disclosure is directed to method of preparing an antimicrobial agent comprising heating a dialdehyde polysaccharide. The method comprises subjecting a dialdehyde polysaccharide, such as a dialdehyde starch or a dialdehyde cellulose, to heating and/or sonication for a period of time. Also provided herein is an antimicrobial composition comprising the prepared dialdehyde polysaccharide. The antimicrobial composition is effective at killing microbial agents such as viruses and bacteria within a short period of time. | 05-10-2012 |
Le Song, North Wales, PA US
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20140323668 | CROSSLINKING COMPOUNDS FOR HIGH GLASS TRANSITION TEMPERATURE POLYMERS - A composition having a crosslinking compound that has the following structure (I) wherein R is OH, NH | 10-30-2014 |
Minghu Song, Chester Springs, PA US
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20100113447 | TRIAZOLE COMPOUNDS THAT MODULATE HSP90 ACTIVITY - The present invention relates to substituted triazole compounds and compositions comprising substituted triazole compounds. The invention further relates to methods of inhibiting the activity of Hsp90 in a subject in need thereof and methods for treating hyperproliferative disorders, such as cancer, in a subject in need thereof comprising administering to the subject a substituted triazole compound of the invention, or a pharmaceutical composition comprising such a compound. | 05-06-2010 |
20120101072 | TRIAZOLE COMPOUNDS THAT MODULATE HSP90 ACTIVITY - The present invention relates to substituted triazole compounds and compositions comprising substituted triazole compounds. The invention further relates to methods of inhibiting the activity of Hsp90 in a subject in need thereof and methods for treating hyperproliferative disorders, such as cancer, in a subject in need thereof comprising administering to the subject a substituted triazole compound of the invention, or a pharmaceutical composition comprising such a compound. | 04-26-2012 |
20130303493 | Triazole Compounds that Modulate HSP90 Activity - The present invention relates to substituted triazole compounds and compositions comprising substituted triazole compounds. The invention further relates to methods of inhibiting the activity of Hsp90 in a subject in need thereof and methods for treating hyperproliferative disorders, such as cancer, in a subject in need thereof comprising administering to the subject a substituted triazole compound of the invention, or a pharmaceutical composition comprising such a compound. | 11-14-2013 |
Min Kyu Song, Pittsburgh, PA US
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20110086676 | MULTI-PURPOSE PLASMONIC AMBIENT LIGHT SENSOR AND VISUAL RANGE PROXIMITY SENSOR - A visible wavelength range proximity sensor includes a visible light emitter with a peak wavelength in a visible wavelength range, and a plasmonic ambient light sensor, where a proximity sensing mode and an ambient light sensing mode are time multiplexed. | 04-14-2011 |
20120129269 | NANO-OPTIC FILTER ARRAY BASED SENSOR - A device such as a filter or reflector includes a conductive layer including a periodic pattern of elements. The elements have shapes and sizes configured such that a transmittance or reflectance spectrum of the conductive layer has a drop at a long-wavelength end. The elements have a period configured such that the spectrum has a dip at a Plasmon mode resonant wavelength. The spectrum further includes a peal- between the dip and the drop. | 05-24-2012 |
Nan Song, Pittsburgh, PA US
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20100331210 | METHODS AND SYSTEMS FOR EVALUATING THE SENSITIVITY OR RESISTANCE OF TUMOR SPECIMENS TO CHEMOTHERAPEUTIC AGENTS - The present invention provides methods, systems, and kits for evaluating the sensitivity and/or resistance of tumor specimens to one or a combination of chemotherapeutic agents. Particularly, the invention provides malignant cell gene signatures that are predictive of a tumor's response to candidate chemotherapeutic regimens. | 12-30-2010 |
20110129822 | MULTI DRUG RESPONSE MARKERS FOR BREAST CANCER CELLS - The present invention provides methods for preparing a gene expression profile of a breast cancer cell, tumor, or cell line, where the gene expression profile may be evaluated for one or more gene expression signatures indicative of multidrug resistance. The signature may be indicative of resistance to one or more chemotherapeutic agents selected from a Taxol (e.g., Docetaxel or Paclitaxel), an antibiotic (e.g., Doxorubicin or Epirubicin), an antimetabolite (e.g., Fluorouracil and/or Gemcitabine), and an alkylating agent (e.g., Cyclophosphamide). Generally, the gene expression profile contains the level of expression for a plurality of genes listed in FIGS. | 06-02-2011 |
20110130302 | BIOLOGICAL PATHWAYS ASSOCIATED WITH CHEMOTHERAPY OUTCOME FOR BREAST CANCER - The present invention provides methods for preparing drug response and/or resistance profiles for breast tumor specimens, or cells derived therefrom. The drug response and/or resistance profiles are useful for determining effective chemotherapeutic agents for treatment of the tumor or cell to thereby individualize patient therapy. In other aspects, the invention provides a method for identifying a pathway or gene expression signature indicative of a breast cancer cell's sensitivity to a chemotherapeutic agent, which is useful for identifying a population response rate, or patient sub-population likely to respond to the drug candidate. | 06-02-2011 |
20110238322 | METHODS OF SIMULATING CHEMOTHERAPY FOR A PATIENT - The present invention provides methods for predicting or modeling a chemotherapy outcome for a given patient The method produces chemoresponse data, and presents the chemoresponse data in a clinically meaningful context such that the data can be meaningfully interpreted and evaluated in a clinical context The method of the invention involves correlating in vitro chemoresponse results for a particular patient with historical treatment outcomes Where a population of historical outcomes are matched to the patient by one or more clinical variables and such outcomes are matched to a potential treatment by the in vitro efficacy of the agent received, a meaningful simulation of the potential treatment for the patient can be constructed Simulations, such as survival curves, for a plurality of potential treatments may be generated and compared to contrast the estimated outcomes for several potential treatments, thereby providing the information desirable to design an individualized treatment regimen. | 09-29-2011 |
20120214679 | METHODS AND SYSTEMS FOR EVALUATING THE SENSITIVITY OR RESISTANCE OF TUMOR SPECIMENS TO CHEMOTHERAPEUTIC AGENTS - The present invention provides methods, systems, and kits for evaluating the sensitivity and/or resistance of tumor specimens to one or a combination of chemotherapeutic agents. Particularly, the invention provides malignant cell gene signatures that are predictive of a tumor's response to candidate chemotherapeutic regimens. | 08-23-2012 |
20140072999 | METHODS OF SIMULATING CHEMOTHERAPY FOR A PATIENT - The present invention provides methods for predicting or modeling a chemotherapy outcome for a given patient, to assist physicians in the selection of chemotherapeutic agents for individualized cancer treatment. | 03-13-2014 |
Tao Song, Erie, PA US
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20100274269 | Single probe with disturber - A single probe percutaneous surgical instrument for de-bulking/removing thrombus/clog/calculi has an actuator assembly ( | 10-28-2010 |
20140107534 | APPARATUS AND METHODS FOR TRANSFERRING ULTRASONIC ENERGY TO A BODILY TISSUE - An apparatus includes a monolithically-constructed transmission member that defines a lumen along a longitudinal axis. The transmission member includes a first portion, a second portion, and a third portion. The first portion is configured to be coupled to an ultrasonic energy source. The second portion is configured to contact a bodily tissue to transfer ultrasonic energy from a first portion into the bodily tissue. The third portion is disposed between the first portion and the second portion and defines a cross-sectional moment of inertia that is less than at least one of a cross-sectional area moment of inertia of the first portion or a cross-sectional moment of inertia of the second portion. | 04-17-2014 |
20140128863 | SYSTEMS AND METHODS FOR CONTROLLING DELIVERY OF ULTRASONIC ENERGY TO A BODILY TISSUE - An apparatus includes a generator including a control module that is operably coupled to a power module. The power module is configured to produce an electronic signal to be received by an ultrasonic energy delivery assembly. The ultrasonic energy delivery assembly is characterized by a natural frequency, and the electronic signal is characterized by a frequency. The control module is configured to send a control signal to the power module to randomly vary the frequency of the electronic signal within a range defined at least in part by the natural frequency. | 05-08-2014 |
20140364775 | SYSTEMS AND METHODS FOR DELIVERING ULTRASONIC ENERGY TO A BODILY TISSUE - A coupler includes a first portion and a second portion, and defines a passageway configured to fixedly receive a proximal end portion of a transmission member. The first portion is configured to be coupled to an ultrasonic energy source. The coupler is configured to transfer at least a portion of an ultrasonic vibration produced by the ultrasonic energy source to the transmission member. Furthermore, the first portion and the second portion are collectively configured to adjust a resonant frequency of the transmission member to correspond to a vibrational frequency of the ultrasonic vibration produced by the ultrasonic energy source. In some embodiments, the portion of the ultrasonic vibration includes a linear component. In such embodiments, the first portion and the second portion are collectively configured to transform at least a portion of the linear component of the ultrasonic vibration into a torsional component within the transmission member. | 12-11-2014 |
Wei Song, Audubon, PA US
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20140155279 | Detection of a panel of urine DNA markers for HCC screening and disease management - Provided herein is a method for detecting the presence or absence of a cancer in a biological sample of an individual, by determining the level of mutation and methylation of one or more genes from a group of genes comprising TP53, CTNNB1, hTERT, RASSF1A, GSTP1, p16, p15 and SFRP-1. Also provided herein is an assay to detect p53 mutations suitable for DNA isolated from biological body fluid in order to screen cancer patients. | 06-05-2014 |
Wenchao Song, Rosemont, PA US
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20100263061 | Properdin Modulation of Alternative Pathway and Uses Thereof - This invention relates to selective activation of the alternative pathway (AP) using anti-Properdin antibodies. Specifically, the invention relates to methods for treating an AP complement-mediated pathology or AP mediated condition in a subject by contacting the subject with an anti-Properdin antibodies. Likewise, properdin knockout transgenic non-human mammals and their use are provided. | 10-14-2010 |
Wenchao Song, Bosemont, PA US
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20100119530 | Regulation of TLR Signaling by Complement - This invention provides methods of inducing the production of pro-inflammatory cytokines by activating Toll like Receptor (TLR) and the complement system. This invention further provides vaccines that contain compounds that activate a Toll like Receptor (TLR) and the complement system. | 05-13-2010 |
Wenchao Song, Bryn Mawr, PA US
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20140212427 | Anti-Properdin Antibodies and Uses Thereof - This invention relates to selective inhibition of the alternative pathway (AP) of the complement system using an anti-properdin antibody. Specifically, the invention relates to methods of treating an AP-mediated pathology or AP-mediated condition in an individual by contacting the individual with an anti-properdin antibody. | 07-31-2014 |
Wenliang Song, Philadelphia, PA US
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20100209962 | Tetranor PGDM: A Biomarker of PGD2 Synthesis In Vivo - The present invention relates to a prostaglandin D | 08-19-2010 |
20100285500 | NEUROFURANS-INDICES OF OXIDANT STRESS - The invention is drawn to a new class of isoeicosanoids that have been identified as products of the oxidation of docosahexaenoic acid (DHA). The invention provides compositions and methods related to the new class of molecules. | 11-11-2010 |
Xiaomin Song, Drexel Hill, PA US
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20120164066 | ANTIGEN-BINDING PROTEINS COMPRISING RECOMBINANT PROTEIN SCAFFOLDS - Disclosed herein are recombinant protein scaffolds and recombinant multifunctional protein scaffolds for use in producing antigen-binding proteins In addition, nucleic acids encoding such recombinant protein scaffolds, recombinant multifunctional protein scaffolds, and antigen-binding proteins are provided Vectors and cells useful for expression of the described proteins are also provided, as are methods of use. | 06-28-2012 |
20140234221 | ANTIGEN-BINDING PROTEINS COMPRISING RECOMBINANT PROTEIN SCAFFOLDS - Disclosed herein are recombinant protein scaffolds and recombinant multifunctional protein scaffolds for use in producing antigen-binding proteins In addition, nucleic acids encoding such recombinant protein scaffolds, recombinant multifunctional protein scaffolds, and antigen-binding proteins are provided Vectors and cells useful for expression of the described proteins are also provided, as are methods of use. | 08-21-2014 |
Xiao-Yu R. Song, West Chester, PA US
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20090137783 | CNGH0010 Specific Polynucleotides, Polypeptides, Antibodies, Compositions, Methods and Uses - Novel polypeptides (CNGH0010) and antibodies, including specified portions or variants, specific for at least one such CNGH0010 polypeptide, variant, or fragment thereof, as well as nucleic acids encoding such CNGH0010 polypeptides and antibodies, complementary nucleic acids, vectors, host cells, and methods of making and using thereof, are useful for therapeutic and diagnostic formulations, administration and devices. The aforesaid polypeptides can be used to generate human, primate, rodent, mammalian, chimeric, humanized and/or CDR-grafted anti-CNGH0010 antibodies. The CNGH0010 polypeptides and antibodies are used in modulating or treating at least one CNGH0010-related disease in a cell, tissue, organ, animal, or patient. Such diseases may include, but are not limited to, psoriasis, rheumatoid arthritis, emphysema, asthma, diabetes, autoimmune thyroiditis, inflammatory bowel diseases, including Crohn's disease and ulcerative colitis, different types of dermatitis including allergic dermatitis, contact dermatitis, actinic keratosis, wound healing, scar formation, various renal diseases, various respiratory diseases, various diseases of reproductive organs, such as endometriosis, melanoma, squamous cell carcinoma, ovarian cancer, breast cancer, lung cancer, colon cancer, prostate cancer, renal cell carcinoma, Grave's diseases and other inflammatory and hyperproliferative diseases. | 05-28-2009 |
20090239258 | Anti-IL-6 Antibody Nucleic Acid Molecules and Methods - Anti-IL-6 antibody nucleic acids, vectors, host cells, transgenic animals or plants, and methods of making and using thereof have applications in diagnostic and/or therapeutic compositions, methods and devices. | 09-24-2009 |
20110081355 | Methods of Diagnosing and Treating Conditions Using Anti-IL-6 Antibodies - Anti-IL-6 antibodies are used to treat IL-6 related conditions, such as rheumatoid arthritis, osteoarthritis, osteolysis, aseptic loosening of orthopedic implants, systemic lupus erythematosus, cutaneous lupus erythematosus, lupus nephritis, type 2 diabetes mellitus, chronic obstructive pulmonary disease, and renal cell carcinoma. | 04-07-2011 |
20120045453 | Anti-IL-6 Antibodies, Compositions, Methods and Uses - An anti-IL-6 antibody, including isolated nucleic acids that encode at least one anti-IL-6 antibody, vectors, host cells, transgenic animals or plants, and methods of making and using thereof have applications in diagnostic and/or therapeutic compositions, methods and devices. | 02-23-2012 |
20130017208 | Anti-IL-6 Antibodies, Compositions, Methods and Uses - An anti-IL-6 antibody, including isolated nucleic acids that encode at least one anti-IL-6 antibody, vectors, host cells, transgenic animals or plants, and methods of making and using thereof have applications in diagnostic and/or therapeutic compositions, methods and devices. | 01-17-2013 |
Yuan-Quan Song, Philadelphia, PA US
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20090055940 | ZEBRAFISH MODEL OF MLL LEUKEMOGENESIS - The zebrafish mll gene and methods of use thereof are provided. | 02-26-2009 |