Patent application number | Description | Published |
20100003246 | Novel heterocyclic compounds and uses therof - New substituted heterocyclic compounds, compositions containing them, and methods of using them for the inhibition of Raf kinase activity are provided. The new compounds and compositions may be used either alone or in combination with at least one additional agent for the treatment of a Raf kinase mediated disorder, such as cancer. | 01-07-2010 |
20100234394 | SUBSTITUTED BENZIMIDAZOLES AND METHODS OF THEIR USE - New substituted benzimidazole compounds, compositions, and methods of inhibition of kinase activity associated with tumorigenesis in a human or animal subject are provided. In certain embodiments, the compounds and compositions are effective to inhibit the activity of at least one serine/threonine kinase or receptor tyrosine kinase. The new compounds and compositions may be used either alone or in combination with at least one additional agent for the treatment of a serine/threonine kinase- or receptor tyrosine kinase-mediated disorder, such as cancer. | 09-16-2010 |
20120208815 | PIM KINASE INHIBITORS AND METHODS OF THEIR USE - New compounds, compositions and methods of inhibition of kinase activity associated with tumorigenesis in a human or animal subject are provided. In certain embodiments, the compounds and compositions are effective to inhibit the activity of at least one serine/threonine kinase or receptor tyrosine kinase. The new compounds and compositions may be used either alone or in combination with at least one additional agent for the treatment of a serine/threonine kinase- or receptor tyrosine kinase-mediated disorder, such as cancer. | 08-16-2012 |
20130210818 | Novel Heterocyclic Compounds and Uses Thereof - New substituted heterocyclic compounds, compositions containing them, and methods of using them for the inhibition of Raf kinase activity are provided. The new compounds and compositions may be used either alone or in combination with at least one additional agent for the treatment of a Raf kinase mediated disorder, such as cancer. | 08-15-2013 |
Patent application number | Description | Published |
20100004237 | 2-Amino-7,8-dihydro-6H-pyrido[4,3-D]pyrimidin-5-ones - Disclosed are 2-amino-7,8-dihydro-6H-pyrido[4,3-d]pyrimidin-5-one compounds, their stereoisomers, tautomers, pharmaceutically acceptable salts, and prodrugs thereof; compositions that include a pharmaceutically acceptable carrier and one or more of the 2-amino-7,8-dihydro-6H-pyrido[4,3-d]pyrimidin-5-one compounds, either alone or in combination with at least one additional therapeutic agent. Disclosed also are methods of using the 2-amino-7,8-dihydro-6H-pyrido[4,3-d]pyrimidin-5-one compounds, either alone or in combination with at least one additional therapeutic agent, in the prophylaxis or treatment of cellular proliferative, viral, autoimmune, cardiovascular, and central nervous system diseases. | 01-07-2010 |
20100184754 | QUINOLINONE DERIVATIVES - Organic compounds having the formulas I and II are provided where the variables have the values described herein. | 07-22-2010 |
Patent application number | Description | Published |
20100037739 | Power cutting tool with overhead sensing system - A power cutting tool, such as a table saw, comprising a sensing system for detecting certain conditions with respect to an exposed blade of the power cutting tool is disclosed. Several embodiments of the sensing system comprise at least one sensor located above the blade and positioned to (1) monitor one or more volume zones adjacent the blade, (2) detect when an object enters one or more of the zones, and (3) trigger a reaction system in response to the detection. Another embodiment uses an optical sensor to measure the height of objects approaching the blade to detect an increase in the height beyond a predetermined threshold. Still another embodiment uses an optical distance sensor to detect the occurrence of a work piece lifting from the table top which can indicate that a kick-back condition is imminent. The reaction system can be triggered when such a condition is detected. | 02-18-2010 |
20100261961 | HERMETICALLY SEALED DISTAL SENSOR ENDOSCOPE - In one embodiment, an endoscopic camera for a robotic surgical system includes a stereo camera module mounted to a robotic arm of a patient side cart. The optical and electro-optic components of the camera module are hermetically sealed within a first housing. Signals from an electro-optic component travel through traces in a ceramic substrate forming one side of the hermetically sealed first housing. A second housing surrounds the first housing and optical fibers are dispersed between the housings to provide lighting in a body cavity. The camera module may be sterilized by an autoclave. | 10-14-2010 |
20110224684 | ROBOTIC SURGERY SYSTEM INCLUDING POSITION SENSORS USING FIBER BRAGG GRATINGS - A surgical instrument is provided, including: at least one articulatable arm having a distal end, a proximal end, and at least one joint region disposed between the distal and proximal ends; an optical fiber bend sensor provided in the at least one joint region of the at least one articulatable arm; a detection system coupled to the optical fiber bend sensor, said detection system comprising a light source and a light detector for detecting light reflected by or transmitted through the optical fiber bend sensor to determine a position of at least one joint region of the at least one articulatable arm based on the detected light reflected by or transmitted through the optical fiber bend sensor; and a control system comprising a servo controller for effectuating movement of the arm. | 09-15-2011 |
20110224685 | ROBOTIC SURGERY SYSTEM INCLUDING POSITION SENSORS USING FIBER BRAGG GRATINGS - A surgical instrument is provided, including: at least one articulatable arm having a distal end, a proximal end, and at least one joint region disposed between the distal and proximal ends; an optical fiber bend sensor provided in the at least one joint region of the at least one articulatable arm; a detection system coupled to the optical fiber bend sensor, said detection system comprising a light source and a light detector for detecting light reflected by or transmitted through the optical fiber bend sensor to determine a position of at least one joint region of the at least one articulatable arm based on the detected light reflected by or transmitted through the optical fiber bend sensor; and a control system comprising a servo controller for effectuating movement of the arm. | 09-15-2011 |
20110224686 | ROBOTIC SURGERY SYSTEM INCLUDING POSITION SENSORS USING FIBER BRAGG GRATINGS - A surgical instrument is provided, including: at least one articulatable arm having a distal end, a proximal end, and at least one joint region disposed between the distal and proximal ends; an optical fiber bend sensor provided in the at least one joint region of the at least one articulatable arm; a detection system coupled to the optical fiber bend sensor, said detection system comprising a light source and a light detector for detecting light reflected by or transmitted through the optical fiber bend sensor to determine a position of at least one joint region of the at least one articulatable arm based on the detected light reflected by or transmitted through the optical fiber bend sensor; and a control system comprising a servo controller for effectuating movement of the arm. | 09-15-2011 |
20110224687 | ROBOTIC SURGERY SYSTEM INCLUDING POSITION SENSORS USING FIBER BRAGG GRATINGS - A surgical instrument is provided, including: at least one articulatable arm having a distal end, a proximal end, and at least one joint region disposed between the distal and proximal ends; an optical fiber bend sensor provided in the at least one joint region of the at least one articulatable arm; a detection system coupled to the optical fiber bend sensor, said detection system comprising a light source and a light detector for detecting light reflected by or transmitted through the optical fiber bend sensor to determine a position of at least one joint region of the at least one articulatable arm based on the detected light reflected by or transmitted through the optical fiber bend sensor; and a control system comprising a servo controller for effectuating movement of the arm. | 09-15-2011 |
20110224688 | ROBOTIC SURGERY SYSTEM INCLUDING POSITION SENSORS USING FIBER BRAGG GRATINGS - A surgical instrument is provided, including: at least one articulatable arm having a distal end, a proximal end, and at least one joint region disposed between the distal and proximal ends; an optical fiber bend sensor provided in the at least one joint region of the at least one articulatable arm; a detection system coupled to the optical fiber bend sensor, said detection system comprising a light source and a light detector for detecting light reflected by or transmitted through the optical fiber bend sensor to determine a position of at least one joint region of the at least one articulatable arm based on the detected light reflected by or transmitted through the optical fiber bend sensor; and a control system comprising a servo controller for effectuating movement of the arm. | 09-15-2011 |
20110224689 | ROBOTIC SURGERY SYSTEM INCLUDING POSITION SENSORS USING FIBER BRAGG GRATINGS - A surgical instrument is provided, including: at least one articulatable arm having a distal end, a proximal end, and at least one joint region disposed between the distal and proximal ends; an optical fiber bend sensor provided in the at least one joint region of the at least one articulatable arm; a detection system coupled to the optical fiber bend sensor, said detection system comprising a light source and a light detector for detecting light reflected by or transmitted through the optical fiber bend sensor to determine a position of at least one joint region of the at least one articulatable arm based on the detected light reflected by or transmitted through the optical fiber bend sensor; and a control system comprising a servo controller for effectuating movement of the arm. | 09-15-2011 |
20110224825 | ROBOTIC SURGERY SYSTEM INCLUDING POSITION SENSORS USING FIBER BRAGG GRATINGS - A surgical instrument is provided, including: at least one articulatable arm having a distal end, a proximal end, and at least one joint region disposed between the distal and proximal ends; an optical fiber bend sensor provided in the at least one joint region of the at least one articulatable arm; a detection system coupled to the optical fiber bend sensor, said detection system comprising a light source and a light detector for detecting light reflected by or transmitted through the optical fiber bend sensor to determine a position of at least one joint region of the at least one articulatable arm based on the detected light reflected by or transmitted through the optical fiber bend sensor; and a control system comprising a servo controller for effectuating movement of the arm. | 09-15-2011 |
20120046669 | RETROGRADE INSTRUMENT - A minimally invasive surgical instrument includes a U-turn mechanism that transmits actuating forces around a U-turn. The U-turn mechanism is coupled between segments of the instrument and has a bend radius that is smaller than flexible arms having a similar cross section diameter. The actuating forces transmitted by the U-turn mechanism are used to move distal components of the instrument, such as an end effector and a wrist mechanism. | 02-23-2012 |
20140018613 | HERMETICALLY SEALED ENDOSCOPE - In one embodiment, an endoscopic camera for a robotic surgical system includes a stereo camera module mounted to a robotic arm of a patient side cart. The optical and electro-optic components of the camera module are hermetically sealed within a first housing. Signals from an electro-optic component travel through traces in a ceramic substrate forming one side of the hermetically sealed first housing. A second housing surrounds the first housing and optical fibers are dispersed between the housings to provide lighting in a body cavity. The camera module may be sterilized by an autoclave. | 01-16-2014 |
20150190037 | STEREO CAMERA FOR HERMETICALLY SEALED ENDOSCOPE - In one embodiment, an endoscopic camera for a robotic surgical system includes a stereo camera module mounted to a robotic arm of a patient side cart. The optical and electro-optic components of the camera module are hermetically sealed within a first housing. Signals from an electro-optic component travel through traces in a ceramic substrate forming one side of the hermetically sealed first housing. A second housing surrounds the first housing and optical fibers are dispersed between the housings to provide lighting in a body cavity. The camera module may be sterilized by an autoclave. | 07-09-2015 |
Patent application number | Description | Published |
20090313286 | GENERATING TRAINING DATA FROM CLICK LOGS - Data from a click log may be used to generate training data for a search engine. The pages clicked as well as the pages skipped by a user may be used to assess the relevance of a page to a query. Labels for training data may be generated based on data from the click log. The labels may pertain to the relevance of a page to a query. | 12-17-2009 |
20100114925 | CUSTOMIZED SEARCH - Techniques are disclosed herein for providing a custom search engine. In one aspect, a first search query is received from a requestor. First search results contain search result items that match the first search query are obtained. A least one sub-query is generated from the first search results. The generating is based on rules for a particular custom search engine. Second search results that match the sub-query are then obtained. A search result set is formed from a corpus that includes the first search results and the second search results. The generating of the search result set is based on the rules for the particular custom search engine. The search result set is provided to the requester. In one aspect an interface for designing a custom search engine is provided. The interface allows the designer to specify the layout of a search results page. | 05-06-2010 |
20100318539 | LABELING DATA SAMPLES USING OBJECTIVE QUESTIONS - Described is a technology for obtaining labeled sample data. Labeling guidelines are converted into binary yes/no questions regarding data samples. The questions and data samples are provided to judges who then answer the questions for each sample. The answers are input to a label assignment algorithm that associates a label with each sample based upon the answers. If the guidelines are modified and previous answers to the binary questions are maintained, at least some of the previous answers may be used in re-labeling the samples in view of the modification. | 12-16-2010 |
20110047171 | ANSWERING WEB QUERIES USING STRUCTURED DATA SOURCES - Described is answering online web queries from a structured data store, such as a products database. An online web search query is modified into an evaluation expression for accessing a structured data store (e.g., a database, XML file, a flat table) to find search results. A query is matched to a pattern, which is used to generate the expression, as well as determine to which structured data store the query is routed. Tokens (e.g., words) in the query are processed against a dictionary of token classes (sets of tokens) and patterns (sets of token classes) to annotate the query to map the query to the matching pattern. A translation process generates the expression based on translation hints that correspond to the matching pattern. Also described is offline mining of query logs to generate the dictionaries. | 02-24-2011 |
20120276992 | MOST VALUABLE PLAYER GAMER STATUS AND APPLICATIONS - A gaming environment is provided by an MVP gaming system provider in which “most valuable player” (MVP) gamers may compete. MVP gamers may be identified using achievements, gamer scores, game play during sanctioned gaming events, or other indicia of game skills. The MVP gamers may be sponsored by advertisers, and the MVP gamers' avatars may be branded based on sponsorship during gaming events. The sponsorships may be brokered by the MVP gaming system provider. Some gaming events may be sanctioned gaming events that are coordinated by the MVP gaming system provider and “televised” to allow viewers to watch the gaming events. Tutorials from MVP gamers may also be provided to gamers for viewing to assist in their game play. Further, gamers may be able to rent the avatars of MVP gamers for use during their game play. | 11-01-2012 |
20120277004 | BRINGING ACHIEVEMENTS TO AN OFFLINE WORLD - An achievement system tracks users' offline activities and awards achievements to users for participation in particular offline activities. The achievements that are awarded for particular activities and/or to particular users may be sponsored by merchants, who may compensate an achievement system provider for the opportunity to sponsor the achievements. To award users achievements, the users' offline activities are tracked. When a user participates in an offline activity for which achievements are available, the user is awarded an achievement. The achievement may be stored in an achievement profile for the user. In some embodiments, achievements earned by users may be converted into other benefits and alternative awards. | 11-01-2012 |
20120278154 | MARKETING INVENTORY BASED ON SPOILAGE - An inventory marketing system operates to identify and market inventory items that are likely to spoil. Initially, inventory items that have a particular likelihood of spoilage may be identified. Customers to target with offers for the inventory items may be identified based on the customers' current location or expected location near a spoilage time for the inventory items. Offers for the inventory items may be provided to the targeted customers, and purchases of the inventory items by customers may be facilitated. | 11-01-2012 |
20130275441 | COMPOSING TEXT AND STRUCTURED DATABASES - A framework is provided for composing texts about objects with structured information about these objects, and thus disclosed are methodologies for linking information from at least two data sources—one comprising a plurality of documents comprising text pertaining to at least one object, and one comprising a plurality of structured records comprising at least one characteristic of the at least one object, each characteristic comprising one property name and an associated property value corresponding to the property name for the at least one object—by determining one or more instance-based traits for each object in both data sources and associating at least one record with at least one document that refers to each object, each trait comprising one or more characteristics that identifiably distinguish each object from all other objects. | 10-17-2013 |
20140101267 | SELECTING USER ACCOUNTS IN SOCIAL NETWORK TO ANSWER QUESTION - Messages generated by user accounts in a social networking application over a period of time are processed to determine the subjects and topic associated with the messages, as well as the geographical locations of the users associated with the user accounts, and the times when the users associated with the accounts are most active. The determined, subject, time, and location information is used to create a model that may be used to predict whether a user in the social networking application is willing, available, and has the knowledge or topical affinity to answer a question proposed by another user in the social networking application based on a subject, time, and/or location associated with the question. When a user enters a question, the user may be presented with a list of their friends or contacts ranked according to the probabilities generated by the model. | 04-10-2014 |
Patent application number | Description | Published |
20110112877 | Method and Apparatus for Constraint-based Staff Scheduling - A constraint-based framework models and solves the problem of assigning staff, for example a set of cardiologists, to various work-shifts or work-assignments, for example a day shift and a night shift, for a pre-defined scheduling horizon, for example three months. A work-schedule is produced, which is defined as a list of staff-shift or staff-assignment combinations that meet the various criteria set by the staff and the healthcare facility on how the staff need to work. The staff then uses this work-schedule to perform the needed activities for the amount of time specified by the scheduling horizon. The scheduling problem is modeled with the help of constraints and variables to express the physical constraints specified by the staff on their work schedules and the needs of the healthcare facility. By embedding the scheduling model within a software program, a work-schedule is produced quickly that meets the requirements of the staff and the healthcare facility. | 05-12-2011 |
20120130765 | METHOD AND APPARATUS FOR CONSTRAINT-BASED STAFF SCHEDULING - A constraint-based framework models and solves the problem of assigning staff to various work-shifts or work-assignments, for example a day shift and a night shift, for a pre-defined scheduling horizon, for example three months. A work-schedule is produced, which is defined as a list of staff-shift or staff-assignment combinations that meet the various criteria set by the staff and the healthcare facility on how the staff need to work. The staff then uses this work-schedule to perform the needed activities for the amount of time specified by the scheduling horizon. The scheduling problem is modeled with the help of constraints and variables to express the physical constraints specified by the staff on their work schedules and the needs of the healthcare facility. By embedding the scheduling model within a software program, a work-schedule is produced quickly that meets the requirements of the staff and the healthcare facility. | 05-24-2012 |