Sonar
Ajay Sonar, Farmington Hills, MI US
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20090189429 | Easy lift mechanism for vehicle seats - A method and apparatus for actuating a folding vehicle seat. The apparatus includes a handle remotely and functionally connected to the vehicle seat for moving the seatback from a folded position to an upright or design position. The handle is pivotally mounted on a support bracket and attached to an actuator member interconnecting the handle and the seatback. The actuator member transfers the motion of the handle to a generally “L-shaped” arm which is pivotally mounted to the vehicle seat below the seatback. The L-shaped arm rotates toward the back of the seat as the handle is lifted. As the L-shaped arm moves, it catches a stop or extension member located on the seatback and moves the seatback toward the upright position. | 07-30-2009 |
Prashant Sonar, Singapore SG
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20120153274 | AMBIPOLAR POLYMERIC SEMICONDUCTOR MATERIALS AND ORGANIC ELECTRONIC DEVICES - There is provided compounds of formula I, ambipolar semiconductor material derived from such compounds and devices comprising such ambipolar semiconductor material. | 06-21-2012 |
20120161117 | P-TYPE MATERIALS AND ORGANIC ELECTRONIC DEVICES - There is presently provided compounds of formula (I), which are useful as p-type semiconductor materials and in devices comprising such p-type semiconductor materials. | 06-28-2012 |
20120298976 | N-Type Materials And Organic Electronic Devices - There is presently provided organic compounds of formula I, n-type acceptor materials derived from such compounds and devices comprising such n-type acceptor materials. | 11-29-2012 |
Sandip Satish Sonar, Pune IN
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20140231144 | Downhole Rotational Lock Mechanism - The subject matter of this specification can be embodied in, among other things, a method that includes a downhole rotational lock mechanism including a tubular housing having a longitudinal bore with an internal wall. A driving gear is disposed in the longitudinal bore of the tubular housing and has a peripheral edge secured to the internal wall of the longitudinal bore of the tubular housing. The driving gear has an upper portion including a plurality of gear teeth arranged around a central longitudinal bore through the driving gear. A driven gear is movably disposed in the longitudinal bore of the tubular housing, and has a central longitudinal bore and a lower portion including a plurality of gear teeth. An output drive shaft is disposed longitudinally in the longitudinal bore of the tubular housing and in the longitudinal bore of the driven gear. | 08-21-2014 |
20150083541 | ANTI-STALL MECHANISM - The subject matter of this specification can be embodied in, among other things, a locking clutch that includes a collection of movable locking blocks slidably coupled to the rotatable output shaft. The movable locking blocks slide radially inwardly and outwardly with respect to a central longitudinal axis of the rotatable output shaft, and are spaced apart circumferentially about the rotatable output shaft, with each movable locking block having a first contacting face and a second contacting face. A collection of fixed locking blocks are coupled to the rotatable housing, and are positioned radially around the output shaft and spaced apart circumferentially about the interior of the rotatable housing a distance sufficient to receive one of the movable locking blocks when it moves inwardly toward the central axis of the rotatable output shaft, each said fixed locking block having a first contacting face and a second contacting face. | 03-26-2015 |
Sandip Satish Sonar, Leduc CA
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20160130895 | ROTATIONAL ANCHORING OF DRILL TOOL COMPONENTS - A rotational anchor mechanism is mounted on an operatively nonrotating housing that forms part of a drill string. An anchor linkage forming part of the anchor mechanism is radially extendable and contractible to move an anchor member, such as a roller, mounted on the anchor linkage radially towards and away from the housing, to engage a borehole wall for resisting rotation of the housing relative to drill pipe that is drivingly rotated within the housing. The anchor linkage includes operatively coupled mounting links mounted on the housing to pivot about respective mounting axes which are parallel to one another in a fixed spatial relationship. An actuating mechanism is coupled to the anchor linkage to exert an actuating force on the anchor linkage. An angular orientation of the actuating force relative to the housing varies in response to variation in radial expansion of the anchor linkage. | 05-12-2016 |
Sanjay Sonar, Thane IN
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20150376228 | PROCESS FOR HIGH EFFICIENCY REFOLDING OF RECOMBINANT PROTEINS - A process of refolding a recombinant protein from inclusion bodies (IBs) formed inside a host cell, is provided. The process includes homogenising a wet cells slurry to obtain a cell lysate; incubating the cell lysate with a reducing agent to obtain a reduced cell lysate; isolating reduced IBs from the reduced cell lysate to obtain isolated IBs; solubilising the isolated IBs with a denaturing agent to obtain solubilised IBs; and subjecting the solubilised IBs to a unit process of refolding to obtain a refolded recombinant protein. | 12-31-2015 |
20160039868 | PROCESS FOR ISOLATION AND STABILISATION OF KEY INTERMEDIATES FOR HIGH EFFICIENCY REFOLDING OF RECOMBINANT PROTEINS - A process for obtaining a refolded recombinant protein from an unfolded recombinant protein present in inclusion bodies isolated from wet cells harvested from a cell culture is provided. The process includes a) reducing the inclusion bodies by treating the inclusion bodies with a reducing buffer, to obtain reduced inclusion bodies; b) obtaining stable first intermediate state I | 02-11-2016 |
Sanjay M. Sonar, Mumbai IN
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20140121363 | Bioreactive Agents - This invention relates to agents and conjugates that can be used to detect and isolate target components from complex mixtures such as nucleic acids from biological samples, cells from bodily fluids, and nascent proteins from translation reactions. The invention also relates to targets isolated with conjugates which may be useful as pharmaceutical agents or compositions that can be administered to humans and other mammals. The invention further relates to kits comprised of agents and conjugates that can be used for the detection of diseases, disorders and individual substances in a complex background of substances. | 05-01-2014 |
Sanjay M. Sonar, Thane IN
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20090075253 | BIOREACTIVE AGENTS - This invention relates to agents and conjugates that can be used to detect and isolate target components from complex mixtures such as nucleic acids from biological samples, cells from bodily fluids, and nascent proteins from translation reactions. Agents comprise a detectable moiety bound to a photoreactive moiety. Conjugates comprise agents coupled to substrates by covalent bounds which can be selectively cleaved with the administration of electromagnetic radiation. Targets substances labeled with detectable molecules can be easily identified and separated from a heterologous mixture of substances. Exposure of the conjugate to radiation releases the target in a functional form and completely unaltered. Using photocleavable molecular precursors as the conjugates, label can be incorporated into macromolecules, the nascent macromolecules isolated and the label completely removed. The invention also relates to targets isolated with these conjugates which may be useful as pharmaceutical agents or compositions that can be administered to humans and other mammals. Useful compositions include biological agents such as nucleic acids, proteins, lipids and cytokines. Conjugates can also be used to monitor the pathway and half-life of pharmaceutical composition in vivo and for diagnostic, therapeutic and prophylactic purposes. The invention also relates to kits comprised of agents and conjugates that can be used for the detection of diseases, disorders and nearly any individual substance in a complex background of substances. | 03-19-2009 |
20090176279 | Bioreactive agents - This invention relates to agents and conjugates that can be used to detect and isolate target components from complex mixtures such as nucleic acids from biological samples, cells from bodily fluids, and nascent proteins from translation reactions. Agents comprise a detectable moiety bound to a photoreactive moiety. Conjugates comprise agents coupled to substrates by covalent bounds which can be selectively cleaved with the administration of electromagnetic radiation. Targets substances labeled with detectable molecules can be easily identified and separated from a heterologous mixture of substances. Exposure of the conjugate to radiation releases the target in a functional form and completely unaltered. Using photocleavable molecular precursors as the conjugates, label can be incorporated into macromolecules, the nascent macromolecules isolated and the label completely removed. The invention also relates to targets isolated with these conjugates which may be useful as pharmaceutical agents or compositions that can be administered to humans and other mammals. Useful compositions include biological agents such as nucleic acids, proteins, lipids and cytokines. Conjugates can also be used to monitor the pathway and half-life of pharmaceutical composition in vivo and for diagnostic, therapeutic and prophylactic purposes. The invention also relates to kits comprised of agents and conjugates that can be used for the detection of diseases, disorders and nearly any individual substance in a complex background of substances. | 07-09-2009 |
Sanjay M. Sonar, Boston, MA US
Patent application number | Description | Published |
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20120190035 | Detection Of Disease Related Genes - The invention is directed to methods for the non-radioactive labeling, detection, quantitation and isolation of nascent proteins translated in a cellular or cell-free translation system. tRNA molecules are misaminoacylated with non-radioactive markers which may be non-native amino acids, amino acid analogs or derivatives, or substances recognized by the protein synthesizing machinery. Markers may comprise cleavable moieties, detectable labels, reporter properties wherein markers incorporated into protein can be distinguished from unincorporated markers, or coupling agents which facilitate the detection and isolation of nascent protein from other components of the translation system. The invention also comprises proteins prepared using misaminoacylated tRNAs which can be utilized in pharmaceutical compositions for the treatment of diseases and disorders in humans and other maninials, and kits which may be used for the detection of diseases and disorders. | 07-26-2012 |
Sanjay M. Sonar, Thane (w) IN
Patent application number | Description | Published |
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20100196988 | Bioreactive Agents - This invention relates to agents and conjugates that can be used to detect and isolate target components from complex mixtures such as nucleic acids from biological samples, cells from bodily fluids, and nascent proteins from translation reactions. Agents comprise a detectable moiety bound to a photoreactive moiety. Conjugates comprise agents coupled to substrates by covalent bounds which can be selectively cleaved with the administration of electromagnetic radiation. Targets substances labeled with detectable molecules can be easily identified and separated from a heterologous mixture of substances. Exposure of the conjugate to radiation releases the target in a functional form and completely unaltered. Using photocleavable molecular precursors as the conjugates; label can be incorporated into macromolecules, the nascent macromolecules isolated and the label completely removed. The invention also relates to targets isolated with these conjugates which may be useful as pharmaceutical agents or compositions that can be administered to humans and other mammals. Useful compositions include biological agents such as nucleic acids, proteins, lipids and cytokines. Conjugates can also be used to monitor the pathway and half-life of pharmaceutical composition in vivo and for diagnostic, therapeutic and prophylactic purposes. The invention also relates to kits comprised of agents and conjugates that can be used for the detection of diseases, disorders and nearly any individual substance in a complex background of substances. | 08-05-2010 |
20110129878 | BIOREACTIVE AGENTS - This invention relates to agents and conjugates that can be used to detect and isolate target components from complex mixtures such as nucleic acids from biological samples, cells from bodily fluids, and nascent proteins from translation reactions. Agents comprise a detectable moiety bound to a photoreactive moiety. Conjugates comprise agents coupled to substrates by covalent bounds which can be selectively cleaved with the administration of electromagnetic radiation. Targets substances labeled with detectable molecules can be easily identified and separated from a heterologous mixture of substances. Exposure of the conjugate to radiation releases the target in a functional form and completely unaltered. Using photocleavable molecular precursors as the conjugates, label can be incorporated into macromolecules, the nascent macromolecules isolated and the label completely removed. The invention also relates to targets isolated with these conjugates which may be useful as pharmaceutical agents or compositions that can be administered to humans and other mammals. Useful compositions include biological agents such as nucleic acids, proteins, lipids and cytokines. Conjugates can also be used to monitor the pathway and half-life of pharmaceutical composition in vivo and for diagnostic, therapeutic and prophylactic purposes. The invention also relates to kits comprised of agents and conjugates that can be used for the detection of diseases, disorders and nearly any individual substance in a complex background of substances. | 06-02-2011 |
20120088241 | Bioreactive Agents - This invention relates to agents and conjugates to detect and isolate target components from complex mixtures such as nucleic acids from biological samples, cells from bodily fluids, and nascent proteins from translation reactions. Agents comprise a detectable moiety bound to a photoreactive moiety. Conjugates comprise agents coupled to substrates by covalent bounds which can be selectively cleaved with the administration of electromagnetic radiation. Targets substances labeled with detectable molecules can be easily identified and separated from a heterologous mixture of substances. Exposure of the conjugate to radiation releases the target in a functional form and completely unaltered. Using photocleavable molecular precursors as the conjugates, label can be incorporated into macromolecules, the nascent macromolecules isolated and the label completely removed. The invention also relates to targets isolated with these conjugates which may be useful as pharmaceutical agents or compositions that can be administered to humans and other mammals. | 04-12-2012 |
Sanjay Madhukar Sonar, Thane IN
Patent application number | Description | Published |
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20150105537 | CODON OPTIMIZED SEQUENCE FOR AN ANTIVIRAL PROTEIN - A codon optimized nucleic acid sequence for Interferon Alpha-2a is provided which can be used for expression of Interferon Alpha-2a in | 04-16-2015 |
20150118754 | STABLE EXPRESSION SYSTEM FOR EUKARYOTIC CELLS - The present invention related to a polynucleotide sequence and an expression vector comprising at least one gene encoding a stress resistance protein, at least one gene encoding a selection marker, at least one gene encoding an expression protein, at least one matrix attachment region and a transcription terminator, all of which are operably connected to each other. The present invention further relates to a host cell comprising the expression vector. The present invention also relates a method of producing a cell line. | 04-30-2015 |
20160060291 | PROCESS FOR RENATURATION OF POLYPEPTIDES - The invention relates to method of refolding of proteins from a solution containing the protein in predominantly misfolded, aggregated form. The method involves denaturation and reduction of the protein of interest. The denatured and reduced preparation is subjected to removal of reducing agent in denaturing condition and at low pH to prevent the misfolding of the protein. The protein preparation is subjected to refolding followed by removal of the refolding buffer components. | 03-03-2016 |
Vijayakumar Sonar, Little Rock, AR US
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20160068506 | COMBRETASTATIN ANALOGS - The present invention relates novel heterocyclic analogs of combretastatin, their synthesis, and their use as anti-cancer compounds. In particular, compounds of Formula (I), Formula (II), and Formula (V) are provided. | 03-10-2016 |