Brass, US
Abraham Brass, Newton, MA US
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20120331576 | Pathogen Restriction Factors - The use of interferon induced transmembrane protein 1, 2, or 3 (IFITM1, 2, or 3) as a viral restriction factor, and methods of using the same to produce virus, transgenic animals expressing exogenous IFITM1, 2, or 3, and methods of treating or inhibiting viral infections by targeting a gene identified herein | 12-27-2012 |
Abraham L. Brass, Newton, MA US
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20100273859 | TREATMENT AND PREVENTION OF HIV INFECTION - Disclosed herein are methods for treating and/or preventing HIV infection in a cell. The methods involve downmodulating one or more of the HIV-dependency factors (HDFs) disclosed herein to thereby treat and/or prevent HIV infection in the cell. Downmodulating the HDFs can be by contacting the cell with an agent that downmodulates the HDF. Also disclosed herein are methods for treating and/or preventing HIV infection in a subject comprising downmodulating one or more of the HIV-dependency factors (HDFs), disclosed herein, to thereby treat and/or prevent HIV infection in the subject. The method may further comprise selecting a subject diagnosed with or at risk for HIV infection, prior to downmodulating. Downmodulating the HDFs may comprise administering an agent that downmodulates the HDF to the subject such that the agent contacts HIV host cells of the subject. The agent may inhibit HDF gene expression, protein synthesis, HDF function or HDF activity, or combinations thereof. | 10-28-2010 |
Brad P. Brass, Palos Verdes, CA US
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20140065695 | PEPTIDES AND METHODS FOR INDUCING CELL DEATH - The invention provide isolated peptides, protides and conjugates having novel peptide sequences which are able to induce antimicrobial, anti-cancer, anti-inflammatory, anti-proliferative or programmed cell death activity. The invention also provides a method of inducing programmed cell death in a cell by contacting the cell with an isolated peptide, protide or conjugate described herein. In some aspects, the method can be used in the diagnosis, prevention, or treatment of a disease, such as an infection, cancer, autoimmune disease, or inflammatory disease. | 03-06-2014 |
Clifford A. Brass, New York, NY US
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20100226885 | METHOD OF TREATING HEPATITIS C PATIENTS - This application discloses a novel method of identifying patients amongst treatment naïve patients suffering from HCV infection that are amenable to treatment with a protease inhibitor. The application also discloses a method of treating treatment naïve, nonresponder and relapsed patients suffering from an HCV infection. | 09-09-2010 |
20120282224 | MARKERS ASSOCIATED WITH RIBAVIRIN-INDUCED ANEMIA - The present invention provides genetic markers and biomarkers that are associated with anemia induced by ribavirin therapy. The genetic markers are located in the ITPA gene and elsewhere on human chromosome 20 and the biomarkers are low ITPA activity phenotypes. These markers of ribavirin-induced anemia are useful, inter alia, to identify patients who are least likely to develop anemia upon treatment with ribavirin pharmaceutical compositions and drug products, in methods of treating patients having a disease susceptible to treatment with ribavirin, and in methods for selecting the most appropriate therapy for such patients. | 11-08-2012 |
Daniel W. Brass, Berea, OH US
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20120186688 | SAFETY WIRE PLIER - A safety wire plier includes a pair of plier arms with each of the arms including a jaw end and a handle. The plier arms of the safety wire plier are pivotally connected to each other for movement in either an open or closed position. The safety wire plier also includes a sealed lock for releasably locking the safety wire plier in the closed position. | 07-26-2012 |
Eric P. Brass, Palos Verdes, CA US
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20110288006 | Peptides and methods for inducing cell death - The invention provide isolated peptides, protides and conjugates having novel peptide sequences which are able to induce antimicrobial, anti-cancer, anti-inflammatory, anti-proliferative or programmed cell death activity. The invention also provides a method of inducing programmed cell death in a cell by contacting the cell with an isolated peptide, protide or conjugate described herein. In some aspects, the method can be used in the diagnosis, prevention, or treatment of a disease, such as an infection, cancer, autoimmune disease, or inflammatory disease. | 11-24-2011 |
20150232521 | PEPTIDES AND METHODS FOR INDUCING CELL DEATH - The invention provide isolated peptides, protides and conjugates having novel peptide sequences which are able to induce antimicrobial, anti-cancer, anti-inflammatory, anti-proliferative or programmed cell death activity. The invention also provides a method of inducing programmed cell death in a cell by contacting the cell with an isolated peptide, protide or conjugate described herein. In some aspects, the method can be used in the diagnosis, prevention, or treatment of a disease, such as an infection, cancer, autoimmune disease, or inflammatory disease. | 08-20-2015 |
Laura Brass, Newton, MA US
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20120095217 | FLUORINE CONTAINING COMPOUNDS AND METHODS OF USE THEREOF - Fluorinated compounds and methods of making fluorinated compounds are described herein. | 04-19-2012 |
20120149900 | FLUORINE CONTAINING COMPOUNDS AND METHODS OF USE THEREOF - Fluorinated compounds and methods of making fluorinated compounds are described herein. | 06-14-2012 |
Lawrence F. Brass, Bala Cynwyd, PA US
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20100040617 | Method of Using CD100 (or Sema4D) to Mediate Platelet Activation and Inflammatory Responses - This invention relates to methods of treating platelet disorders and/or endothelial cell disorders by modulating sema4D/CD100 activity. Specifically, this invention involves the use of compounds to increase or decrease the level of soluble sema4D/CD100. | 02-18-2010 |
Philip Charles Brass, Roswell, GA US
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20100083382 | Method and System for Managing Computer Security Information - A security management system includes a fusion engine which “fuses” or assembles information from multiple data sources and analyzes this information in order to detect relationships between raw events that may indicate malicious behavior and to provide an organized presentation of information to consoles without slowing down the processing performed by the data sources. The multiple data sources can comprise sensors or detectors that monitor network traffic or individual computers or both. The sensors can comprise devices that may be used in intrusion detection systems (IDS). The data sources can also comprise firewalls, audit systems, and other like security or IDS devices that monitor data traffic in real-time. The present invention can identify relationships between one or more real-time, raw computer events as they are received in real-time. The fusion engine can also assess and rank the risk of real-time raw events as well as mature correlation events. | 04-01-2010 |
Richard Brass, Friday Harbor, WA US
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20110104963 | ELECTRICALLY POWERED WATERCRAFT - Improvements to electrically powered watercraft including kayaks are disclosed. The watercraft comprises a hull defining a cavity and a battery powered retractable propulsion unit. The retractable propulsion unit can be retracted into the cavity with powered or unpowered means. Various retractable propulsion units are disclosed, including propulsion units that are steerable wherein the thrust can be selectively directed. Specific embodiments to improve the steerability of electrically powered watercraft are disclosed. Mechanisms for disengaging the steering controls from the retractable propulsion units are also disclosed. Locking mechanisms for locking the retractable propulsion unit in an extended or fully retracted position are also disclosed. | 05-05-2011 |
20140336927 | WATERCRAFT AUTO-PILOT - Improvements to auto pilots and other control systems for watercraft are disclosed. The disclosed autopilot features may be used for example in conjunction with an improved electrically powered watercraft detailed herein, or with other types of watercraft. The improved electrically powered watercraft evidences significant advancements in steerability, portability, efficiency and other tangible aspects. | 11-13-2014 |
Richard I. Brass, Friday Harbor, WA US
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20080299842 | ELECTRICALLY POWERED WATERCRAFT - Improvements to electrically powered watercraft including kayaks are disclosed. The watercraft comprises a hull defining a cavity and a battery powered retractable propulsion unit. The retractable propulsion unit can be retracted into the cavity with powered or unpowered means. Various retractable propulsion units are disclosed, including propulsion units that are steerable wherein the thrust can be selectively directed. Specific embodiments to improve the steerability of electrically powered watercraft are disclosed. Mechanisms for disengaging the steering controls from the retractable propulsion units are also disclosed. Locking mechanisms for locking the retractable propulsion unit in an extended or fully retracted position are also disclosed. | 12-04-2008 |
Stephen Brass, South Dartmouth, MA US
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20080255708 | SMART WATER TIMER - A smart water timer which includes a water timer, a receiving unit connected to the water timer, and a moisture sensing unit which is in wireless communication with the receiving unit. The smart water timer can sense when the moisture level in the soil is too moist (based on a user setting) and turn off a water supply to a sprinkler as a result A soil moisture sensing unit is placed in the soil in the area to be watered. The soil moisture sensing unit uses a moisture sensing probe and wirelessly transmits a data signal to the receiver, which is connected to the water timer, indicating whether or not the water timer should be permitted to open a water valve. | 10-16-2008 |
Stephen Campbell Brass, Washington, DC US
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20150268670 | WIRELESS APPARATUS, SYSTEM, AND METHOD FOR CONTROLLING A VALVE - A wireless water timer and valve control system includes a control unit in wireless WiFi communication with a router and a valve unit in wireless communication with the control unit and designed to connect to a faucet. The valve unit includes a valve that is operated wirelessly via a signal received by the control unit. | 09-24-2015 |
William J. Brass, Largo, FL US
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20100194505 | MAGNETIC CLIPS AND SUBSTRATE HOLDERS FOR USE IN A PLASMA PROCESSING SYSTEM - Magnetic clips for use with a substrate holder for holding a substrate in a processing chamber of a plasma treatment system. The clip includes first and second body members each having a clamping surface and a magnet. The first body member is configured to be mechanically connected with the substrate holder. The second body member is pivotally connected by a hinge with the first body member for movement relative to the first body member between closed and opened positions. In the closed position, an edge region of the substrate is positioned between the clamping surfaces. In the opened position, the edge region is released. The magnet on the second body member magnetically attracts the magnet on the first body member, when the second body member is in the closed position, to apply a force that restrains movement of the edge region of the substrate relative to the clamping surfaces. | 08-05-2010 |