Mead
Alice Mead, Cambridge GB
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20150359755 | USE OF CANNABINOIDS IN THE TREATMENT OF EPILEPSY - The present disclosure relates to the use of cannabidiol (CBD) for the reduction of total convulsive seizure frequency in the treatment of “treatment-resistant epilepsy” (TRE). In particular, the disclosure relates to the use of CBD of treating TRE when the TRE is Dravet syndrome; myoclonic absence seizures or febrile infection related epilepsy syndrome (FIRES). The disclosure further relates to the use of CBD in combination with one or more anti-epileptic drugs (AEDs). | 12-17-2015 |
20150359756 | USE OF CANNABINOIDS IN THE TREATMENT OF EPILEPSY - The present disclosure relates to the use of cannabidiol (CBD) in the treatment of absence seizures. In particular, the disclosure relates to the use of CBD for reducing absence seizures in patients suffering with etiologies that include: Lennox-Gastaut Syndrome; Tuberous Sclerosis Complex; Dravet Syndrome; Doose Syndrome; CDKL5; Dup15q; Jeavons syndrome; Myoclonic Absence Epilepsy; Neuronal ceroid lipofuscinoses (NCL) and brain abnormalities. The disclosure further relates to the use of CBD in combination with one or more anti-epileptic drugs (AEDs). | 12-17-2015 |
Barry Mead, Grays GB
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20120103719 | EXHAUST FILTER - An exhaust muffler comprising an inlet in fluid communication with an outlet via an expansion chamber ( | 05-03-2012 |
Bruce Mead, Mississauga CA
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20080263975 | Printed border - A floor panel for an elevated floor including a printed border along the edge of the floor panel and a protective wear surface over the printed surface. | 10-30-2008 |
20090113844 | Access floor grounding fastener - A fastener for Connecting a panel to a support, comprising at least one projection for penetrating said panel surface upon fastenings of panel to said support and make electrical contact thereto | 05-07-2009 |
Christl Lisa Mead, St. Martin I.s. AT
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20120181474 | CERAMIC MATERIAL AND PROCESS FOR PRODUCING THE CERAMIC MATERIAL - A material includes a ceramic material having a general formula of | 07-19-2012 |
Curtis C. Mead, San Jose, CA US
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20160064130 | Electronic Device With Signal Line Routing To Minimize Vibrations - An electronic device may have a source of magnetic field such as a magnet that produces a static magnetic field. A flexible printed circuit may have a flexible tail that surrounds a central portion. The central portion may overlap the magnet. Electrical components may be mounted to the central portion. To prevent undesired vibrations and noise due to interactions between magnetic fields induced by signals flowing in signal lines in the flexible printed circuit and the static magnetic field, the signal lines may be vertically stacked or may be routed along a curved path that does not overlap the magnet. The tail may serve as a service loop that allows a portion of a housing for the device and electrical components mounted to the central portion in alignment with windows in the housing to be detached for servicing. | 03-03-2016 |
David Mead, Middleton, WI US
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20150198533 | LUCIGEN YELLOW (LucY), A YELLOW FLUORESCENT PROTEIN - Described herein are isolated polynucleotides that encode a fluorescent protein which is at least 80% sequence identical to a protein selected from the group consisting of SEQ. ID. NOS: 2, 4, 6, 10, 14, 18, 22, 26, 30, 34, 38, 42, 46, 50, 54, 58, 62, 66, 70, and 74. Also described are expression constructs containing the polynucleotides, transformed host cells containing the expression constructions, the encoded fluorescent proteins themselves, and methods of using the nucleotides and encoded fluorescent proteins for bioanalytical research. | 07-16-2015 |
David John Mead, Nottingham GB
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20110301329 | Process for the Purification of Recombinant Albumin - A process is provided for the preparation of a highly pure albumin solution the process comprising subjecting albumin (preferably expressed and secreted by transformed yeast) to a series of chromatographic steps. Preferably, the process comprises the steps of positive mode cation exchange chromatography, positive mode anion exchange chromatography, positive mode affinity chromatography, negative mode affinity chromatography (preferably using immobilised aminophenylboronic acid), negative mode cation exchange chromatography, and negative or positive mode anion exchange chromatography. A process for reducing the level of nickel in an albumin solution is also disclosed, as is a recombinant albumin coding sequence comprising two or more in-frame translation stop codons. Also disclosed is a process for producing recombinant albumin, the process comprising culturing a fungal cell expressing a is recombinant albumin coding sequence, wherein the cell has a reduced capacity of mannosylation of the recombinantly-expressed albumin. | 12-08-2011 |
20150056654 | PROCESS FOR THE PURIFICATION OF RECOMBINANT ALBUMIN - A process is provided for the preparation of a highly pure albumin solution the process comprising subjecting albumin (preferably expressed and secreted by transformed yeast) to a series of chromatographic steps. Preferably, the process comprises the steps of positive mode cation exchange chromatography, positive mode anion exchange chromatography, positive mode affinity chromatography, negative mode affinity chromatography (preferably using immobilised aminophenylboronic acid), negative mode cation exchange chromatography, and negative or positive mode anion exchange chromatography. A process for reducing the level of nickel in an albumin solution is also disclosed, as is a recombinant albumin coding sequence comprising two or more in-frame translation stop codons. Also disclosed is a process for producing recombinant albumin, the process comprising culturing a fungal cell expressing a recombinant albumin coding sequence, wherein the cell has a reduced capacity of mannosylation of the recombinantly-expressed albumin. | 02-26-2015 |
David John Mead, Radcliffe On Trent GB
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20090171070 | Process for the Purification of Recombinant Albumin - A process is provided for the preparation of a highly pure recombinant albumin solution having a nickel ion content of less than 100 ng per gram of albumin. The process comprises subjecting a recombinant albumin to a series of chromatography, concentration, and diafiltration steps. | 07-02-2009 |
Edgar Stuart Mead, Great Missenden GB
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20120221122 | METHOD OF CONTROLLING A PROSTHESIS - The present invention relates to a method of controlling a movable component of a prosthesis or orthosis. The method ( | 08-30-2012 |
Elizabeth Mead, Hertfordshire GB
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20140294796 | AROMATIC-CATIONIC PEPTIDES AND USES OF SAME - The disclosure provides compositions and methods relating to aromatic-cationic peptides. The methods comprise administering to the subject an effective amount of an aromatic-cationic peptide to subjects in need thereof. For example, the peptides may be administered to subjects in need of a mitochondrial-targeted antioxidant. | 10-02-2014 |
Graham Mead, Aylesbury GB
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20100230217 | LINEAR MOTOR BRAKE - A mechanical brake for arresting movement of the armature of a linear electric motor in the absence of electrical power comprising a pivotably mounted plate ( | 09-16-2010 |
Graham Mead, Buckinghamshire GB
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20090206683 | Linear Electric Motors - A linear electric motor comprises an electromagnetic piston and cylinder device comprising a plurality of stator coils disposed side by side around an axis and wound so as to create a radial magnetic field which alternates its polarity along the length of the axis, when energised, an armature located within the stator and moveable in a direction co-axial with the axis of the stator, and a bearing arrangement for supporting the armature for reciprocation with respect to the stator, characterised in that the bearing arrangement comprises non-magnetic material. | 08-20-2009 |
Graham Mead, Bucks GB
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20110005328 | BI-AXIAL ELECTROMAGNETIC ACTUATOR - A biaxial electromagnetic actuator for a materials testing apparatus comprises a first electromagnetic actuator for imparting a linear force to an output shaft and a second, direct drive electromagnetic actuator for imparting a rotational force to the shaft. The shaft is mounted in two combination bearings which permit the shaft to move axially and rotationally. One of the bearings is located within a hollow cylindrical member which constitutes the armature of the direct drive actuator in order to provide a compact and symmetrical arrangement. | 01-13-2011 |
Graham Peter Mead, Birmingham GB
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20120220052 | SURVIVAL PROGNOSTIC ASSAY - Assay kit and Assay for determination of likely survival of a subject Assay kits for determining the total amount of free-light chains (FLC) in a sample are provided. Also provided are a general health screen method comprising detecting an amount of free light chains (FLC) in a sample from a subject, wherein a lower amount of FLC is associated with increased survival and/or better general health of the subject, and a higher level of FLC indicates the possible presence of an undetected medical problem. | 08-30-2012 |
20130149792 | CANCER PROGNOSIS ASSAY - The invention provides a method of prognosis of a subject with a cancer, identifying a subject having a greater risk of having an undiagnosed cancer and/or identifying a subject at greater risk of developing a cancer the method comprising detecting an amount of free light chains (FLC) in a sample from a subject, wherein a higher amount of FLC is associated with decreased survival due to a cancer and/or increased risk of the subject having an undiagnosed cancer and/or having an increased risk of developing a cancer. | 06-13-2013 |
20130210168 | ASSAY FOR DETECTING FREE LIGHT CHAINS BY CAPILLARY ZONE ELECTROPHORESIS - The invention provides a method detecting free light chains (FLCs) comprising: (i)providing a sample from a subject; (ii)mixing the sample with an anti-FLC specific antibody, or fragments thereof capable of specifically binding the FLC, to form a mixture; (iii)passing the mixture through a capillary tube by capillary zone electrophoresis (CZE); and (iv)detecting the presence of the antibody or fragment thereof after passage through at least a portion of the capillary tube. Capillary tubes for use in CZE and kits comprising capilliary tubes and at least one anti-FLC antibody are also provided. | 08-15-2013 |
20130217030 | INFECTION PROGNOSTIC ASSAY - The invention provides a method of prognosis of a subject with an infection, identifying a subject at greater risk of death from an infection and/or identifying a subject at greater risk of developing an infection, the method comprising detecting an amount of free light chains (FLC) in a sample from the subject, wherein a higher amount of FLC is associated with decreased survival due to the infection and/or increased risk from an infection and/or having an increased risk of developing an infection. A method of monitoring an infection, comprising detecting an amount of free light chains (FLC) in a sample from a patient having an infection and comparing the amount of FLC in the sample with an amount of FLC detected in a sample previously obtained from the patient, wherein an increase in the amount FLC detected, compared to the previous sample, indicates an increase in the infection in the patient, and a decrease in the amount of FLC indicates a decrease in the infection in the patient. Assay kits for use in the method are also provided. Assay kits comprising one or more anti-FLC antibodies and one or more anti-bacterial antigen antibodies are also provided. | 08-22-2013 |
20130217149 | COMPETITION ASSAY - The application provides competition assays used to detect free-light chains or intact immunoglobulins comprising incubating the sample with anti-FLC antibody, or heavy chain class-light chain type-specific antibodies, or fragments of such antibodies, and a known amount of FLC or intact immunoglobulin and detecting the binding of the antibody to the known amount of FLC or immunoglobulin. Assay kits and methods of producing particles coated with FLC are also provided. | 08-22-2013 |
Howard Brian Mead, Cheshire GB
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20100099592 | PROCESS AND APPARATUS FOR PREPARING A UREA GREASE - The invention provides for a process for preparing a urea grease including: (a) introducing a first feed component to a first feeding zone; (b) introducing a second feed component to a second feeding zone; (c) first reacting-mixing in a first reacting-mixing zone; and (d) cooling-mixing in a cooling-mixing zone. The invention also provides for a process for preparing a urea grease including: (a) introducing a first feed component to a first feeding zone; (b) introducing a second feed component to a second feeding zone; (c) first reacting-mixing in a first reacting-mixing zone; (d) introducing a third feed component to a third feeding zone; (e) second reacting-mixing in a second reacting-mixing zone; and (f) cooling-mixing in a cooling-mixing zone. The invention also provides for an apparatus for preparing a urea grease comprising: (a) a first feeding zone; (b) a second feeding zone; (c) a first reacting-mixing zone; and (d) a cooling-mixing zone. The invention also provides for an apparatus for preparing a urea grease comprising: (a) a first feeding zone; (b) a second feeding zone; (c) a first reacting-mixing zone; (d) a third feeding zone; (e) a second reacting-mixing zone; and (f) a cooling-mixing zone. | 04-22-2010 |
Howard Brian Mead, Chester, Cheshire GB
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20160002557 | PROCESS FOR PREPARING A UREA GREASE - The invention provides for a process for preparing urea grease. The process is carried out in the presence of a base oil and avoids the use of diisocyanate reagents. | 01-07-2016 |
John Mead, Fremont, CA US
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20150271016 | CONFIGURATION OF NETWORKS WITH SERVER CLUSTER DEVICE - Implementations relate to configuration of networks with a server cluster device. In some implementations, a method includes receiving shortest path bridging (SPB) configuration information at one or more of two peer server devices provided in a server cluster having a communication link connecting the peer server devices, where the server cluster is connected to a network and is detectable as a single logical server by a network device on the network. The information is sent from each receiving peer server device to the other peer server device over the communication link, where the information is related to the received SPB configuration information. Network configurations are synchronized on the two peer server devices based on the information sent over the communication link. | 09-24-2015 |
20150271017 | CONFIGURATION OF NETWORKS USING SWITCH DEVICE ACCESS OF REMOTE SERVER - Implementations relate to configuration of networks using switch device access of a remote server. In some implementations, a method includes sending a request from an edge configuration device to an access control server, where the request requests shortest path bridging (SPB) configuration information for a detected end device connected to the edge configuration device, and where the edge configuration device is connected to an SPB network. The method receives at the edge configuration device the SPB configuration information for the end device from the access control server. The edge configuration device is configured to provide the end device access to the SPB network. | 09-24-2015 |
20150271022 | CONFIGURATION OF NETWORKS USING CLIENT DEVICE ACCESS OF REMOTE SERVER - Implementations relate to configuration of networks using client device access of a remote server. In some implementations, a method includes requesting a management server from an end device for shortest path bridging (SPB) configuration information for the end device to communicate on an SPB network, where the end device communicates with the management server over a non-SPB connection. The SPB configuration information is received from the management server, and the SPB configuration information is sent to an edge configuration device connected to the end device, where the SPB configuration information causes configuration of the edge configuration device to allow communication of the end device on the SPB network. | 09-24-2015 |
20150271169 | AUTHENTICATION OF CLIENT DEVICES IN NETWORKS - Implementations relate to authentication of end devices in networks. In some implementations, a method includes receiving identity information at an edge configuration device from an end device via a connection, where the identity information identifies the end device or one or more users associated with the end device. A request is sent from the edge configuration device to an access control server connected to the network in response to receiving the identity information, where the request requests authentication for the end device. Authentication is received at the edge configuration device from the access control server for the end device to connect to a network connected to the edge configuration device. | 09-24-2015 |
Jonathan Selwyn Mead, London GB
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20130132837 | ENTERTAINMENT DEVICE AND METHOD - A method of administering a virtual dance floor for an entertainment device is provided. The virtual dance floor is part of an online virtual environment hosting multiple users each using a respective entertainment device. Each user is represented by an avatar. For each entertainment device, the method includes receiving, from an administrator of the online virtual environment, an indicator of music currently played on the virtual dance floor; initiating playback of the music from a locally stored copy in response to placement of the avatar of the respective user; detecting breakpoints in the currently played music; receiving from the administrator a music event signal; and in response to receiving the music event signal, selecting the next detected breakpoint in the currently played music and substituting that music at the selected breakpoint with a piece of music of a predetermined length that is substantially shorter than the currently played music. | 05-23-2013 |
Karl Mead, Grand Rapids, MI US
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20150359070 | Environment Optimization for Space Based On Presence and Activities - A method and system for facilitating at least first and second different activities within a first space that includes a first set of environmental control affordances including at least a first subset of lighting devices, the method comprising the steps of monitoring for triggers associated with the first space, when a trigger occurs, determining which of the first and second activities to facilitate, when the first activity is to be facilitated, controlling the environmental control affordances to present a first series of environments associated with the first activity and when the second activity is to be facilitated, controlling the environmental control affordances to present a second series of environments associated with the second activity. | 12-10-2015 |
Leonard Carl Mead, Walcott, ND US
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20150334915 | SEED BOOT MOUNTING - An apparatus includes a hinge mount top plate, a hinge mount bottom plate, and a pin connecting the top plate and bottom plate. A cam adjuster element includes a top aperture, a middle aperture, and a bottom aperture. A first fastener passes through the top aperture to connect the cam adjuster element to the hinge mount top plate. The first fastener may be disposed in different positions in the top aperture. A second fastener passes through the middle aperture to connect the cam adjuster element to the hinge mount top plate. The cam adjuster element may pivot about a longitudinal axis of the second fastener. The pin is retained in the bottom aperture. An assembly includes a disc, a seed boot, and a mounting mechanism that allows for movement between the seed boot and the disc about first pivot axis and second pivot axis. | 11-26-2015 |
Marcus Mead, Cornwall GB
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20110162739 | BLOCK ASSEMBLY FOR PNEUMATIC DISTRIBUTORS - The present invention relates to a block assembly ( | 07-07-2011 |
Oscar Edward Mead, Cowes GB
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20140322998 | MARINE HARNESS - A marine harness ( | 10-30-2014 |
Reginald Marshall Mead, Belgrade, MT US
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20160080524 | MOBILE RUNTIME CONDITIONAL SECTIONS FOR SURVEYS - Embodiments of the invention provide for dynamically generating an interface including conditional content based on runtime variables related to the device on which the content will be presented. Embodiments provide for creating and using runtime variables for showing or hiding data, depending on the type of device that the interface is accessed from. In other words, embodiments allow a designer of the interface to define conditional sections within the interface and the conditions, i.e., values of the runtime variables, upon which those section should be included or excluded from the interface. Based on the definition of these sections and the runtime values of variables associated with those sections, e.g., variables representing a device type, application type, mode, etc. of a client device on which the content will be presented, embodiments can provide an interface tailored to be presented on that type of device. | 03-17-2016 |
Richard Mead, Yorkshire GB
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20110251230 | THERAPEUTICS FOR NEUROLOGICAL DISORDERS - The present invention relates to therapeutic compounds that are Nrf2-ARE pathway activators suitable for the treatment of diseases known to be mediated by oxidative stress such as motor neurone disease. The invention also includes compounds identified by methods of the invention for treatment of neurogenerative diseases. | 10-13-2011 |
Richard James Mead, Sheffield GB
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20090191200 | Method for the Treatment of Multiple Sclerosis by Inhibiting IL-17 Activity - The present invention provides a method for the treatment and/or prophylaxis of multiple sclerosis (MS) comprising administering a therapeutically effective amount of an inhibitor of IL-17 activity. | 07-30-2009 |
Shaw Trevor Mead, Raglan NZ
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20090297270 | Artificial reef and a method of constructing an artificial reef - A method of constructing an artificial reef. The method includes attaching a reef element ( | 12-03-2009 |
Sherry Ellen Mead, San Francisco, CA US
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20150082219 | CONTEXTUALIZED REPORT BUILDING - A system and method for facilitating rendering a user interface display screen or portion thereof. An example method includes determining context information associated with a user, wherein the context information includes use job role information; and employing the context information to select one or more visualization types from a set of available visualization types. The method may further include using the context information to provide one or more first user options to select one or more categories of data pertaining to a business task; referencing the one or more categories to facilitate determining one or more data attributes, dimensions, or measures associated with the context information; utilizing the one or more data attributes and the context information to select the one or more visualization types from the set of available visualization types; and providing a second user option to choose a visualization type from among selected visualization types. | 03-19-2015 |
Simon Mead, London GB
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20160115536 | METHODS FOR ESTIMATING THE SIZE OF DISEASE-ASSOCIATED POLYNUCLEOTIDE REPEAT EXPANSIONS IN GENES - Methods for estimating the size of disease-associated polynucleotide repeat expansions in genes are disclosed which use restriction enzymes that do not cut within a repeat expansion and which are frequent cutting restriction enzymes that cut genomic DNA outside of the expansion into fragments of a size below the threshold capable of detection. A hybridisation probe that can bind to multiple sites within the expansion is then used to estimate its length and to correlate that to the diagnosis or prognosis of disease. | 04-28-2016 |
Tim Mead, Cambridgeshire GB
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20130197662 | COLLAGEN GEL FOR BONDING POROUS COLLAGEN-BASED MATERIALS WITH NON-POROUS COLLAGEN-BASED MATERIALS - The invention discloses a process for fabricating a biomaterial, comprising: a) joining a porous collagen based-material with a non-porous collagen based-material by applying a controlled amount of a bonding layer of a gel comprising collagen to a bonding surface of the non-porous collagen based-material, and contacting a surface of the porous collagen based-material with the gel applied to the bonding surface to partially hydrate a section of the porous material at the interface between the materials; b) drying the gel to dry to bond the materials together; and c) cross-linking the collagens in the bonding layer. Also disclosed are biomaterials and implants produced using the fabrication process. | 08-01-2013 |
Tim Mead, Cambridge GB
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20110009872 | IMPLANT DELIVERY DEVICE AND METHOD - An implant delivery device ( | 01-13-2011 |
William J. Mead, Paris CA
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20100192618 | EVAPORATOR ASSEMBLY - An evaporator assembly through which a refrigerant is circulated to transfer heat out of a volume of air in a housing in which the evaporator assembly is at least partially disposed. The evaporator assembly includes an evaporator in fluid communication with a compressor for compressing the refrigerant, a solenoid valve subassembly for controlling circulation of the refrigerant, a thermostat electrically connectable to the solenoid valve subassembly via a solenoid control circuit, one or more fans for circulating the air in the housing, and one or more fan motors for rotating the fans. Drive voltage supplied to the fan motors is controlled by a fan controller. The fan controller provides a first predetermined drive voltage to the motor drive when refrigerant is circulatable and a second predetermined drive voltage to the motor drive when refrigerant is non-circulatable. | 08-05-2010 |
20140075971 | METHOD OF OPERATING AN EVAPORATOR ASSEMBLY WITH A FAN CONTROLLER - A method of operating an evaporator assembly in which a refrigerant is circulatable to transfer heat out of air in a housing. The evaporator assembly includes a thermostat that completes a solenoid control circuit when the temperature of the air in the housing is above a predetermined cut-in temperature, and opens the solenoid control circuit when the temperature of the air is below a predetermined cut-out temperature. The thermostat completes a fan control circuit when the solenoid control circuit is open, and opens the fan control circuit when the solenoid control circuit is completed. A fan controller detects a signal voltage when the fan control circuit is completed, and provides a first predetermined drive voltage to a fan motor drive. Upon the fan controller failing to detect the signal voltage, a second predetermined drive voltage being greater than the first predetermined drive voltage is provided to the motor drive. | 03-20-2014 |
20150128624 | CONDENSER ASSEMBLY WITH A FAN CONTROLLER AND A METHOD OF OPERATING SAME - A condenser assembly through which a refrigerant is circulated to transfer heat from the refrigerant to ambient air in which the condenser assembly is at least partially disposed. The condenser assembly includes a compressor, a crankcase heater energizable via a crankcase heater control circuit, a condenser, a condenser fan, and an electronically commutated condenser fan motor. The condenser assembly also includes an ambient temperature sensor for sensing at least one temperature of the ambient air, to provide a sensed temperature. The condenser assembly includes a condenser switch subassembly configured to control energization of the crankcase heater and the condenser fan motor. The condenser switch subassembly is controlled by the ambient temperature sensor. The condenser fan motor is controlled by a condenser fan controller that applies a first voltage or a second voltage to the condenser fan motor depending on whether a third conductor attached to the motor is energized. | 05-14-2015 |