Patent application number | Description | Published |
20100190978 | METHYLENE BLUE - CURCUMIN ANALOG FOR THE TREATMENT OF ALZHEIMER'S DISEASE - A methylene blue-curcumin hybrid useful in treating Alzheimer's Disease. | 07-29-2010 |
20100268151 | Intracranial Implant Emitting Light Between 450 nm and 600 nm - An intracranial implant emitting light having a wavelength between blue and yellow light | 10-21-2010 |
20100317948 | Photocatalytic Implant Having a Sensor - An implant comprises a photocatalytic layer on at least one surface and is adapted to act as a sensor. In some embodiments, the photocatalytic layer is a semiconductor oxide that is doped. According to some embodiments, the implant comprises a wave guide. According to some embodiments the implant comprises a light port. According to some embodiments, the implant comprises a reflective material on a surface of the waveguide. According to some embodiments the implant comprises a composite material comprising a first material that has a transmissivity when exposed to a predetermined wavelength of light and a second material that has photocatalytic activity when exposed to the predetermined wavelength of light. According to some embodiments the implant comprises a light source adapted to irradiate the photocatalytic surface. | 12-16-2010 |
20110077655 | Vertebral Body Spool Device - A mandrel is inserted into the tissue to be distracted and a filament is repeatedly wrapped around the mandrel to make a spool. As the mandrel turns, the filament coils around the mandrel to create of spool of increasing diameter. This spool can be used as a distractor, tamp, or implant. A spool implant can be cemented to further stabilize the device in situ, such as a vertebral body. The filament deposition upon the mandrel is controlled by rotation and the volume creation is incremental. This makes the spool ideal for creating highly controlled distraction forces or insertion of bulking material. In some embodiments, fibers having a low glass transition temperature are used. | 03-31-2011 |
20110097377 | Methods and Devices for Correcting Spinal Deformity With Pharmaceutical-Eluting Pedicle Screws - A method of correcting spinal deformity, which includes locating pharmaceutical-loaded implants adjacent to targeted spinal growth plates, and then eluting the pharmaceutical onto the growth plates. Preferably, the method involves correcting spinal deformity by simply inserting a pharmaceutical-eluting pedicle screw onto the concave side of a scoliotic curve. In some embodiments, the screw has a cannulated internal reservoir that contains a growth-inhibiting pharmaceutical (such as a tetracycline) and at least one fenestration that allows the pharmaceutical to elute onto the vertebral body growth plate. | 04-28-2011 |
20110130392 | Method of Administering a Methylene Blue - Curcumin Analog for the Treatment of Alzheimer's Disease - A method of administering a methylene blue-curcumin hybrid useful in treating or preventing Alzheimer's Disease. | 06-02-2011 |
20110257432 | Metformin-Cysteine Prodrug - A metformin-cysteine prodrug. It is believed that the prodrug of the present invention will transport in the LAT1 and LAT2 transporter system. Because the LAT1 and LAT2 transporters are important and effective transporters of amino acids in both the small intestine and colon, it is believed that the LAT-transportable prodrugs of the present invention will be effectively absorbed both in small intestine and in the colon. The increased absorption window provided by the present invention should result in highly sustained plasma concentrations of metformin, thereby increasing the effectiveness of the medication and allowing for a single daily dose. | 10-20-2011 |
20110257587 | Iontophoretic Delivery of Curcumin and Curcumin Analogs for the Treatment of Alzheimers Disease - A device for iontophoretically delivering a charged curcuminoid across the skin of an Alzheimer's Disease patient. | 10-20-2011 |
20110319878 | Red Light Implants for Treating Postpartum Depression - Irradiating an orbitofrontal cortex of a patient having postpartum depression with red/near infrared light in order to increase metabolism, bcl-2 and BDNF in the patient's orbitofrontal cortex. | 12-29-2011 |
20120259172 | Instrument Adaptor for Image Guided Surgery - The invention relates to an adaptor for tracking an instrument location during image guided surgery. The adaptor has a drive shaft, a proximal handle and a distal instrument tip. The drive shaft has a linear proximal portion, a curved mid-portion and a linear distal portion that is co-linear with the linear proximal portion. Three tracking elements (such as reflective balls) are placed on the sinusoidal portion. When the handle is rotated, the two linear portions remain fixed on the longitudinal axis, but the tracking elements on the sinusoidal portion travel in orbits about the longitudinal axis, thereby allowing a computer to track the location of the instrument tip. | 10-11-2012 |
Patent application number | Description | Published |
20090204058 | Device For Removing Deleterious Charged Molecules From Brain Tissue - Methods and devices for removing cationic glutamate or anionic aluminum complexes from brain tissue by applying a voltage to the brain tissue. | 08-13-2009 |
20090324558 | Transdiscal administration of cycline compounds - The present invention relates to administering a doxycycline compound into a diseased intervertebral disc. | 12-31-2009 |
20090326275 | USE OF NITROGEN-CONTAINING CURCUMIN ANALOGS FOR THE TREATMENT OF ALZHEIMERS DISEASE - A curcumin analog in which natural curcumin is modified by an amino acid moiety that increases the analog's transport across the blood brain barrier by the LAT1 transporter. | 12-31-2009 |
20100198316 | Intracranial Red Light Treatment Device For Chronic Pain - Placement of a silicone tube in the cerebral aqueduct and the transmission of red light through it, resulting in the irradiation and consequent biostimulation of the adjacent periaqueductal gray, thereby causing the release of endorphins therefrom and pain relief. | 08-05-2010 |
20100249795 | Cervical Motion Disc Inserter - A novel inserter for inserting a prosthetic cervical motion disc, wherein the distal end portion of the inserter features a pair of projections that are adapted to move slidably and transversely relative to one another (like a wrench) in order to engage a prosthetic cervical motion disc. | 09-30-2010 |
20100286585 | Shunt Delivery of Curcumin - A method for reducing or preventing a human brain disorder relating to the presence of a pathogenic substance in cerebrospinal fluid by selecting a human for treatment as a patient and placing a proximal end of a first catheter, having at least a first lumen, in a first sub-dural location within the brain of the patient to establish open communication between the first lumen and cerebrospinal fluid of the patient. For an extended period of time, a curcumin agent selected from at least one of curcumin, a curcumin hybrid and a curcumin analog is delivered to the cerebrospinal fluid to interact with the pathogenic substance to attenuate its effect on the brain. | 11-11-2010 |
20100292512 | Methylated Curcumin-Resveratrol Hybrid Molecules for Treating Cancer - Methylated curcumin-methoxystilbene hybrid molecules that have particular use in treating cancer. | 11-18-2010 |