Patent application number | Description | Published |
20110238610 | SYSTEM AND METHOD FOR EFFICIENT REASONING USING VIEW IN DBMS-BASED RDF TRIPLE STORE - An efficient reasoning system and method using a view in a DBMS-based RDF triple store are provided. The DBMS-based reasoning system includes a triple input unit for receiving a Resource Description Framework (RDF) triple. A triple examination unit examines whether the received triple conforms to RDFS subsumption relation entailment rules or Web Ontology Language (OWL) inverse relation rules. A view creation unit creates a table view when the received triple conforms to the RDFS subsumption relation entailment rules or the OWL inverse relation rules as a result of the examination. A triple storage unit stores the received triple. The DBMS-based triple store can efficiently perform reasoning based on rule rdfs7 or rdfs9, which is included in the RDFS subsumption relation entailment rules, and the OWL inverse relation rules. | 09-29-2011 |
20110246461 | RELATED SEARCH SYSTEM AND METHOD BASED ON RESOURCE DESCRIPTION FRAMEWORK NETWORK - Related search service system and method based on the RDF network are provided. The related search service method includes: extracting a subject, a predicate, and an object from a text document composed of the unstructured sentences not having the structured format; creating RDF models composed of the extracted one subject, one predicate, and one object: determining whether there is semantic collision by comparing the RDF models; constructing an RDF network by separating the RDF models when there is semantic collision in the RDF models, and integrating the RDF models when there is no semantic collision; and providing service for searching the subjects or the objects which have the same predicate on the basis of the created RDF network. | 10-06-2011 |
20110258230 | QUESTION-ANSWER SERVICE SYSTEM AND METHOD BASED ON RDF SEARCH - Question-answer service system and method based on RDF search are provided. The question-answer service method includes: extracting a subject. a predicate, and an object from a text document composed of the unstructured sentences not having the structured format; creating RDF models composed of the extracted one subject, one predicate, and one object; determining whether there is semantic collision by comparing the RDF models; receiving a question including the subject S, the predicate P, or the object O from a user and being requested to search, on the basis of the constructed RDF network; creating a question for search by interpreting the input question;. searching an RDF model matching with the question for search through the RDF network; and providing a subject S, a predicate P, or an object O. which corresponds to an answer for the question from the searched RDF model. | 10-20-2011 |
20110270882 | RESOURCE DESCRIPTION FRAMEWORK NETWORK CONSTRUCTION DEVICE AND METHOD USING AN ONTOLOGY SCHEMA HAVING CLASS DICTIONARY AND MINING RULE - RDF network construction device and method using an ontology schema having class dictionaries and mining rules are provided. The RDF network construction device includes an ontology schema storing module, a class managing module, a mining rule managing module, a mining pattern creating module, and an RDF triple creating module. | 11-03-2011 |
20110320490 | NAMED ENTITY DATABASE OR MINING RULE DATABASE UPDATE APPARATUS AND METHOD USING NAMED ENTITY DATABASE AND MINING RULE MERGED ONTOLOGY SCHEMA - An apparatus and method for updating a named entity dictionary or a mining rule database using the named entity dictionary and a mining rule combined with an ontology schema is provided. The apparatus includes a named entity dictionary and mining rule database storage module storing the named entity dictionary and a mining rule database; a mining pattern generation module recognizing a terminology from a text and converting the terminology into the mining pattern; a named entity and mining rule search module searching for a corresponding named entity and a mining rule from the named entity dictionary and the mining rule database using the recognized terminology and the mining pattern; and a named entity dictionary update module estimating a named entity of the terminology using the mining rule and storing the estimated named entity of the terminology in the named entity dictionary depending on a user's selection. | 12-29-2011 |
20110320491 | MODULE AND METHOD FOR SEARCHING NAMED ENTITY OF TERMS FROM THE NAMED ENTITY DATABASE USING NAMED ENTITY DATABASE AND MINING RULE MERGED ONTOLOGY SCHEMA - A module and method for determining a named entity of a terminology using a named entity dictionary and a mining rule combined with an ontology schema is provided. The module includes a named entity dictionary and mining rule database storing the named entity dictionary and a mining rule database; a mining pattern generation unit recognizing a terminology from a text and converting the terminology into a mining pattern; a named entity and mining rule search unit searching for a corresponding named entity and a mining rule respectively from the named entity dictionary and the mining rule database using the recognized terminology and the mining pattern; and a names entity selection unit selecting, if two or more named entities corresponding to the recognized terminology are searched, a named entity matching to the concept configuring the RDF triple of the searched mining rule as a named entity of the terminology among the searched named entities. | 12-29-2011 |
20110320505 | PERSONALIZING SERVICE SYSTEM AND METHOD BASED ON ONTOLOGY - A personalized service system and method based on an ontology is provided, in which if a user selects a personalized service while a subject or an object in a user profile ontology of user's personal information is associated with a subject or an object of a personalized service ontology through a relationship name, the system and method searches for a personalized service ontology corresponding to the selected personalized service, acquires personal information of an instance form in the user profile ontology associated with the personalized service ontology, executes the personalized service by applying the acquired personal information, and provides the user with a result of the execution. | 12-29-2011 |
20120059908 | SEMANTIC SERVICE APPLYING SYSTEM AND METHOD - The present invention relates to a semantic service applying system and a method, comprising: a semantic service pipeline manager which demands and receives a particular semantic service pipeline to and from a semantic service server, and stores the corresponding pipeline in a database to manage the stored pipeline; a semantic service pipeline provider which extracts corresponding semantic service pipelines and sends the extracted pipelines to the corresponding service server if the user requests at least one of a plurality of semantic service pipelines to be provided; and a database which stores information associated with a semantic service pipeline providing server as well as the semantic service pipelines, and thus various ontology-based semantic services can be applied to the web. | 03-08-2012 |
20120059926 | SYSTEM AND METHOD FOR SEMANTIC SERVICE - A method and system for semantic services for registering and managing semantic services by collecting the semantic services distributed among a plurality of service servers, and combining the plurality of semantic services to be matched with a condition set by a user are provided. The system includes a semantic service management server which registers, deletes, and edits the ontology and ontology-based semantic service information, and supports an information searching function performed by a semantic broker server; the semantic broker server which searches and combines semantic services through the semantic service management server, and provides the results with one of the combined semantic services or semantic workflows; and a semantic service license server which requests the results by transmitting the corresponding condition to the semantic broker server when the user inputs the condition as well as an input factor according to the preset items, and receives and outputs the corresponding results. | 03-08-2012 |
20120233213 | NAMED ENTITY DATABASE OR MINING RULE DATABASE UPDATE APPARATUS AND METHOD USING NAMED ENTITY DATABASE AND MINING RULE MERGED ONTOLOGY SCHEMA - A mining rule database update apparatus using a named entity dictionary and a mining rule combined with an ontology schema includes: a named entity dictionary and mining rule database storage module storing the named entity dictionary and a mining rule database; a mining pattern generation module recognizing terminology from text and converting the terminology into the mining pattern; a named entity and mining rule search module searching for a corresponding named entity and a mining rule from the named entity dictionary and the mining rule database using the recognized terminology and the mining pattern; and a mining rule database update module estimating a relationship name using a named entity of the recognized terminology and the ontology schema, generating a corresponding mining rule, and storing the generated mining rule in the mining rule database depending on a user's selection. | 09-13-2012 |
20120233214 | NAMED ENTITY DATABASE OR MINING RULE DATABASE UPDATE APPARATUS AND METHOD USING NAMED ENTITY DATABASE AND MINING RULE MERGED ONTOLOGY SCHEMA - A mining rule database update apparatus using a named entity dictionary and a mining rule combined with an ontology schema includes: a named entity dictionary and mining rule database storage module storing the named entity dictionary and a mining rule database; a named entity and mining rule search module searching for a corresponding mining rule and a named entity from the mining rule database and the named entity dictionary using a terminology included in an inputted mining pattern and the mining pattern; and a mining rule database update module estimating a relationship name using a named entity of the terminology and the ontology schema, generating a corresponding mining rule, and storing the generated mining rule in the mining rule database depending on user's selection. | 09-13-2012 |
20120271789 | APPARATUS AND METHOD FOR PREDICTION DEVELOPMENT SPEED OF TECHNOLOGY - A developing speed estimation apparatus includes: bibliographic database integrating heterogeneous resources; feature-set creation module calculating feature values of predefined features by searching the bibliographic database, and creating a feature-set of each technology using the feature values, for technologies on technology lifecycle; answer feature-set creation module calculating common feature values of feature sets of technologies belonging to the same stage in the technology lifecycle and creating answer feature-set of each stage; year-specific stage determination module that, if specific technology is inputted, acquires feature-related information for predetermined features by searching the bibliographic database for the specific technology, creates year-specific feature-set using the feature-related information, and determines year-specific stage of the specific technology by comparing the year-specific feature-set with the answer feature-set; and developing-speed estimation module estimating the developing speed of the specific technology using the year-specific stage. | 10-25-2012 |
20120271841 | APPARATUS AND METHOD FOR VISUALIZING TECHNOLOGY CHANGE - A technology transition visualization apparatus includes: bibliographic database integrating heterogeneous resources; technology information database storing information in technology lifecycle; interface module receiving technology from user; feature set creation module calculating feature values by searching bibliographic database and creating feature set for each technology; answer feature set creation module calculating common feature value of feature sets of technologies belonging to the same stage in technology lifecycle and creating answer feature set of each stage; stage determination module acquiring feature-related information, creating representative feature set and year-specific feature set of technology, determining representative stage or year-specific stage by comparing the representative feature set or year-specific feature set with the answer feature set, and estimating development speed of the technology; visualization module visualizing the technology lifecycle; and year-specific stage acquisition module acquiring current stage, year-specific stage and estimated next stage of the technology and visualizing the stages. | 10-25-2012 |
20120271846 | APPARATUS AND METHOD FOR STAGE JUDGEMENT USING OF TECHNOLOGY LIFE CYCLE - A stage determination apparatus including storage and processor includes: a bibliographic database integrating heterogeneous resources; a feature-set creation module calculating feature values of predefined features by searching the bibliographic database, and creating a feature-set of each technology using the feature values, for technologies on technology lifecycle; an answer feature-set creation module calculating a common feature value of feature sets of technologies belonging to the same stage in the technology lifecycle and creating an answer feature-set of each stage; a stage determination module that, if a technology is inputted, acquires feature values and creates a feature-set for predefined features by searching the bibliographic database for the technology, compares a corresponding feature value in the feature-set of the technology with a feature value according to a feature selection flow in a previous decision tree according to the feature selection flow, and determines a stage having a feature value finally selected according to the feature selection flow as a stage where the technology belongs to in the technology lifecycle. | 10-25-2012 |
Patent application number | Description | Published |
20100141531 | POSITION TRACKING APPARATUS AND METHOD FOR A LOW POWER WPAN/WBAN DEVICE - Provided is a position tracking apparatus and method for low power WPAN/WBAN sensors in a sensor network. A position tracking apparatus collects distance information of adjacent nodes from a plurality of anchor nodes whose positions are known and at least one sensor node whose position is not known, in a sensor network, calculates the shortest path for the anchor node based on the collected distance information of the adjacent node, and classifies nodes into nodes of a first group whose positions are known and nodes of a second group whose positions are not known to select sensor nodes in an adjacent order from the second group to the first group based on the anchor node and detect the positions thereof. | 06-10-2010 |
20110268155 | DISTANCE ESTIMATION APPARATUS, SYSTEM AND METHOD USING RANGING COUNTER - Provided is a distance estimation apparatus, system and method for accurately estimating the distance between TX/RX devices by means of low-end hardware in a communication system such as the IEEE 802.15.4a system. The distance estimation apparatus includes an analog-to-digital converter, a parallelizer, a parallel synchronization means, a counter, and a system clock generator. The analog-to-digital converter analog-to-digital converts a received packet signal to generate a serial digital signal, and the parallelizer 1:N parallelizes the serial digital signal. The parallel synchronization means includes an N number of buffers for receiving the output of the parallelizer. A counter outputs a count value for estimation of the propagation delay time of a UWB signal on the basis of the sampling data retained in the parallel synchronization means. The system clock generator generates a system clock in the distance estimation apparatus. Therefore, it is possible to accurately estimate the distance between the TX/RX devices by arithmetically calculating a received signal while operating a ranging counter with a low-rate system clock, thereby simplifying the hardware structure and minimizing power consumption. | 11-03-2011 |
20130043920 | DIGITAL PHASE-LOCKED LOOP APPARATUS USING FREQUENCY SHIFT KEYING AND METHOD OF CONTROLLING THE SAME - A digital phase-locked loop apparatus using FSK includes a PFD detecting phase differences between a reference clock and a frequency-divided signal, and a first adder for generating first digital control codes by adding first digital codes, second digital codes, and channel frequency codes including channel information to each other, the first digital codes being converted from time differences between first and second pulses. The apparatus further includes a digital filter correcting errors of the first digital control codes to generate second digital control codes, a DCO for varying an oscillating frequency in accordance with a digital tuning word based on the second digital control codes, and a dual modulus division unit dividing the oscillating frequency into a frequency-divided signal. | 02-21-2013 |
20130058360 | METHOD OF GENERATING AND RECEIVING PACKETS IN LOW ENERGY CRITICAL INFRASTRUCTURE MONITORING SYSTEM - A method of generating a packet for low energy critical infrastructure monitoring (LECIM) wireless communication is provided. The method includes steps of generating a first bit string by multiplexing a physical layer header (PHR) bit and a physical layer service data unit (PSDU) bit; convolution encoding the first bit string; interleaving the convolution-encoded first bit string; generating a second bit string by multiplexing the interleaved first bit string with a synchronization header (SHR) bit; and modulating the second bit string with a frequency shift keying (FSK) method and a position-based FSK method. | 03-07-2013 |
20130070750 | METHOD AND APPARATUS FOR ACQUIRING RECEPTION SYNCHRONIZATION IN LOCAL WIRELESS COMMUNICATION SYSTEM - In a local wireless communication system, a reception signal including an STF (short training field) in which a plurality of patterns are repeatedly transmitted is received, the STF including a first number of STF patterns and a second number of STF patterns, the second number of STF patterns having an opposite code to that of the first number of STF patterns. In a first frequency offset estimation and correction process and a second frequency offset estimation and correction process, frequency offset estimation is performed on a plurality of STF patterns to acquire a phase error of each sample constituting the STF patterns, and the frequency of the STF patterns is corrected based on the acquired phase error. Cross correlation is performed on a predetermined number of STF patterns, among a plurality of STF patterns output subsequent to the frequency offset estimation and correction, to detect frame timing. | 03-21-2013 |
20130303091 | METHOD AND APPARATUS FOR TRANSMITTING AND RECEIVING HIGH FREQUENCY - A high frequency transmitting and receiving apparatus of a wireless communication system low-noise amplifies a signal that is received from a transmitting and receiving antenna through a low noise amplifier in a reception mode, and amplifies a signal be transmitted through a power amplifier in a transmission mode and transmits the signal through the transmitting and receiving antenna, and the high frequency transmitting and receiving apparatus is connected between the transmitting and receiving antenna and the low noise amplifier and turns on a switch in a reception mode and turns off the switch in a transmission mode, thereby separating transmitting and receiving signals. | 11-14-2013 |
20140016653 | METHOD OF GENERATING PACKET, METHOD OF TRANSMITTING PACKET, AND METHOD OF RANGING OF PHYSICAL LAYER TRANSMITTER OF WIRELESS PERSONAL AREA NETWORK SYSTEM - A method of generating a packet of a physical layer transmitter of a TV white space (TVWS) wireless personal area network (WPAN) system operating a WPAN service in TVWS is provided. A packet that is generated by the method of generating the packet includes a preamble, a start frame delimiter that is positioned after the preamble, a first physical layer header that is positioned after the start frame delimiter, and a physical layer service data unit that is positioned after the first physical layer header. Here, the first physical layer header represents whether the packet is a ranging packet for ranging, and includes a ranging packet identification bit corresponding to a reserved bit of the second physical layer header in a SUN system and a LECIM system, and a parity bit. | 01-16-2014 |
20140023164 | RECEIVING APPARATUS AND METHOD IN SMART UTILITY NETWORK COMMUNICATION SYSTEM - A receiving apparatus receives an FSK signal, converts the FSK signal into a phasor including amplitude and phase, estimates and compensates for a CFO (carrier frequency offset) from the converted phasor, and recovers a data bit from the converted phasor. | 01-23-2014 |
20140301412 | METHOD OF CREATING PREAMBLE, AND METHOD AND APPARATUS FOR DETECTING FRAME BOUNDARY - A method and apparatus of detecting a frame boundary by using a preamble are provided. The method includes delaying the preamble by a predetermined length of time, wherein the preamble includes an LTF and a code of the (n+1)th one of 2n sync sequences of the LTF is the inverse of a code of the last one of the sync sequences of STF; calculating a correlation value between the preamble and the delayed preamble; and detecting a frame boundary by comparing the correlation value with a threshold correlation value. | 10-09-2014 |
20150201296 | METHOD AND APPARATUS FOR TRANSMITTING WIRELESS PERSONAL AREA NETWORK COMMUNICATION SYSTEM - A transmitting apparatus of a WPAN communication system generates a synchronization header, a physical layer header, and a physical layer service data unit, multiplexes the synchronization header and the physical layer header into a bit stream and then modulates the multiplexed bit stream by a first differential phase modulation scheme, modulates the physical layer service data unit by a second differential phase modulation scheme, and multiplexes and transmits a symbol modulated by the first differential phase modulation scheme and a symbol modulated by the second differential phase modulation scheme into a symbol stream. | 07-16-2015 |
Patent application number | Description | Published |
20100254486 | METHOD OF BLOCK-CODED GROUP MODULATION AND TRANSMITTER USING THE SAME - A transmitter using a method of block code-based group modulation includes a grouping unit, a generating unit, and a mapping unit. The grouping unit generates symbols by grouping a data bit stream into N-bit groups, and the generating unit generates a codeword set composed of codewords corresponding to combinations of arrangements of pulses that are generated by a result of grouping to a predetermined number. Next, the mapping unit block-maps a codeword selected from the codeword set to groups constituting the symbols. | 10-07-2010 |
20110116568 | BLOCK-CODED GROUP MODULATION METHOD AND TRANSMITTER/RECEIVER USING THE SAME - A block-coded group modulation method includes generating a symbol by grouping at least one bit of a data bit stream into one group, classifying the symbol into an n number of sections, and generating an n number of initial information bits. Next, the method includes setting up the size of a pulse corresponding to signal energy transmitted through each of the n sections, generating an additional information bit on the basis of the number of cases according to the sequence of the energy sizes, and generating final information bits by inserting the additional information bit into the initial information bits. | 05-19-2011 |
20120163263 | BASE STATION, TERMINAL, AND OPERATING METHOD THEREOF - A base station and a terminal for supporting a low power mode are provided. The base station transmits a first type of beacon signal for a terminal operating in a normal mode, a second type of beacon signal for a terminal operating in a low power mode, and a charging signal for a terminal in a low power mode. The terminal harvests energy from a charging signal and receives the second type of beacon signal using the harvested energy. The terminal confirms a communication request through the second type of beacon signal, enters into an active period, and communicates with the base station. | 06-28-2012 |
20120163444 | APPARATUS AND METHOD FOR TRANSMITTING AND RECEIVING - A transmitting apparatus groups a data bit sequence to groups each formed of a predetermined number of bits, modulates predetermined bits of one of groups through a frequency shift keying (FSK) modulation method, non-continuously aligns the FSK modulation signals, and transmits the non-continuous FSK modulation signals. | 06-28-2012 |
Patent application number | Description | Published |
20090268241 | METHOD OF CONTROLLING A PRINT JOB AND A TERMINAL DEVICE USING THE SAME - A method of controlling a print job using a universal print driver of a terminal device connectable to a plurality of image forming apparatuses. The method can include selecting one of the plurality of image forming apparatuses, selecting pre-stored printing options of the plurality of image forming apparatuses, determining whether the pre-stored printing options are available on the image forming apparatus for which the universal print driver is selected, and displaying that the pre-stored printing option is unavailable, if at least one of the pre-stored printing options is unavailable. Therefore, a user can easily recognize information regarding unavailable pre-stored printing options. | 10-29-2009 |
20100073693 | METHOD OF CONTROLLING SCALED-DOWN PRINTING FOR HOST DEVICE AND THE HOSE DEVICE USING THE METHOD - A method of controlling scaled-down (size-reduced) printing for a host device and the host device using the method, the method including inputting a scaling-down mode for the print document through a user interface (UI) of the host device; inputting a scaling-down rate fine adjustment for the scaling-down mode to generate a new scaling-down rate; and applying the new scaling-down rate to the print document. Thus, a user is provided with the convenience of obtaining a scaled-down print result that is not distorted. | 03-25-2010 |
20120212758 | PRINTING CONTROL TERMINAL DEVICE AND PRINTING CONTROL METHOD - A printing control terminal device including an input unit to receive a printing order to request a printing operation for a printing work, a communication interface unit to receive information regarding a resource saving mode from an image forming apparatus, a display unit to display information regarding the received resource saving mode, a printer driver unit to generate printing data for the printing work, and a controller to control the communication interface unit to transmit the generated printing data to the image forming apparatus. | 08-23-2012 |
Patent application number | Description | Published |
20100133545 | THIN FILM TRANSISTOR AND METHOD OF FABRICATING THE SAME - A thin film transistor includes a multi-coaxial silicon nanowire unit including a plurality of coaxial silicon nanowires on a substrate, the multi-coaxial silicon nanowire unit including a central portion and end portions of the central portion; a gate electrode on the central portion; and a source electrode and a drain electrode on the respective end portions, respectively, so as to electrically connect to the multi-coaxial silicon nanowire unit. | 06-03-2010 |
20100163850 | THIN FILM TRANSISTOR AND METHOD OF FABRICATING THE SAME - A thin film transistor includes: a silicon nanowire on a substrate, the silicon nanowire having a central portion and both side portions of the central portion; a gate electrode on the central portion; and a source electrode and a drain electrode spaced apart from the source electrode on the both side portions, the source electrode and the drain electrode electrically connected to the silicon nanowire, respectively. | 07-01-2010 |
20120009707 | THIN FILM TRANSISTOR AND METHOD OF FABRICATING THE SAME - A thin film transistor includes a multi-coaxial silicon nanowire unit including a plurality of coaxial silicon nanowires on a substrate, the multi-coaxial silicon nanowire unit including a central portion and end portions of the central portion; a gate electrode on the central portion; and a source electrode and a drain electrode on the respective end portions, respectively, so as to electrically connect to the multi-coaxial silicon nanowire unit. | 01-12-2012 |
20120248449 | THIN FILM TRANSISTOR AND METHOD OF FABRICATING THE SAME - A thin film transistor includes a multi-coaxial silicon nanowire unit including a plurality of coaxial silicon nanowires on a substrate, the multi-coaxial silicon nanowire unit including a central portion and end portions of the central portion; a gate electrode on the central portion; and a source electrode and a drain electrode on the respective end portions, respectively, so as to electrically connect to the multi-coaxial silicon nanowire unit. | 10-04-2012 |
Patent application number | Description | Published |
20090104749 | Methods of Manufacturing Semiconductor Devices Having Contact Plugs in Insulation Layers - Methods of manufacturing semiconductor devices are provided in which a first contact plug is formed on a first active region in a substrate and a second contact plug is formed on a second active region in the substrate. A height of an upper surface of the second contact plug from the substrate is greater than a height of an upper surface of the first contact plug from the substrate. A third contact plug is formed on the second contact plug. A first spacer is formed on a side surface of the third contact plug. A third interlayer insulation layer is formed that covers the third contact plug. The third interlayer insulation layer is patterned to form a third opening that exposes the first contact plug. A fourth contact plug is formed in the third opening that is electrically connected to the first contact plug. | 04-23-2009 |
20100173028 | PROCESS FOR PREPARING VITIS VINIFERA PIP EXTRACT AND PHARMACEUTICAL COMPOSITION FOR PREVENTING OR TREATING RHEUMATOID ARTHRITIS COMPRISING THE SAME - The present invention provides an improved process for preparing a | 07-08-2010 |
20100210087 | Methods of Manufacturing Semiconductor Devices Having Contact Plugs in Insulation Layers - Methods of manufacturing semiconductor devices are provided in which a first contact plug is formed on a first active region in a substrate and a second contact plug is formed on a second active region in the substrate. A height of an upper surface of the second contact plug from the substrate is greater than a height of an upper surface of the first contact plug from the substrate. A third contact plug is formed on the second contact plug. A first spacer is formed on a side surface of the third contact plug. A third interlayer insulation layer is formed that covers the third contact plug. The third interlayer insulation layer is patterned to form a third opening that exposes the first contact plug. A fourth contact plug is formed in the third opening that is electrically connected to the first contact plug. | 08-19-2010 |
20130017226 | TNF-A and TWEAK Dual Antagonist for the Prophylaxis and Treatment of Autoimmune DiseasesAANM Park; Young WooAACI DaejeonAACO KRAAGP Park; Young Woo Daejeon KRAANM Jo; Ki WonAACI Gyeonggi-doAACO KRAAGP Jo; Ki Won Gyeonggi-do KRAANM Yoo; Srok HoAACI DaejeonAACO KRAAGP Yoo; Srok Ho Daejeon KRAANM Yu; JungAACI DaejeonAACO KRAAGP Yu; Jung Daejeon KRAANM Kim; Dong JiAACI DaejeonAACO KRAAGP Kim; Dong Ji Daejeon KRAANM Yoon; Sun-HaAACI DaejeonAACO KRAAGP Yoon; Sun-Ha Daejeon KRAANM Song; Eun JungAACI DaejeonAACO KRAAGP Song; Eun Jung Daejeon KRAANM Lee; Eun KyungAACI Gyeonggi-doAACO KRAAGP Lee; Eun Kyung Gyeonggi-do KRAANM Oh; Jin MiAACI Gyeonggi-doAACO KRAAGP Oh; Jin Mi Gyeonggi-do KRAANM Cho; Kyu WonAACI SeoulAACO KRAAGP Cho; Kyu Won Seoul KRAANM Cho; Mi LaAACI SeoulAACO KRAAGP Cho; Mi La Seoul KRAANM Kim; Ho YounAACI SeoulAACO KRAAGP Kim; Ho Youn Seoul KRAANM Park; Mi KyungAACI Gyeonggi-doAACO KRAAGP Park; Mi Kyung Gyeonggi-do KRAANM Oh; Hye JwaAACI SeoulAACO KRAAGP Oh; Hye Jwa Seoul KRAANM Park; Jin SilAACI SeoulAACO KRAAGP Park; Jin Sil Seoul KRAANM Woo; Yun JuAACI SeoulAACO KRAAGP Woo; Yun Ju Seoul KRAANM Byun; Jae KyeongAACI Chungcheongbuk-doAACO KRAAGP Byun; Jae Kyeong Chungcheongbuk-do KRAANM Ryu; Jun GeolAACI Gangwon-doAACO KRAAGP Ryu; Jun Geol Gangwon-do KR - The present invention relates to TNFR2-TWEAKR fusion protein, more precisely to TNFR2-TWEAKR fusion protein acting as a double-antagonist to TNF-α and TWEAK, known as major causes of autoimmune arthritis which is one of autoimmune diseases. When the composition comprising TNFR2-TWEAKR fusion protein was treated to Th17 cells, the secretion of the inflammatory cytokine IL-17 was reduced but the secretion of the anti-inflammatory cytokine IL-10 generated in Treg cells was increased. Such effect of TNFR2-TWEAKR fusion protein was far greater than that of a single protein such as TNFR2-Fc or TWEAK-Fc. The TNFR2-TWEAKR fusion protein of the present invention has not only excellent treatment effect on arthritis in CIA mouse model not also excellent treatment effect on autoimmune rheumatoid arthritis by increasing the expression of Treg, the immune suppressive cells. Therefore, the TNFR2-TWEAKR fusion protein of the present invention can be effectively used as an active ingredient for the composition for the prevention and treatment of autoimmune disease. | 01-17-2013 |
20130022642 | Dual Antagonist for TNF-A and IL-21 for Preventing and Treating Autoimmune Diseases - The present invention relates to TNFR2-IL21R fusion protein acting as a double-antagonist to TNF-alpha (α) and IL-21. The composition containing the double antagonist to TNF-α and Il-21 (TNFR2-IL21R fusion protein), known as major causes of autoimmune rheumatoid arthritis, one of autoimmune diseases, can reduce the secretion of inflammatory cytokine, increase the secretion of anti-inflammatory cytokine, and suppress the differentiation of osteoclasts better than single proteins such as TNFR2-Fc and IL21R-Fc. The TNFR2-IL21R fusion protein of the present invention has not only excellent treatment effect on arthritis in CIA mouse model not also excellent treatment effect on autoimmune rheumatoid arthritis by increasing the expression of Treg, the immune suppressive cells. Therefore, the TNFR2-IL21R fusion protein of the present invention can be effectively used as an active ingredient for the composition for the prevention and treatment of autoimmune disease. | 01-24-2013 |
20130228750 | THIN FILM TRANSISTOR METHOD OF FABRICATING THE SAME - A thin film transistor includes: a silicon nanowire on a substrate, the silicon nanowire having a central portion and both side portions of the central portion; a gate electrode on the central portion; and a source electrode and a drain electrode spaced apart from the source electrode on the both side portions, the source electrode and the drain electrode electrically connected to the silicon nanowire, respectively. | 09-05-2013 |
Patent application number | Description | Published |
20110118127 | MARKER GENES FOR SCREENING OF DRUG-INDUCED TOXICITY IN HUMAN CELLS AND SCREENING METHOD USING THE SAME - The present invention relates to a marker gene for screening a drug inducing toxicity in human and a screening method using the same. More precisely, the invention relates to a microarray on which marker genes up-or down-regulated specifically by 16 drugs inducing pulmonary toxicity, teratogenicity, nephrotoxicity, cardiotoxicity or mutation (Methotrexate, Nitrofurantoin, Amiodarone, Carbamazepine, Valproic acid, Thalidomide, Cisplatin, Gentamycin, Amphotericine, Furylfuramide, N-nitroso-N-methylurea, methylmethanesulfonate, 4-nitroquinoline-N-oxide, 2-nitrofluorene, Doxorubicin and Daunorubicin) are integrated, a kit comprising the said microarray, and a screening method of a drug inducing toxicity in human using the same. The DNA microarray containing the marker gene of the present invention facilitates the construction of Toxtarget Array for screening a drug inducing toxicity in human using drug-specific genes, suggesting that this chip can be effectively used for monitoring drugs or chemicals carrying toxicity to human or determining risks thereof and also it can be used as a tool for examining mechanisms of toxicity/side effects caused by the drugs. | 05-19-2011 |