Casale
Anthony Casale, Wauconda, IL US
Patent application number | Description | Published |
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20090050222 | Three-way poppet valve with intermediate pilot port - An integrated three-way poppet valve is disclosed with an intermediate pilot port and an integral load holding check valve. The valve incorporates a reverse flow check poppet for load hold capability, which enables a lower cost solution compared to a combination of valves of similar functionality. A control method is also disclosed using an integrated three-way poppet valve to control the flow of hydraulic oil to a cylinder, hydraulic motor, or other hydraulic device in proportion to the amount of a current applied to a solenoid coil. Depending on the current applied, the valve blocks all flow or else permits flow from one inlet port to two outlet ports proportional to the current applied. | 02-26-2009 |
20110139260 | Proportional Motion Control Valve - A proportional motion control valve includes an electro-mechanical actuator that provides an infinitely controlled pressure setting in response to an electric signal applied to the electro-mechanical actuator. In another aspect, a proportional motion control valve includes a pilot-operated valve disposed intermediately with respect to a cage and a valve body to fluidly isolate an internal cavity of the valve body from a bore of the cage. The pilot-operated valve is subjected to a hydraulic opening force of pilot fluid that is present in the bore of the cage. A spring is disposed within the internal cavity of the valve body and arranged to subject the pilot-operated valve to a closing spring force. | 06-16-2011 |
20140299197 | METHOD OF CONTROLLING PROPORTIONAL MOTION CONTROL VALVE - A proportional motion control valve includes an electro-mechanical actuator that provides an infinitely controlled pressure setting in response to an electric signal applied to the electro-mechanical actuator. In another aspect, a proportional motion control valve includes a pilot-operated valve disposed intermediately with respect to a cage and a valve body to fluidly isolate an internal cavity of the valve body from a bore of the cage. The pilot-operated valve is subjected to a hydraulic opening force of pilot fluid that is present in the bore of the cage. A spring is disposed within the internal cavity of the valve body and arranged to subject the pilot-operated valve to a closing spring force. | 10-09-2014 |
Anthony J. Casale, Wauconda, IL US
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20130069423 | HYDRAULIC POWERED PARK BRAKE SYSTEM - A hydraulic circuit for a motor vehicle supports operation of a power steering gear and a power assisted park brake unit incorporating a spring actuated hydraulic release (SAHR) chamber. The hydraulic circuit includes a pump with the power steering gear being connected to receive hydraulic fluid under pressure from the pump. Hydraulic fluid from the pump is delivered to first and second valves, the first or release control valve being connected to the SAHR chamber and the second or recirculation valve being coupled to return hydraulic fluid to a pump inlet. | 03-21-2013 |
Arturo Guillermo Casale, Buenos Aires AR
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20100035350 | DEVICE AND METHOD FOR LABELING AND MEASURING THE RADIOCHEMICAL PURITY OF RADIO-DRUGS - The present invention relates to a device for labeling and measuring the radio-chemical purity of a radio-drug product. There is a microprocessor ( | 02-11-2010 |
Carlo Casale, Busto Arsizio IT
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20100295766 | WHITE BACKLIGHT FOR A DISPLAY - A display backlight is described which produces white light of a specified color point and from light sources of different chromaticities and in which the red wavelengths emitted by the light sources are emitted by light sources of two or more chromaticities from the group of at least three different chromaticities and arranged to be driven with the result that visible, red-colored artifacts are reduced at boundaries of high image contrast when the backlight is coupled to further display components and used for display of a grey scale image. The invention allows production of a display with an adjustable white color point but which also does not suffer from distracting red, fringe-like artefacts reported by users of displays comprising white backlights produced from red, green and blue light sources. A display incorporating the backlight is also described. | 11-25-2010 |
Celso Luis Casale, Sao Carlos BR
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20150217242 | TOTALLY SCREWED STAGGERED ROTOR BARS FOR FEED AND INDUSTRIAL MIXER - This patent application is related to a TOTALLY SCREWED STAGGERED ROTOR BARS FOR FEED AND INDUSTRIAL MIXER, used in the cattle raising sector, more specifically in animal husbandry for meat production, consisting of a rotor divided into three segments staggered at 40° to each other, and each one having three pairs of arms ( | 08-06-2015 |
Charles H. Casale, San Jose, CA US
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20080250377 | CONDUCTIVE DOME PROBES FOR MEASURING SYSTEM LEVEL MULTI-GHZ SIGNALS - Methods and apparatus for accessing a high speed signal routed on a conductive trace on an internal layer of a printed circuit board (PCB) using high density interconnect (HDI technology) are provided. The conductive trace may be coupled to a microvia (μVia) having a conductive dome disposed above the outer layer pad of the μVia. In-circuit test (ICT) fixtures or high speed test probes may interface with the conductive dome to test the high speed signal with decreased reflection loss and other parasitic effects when compared to conventional test points utilizing plated through-hole (PTH) technology. | 10-09-2008 |
Cristiano Casale, Spilamberto(mo) IT
Patent application number | Description | Published |
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20090039084 | Opening Device for a Sealed Package Containing a Pourable Food Product - An opening device for a sealed package containing a pourable food product and having at least one removable portion includes a frame defining a pour opening and having a fastening portion fixable to the package about the removable portion. A cap is adapted to be fitted to the frame to close the pour opening and is removable from the pour opening to permit pour-out of the food product. An anchoring portion which engages the pour opening is fixable directly to the removable portion, and is removable from the pour opening to at least partly detach the removable portion from the package. The anchoring portion is connected integrally to the frame by a breakable connecting mechanism, and is connected to the cap so as to move together with the cap when removing the cap from the pour opening. | 02-12-2009 |
Cristiano Casale, Spilamberto (modena) IT
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20100264146 | RECLOSABLE OPENING DEVICE FOR PACKAGES OF POURABLE FOOD PRODUCTS - A reclosable opening device for a sealed package of a pourable food product includes a frame fitted about a pierceable portion of the package and defining a through pour opening; a removable threaded cap that screws onto the frame to close the pour opening; a tubular cutter engaging the pour opening and having a cutting device which cooperates with the pierceable portion to unseal the package; a first connector connecting the cap to the cutter, and which, as the cap is unscrewed, pushes the cutter towards the pierceable portion and a second connector connecting the frame to the cutter, and which, in use, feed the cutter along a predetermined piercing path through the pierceable portion in response to unscrewing of the cap; and the piercing path, as the cap is unscrewed, has a first portion of pure axial translation, followed by a second portion of both axial and rotary motion. | 10-21-2010 |
20140230379 | METHOD OF OPENING A PACKAGE OF POURABLE FOOD PRODUCT - A reclosable opening device for a sealed package of a pourable food product includes a frame fitted about a pierceable portion of the package and defining a through pour opening; a removable threaded cap that screws onto the frame to close the pour opening; a tubular cutter engaging the pour opening and having a cutting device which cooperates with the pierceable portion to unseal the package; a first connector connecting the cap to the cutter, and which, as the cap is unscrewed, pushes the cutter towards the pierceable portion and a second connector connecting the frame to the cutter, and which, in use, feed the cutter along a predetermined piercing path through the pierceable portion in response to unscrewing of the cap; and the piercing path, as the cap is unscrewed, has a first portion of pure axial translation, followed by a second portion of both axial and rotary motion. | 08-21-2014 |
Cristiano Casale, Modena IT
Patent application number | Description | Published |
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20090308833 | OPENING DEVICE, SCREW CAP FOR USE IN SUCH AN OPENING DEVICE AND METHOD OF FORMING SUCH AN OPENING DEVICE - An opening device for a packaging container comprises a neck portion and a screw cap. The opening device comprises a wall of the first part of the screw cap being with a weakening extending in a circumferential direction of the first part and a recess extending in a longitudinal centre axis direction of the first part. The recess is arranged to receive a projection of the neck portion, which projection is directly injection-moulded in the recess. A tamper flap of the first part, which tamper flap is defined by the weakening and the recess, is automatically deformable in connection with a first time opening of the packaging container by cap rotation. | 12-17-2009 |
Cristiano Casale, Spilamberto IT
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20120138634 | SHEET PACKAGING MATERIAL FOR PRODUCING SEALED PACKAGES OF POURABLE FOOD PRODUCTS - A sheet packaging material for producing a sealed package of a pourable food product comprises one base layer, a number of lamination layers covering both sides of the base layer, and a removable portion which, in use, can be detached partly from the rest of the packaging material along at least one arc-shaped cutting line and folded at a folding zone extending between opposite ends of the cutting line to free a pour opening; the removable portion comprises a central area made of whole packaging material and which, in use, remains attached to the rest of the packaging material through a permanent bridge defined by the folding zone, and a peripheral area for cutting interaction, extending around part of the central area, containing the cutting line and including at least one pre-laminated opening formed by a through slot at least in the base layer and covered by one or more of the lamination layers. | 06-07-2012 |
David M. Casale, Pennsauken, NJ US
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20140265042 | 3D Direct Write Patterning Apparatus and Method of Generating Patterns on Doubly-Curved Surfaces - Disclosed is a system and method for patterning internal and/or external doubly-curved surfaces by use of a light source, three-dimensional scanning optics, computer controller, and a multi-axis robot. The system is capable of digitally receiving shape, location, and pattern data of a three-dimensional doubly-curved surface and applying said pattern over large areas with high precision in a seamless fashion. | 09-18-2014 |
Elena Casale, Somma Lombardo (va) IT
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20110294790 | BICYCLIC PYRAZOLE AND ISOXAZOLE DERIVATIVES AS ANTITUMOR AND ANTINEURODEGENERATIVE AGENTS - Bicyclic pyrazole and isoxazole derivatives of formula (I) and pharmaceutically acceptable salts thereof, as defined in the specification, process for their preparation and pharmaceutical compositions comprising them are disclosed; the compounds of the invention may be useful in therapy in the treatment of diseases mediated by HSP90 protein, like cancer and neurodegenerative disorders. | 12-01-2011 |
20120046266 | RESORCINOL DERIVATIVES AS HSP90 INHIBITORS - The present invention relates to substituted resorcinol derivatives which inhibit the activity of Heat Shock Protein HSP90. The compounds of the invention are therefore useful in treating proliferative diseases such as cancer and neurodegenerative diseases. The present invention also provides processes for preparing these compounds, pharmaceutical compositions comprising them, methods of treating diseases and the pharmaceutical compositions comprising these compounds. | 02-23-2012 |
20120184546 | [1,2,4]TRIAZOLO [1,5-C]PYRIMIDINE DERIVATIVES AS HSP90 MODULATORS - The present invention relates to [1,2,4]triazolo[1,5-c]pyrimidine derivatives of formula (I) which inhibit the activity of Heat Shock Protein Hsp90. The compounds of the invention are therefore useful in treating proliferative diseases such as cancer and neurodegenerative diseases. The present invention also provides processes for preparing these compounds, methods of treating diseases and the pharmaceutical compositions comprising these compounds. | 07-19-2012 |
20120245143 | 3-0X0-2,3-DIHYDRO-1H-ISOINDOLE-4-CARBOXAMIDES WITH SELECTIVE PARP-1 INHIBITION - There are provided substituted 3-oxo-2,3-dihydro-1H-isoindole-4-carboxamide derivatives (I) which selectively inhibit the activity of poly (ADP-ribose) polymerase PARP-1 with respect to poly (ADP-ribose) polymerase PARP-2. The compounds of this invention are therefore useful in treating diseases such as cancer, cardiovascular diseases, central nervous system injury and different forms of inflammation. The present invention also provides methods for preparing these compounds, pharmaceutical compositions comprising these compounds, and methods of treating diseases utilizing pharmaceutical compositions comprising these compounds. | 09-27-2012 |
20140045836 | [1,2,4]TRIAZOLO[1,5-C]PYRIMIDINE DERIVATIVES AS HSP90 MODULATORS - The present invention relates to [1,2,4]triazolo[1,5-c]pyrimidine derivatives which inhibit the activity of Heat Shock Protein Hsp90. The compounds of the invention are therefore useful in treating proliferative diseases such as cancer and neurodegenerative diseases. The present invention also provides processes for preparing these compounds, methods of treating diseases and the pharmaceutical compositions comprising these compounds. | 02-13-2014 |
20140243347 | SUBSTITUTED 3,4-DIHYDROPYRROLO[1,2-a]PYRAZIN-1(2H)-ONE DERIVATIVES AS KINASES INHIBITORS - The present invention relates to substituted 3,4-dihydropyrrolo[1,2-a]pyrazin-1(2H)-one derivatives which modulate the activity of protein kinases and are therefore useful in treating diseases caused by dysregulated protein kinase activity. The present invention also provides methods for preparing these compounds, pharmaceutical compositions comprising these compounds, and methods of treating diseases utilizing such compounds or the pharmaceutical compositions containing them. | 08-28-2014 |
Ettore Casale, Quartu Sant'Elena (ca) IT
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20140343575 | Device For Tissues Sampling And Grafting - A device for tissue sampling and grafting has a handle (2), to whose end is fixed a coupling (4), a needle (6) fixed to the coupling. The device also includes a piston (3) connected to a pin (7). The piston and pin translate between an external condition (A), wherein a tip (73) of the in protrudes beyond the needle, and an internal condition (B), wherein the tip is retracted inside the needle. The device also includes a tip (5), having a truncated free end (51) that can be sharpened, constrained in a roto-translating way to the coupling, placed co-axially and externally to the needle and moved between a retracted condition (C) and an advanced condition. | 11-20-2014 |
Ettore Casale, Quartu Sant'Elena IT
Patent application number | Description | Published |
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20140343575 | Device For Tissues Sampling And Grafting - A device for tissue sampling and grafting has a handle (2), to whose end is fixed a coupling (4), a needle (6) fixed to the coupling. The device also includes a piston (3) connected to a pin (7). The piston and pin translate between an external condition (A), wherein a tip (73) of the in protrudes beyond the needle, and an internal condition (B), wherein the tip is retracted inside the needle. The device also includes a tip (5), having a truncated free end (51) that can be sharpened, constrained in a roto-translating way to the coupling, placed co-axially and externally to the needle and moved between a retracted condition (C) and an advanced condition. | 11-20-2014 |
Frank Casale, Fishers, IN US
Patent application number | Description | Published |
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20140116572 | VEHICLE FLUID EXCHANGE WITH TELEMETRY DATA TRANSFER - The present invention is a fluid exchange machine, such as a brake fluid exchange machine or an automatic transmission fluid exchange machine, that includes a new fluid tank, a waste fluid collector, a pump for introducing new fluid into a vehicle, and a controller for managing the operation of the fluid exchange machine. Coupled to the controller is a global positioning satellite (GPS) receiver that can identify the location of the fluid exchange machine at all times, and a wireless transmitter that can wirelessly transmit the location of the fluid exchange machine to a remote location. In a preferred embodiment, the wireless transmitter can also track and communicate the number and time of each fluid exchange operation, and the amount of fluid, so the recipient of the data can discern where the fluid exchange machine is at all times, how many fluid exchange operations the machine performs, and when each fluid exchange operation is performed. | 05-01-2014 |
20160023640 | WIRELESS, VOICE ACTIVATED FLUID EXCHANGE MACHINE - The present invention is directed to a fluid exchange machine for replacing fluid in a vehicle subsystem that can be controlled remotely using wireless technology to make fluid exchange operations easier, safer, and more convenient. The fluid exchange machine of the present invention operates within a number of different platforms and communication technologies to provide a wide array of options. Using smartphones, tablets, or other hand held devices, a technician can send instructions wirelessly to the machine to both operate the machine and retrieve important data from the machine. The communication in one preferred embodiment uses voice commands to instruct and control the machine, while other embodiments utilize more traditional data input can be utilized. | 01-28-2016 |
Giuliano Casale, Belfast GB
Patent application number | Description | Published |
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20110093253 | ESTIMATING SERVICE RESOURCE CONSUMPTION BASED ON RESPONSE TIME - Implementations of the present disclosure provide computer-implemented methods including defining a workload comprising a plurality of service requests, each service request corresponding to a class of a plurality of classes, applying the workload to a computer system that receives and processes service requests, measuring a response time of the computer system for each request of the workload, estimating a mean service demand for each class based on the response times and a base queuing model that represents the computer system, and generating the queuing model based on the mean service demands and characteristics of the workload. | 04-21-2011 |
Giuliano Casale, Pavia IT
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20120239376 | PREDICTING PERFORMANCE OF A CONSOLIDATED VIRTUALIZED COMPUTING ENVIRONMENT - Implementations of the present disclosure provide computer-implemented methods for predicting a performance of a consolidated virtualized computing environment. Methods include processing benchmark workloads using a plurality of virtual machines to generate a plurality of traces, each trace including data corresponding to requests issued by a respective virtual machine operating in an isolated environment, storing the plurality of traces in one or more trace repositories, each trace repository provided as a computer-readable storage medium, selecting a trace from the plurality of traces stored in the one or more trace repositories, parameterizing a queuing model based on the trace, the queuing model representing request queuing in the consolidated virtualized computing environment, and processing the queuing model using one or more processors to generate one or more response time estimates for the consolidated virtualized computing environment. | 09-20-2012 |
20130007259 | Characterizing Web Workloads For Quality of Service Prediction - Implementations of the present disclosure provide systems and methods directed to receiving, at a computing device, trace data provided in a trace log file corresponding to a server, parameterizing, using the computing device, a first Markovian Arrival Process (MAP) model based on the trace data, parameterizing, using the computing device, a second MAP model based on the trace data, defining a queuing model that models a performance of the server and that includes the first MAP model and the second MAP model, and storing the queuing model in computer-readable memory. | 01-03-2013 |
20130346436 | Simulation Techniques for Predicting In-Memory Database Systems Performance - Methods for performance evaluation of admission control policies (ACPs) include storing a simulation model including an admission queue and a finite capacity region (FCR), the admission queue admitting queries to the FCR based on an active ACP, the FCR modeling a resource constraint, generating traces, each trace being generated based on processing a single query using the database system, the single query being associated with a query type of a plurality of query types, for each query type, determining a query fork size and a service time from an associated trace to provide a plurality of tuples, each tuple being associated with a query type and including the fork size and the service time associated with the query type, parameterizing the simulation model based on the plurality of tuples, and for each of the ACPs, generating a performance parameter by applying a workload to the simulation model. | 12-26-2013 |
Joseph N. Casale, Cary, NC US
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20100140499 | Self-Powered Sanitizing Door Handle - The present application is directed to methods and devices for a self-powered sterilizing door handle. The door handle consists of an actuator pivotably attached to a housing. The housing is attached to a door and contains a gear train and a generator. Movement of the actuator rotates the gear train which in turns activates the generator. The generator produces electrical energy that powers a UV light source. The UV light produced by the UV light source is directed to an outer surface of the actuator, thereby deactivating microorganisms on the outer surface. | 06-10-2010 |
Luca Casale, Venaria Torino IT
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20080209258 | Disaster Recovery Architecture - A method and system for disaster recovery in a packet-based network. The network includes a production site and a recovery site coupled together by the packet-based network. Mirroring software on the production site keeps a recovery site up to date to the last transaction occurring on the production site. A recovery control server polls the production site in order to detect a disaster condition or other failure. Upon detection of a problem at the production site, the recovery control server reconfigures the network so those attempts to access the production site are routed to the recovery site. | 08-28-2008 |
Malcolm Casale, Mission Viejo, CA US
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20160101098 | SMALL MOLECULE ACTIVATORS OF NRF2 PATHWAY - This disclosure relates to compounds that act as activators of the NRF2/KEAP1/ARE pathway. Specifically, the compounds provided herein can act as high affinity reversible bindings for the NRF2 inhibitor, KEAP1. In some cases, NRF2/KEAP1/ARE pathway activation compounds are capable of repressing expression of inflammatory markers and/or reducing levels of TNFa to provide neuroprotective anti-inflammatory effects in the CNS. Such compounds are useful in the treatment of a variety of diseases including Huntington's disease, Parkinson's disease, Alzheimer's disease, inflammation, and cancer. | 04-14-2016 |
Manuele Casale, Rome IT
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20090221927 | APPARATUS AND METHOD FOR VIDEORHINOHYGROMETRIC (VRI) MEASURES - A videorhinohygrometric measuring apparatus ( | 09-03-2009 |
Michael Casale, Hockessin, DE US
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20110233299 | Low Noise Back Pressure Regulator for Supercritical Fluid Chromatography - A drive mechanism for back pressure regulator used in liquid chromatography, supercritical fluid chromatography, or supercritical fluid extraction allows very fine automated control over a very wide range of pressures by combining a linear actuator compressing a spring, pushing a pin. The nozzle assembly of the regulator comprises a flow through chamber containing a diaphragm and a seat, in which the pin pushes the diaphragm against the seat, together with an upstream pressure sensor and electronic feedback control to the motor of the actuator. The BPR of the embodiments exhibits high pressure stability and extremely low pressure noise, even at moderate to high pressures. The exemplary BPR can be use at either constant pressure or to generate pressure programs where the pressure is varied versus time. Further, the nozzle assembly has a field-replaceable head, requiring no mechanical adjustment on replacement. | 09-29-2011 |
20130192698 | LOW NOISE BACK PRESSURE REGULATOR FOR SUPERCRITICAL FLUID CHROMATOGRAPHY - A drive mechanism for back pressure regulator used in liquid chromatography, supercritical fluid chromatography, or supercritical fluid extraction allows very fine automated control over a very wide range of pressures by combining a linear actuator compressing a spring, pushing a pin. The nozzle assembly of the regulator comprises a flow through chamber containing a diaphragm and a seat, in which the pin pushes the diaphragm against the seat, together with an upstream pressure sensor and electronic feedback control to the motor of the actuator. The BPR of the embodiments exhibits high pressure stability and extremely low pressure noise, even at moderate to high pressures. The exemplary BPR can be use at either constant pressure or to generate pressure programs where the pressure is varied versus time. Further, the nozzle assembly has a field-replaceable head, requiring no mechanical adjustment on replacement. | 08-01-2013 |
Michael A. Casale, Hockessin, DE US
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20100040483 | Compressible fluid pumping system - An invention is claimed that enables the pumping of compressible fluids at high pressures when an accurate flow is desired. Two pressure sources, for example pumps plumbed in series, separate thermodynamic work, such as pressurization, at the first pressure source from a volumetric or matter metering function in the second pressure source. One example is a flowstream delivery for a chemical instrumentation system that is manufactured from relatively unsophisticated pumps yet delivers precise flows with low pulsation (<1 %) over pressures greater than 100 bar. An advantage of one embodiment allows the economical conversion of typical HPLC systems to state of-the-art supercritical fluid chromatography (SFC) systems with minimal modification to system components. | 02-18-2010 |
Nicholas J. Casale, Horsham, PA US
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20110086098 | RAPIDLY DISINTEGRATING GELATINOUS COATED TABLETS - The present invention relates to an improved gelatinous coated dosage form having two end regions coated with gelatinous materials and an exposed circumferential band. Openings are provided in at least the exposed band to reveal the core material. The invention also relates to methods for manufacturing such gelatinous coated dosage forms. | 04-14-2011 |
20140328913 | RAPIDLY DISINTEGRATING GELATINOUS COATED TABLETS - The present invention relates to an improved gelatinous coated dosage form having two end regions coated with gelatinous materials and an exposed circumferential band. Openings are provided in at least the exposed band to reveal the core material. The invention also relates to methods for manufacturing such gelatinous coated dosage forms. | 11-06-2014 |
20160051479 | RAPIDLY DISINTEGRATING GELATINOUS COATED TABLETS - The present invention relates to an improved gelatinous coated dosage form having two end regions coated with gelatinous materials and an exposed circumferential band. Openings are provided in at least the exposed band to reveal the core material. The invention also relates to methods for manufacturing such gelatinous coated dosage forms. | 02-25-2016 |
Ralph Casale, Westford, MA US
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20100292313 | COMPOSITIONS AND METHODS FOR TREATING ISCHEMIA AND ISCHEMIA-REPERFUSION INJURY - The present invention relates to compositions comprising a substantially pure compound represented by Structural Formula II: | 11-18-2010 |
20110160294 | COMPOSITIONS AND METHODS FOR TREATING ISCHEMIA AND ISCHEMIA-REPERFUSION INJURY - The present invention relates to compositions comprising a substantially pure compound represented by Structural Formula I: | 06-30-2011 |
20120135932 | Compositions And Methods For Treating Ischemia And Ischemia-Reperfusion Injury - The present invention relates, in some embodiments, to compositions comprising a substantially pure compound represented by Structural Formula (I) and methods of using such compounds to activate cytoprotective kinases. In additional embodiments, the invention relates to methods for treating an ischemia or an ischemia-reperfusion injury in a subject, comprising administering to the subject an effective amount of a compound of the invention (e.g., in multiple doses). The values and preferred values of the variables in Structural Formula (I) are defined herein. | 05-31-2012 |
20130237483 | Lipoyl Compounds And Their Use for Treating Ischemic Injury - The present invention relates, in various embodiments, to a compound represented by Structural Formula (I), pharmaceutically acceptable salts or prodrugs thereof, and compositions comprising said compounds, or pharmaceutically acceptable salts or prodrugs thereof. Methods of using compounds of Structural Formulas (I) and (la) or compositions comprising compounds of Structural Formulas (I) and (la), or pharmaceutically acceptable salts or prodrugs thereof, to treat ischemia or ischemia-reperfusion injury are also disclosed. | 09-12-2013 |
20140274917 | Compositions and Methods for Treating Ischemia and Ischemia-Reperfusion Injury - The present invention relates to compositions comprising a substantially pure compound represented by Structural Formula I: | 09-18-2014 |
20150065564 | LIPOYL COMPOUNDS AND METHODS FOR TREATING ISCHEMIC INJURY - The present invention relates, in various embodiments, to a compound represented by Structural Formula (I), pharmaceutically acceptable salts or prodrugs thereof, and compositions comprising said compounds, or pharmaceutically acceptable salts or prodrugs thereof. Methods of using compounds of Structural Formulas (I) and (Ia) or compositions comprising compounds of Structural Formulas (I) and (Ia), or pharmaceutically acceptable salts or prodrugs thereof, to treat ischemia or ischemia-reperfusion injury are also disclosed. | 03-05-2015 |
20150329519 | Formulations Comprising Lipoyl Compounds - Provided herein are aqueous pharmaceutical formulations comprising monomeric lipoyl compounds, such as compounds of Structural Formula I: | 11-19-2015 |
Ralph A. Casale, Westford, MA US
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20100190660 | Methods, Compositions And Libraries Pertaining To PNA Dimer And PNA Oligomer Synthesis - This invention pertains to the field of PNA dimer and PNA oligomer synthesis. | 07-29-2010 |