Patent application number | Description | Published |
20080253930 | CODED TUBES AND CONNECTORS FOR MICROFLUIDIC DEVICES - Tubes and connectors for microfluidic devices are described. The tubes are provided with a coding on their external surface for example, to allow easier identification. The connector comprises a plurality of through holes going through the connector. Each through hole can accommodate a pin for connection of microfluidic device ports on one side of the pin and connection of a reagent or sample liquid tube on the other side of the pin. | 10-16-2008 |
20100186840 | MULTI-VALVE MICROFLUIDIC DEVICES AND METHODS - Multi-valve autoregulatory microfluidic devices and methods are described. The described devices and methods offer improved performance and new means of tuning autoregulatory effects in microfluidic devices. | 07-29-2010 |
20100267064 | METHODS FOR QUANTITATIVE TARGET DETECTION AND RELATED DEVICES AND SYSTEMS - Described herein is a method for detection of a target in a sample and related devices and systems. | 10-21-2010 |
20100267162 | METHODS FOR QUANTITATIVE TARGET DETECTION AND RELATED DEVICES AND SYSTEMS - Described herein are methods for quantitative target detection in a sample through use of microbeads and related devices and systems. | 10-21-2010 |
20110177518 | METHODS AND DEVICES FOR MICRO-ISOLATION, EXTRACTION, AND/OR ANALYSIS OF MICROSCALE COMPONENTS - Provided herein are devices and methods for the micro-isolation of biological cellular material. A micro-isolation apparatus described can comprise a photomask that protects regions of interest against DNA-destroying illumination. The micro-isolation apparatus can further comprise photosensitive material defining access wells following illumination and subsequent developing of the photosensitive material. The micro-isolation apparatus can further comprise a chambered microfluidic device comprising channels providing access to wells defined in photosensitive material. The micro-isolation apparatus can comprise a chambered microfluidic device without access wells defined in photosensitive material where valves control the flow of gases or liquids through the channels of the microfluidic device. Also included are methods for selectively isolating cellular material using the apparatuses described herein, as are methods for biochemical analysis of individual regions of interest of cellular material using the devices described herein. Further included are methods of making masking arrays useful for the methods described herein. | 07-21-2011 |
20110275544 | MICROFLUIDIC INTEGRATION WITH NANOSENSOR PLATFORM - The present invention describes microfluidics being employed to achieve multiplex surface functionalization of nanosensor chips by selectively delivering probe molecules to individual nanosensors in an array, and microfluidics being employed to achieve delivery of a solution containing multiple analytes over individual nanosensors in an array, where each nanosensor was previously configured with a specific capture molecule. | 11-10-2011 |
20110287959 | PAN-ANTIBODY ASSAYS - PRINCIPLES, METHODS, AND DEVICES - The present invention includes methods, assays, and devices for assaying a sample to detect the presence, absence, or level of at least one analyte in a biological sample using a pan-antibody panel or multiplexed immunoassay, wherein at least one analyte is detected by two or more antibodies. Certain embodiments include the use of a microfluidic device in the immunoassay. Further embodiments of the invention include assays, methods, and devices to detect the presence, absence, or level of at least one analyte which is determined for a diagnostic or a scientific purpose. Still further embodiments of the invention include assays, methods, and devices to detect the presence, absence, or level of at least one analyte which is indicative of a condition or disease. Yet further embodiments of the invention include incorporating additional diagnostic techniques (e.g., PCR, RT-PCR, and DNA hybridization arrays) to the assays, device, and methods. | 11-24-2011 |
20120085648 | MICROFLUIDIC FLUID SEPARATOR AND RELATED METHODS - A microfluidic fluid separator for separating target components of a fluid by filtration is described. Methods for separating target components of a fluid by filtration and methods for processing blood on a large scale with the microfluidic fluid separator are provided. | 04-12-2012 |
20130210646 | HEMOMOSAIC: HIGH-THROUGHPUT TECHNIQUE FOR RARE CELL DETECTION IN LIQUID SAMPLES BY MASSIVELY MULTIPLEXED PCR IN A PHOTOLITHOGRAPHIC MATRIX - Described microfluidic technology focused on: 1) direct integration of microfluidic devices with solidified liquid tissue samples, 2) subordination of architectural and operational principles of microfluidic devices specific tissue structure and needs and/or 3) on-chip sample acquisition integrated with the detection measurement within the same device. In contrast to conventional methods of off-chip sample prep and subsequent insertion into a detection device, new applications are possible on solidified liquid or solid tissue samples, such as in situ PCR. | 08-15-2013 |
20130267005 | MICROFLUIDIC FLUID SEPARATOR AND RELATED METHODS - A microfluidic fluid separator for separating target components of a fluid by filtration is described. Methods for separating target components of a fluid by filtration and methods for processing blood on a large scale with the microfluidic fluid separator are provided. | 10-10-2013 |