Valeria
Valeria Acquarone, Hackettstown, NJ US
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20100129521 | Heat Processed Products Having Altered Monomer Profiles and Processes For Controlling The Epimerization of (-)-Epicatechin and (+)-Catechin In The Products - A method for controlling the epimerization of (−)-epicatechin to (−)-catechin in an epicatechin-containing product, preferably an edible product, or of (+)-catechin to (+)-epicatechin in a catechin-containing product, comprises the step of heating the product at a temperature of up to about 200° C. and at a pH of up to about 8. Under either method, the epimerization may be carried out in an open food processor in a reduced oxygen atmosphere or in a closed food processor. The edible product may be pasteurized, boiled, or sterilized during the epimerization. Epimerization is minimized by lowering the heating temperature, by lowering the pH, and/or by lowering the heating time. Conversely, the epimerization is maximized by increasing the heating temperature, by increasing the pH, and/or by increasing the heating time. The edible product may contain or be a fruit product, a vegetable product, a cereal product, a bean product, a nut product, a spice product, or a botanical product. | 05-27-2010 |
Valeria Alasino, Cordoba AR
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20130195924 | WATER-SOLUBLE PHARMACEUTICAL COMPOSITION COMPRISING AT LEAST ONE THERAPEUTICALLY ACTIVE SUBSTANCE HAVING HYDROPHOBIC PROPERTIES AND AT LEAST ONE COMPOUND SELECTED FROM AMONG SIALOGLYCOSPHINGOLIPIDS, GLYCOSPHINGOLIPIDS OR A MIXTURE OF SIALOGLYCOSPHINGOLIPIDS AND GLYCOSPHINGOLIPIDS - This invention discloses water soluble pharmaceutical compositions including at least one therapeutically active substance and at least one compound selected from the sialoglycosphingolipids, the glycosphingolipids or a mixture of sialoglicosphingolipids and glycosphingolipids, in which at least one of the therapeutically active substances is a drug with hydrophobic characteristics. In particular, sterile compositions for i.v. administration, composed of nano-glycosphingolipids micelles or modified glycosphingolipids, which can be coated with albumin in a noncovalent form and which allow transport and controlled release of highly hydrophobic molecules are disclosed. | 08-01-2013 |
Valeria Animobono, Fabriano IT
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20110062952 | METHOD FOR ESTIMATING THE WEIGHT OF THE CONTENTS OF A HOUSEHOLD APPLIANCE - A method for estimating the value of the weight of the contents of the oscillating assembly of an electronically controlled household appliance is provided. The oscillating assembly is connected to a frame by a suspension system having a damper. The damper includes at least two mechanical elements adapted to move reciprocally, a magnetic element which detects reciprocal motion, depending upon the distance between the two elements, the magnetic sensor generates an electrical signal. A reading of an initial value of an electric parameter, is taken when the oscillating assembly is empty. A mathematical function is identified on the basis of the initial value and of a plurality of predetermined parameters, which relate the electrical parameter to the weight of the contents. A second reading is taken when contents have been loaded in, and the value of the weight of the contents is estimated by using the mathematical function and electric parameters. | 03-17-2011 |
Valeria Barbarito, Roma IT
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20150356742 | COMPUTER IMPLEMENTED METHODS FOR IDENTIFYING CHANNELS IN A 3D VOLUME AND COMPUTER PROGRAM PRODUCT IMPLEMENTING THE METHODS - The methods comprise: | 12-10-2015 |
Valeria Becker, Buenos Aires AR
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20100318957 | SYSTEM, METHOD, AND APPARATUS FOR EXTENSIBLE BUSINESS TRANSFORMATION USING A COMPONENT-BASED BUSINESS MODEL - A computer-implemented method for operating a business including operations to receive an enterprise model, define at least one new association between a first and a second business element in the enterprise model, federate a business analysis tool, and determine a business-related impact of the new association on other business elements in the enterprise model. The enterprise model is received at a model server and includes two or more business elements and a map of business components. The collection of business elements indicates associations between one or more business elements. The business analysis tools can filter the enterprise model and are federated by incorporating a business element generated from the business analysis tool into the enterprise model. The business-related impact is determined by using the business analysis tool. | 12-16-2010 |
Valeria Bertacco, Ann Arbor, MI US
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20080295043 | Automatic Error Diagnosis and Correction for RTL Designs - A computer executable tool facilitates integrated circuit design and debugging by working directly at the Register Transfer Level, where most design activities take place. The tool determines when an integrated circuit design produces incorrect output responses for a given set of input vectors. The tool accesses the expected responses and returns the signal paths in the integrated circuit that are responsible for the errors along with suggested changes for fixing the errors. The tool may operate at the RTL, which is above the gate-level abstraction which means that the design errors will be much more readily understood to the designer, and may improve scalability and efficiency. | 11-27-2008 |
20090089615 | FIELD REPAIRABLE LOGIC - A state matcher for a logic circuit may detect at least one of a buggy state of the logic circuit, a precursor to a buggy state of the logic circuit and a verified state of the logic circuit based on a plurality of signal values indicative of a state of the logic circuit. A recovery controller for a microprocessor may reconfigure the microprocessor to a trusted feature mode in response to receiving a signal indicating that the microprocessor is in a predefined state and operate the microprocessor in the trusted feature mode for a predetermined period of time. | 04-02-2009 |
20090138772 | MICROPROCESSOR AND METHOD FOR DETECTING FAULTS THEREIN - A method for detecting microprocessor hardware faults includes sending at least one input signal to a logic block within the microprocessor, collecting an output response to the input signal from the logic block, and determining whether the output response matches an expected output response of the logic block. | 05-28-2009 |
20110087861 | System for High-Efficiency Post-Silicon Verification of a Processor - A post-silicon validation technique is able to craft randomized executable code, with known final outcomes, as a verification test that is executable on a hardware, such as a prototype microprocessor. A verification device is able to generate the test, in the form of programs, in such a way that at the end of the execution, the initial state of the test hardware is restored. Therefore, the final state of such a reversible program is known a priori. The technique may use a program generation algorithm, agnostic to any particular instruction set on the test hardware. In some examples, that algorithm is executed on the test hardware to generate the verification test, which is then executed on that test hardware. In other examples, the verification test is generated on another processor coupled to the test hardware. In either case, the verification test may contain initial and inverse operations determined from the test hardware. | 04-14-2011 |
20110214014 | MICROPROCESSOR AND METHOD FOR DETECTING FAULTS THEREIN - A method for detecting microprocessor hardware faults includes sending at least one input signal to a logic block within the microprocessor, collecting an output response to the input signal from the logic block, and determining whether the output response matches an expected output response of the logic block. | 09-01-2011 |
20110257955 | Gate-Level Logic Simulator Using Multiple Processor Architectures - Techniques for simulating operation of a connectivity level description of an integrated circuit design are provided, for example, to simulate logic elements expressed through a netlist description. The techniques utilize a host processor selectively partitioning and optimizing the descriptions of the integrated circuit design for efficient simulation on a parallel processor, more particularly a SIMD processor. The description may be segmented into cluster groups, for example macro-gates, formed of logic elements, where the cluster groups are sized for parallel simulation on the parallel processor. Simulation may occur in an oblivious as well as event-driven manner, depending on the implementation. | 10-20-2011 |
20120011422 | MICROPROCESSOR AND METHOD FOR DETECTING FAULTS THEREIN - A method for detecting microprocessor hardware faults includes sending at least one input signal to a logic block within the microprocessor, collecting an output response to the input signal from the logic block, and determining whether the output response matches an expected output response of the logic block. | 01-12-2012 |
20150268293 | System and Method for Statistical Post-Silicon Validation - The system and method described herein relate to a bug positioning system for post-silicon validation of a prototype integrated circuit using statistical analysis. Specifically, the bug positioning system samples output and intermediate signals from a prototype chip to generate signatures. Signatures are grouped into passing and failing groups, modeled, and compared to identify patterns of acceptable behavior and unacceptable behavior and locate bugs in space and time. | 09-24-2015 |
Valeria Bottarel, Novara IT
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20120133151 | DEVICE AND RELATIVE METHOD FOR SCAVENGING ENERGY - An energy scavenging device includes an electromagnetic transducer adapted to generate a current in response to accelerations impressed thereto. The device also includes a power switching stage input with the current generated by the electromagnetic transducer, having a network of controlled switches adapted to alternately deliver on output nodes of the switching stage an output current that does not invert its sign and to short-circuit the transducer. There is an output capacitor coupled between the output nodes of the power stage. A controller having a sensor coupled to the electromagnetic transducer is to sense the current flowing therethrough, the controller being adapted to drive the switches of the power stage in order to either short-circuit the electromagnetic transducer or to direct the current flowing through the transducer to charge the output capacitor. | 05-31-2012 |
20120262221 | LOW VOLTAGE ISOLATION SWITCH, IN PARTICULAR FOR A TRANSMISSION CHANNEL FOR ULTRASOUND APPLICATIONS - A low voltage isolation switch is coupled between an input terminal suitable for receiving a high voltage signal and an output terminal suitable for transmitting this high voltage signal to a load. The isolation switch includes a first driving transistor coupled between a first reference terminal and an intermediate node, a second driving transistor coupled between the intermediate node and the second reference terminal, a control transistor connected across a diode block coupled between the input and output terminals. The control transistor has a control terminal connected to the intermediate node through a low voltage decoupling block that includes first and second substrate terminals, first and second parasitic capacitive element connected to these first and second substrate terminals, and first and second decoupling transistors coupled in parallel to each other and having control terminals connected to the first and second parasitic capacitive elements, respectively. | 10-18-2012 |
20120313689 | LOW VOLTAGE ISOLATION SWITCH, IN PARTICULAR FOR A TRANSMISSION CHANNEL FOR ULTRASOUND APPLICATIONS - A low voltage isolation circuit is coupled between an input terminal for receiving a high voltage signal and an output terminal for transmitting the high voltage signal to a load. The isolation circuit includes a driving block; having a first driving transistor coupled between a first voltage reference and an intermediate node and a second driving transistor coupled between the intermediate node and a second voltage reference; an isolation block connected between the input and output terminals and, through a protection block to the intermediate node. The protection block includes first and second protection transistors (MD | 12-13-2012 |
20130265100 | LOW VOLTAGE ISOLATION SWITCH, IN PARTICULAR FOR A TRANSMISSION CHANNEL FOR ULTRASOUND APPLICATIONS - A low voltage isolation switch is suitable for receiving from a connection node a high voltage signal and transmitting said high voltage signal to a load via a connection terminal. The isolation switch includes a driving block connected between first and second voltage reference terminals and including a first driving transistor coupled between the first voltage reference (Vss) and a first driving circuit node and a second driving transistor coupled between the driving circuit node and the second supply voltage reference. The switch comprises an isolation block connected to the connection terminal (pzt), the connection node, and the driving central circuit node and including a voltage limiter block, a diode block and a control transistor. The control transistor is connected across the diode block between the connection node and the connection terminal and has a control terminal connected to the driving central circuit node. | 10-10-2013 |
20140104002 | CIRCUIT AND METHOD FOR ADJUSTING THE ELECTRIC POWER SUPPLY OF AN ENERGY-SCAVENGING SYSTEM - A differentiator generates a time derivative signal from a time-variable signal. A transconductance amplifier generates a biasing control signal as a function of the time derivative signal. A supply network functions to supply the differentiator and transconductance amplifier. The supply network is driven by the biasing control signal output from the transconductance amplifier. With this configuration, speed of operation of the differentiator and transconductance amplifier vary with the supply provided by the supply network, and the supply is modulated as a function of the received time-variable signal. | 04-17-2014 |
20140239917 | ENERGY HARVESTING SYSTEM WITH SELECTIVELY ACTIVATABLE HARVESTING INTERFACE, AND METHOD OF ENERGY HARVESTING - An energy-harvesting system includes a transducer to convert environmental energy into a harvesting electrical signal. A storage element stores electrical energy derived from conversion of the harvested environmental energy. A harvesting interface supplies an electrical charging signal to the storage element. The harvesting interface is selectively connected to the storage element in response to a control signal. The control signal causes the connection when the harvesting electrical signal exceeds a threshold. Conversely, the control signal causes the disconnection when the harvesting electrical signal is less than the threshold. | 08-28-2014 |
20160036583 | SYNCHRONIZATION METHOD, AND CORRESPONDING DEVICE AND INTEGRATED CIRCUIT - The operation of a circuit exhibiting a delay that is subject to a time spread as a function of process, voltage, and temperature variations is synchronized with a sync signal by applying to the sync signal a digital delay, which can add to the delay that is subject to time spread. | 02-04-2016 |
Valeria Caraiani, Thornhill CA
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20140273589 | LATCHING CONNECTOR ASSEMBLY - The subject matter described herein includes an electrical connector assembly comprising a first connector and a second connector. The first connector includes a main body, a locking member, and first engagement members. The locking member includes an indented portion. The second connector is configured to receive the first connector. The second connector includes a main body and a latching member that is slidable with respect to the main body. The latching member includes a biasing member and second engagement members configured to receive the first engagement members. The locking member of the first connector is configured to deflect the biasing member of the second connector when the first connector is inserted into the second connector such that the biasing member engages the indented portion of the locking member thereby retaining the locking member in a locked position and indicating proper mating of the first connector and the second connector. The latching member slides with respect to the main body of the second connector to a latched position until the second engagement members receive the first engagement members for securely mating the first and second connectors. | 09-18-2014 |
Valeria Casavola, Bari IT
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20150290167 | TRIMETHYLANGELICIN AS CFTR CORRECTOR IN BRONCHIAL EPITHELIAL CELLS - The invention relates to the use of 4,6,4′-trimethylangelicin (TMA) and structural analogues thereof to prepare a medicament for the treatment of cystic fibrosis with the primary objective of correcting the defective CFTR in a sub-group of cystic fibrosis patients consisting of patients carrying the F508de1-CFTR mutation. | 10-15-2015 |
Valeria Casuscelli, Napoli(na) IT
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20100296340 | NANOTUBE MEMORY CELL WITH FLOATING GATE BASED ON PASSIVATED NANOPARTICLES AND MANUFACTURING PROCESS THEREOF - A method for manufacturing a nanotube non-volatile memory cell is proposed. The method includes the steps of: forming a source electrode and a drain electrode, forming a nanotube implementing a conduction channel between the source electrode and the drain electrode, forming an insulated floating gate for storing electric charges by passivating conductive nanoparticles with passivation molecules and arranging a disposition of passivated conductive nanoparticles on the nanotube, the conductive nanoparticles being adapted to store the electric charges and being insulated by the passivation molecules from the nanotube, and forming a control gate coupled with the channel. | 11-25-2010 |
Valeria Chiono, Bonassola (la Spezia) IT
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20130165957 | Implantable Prosthetic Devices and Solvent-Casting Methods for Manufacturing Same - Implantable prosthetic devices are provided. Such devices include substantially planar supports such as a mesh for surgical use made of polypropylene, and a porous coating membrane formed on at least one face of said support, said porous membrane being formed in situ on the support by the solvent casting technique. Methods for making such prosthetic devices are also provided. | 06-27-2013 |
Valeria Cinnera Martino, Valverde IT
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20150219693 | INTEGRATED SEMICONDUCTOR DEVICE COMPRISING A HALL EFFECT CURRENT SENSOR - The semiconductor integrated device has a conductive region, for example, an external contact pad, configured to be traversed by a current to be measured. A concentrator of magnetic material partially surrounds the conductive region and has an annular shape open at a point defining an air gap area where a sensitive region is arranged, which is electrically conductive and is typically of doped semiconductor material, such as polycrystalline silicon. The device is integrated in a chip formed by a substrate and by an insulating layer, the sensitive region and the concentrator being formed in the insulating layer. | 08-06-2015 |
Valeria D' Auria, University Of Naples IT
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20100184796 | AGONISTS OF BITTER TASTE RECEPTORS AND USES THEREOF - The present invention relates to agonists of the human bitter-taste receptors hTAS2R46, hTAS2R47 and hTAS2R50 and their role in bitter taste transduction. The invention also relates to methods for identifying molecules that modulate, e.g. suppress, or enhance hTAS2R46, hTAS2R47 and hTAS2R50 bitter taste transduction or bitter taste response. | 07-22-2010 |
Valeria De Paiva, Cupertino, CA US
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20100076957 | METHOD AND APPARATUS FOR DETECTING SENSITIVE CONTENT IN A DOCUMENT - One embodiment of the present invention provides a system that detects sensitive content in a document. In doing so, the system receives a document, identifies a set of terms in the document that are candidate sensitive terms, and generates a combination of terms based on the identified terms that is associated with a semantic meaning. Next, the system performs searches through a corpus based on the combination of terms and determines hit counts returned for each term in the combination and for the combination. The system then determines whether the combination of terms is sensitive based on the hit count for the combination and the hit counts for the individual terms in the combination, and generates a result that indicates portions of the document which contain sensitive combinations. | 03-25-2010 |
Valeria Di Bussolo, Pisa (pi) IT
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20140343001 | INDOLE DERIVATIVES INHIBITORS OF ENZYME LACTATE DEHYDROGENASE (LDH) - The present invention encompasses compounds having general formula (I) able to inhibit the lactate production (lactic acid) involved in the angiogenesis of tumoral tissues, in the glycolytic metabolic process of tumoral cells, of immune system cells in asthmatic diseases, in vascular cells in the pulmonary hypertension, in the treatment of chronic back pain or hyperoxaluria, and in the process by which the parasites protozoan causing malaria obtain most of the necessary energy. | 11-20-2014 |
Valeria Endresz, Szeged HU
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20090252765 | BACILLE CALMETTE-GUERIN (BCG)-BASED ANTI-ATHEROMA VACCINE AND METHODS OF USE THEREOF - The invention relates to a recombinant | 10-08-2009 |
Valeria Fiandra, Giugliano In Campania IT
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20090062574 | Process for the Production of Alpha, Gamma-Dichlorohydrin From Glycerin and Hydrochloric Acid - A process for preparing α,γ-dichlorohydrin starting from glycerin and preferably gaseous anhydrous hydrochloric acid in the presence of low-volatility organic acids as catalysts. | 03-05-2009 |
Valeria GaitÁn, Oslo NO
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20150379882 | METHOD AND APPARATUS FOR MOTION TRACKING DURING SIMULATION OF CLINICAL EMERGENCY SETTINGS - An apparatus for motion tracking during a simulation of a clinical emergency setting includes a camera configured to capture a clinical emergency training area used for the simulation, a wearable microphone associated with a participant in the simulation, a wearable identifier associated with the participant, and a computer system interoperably coupled to the camera and the microphone and configured to capture data received during the simulation from the camera and data received during the simulation from the wearable microphone, process the data received from the camera and the data received from the wearable microphone, present visual traces indicative of position of the participant on a map of the clinical emergency training area as a function of time, and present audio derived from the wearable microphone in synchronization with the presented visual traces. | 12-31-2015 |
Valeria Grazú Bonavía, Zaragoza ES
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20150293084 | BIOSENSOR COMPRISING METAL NANOPARTICLES - The present invention discloses a biosensor for visual detection of an analyte, based on the light to heat conversion properties of metal nanoparticles: the analyte is visually detected by the color change in the support areas (where the analyte is present), produced as a result of the heat generated by the metal nanoparticles where they are irradiated with an external light source. Use of said biosensor in a method for the detection of analytes is also claimed. | 10-15-2015 |
Valeria Grenci, Roma IT
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20130186544 | MIX FOR OUTER TYRE PORTIONS OF IMPROVED APPEARANCE - A tyre mix containing a cross-linkable, unsaturated-chain polymer base, curing agents, a reinforcing filler, and wax; the wax containing a paraffin wax containing a maximum of 45% by weight of normal paraffin. | 07-25-2013 |
20140206824 | RUBBER COMPOUND MICROWAVE CURING METHOD - A method of curing a compound having a cross-linkable, unsaturated-chain polymer base and a curing system; the method employing microwaves as a form of energy to promote curing reactions; and the curing system including compounds of general formula (I) ([R | 07-24-2014 |
20150329710 | METHOD OF PRODUCING RUBBER TYRE COMPOUNDS - A method of producing rubber tyre compounds, including a first mixing step in which at least one cross-linkable, unsaturated-chain polymer base, silica, and a silane bonding agent in the alkoxymercaptoalkyl-silane class are mixed together; and a final mixing step in which a curing system having at least sulphur and accelerants is added to and mixed with the mix. A nucleophile compound and zinc oxide are mixed with the polymer base at the first mixing step. And the method includes a second mixing step between the first mixing step and the final mixing step, and in which a silane bonding agent in the polysulphide organosilane class is added to and mixed with the mix from the first mixing step. | 11-19-2015 |
Valeria Hoffmanne Fekete, Budapest HU
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20120178729 | CRYSTALLINE FORM I ROSUVASTATIN ZINC SALT - The present invention relates to crystalline Form I rosuvastatin zinc (2:1) salt, method of preparation thereof and use thereof as pharmaceutically active ingredient for the treatment of diseases related to lipid metabolism including hyperlipoproteinemia, hypercholesteremia, dyslipidemia and atherosclerosis. | 07-12-2012 |
Valeria Intini, Putignano IT
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20110167318 | READING METHOD OF A MEMORY DEVICE WITH EMBEDDED ERROR-CORRECTING CODE AND MEMORY DEVICE WITH EMBEDDED ERROR-CORRECTING CODE - A reading method for a memory device with error-correcting encoding envisages the steps of: carrying out a first reading of a plurality of memory locations (A | 07-07-2011 |
Valeria Krasovskaya, Goleta, CA US
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20090176988 | Preparation and Use of Magnesium Amides - The present application relates to mixed Mg/Li amides of the general formula R1R2N—Mg(NR3R4)mX,m zLiY (II) wherein R | 07-09-2009 |
Valeria La Parola, Catania IT
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20160024408 | ONE-POT PROCESS FOR THE PRODUCTION OF BIODIESEL AND GLYCEROL ETHER MIXTURES USEFUL AS BIOFUELS - A process for the conversion of a feedstock containing one or more fatty acid triglycerides to a mixture containing one or more fatty acid alkyl esters and t-alkyl glycerols, including reacting the feedstock with a compound of formula (I): | 01-28-2016 |
Valeria Lifke, Penzberg DE
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20100105073 | METHOD FOR THE PRODUCTION OF ANTIBODIES - The current invention is related to a method for the production of a human monoclonal antibody from a immunodeficient non-human animal, said method comprising contacting a new borne immunodeficient non-human animal with a human fetal liver stem cell (FL cell) to generate an immune transplanted non-human animal (reconstituted animal), subsequently contacting said reconstituted animal with a antigen, collecting from said reconstituted animal a human cell producing human antibody against said antigen, and isolating said antibody from said antibody producing cell. | 04-29-2010 |
20110059093 | USE OF AN ANTI-TAU PS422 ANTIBODY FOR THE TREATMENT OF BRAIN DISEASES - An antibody binding to Tau that is phosphorylated at serine 422 (pS422), which specifically binds to phosphorylated Tau fragment of SEQ ID NO:9 and to Tau pS422, but does not bind to Tau and to phosphorylated MCAK fragment of SEQ ID NO:17. The antibody is useful in the treatment of a Tauopathy. | 03-10-2011 |
20110165082 | METHOD FOR DETERMINING THE ANTI-TUMOR EFFICACY OF MONOCLONAL ANTIBODIES - The present invention relates to a method for determining the anti-tumor efficacy of monoclonal antibodies in pre-clinical rodent testings and the use of said method for the reduction of side testings. | 07-07-2011 |
20110171222 | ANTI-HER3 ANTIBODIES AND USES THEREOF - The present invention relates to antibodies binding to human HER3 (anti-HER3 antibody), methods for their production, pharmaceutical compositions containing said antibodies, and uses thereof. | 07-14-2011 |
20110306094 | METHOD FOR OBTAINING IMMUNOGLOBULIN ENCODING NUCLEIC ACID - The current invention is directed to a method for obtaining a nucleic acid encoding an immunoglobulin variable domain from a single cell comprising the following steps:—performing a first polymerase chain reaction with three to six 5′-primer and one 3′-primer, performing with the product of the first polymerase chain reaction a second polymerase chain reaction with thirteen to sixteen 5′-primer and one 3′-primer, whereby the distance of the binding locations of the primer employed in the second polymerase chain reaction is reduced compared to the first polymerase chain reaction. | 12-15-2011 |
20120195903 | METHOD FOR THE PRODUCTION OF ANTIBODIES - The current invention is related to a method for the production of a human monoclonal antibody from a immundeficient non-human animal, said method comprising contacting a new borne immunodeficient non-human animal with a human fetal liver stem cell (FL cell) to generate an immune transplanted non-human animal (reconstituted animal), subsequently contacting said reconstituted animal with a antigen, collecting from said reconstituted animal a human cell producing human antibody against said antigen, and isolating said antibody from said antibody producing cell. | 08-02-2012 |
20120213774 | Antibodies against human IL33R and uses thereof - An antibody binding to IL33R characterized in that the heavy chain variable domain comprises a CDR3 region of SEQ ID NO:1, a CDR2 region of SEQ ID NO:2 and a CDR1 region of SEQ ID NO:3 and in that the light chain variable domain comprises a CDR3 region of SEQ ID NO:4, a CDR2 region of SEQ ID NO:5 and a CDR1 region of SEQ ID NO:6 or a chimeric, humanized or T cell epitope depleted antibody variant thereof has advantageous properties for the treatment of inflammatory diseases. | 08-23-2012 |
20130189270 | METHOD FOR THE PRODUCTION OF ANTIBODIES - The current invention is related to a method for the production of a human monoclonal antibody from a immundeficient non-human animal, said method comprising contacting a new borne immunodeficient non-human animal with a human fetal liver stem cell (FL cell) to generate an immune transplanted non-human animal (reconstituted animal), subsequently contacting said reconstituted animal with a antigen, collecting from said reconstituted animal a human cell producing human antibody against said antigen, and isolating said antibody from said antibody producing cell. | 07-25-2013 |
20130310541 | USE OF AN ANTI-TAU PS422 ANTIBODY FOR THE TREATMENT OF BRAIN DISEASES - An antibody binding to Tau that is phosphorylated at serine 422 (pS422), which specifically binds to phosphorylated Tau fragment of SEQ ID NO:9 and to Tau pS422, but does not bind to Tau and to phosphorylated MCAK fragment of SEQ ID NO:17. The antibody is useful in the treatment of a Tauopathy. | 11-21-2013 |
20140302015 | ANTIBODIES AGAINST HUMAN IL33R AND USES THEREOF - An antibody binding to IL33R characterized in that the heavy chain variable domain comprises a CDR3 region of SEQ ID NO:1, a CDR2 region of SEQ ID NO:2 and a CDR1 region of SEQ ID NO:3 and in that the light chain variable domain comprises a CDR3 region of SEQ ID NO:4, a CDR2 region of SEQ ID NO:5 and a CDR1 region of SEQ ID NO:6 or a a chimeric, humanized or T cell epitope depleted antibody variant thereof has advantageous properties for the treatment of inflammatory diseases. | 10-09-2014 |
20140377272 | ANTI-HER3 ANTIBODIES AND USES THEREOF - The present invention relates to antibodies binding to human HER3 (anti-HER3 antibody), methods for their production, pharmaceutical compositions containing said antibodies, and uses thereof. | 12-25-2014 |
20140377273 | ANTI-HER3 ANTIBODIES AND USES THEREOF - The present invention relates to antibodies binding to human HER3 (anti-HER3 antibody), methods for their production, pharmaceutical compositions containing said antibodies, and uses thereof. | 12-25-2014 |
20150024434 | METHOD FOR OBTAINING FAB FRAGMENTS FROM SINGLE ANTIBODY PRODUCING CELLS BY MULTIPLEXED CPR IN COMBINATION WITH TaqMan PROBES - Herein is reported a method for a multiplex one tube real-time reverse-transcriptase gene-specific polymerase chain reaction for the amplification and quantification of cognate IgG heavy and light chains encoding nucleic acids (human IgG isotype) from a single cell. | 01-22-2015 |
Valeria Livi, Monza IT
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20110144147 | INJECTABLE PHARMACEUTICAL COMPOSITIONS OF AN ANTHRACENEDIONE DERIVATIVE WITH ANTI-TUMORAL ACTIVITY - Injectable pharmaceutical compositions containing 6,9-bis[(2-aminoethyl)amino]benzo[g]isoquinoline-5,10-dione dimaleate as active ingredient in the form of a lyophilised powder with a carrier selected from lactose and dextran, mixed with sodium chloride. | 06-16-2011 |
Valeria Livi, Milano IT
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20120010415 | PROCESS FOR THE PREPARATION OF 6-(7-((1-AMINOCYCLOPROPYL)METHOXY)-6-METHOXYQUINOLIN-4-YLOXY)-N-METHYL-1-- NAPHTHAMIDE AND SYNTHETIC INTERMEDIATES THEREOF - A process for the preparation in high yields and purity of the compound 6-(7-4(1-aminocyclopropyl)methoxy)-6-methoxyquinolin-4-yloxy)-N-methyl-1-naphthamide of formula (I) and of the pharmaceutically acceptable salts thereof is described. The process has various advantages over those previously described, in particular it avoids the use of acyl azide intermediates and their Curtius rearrangement. Novel intermediates useful for the preparation of compound (I) are also described. | 01-12-2012 |
20140114075 | PROCESS FOR THE PREPARATION OF 6-(7-((1-AMINOCYCLOPROPYL)METHOXY)-6-METHOXYQUINOLIN-4-YLOXY)-N-METHYL-1-- NAPHTHAMIDE AND SYNTHETIC INTERMEDIATES THEREOF - A process for the preparation in high yields and purity of the compound 6-(7-((1-aminocyclopropyl)methoxy)-6-methoxyquinolin-4-yloxy)-N-methyl-1-naphthamide of formula (I) and of the pharmaceutically acceptable salts thereof is described. The process has various advantages over those previously described, in particular it avoids the use of acyl azide intermediates and their Curtius rearrangement. Novel intermediates useful for the preparation of compound (I) are also described. | 04-24-2014 |
20150191429 | Process for the Preparation of 6-(7-((1-Aminocyclopropyl)Methoxy)-6-Methoxyquinolin-4-Yloxy)-N-Methyl-1-- Naphthamide and Synthetic Intermediates Thereof - A process for the preparation in high yields and purity of the compound 6-(7-((1-aminocyclopropyl)methoxy)-6-methoxyquinolin-4-yloxy)-N-methyl-1-naphthamide of formula (I) and of the pharmaceutically acceptable salts thereof is described. The process has various advantages over those previously described, in particular it avoids the use of acyl azide intermediates and their Curtius rearrangement. Novel intermediates useful for the preparation of compound (I) are also described. | 07-09-2015 |
Valeria Livi, Sesto San Giovanni IT
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20100151582 | METHOD FOR DETERMINING THE AMOUNT OF CONJUGATED TAXANE IN POLYGLUT ACID-TAXANE CONJUGATES - The invention relates to a method for determining the amount of conjugated taxane, in particular paclitaxel, in a PGA-taxane conjugate said method comprising: a) reacting the PGA-taxane conjugate with a compound formula (I): R | 06-17-2010 |
Valeria Loreti, Hamburg DE
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20100307428 | FUEL COMPOSITION - A domestic heating fuel composition, comprising (a) a paraffinic hydrocarbon composition comprising at least 90 wt % normal paraffins and/or iso-paraffins comprising from 6 to 24 carbon atoms, wherein the weight ratio of iso-paraffins to normal-paraffins is below 6 to 1, and (b) at least one compound having a C/H molar ratio of above 0.8 and soluble in component (a) at ambient conditions, wherein the component (b) is present in the fuel composition in an amount effective to increase the responsiveness of a yellow/red flame detector to a required threshold level. | 12-09-2010 |
Valeria Lucini, Milano IT
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20100267836 | NOVEL MELATONIN LIGANDS HAVING ANTIDEPRESSANT ACTIVITY AS WELL AS SLEEP INDUCING PROPERTIES - Novel melatonin ligands of Formula I: | 10-21-2010 |
20150045442 | NOVEL MELATONIN LIGANDS HAVING ANTIDEPRESSANT ACTIVITY AS WELL AS SLEEP INDUCING PROPERTIES - Novel melatonin ligands of Formula I: | 02-12-2015 |
Valeria Lulla, Tartu EE
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20110130304 | METHOD FOR CREATING A VIRAL GENOMIC LIBRARY, A VIRAL GENOMIC LIBRARY AND A KIT FOR CREATING THE SAME - A method for creating an alphavirus-based genomic library, comprising a) ligation of foreign sequence (s) from an expression library or a random library into plasmids containing cloned alphaviral cDNA, b) multiplication of the obtained plasmid constructs in bacterial cells, c) direct transfection of the obtained plasmid constructs into mammalian or arthropod cells, characterized in that the sequence of an intron or sequences of introns are inserted into the respective genome of an alphavirus or into the cDNA of an expression vector based on an alphavirus, —the sequence of a viral subgenomic promoter, which is larger than minimal functional promoter is inserted immediately to the 3′ end of the sequences coding the structural proteins of the named alphavirus, —and ribozyme sequence is inserted for creating correct 3′ ends of the alphavirus. | 06-02-2011 |
Valeria Motterle, Schio IT
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20160001301 | Nozzle Separator Bowl - The invention relates to a centrifugal separator bowl ( | 01-07-2016 |
20160001303 | Discharge Nozzle for Nozzle Separator - The invention relates to an outlet nozzle assembly ( | 01-07-2016 |
Valeria Mozzetti, Zurich CH
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20120177607 | OXIDATIVE STRESS RESISTANT BIFIDOBACTERIA - The present invention relates in general to the field of Bifidobacteria. In particular the present invention relates to the field of Bifidobacteria with an improved resistance to oxidative stress. The inventors have identified a Bifido bacterium that exhibits for example an improved H | 07-12-2012 |
Valeria Nikolaenko US
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20160020898 | PRIVACY-PRESERVING RIDGE REGRESSION - A hybrid approach to privacy-preserving ridge regression is presented that uses both homomorphic encryption and Yao garbled circuits. Users in the system submit their data encrypted under a linearly homomorphic encryption. The linear homomorphism is used to carry out the first phase of the algorithm that requires only linear operations. The output of this phase generates encrypted data, in a form that is independent of the number of users n. In a second phase, a Yao garbled circuit that first implements homomorphic decryption and then does the rest of the regression algorithm (as shown, an optimized realization can avoid decryption in the garbled circuit) is evaluated. For this step a Yao garbled circuit approach is much faster than current fully homomorphic encryption schemes. Thus the best of both worlds is obtained by using linear homomorphisms to handle a large data set and using garbled circuits for the heavy non-linear part of the computation. | 01-21-2016 |
Valeria Nikolaenko, Stanford, CA US
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20150381349 | PRIVACY-PRESERVING RIDGE REGRESSION USING MASKS - A method and system for privacy-preserving ridge regression using masks is provided. The method includes the steps of requesting a garbled circuit from a crypto service provider, collecting data from multiple users that has been formatted and encrypted using homomorphic encryption, summing the data that has been formatted and encrypted using homomorphic encryption, applying prepared masks to the summed data, receiving garbled inputs corresponding to prepared mask from the crypto service provider using oblivious transfer, and evaluating the garbled circuit from the crypto service provider using the garbled inputs and masked data. | 12-31-2015 |
20160004874 | A METHOD AND SYSTEM FOR PRIVACY PRESERVING MATRIX FACTORIZATION - A method includes: receiving a set of records from a source, wherein each record in the set of records includes a set of tokens and a set of items, and wherein each record is kept secret from parties other than the source, receiving at least one separate item, and evaluating the set of records and the at least one separate item by using a garbled circuit based on matrix factorization, wherein the output of the garbled circuit includes an item profile for each at least one separate item. An apparatus includes: a processor that communicates with at least one input/output interface, and at least one memory in signal communication with the processor, wherein the processor is configured to perform the method. | 01-07-2016 |
20160036584 | PRIVACY-PRESERVING RIDGE REGRESSION USING PARTIALLY HOMOMORPHIC ENCRYPTION AND MASKS - A method and system for privacy-preserving ridge regression using partially homomorphic encryption and masks is provided. The method includes the steps of requesting a garbled circuit from a crypto service provider, collecting data from multiple users that has been formatted and encrypted using partially homomorphic encryption, summing the data that has been formatted and encrypted using partially homomorphic encryption, applying a prepared masks to the summed data, receiving garbled inputs corresponding to prepared mask from the crypto service provider using oblivious transfer, and evaluating the garbled circuit from the crypto service provider using the garbled inputs and masked data. | 02-04-2016 |
Valeria Parreira, Guelph CA
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20100255022 | VACCINE AGAINST CLOSTRIDIUM PERFRINGENS - There is provided a vaccine for controlling | 10-07-2010 |
20130295127 | VACCINE AGAINST CLOSTRIDIUM PERFRINGENS - There is provided a vaccine for controlling | 11-07-2013 |
Valeria Parreira Pinto, Guelph CA
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20150158917 | NOVEL TOXIN IN TYPE A CLOSTRIDIUM PERFRINGENS - The present disclosure relates to a novel toxin of Type A | 06-11-2015 |
Valeria Pechorin, Brighton, MA US
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20140164829 | RECOVERY FOR LONG RUNNING MULTITHREADED PROCESSES - In response to receiving a checkpoint request from a first task for a process executing in parallel with at least a second task for the process, checkpoint data from the first task is stored to establish a restart point for the first task, wherein the checkpoint data records a current state of the first task, and the checkpoint data from the first task is merged with previously received checkpoint data for the at least second task to create a checkpoint file. In response to restarting the process, the first task and the at least second task are restarted using the checkpoint data in the checkpoint file. | 06-12-2014 |
20140207738 | RECOVERY FOR LONG RUNNING MULTITHREADED PROCESSES - In response to receiving a checkpoint request from a first task for a process executing in parallel with at least a second task for the process, checkpoint data from the first task is stored to establish a restart point for the first task, wherein the checkpoint data records a current state of the first task, and the checkpoint data from the first task is merged with previously received checkpoint data for the at least second task to create a checkpoint file. In response to restarting the process, the first task and the at least second task are restarted using the checkpoint data in the checkpoint file. | 07-24-2014 |
Valeria Perticara', Rome IT
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20090158294 | DYNAMIC CRITICAL-PATH RECALCULATION FACILITY - A method for dynamically recalculating a critical path in a job scheduling system is disclosed. In selected embodiments, the method may include determining when a first job associated with a critical path is substantially complete. The method may further include identifying a successor job of the first job and identifying multiple predecessor jobs of the successor job. The method may then determine whether there is at least one predecessor job that has not completed. In the event there is at least one predecessor job that has not completed, the method may recalculate the critical path. A corresponding apparatus and computer program product for implementing the above-stated method are also disclosed. | 06-18-2009 |
20100023805 | METHOD AND SYSTEM FOR DISASTER RECOVERY BASED ON JOURNALING EVENTS PRUNING IN A COMPUTING ENVIRONMENT - A method and system for automated disaster recovery in an information technology computing system including computing resources, is provided. One implementation involves logging system events in a journaling log file, filtering the events of the log file for each resource and storing the filtered log file, reading the filtered log file, and restarting from a backup file by applying the filtered events to a backup file for recovery. | 01-28-2010 |
20100060079 | METHOD AND SYSTEM FOR ORGANIZING AND OPTIMIZING ELECTRICITY CONSUMPTION - A method and system for managing power consumption by electrical appliances, is provided. One implementation involves obtaining power consumption information for a use cycle of a each of multiple appliances; and automatically scheduling a time slot for an operation cycle of a selected appliance as a function of power consumption by appliance cycles scheduled in that time slot, such that an upper limit of power consumption is not exceeded by the collective power consumption for scheduled appliance cycles in the time slot. | 03-11-2010 |
20100211822 | DISASTER RECOVERY BASED ON JOURNALING EVENTS PRIORITIZATION IN INFORMATION TECHNOLOGY ENVIRONMENTS - Disaster recovery is performed based on journaling events prioritization in information in an information technology environment. One implementation involves prioritizing log file events for scheduling of jobs on a computing system, by logging events concerning each job execution plan, in a log file, and for disaster recovery, prioritizing logged events based on corresponding job urgency and relevance level and performing recovery by reapplying the events of log files in the priority order such that more urgent and relevant jobs are recovered first. | 08-19-2010 |
20100251241 | MANAGING JOB EXECUTION - This disclosure describes monitoring the execution of jobs in a work plan. In an embodiment, a system maintains a risk level associated with the critical job to represent whether the execution of a job preceding the critical job has a problem, and it maintains the list associated with the critical job so as to quickly identify the preceding job which may cause a delay to the critical job execution. | 09-30-2010 |
20120173029 | ADAPTIVE APPLIANCE SCHEDULING FOR MANAGING ELECTRICITY CONSUMPTION - A scheduler detects a change in one of an electricity consumption pattern and appliance cycle scheduling that affects electricity consumption in a future time slot of an appliance cycle schedule for a plurality of appliances. The appliance cycle schedule comprises a plurality of future time slots. Appliances scheduled for use during the future time slot are determined. A total electricity consumption for the future time slot is then computed. The total electricity consumption comprises a sum of predicted background electricity consumption during the future time slot and predicted appliance cycle electricity consumption during the future time slot. It is determined that the total electricity consumption exceeds a threshold electricity consumption associated with an electric meter associated with the plurality of appliances. A new appliance cycle schedule with each of the plurality of future time slots having total electricity consumption below the threshold electricity consumption is generated. | 07-05-2012 |
20120260260 | Managing Job Execution - Various embodiments involve monitoring the execution of jobs in a work plan. For example, a system maintains a risk level associated with the critical job may be maintained to represent whether the execution of a job preceding the critical job has a problem, and a list associated with the critical job may be maintained so as to quickly identify the preceding job which may cause a delay to the critical job execution. | 10-11-2012 |
20140196057 | Managing Job Execution - This disclosure describes monitoring the execution of jobs in a work plan. In an embodiment, a system maintains a risk level associated with the critical job to represent whether the execution of a job preceding the critical job has a problem, and it maintains the list associated with the critical job so as to quickly identify the preceding job which may cause a delay to the critical job execution. | 07-10-2014 |
Valeria Pittala', Catania IT
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20090221632 | Bicyclo-Pyrazoles and Pharmaceutical Compositions Comprising Them - Bicyclo-pyrazole compounds of formula (I), as herein defined, are useful for treating diseases linked to disregulated protein kinases. | 09-03-2009 |
20100286223 | Condensed Heterocyclic Pyrazole Derivatives as Kinase Inhibitors - Bicyclo-pyrazole compound of formula (I) and pharmaceutically acceptable salts thereof, as defined in the specification, processes for their preparation, combinatorial libraries comprising a plurality of them and pharmaceutical compositions thereof, are herewith disclosed: the compounds of the invention are useful, in therapy, as protein kinase inhibitors, for instance in the treatment of cancer. | 11-11-2010 |
Valeria Querol Garcia, Mexico City MX
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20130281985 | Three-Lobe Drainage Hose - A drainage system includes a drainage tube, a tubular coupling, and a drainage hose. The drainage tube defines an inner passage and terminating in a first drainage end and a second drainage end. The tubular coupling has a first thickness that runs throughout the coupling and forms a passage and a stop determined by a second thickness. The drainage hose is formed by a profile which runs along a length of the drainage hose and terminates in a first drainage end and a second drainage end. | 10-24-2013 |
Valeria Querol Garica, Mexico City MX
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20100004678 | AMBIDEXTROUS GRASPING SYSTEM FOR A MEDICAL INSTRUMENT - A medical instrument with an ambidextrous grasping system, which includes: a single elongate arm and a double elongate arm, which are joined to one another by a joining means at the rear ends, a sliding blocking mechanism which is connected and disconnected by means of a vertical movement, and tips for medical use which are located at the front end, wherein the blocking mechanism is activated by slight pressure exerted by the user in the grasping area, in order to activate and deactivate the mechanism, whilst maintaining a constant distance between the two arms in the grasping area, in order to improve the comfort of the user; the said instrument with a grasping system does not have a pivoting point, thus facilitating its cleaning, maintenance and use, and in addition this grasping system is simple to manufacture and has a low cost. | 01-07-2010 |
Valeria Raia, Milano IT
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20130310329 | COMBINED THERAPY FOR CYSTIC FIBROSIS - There is disclosed a combination of inhibitors of Tissue Transglutaminase (TG2), inhibitors of reactive oxygen species (ROS) and CFTR channel activators (potentiators) for separate, sequential or simultaneous administration to CF patients carrying the ΔF508-CFTR mutation, and pharmaceutical compositions thereof. | 11-21-2013 |
20150328203 | COMBINED THERAPY FOR CYSTIC FIBROSIS - There is disclosed a combination of inhibitors of Tissue Transglutaminase (TG2), inhibitors of reactive oxygen species (ROS) and CFTR channel activators (potentiators) for separate, sequential or simultaneous administration to CF patients carrying the ΔF508-CFTR mutation, and pharmaceutical compositions thereof. | 11-19-2015 |
Valeria Ramaglia, Amsterdam NL
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20100143344 | COMPLEMENT INHIBITION FOR IMPROVED NERVE REGENERATION - The present invention relates to methods and medicaments used for treating conditions that require axonal regeneration, e.g. in mammals affected by injury or disease of the central or peripheral nervous system. The medicaments used in these methods facilitate axonal regeneration by inhibition of the complement system. Conditions requiring axonal regeneration that may be treated in accordance with the invention include physical injuries as well as neurodegenerative disorders of the peripheral or central nervous system. | 06-10-2010 |
20140255395 | COMPLEMENT INHIBITION FOR IMPROVED NERVE REGENERATION - The present invention relates to methods and medicaments used for treating conditions that require axonal regeneration, e.g. in mammals affected by injury or disease of the central or peripheral nervous system. The medicaments used in these methods facilitate axonal regeneration by inhibition of the complement system. Conditions requiring axonal regeneration that may be treated in accordance with the invention include physical injuries as well as neurodegenerative disorders of the peripheral or central nervous system. | 09-11-2014 |
Valeria Runza, Penzberg DE
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20140370019 | BISPECIFIC ANTIBODIES SPECIFIC FOR FAP AND DR5, ANTIBODIES SPECIFIC FOR DR5 AND METHODS OF USE - The present invention relates to bispecific antibodies comprising at least one antigen binding site specific for DR5 and at least one antigen binding site specific for FAP, antibodies specific for DR5, methods for their production, pharmaceutical compositions containing said antibodies, and uses thereof. | 12-18-2014 |
Valeria Sandei, Rome IT
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20140343927 | SYSTEM AND METHOD FOR MEANING DRIVEN PROCESS AND INFORMATION MANAGEMENT TO IMPROVE EFFICIENCY, QUALITY OF WORK AND OVERALL CUSTOMER SATISFACTION - A customer service system for providing enhanced guidance and resources to service agents and providing an enhance ability to select service agents that are best suited to address specific customers and specific customer needs, and methods for manufacturing and using same. The customer service system includes a system server with a semantic engine configured to analyze customer contact events and customize service agent interfaces based on determined customer needs. | 11-20-2014 |
Valeria Sanginario, Pozzuoli (napoli) IT
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20110091554 | INJECTABLE COMPOSITE MATERIAL SUITABLE FOR USE AS A BONE SUBSTITUTE - The invention relates to a new injectable composite material suitable for use as a bone substitute. The composite material according to the invention comprises a reactive ceramic phase based on tricalcium phosphate and an organic phase comprising a polyvinyl alcohol hydrogel. By varying the concentration of the two phases it is possible to modulate the mechanical and injectability properties of the material. | 04-21-2011 |
Valeria Sanginario, Napoli IT
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20080220086 | Injectable Composite Material Suitable for Use as a Bone Substitute - The invention relates to a new injectable composite material suitable for use as a bone substitute. The composite material according to the invention comprises a reactive ceramic phase based on tricalcium phosphate and an organic phase comprising a polyvinyl alcohol hydrogel. By varying the concentration of the two phases it is possible to modulate the mechanical and injectability properties of the material. | 09-11-2008 |
Valeria Stoppello, Capital Federal AR
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20100239721 | METHOD AND APPARATUS TO FACILITATE ENCAPSULATING AN EDIBLE SUBSTANCE - An apparatus is provided comprising an edible substance, a discrete sheet of flexible film, and an adhesive disposed on the flexible film in a pattern that surrounds an adhesive-free space that is sized to accommodate the edible substance. The adhesive preferably does not extend to at least one edge of the flexible film. Portions of the adhesive contact other portions of the adhesive such that the discrete sheet encapsulates the edible substance, and the discrete sheet is twisted in at least one area that includes the adhesive. | 09-23-2010 |
Valeria Strada, Haifa IL
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20120208280 | BRUCELLA PHAGE POLYNUCLEOTIDES AND USES THEREOF - An isolated polynucleotide is disclosed which comprises a nucleic acid sequence of a | 08-16-2012 |
20140248607 | BRUCELLA PHAGE POLYNUCLEOTIDES AND USES THEREOF - An isolated polynucleotide is disclosed which comprises a nucleic acid sequence of a | 09-04-2014 |
Valeria Szijárto, Vienna AT
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20150246107 | NOVEL LIVE ATTENUATED SHIGELLA VACCINE - A live attenuated | 09-03-2015 |
20150322138 | MDR E. COLI SPECIFIC ANTIBODY - The subject relates to an isolated antibody that specifically binds to O25b antigen of multi drug resistant (MDR) | 11-12-2015 |
Valeria Van Axel Castelli, Rome IT
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20120184676 | COMPATIBLISED POLYOLEFIN COMPOSITIONS - Compatibilised polyolefin compositions combining the positive properties of their respective components by using an olefinic di- or triblock copolymer as compatibiliser to generate a finely dispersed phase structure in the molten state and to improve adhesion between the blend components in the solid state, while not compromising processability of the polyolefin composition. | 07-19-2012 |
Valeria Vinti, Torre Del Greco IT
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20140011918 | POLYMERIC FORMULATIONS WITH CHEMICALLY ADJUSTABLE RHEOLOGY FOR THE MANUFACTURE OF PREPREGS AND ARTICLES MADE OF COMPOSITE MATERIAL - A polymeric formulation comprising at least one first epoxy resin having a density between 100 and 10,000 Pa·s, a blocked isocyanate, a polymer comprising hydroxy functional groups, a thermoplastic resin and a cross-linking agent, the polymer comprising hydroxyl functional groups with a hydroxyl content in the range 0.65 to 0.95 meq/g, the isocyanate-equivalents-to-polymer-OH-equivalents rate being in the range 0.60 to 1.1. The first epoxy resin is substantially semisolid at room temperature, the formulation comprising at least one second epoxy resin substantially liquid at room temperature, the first and second epoxy resins being present in a weight ratio from 60:40 to 80:20. These formulations are advantageously used for manufacturing prepregs and articles of composite material according to a dry winding process. By virtue of improved stability, a higher glass transition temperature, and a rheological profile result which can be chemically tailored to the needs of the impregnation/dry winding process. | 01-09-2014 |
Valeria Visconte, Cleveland, OH US
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20130316014 | METHODS FOR PREDICTING PROGNOSIS OF A SUBJECT WITH A MYELOID MALIGNANCY - One aspect of the present disclosure includes a method for predicting the prognosis of a subject with a myeloid malignancy. One step of the method includes obtaining a biological sample from the subject. Next, at least one mutation in a spliceosome-associated protein, or a polynucleotide encoding the spliceosome-associated protein that results in defective splicing can be detected in the biological sample. The presence of at least one mutation in the spliceosome-associated protein, or a polynucleotide encoding the spliceosome-associated protein, is indicative of the subject's prognosis. | 11-28-2013 |
Valeria Wittamer, Waterloo BE
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20090047741 | Compositions and methods comprising a ligand of chemerin R - The present invention relates to a G-protein coupled receptor and a novel ligand therefor. The invention provides screening assays for the identification of candidate compounds which modulate the activity of the G-protein coupled receptor, as well as assays useful for the diagnosis and treatment of a disease or disorder related to the dysregulation of G-protein coupled receptor signaling. | 02-19-2009 |
20090081729 | Compositions and Methods Comprising a Ligand of ChemerinR - The present invention relates to a G-protein coupled receptor and a novel ligand therefor. The invention provides screening assays for the identification of candidate compounds which modulate the activity of the G-protein coupled receptor, as well as assays useful for the diagnosis and treatment of a disease or disorder related to the dysregulation of G-protein coupled receptor signaling. | 03-26-2009 |
20100009345 | Compositions and methods comprising a ligand of chemerin R - The present invention relates to a G-protein coupled receptor and a novel ligand therefor. The invention provides screeing assays for the identification of candidate compounds which modulate the activity of the G-protein coupled receptor, as well as assays useful for the diagnosis and treatment of a disease or disorder related to the dysregulation of G-protein coupled receptor signaling. | 01-14-2010 |