Patent application number | Description | Published |
20090103345 | Three-dimensional memory module architectures - Various embodiments of the present invention are directed to stacked memory modules. In one embodiment of the present invention, a memory module comprises at least one memory-controller layer stacked with at least one memory layer. Fine pitched through vias (e.g., through silicon vias) extend approximately perpendicular to a surface of the at least one memory controller through the stack providing electronic communication between the at least one memory controller and the at least one memory layers. Additionally, the memory-controller layer includes at least one external interface configured to transmit data to and from the memory module. Furthermore, the memory module can include an optical layer. The optical layer can be included in the stack and has a bus waveguide to transmit data to and from the at least one memory controller. The external interface can be an optical external interface which interfaces with the optical layer. | 04-23-2009 |
20110113208 | STORING CHECKPOINT DATA IN NON-VOLATILE MEMORY - Methods and systems for storing checkpoint data in non-volatile memory are described. According to one embodiment, a data storage method includes executing an application using processing circuitry and during the execution, writing data generated by the execution of the application to volatile memory. An indication of a checkpoint is provided after writing the data. After the indication has been provided, the method includes copying the data from the volatile memory to non-volatile memory and, after the copying, continuing the execution of the application. The method may include suspending execution of the application. According to another embodiment, a data storage method includes receiving an indication of a checkpoint associated with execution of one or more applications and, responsive to the receipt, initiating copying of data resulting from execution of the one or more applications from volatile memory to non-volatile memory. In some embodiments, the non-volatile memory may be solid-state non-volatile memory. | 05-12-2011 |
20110134930 | PACKET-BASED NETWORKING SYSTEM - One embodiment of the present invention is directed to a networking system comprising a sending device, a receiving device, electronic communications components and transmission media through which the sending device and receiving device exchange data packets, and a networking protocol implemented in executable routines, firmware, hardware, or a combination of two or more of executable routines, firmware, hardware that provides for transmission of data in an ordered set of data packets through a sequence established between the sending device and receiving device as a result of transmitting a first data packet from the sending device to the receiving device and returning an acknowledgement by the receiving device to the sending device. | 06-09-2011 |
20110176804 | Method And Systems For Implementing High-radix Switch Topologies On Relatively Lower-radix Switch Physical Networks - Embodiments of the present invention are directed to implementing high-radix switch topologies on relatively lower-radix physical networks. In one embodiment, the method comprises constructing the physical network ( | 07-21-2011 |
20110280579 | ENERGY-EFFICIENT AND FAULT-TOLERANT RESONATOR-BASED MODULATION AND WAVELENGTH DIVISION MULTIPLEXING SYSTEMS - Systems and methods are provided for modulating, channels in dense wavelength division multiplexing (“DWDM”) systems. In one aspect, a modulation and wavelength division multiplexing system includes a channel source and a waveguide tree structure disposed on a substrate. The tree structure includes waveguides branching from a root waveguide. The waveguides include two or more terminus waveguides coupled to the channel source. The system also includes one or more modulator arrays disposed on the substrate. Each modulator array is optically coupled to one of the two or more terminus waveguides and is configured to modulate channels injected into a terminus waveguide from the channel source to produce corresponding optical signals that propagate from the terminus waveguide along one or more of the waveguides to the root waveguide. | 11-17-2011 |
20110286743 | FLOW-CONTROL METHODS AND SYSTEMS FOR MULTIBUS SYSTEMS - Methods and systems are provided that prevent buffer overflow in multibus systems. In one aspect, a method for controlling the flow of data in a multibus system includes, for each node having an associated broadcast bus in the multibus system, generating status information regarding available data storage space of each receive buffer of the node. The method includes broadcasting the status information to the other nodes connected to the broadcast bus and collecting status information regarding the available storage space of receive buffers of the other nodes connected to the broadcast bus. The method also includes determining whether or not to send data from the node to at least one of the other nodes over the broadcast bus based on the collected status information. | 11-24-2011 |
20120020242 | METHODS AND APPARATUS TO DETERMINE AND IMPLEMENT MULTIDIMENSIONAL NETWORK TOPOLOGIES - Methods and apparatus to determine and implement multidimensional network topologies are disclosed. An example method disclosed herein comprises receiving an input parameter for determining a multidimensional network topology for a network interconnecting a plurality of devices, and determining a set of multidimensional network topologies, each multidimensional network topology of the set comprising a respective plurality of nodes to interconnect the plurality of devices, each node in each multidimensional network topology of the set being fully connected with all neighbor nodes in each dimension of the multidimensional network topology, and each multidimensional network topology of the set satisfying a first constraint based on the input parameter. | 01-26-2012 |
20120059983 | PREDICTOR-BASED MANAGEMENT OF DRAM ROW-BUFFERS - A method for managing memory includes storing a history of accesses to a memory page, and determining whether to keep the memory page open or to close the memory page based on the stored history. A memory system includes a plurality of memory cells arranged in rows and columns, a row buffer, and a memory controller configured to manage the row buffer at a per-page level using a history-based predictor. A non-transitory computer readable medium is also provided containing instructions therein, wherein the instructions include storing an access history of a memory page in a lookup table, and determining an optimal closing policy for the memory page based on the stored histories. The histories can include access numbers or access durations. | 03-08-2012 |
20120105177 | RESONATOR SYSTEMS AND METHODS FOR TUNING RESONATOR SYSTEMS - Tunable resonator systems and methods for tuning resonator systems are disclosed. In one aspect, a resonator system includes an array of resonators disposed adjacent to a waveguide, at least one temperature sensor located adjacent to the array of resonators, and a resonator control electronically connected to the at least one temperature sensor. Each resonator has a resonance frequency in a resonator frequency comb and channels with frequencies in a channel frequency comb are transmitted in the waveguide. Resonance frequencies in the resonator frequency comb are to be adjusted in response to ambient temperature changes detected by the at least one temperature sensors to align the resonance frequency comb with the channel frequency comb. | 05-03-2012 |
20130058607 | OPTICAL INTERCONNECT FABRICS AND OPTICAL SWITCHES - Optical interconnect fabrics and optical switches are disclosed. In one aspect, an optical interconnect fabric comprises one or more bundles of optical broadcast buses. Each optical broadcast bus is optically coupled at one end to a node and configured to transmit optical signals generated by the node. The optical fabric also includes a number of optical tap arrays distributed along each bundle of optical broadcast buses. Each optical tap array is configured to divert a portion of the optical power associated with the optical signals carried by a bundle of optical broadcast buses to one of the nodes. | 03-07-2013 |
20130251378 | TWO-PHASE OPTICAL COMMUNICATION METHODS AND OPTICAL BUS SYSTEMS FOR IMPLEMENTING THE SAME - Various embodiments of the present invention are directed to methods and systems for transmitting optical signals from a source to a plurality of receiving devices. In one method embodiment, an optical enablement signal is transmitted from the source to the plurality of receiving devices. The target receiving device responds to receiving the optical enablement signal by preparing to receive one or more optical data signals. The source transmits the one or more optical data signals to the target receiving device. The remaining receiving devices do not receive the one or more optical data signals. | 09-26-2013 |
20140040518 | MEMORY INTERFACE - The present disclosure provides a method for processing memory access operations. The method includes determining a fixed response time based at least in part, on a total memory latency of a memory module. The method also includes identifying an available time slot for receiving return data from the memory module over a data bus, wherein the time difference between a current clock cycle and the available time slot is greater than or equal to the fixed response time. The method also includes creating a first slot reservation by reserving the available time slot. The method also includes issuing as read request to the memory module over the data bus, wherein the read request is issued at a clock cycle determined by subtracting the fixed response time from a time of the first slot reservation. | 02-06-2014 |
20140173170 | MULTIPLE SUBARRAY MEMORY ACCESS - A multiple subarray-access memory system is disclosed. The system includes a plurality of memory chips, each including a plurality of subarrays and a memory controller in communication. with the memory chips, the memory controller to receive a memory fetch width (“MFW”) instruction during an operating system start-up and responsive to the MFW instruction to fix a quantity of the subarrays that will be activated in response to memory access requests. | 06-19-2014 |
Patent application number | Description | Published |
20080286467 | METHOD OF USE FOR PHOTOPATTERNABLE DIELECTRIC MATERIALS FOR BEOL APPLICATIONS - A method. The method includes dip coating a film of a composition on a silicon wafer substrate. The composition includes a polymer blend of a first polymer and a second polymer. The first polymer is a substituted silsesquioxane copolymer. The second polymer is a polysilsesquioxane having silanol end groups. The composition includes a photosensitive acid generator, an organic base, and an organic crosslinking agent. The film is patternwise imaged and at least one region is exposed to radiation having a wavelength of about 248 nanometers. The film is baked, resulting in inducing crosslinking in the film. The film is developed resulting in removal of base-soluble unexposed regions of the film, wherein a relief pattern from the film remains. The relief pattern is cured at a temperature between about 300° C. and about 450° C., and the curing utilizes a combination of thermal treatment with UV radiation. | 11-20-2008 |
20090081418 | SPIN-ON ANTIREFLECTIVE COATING FOR INTEGRATION OF PATTERNABLE DIELECTRIC MATERIALS AND INTERCONNECT STRUCTURES - The present invention provides a method of fabricating an interconnect structure in which a patternable low-k material replaces the need for utilizing a separate photoresist and a dielectric material. Specifically, this invention relates to a simplified method of fabricating single-damascene and dual-damascene low-k interconnect structures with at least one patternable low-k dielectric and at least one inorganic antireflective coating. In general terms, a method is provided that includes providing at least one patternable low-k material on a surface of an inorganic antireflective coating that is located atop a substrate. The inorganic ARC is liquid deposited and comprises a polymer that has at least one monomer unit comprising the formula M-R | 03-26-2009 |
20090233226 | PHOTOPATTERNABLE DIELECTRIC MATERIALS FOR BEOL APPLICATIONS AND METHODS FOR USE - Compositions, a method, and a photopatternable blend. The compositions include a blend of a first and a second polymer. The first polymer is a substituted silsesquioxane copolymer. The second polymer is a substituted silsesquioxane polymer. The second polymer is configured to undergo chemical crosslinking with the first polymer, the second polymer, or a combination thereof, upon exposure to light, thermal energy, or a combination thereof. The compositions include a photosensitive acid generator. The method includes forming a film. The film is patternwise imaged, and at least one region is exposed to radiation. After the imaging, the film is baked, wherein at least one exposed region is rendered substantially soluble. After the baking, the film is developed, wherein a relief pattern remains. The relief pattern is exposed to radiation. The relief pattern is baked. The relief pattern is cured. A chemically amplified positive-tone photopatternable blend is also described. | 09-17-2009 |
20090291389 | PHOTOPATTERNABLE DIELECTRIC MATERIALS FOR BEOL APPLICATIONS AND METHODS FOR USE - A method and a composition. The composition includes at least one carbosilane-substituted silsesquioxane polymer which crosslinks in the presence of an acid. The at least one carbosilane-substituted silsesquioxane polymer is soluble in aqueous base. The method includes forming a coating on a substrate. The coating includes one or more carbosilane-substituted silsesquioxane polymers. The carbosilane-substituted silsesquioxane polymer is soluble in aqueous base. The coating is exposed to radiation, resulting in generating a latent pattern in the coating. The exposed coating is baked at a first temperature less than about 150° C. The baked coating is developed, resulting in forming a latent image from the latent pattern in the baked coating. The latent image is cured at a second temperature less than about 500° C. | 11-26-2009 |
20100207276 | SPIN-ON ANTIREFLECTIVE COATING FOR INTEGRATION OF PATTERNABLE DIELECTRIC MATERIALS AND INTERCONNECT STRUCTURES - The present invention provides a method of fabricating an interconnect structure in which a patternable low-k material replaces the need for utilizing a separate photoresist and a dielectric material. Specifically, this invention relates to a simplified method of fabricating single-damascene and dual-damascene low-k interconnect structures with at least one patternable low-k dielectric and at least one inorganic antireflective coating. In general terms, a method is provided that includes providing at least one patternable low-k material on a surface of an inorganic antireflective coating that is located atop a substrate. The inorganic ARC is liquid deposited and comprises a polymer that has at least one monomer unit comprising the formula M-R | 08-19-2010 |
20110083887 | PHOTO-PATTERNABLE DIELECTRIC MATERIALS CURABLE TO POROUS DIELECTRIC MATERIALS, FORMULATIONS, PRECURSORS AND METHODS OF USE THEREOF - Silsesquioxane polymers that cure to porous silsesquioxane polymers, silsesquioxane polymers that cure to porous silsesquioxane polymers in negative tone photo-patternable dielectric formulations, methods of forming structures using negative tone photo-patternable dielectric formulations containing silsesquioxane polymers that cure to porous silsesquioxane polymers, structures containing porous silsesquioxane polymers and monomers and method of preparing monomers for silsesquioxane polymers that cure to porous silsesquioxane polymers. | 04-14-2011 |
20120040289 | CHEMICALLY AMPLIFIED SILSESQUIOXANE RESIST COMPOSITIONS - The present invention provides chemically amplified silsesquioxane polymers for preparing masks using e-beam lithography. The silsesquioxane polymers have reactive sidechains that in the presence of an acid undergo acid catalyzed rearrangement to generate reactive functionalities that crosslink to form Si—O—Si bonds. The reactive side-chains comprise β- and γ-substituted alkyl groups bound to the silicon of the silsesquioxane polymer. The substituent of the β- and γ-substituted alkyl group is an electron withdrawing group. Resists generated with the chemically amplified silsesquioxane polymers of the present invention and imaged with e-beams have resolution of ≦60 nm line/space. | 02-16-2012 |
20130189836 | PHOTO-PATTERNABLE DIELECTRIC MATERIALS CURABLE TO POROUS DIELECTRIC MATERIALS, FORMULATIONS, PRECURSORS AND METHODS OF USE THEREOF - Silsesquioxane polymers that cure to porous silsesquioxane polymers, silsesquioxane polymers that cure to porous silsesquioxane polymers in negative tone photo-patternable dielectric formulations, methods of forming structures using negative tone photo-patternable dielectric formulations containing silsesquioxane polymers that cure to porous silsesquioxane polymers, structures containing porous silsesquioxane polymers and monomers and method of preparing monomers for silsesquioxane polymers that cure to porous silsesquioxane polymers. | 07-25-2013 |
20130327714 | COMPOSITE MEMBRANE WITH MULTI-LAYERED ACTIVE LAYER - A thin film composite membrane includes an active layer on a support membrane, wherein the active layer includes at least two chemically distinct first and second crosslinked polyamide film sub-layers. The first film sub-layer includes a polyamide unit; and the second film sub-layer includes a copolyamide with two chemically distinct polyamide units. The first film sub-layer is closer to the support than is the second film sub-layer. | 12-12-2013 |
20140138863 | METHODS OF FORMING NANOPARTICLES USING SEMICONDUCTOR MANUFACTURING INFRASTRUCTURE - A method of preparing particles comprises forming by optical lithography a topographic template layer disposed on a surface of a substrate, which is suitable for spin casting. The template layer comprises a non-crosslinked template polymer having a pattern of independent wells therein for molding independent particles. Spin casting a particle-forming composition onto the template layer forms a composite layer comprising the template polymer and the particles disposed in the wells. The composite layer is removed from the substrate using a stripping agent that dissolves the template polymer without dissolving the particles. The particles are then isolated. | 05-22-2014 |
Patent application number | Description | Published |
20090219679 | Fire resistant and water resistant enclosure for operable computer digital data storage device - A fire resistant and water resistant enclosure for an operable computer digital data storage device is provided. The enclosure has walls made of gypsum or concrete and, in one embodiment, has two small ventilation openings which remain open during normal operation of the digital data storage device and during the presence of fire. This embodiment has no moving parts. In the presence of fire, air and superheated steam from inside the enclosure expand and flow outwardly through the ventilation passageways. As those gases flow outwardly, they simultaneously block or prevent the transfer of heat from the exterior fire inwardly through those passageways. A water resistant pouch or coating surrounding the storage device prevents damage from flood, water, steam generated by the insulation or smoke from passing through said passageways and damaging the storage device. Another embodiment is provided utilizing one or more movable hatches which, in the presence of fire, cannot completely close, allowing superheated steam to escape from the enclosure yet during normal operation allow for better ventilation and cooling. A method is also provided for protecting the data storage device wherein the walls of the enclosure are supersaturated with water. The walls are coated with a vapor barrier such as plastic skin, plastic container or wax to prevent evaporation of water. In the presence of fire, the vapor barrier melts and the excess water stored in the walls absorbs latent heat of vaporization and extends the amount of time over which the enclosure is able to protect the storage device from damage. | 09-03-2009 |
20110286173 | Low cost rugged portable data storage device and docking station - A low cost, water resistant, rugged and enclosed portable digital data storage device is provided. A two piece enclosure includes a monolithic housing and a cover, both preferably metallic. A passageway is formed in a side wall of the enclosure for plugging an external power and data line into an internal connector which extends into or adjacent the passageway. A liquid water resistant epoxy is applied over the internal connector and adjacent the passageway prior to applying the cover. The result is a low cost, water resistant enclosure with water resistant passageway for power and data lines that remains water resistant whether the external power and data lines are connected to the digital data storage device or not. A fire resistant docking station is also provided, into which the portable data storage device may be easily connected to a primary computer for transferring data. | 11-24-2011 |
Patent application number | Description | Published |
20080233116 | Human monoclonal antibodies to CTLA-4 - In accordance with the present invention, there are provided fully human monoclonal antibodies against human cytotoxic T-lymphocyte antigen 4 (CTLA-4). Nucleotide sequences encoding and amino acid sequences comprising heavy and light chain immunoglobulin molecules, particularly contiguous heavy and light chain sequences spanning the complementarity determining regions (CDRs), specifically from within FR1 and/or CDR1 through CDR3 and/or within FR4, are provided. Further provided are antibodies having similar binding properties and antibodies (or other antagonists) having similar functionality as antibodies disclosed herein. | 09-25-2008 |
20080233122 | Human monoclonal antibodies to CTLA-4 - In accordance with the present invention, there are provided fully human monoclonal antibodies against human cytotoxic T-lymphocyte antigen 4 (CTLA-4). Nucelotide sequences encoding and amino acid sequences comprising heavy and light chain immunoglobulin molecules, particularly contiguous heavy and light chain sequences spanning the complementarity determining regions (CDRs), specifically from within FR1 and/or CDR1 through CDR3 and/or within FR4, are provided. Further provided are antibodies having similar binding properties and antibodies (or other antagonists) having similar functionality as antibodies disclosed herein. | 09-25-2008 |
20090274688 | Antibodies to OPGL - Antibodies that interact with osteoprotegerin ligand (OPGL) are described. Methods of treating osteopenic disorders by administering a pharmaceutically effective amount of antibodies to OPGL are described. Methods of detecting the amount of OPGL in a sample using antibodies to OPGL are described. | 11-05-2009 |
20120045442 | HUMAN MONOCLONAL ANTIBODIES TO CTLA-4 - In accordance with the present invention, there are provided fully human monoclonal antibodies against human cytotoxic T-lymphocyte antigen 4 (CTLA-4). Nucelotide sequences encoding and amino acid sequences comprising heavy and light chain immunoglobulin molecules, particularly contiguous heavy and light chain sequences spanning the complementarity determining regions (CDRs), specifically from within FR1 and/or CDR1 through CDR3 and/or within FR4, are provided. Further provided are antibodies having similar binding properties and antibodies (or other antagonists) having similar functionality as antibodies disclosed herein. | 02-23-2012 |
20120087923 | Antibodies to OPGL - Antibodies that interact with osteoprotegerin ligand (OPGL) are described. Methods of treating osteopenic disorders by administering a pharmaceutically effective amount of antibodies to OPGL are described. Methods of detecting the amount of OPGL in a sample using antibodies to OPGL are described. | 04-12-2012 |
20120148597 | HUMAN MONOCLONAL ANTIBODIES TO CTLA-4 - In accordance with the present invention, there are provided fully human monoclonal antibodies against human cytotoxic T-lymphocyte antigen 4 (CTLA-4). Nucleotide sequences encoding and amino acid sequences comprising heavy and light chain immunoglobulin molecules, particularly contiguous heavy and light chain sequences spanning the complementarity determining regions (CDRs), specifically from within FR1 and/or CDR1 through CDR3 and/or within FR4, are provided. Further provided are antibodies having similar binding properties and antibodies (or other antagonists) having similar functionality as antibodies disclosed herein. | 06-14-2012 |
20140099325 | HUMAN MONOCLONAL ANTIBODIES TO CTLA-4 - In accordance with the present invention, there are provided fully human monoclonal antibodies against human cytotoxic T-lymphocyte antigen 4 (CTLA-4). Nucleotide sequences encoding and amino acid sequences comprising heavy and light chain immunoglobulin molecules, particularly contiguous heavy and light chain sequences spanning the complementarity determining regions (CDRs), specifically from within FR1 and/or CDR1 through CDR3 and/or within FR4, are provided. Further provided are antibodies having similar binding properties and antibodies (or other antagonists) having similar functionality as antibodies disclosed herein. | 04-10-2014 |
20140134157 | ANTIBODIES TO OPGL - Antibodies that interact with osteoprotegerin ligand (OPGL) are described. Methods of treating osteopenic disorders by administering a pharmaceutically effective amount of antibodies to OPGL are described. Methods of detecting the amount of OPGL in a sample using antibodies to OPGL are described. | 05-15-2014 |
Patent application number | Description | Published |
20080249324 | Process For Preparing 1,3-Dibromoacetone, 1-3-Dichloroacetone and Epichlorohydrin - A process for preparing 1,3-dibromoacetone, 1-3-dichloroacetone and epichlorohydrin which comprises: (a) reacting acetone with 2 moles of bromine to make a mixture of brominated acetone derivatives and byproduct hydrogen bromide; (b) equilibrating the mixture of brominated acetone derivatives and hydrogen bromide to produce 1,3-dibromoacetone as the major product; (c) crystallizing the 1,3-dibromoacetone; and (d) isolating the 1,3-dibromoacetone. The process may further include the steps of (e) reacting the 1,3-dibromoacetone with a chloride source to produce 1,3-dichloroacetone; (f) hydrogenating the isolated 1,3-dichloroacetone to produce 1,3-dichlorohydrin; and (g) cyclizing the 1,3-dichlorohydrin with a base to produce epichlorohydrin. | 10-09-2008 |
20100179354 | NOVEL ALKOXY-ETHERS AND ALKOXYLATES THEREOF - Novel 1,3-dialkyloxy-2-propanol and alkoxylates thereof may be prepared in good yield by a convenient process comprising adding epichlorohydrin to a stoichiometric excess of alcohol, wherein the ratio of alcohol:epichlorohydrin is at least about 3:1, preferably in the presence of a Group 1A metal hydroxide and a phase transfer catalyst. The result shows excellent selectivity of to the 1,3-substitution positions, and the alkyl chain may be saturated or unsaturated and may contain one or more heteroatoms. The alkoxylates may include repeating alkoxy units in the 2-position. The compositions are useful as surfactants, diluents, and the like. | 07-15-2010 |
Patent application number | Description | Published |
20090010966 | MODIFIED DIPHTHERIA TOXINS - The present application relates to compositions of modified diphtheria toxin and fusion proteins containing modified diphtheria toxin that reduce binding to vascular endothelium or vascular endothelial cells, and therefore, reduce the incidence of Vascular Leak Syndrome, as well as methods of making the compositions. The present application also relates to a polypeptide toxophore from a modified diphtheria toxin, where the modification is at least one amino acid residue at the amino acid residues 6-8, 28-30 or 289-291 of an unmodified native diphtheria toxin. Also described are fusion proteins which contain a modified diphtheria toxin and a non-diphtheria toxin fragment which contains a cell binding portion. The modified diphtheria toxins described can be used for the treatment of a malignant disease or a non-malignant disease. | 01-08-2009 |
20090041797 | MODIFIED TOXINS - The present application relates to compositions of modified toxins exhibiting reduced immunogenicity and reduced binding to vascular endothelium or vascular endothelial cells, thereby reducing the incidence of Vascular Leak Syndrome. Also provided are polypeptide toxophores from a modified diphtheria toxin, where modifications are in at least one amino acid residue of at least one T-cell epitope. Another aspect relates to a polypeptide toxophore from a modified diphtheria toxin, where modifications are in at least one amino acid residue of at least one T-cell epitope and at least one amino acid residue of at least one VLS motif of an unmodified native diphtheria toxin. Another aspect relates to a fusion protein which comprises a modified diphtheria toxin and a non-diphtheria toxin fragment that is a cell binding portion. Another aspect relates to the use of a modified diphtheria toxin for the treatment of a malignant disease or a non-malignant disease. | 02-12-2009 |
20090221500 | MODIFIED TOXINS - The present application relates to compositions of modified toxins exhibiting reduced immunogenicity and reduced binding to vascular endothelium or vascular endothelial cells, thereby reducing the incidence of Vascular Leak Syndrome. Also provided are polypeptide toxophores from a modified diphtheria toxin, where modifications are in at least one amino acid residue of at least one T-cell epitope. Another aspect relates to a polypeptide toxophore from a modified diphtheria toxin, where modifications are in at least one amino acid residue of at least one T-cell epitope and at least one amino acid residue of at least one VLS motif of an unmodified native diphtheria toxin. Another aspect relates to a fusion protein which comprises a modified diphtheria toxin and a non-diphtheria toxin fragment that is a cell binding portion. Another aspect relates to the use of a modified diphtheria toxin for the treatment of a malignant disease or a non-malignant disease. | 09-03-2009 |
Patent application number | Description | Published |
20090237297 | Geodesy Via GPS and INSAR Integration - A method for representing surface deformation measurements, including providing InSAR data, wherein the InSAR data is line of sight InSAR data; providing Global Positioning System (GPS) data; filtering the InSAR data; assembling the GPS data over a time span; resolving the GPS data into a line of sight direction; determining a correction; generating a corrected line of sight image; generating a plurality of XY motion maps, wherein generating includes: correlating a plurality of XY motions from a plurality of GPS sites with a gradient of the corrected line of site image; determining a correlation coefficient; and building a plane of XY motion using at least one of the plurality of XY motions; using the correlation coefficient to produce a linear combination of the plurality of XY motion maps; and using the linear combination to convert the InSAR data to vertical motion. | 09-24-2009 |
20090271115 | WELLBORE TRACKING - Wellbore tracking by developing a wellbore deviation survey, including collecting wellbore deformation data using a caliper at each of a plurality of depths within the wellbore, collecting wellbore deviation data using a tiltmeter at ones of the plurality of depths, determining simulated wellbore deformation and deviation data using the oriented wellbore deformation data, and developing a wellbore deviation survey by calibrating the wellbore deviation data based on the oriented wellbore deviation data. | 10-29-2009 |
20110141846 | MICROSEISMIC FRACTURE MAPPING USING SEISMIC SOURCE TIMING MEASUREMENTS FOR VELOCITY CALIBRATION - A system and method for micro seismic fracture mapping using seismic source timing measurements for velocity calibration ( | 06-16-2011 |
20120018167 | MAXIMIZING HYDROCARBON PRODUCTION WHILE CONTROLLING PHASE BEHAVIOR OR PRECIPITATION OF RESERVOIR IMPAIRING LIQUIDS OR SOLIDS - A method of flowing fluid from a formation, the method comprising: sensing presence of a reservoir impairing substance in the fluid flowed from the formation; and automatically controlling operation of at least one flow control device in response to the sensing of the presence of the substance. A well system, comprising: at least one sensor which senses whether a reservoir impairing substance is present; and at least one flow control device which regulates flow of a fluid from a formation in response to indications provided by the sensor. | 01-26-2012 |
Patent application number | Description | Published |
20080215290 | Determining a location based advertising campaign - A method of determining a location based advertising campaign is disclosed. A specification of location based advertising campaign characteristics is received. Available spots in an advertising supply are scored based on the specification. Selected spots are automatically determined from among the available spots in physical locations to include in the location based advertising campaign, based on an advertising budget and the scoring of the available spots. A description of the location based advertising campaign for displaying the selected spots is outputted. | 09-04-2008 |
20080215421 | Distributing a location based advertising campaign - A method for distributing a location based advertising campaign to a plurality of location based advertising networks is disclosed. A proposed location based advertising creative is received for approval. The proposed location based advertising creative is automatically distributed. Responses from the plurality of location based advertising networks are monitored. The proposed location based advertising creative is determined to have become an approved location based advertising creative. The approved location based advertising creative is automatically distributed to the plurality of location based advertising networks for execution of the location based advertising campaign. | 09-04-2008 |
20080215422 | Coordinating a location based advertising campaign - A method of automatically assigning a set of privileges to a team member in a distribution of location based advertising is disclosed. A process for the distribution of location based advertising is defined, wherein the process includes at least a client portion of the process, a media agency portion of the process, a buying service portion of the process and a creative agency portion of the process. A set of privileges associated with a portion of the process for the distribution of location based advertising is defined. A team member associated with the portion of the process for the distribution of location based advertising is defined. The set of privileges associated with the portion of the process for the distribution of location based advertising is automatically assigned to the team member associated with the portion of the process for the distribution of location based advertising. | 09-04-2008 |
20080270238 | Measuring a location based advertising campaign - A method of measuring a location based advertising campaign is disclosed. The location based advertising campaign is determined to have a direct response component. A response address associated with the direct response component is received. The location based advertising campaign with the direct response component is distributed to a location based advertising network. The location based advertising campaign is measured based on the response address's action statistics. | 10-30-2008 |
Patent application number | Description | Published |
20100329880 | HYBRID COMPOSITE FOR EROSION RESISTANT HELICOPTER BLADES - A protective hybrid composite for a rotor blade is based on the use of tape cast ceramic layers densified by pre-ceramic polymer infiltration methods and laminated together with polymer matrix composite prepregs, with or without an embedded metallic mesh, to form a conforming helicopter blade cladding that is laminated to the blade surface for added erosion protection. The hybrid composite is fabricated to net shape and laminated to the blade using either an adhesive or a polymer composite prepreg inner layer. Installation is accomplished by a standard composite fabrication method of vacuum bagging the blade while the system is laminated to its surface. Repair methods based on removal of ceramic tiles is facilitated by incorporation of a metallic mesh element laminated beneath the ceramic tiles that can be used to heat the tile and decrease its adhesion strength. | 12-30-2010 |
20140014263 | HYBRID COMPOSITE FOR EROSION RESISTANT HELICOPTER BLADES - A protective hybrid composite for a rotor blade is based on the use of tape cast ceramic layers densified by pre-ceramic polymer infiltration methods and laminated together with polymer matrix composite prepregs, with or without an embedded metallic mesh, to form a conforming helicopter blade cladding that is laminated to the blade surface for added erosion protection. The hybrid composite is fabricated to net shape and laminated to the blade using either an adhesive or a polymer composite prepreg inner layer. Installation is accomplished by a standard composite fabrication method of vacuum bagging the blade while the system is laminated to its surface. Repair methods based on removal of ceramic tiles is facilitated by incorporation of a metallic mesh element laminated beneath the ceramic tiles that can be used to heat the tile and decrease its adhesion strength. | 01-16-2014 |
20140065292 | USE OF MONAZITE OR XENOTIME SOLUTION PRECURSORS TO INCREASE THE DENSITY AND SHEAR STRENGTH OF OXIDE COMPOSITES - Aqueous precursor solutions are described that comprise at least one monazite-based material precursor, at least one xenotime-based material precursor or a combination thereof; and a plurality of fine suspended particles of an oxide material. Contemplated oxide composites, as described herein, comprise a plurality of fibers surrounded by at least one monazite or xenotime-based material, wherein the oxide composite has nearly a fully dense matrix. Contemplated embodiments disclosed herein provides a method for producing an oxide composite with nearly fully dense matrix and with all fibers surrounded by a monazite- or xenotime-based material that prevents embrittlement at temperatures at least as high as 1200° C. Oxide composites are described that contain a plurality of fibers, a matrix containing at least one or more oxide materials, and at least one monazite-based material, xenotime-based material or combination thereof, wherein the monazite-based or xenotime-based material is formed from the aqueous precursor solutions disclosed herein. Contemplated methods of production include: a) providing a composite comprising oxide-reinforcing fibers and a porous matrix of oxide materials, and b) infiltrating the porosity in the matrix with a solution that contains precursors for at least one monazite-based material, at least one xenotime-based material or a combination thereof; and c) heat treating the composite to convert the precursors to monazite, xenotime, or combinations thereof. | 03-06-2014 |
Patent application number | Description | Published |
20100280324 | Organ Manipulator Having Suction Member Supported with Freedom to Move Relative to Its Support - An organ manipulator including at least one suction member or adhesive disk mounted to a joint providing freedom of movement of the at least one suction member or adhesive disk relative to its support. A method for retracting and maintaining an organ in a retracted position using suction (or adhesive force) so that the organ is free to move normally (e.g., to beat or undergo other limited-amplitude motion) is provided. | 11-04-2010 |
20110288553 | METHOD AND DEVICES FOR TREATING SPINAL STENOSIS - Systems and methods for treating spinal stenosis include endoscopic access devices and bone removal devices used to perform a foraminotomy or other bone removal procedures. Some of the bone removal devices include expandable members which may be used to control the forced exerted and/or position of the bone removal mechanism, and to protect neurovascular structures and other soft tissue structures from the bone removal mechanism. Other bone removal devices include a trephine with a viewing window and a guide wire lumen used to position the trephine at a target tissue site using an anchored wire. The viewing window may be used to monitor structures or tissues adjacent to the target tissue site. | 11-24-2011 |
20120016192 | CANNULOTOME - Systems and methods for treating spinal stenosis include endoscopic access devices and bone removal devices used to perform a foraminotomy or other bone removal procedures. A bone removal device includes a cannulotome with an endoscopic imaging lumen. Optionally, an endoscope retaining device can be used to facilitate advancement of the endoscope through the cannulotome. | 01-19-2012 |
20120071714 | CANNULOTOME - Systems and methods for treating spinal stenosis include endoscopic access devices and bone removal devices used to perform a foraminotomy or other bone removal procedures. A bone removal device includes a cannulotome with an endoscopic imaging lumen. Optionally, an endoscope retaining device can be used to facilitate advancement of the endoscope through the cannulotome. | 03-22-2012 |
Patent application number | Description | Published |
20090150210 | Advertising associated with multimedia content - A method for placing advertisements selects a first content from a variety of content, analyzes the first content for the presence of advertiser references, and matches a first advertisement from an advertiser to the first content by using the advertiser references. This method determines a set of presentation preferences for presentation of the first advertisement in conjunction with the first content and includes the set of presentation preferences with the first content. In some cases, the method embeds the presentation preferences as advertising information into the first content. Advantageously, the method presents the first advertisement in conjunction with the first content by using the presentation preferences. Further, the method tracks the presentation of content for monetization events and stores the tracking information in a log. The monetization event includes, for example, an impression, a click, an acquisition, and/or a conversion. Further embodiments include a system and a computer readable medium for implementation of the foregoing. | 06-11-2009 |
20090157450 | ADPACK - A system for monetization of content includes a storage device for storage and retrieval of data, and a library of content and advertisements stored within the storage device. The library comprises an organizational structure for facilitating the storage and retrieval. The system also includes a monetization engine for identifying within the library a first content item having a first monetizable feature. The system is configured for selecting a second content item from several content items within the library, and associating the second content item to the first content item by using the first monetizable feature for presentation of the second content item in conjunction with the first content item. Further embodiments include various additional systems, methods, and computer readable media for implementation of the foregoing. | 06-18-2009 |
Patent application number | Description | Published |
20080198895 | SUBSTRATE TEMPERATURE MEASUREMENT BY INFRARED TRANSMISSION - A method and apparatus for measuring a substrate temperature during a thermal process are provided. In one embodiment, an apparatus for measuring a substrate temperature during a thermal process includes an evacutable chamber, a substrate heater positioned to heat a substrate disposed in the chamber, and a sensor positioned to receive energy transmitted through the substrate while the substrate is heated by the substrate heater, wherein the sensor is configured to detect a metric indicative of transmittance. In another embodiment, a method for measuring a substrate temperature includes heating a substrate disposed in a chamber, detecting a change in transmittance of the substrate while heating, and determining a temperature of the substrate based on the change in transmittance. | 08-21-2008 |
20090158265 | IMPLEMENTATION OF ADVANCED ENDPOINT FUNCTIONS WITHIN THIRD PARTY SOFTWARE BY USING A PLUG-IN APPROACH - Embodiments described herein generally relate to a method of updating a software routine with subprograms and subroutines that can be accessed by an end user on an as-needed basis. In one embodiment, a method of providing a control function for a semiconductor process to a pre-existing software architecture is described. The method includes providing a plug-in to the pre-existing software architecture, providing an upgrade library file having the control function therein, and uploading the upgrade library file to the pre-existing software architecture at the plug-in to facilitate process control of the semiconductor process. | 06-18-2009 |
20090218314 | ADVANCED PROCESS SENSING AND CONTROL USING NEAR INFRARED SPECTRAL REFLECTOMETRY - Embodiments described herein provide a method and apparatus for obtaining process information in a substrate manufacturing process using plasma. In one embodiment, a chamber is provided having one or more optical metrology modules that are positioned such that optical energy from the plasma process is detected at substantially orthogonal angles. Metrics derived from detected optical energy may be used for endpoint determination, substrate temperature, and monitoring of critical dimensions on the substrate. | 09-03-2009 |
20090316749 | SUBSTRATE TEMPERATURE MEASUREMENT BY INFRARED TRANSMISSION IN AN ETCH PROCESS - A method and apparatus for measuring a temperature during a process are provided. In one embodiment, an apparatus for measuring a substrate temperature during an etching process is provided that includes a chamber body, a chamber lid enclosing the chamber body and a substrate support assembly. A plurality of windows formed in a substrate supporting surface of the substrate support assembly. A signal generator is optically coupled through the substrate support assembly to the windows. A sensor is positioned above the substrate support and aligned to receive energy transmitted from the signal generator through at least one of the windows, wherein the sensor is configured to detect a metric indicative of transmittance. | 12-24-2009 |
Patent application number | Description | Published |
20090138015 | SPINAL IMPLANTS AND METHODS - Spinal implants are disclosed that can be used for annular repair, facet unloading, disc height preservation, disc decompression, or for sealing a portal through which an intervertebral implant was placed. In some embodiments, an implant is placed within the intervertebral disc space, primarily within the region of the annulus fibrosus. In some embodiments, the implant is expandable. In some embodiments, the implant has a sealing tail structure comprising a tail flange and a linkage. In some embodiments, the sealing tail structure limits the extrusion or expulsion of disc material, either annulus fibrosus or nucleus, into the posterior region of the spine where it could impinge on nerves. In some embodiments, the tail structure is retained in place within the annulus fibrosus by means of an anchor. In some embodiments, the anchor is constructed from multiple components. | 05-28-2009 |
20090138084 | SPINAL IMPLANTS AND METHODS - Spinal implants are disclosed that can be used for annular repair, facet unloading, disc height preservation, disc decompression, or for sealing a portal through which an intervertebral implant was placed. In some embodiments, an implant is placed within the intervertebral disc space, primarily within the region of the annulus fibrosus. In some embodiments, the implant is expandable. In some embodiments, the implant has a sealing tail structure comprising a tail flange and a linkage. In some embodiments, the sealing tail structure limits the extrusion or expulsion of disc material, either annulus fibrosus or nucleus, into the posterior region of the spine where it could impinge on nerves. In some embodiments, the tail structure is retained in place within the annulus fibrosus by means of an anchor. In some embodiments, the anchor is constructed from multiple components. | 05-28-2009 |
20090149959 | SPINAL IMPLANTS AND METHODS - Spinal implants are disclosed that can be used for annular repair, facet unloading, disc height preservation, disc decompression, or for sealing a portal through which an intervertebral implant was placed. In some embodiments, an implant is placed within the intervertebral disc space, primarily within the region of the annulus fibrosus. In some embodiments, the implant is expandable. In some embodiments, the implant has a sealing tail structure comprising a tail flange and a linkage. In some embodiments, the sealing tail structure limits the extrusion or expulsion of disc material, either annulus fibrosus or nucleus, into the posterior region of the spine where it could impinge on nerves. In some embodiments, the tail structure is retained in place within the annulus fibrosus by means of an anchor. In some embodiments, the anchor is constructed from multiple components. | 06-11-2009 |
20090171461 | SPINAL IMPLANTS AND METHODS - Spinal implants are disclosed that can be used for annular repair, facet unloading, disc height preservation, disc decompression, or for sealing a portal through which a nucleus an intervertebral implant was placed. In some embodiments, an implant is placed within the intervertebral disc space, primarily within the region of the annulus fibrosus. In some embodiments, the implant is expandable. In some embodiments, the implant has a sealing tail structure comprising a tail flange and a linkage. In some embodiments, the sealing tail structure limits the extrusion or expulsion of disc material, either annulus fibrosus or nucleus, into the posterior region of the spine where it could impinge on nerves. In some embodiments, the tail structure is retained in place within the annulus fibrosus by means of an anchor. In some embodiments, the anchor is constructed from multiple components. | 07-02-2009 |
20090270989 | SPINAL IMPLANTS AND METHODS - Spinal implants are disclosed that can be used for annular repair, facet unloading, disc height preservation, disc decompression, or for sealing a portal through which a nucleus implant was placed. In some embodiments, an implant is placed within the intervertebral disc space, primarily within the region of the annulus fibrosus. In some embodiments, the implant is expandable. In some embodiments, the implant has a sealing tail structure comprising a tail flange and a linkage. In some embodiments, the sealing tail structure limits the extrusion or expulsion of disc material, either annulus fibrosus or nucleus, into the posterior region of the spine where it could impinge on nerves. In some embodiments, the tail structure is retained in place within the annulus fibrosus by means of an anchor. In some embodiments, the anchor is constructed from multiple components. | 10-29-2009 |
20110245802 | OCCLUSION CATHETER HAVING COMPLIANT BALLOON FOR USE WITH COMPLEX VASCULATURE - A catheter used for treatment of complex vasculature, such as a bifurcated aneurysm, is provided with an inflatable balloon at a distal portion thereof. The shape, location and material of the inflatable balloon are selected such that when inflated, the balloon conforms to the shape of the complex vasculature, or at least a portion thereof, without appreciably deforming the vessel walls. In this manner, the balloon can be used to control flow in the vasculature, for example occluding a selected branch of the vasculature during introduction of material in order concentrate the material and minimize its disbursement by blood flow. | 10-06-2011 |
20130281836 | OCCLUSION CATHETER HAVING COMPLIANT BALLOON FOR USE WITH COMPLEX VASCULATURE - A catheter used for treatment of complex vasculature, such as a bifurcated aneurysm, is provided with an inflatable balloon at a distal portion thereof. The shape, location and material of the inflatable balloon are selected such that when inflated, the balloon conforms to the shape of the complex vasculature, or at least a portion thereof, without appreciably deforming the vessel walls. In this manner, the balloon can be used to control flow in the vasculature, for example occluding a selected branch of the vasculature during introduction of material in order concentrate the material and minimize its disbursement by blood flow. | 10-24-2013 |
Patent application number | Description | Published |
20100291414 | Battery Thermal Management System - In certain embodiments, a battery thermal management system includes at least one battery, at least one thermoelectric device in thermal communication with the at least one battery, and a conduit comprising an inlet configured to allow a working fluid to enter and flow into the conduit and into thermal communication with the at least one thermoelectric device. The conduit further comprises an outlet configured to allow the working fluid to exit and flow from the conduit and away from being in thermal communication with the at least one thermoelectric device. The battery thermal management system can further include a first flow control device which directs the working fluid through the inlet of the conduit and a second flow control device which directs the working fluid through the outlet of the conduit. The first flow control device and the second flow control device are each separately operable from one another. | 11-18-2010 |
20110236731 | Battery Thermal Management System - In certain embodiments, a battery thermal management system includes at least one battery, at least one thermoelectric device in thermal communication with the at least one battery, and a conduit comprising an inlet configured to allow a working fluid to enter and flow into the conduit and into thermal communication with the at least one thermoelectric device. The conduit further comprises an outlet configured to allow the working fluid to exit and flow from the conduit and away from being in thermal communication with the at least one thermoelectric device. The battery thermal management system can further include a first flow control device which directs the working fluid through the inlet of the conduit and a second flow control device which directs the working fluid through the outlet of the conduit. The first flow control device and the second flow control device are each separately operable from one another. | 09-29-2011 |
20120285758 | THERMOELECTRIC-BASED THERMAL MANAGEMENT SYSTEMS - In certain embodiments, a battery thermal management system includes at least one battery, at least one thermoelectric device in thermal communication with the at least one battery, and a conduit comprising an inlet configured to allow a working fluid to enter and flow into the conduit and into thermal communication with the at least one thermoelectric device. The conduit further comprises an outlet configured to allow the working fluid to exit and flow from the conduit and away from being in thermal communication with the at least one thermoelectric device. The battery thermal management system can further include a first flow control device which directs the working fluid through the inlet of the conduit and a second flow control device which directs the working fluid through the outlet of the conduit. The first flow control device and the second flow control device are each separately operable from one another. | 11-15-2012 |
Patent application number | Description | Published |
20090265750 | TECHNIQUES AND SYSTEMS FOR SUPPORTING PODCASTING - Improved podcasts and techniques that facilitate their use are disclosed. The improved techniques can pertain to creating, publishing, hosting, accessing, subscribing, managing, transferring, and/or playing podcasts. According to one aspect, a client application can subscribe to podcasts and then automatically monitor the podcasts for updates to be downloaded. In the event that user interest in a podcast becomes inadequate, downloading of further updates can be restricted. According to another aspect, a podcast can be subscribed to through use of a portable subscription file. According to still another aspect, podcast feeds can be enhanced to include segment elements and other metadata. | 10-22-2009 |
20120011227 | TECHNIQUES AND SYSTEMS FOR SUPPORTING PODCASTING - Improved podcasts and techniques that facilitate their use are disclosed. The improved techniques can pertain to creating, publishing, hosting, accessing, subscribing, managing, transferring, and/or playing podcasts. According to one aspect, a client application can subscribe to podcasts and then automatically monitor the podcasts for updates to be downloaded. In the event that user interest in a podcast becomes inadequate, downloading of further updates can be restricted. According to another aspect, a podcast can be subscribed to through use of a portable subscription file. According to still another aspect, podcast feeds can be enhanced to include segment elements and other metadata. | 01-12-2012 |
20120284422 | TECHNIQUES AND SYSTEMS FOR SUPPORTING PODCASTING - Improved podcasts and techniques that facilitate their use are disclosed. The improved techniques can pertain to creating, publishing, hosting, accessing, subscribing, managing, transferring, and/or playing podcasts. According to one aspect, a client application can subscribe to podcasts and then automatically monitor the podcasts for updates to be downloaded. In the event that user interest in a podcast becomes inadequate, downloading of further updates can be restricted. According to another aspect, a podcast can be subscribed to through use of a portable subscription file. According to still another aspect, podcast feeds can be enhanced to include segment elements and other metadata. | 11-08-2012 |
20140026049 | Techniques and Systems for Supporting Podcasting - Improved podcasts and techniques that facilitate their use are disclosed. The improved techniques can pertain to creating, publishing, hosting, accessing, subscribing, managing, transferring, and/or playing podcasts. According to one aspect, a client application can subscribe to podcasts and then automatically monitor the podcasts for updates to be downloaded. In the event that user interest in a podcast becomes inadequate, downloading of further updates can be restricted. According to another aspect, a podcast can be subscribed to through use of a portable subscription file. According to still another aspect, podcast feeds can be enhanced to include segment elements and other metadata. | 01-23-2014 |
Patent application number | Description | Published |
20100286554 | NEUROLOGIC MONITORING SYSTEM AND METHOD - A method, system, and products that allow for accurate localization, virtual depiction, and testing of nerve(s) or neural structures that course through or around a proposed surgical site are described. The method and system employs a variety of types of neurodiagnostic tests that incorporate sensory, motor, and mixed nerve conduction studies in an orthodromic and antidromic fashion as well as utilizing triggered electromyography. This method, system, and products allow for a much more specific and sensitive method to assess the baseline function and continued integrity of nerves and neural structures prior to, during, and after a surgical procedure. | 11-11-2010 |
20120296230 | NEUROLOGIC MONITORING SYSTEM AND METHOD - A method, system, and products that allow for accurate localization, virtual depiction, and testing of nerve(s) or neural structures that course through or around a proposed surgical site are described. The method and system employs a variety of types of neurodiagnostic tests that incorporate sensory, motor, and mixed nerve conduction studies in an orthodromic and antidromic fashion as well as utilizing triggered electromyography. This method, system, and products allow for a much more specific and sensitive method to assess the baseline function and continued integrity of nerves and neural structures prior to, during, and after a surgical procedure. | 11-22-2012 |