Brookes
Anthony Joseph Brookes, Leicester GB
Patent application number | Description | Published |
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20100184153 | High Multiplex Nucleic Acid Amplification - This invention relates to the amplification of multiple nucleic acid target sequences. Forward and reverse compound primers comprising a common amplification sequence and a target-specific primer sequence are immobilised at a site on a solid support. Target regions of single-stranded template DNA are primed and copied by the forward primer to produce a first extension product. The template DNA is removed and the first extension product is primed and copied by the reverse primer to produce a second extension product. The second extension product has common amplification sequences at each end and is bulk-amplified in solution by regular PCR employing primers that target the common amplification sequences. These methods allow highly multiplexed amplifications to be performed. | 07-22-2010 |
Chisa K. Brookes, Houston, TX US
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20130025873 | Protecting A Fluid Stream From Fouling - Embodiments described herein provide a system and methods for protecting a fluid stream from fouling using particles that include phase change materials. In an example, the particles are injected into the fluid stream and release energy at a selected temperature, which may warm the fluid stream. | 01-31-2013 |
Christopher John Brookes, Richmond CA
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20110012858 | DUAL SCREEN DISPLAY SYSTEM - A display system is provided with a first display device having a first screen and a second display device having a second screen. The display system also includes a hinging system connecting the first display device and the second display device. The hinging system is configured to permit the second display device to rotate independently of the first display device. | 01-20-2011 |
David Brookes, Derby GB
Patent application number | Description | Published |
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20160118176 | SURFACE MOUNTABLE, TOROID MAGNETIC DEVICE - A surface mountable, toroid magnetic device is provided, the device having a potting filling the central hole of the toroid. The potting extends axially beyond the base of the toroid to form a contact surface which, in use, contacts a mounting body for the device. Heat generated by the device flows by conduction through walls of the toroid defining the central hole into the potting and thence through the contact surface into the mounting body. | 04-28-2016 |
David Brookes, Mississauga CA
Patent application number | Description | Published |
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20080308017 | Dual Chamber System for Gasifying Biomass Waste - A device for gasifying biomass waste has two each of primary chambers, fume transfer vents, mixing chambers which accept fumes from the primary chamber, afterburner chambers in fluid communication with the mixing chambers, and an exhaust duct. Each secondary burner produces an initial heating flame within a vertical portion of the respective afterburner chamber, and secondary chambers are in fluid communication with the afterburner chambers. Heated gases from the afterburner chambers cause heating of the secondary chambers. A portion of each primary chamber has a heat conductive floor superimposed over the respective secondary chamber, and the partition between the primary chambers is heat conductive, so that conductive and convective heating of the primary chambers occurs. | 12-18-2008 |
David Brookes, Houston, TX US
Patent application number | Description | Published |
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20150331127 | METHODS AND SYSTEMS FOR CONDUCTING RECONNAISSANCE MARINE SEISMIC SURVEYS - Methods, systems, and apparatuses are disclosed for conducting reconnaissance marine seismic surveys. In one example method of acquiring a marine seismic survey, a plurality of streamers are towed behind an acquisition vessel, the plurality of streamers defining a swath. An independent source is towed by an independent source vessel above one or more of the plurality of towed streamers. | 11-19-2015 |
David Frederick Brookes, Birmingham GB
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20080291964 | Temperature Sensing - A TGT measurement system comprises a plurality of thermocouples connected in parallel to a distributor, and a data storage device carrying calibration data relating to at least one of the thermocouples. | 11-27-2008 |
David John Brookes, Sutton Coldfield GB
Patent application number | Description | Published |
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20100329811 | VARIABLE GRIP BLIND RIVET - A variable grip blind rivet includes a tubular rivet body and a mandrel. The rivet body has a first shank, insertable into a hole in a workpiece, and a flange at a first end of the first shank for abutting the workpiece when so inserted. The mandrel has a head, for engaging a second end of the first shank, and a second shank adapted to extend through the axial bore of the rivet body. The head has an abutment portion for abutting the first end of the first shank, and the second shank has a first reduced diameter portion adapted to break when a predetermined tensile is loaded applied. At least one protrusion adjacent the abutment portion defines a recess for receiving the first end of the first shank during setting of the rivet. | 12-30-2010 |
20130287516 | VARIABLE GRIP BLIND RIVET - A variable grip blind rivet has a rivet body with a first shank adapted to be inserted into a hole in a workpiece and having an axial bore, and a flange at a first end of the first shank for abutting the workpiece when the first shank is inserted into the hole in the workpiece. A mandrel has a head, for engaging a second end of the first shank, and a second shank adapted to extend through the axial bore. The head has an abutment portion for abutting the first end of the first shank. At least one protrusion adjacent the abutment portion defines a recess for receiving the first end of the first shank during setting of the rivet. | 10-31-2013 |
David Patrick Edward Brookes, Oxfordshire GB
Patent application number | Description | Published |
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20100206055 | Monitoring an Immunoassay - A method of monitoring an immunoassay comprises determining the position of the flow edge of fluid across an immunoassay region. This allows, for example, early detection of possible errors in the test. For example the speed of the movement of the fluid flow edge may be determined from measurements of the position of the fluid flow edge at times throughout the test, and the determined speed may be compared with one or more thresholds to determine whether the test is proceeding correctly. A further method of monitoring an immunoassay comprising monitoring the variation with time of a reference zone of an immunoassay region. This can provide the user with early information as to whether the test is proceeding correctly. The above methods may also be used to provide methods to improve the run conditions of a test during its development. The method may be applied to a competitive assay. | 08-19-2010 |
Graham Brookes, Noblesville, IN US
Patent application number | Description | Published |
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20150234689 | INTERFACE COMBINING MULTIPLE SYSTEMS INTO ONE - A vehicle system includes a vehicle, a vehicle control unit (VCU), a plurality of data modules and a data conversion interface. The vehicle includes a chassis that supports the other components of the vehicle, including the VCU. The data modules each provide an output signal with a data type specific to each data module. The data conversion interface couples with the VCU and each data module. The data conversion interface receives the output signal from each data module, converts each output signal into a common data format, and transmits the converted output signals to the VCU. | 08-20-2015 |
Graham R Brookes, Carmel, IN US
Patent application number | Description | Published |
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20080228352 | VEHICLE SUSPENSION SYSTEM AND METHOD OF OPERATING SAME - A suspension system for use on a vehicle having two or more rear axles. The suspension system includes a plurality of gas springs and plurality of height sensors capable of outputting signals having a relation to distances between the respective ends of the respective first and second rear axles and the sprung mass of the vehicle. A control system adapted to selectively inflate or deflate respective ones of the plurality of gas springs to thereby adjust a leveled orientation of the sprung mass. The control system includes a controller that is adapted to determine a rear axle vertical offset and a rear axle articulation offset. The controller is adapted to determine whether conditions are appropriate for adjusting the suspension system by comparing the rear axle vertical offset and/or the rear axle articulation offset to a corresponding vertical offset threshold and/or an articulation offset threshold. A method is also included. | 09-18-2008 |
20110115139 | GAS SPRING AND GAS DAMPER ASSEMBLY AND METHOD - A gas spring and gas clamper assembly includes a first end member, a second end member, a first flexible wall that at least partially defines a first spring chamber, and a second flexible wall that at least partially defines a second spring chamber. A damper piston and damper rod are operatively connected between the first and second end members and within the first spring chamber. A suspension system that includes a gas spring and gas damper assembly as well as a method of assembly are also included. | 05-19-2011 |
20120086178 | HEIGHT CONTROL MODULE, GAS SPRING ASSEMBLY AND METHOD - A gas spring assembly includes a gas spring and a height control module. The gas spring includes a first end member, a second end member and a flexible wall secured therebetween. The height control module includes a height control system that is operatively associated with the gas spring. The height control system includes a sensor, a valve arrangement and a fixed-logic control circuit. A suspension system and a method are also included. | 04-12-2012 |
20120200057 | PRIMARY AIR SPRING AND SECONDARY LEAF SUSPENSION FOR VEHICLE - A suspension for a vehicle having a chassis rail and a longitudinal axle arranged substantially orthogonal thereto. The vehicle suspension has a primary air-responsive spring that couples between the chassis and the axle of the vehicle. The primary spring can be a coil spring that surrounds an air helper spring. A secondary leaf spring has a first end for pivotally coupling to the chassis of the vehicle at a secondary pivot coupling, and a second end for coupling to the axle. The longitudinal configuration of the secondary leaf spring can be arranged to be angularly displaced with respect to a chassis rail of the vehicle. | 08-09-2012 |
20140035210 | FLEXIBLE SPRING MEMBER AS WELL AS GAS SPRING ASSEMBLY AND METHOD OF MANUFACTURE - Flexible spring members can be dimensioned for securement to an associated gas spring end member. The flexible spring member can be at least partially formed from elastomeric material. The flexible spring member can also include a marking disposed along a surface thereof that includes one or more indicia. The marking can be at least partially formed by an indicia layer and an outer layer. The indicia layer can include one or more quantities of material that at least partially form the one or more indicia. The outer layer can be formed from a quantity of material that is disposed overtop of the indicia layer such that the one or more indicia of the indicia layer are substantially encapsulated. Gas spring assemblies, suspension systems, methods of manufacture and manufacturing systems are also included. | 02-06-2014 |
20140091505 | END MEMBERS, GAS SPRING ASSEMBLIES AND SUSPENSION SYSTEMS - An end member for a gas spring assembly can include a first end, a second end opposite the first end and a plurality of reflector surfaces formed along the first end. A first reflector surface can extend from the first end toward the second end. A second reflector surface can extend from adjacent the first reflector surface toward the second end. One or more of the plurality of reflector surfaces can include a plurality of facets or reflector zones. A gas spring assembly including at least one of such end members and a suspension system including one or more of such gas spring assemblies are also disclosed. | 04-03-2014 |
20140155180 | TORSIONAL COUPLERS - A torsional coupler can be dimensioned for securement between a rotational motion source and a rotational motion target. The torsional coupler can include a first end component and a second end component that can cooperatively interengage one another such that such that rotational motion imparted on the first end component is transmitted to the second end component. Interposed between the first end component and the second end component is one or more force-transfer elements through which torque and/or other rotational output is transmitted. The one or more force-transfer elements can include one or more pressurizable elements into and out of which pressurized fluid (e.g., gas and/or liquid) can be transferred. Additionally, or in the alternative, the one or more force-transfer elements can include one or more biasing elements having a positive stiffness and one or more biasing elements having a negative stiffness. A rotary power transmission is also included. | 06-05-2014 |
20140299215 | PRESSURIZED GAS RESERVOIRS INCLUDING AN ELASTOMERIC WALL - A pressurizable gas reservoir can include a first end member and a second end member that is disposed in longitudinally-spaced relation to the first end member. A flexible reservoir member can extend between opposing first and second ends. The first end secured to the first end member and the second end secured to the second end member. The flexible reservoir member at least partially defines a reservoir chamber between the first and second end members that is capable of storing a quantity of pressurized gas for an extended duration of time. The first and second end members can be maintained in substantially-fixed axial position relative to one another. A suspension system including such a pressurized gas reservoir and a method of assembly are also included. | 10-09-2014 |
Graham R. Brookes, Noblesville, IN US
Patent application number | Description | Published |
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20140345450 | GAS SPRING END MEMBERS AS WELL AS GAS SPRING AND GAS DAMPER ASSEMBLIES INCLUDING SAME - A piston assembly including an integral piston chamber with an increased volume that is maximized by providing a mounting arrangement whereby the piston can be mounted to a structural member such that the piston chamber surrounds at least two sides of the structural member. A gas damping passage is disposed in fluid communication with the piston chamber and is dimensioned such that pressurized gas transferred through the gas damping passage can dissipate kinetic energy acting on the piston assembly. The piston chamber can therefore utilize space adjacent the structural member to which it is mounted thereby resulting in a piston chamber of a greater volume than prior art designs. A gas spring and gas damper assembly utilizing such a piston assembly is also included. | 11-27-2014 |
20140346749 | GAS SPRING AND GAS DAMPER ASSEMBLY AND METHOD - A gas spring and gas damper assembly includes a first end member, a second end member and a flexible wall that at least partially defines a first spring chamber therebetween. A damping chamber wall at least partially defines a damping chamber. A damper piston is received within the damping chamber and is operatively connected between the first and second end members and within the first spring chamber. A suspension system that includes a gas spring and gas damper assembly as well as a method of assembly are also included. | 11-27-2014 |
20150130146 | GAS SPRING AND GAS DAMPER ASSEMBLY - A gas spring and gas damper assembly ( | 05-14-2015 |
20160108984 | FLEXIBLE SPRING MEMBER AS WELL AS GAS SPRING ASSEMBLY AND METHOD OF MANUFACTURE - Flexible spring members can be dimensioned for securement to an associated gas spring end member. The flexible spring member can be at least partially formed from elastomeric material. The flexible spring member can also include a marking disposed along a surface thereof that includes one or more indicia. The marking can be at least partially formed by an indicia layer and an outer layer. The indicia layer can include one or more quantities of material that at least partially form the one or more indicia. The outer layer can be formed from a quantity of material that is disposed overtop of the indicia layer such that the one or more indicia of the indicia layer are substantially encapsulated. Gas spring assemblies, suspension systems, methods of manufacture and manufacturing systems are also included. | 04-21-2016 |
Jeremy R. Brookes, Lexington, KY US
Patent application number | Description | Published |
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20080223930 | CASH TRACKING SYSTEM - A system of tracking the location of cash is disclosed. | 09-18-2008 |
Kyle Brookes, Redwood City, CA US
Patent application number | Description | Published |
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20150244458 | Optical Communication Terminal - An optical communication terminal is configured to operate in two different complementary modes of full duplex communication. In one mode, the terminal transmits light having a first wavelength and receives light having a second wavelength along a common free space optical path. In the other mode, the terminal transmits light having the second wavelength and receives light having the first wavelength. The terminal includes a steering mirror that directs light to and from a dichroic element that creates different optical paths depending on wavelength, and also includes spatially separated emitters and detectors for the two wavelengths. A first complementary emitter/detector pair is used in one mode, and a second pair is used for the other mode. The optical components are arranged such that adjusting an orientation of the steering mirror aligns the terminal to communication over a given free space optical link using either the first or second complementary pair. | 08-27-2015 |
20150266560 | CUTTER RAIL GUIDE, BLOCK, ARMATURE, AND BLADE - An apparatus including a balloon envelope, a cutting blade secured to a blade block; a cutter guide rail secured above the balloon envelope, and an arm rotatable about a pivot point having an end secured to the blade block, wherein the end of the arm extends past the blade block, wherein the arm is releasably secured by a release member, and wherein release of the arm from the release member allows for a rotation of the arm, wherein the rotation of the end of the arm is guided by the cutter guide rail such that the cutting blade maintains contact with and cuts the balloon envelope during the rotation of the arm. | 09-24-2015 |
20150291270 | FILLING APPARATUS FOR HIGH-ALTITUDE BALLOONS - High-altitude balloons and apparatuses for filling such high-altitude balloons are provided. As an example, an apparatus for filling a high-altitude balloon includes a tube extending through envelope material of the balloon is provided. The apparatus also includes a flange connected to a first end of the tube. The flange is connected to an interior surface of the balloon. A fitting is connected to a second end of the tube. The fitting is configured for attachment with an apparatus for filling the balloon with lift gas. In addition, methods of filling high-altitude balloons with lift gas and methods of manufacturing balloons are also provided. | 10-15-2015 |
20160031543 | Cutter Rail Guide, Block, Armature, and Blade - An apparatus including a balloon envelope, a cutting blade secured to a blade block; a cutter guide rail secured above the balloon envelope, and an arm rotatable about a pivot point having an end secured to the blade block, wherein the end of the arm extends past the blade block, wherein the arm is releasably secured by a release member, and wherein release of the arm from the release member allows for a rotation of the arm, wherein the rotation of the end of the arm is guided by the cutter guide rail such that the cutting blade maintains contact with and cuts the balloon envelope during the rotation of the arm. | 02-04-2016 |
20160059951 | Uni-Penetration Tendon Retention and Fill Port System for a Balloon Envelope - Methods and apparatus are disclosed for an apex fitting for securing to a high altitude balloon. An example apparatus involves: (a) a base plate defining an opening, where the base plate is configured to be securable to an exterior of a balloon envelope, (b) at least one stud coupled to the base plate and configured to be securable to a tendon, (c) a retention ring defining at least one opening configured to receive the at least one stud, (d) a fill-port body defining a cavity, wherein a flange is coupled to the fill-port body, wherein the fill-port body is arranged coaxially with and extends through the opening of the base plate such that the flange lies adjacent to the bottom surface of the base plate, and (e) a locking body coupled to the fill-port body, wherein the locking body defines an opening arranged coaxially with the fill-port body. | 03-03-2016 |
Lawrence D. Brookes, Washington, NJ US
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20140048500 | SHELVING SYSTEM - Shelving systems having repositionable shelves are described herein. A locking mechanism releasably secures cleats at predetermined positions relative to supports. The cleats disclosed herein are configured and adapted to support different objects including shelves and/or elongated objects, e.g., bars that are configured and adapted to support bottles thereon. | 02-20-2014 |
Matthew Brookes, Salisbury, Wiltshire GB
Matthew Brookes, Chelmsford GB
Patent application number | Description | Published |
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20140028287 | CURRENT TRANSFORMER - A current transformer is described which comprises a housing having one or more apertures, each for receiving a primary cable or busbar, one or more magnetic cores enclosed within the housing and being positioned proximate to respective ones of the apertures so that a magnetic field is produced in a magnetic core when a primary current flows through a primary cable or busbar received through the respective aperture, and one or more secondary windings enclosed within the housing, each secondary winding being wrapped around at least a portion of a respective magnetic core so that a secondary current is induced in a secondary winding when a magnetic field is produced in the respective magnetic core. Shunt circuitry is enclosed within the housing and is connected across the secondary windings to generate a respective voltage signal for each secondary winding. A connector socket is integrally mounted to the housing for outputting the voltage signals. In this way, the labour costs incurred during installation of the current transformer can be reduced, a risk of wiring errors can be avoided, and a risk of electrocution from secondary terminals being left open-circuit is removed. | 01-30-2014 |
Michael J. Brookes, Brielle, NJ US
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20120209633 | METHOD OF PROVIDING INSURANCE INFORMATION - A method of providing insurance on one or more objects owned by the same or different owners and having object information related to the objects in a database maintained by a party for a purpose independent of providing insurance, including creating object insurance information from the object information in the database for one or more of the objects, electronically transferring the object insurance information on one or more of the objects to a carrier capable of providing insurance quotes and coverage, generating an insurance quote for one or more of the objects, the insurance quote being based at least in part on the object insurance information submitted, and presenting the quote to an owner of an object for acceptance. The method may include providing the owner with the quote electronically and including a link to bind coverage, with payments arranged automatically on a regular schedule. | 08-16-2012 |
20140244316 | METHOD OF QUOTING INSURANCE - A method of quoting insurance on one or more objects, the objects being owned by the same or different owners and having object information related to the objects in a database maintained by a party for a purpose independent of providing insurance, including electronically accessing object insurance information having been previously entered by an owner of one or more objects for a purpose other than obtaining insurance, electronically transferring the object insurance information to a carrier, generating an insurance quote based at least in part on the object insurance information, and presenting the quote to an owner of an object for acceptance. The method further contemplates providing the owner with the quote electronically and including a link to bind coverage, with payments that can be arranged automatically on a regular schedule. | 08-28-2014 |
Paul Brookes, Worcestershire GB
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20110219538 | Support Means for a Patient Handling Hoist - A support device for a patient handling hoist includes two opposed support arms for supporting a harness, each support arm having a harness engagement element. Each support arm is movable between a first working position in which the harness engagement element is a first distance from a central portion of the support device and a plurality of further working positions in which the harness engagement elements of the support arms are a respective plurality of distances from the central portion of the support device. | 09-15-2011 |
Paul C. Brookes, Acton, MA US
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20160079551 | PLANARIZATION LAYER FOR ORGANIC ELECTRONIC DEVICES - The invention relates to organic electronic devices containing polycycloolefin planarization layers between the substrate and a functional layer such as a semiconducting layer, dielectric layer, or electrode; to the use of polycycloolefins as a planarization layer on the substrate of an organic electronic device; and to processes for preparing such polycycloolefin planarization layers and organic electronic devices. | 03-17-2016 |
Paul Craig Brookes, Southampton GB
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20110021037 | COMPOSITION FOR MANUFACTURING SIO2 RESIST LAYERS AND METHOD OF ITS USE - The present invention relates to compositions, which are useful for the generation of patterned or structured SiO | 01-27-2011 |
20110227055 | PROCESS FOR THE PREPARATION OF ORGANIC ELECTRONIC DEVICES - The invention relates to the use of a closed field unbalanced magnetron sputter ion plating process in the preparation of organic electronic devices or components thereof, and to organic electronic devices, or components thereof, obtainable by such a process. | 09-22-2011 |
20120153285 | SOLUTION PROCESSABLE PASSIVATION LAYERS FOR ORGANIC ELECTRONIC DEVICES - The present invention relates to solution processable passivation layers for organic electronic (OE) devices, and to OE devices, in particular organic field effect transistors (OFETs), comprising such passivation layers. | 06-21-2012 |
20120319097 | ELECTRODE TREATMENT PROCESS FOR ORGANIC ELECTRONIC DEVICES - The present invention relates to a process for the treatment of electrodes in organic electronic (OE) devices, in particular organic field effect transistors (OFETs), to devices prepared by such a process, and to materials and formulations used in such a process. | 12-20-2012 |
20130069020 | FORMULATION AND METHOD FOR PREPARATION OF ORGANIC ELECTRONIC DEVICES - The present invention relates to novel formulations comprising an organic semiconductor (OSC) and one or more organic solvents. The formulation comprises a viscosity at 25° C. of less than 15 mPas and the boiling point of the solvent is at most 400° C. Furthermore, the present invention describes the use of these formulations as inks for the preparation of organic electronic (OE) devices, especially organic photovoltaic (OPV) cells and OLED devices, to methods for preparing OE devices using the novel formulations, and to OE devices, OLED devices and OPV cells prepared from such methods and formulations. | 03-21-2013 |
20130207091 | PLANARIZATION LAYER FOR ORGANIC ELECTRONIC DEVICES - The invention relates to organic electronic devices containing polycycloolefin planarization layers between the substrate and a functional layer like a semiconducting layer, dielectric layer or electrode, to the use of polycycloolefins as planarization layer on the substrate of an organic electronic device, and to processes for preparing such polycycloolefin planarization layers and organic electronic devices. | 08-15-2013 |
Paul Craig Brookes, Acton, MA US
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20150243914 | ORGANIC SEMICONDUCTOR FORMULATIONS - Embodiments in accordance with the present invention relate generally to formulations for use in organic semiconductor layers of organic electronic devices, and more specifically in organic field effect transistors, to organic semiconductor layers prepared from such formulations, and to organic electronic devices and organic field effect transistors encompassing such organic semiconductor layers. | 08-27-2015 |
20150280128 | PASSIVATION LAYERS FOR ORGANIC ELECTRONIC DEVICES - The invention generally relates to passivation layers for use in organic electronic devices, and more specifically in organic field effect transistors, to processes for preparing such passivation layers, and to organic electronic devices and organic field effect transistors encompassing such passivation layers. | 10-01-2015 |
Paul S. Brookes, Rochester, NY US
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20090149540 | Compositions and Methods for Attenuating Mitochondria-Mediated Cell Injury - The present invention relates to a S-nitrosated mitochondria-targeted thiol-based antioxidant prodrug and uses therefore for the prevention or treatment of diseases or conditions associated with mitochondrial dysfunction resulting from changes in the mitochondrial redox environment. When activated, prodrug of the present invention can specifically provide a NO* donor and a thiol-based antioxidant to mitochondria thereby decreasing the degree of mitochondrial dysfunction. | 06-11-2009 |
Paul Spencer Brookes, Rochester, NY US
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20100168198 | Mitochondria-targeted antioxidant prodrugs and methods of use - The present invention is a mitochondria-targeted antioxidant prodrug useful for the prevention or treatment of diseases or conditions associated with mitochondrial dysfunction resulting from changes in the mitochondrial redox environment. Antioxidant prodrugs of the invention are produced by modifying an antioxidant to a fatty acid so that the resulting prodrug is targeted to and activated by an enzyme of mitochondrial fatty acid beta-oxidation. | 07-01-2010 |
Philip Brookes, Hertfordshire GB
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20120183354 | METHOD OF REDUCING NITRATE LEACHING FROM SOIL - This invention relates to uses of waste products obtained when biodiesel is generated for reducing nitrate leaching from soil. | 07-19-2012 |
Roger Brookes, Toronto CA
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20100297133 | Immunogenic Polypeptides and Monoclonal Antibodies - Provided herein are compositions and methods for eliciting an immune response against | 11-25-2010 |
20110130300 | ASSAY FOR DIAGNOSING STREPTOCOCCUS PNEUMONIAE - Assays for detecting anti-streptococcal antibodies in biological samples using one or more streptococcal antigens are described herein. Various combinations of antigens may be used in the assays. For example, one or more of Ply, PhtD, PhtE, LytB and PcpA may be utilized. Additional streptococcal antigens may also be used. The assays may also be used in combination with assays that detect streptococcal nucleic acids. | 06-02-2011 |
20140349863 | Assay for Diagnosing Streptococcus Pneumoniae - Assays for detecting anti-streptococcal antibodies in biological samples using one or more streptococcal antigens are described herein. Various combinations of antigens may be used in the assays. For example, one or more of Ply, PhtD, PhtE, LytB and PcpA may be utilized. Additional streptococcal antigens may also be used. The assays may also be used in combination with assays that detect streptococcal nucleic acids. | 11-27-2014 |
20150316567 | METHODS FOR ASSESSING IMMUNOGENICITY - This disclosure relates to methods for detecting the potency of a drug preparation and/or detecting antibodies in a host reactive against one or more antigens. | 11-05-2015 |
Roger Hamilton Brookes, Toronto CA
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20140087399 | ASSAY METHOD FOR PEPTIDE SPECIFIC T-CELLS - A method of assaying for peptide-specific T-cells comprises adding peptide to a fluid sample of fresh peripheral blood mononuclear cells, and detecting a cytokine such as interferon-y produced by T-cells that have been pre-sensitised to the peptide. The assay method is quick and cheap and is expected to be useful for the study of various disease states including Hepatitis B, Hepatitis C, tuberculosis, malaria, HIV and influenza. | 03-27-2014 |
Roger Hamilton Brookes, Toronto GB
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20100203568 | Assay Method For Peptide Specific T-Cells - A method of assaying for peptide-specific T-cells comprises adding peptide to a fluid sample of fresh peripheral blood mononuclear cells, and detecting a cytokine such as interferon-γ produced by T-cells that have been pre-sensitised to the peptide. The assay method is quick and cheap and is expected to be useful for the study of various disease states including Hepatitis B, Hepatitis C, tuberculosis, malaria, HIV and influenza. | 08-12-2010 |
Stephan Peter Brookes, Berlin DE
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20150177169 | TEST SYSTEM AND TEST METHOD - The invention relates to a test system for cooling and/or heating at least one test piece comprising a platform, at least one heating and/or cooling fluid providing means coupled to the platform, at least one position means for reproducibly fixing the relative position of the fluid providing means to the at least one test piece and wherein the at least one position means is connected to the platform, the platform comprising at least one fastening means, in particular two openings for releasable coupling the fluid providing means for an at least temporarily fixing of the relative position of the fluid proving means to the test piece. It also relates to a test method. | 06-25-2015 |
Stephen John Brookes, Durham GB
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20150234057 | PHOTOMULTIPLIER APPARATUS AND RADIATION DETECTOR INCORPORATING SUCH APPARATUS - A radiation detection apparatus ( | 08-20-2015 |
Steven Brookes, Mississauga CA
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20110104114 | Polysaccharide-Protein Conjugates Reversibly Coupled Via Imine Bonds - A method of preparing an oxidised polysaccharide-protein conjugate by oxidising a polysaccharide with an oxidising agent to form an oxidised polysaccharide and combining such oxidized polysaccharide with a protein. The oxidised polysaccharide is reacted with a protein to form a composition comprising a conjugate wherein the oxidised polysaccharide and the protein are conjugated via one or more imine bonds and wherein the oxidised polysaccharide comprises essentially no alpha-hydroxy aldehyde units. The conjugate may be used to provide sustained or latent activity of the protein. | 05-05-2011 |
Steven J. Brookes, Thetford GB
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20110276315 | System and Method for Identifying Under-Defined Geometries Due to Singular Constraint Schemes - Systems, methods, and computer program products for identifying under-defined geometries due to singular constraint schemes. A method includes receiving a CAD model having a plurality of geometries and determining the degrees of freedom for each of the geometries. The method includes identifying a number of constraints on each of the geometries and identifying any of the geometries that are under-defined and any of the geometries that are well-defined. The method includes identifying any of the under-defined geometries that are under-defined due to singular (UDS) and storing a UDS indicator for each of the geometries identified as UDS. The method can include identifying geometries computed from these UDS geometries (CFS) and storing a CFS indicator for each of the geometries identified as CFS. | 11-10-2011 |
Tom Meredydd Brookes, Devon GB
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20090299635 | Terrain mapping - A terrain mapping apparatus ( | 12-03-2009 |