Soloman
David L. Soloman, Boston, MA US
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20130131041 | SPIROCYCLIC COMPOUNDS - The present invention relates to a novel class of substituted spirocyclic compounds. These compounds can inhibit histone deacetylase and are suitable for use in selectively inducing terminal differentiation, and arresting cell growth and/or apoptosis of neoplastic cells, thereby inhibiting proliferation of such cells. Thus, the compounds of the present invention are useful in treating a patient having a tumor characterized by proliferation of neoplastic cells. The compounds of the invention may also be useful in the prevention and treatment of TRX-mediated diseases, such as autoimmune, allergic and inflammatory diseases, and in the prevention and/or treatment of diseases of the central nervous system (CNS), such as neurodegenerative diseases. The present invention further provides pharmaceutical compositions comprising the compounds of the instant invention and safe dosing regimens of these pharmaceutical compositions, which are easy to follow, and which result in a therapeutically effective amount of these compounds in vivo. | 05-23-2013 |
Gary Soloman, Wilmington, NC US
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20140012779 | COMMUNICATION AND PROCESSING SYSTEM FOR DERIVATIVE - A method of facilitating trades of mismatch swaps including receiving trade data characterization a plurality of swap trades. Mismatches in at least two of the swap trades are identified and the mismatches are communicated to a plurality of traders. Offsetting mismatches may be identified and communicated to the plurality of traders also. The method may also include receiving offsetting mismatch trade requests from traders and communicating the offsetting mismatch trade requests to a clearinghouse. Identifying the offsetting mismatches may include determining a date gap between standard tenor instruments. And, the method may include determining whether the date gap is within a range of dates selected by a trader. The date gap will likely, in this instance, not be a benchmark tenor. | 01-09-2014 |
20150242950 | COMMUNICATION AND PROCESSING SYSTEM FOR DERIVATIVE OFFSETS - A method of facilitating trades of mismatch swaps including receiving trade data characterization a plurality of swap trades. Mismatches in at least two of the swap trades are identified and the mismatches are communicated to a plurality of traders. Offsetting mismatches may be identified and communicated to the plurality of traders also. The method may also include receiving offsetting mismatch trade requests from traders and communicating the offsetting mismatch trade requests to a clearinghouse. Identifying the offsetting mismatches may include determining a date gap between standard tenor instruments. And, the method may include determining whether the date gap is within a range of dates selected by a trader. The date gap will likely, in this instance, not be a benchmark tenor. | 08-27-2015 |
Houman Soloman, Hermosa Beach, CA US
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20160022402 | METHOD AND APPARATUS FOR SELF-ADHESIVE MEDICAL MESH DEPLOYMENT - Mesh for laparoscopic surgery includes, in addition to self-attaching mesh, a carrier or control layer used during insertion and alignment to reduce unwanted self-attachment to tissue in or outside of the target area to be repaired. The carrier has a control surface to which the self-attaching surface of the mesh does not attach and a tissue contact surface which has limited if any attachment to tissue. The mesh and carrier may be combined to form a layered mesh insertable during limited access surgery after which the carrier may be removed by trocar. The carrier may allow a limited portion of the working mesh surface to contact tissue in the cavity and thereby improve manipulation of the mesh within the cavity and re-alignable, pre-alignment of the mesh with the target area. The carrier includes tabs for maintaining alignment with the mesh in the cavity and for gripping to realign or remove the carrier from the cavity. The carrier may be in the form of paper, plastic and/or in an envelope configuration. | 01-28-2016 |
Sabrie Soloman, Daddle River, NJ US
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20100175352 | AUTOMATED PHARMACEUTICAL PRODUCT PACKAGING, INSPECTION, VERIFICATION, AND COUNTING APPARATUS - The present invention is an automated packaging apparatus utilizing a rotating assembly of elongated slats containing cavities to receive discrete pharmaceutical, vitamin, or food products. Quantities of discrete products such as tablets, capsules, or gels are deposited into the hopper of the apparatus. The apparatus then dispenses the discrete products into containers moving on a conveyor system such that each container receives a predetermined quality and quantity of pharmaceutical, vitamin, or food products. While operating at high speed, the apparatus inspects, counts, identifies and analyzes each product deposited into the containers and maintains electronic records describing the status of each product. In the event any errors occur the apparatus produces various alerts to inform the operator. The presence of foreign products or objects may cause the apparatus to instantly stop the entire system including peripheral equipment. A series of Good Manufacturing Practice protocols can then be enforced as per FDA requirements. | 07-15-2010 |
Sabrie Soloman, Saddle River, NJ US
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20120024806 | Segmented Slat - A slat segment is disclosed for use in packaging machines which dispense discrete pharmaceuticals, vitamin, or food products into containers. The slat segment is comprised of a straight elongated bar, whose first surface contains a plurality of substantially cylindrical cavities separated by adjacent walls. Discrete products ready for packaging are deposited into contoured intake flutes which guide the pharmaceuticals, vitamin, or food products into the cavities within the slat segment. The products are then dispensed from the slat segment via contoured disposal flutes connected to each cavity, to eventually be deposited into containers being conveyed proximate the packaging machine. Salient thermal radiation blocks are arranged along a second surface of the slat segment, along with thermal radiation webs, which facilitate conduction of thermal radiation away from the slat segment. The slat segment thereby maintains maximum strength and stability and minimizes necessary maintenance of the slat. | 02-02-2012 |
Shahar Soloman, Las Vegas, NV US
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20150271306 | INTEGRATED MOBILE PHONE CASE AND LIGHTER COMPARTMENT - An integrated cell phone case and lighter comprises a phone casing, a bottom backing and a removable lighter and is sized and shaped to be placed on over a conventional cell phone in a manner such that it substantially covers the cell phone on all sides except for the side with the touch screen. The phone casing is a viscoelastic body that includes a phone holding level for holding a cell phone and a lighter holding level adapted to enable a lighter to be stored in a the lighter holding compartment thereon. The bottom backing is a rigid shell which is sized to fit over the combined cell phone and phone casing assembly. The removable lighter is defined by a battery operated, butane refillable lighter in a modified rectangular exterior that includes side recesses and a finger gripping. | 09-24-2015 |