Ni, US
Ben Xuehai Ni, Canton, MI US
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20100170468 | BEARING SYSTEM FOR AUTOMOTIVE ENGINE - The bearing system for an automotive engine includes a first bearing support structure formed in a cylinder block bulkhead and having a first bearing insert. A second bearing support structure is removably mounted to the first bearing support structure and contains a second bearing insert. A lubrication channel formed in an inside diameter of the first bearing insert and an inside diameter of the second bearing insert extends along a portion of the first bearing insert from a smaller bearing clearance position offset from a first bearing parting line and into a smaller bearing clearance portion of the second bearing insert extending past a second bearing parting line. The lubrication channel provides an improved flow of oil to a drilled passage formed in a shaft, such as a crankshaft, to feed oil to various bearings, such as connecting rod bearings, while reducing oil leakage from such a bearing system. | 07-08-2010 |
20100192898 | OIL SUPPLY SYSTEM FOR INTERNAL COMBUSTION ENGINE WITH DUAL MODE PRESSURE LIMITING VALVE - A lubricating oil supply system for internal combustion engine includes an oil reservoir and oil pump connected with a lubrication distribution network including a piloted pressure relief valve which selectively controls the pressure within the distribution network to at least one pressure value that is less than the maximum pressure produced by a primary pressure relief valve associated with the oil pump, while also protecting the lubrication distribution network from an unwanted overpressure condition. | 08-05-2010 |
20100192899 | OIL SUPPLY SYSTEM FOR INTERNAL COMBUSTION ENGINE - A lubricating oil supply system for internal combustion engine includes an oil reservoir and oil pump connected with a lubrication distribution network including a pressure controller which selectively controls the pressure within the distribution network to at least one pressure value that is less than the maximum pressure produced by a pressure relief valve associated with the oil pump. | 08-05-2010 |
20130192557 | OIL PRESSURE SCHEDULING BASED ON ENGINE ACCELERATION - Systems and methods are disclosed for adjusting oil pressure supplied to engine components. In one example approach, a method for controlling oil flow in an engine comprises adjusting oil pressure supplied to the engine based on engine acceleration. For example, engine acceleration may be used to predict future engine lubrication requirements so that oil pressure adjustments may be scheduled accordingly. | 08-01-2013 |
Beta Yuhong Ni, West Linn, OR US
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20090099980 | SYSTEM AND METHOD OF BILLING FOR PRINTING SERVICE COSTS BY EXAMINING THE CONTENT OF A PAGE - A system and method of billing for printing service costs can examine content of a page and apply a cost function to approximate the cost of printing the page. Examining the content of the page may include detecting at least one object in the page and determining an approximate area of coverage of the detected object within the at least one object in the page. The cost function can approximate the cost of printing the page using the detected object and the determined approximate area of coverage of the detected object. | 04-16-2009 |
Bin Ni, Lafayette, IN US
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20100097317 | METHODS AND APPARATUS TO PROVIDE A HANDHELD POINTER-BASED USER INTERFACE - Methods and apparatus to provide a handheld pointer-based user interface are described herein. An example apparatus includes a wireless pointer component and one or more base components. The wireless pointer component is configured to transmit one or more human-computer interaction (HCI) signals associated with an HCI event via a first communication link. One or more base components are operatively coupled to a screen of a display to receive the one or more HCI signals from the wireless pointer component via the first communication link. Further, the one or more base components are configured to generate at least one of operating information and position information of the wireless pointer component based on the one or more HCI signals, and to transmit the at least one of operating information and position information to a processor configured to generate screen information on the screen of the display via a second communication link. | 04-22-2010 |
Chiyou Ni, Belle Mead, NJ US
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20110136833 | Tetrahydropyridinyl and Dihydropyrrolyl Compounds and the Use Thereof - The invention relates to tetrahydropyridinyl and dihydropyrrolyl compounds of Formula (I): and pharmaceutically acceptable salts, prodrugs, or solvates thereof, wherein X, Y, Z, R | 06-09-2011 |
20130150377 | Tetrahydropyridinyl and Dihydropyrrolyl Compounds and the Use Thereof - The invention relates to tetrahydropyridinyl and dihydropyrrolyl compounds of Formula (I): and pharmaceutically acceptable salts, prodrugs, or solvates thereof, wherein X, Y, Z, R | 06-13-2013 |
20130296281 | Aryl Substituted Indoles and Their Use as Blockers of Sodium Channels - The invention relates to aryl and heteroaryl substituted compounds of Formula (I), and pharmaceutically acceptable salts, prodrugs, or solvates thereof, wherein G, R | 11-07-2013 |
20130303526 | Pyridine Compounds and the Uses Thereof - The invention relates to substituted pyridine compounds of Formula (I) and the pharmaceutically acceptable salts, prodrugs, and solvates thereof, wherein R | 11-14-2013 |
20130345211 | Pyridine Compounds as Sodium Channel Blockers - The invention relates to substituted pyridine compounds of Formula I: (I) or a pharmaceutically acceptable salt, prodrug, or solvate thereof wherein A | 12-26-2013 |
20140005212 | Substituted Pyridines as Sodium Channel Blockers | 01-02-2014 |
20140303139 | PYRIMIDINES AS SODIUM CHANNEL BLOCKERS - The present disclosure provides substituted pyrimidine compounds of Formula (I), and the pharmaceutically acceptable salts, prodrugs, and solvates thereof, wherein A | 10-09-2014 |
20150259293 | PYRIDINE COMPOUNDS AND THE USES THEREOF - The invention relates to substituted pyridine compounds of Formula (I) and the pharmaceutically acceptable salts, prodrugs, and solvates thereof, wherein R | 09-17-2015 |
Chuan Ni, Allen, TX US
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20090309559 | AUTOMATICALLY CONFIGURABLE DUAL REGULATOR TYPE CIRCUITS AND METHODS - Automatically configurable dual regulator type circuits and methods are provided. On embodiment of the invention includes an automatically configurable dual regulator type circuit. The circuit comprises a high-side switching device (HS-SD) coupled to a low-side switching device (LS-SD) at an output node. The circuit further comprises a control logic device that turns on the HS-SD to provide an output current to a user selected circuit configuration through the output node, turns off the HS-SD after a voltage fed back from an output terminal of the user selected circuit configuration exceeds a first threshold and sets a regulator type configuration mode based on the presence or absence of a flyback period at the output node after the HS-SD has been turned off. | 12-17-2009 |
20120155144 | FAST RESPONSE CIRCUITS AND METHODS FOR FRAM POWER LOSS PROTECTION - A circuit to protect data on an FRAM during a read operation includes an FRAM voltage regulator having an output to supply an FRAM operating voltage to the FRAM. A voltage monitor monitors a supply voltage for the FRAM to generate a voltage fault signal if the supply voltage falls below a predetermined value. And a circuit responsive to the voltage fault signal maintains the FRAM operating voltage above a voltage required to assure data integrity of the FRAM for a sufficient time required to perform an FRAM read operation. | 06-21-2012 |
Chunjian Ni, Durham, NC US
Patent application number | Description | Published |
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20110292593 | INDEPENDENTLY OPERABLE IONIC AIR MOVING DEVICES FOR ZONAL CONTROL OF AIR FLOW THROUGH A CHASSIS - Airflow in a computer chassis may be enhanced or reduced to affect cooling of heat generating devices using an ionic air moving device. A plurality of ionic air moving devices enhance or reduce airflow through a plurality of fluidically parallel airflow zones of the computer chassis in an airflow direction established by a nonionic air moving device. Each ionic air moving device comprises an ion emitter electrode disposed a spaced distance from a collector electrode, wherein a controller independently controls an electrical potential between the emitter and collector electrodes of each ionic air moving device for affecting the rate of airflow through one or more of the plurality of airflow zones. | 12-01-2011 |
20120036998 | ELECTROSTATIC CONTROL OF AIR FLOW TO THE INLET OPENING OF AN AXIAL FAN - An air moving apparatus comprises an axial fan and an electrostatic device. The axial fan has a rotatable shaft defining a central axis of the axial fan, a plurality of blades secured to the shaft, and an air inlet opening. The electrostatic device is disposed immediately upstream of the air inlet opening of the axial fan, and includes a collector and an emitter. In one embodiment, the electrostatic device comprises a cylindrical collector coupled to ground and has a central axis aligned with the central axis of the axial fan, wherein the cylindrical collector has an inner diameter that is substantially the same as the diameter of an air inlet opening to the axial fan. The electrostatic device further comprises a plurality of emitter wires coupled to a terminal of a direct current source and extending lengthwise within the cylindrical collector. The axial fan moves air longitudinally through an air inlet opening of the axial fan, and, during operation of the axial fan, the application of an electrical potential between an emitter and a collector causes ionic air movement radially outwardly away from a central axis of the axial fan. | 02-16-2012 |
Chunjian Ni, Cary, NC US
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20130120926 | USER-SERVICEABLE LIQUID DIMM COOLING SYSTEM - A cooling system for a memory module comprises a heat conduction assembly for conducting heat from the memory module to liquid-cooled mounting blocks. In one embodiment, each heat conduction assembly includes a frame having opposing first and second supports, first and second heat spreader plates each extending from the first support to the second support, and a pair of flattened heat pipes each extending along a respective one of the heat spreader plates from the first support to the second support. The liquid-cooled mounting blocks releasably support the heat conduction assembly over a memory module socket with the memory module between the heat spreader plates. | 05-16-2013 |
20130126145 | HEAT SINK WITH ORIENTABLE FINS - A heat sink comprises a first thermally conductive base having a first face to thermally engage a heat-generating electronic component and a second thermally conductive base with a plurality of fins on a first face and a second face to engage the first base. The fins on the second base are positionable in either of two orientations relative to the heat-generating electronic component to which the heat sink is coupled. The fins are selectively placed in the orientation that best utilizes the direction of air flow available to the heat sink. The orientable fins of the heat sink afford flexibility in arranging the heat-generating electronic component on a circuit board or in arranging a circuit board within a computer chassis. | 05-23-2013 |
20130133859 | HEAT SINK WITH HEAT BUS AND FIN STRUCTURE - A heat sink to remove heat from a processor within a chassis to air moving through a fin structure on the heat sink. An embodiment of the heat sink comprises a heat bus engaging the processor to conduct heat from the processor to a fin structure having interconnected, repeating cellular air channels. A U-shaped heat bus comprises a base and first and second legs extending therefrom connected to opposite sides of the fin structure. An embodiment of the heat bus has a solid conductive core to conductively transfer heat from the processor through the base and the first and second legs to sides of the fin structure. Alternately, an embodiment of the heat bus has a hollow core containing a fluid to evaporatively transfer heat from the processor through the base and the first and second legs to sides of the fin structure. | 05-30-2013 |
20130135812 | LIQUID-COOLING MEMORY MODULES WITH LIQUID FLOW PIPES BETWEEN MEMORY MODULE SOCKETS - A liquid-cooled computer memory system includes first and second blocks in fluid communication with a chilled liquid source. A plurality of spaced-apart heat transfer pipes extend along a system board between memory module sockets from the first manifold block to the second manifold block. The heat transfer pipes may be liquid flow pipes circulating the chilled liquid between the memory module sockets. Alternatively, the heat transfer pipes may be closed heat pipes that conduct heat from the memory modules to the liquid-cooled blocks. A separate heat spreader is provided to thermally bridge each memory module to the adjacent heat transfer pipes. | 05-30-2013 |
20130138262 | HEAT SINK WITH ORIENTABLE FINS - A heat sink comprises a plurality of fins that may be positioned in a plurality of orientations relative to a heat-generating electronic component to which the heat sink is thermally coupled. A controller may be used to detect an elevated processor temperature and to activate a drive member to automatically adjust the orientation of fins on the heat sink. The fins may be moved and aligned with an air flow made over the heat sink. The adjustable-fin heat sink affords added flexibility in arranging a processor or other heat-generating electronic component on a circuit board. The orientation or position of the heat sink fins may also be automatically changed in response to a change in the air flow direction as manifested by a rise in the temperature of the heat sink or the heat-generating member. | 05-30-2013 |
20130168068 | THERMALLY ENHANCED COLD PLATE HAVING HIGH CONDUCTIVITY THERMAL TRANSFER PATHS - A cold plate comprises a cold plate body having a base for thermally engaging a heat-generating device, a plurality of internal channels extending through the cold plate body for the passage of a liquid coolant, a first region between the base and the plurality of internal channels, and a second region between the plurality of internal channels and a top that is generally opposite the base from the plurality of internal channels. The cold plate body is made from a first thermally conductive material. The cold plate also comprises at least one thermally conductive member extending around the plurality of channels from the first region below the plurality of channels to the second region above the plurality of channels. The at least one thermally conductive member has a greater thermal conductivity than the first thermally conductive material to move heat from the first region to the second region. | 07-04-2013 |
20130177391 | ELECTROSTATIC CONTROL OF AIR FLOW TO THE INLET OPENING OF AN AXIAL FAN - A method of modifying the airflow to the inlet of an axial fan comprises operating an axial fan to move air longitudinally through an air inlet opening of the axial fan, and, during operation of the axial fan, applying an electrical potential between an emitter and a collector to cause ionic air movement radially outwardly away from a central axis of the axial fan, wherein the radially outward air movement is caused upstream of the axial fan before the air reaches the air inlet opening. | 07-11-2013 |
20140230234 | ELECTROHYDRODYNAMIC AIRFLOW ACROSS A HEAT SINK USING A NON-PLANAR ION EMITTER ARRAY - A method of cooling a heat generating device includes positioning a base of an electronically conductive heat sink in thermal communication with a heat generating device, wherein the heat sink includes a plurality of fins extending in a longitudinal direction from a first end to a second end, and coupling the heat sink to ground. The method further includes emitting ions from a plurality of ion emitter elements disposed in a non-planar pattern along the first ends of the plurality of fins, wherein at least three ion emitter elements are equidistant from the first end of the nearest fin and are positioned in an arc having an axis that extends along the first end of the nearest fin. | 08-21-2014 |
Dianne Ni, Katy, TX US
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20140270393 | SYSTEMS AND METHODS FOR IMPROVING DIRECT NUMERICAL SIMULATION OF MATERIAL PROPERTIES FROM ROCK SAMPLES AND DETERMINING UNCERTAINTY IN THE MATERIAL PROPERTIES - A testing system can analyze a 3D digital volume of a material sample. The testing system can define several test volumes with each test volume including a different numbers of voxels. The test volumes can define the size of portions of the 3D digital volume to analyze. For each test volume, the testing system can acquire two adjacent portions of 3D digital volume that are the size of the test volume currently being analyzed. The testing system can calculate a petrophysical property value for the two adjacent portions of the 3D digital volume and can calculate the difference value between the two adjacent portions of the 3D digital volume. The testing system can repeat the process for the different test volumes. The testing system can plot the mean difference values for the different test volumes. The testing system can analyze the plot to determine a representative elementary volume that meets a predefined difference value. | 09-18-2014 |
20140270394 | Systems and Methods for Improving Direct Numerical Simulation of Material Properties from Rock Samples and Determining Uncertainty in the Material Properties - A testing system for analyzing a 3D digital volume of a material sample. The testing system defines several test volume sizes with each test volume size including a different numbers of voxels, defining the size of portions of the 3D digital volume to analyze. For each test volume size, the testing system acquires two adjacent portions of 3D digital volume at the test volume size currently being analyzed. The testing system calculates a material property value for the two adjacent portions of the 3D digital volume, and a difference value between the two adjacent portions of the 3D digital volume. The process is repeated over the different test volume sizes. The testing system calculates mean difference values for the different test volume sizes, from which it determines a representative elementary volume. | 09-18-2014 |
Feng Ni, Allston, MA US
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20130065875 | SMALL MOLECULE INHIBITORS OF HEPATITIS C VIRUS - The invention provides derivatives and analogues of triazatetracyclo[7.7.0.0 | 03-14-2013 |
Frank (zhi) Ni, Dexter, MI US
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20100175469 | Electrically heated fluid tube - An electrically heated, flexible fluid conduit or tube ( | 07-15-2010 |
Haihong Ni, Lexington, MA US
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20090048203 | SUBSTITUTED ADENINES AND THE USES THEREOF - This invention relates to compounds of Formula (I): and their use in the treatment of bacterial infections. | 02-19-2009 |
Haihong Ni, Waltham, MA US
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20080312211 | Antibacterial Pyrrolopyridines, Pyrrolopyrimidines and Pyrroloazepines-154 - Compounds of formula (I) and their pharmaceutically acceptable salts are described: formula (I). Processes for their preparation, pharmaceutical compositions containing them, their use as medicaments and their use in the treatment of bacterial infections are also described. | 12-18-2008 |
20090118220 | SUBSTITUTED ADENINES AND THE USES THEREOF - This invention relates to compounds of Formula I: | 05-07-2009 |
20100179150 | ANTIBACTERIAL PIPERDINE DERIVATIVES - Compounds of formula (I) and their pharmaceutically acceptable salts are described. Processes for their preparation, pharmaceutical compositions containing them, their use as medicaments and their use in the treatment of bacterial infections are also described. | 07-15-2010 |
20130150366 | CHEMICAL COMPOUNDS - Compounds of formula (I) and their pharmaceutically acceptable salts are described. Processes for their preparation, pharmaceutical compositions containing them, their use in the treatment of bacterial infections are also described. | 06-13-2013 |
Heyu Ni US
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20150290294 | METHODS FOR INHIBITING PLATELET AGGREGATION USING GLP-1 RECEPTOR AGONISTS - Methods for inhibiting platelet aggregation using glucagon-like peptide-1 receptor (GLP-1R) agonists are disclosed. GLP-1 receptors are demonstrated to be expressed in platelets and/or megakaryocytes. Activation of GLP-1 receptors by GLP-1 agonists, such as GLP-1 and exendin-4, inhibited thrombin-induced platelet aggregation. | 10-15-2015 |
Hong Ni, Austin, TX US
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20120301885 | CYTOGENIC ANALYSIS OF METAPHASE CHROMOSOMES - The present invention relates to methods and systems for analyzing chromosomes, and in particular to methods and systems for simultaneously performing banding and in situ hybridization on metaphase chromosomes. | 11-29-2012 |
20130196880 | PATTERNED DEVICES AND METHODS FOR DETECTING ANALYTES - Disclosed herein are devices for the detection of target molecules and methods for their use and production. The disclosed devices may include optically decipherable patterns that facilitate an understanding of binding events between a target molecule and a detection molecule. In one example, a device includes a macroscopic pattern constructed using microscopic elements that can be chromogenically developed to memorialize a binding event. In another example, a device includes characters that can be chromogenically developed using an automated slide staining instrument to memorialize a binding event. | 08-01-2013 |
Hua Ni, Chantilly, VA US
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20080243580 | METHOD AND SYSTEM FOR SERVICES PARTNER LABOR RATE OPTIMIZATION - Effective and efficient multi-vendor labor rate negotiations are supported by using a minimization algorithm to provide an optimized total cost of staffing allocation. Critical impact factors are also provided to identify specific labor categories or other vendor attributes that have the greatest impact on the total staffing allocation cost. By varying the elements identified by the critical impact factors and using the computer-implemented optimization algorithm, real-time changes are available to the vendors to assist in the negotiations of services contract agreements. | 10-02-2008 |
Jian Ni, Rockville, MD US
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20080317756 | Antibodies to Chemokine Alpha-5 - The present invention relates to a novel CKα-5 protein which is a member of the alpha chemokine family. In particular, isolated nucleic acid molecules are provided encoding the human CKα-5 protein. CKα-5 polypeptides are also provided, as are vectors, host cells and recombinant methods for producing the same. Antibodies and fragments thereof that specifically bind to CKα-5 polypeptides are also disclosed, as are compositions and methods for making such antibodies. The invention further relates to screening methods for identifying agonists and antagonists of CKα-5 activity. Also provided are diagnostic methods for detecting immune system-related disorders and therapeutic methods for treating immune system-related disorders. | 12-25-2008 |
Jian Ni, Gaithersburg, MD US
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20100130417 | TRANSFORMING GROWTH FACTOR ALPHA HII - The present invention discloses transforming growth factor alpha HII polypeptides and polynucleotides encoding such polypeptides. Also provided is a procedure for producing such polypeptides by recombinant techniques and therapeutic uses of the polypeptides which include stimulating wound healing, treating neurological disorders, treating ocular disorders, treating kidney and liver disorders, and stimulating embryogenesis and angiogenesis. Also disclosed are antagonists against such polypeptides and their use as a therapeutic to treat neoplasia. Also disclosed are diagnostic assays for detecting altered levels of the polypeptide of the present invention and mutations in the nucleic acid sequences which encode the polypeptides of the present invention. | 05-27-2010 |
Jianwen Ni, Franklin, TN US
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20100071829 | Accelerated Curing Adhesive For Wood Composites - An adhesive system for, inter alia, the manufacturing of wood composites, which includes a MDI adhesive and a formaldehyde-containing resin accelerator. | 03-25-2010 |
20100075153 | Catalyzed Isocyanate Adhesive System For Wood Composites - An adhesive system for, inter alia, the manufacturing of wood composites, which includes a two part adhesive system with an isocyanate polymer and an isocyanate catalyst in an thermosetting resin. | 03-25-2010 |
Jie Ni, Portland, OR US
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20140267322 | DISPLAY SIGNAL BUFFER - Briefly, embodiments of methods or systems for a display signal buffer are disclosed. | 09-18-2014 |
Jun Ni, Maumea, OH US
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20150122319 | APCVD OF DOPED TITANIUM OXIDE AND THE COATED ARTICLE MADE THEREBY - A method of making a doped titanium oxide coating in a float glass manufacturing process and the coated glass article made thereby wherein the dopant is a niobium or tantalum compound. The doped titanium oxide coating preferably exhibits an electrical conductivity > | 05-07-2015 |
Jun Ni, Liberty Lake, WA US
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20100091909 | SYSTEMS AND METHODS FOR UNEQUAL ERROR PROTECTION AND SOFT DECISION CALCULATIONS - A wireless communications device ( | 04-15-2010 |
20110182301 | TDMA VOICE COMMUNICATION METHOD AND APPARATUS - In accordance with a first aspect, a method, apparatus and system is disclosed for communicating within a TDMA communication system comprising receiving data from a plurality of transmitters in a stream of TDMA super-frames, wherein each transmitter transmits payload data in one particular frame within a defined super-frame, each super-frame comprising M frames, where M is a positive integer greater than one, determining, using a processor, a quality of received data from said transmitters, and if the quality of received data from one of said transmitters is below a quality threshold, granting said one of said transmitters the right to transmit data within a second frame in said super-frames, and collectively processing in a processor said data in both frames of said super-frame assigned to said one of said transmitters to reconstruct said data from said one of said transmitters Also, a method, apparatus and system for processing data received in a TDMA communication system utilizing a stream of TDMA super-frames, each super-frame having a structure comprising M frames, each frame designed to carry data of a duration of Y time units, from a different communication channel, where Y is a positive integer, said method comprising dividing said super-frame into N/M hyper-frames, where N is a factor of M, and partitioning said data from each of said transmitters into mini-frames of duration Y/N and interleaving said mini-frames of data from each of said transmitters into a TDMA transport stream comprising super-frames of M*N mini-frame | 07-28-2011 |
20110182332 | METHOD AND APPARATUS FOR HIGH SPEED DATA TRANSMISSION MODULATION AND DEMODULATION - A method and apparatus for communicating wirelessly comprising creating a plurality of sub-carrier signals by quadrature amplitude modulating data onto a plurality of sub-carrier frequencies spaced apart by a sub-carrier frequency spacing interval, frequency shifting the sub-carrier signals by one half of the sub-carrier frequency spacing interval, and modulating the sub-carrier signals onto a radio frequency carrier wave for wireless transmission. | 07-28-2011 |
20130021924 | SYSTEMS AND METHODS FOR TIME DIVISION MULTIPLE ACCESS COMMUNICATION WITH AUTOMATIC REPEAT REQUEST ERROR CONTROL | 01-24-2013 |
Jun Ni, Burlington, MA US
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20090033418 | Training sequence and digital linearization process for power amplifier - A training sequence and digital linearization process for a power amplifier are provided. In particular, a system for maintaining linear operation of an amplifier is includes an estimation component configured to determine compensation coefficients. The system further includes a digital pre-distorter configured to compensate for non-linear operation of the amplifier based on the compensation coefficients. The compensation coefficients are determined based on a training sequence signal having a time synchronization portion and a linearization sequence portion. | 02-05-2009 |
Jun Ni, Newark, DE US
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20110246385 | AUTOMATICALLY RECALIBRATING RISK MODELS - Methods, computer readable media, and apparatuses for automatically recalibrating risk models are presented. An identifier of a modeling function may be received. The modeling function may have at least one input variable and a first set of one or more coefficients. Updated performance data that includes at least one input value corresponding to the at least one input variable may be received from a data source. Then, a second set of one or more coefficients may be calculated for the modeling function based on the updated performance data. If it is subsequently determined that the modeling function more accurately models the updated performance data when the second set of one or more coefficients is used in computing a result of the modeling function, then the first set of one or more coefficients may be replaced with the second set of one or more coefficients to recalibrate the modeling function. | 10-06-2011 |
Kai Ni, Atlanta, GA US
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20110169923 | Flow Separation for Stereo Visual Odometry - In a method for determining a translation and a rotation of a platform, at least a first frame and a previous frame are generated. Points are matched between images generated by two stereoscopic sensors. Points are matched to corresponding stereo feature matches between two frames, thereby generating a set of putative matches. Putative matches that are nearer to the platform than a threshold are categorized as near features. Putative matches that are farther to the platform than the threshold are categorized as distance features. The rotation of the platform is determined by measuring a positional change in two of the distant features. The translation of the platform is determined by compensating one of the near features for the rotation and then measuring a change in one of the near features measured between the first frame and the second frame. | 07-14-2011 |
20130121558 | Point Selection in Bundle Adjustment - In an embodiment, a method comprises receiving a set of three dimensional ( | 05-16-2013 |
20130124147 | Random Sample Consensus for Groups of Data - In one embodiment, a computer accessible storage medium stores a plurality of instructions which, when executed: group a set of reconstructed three dimensional (3D) points derived from image data into a plurality of groups based on one or more attributes of the 3D points; select one or more groups from the plurality of groups; and sample data from the selected groups, wherein the sampled data is input to a consensus estimator to generate a model that describes a 3D model of a scene captured by the image data. Other embodiments may bias sampling into a consensus estimator for any data set, based on relative quality of the data set. | 05-16-2013 |
Liming Ni, Duluth, GA US
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20080280974 | Spiro compounds for treatment of inflammatory disorders - Provided are compounds, pharmaceutical compositions and methods of treatment or prophylaxis of an inflammatory condition, in particular asthma. The compounds are of the general Formula I, or a pharmaceutically acceptable salt, ester, prodrug or derivative thereof: | 11-13-2008 |
Ling Ni, Dallas, TX US
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20080233140 | Therapeutic Applications of Activation of Human Antigen-Presenting Cells Through Dectin-1 - The present invention includes compositions and methods for binding Dectin-1 on immune cells with anti-Dectin-1-specific antibodies or fragment thereof capable of activating the immune cells. | 09-25-2008 |
20120128710 | Enhancement of Pathogen-Specific Memory Th17 Cell Responses - Compositions and methods for enhancing Th1/Th17 cell responses and decreasing Th2 cell responses are disclosed herein. In various embodiments the present invention describes activation of human dendritic cells and enhancement of antigen-specific T cell responses in a Dectin-1-expressing human dendritic cells comprising an anti-Dectin-1-specific antibody or fragment thereof fused with one or more antigens. TLR2 ligands may also be included to enhance the activation and for enhancement of T-cell responses. Further, the invention also includes methods based on the compositions described herein for the treatment of pathogenic infections. | 05-24-2012 |
20140322214 | THERAPEUTIC APPLICATIONS OF ACTIVATION OF HUMAN ANTIGEN-PRESENTING CELLS THROUGH DECTIN-1 - The present invention includes compositions and methods for binding Dectin-1 on immune cells with anti-Dectin-1-specific antibodies or fragment thereof capable of activating the immune cells. | 10-30-2014 |
20150064205 | ENHANCEMENT OF PATHOGEN-SPECIFIC MEMORY TH17 CELL RESPONSES - Compositions and methods for enhancing Th1/Th17 cell responses and decreasing Th2 cell responses are disclosed herein. In various embodiments the present invention describes activation of human dendritic cells and enhancement of antigen-specific T cell responses in a Dectin-1-expressing human dendritic cells comprising an anti-Dectin-1-specific antibody or fragment thereof fused with one or more antigens. TLR2 ligands may also be included to enhance the activation and for enhancement of T-cell responses. Further, the invention also includes methods based on the compositions described herein for the treatment of pathogenic infections. | 03-05-2015 |
Liqin Ni, Morrisville, NC US
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20130162149 | Solid-State Lighting Apparatus Including an Energy Storage Module for Applying Power to a Light Source Element During Low Power Intervals and Methods of Operating the Same - A lighting apparatus includes a string of Light Emitting Diode (LED) sets coupled in series, each set including at least one LED, a light spreading circuit configured to incrementally turn on respective ones of the LED sets responsive to a power signal, and an energy storage module that is configured to store energy during a first interval of a period of the power signal and to apply the stored energy to the string during a second interval of the period of the power signal. | 06-27-2013 |
20130162153 | Solid-State Lighting Apparatus Including Current Diversion Controlled by Lighting Device Bias States and Current Limiting Using a Passive Electrical Component - A lighting apparatus includes a string of light emitting diode (LED) sets coupled in series where each set includes at least one LED. A current diversion circuit is coupled to the string and is configured to operate responsive to a bias state transition of one of the LED sets to direct current away from another one of the LED sets. A current limiting circuit is coupled in series with the string and is configured to conduct current responsive to a forward biasing of all of the LED sets. The current limiting circuit includes only passive electrical component(s). | 06-27-2013 |
20130307415 | SOLID-STATE LIGHTING APPARATUS AND METHODS USING SWITCHED ENERGY STORAGE - An apparatus includes at least one LED, at least one charge storage device and a switching circuit configured to route current through the least one LED to the at least one charge storage device for a first state of an applied voltage and to discharge the at least one charge storage device via the at least one LED for a second state of the applied voltage. The apparatus may further include a current control circuit coupled in series with the at least one LED. | 11-21-2013 |
Liqin Ni, Cary, NC US
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20140077709 | SOLID-STATE LIGHTING APPARATUS AND METHODS USING ENERGY STORAGE WITH SEGMENT CONTROL - A lighting apparatus includes a rectifier circuit configured to be coupled to an AC source and to produce a rectified voltage from an AC voltage and a string including at least two serially-connected LED segments and coupled to the rectifier circuit. A segment control circuit is configured to selectively bypass at least one segment of the string responsive to the rectified voltage. An energy storage circuit is coupled to the rectifier circuit and controls current flow between at least one energy storage device and the string. A control circuit controls the segment control circuit and the energy storage circuit. The segment control circuit may support a current from the rectifier circuit through all of the segments in the string circuit at a peak of the rectified voltage and the energy storage circuit may charge the at least one energy storage device to a voltage near the peak of the rectified voltage. | 03-20-2014 |
20140119077 | Power Converter with Bias Voltage Regulation Circuit - A power conversion circuit includes a voltage boost circuit configured to generate an output voltage in response to an input voltage, a boost controller configured to control operation of the voltage boost circuit, and a bias voltage generation circuit configured to generate a bias voltage. The bias generation circuit is configured to regulate a level of the bias voltage in response to a level of the input voltage. | 05-01-2014 |
20140125229 | MULTI-SEGMENT LED LIGHTING APPARATUS CONFIGURATIONS - A solid state lighting apparatus can include a Light Emitting Diode (LED) string that includes a plurality of light emitting diode (LED) segments that are coupled in series with one another wherein a ratio of respective numbers of LEDs in each of the segments is about equal to a ratio of respective average powers for each of the respective segments. Other configurations are also disclosed. | 05-08-2014 |
20150137689 | SYSTEMS AND METHODS FOR A CURRENT SHARING DRIVER FOR LIGHT EMITTING DIODES - Systems and methods for a current sharing driver for light emitting diodes are disclosed. One disclosed system includes: a first string of LEDs; a second string of LEDs connected in parallel with the first string; a first current control device connected in series with the first string of LEDs; a second current control device connected in series with the second string of LEDs; a first voltage measurement device coupled to the first string of LEDs and the second string of LEDs, the first voltage measurement circuit coupled to the first current control device and configured to control the first current control device; and a second voltage measurement device coupled to the first string of LEDs and the second string of LEDs, the second voltage measurement circuit coupled to the second current control device and configured to control the second current control device. | 05-21-2015 |
Liqin Ni, Raleigh, NC US
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20130026923 | SOLID STATE LIGHTING APPARATUS AND METHODS OF FORMING - A solid state lighting apparatus can include a substrate having first and second opposing surfaces, where at least one of the opposing surfaces is configured to mount devices thereon. A string of chip-on-board light emitting diode (LED) sets, can be on the first surface of the substrate and coupled in series with one another. An ac voltage source input, from outside the solid state lighting apparatus, can be coupled to the first or second surface of the substrate. | 01-31-2013 |
20130069536 | SOLID-STATE LIGHTING APPARATUS AND METHODS USING CURRENT DIVERSION CONTROLLED BY LIGHTING DEVICE BIAS STATES - A lighting apparatus includes a string of light emitting diode (LED) sets coupled in series, each set including at least one LED. The apparatus further includes a plurality of current diversion circuits, respective ones of which are coupled to respective nodes of the string and configured to operate responsive to bias state transitions of respective ones of the LED sets. In some embodiments, a first one of the current diversion circuits is configured to conduct current via a first one of the LED sets and is configured to be turned off responsive to current through a second one of the LED sets. The first one of the current diversion circuits may be configured to conduct current responsive to a forward biasing of the first one of the LED sets and the second one of the current diversion circuit may be configured to conduct current responsive to a forward biasing of a second one of the LED sets. | 03-21-2013 |
Nanting Ni, Atlanta, GA US
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20100137249 | COMPOSITIONS FOR REGULATING OR MODULATING QUORUM SENSING IN BACTERIA, METHODS OF USING THE COMPOUNDS, AND METHODS OF REGULATING OR MODULATING QUORUM SENSING IN BACTERIA - The present disclosure encompasses compounds and compositions that are useful as specific AI-2 antagonists for the control of bacterial quorum sensing. Although the AI-2 antagonists according to the present disclosure may not have bactericidal effect, their ability to attenuate virulence, drug resistance, and/or biofilm formation have therapeutic benefits. In addition, the AI-2 antagonists of the present disclosure can also be used as tools to probe bacterial AI-2 functions. The present disclosure also encompasses methods for inhibiting or attenuating microbial virulence, biofilm formation, and drug resistance. The methods are suitable for preventing bacteria from accruing and forming extensive biofilms that may be a health or hygiene hazard or a physical issue, such as in the blockage of water or fuel lines. | 06-03-2010 |
20110144187 | APTAMER INHIBITION OF THROMBUS FORMATION - Boronic acid-modified DNA-based aptamers can be selected to recognize fibrinogen through binding at a glycosylation site and thus are useful for probing the effect of glycosylation pattern changes on the ability for fibrinogen to mediate blood coagulation. In addition, the aptamers of the disclosure also have anticoagulation effects due to their binding to fibrinogen and its cleavage product fibrin. The present disclosure, therefore, encompasses methods for inhibiting fibrin coagulation with an aptamer capable of specifically binding to a glycosylation site of fibrinogen or fibrin. The disclosure further provides oligonucleotide aptamers comprising at least one nucleotide having a boronic acid thereon, where the aptamer is capable of selectively binding to a glycosylation site of fibrinogen, or the derivative thereof. | 06-16-2011 |
Ni Ni, Ames, IA US
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20110212841 | Low resistivity contact to iron-pnictide superconductors - Method of making a low resistivity electrical connection between an electrical conductor and an iron pnictide superconductor involves connecting the electrical conductor and superconductor using a tin or tin-based material therebetween, such as using a tin or tin-based solder. The superconductor can be based on doped AFe | 09-01-2011 |
Nina Ni, Kendall Park, NJ US
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20100022457 | Sustained release glp-1 receptor modulators - The present invention provides novel pharmaceutical compositions comprising a human glucagon-like peptide-1 (GLP-1)-receptor modulator as an active ingredient in a sustained release formulation. | 01-28-2010 |
Ping Ni, Arlington, TX US
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20120147128 | Unification of Rosters in a Communication System - In one embodiment, a method for unifying rosters is provided. A client receives an escalation request associated with a first roster and responds to the escalation request. The client subscribes to the first roster as a participant in response to accepting the escalation request or subscribes to the first roster as an observer in response to denying the escalation request. The client identifies a second roster within the first roster that the client is not subscribed to and subscribes to the first roster as an observer. The client updates an entry associated with the client in the second roster to indicate that the client is subscribed to the first roster as one of a participant or an observer. The client additionally updates an entry associated with the client in the first roster to indicate that the client is subscribed to the second roster as an observer. | 06-14-2012 |
Qiang Ni, Baltimore, MD US
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20090317333 | PROTEIN KINASE A REPORTERS USEFUL IN HIGH THROUGHPUT ASSAYS - Protein kinase A reporters useful for obtaining measurements of protein kinase A activity with high spatial and temporal resolution can be used in high throughput assays to identify potentially therapeutic compounds. | 12-24-2009 |
Qingwen Ni, San Antonio, TX US
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20120070503 | Nanoparticle-Based Targeted Drug Delivery For In Vivo Bone Loss Mitigation - The present invention is directed to nanoparticle-based targeted drug delivery system for treatment of bone-loss. An enantiomeric phenothiazine is formulated into an in-vivo nanoparticle delivery system which may contain bone-targeting functionality. The nanoparticle formulations and their associated influence on whole bone porosity may now also be evaluated utilizing nuclear magnetic resonance (NMR) and relaxation time profiles, and in particular, median T | 03-22-2012 |
20130164381 | Nanoparticle-Based Targeted Drug Delivery For In Vivo Bone Loss Mitigation - The present invention is directed to nanoparticle-based targeted drug delivery system for treatment of bone-loss. An enantiomeric phenothiazine is formulated into an in-vivo nanoparticle delivery system which may contain bone-targeting functionality. The nanoparticle formulations and their associated influence on whole bone porosity may now also be evaluated utilizing nuclear magnetic resonance (NMR) and relaxation time profiles, and in particular, median T | 06-27-2013 |
20140044643 | Magnetic Calcium Phosphate Nanoparticles, Applications And Methods Of Preparation Thereof - Magnetic calcium phosphate particles are provided including particles comprising iron oxide and calcium phosphate. A chitosan coating is present on the particles, wherein the particles are less than or equal to 1,000 nm, are magnetic and exhibit a positive charge in the range of 1 mVolts to 60 mVolts. The particles are provided by preparing a calcium hydroxide solution and filtering the calcium hydroxide solution in a membrane filter. An iron chloride solution is formed and combined with the filtered calcium hydroxide solution. In addition, the phosphoric acid solution is combined with the combined solutions of iron chloride and calcium hydroxide, forming a mixture including particles comprising iron oxide and calcium phosphate. | 02-13-2014 |
Tao Ni, Christiansburg, VA US
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20090243957 | SYSTEMS AND METHODS FOR INFORMATION VISUALIZATION IN MULTI-DISPLAY ENVIRONMENTS - A system for visualizing information in multi-display environments (“MDEs”) using spatial and perspective-aware visualization techniques. In one implementation, the position of each display in a three-dimensional MDE is determined relative to the other displays. Graphical decoration objects and link paths are then used to help visualize relatedness and continuity between graphical data objects and graphical node-link objects on different displays. Three-dimensional decoration objects and link paths are also constructed to visualize interrelationships between data objects on displays that are not on the same plane. The visualization techniques can also be integrated with mobile displays using location sensing technology to dynamically adjust the decoration objects. Additionally, user tracking systems will dynamically adjust the decoration objects based on user perspective. The visualization techniques are applicable to physical, virtual or mixed physical-virtual environments. | 10-01-2009 |
Wangyang Ni, Ridgewood, NJ US
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20120201615 | Cubic Aluminum Titanium Nitride Coating and Method of Making Same - Coated cutting tools are disclosed which have a hard coating that includes at least one aluminum titanium nitride layer having a single phase structure of B1 cubic phase and a composition of (Al | 08-09-2012 |
Wangyang Ni, Parsippany, NJ US
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20130011692 | COATED ARTICLE HAVING YTTRIUM-CONTAINING COATINGS APPLIED BY PHYSICAL VAPOR DEPOSITION AND METHOD FOR MAKING THE SAME - A coated article has a substrate and a coating scheme, which has a PVD coating region. The PVD coating region contains aluminum, yttrium, nitrogen and at least one element selected from the group of titanium, zirconium, hafnium, vanadium, niobium, tantalum, chromium, molybdenum, tungsten and silicon. The sum of the aluminum and yttrium contents is between about 3 atomic percent and about 55 atomic percent of the sum of aluminum, yttrium and the other elements. The yttrium content is between about 0.5 atomic percent and about 5 atomic percent of the sum of aluminum, yttrium and the other elements. There is also a method of making the coated article that includes steps of providing the substrate and depositing the above coating scheme with the PVD coating region. | 01-10-2013 |
20130065081 | MULTILAYER COATED WEAR-RESISTANT MEMBER AND METHOD FOR MAKING THE SAME - A coated wear-resistant member, as well as a method for making the same, includes a substrate and a coating scheme. The coating scheme has a region of alternating coating sublayers. One coating sublayer is Ti | 03-14-2013 |
Wangyang Ni, Latrobe, PA US
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20080253846 | END MILL FOR ORBITAL DRILLING OF FIBER REINFORCED PLASTIC MATERIALS - A center or non-center cutting end mill for orbital drilling of fiber reinforced plastic (FRP) materials includes a shank, a neck, a cutting head and two or more flutes. The end mill has a tool geometry with the following features: a dish angle between about 2 degrees to about 6 degrees; a helix angle between about 5 degrees to about 18 degrees; an end teeth radial rake angle between about 0 degrees and about 15 degrees; a peripheral teeth radial rake angle between about 8 degrees and about 16 degrees; a gashing axial rake angle between about 3 degrees to about 10 degrees; and a primary clearance angle between about 10 degrees to about 18 degrees. The end mill is made from a tungsten carbide substrate with cemented cobalt in a range between about 3 to 10 wt. % and a diamond coating having a thickness in a range between about 8 to 20 μm. | 10-16-2008 |
20090155559 | Coated article with nanolayered coating scheme - A coated article that includes a substrate and a wear-resistant coating scheme. The coated article may be a cutting insert shown to improve performance in chip-forming material removal operations or a wear-resistant component used in chipless forming operations. The wear-resistant coating scheme has an underlayer and top layer containing aluminum, chromium, and nitrogen. The coating scheme also includes a mediate multi-periodicity nanolayer coating scheme containing titanium, aluminum, chromium and nitrogen. The mediate multi-periodicity nanolayer coating scheme includes a plurality of sets of alternating layer arrangements. Each one of the alternating layer arrangements has a base layer comprising titanium, aluminum and nitrogen and a nanolayer region having a plurality of sets of alternating nanolayers. Each set of alternating nanolayers has one nanolayer having aluminum, chromium, titanium and nitrogen and another nanolayer having aluminum, chromium, titanium and nitrogen. The base layer has a base layer thickness and the nanolayer region has a nanolayer region thickness. The base layer thickness is smaller than the nanolayer region thickness. | 06-18-2009 |
20100183383 | END MILL FOR ORBITAL DRILLING - A center or non-center cutting end mill for orbital drilling includes a shank having a shank diameter; a neck having a neck diameter; a cutting head having a cutting diameter; a corner radius; a dish angle; and a longitudinal axis, the cutting head including a forward cutting end having a convexly curved section located between the longitudinal axis and the corner radius, wherein the convexly curved section causes material removed from a workpiece to flow radially outward from an initial contact area toward the corner radius, thereby minimizing the accumulation of material in a central portion of the forward cutting end. | 07-22-2010 |
20110081539 | Aluminum Titanium Nitride Coating and Method of Making Same - Hard coatings and methods of making the hard coatings comprising aluminum titanium nitride which are usable on cutting tools are disclosed. The coatings include at least one aluminum titanium nitride layer having between about 0 and about 15 weight percent hexagonal phase and a composition of (Al | 04-07-2011 |
20110293909 | Multilayer Nitride Hard Coatings - A wear resistant multilayer nitride hard coating for substrates. The hard coating includes a first layer of titanium aluminum nitride and a second layer comprising a plurality of sublayer groups. Each sublayer group includes a first sublayer of titanium silicon nitride and a second sublayer of titanium aluminum nitride. The composition of the titanium aluminum nitride, both in the first layer and in the sublayer groups, is (Ti | 12-01-2011 |
20130157023 | MULTILAYER NITRIDE HARD COATINGS - A wear resistant multilayer nitride hard coating for substrates. The hard coating includes a first layer of titanium aluminum nitride and a second layer comprising a plurality of sublayer groups. Each sublayer group includes a first sublayer of titanium silicon nitride and a second sublayer of titanium aluminum nitride. The composition of the titanium aluminum nitride, both in the first layer and in the sublayer groups, is (Ti | 06-20-2013 |
Weiting Ni, Carmel, IN US
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20090221501 | MIXING AND MATCHING TC PROTEINS FOR PEST CONTROL - The subject invention relates to the surprising discovery that toxin complex (TC) proteins, obtainable from | 09-03-2009 |
Weiting W. Ni, Carmel, IN US
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20110008833 | PROTEIN PRODUCTION IN PLANT CELLS AND ASSOCIATED METHODS AND COMPOSITIONS - The present invention relates to methods and compositions for the expression of protein. Embodiments of methods may comprise the cleavage and repair of a nucleotide sequence encoding a highly expressed protein leading to a reduction in the expression of the highly expressed protein. | 01-13-2011 |
20130067617 | PLANTS HAVING STRESS RELATED TRAITS AND METHODS FOR MAKING THE SAME - This invention relates generally to a plant cell with increased yield, preferably under condition of transient and repetitive abiotic stress as compared to a corresponding non-transformed wild type plant cell by increasing or generating one or more activities of RING proteins in plants. | 03-14-2013 |
Xianfeng Ni, Sussex, WI US
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20090003679 | SYSTEM AND METHOD FOR A DIGITAL X-RAY RADIOGRAPHIC TOMOSYNTHESIS USER INTERFACE - A system and method for an improved digital X-ray radiographic tomosynthesis user interface and workflow. | 01-01-2009 |
20100290707 | IMAGE ACQUISITION METHOD, DEVICE AND RADIOGRAPHY SYSTEM - An image acquisition method includes determining the starting position, the ending position of a region of interest, and the value of overlap of the region of interest in the two adjacent sub-images, calculating the number of the sub-images required to be captured, the component of field of view at the direction of tube movement and the positions of the tube and the detector corresponding to each sub-image based on the starting position and the ending position of a region of interest and the value of the overlap. The method also includes moving the tube and the detector to each position and capturing the region of interest to obtain sub-images at the positions, and pasting the several sub-images together to form an image of the said region of interest. | 11-18-2010 |
20130136235 | PORTABLE RADIATION DETECTOR AND SYSTEM - A portable detector for use with an imaging system is disclosed. The portable detector automatically sets one or more operational states based on at least a determination as to whether the portable detector is connected to external power. An imaging system is also disclosed that ascertains whether the portable detector is connected via a tether. The imaging system may perform a compatibility check when connected to the portable detector to assess compatibility between the imaging system and the portable detector. | 05-30-2013 |
Xiaohua Ni, Baltimore, MD US
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20130123566 | RADIATION SENSITIZATION AGENTS FOR PROSTATE CANCER - Compositions and methods are provided for sensitizing neoplastic cells to radiotherapy. The invention provides aptamer-inhibitory nucleic acid chimeras that selectively inliibit the expression of radiosensitizing genes in neoplastic cells expressing a cell surface molecule that binds the aptamer. | 05-16-2013 |
Xingjie Ni, West Lafayette, IN US
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20150309218 | ULTRA-THIN, PLANAR, PLASMONIC METADEVICES - An ultra-thin planar device is used for arbitrary waveform formation on a micrometer scale, regardless of the incident light's polarization. Patterned perforations are made in a 30 nm-thick metal film, creating discrete phase shifts and forming a desired wavefront of cross-polarized, scattered light. The signal-to-noise ratio of these devices is at least one order of magnitude higher than current metallic nano-antenna designs. The focal length of a lens built on such principle can also be adjusted by changing the wavelength of the incident light. All proposed embodiments can be embedded, for example, on a chip or at the end of an optical fiber. | 10-29-2015 |
Xudong Ni, Woodinville, WA US
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20110178798 | ADAPTIVE AMBIENT SOUND SUPPRESSION AND SPEECH TRACKING - A device for suppressing ambient sounds from speech received by a microphone array is provided. One embodiment of the device comprises a microphone array, a processor, an analog-to-digital converter, and memory comprising instructions stored therein that are executable by the processor. The instructions stored in the memory are configured to receive a plurality of digital sound signals, each digital sound signal based on an analog sound signal originating at the microphone array, receive a multi-channel speaker signal, generate a monophonic approximation signal of the multi-channel speaker signal, apply a linear acoustic echo canceller to suppress a first ambient sound portion of each digital sound signal, generate a combined directionally-adaptive sound signal from a combination of each digital sound signal by a combination of time-invariant and adaptive beamforming techniques, and apply one or more nonlinear noise suppression techniques to suppress a second ambient sound portion of the combined directionally-adaptive sound signal. | 07-21-2011 |
20120245933 | ADAPTIVE AMBIENT SOUND SUPPRESSION AND SPEECH TRACKING - A device for suppressing ambient sounds from speech received by a microphone array is provided. One embodiment of the device comprises a microphone array, a processor, an analog-to-digital converter, and memory comprising instructions stored therein that are executable by the processor. The instructions stored in the memory are configured to receive a plurality of digital sound signals, each digital sound signal based on an analog sound signal originating at the microphone array, receive a multi-channel speaker signal, generate a monophonic approximation signal of the multi-channel speaker signal, apply a linear acoustic echo canceller to suppress a first ambient sound portion of each digital sound signal, generate a combined directionally-adaptive sound signal from a combination of each digital sound signal by a combination of time-invariant and adaptive beamforming techniques, and apply one or more nonlinear noise suppression techniques to suppress a second ambient sound portion of the combined directionally-adaptive sound signal. | 09-27-2012 |
Yajin Ni, Gaithersburg, MD US
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20130203152 | Method for Reducing DNA Impurities in Viral Compositions - A method for purification of viral compositions is provided. In particular, a method for reduction of unwanted residual DNA in a viral composition while retaining the immunogenicity of the virus itself is provided. The resulting immunogenic viral composition is substantially free of residual DNA, and is useful for the manufacture of medical products, such as vaccines designed for human or animal. | 08-08-2013 |
Yajin Ni, Germantown, MD US
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20110207226 | NON-INTEGRATING LENTI/ADENO-ASSOCIATED VIRUS HYBRID VECTOR SYSTEM - The present invention provides for a hybrid vector system for the purpose of therapeutic gene delivery where the system is used for a targeted integration of a therapeutic gene into a genome. The hybrid vector system comprises a hybrid vector made up of a non-integrating lentiviral vector and an adeno-associated vector, and a therapeutic gene. | 08-25-2011 |
Yan Ni, Westfield, NJ US
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20110306060 | PCSK9 IMMUNOASSAY - Methods of using PCSK | 12-15-2011 |
20120213794 | AX213 AND AX132 PSCK9 ANTAGONISTS AND VARIANTS - Antagonists of human proprotein convertase subtilisin-kexin type 9 (“PCSK9”) are disclosed. The disclosed antagonists are effective in the inhibition of PCSK9 function and, accordingly, present desirable antagonists for use in the treatment of conditions associated with PCSK9 activity. The present invention also discloses nucleic acid encoding said antagonists, vectors, host cells, and compositions comprising the antagonists. Methods of making PCSK9-specific antagonists as well as methods of using the antagonists for inhibiting or antagonizing PCSK9 function are also disclosed and form important additional aspects of the present disclosure. | 08-23-2012 |
20120219558 | ANTAGONISTS OF PCSK9 - Antagonists of human proprotein convertase subtilisin-kexin type 9 (PCSK9) are disclosed. Said antagonists are effective in the inhibition of PCSK9 function and thereby provide compositions of matter useful for the treatment of conditions associated with PCSK9 activity. The present invention further discloses nucleic acids encoding PCSK9 antagonists as well as methods of making and using PCSK9 antagonists. | 08-30-2012 |
20120231005 | AX1 AND AX189 PSCK9 ANTAGONISTS AND VARIANTS - Antagonists of human proprotein convertase subtilisin-kexin type 9 (“PCSK9”) are disclosed. The disclosed antagonists are effective in the inhibition of PCSK9 function and, accordingly, present desirable antagonists for use in the treatment of conditions associated with PCSK9 activity. The present invention also discloses nucleic acid encoding said antagonists, vectors, host cells, and compositions comprising the antagonists. Methods of making PCSK9-specific antagonists as well as methods of using the antagonists for inhibiting or antagonizing PCSK9 function are also disclosed and form important additional aspects of the present disclosure. | 09-13-2012 |
Yan G. Ni, Westfield, NJ US
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20120208208 | PCSK9 IMMUNOASSAY - Methods of using PCSK9 antagonists. More specifically, methods for measuring circulating PCSK9 levels in a biological sample by means of an immunoassay. | 08-16-2012 |
Yanyan Ni, Blacksburg, VA US
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20130142824 | NOVEL MODIFIED LIVE-ATTENUATED VACCINES (MLV) CREATED BY DNA SHUFFLING AGAINST PORCINE REPRODUCTIVE AND RESPIRATORY SYNDROME VIRUS (PRRSV) - The present invention provides a novel infectious cDNA clone of porcine reproductive and respiratory syndrome virus (PRRSV), particularly for PRRSV strain VR2385; an improved DNA-launched reverse genetics system for PRRSV; infectious chimeric PRRSV viruses generated through DNA shuffling; modified live- attenuated virus vaccines (MLV) using DNA shuffled chimeric viruses; chimeric viral proteins produced through shuffled chimeric viruses; PRRSV antigens and subunit vaccines based on shuffled chimeric viral proteins; and method of producing broadly protective PRRSV vaccines using DNA shuffling techniques. Particularly, the present invention provides infectious chimeric viruses generated by DNA shuffling of the GP5 genes of genetically distinct strains of PRRSV; modified live-attenuated vaccines comprise infectious chimeric viruses containing the shuffled GP5 genes and/or other shuffled PRRSV proteins (such as GP2, GP3, GP4, M, and non-structural proteins); broadly -protective subunit vaccines comprising PRRSV chimeric shuffled GP5 protein and/or other shuffled PRRSV proteins (such as GP2, GP3, GP4, M, and non-structural proteins). | 06-06-2013 |
Yawei Ni, College Station, TX US
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20130171181 | DPS FUSION PROTEINS FOR USE IN VACCINES AND DIAGNOSTICS - Novel nanoparticle fusion proteins comprising proteins or peptides fused to Dps (DNA-binding protein from starved cells) proteins are provided which bring forth distinct advantages for development of new and improved vaccines, diagnostic tests, and other biomedical products. | 07-04-2013 |
20150098966 | Influenza vaccines - An influenza vaccine comprising an influenza hemagglutinin-containing antigen which is subjected to a treatment at a suitable low pH or other suitable conditions to obtain a suitable degree of loss of potency, and the method of making it are provided. The vaccine not only induces an increased cross-reactive immune response and cross protection, but can also induce a strain-specific immune response and protection like current inactivated vaccines. A method of administering influenza vaccines is also provided to induce an increased cross-reactive immune response and cross protection, which is especially suitable for use in emergency situations such as a pandemic. | 04-09-2015 |
Yike Ni, Hillsborough, NJ US
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20100120762 | Triazine derivatives as inhibitors of phosphodiesterases - The invention relates to triazine derivatives of formula (I): | 05-13-2010 |
20100120763 | IMIDAZO[5,1-C][1,2,4]BENZOTRIAZINE DERIVATIVES AS INHIBITORS OF PHOSPHODIESTERASES - The invention relates to imidazo[5,1-c][1,2,4]benzotriazine derivatives of formula I: | 05-13-2010 |
Yike Ni, Monmouth Jct, NJ US
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20090143361 | Pyrido[3,2-E]Pyrazines, Process For Preparing The Same, And Their Use As Inhibitors Of Phosphodiesterase 10 - The invention relates to pyrido[3,2-e]pyrazines, to processes for preparing them, to pharmaceutical compositions which comprise these compounds and to the pharmaceutical use of these compounds, which are inhibitors of phosphodiesterase 10, as active compounds for treating central nervous system disorders, obesity, and metabolic disorders. | 06-04-2009 |
20090143367 | ARYL AND HETEROARYL FUSED IMIDAZO[1,5-a]PYRAZINES AS INHIBITORS OF PHOSPHODIESTERASE 10 - The invention relates to imidazo[1,5-a]pyrazine derivatives, to processes for preparing them, to pharmaceutical preparations which comprise these compounds and to the pharmaceutical use of these compounds, which are inhibitors of phosphodiesterase 10 (PDE10), as active compounds for treating central nervous system diseases of mammals, including humans. | 06-04-2009 |
Yonghao Ni US
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20150284141 | Anti-Static Articles and Materials - The present disclosure relates to anti-static articles and multi-layered materials comprising an electrically conductive layer and a support layer. | 10-08-2015 |
Zhi Ni, Dexter, MI US
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20130343959 | COMMON RAIL REDUCTANT INJECTION SYSTEM - An exhaust system including a selective catalytic reduction (SCR) component and an oxidation catalyst component. The exhaust system also includes an exhaust treatment fluid injection system for dispersing an exhaust treatment fluid into an exhaust stream at a location adjacent either the SCR component or the oxidation catalyst component, wherein the exhaust treatment fluid injection device includes a common rail that provides the exhaust treatment fluid under pressure to a plurality of injectors that dose the exhaust treatment fluid into the exhaust stream. The exhaust treatment fluid injection device also includes a return rail for returning unused exhaust treatment fluid to the fluid source. | 12-26-2013 |
Zhicheng Ni, Allentown, PA US
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20120121018 | Generating Single-Slice Pictures Using Paralellel Processors - A video encoding system generates (e.g., H.264) single-slice pictures using parallel processors. Each picture is divided horizontally into multiple segments, where each different parallel processor processes a different segment. Each parallel processor (other than the first parallel processor of the uppermost segment) only partially processes the macroblocks in the first row of its segment. Subsequently, a final processor completes the processing of the partially encoded, first-row macroblocks based on the encoding results for the macroblocks in the last row of the segment above and across the segment boundary. The encoding of the first-row macroblocks is constrained to enable the encoding of all other rows of macroblocks to be completed by the parallel processors, without relying on the final processor. | 05-17-2012 |