Toshiyoshi
Toshiyoshi Fujiwara, Okayama JP
Patent application number | Description | Published |
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20110044949 | ONCOLYTIC VIRUS REPLICATING SELECTIVELY IN TUMOR CELLS - By using a virus having a gene sequence comprising a telomerase promoter and an E1 gene (preferably a sequence comprising E1A gene, IRES sequence and E1B gene) or by using an anticancer agent comprising the virus, the virus replicates in cancer cells to thereby produce an efficient anticancer effect. | 02-24-2011 |
20110111480 | Telomelysin/GFP-expressing recombinant virus - The present invention provides a reagent for cancer cell detection or cancer diagnosis. The present invention relates to a reagent for cancer cell detection, comprising a recombinant virus where a replication cassette comprising a promoter from human telomerase, an E1A gene, an IRES sequence and an E1B gene in this order is integrated in E1 region of the viral genome and a labeling cassette comprising a gene encoding a labeling protein and a promoter capable of regulating the expression of the gene encoding the labeling protein is integrated in E3 region of the viral genome. | 05-12-2011 |
Toshiyoshi Fujiwara, Okayama-Shi JP
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20080233642 | MAMMALIAN IMMORTALIZED LIVER CELL - The present invention provides a mammalian immortalized liver cell obtained by transferring a cell proliferation factor gene located between a pair of site-specific recombination sequences into a mammalian liver cell. | 09-25-2008 |
20100150884 | Anticancer Agent to Be Combined with Telomelysin - The present invention relates to providing a pharmaceutical composition with a still more enhanced anticancer activity. Specifically, the present invention relates to a pharmaceutical composition for combination therapy for tumors, comprising a recombinant virus comprising a polynucleotide containing a promoter for human telomerase, an E1A gene, an IRES sequence and an E1B gene in this order, and a substance having an antitumor effect. | 06-17-2010 |
Toshiyoshi Ichikawa, Anjo-Shi JP
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20130248640 | WEB WINDING APPARATUS - A web winding apparatus comprises a cutter, a web pressing member and a roller which are movable together between two bobbins supported respectively by two rotational center members. The cutter cuts a web being transferred, the web pressing member presses an end portion of the web cut with the cutter on the bobbin being empty, and the roller transfers the web being transferred to come, toward the bobbins. The apparatus further comprises two peripheral covers independently turnable around the rotational center members and respectively covering parts of outer peripheral surfaces of the webs wound on the two bobbins. Each of the peripheral covers respectively having circumferential openings is turnable selectively to a first position to direct the circumferential opening toward the roller and a second position to partition the bobbin side covered thereby and the roller side. | 09-26-2013 |
20130248642 | WEB WINDING APPARATUS - A web winding apparatus comprises two bobbins each being able to wind a web thereon; a cutter provided movably between the bobbin on one side and the bobbin on the other side for cutting the web being transferred; and a web pressing member provided at a position to face the cutter so that the web being transferred is put between the web pressing member and the cutter. The web pressing member is provided movably together with the cutter between the two bobbins, is configured to operate as cutter receiving member which presses and cuts the web in cooperation with the cutter, and is further configured to press a cut end of the web so cut on the bobbin being empty while holding the cut end of the web, to wind the cut end on the bobbin being empty. | 09-26-2013 |
Toshiyoshi Watanabe, Tokyo JP
Patent application number | Description | Published |
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20100163742 | Silicon Drift X-Ray Detector - A silicon drift detector has an X-ray detection device, an electrode terminal subassembly for electrical connection, a Peltier device, and first and second shields formed between the electrode terminal subassembly and the Peltier device. The first shield is made of a material consisting chiefly of an element having an atomic number smaller than the average atomic numbers of the elements included in the material of the Peltier device. The second shield is made of a material consisting chiefly of an element having an atomic number greater than the atomic numbers of the elements included in the material of the Peltier device | 07-01-2010 |
Toshiyoshi Watanabe, Anpachi-Gun JP
Patent application number | Description | Published |
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20110129308 | PIN MIRROR CUTTER - A throw-away tip is mounted on a first tip mounting seat of a pin mirror cutter. In the throw-away tip, cutting edges are formed at intersecting ridgeline parts between a pair of oppositely disposed long side faces of a substantially trapezoidal flat-plate-shaped tip body, and upper and lower faces of the tip body. A thickness direction of the tip body is approximately aligned with a radial direction of the cutter body to provide curved edges formed in acute corner parts of the tip body for cutting. The tip is mounted on a second tip mounting seat of the pin mirror cutter such that the thickness direction of the tip body is approximately aligned with an axial direction of the cutter body to provide curved edges formed in obtuse corner parts of the tip body for cutting. | 06-02-2011 |