Brodkorb
Andre Brodkorb, Middleton IE
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20120156252 | METHOD OF PRODUCING MICROBEADS - A method for producing microbeads comprising an active component encapsulated within a gelled polymer matrix comprises the steps of providing a suspension of denatured whey protein and an active component, treating the suspension to generate microbeads, and immediately curing the microbeads by acidification. The microbeads are discrete droplets of gelled whey protein having an average diameter in the micron range (for example, from 80 to 500 microns) and which, suitably have a generally spherical shape. The microbeads are capable of surviving passage through the stomach, and delivering the encapsulated active agent in the instestine. Ex-vivo and in-vivo data shows that active agent encapsulated within microbeads retains its functionality upon delivery to the intestine, and that coating of the microcapsules allows targeted delivery of the active agent to the distal part of the intestine. | 06-21-2012 |
Andre Brodkorb, Midleton IE
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20150320097 | Compositions and Methods of Producing Microbeads - A method for producing microbeads comprising an active component encapsulated within a gelled polymer matrix comprises the steps of providing a suspension of denatured whey protein and an active component, treating the suspension to generate microbeads, and immediately curing the microbeads by acidification. The microbeads are discrete droplets of gelled whey protein having an average diameter in the micron range (for example, from 80 to 500 microns) and which suitably have a generally spherical shape. The microbeads are capable of surviving passage through the stomach, and delivering the encapsulated active agent in the intestine. Ex-vivo and in-vivo data shows that active agent encapsulated within microbeads retains its functionality upon delivery to the intestine, and that coating of the microcapsules allows targeted delivery of the active agent to the distal part of the intestine. | 11-12-2015 |
Florian Brodkorb, Steinfurt DE
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20150368380 | ANTIMICROBIAL POLYMER - The invention is directed to an antimicrobial polymer that can preferably be processed thermoplastically, a method for the preparation of said antimicrobial polymer and its use in antimicrobial treatment. The invention is further directed to polymer blends containing antimicrobial polymers and the use of special monomers in the preparation of antimicrobial polymers that can be processed thermoplastically. | 12-24-2015 |
Thomas Brodkorb, Wiesloch DE
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20100162226 | ZERO DOWNTIME MECHANISM FOR SOFTWARE UPGRADE OF A DISTRIBUTED COMPUTER SYSTEM - A system and a method for installing software upgrades in a distributed computer system with no downtime. In a distributed computer system with cluster architecture, a number of service requests are redirected from a first instance of the cluster to a second instance of the cluster for execution. An execution in progress of a service request is also redirected from the first instance of the cluster to the second instance of the cluster. The execution in progress proceeds from a state that is saved on a public store by the first instance of the cluster. A software patch is applied to one or more software components running on an application server node of the first instance of the cluster. A number of service requests are redirected from the second instance of the cluster to the first instance of the cluster for execution. An execution in progress of a service request is also redirected from the second instance of the cluster to the upgraded first instance of the cluster. The execution in progress proceeds from a state that is saved on the public store by the second instance of the cluster. The software patch is applies on the one or more software components running on an application server node of the second instance of the cluster. A number of new service requests are directed to the upgraded second instance of the cluster for processing. | 06-24-2010 |
20120131154 | Synchronous Transport of Business Configuration Data in a Distributed Computing System Environment - Methods, systems, and articles are provided for synchronously exchanging configuration settings in a distributed software system in which interrelated software-implemented business processes execute on both a service provider and a customer landscape. The service provider and the customer landscape each comprise at least one server that in turn include at least one data processor and memory. The service provider includes a test environment and a service provider production environment. The customer landscape includes a quality assurance (QA) environment and a customer landscape production environment. Such an arrangement allows for synchronous transfer of business configuration data in a distributed computing environment. | 05-24-2012 |
20120150940 | ENHANCED CONNECTIVITY IN DISTRIBUTED COMPUTING SYSTEMS - Techniques are provided for exchanging configuration settings in a distributed software system in which interrelated software processes execute on both a client system and a service provider. Automation scripts are generated and used by the client system and the service provider to establish and initiate respective test environments. Related apparatus, systems, techniques and articles are also described. | 06-14-2012 |
20150149259 | ENTERPRISE PERFORMANCE MANAGEMENT PLANNING MODEL FOR AN ENTERPRISE DATABASE - According to some embodiments, actual business data in an enterprise database may be used in accordance with an enterprise performance management planning model, stored and executed by a processor at the enterprise database, to automatically generate predicted business data. The predicted business data may then be stored in an instantiation of a plan data container at the enterprise database. | 05-28-2015 |
Thomas Brodkorb, Paradeisstr. DE
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20100088281 | Zero Downtime Maintenance Using A Mirror Approach - The subject matter disclosed herein provides methods and apparatus, including computer program products, for providing software updates. In one aspect there is provided a method. The method may include copying an application to a shadow system, the application used to upgrade the shadow system rather than a production system; copying data from the production system to the shadow system; selecting whether to lock changes to data in the production system or record changes to the data in the production system; recording one or more changes to data in the production system, the changes recorded in a container, when record changes has been selected; migrating recorded data in the container to the shadow system, so that the shadow system and production system are in a similar data state; and using the shadow system, upgraded with the application and at least one of data copied from the production system and recorded data from the container, for production rather than the production system. Related systems, apparatus, methods, and/or articles are also described. | 04-08-2010 |