Nguyen, MA
Andrew Anh Nguyen, Cambridge, MA US
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20140186350 | COMPOSITIONS AND METHODS FOR LONG ACTING MOLECULES - The invention relates, in part, to compositions and methods that utilize a peptide tag that binds to hemagglutanin (HA). The HA tag can be linked to a molecule such as a protein or nucleic acid which, when administered to the eye, results in an increase in ocular half-life and/or mean residence time, and or a decrease in ocular clearance of the protein or nucleic acid. The invention also encompasses methods for treating ocular disease, including retinal vascular disease, by administering a protein or nucleic acid linked to an HA peptide tag. | 07-03-2014 |
Anh Nguyen, Woburn, MA US
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20090306476 | AUTOMATED CONTROL OF IRRIGATION AND ASPIRATION IN A SINGLE-USE ENDOSCOPE - The present invention is an integrated and automated irrigation and aspiration system for use in an endoscopic imaging system. The system provides for the automated cleaning of poorly prepared patients during a colonoscopy procedure as well as automated cleaning of an imaging system of an endoscope. The invention analyzes images obtained from an image sensor to detect the presence of an obstructed field of view, whereupon a wash routine is initiated to remove the obstruction. The wash routine may be adjusted in accordance with environmental conditions within the patient that are sensed by one or more sensors within the endoscope. In another embodiment, insufflation is automatically controlled to inflate a patient's colon as a function of one or more sensor readings obtained from one or more environmental sensor(s) on the endoscope. | 12-10-2009 |
20120101334 | ENDOSCOPE HAVING AUTO-INSUFFLATION AND EXSUFFLATION - An endoscopic imaging system for examining a patient's body cavity includes an endoscope having a distal end, a proximal end and a number of lumens therein. One or more distal gas ports are disposed at or adjacent the distal end of the endoscope and one or more proximal gas ports are disposed proximal to the distal gas ports. Insufflation gas is delivered to the distal gas ports and withdrawn from the proximal gas ports or vice versa such that a gas bubble is formed in the body cavity and travels with the distal tip of the endoscope. | 04-26-2012 |
Daniel Nguyen, Boston, MA US
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20150100561 | TRANSITION FROM FIRST SEARCH RESULTS ENVIRONMENT TO SECOND SEARCH RESULTS ENVIRONMENT - Methods, systems, and apparatus, including computer programs encoded on a computer storage medium, for processing search results. In one aspect, a transition from a first search result environment to a second, different search result environment is done in a manner that preserves the user experience of focusing on a selected search result. The transition can be facilitated by an intermediate search result environment that appears during the transition from the first search result environment to the second search result environment. The intermediate search result environment displays search result data of a search result that was selected in the first search result environment. The search result data that is displayed is, for example, data that was provided for display in the first search result environment. For example, in the case of image search results, the search result data that is displayed is a thumbnail image of the image search result. | 04-09-2015 |
20160063074 | TRANSITION FROM FIRST SEARCH RESULTS ENVIRONMENT TO SECOND SEARCH RESULTS ENVIRONMENT - Methods, systems, and apparatus, including computer programs encoded on a computer storage medium, for processing search results. In one aspect, a transition from a first search result environment to a second, different search result environment is done in a manner that preserves the user experience of focusing on a selected search result. The transition can be facilitated by an intermediate search result environment that appears during the transition from the first search result environment to the second search result environment. The intermediate search result environment displays search result data of a search result that was selected in the first search result environment. The search result data that is displayed is, for example, data that was provided for display in the first search result environment. For example, in the case of image search results, the search result data that is displayed is a thumbnail image of the image search result. | 03-03-2016 |
Dat Nguyen, Wilmington, MA US
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20150378184 | SYSTEMS AND METHODS FOR LASER SYSTEMS WITH VARIABLE BEAM PARAMETER PRODUCT UTILIZING THERMO-OPTIC EFFECTS - In various embodiments, a beam-parameter adjustment system and focusing system alters a spatial power distribution of a radiation beam, via thermo-optic effects, before the beam is coupled into an optical fiber or delivered to a workpiece. | 12-31-2015 |
David Nguyen, Newton, MA US
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20130138721 | METHOD AND SYSTEM FOR FUND VISUALIZATION - A finds comparison tool is provided that includes a presentation tier providing a plurality of interfaces for interacting with a plurality of client applications. The presentation tier allows the client applications to send requests for a plurality of analytics to be performed regarding comparing the performance of one or more funds or portfolios as well allowing mobile-based client applications and web-based client applications to communicate with the funds comparison tool. An application tier processes the requests sent by the client applications by providing the data used by the client applications, storing and retrieving of session data, and an interface for the analytics information captured during sessions so as to allow a visualization of the analytics used in the comparison of the one or more funds or portfolios. | 05-30-2013 |
David R. Nguyen, Newton, MA US
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20130318007 | LIFETIME INCOME ANALYSIS TOOL - A lifetime income analysis tool (LIAT) that includes a client-based application that provides selective information relating to an individual's retirement. The client-based application processes the selective information to be sent as a request. A server-based application receives the request and processes the request to evaluate the feasibility of an individual's retirement income goal. The server-based application also provides a customized estimate of expected future monthly income needed to cover a broad range of health-care costs in retirement utilizing a plurality of LIAT factors. The server-based application sends its findings as a response to the client-based application for viewing by a user. | 11-28-2013 |
Dieu Nguyen, Wilmington, MA US
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20130324709 | PROCESS FOR THE PREPARATION OF 2-DEOXY-2-FLUORO-2-METHYL-D-RIBOFURANOSYL NUCLEOSIDE COMPOUNDS - An improved process for the preparation of ( | 12-05-2013 |
20140094487 | Dihydro-6-Azaphenalene Derivatives for the Treatment of CNS, Oncological Diseases and Related Disorders - In one embodiment, the present application discloses 2-aza-, 2-oxa- and 2-thia-2,3-dihydro-6-azaphenalene compounds and compositions, and methods for treating a neurological disease in a patient in need thereof using the compounds and compositions as disclosed herein. | 04-03-2014 |
Don Nguyen, Braintree, MA US
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20140244349 | SYSTEM AND METHOD FOR MOBILE ANALYTICS PLATFORM - The disclosed technology, in certain embodiments, provides a mobile analytics platform tailored to a specific industry, e.g., the life science/health care industry. This platform presents large amounts of data, organized and displayed as an analytical story on a portable electronic device. The platform may translate large amounts of data to provide insights and answer questions specific to a user's role. The system may take the user through an analytical story that delivers actionable insights, thus making it easy and intuitive to consume large amounts of information. | 08-28-2014 |
Giang L. Nguyen, Lowell, MA US
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20150317039 | GUI Integrated Request for Enhancement - A computer-assisted method of receiving request for enhancement (RFE) information includes providing, in a product, a graphical user interface (GUI) configured to present to the user one or more inputs for submitting RFE information. The method further includes conveying, by a first processor associated with the product, the RFE information the user submits to the one or more inputs, the RFE information being tagged with an identifier associating the RFE information with the product. The method also includes receiving, by a second processor, the RFE information and the associated identifier, and providing the RFE information and the associated identifier to a service team associated with the product. | 11-05-2015 |
Ha Nguyen, Quincy, MA US
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20110083974 | Method and apparatus for monitoring alteration of flow characteristics in a liquid sample - A device for measuring blood coagulation time is formed from a first substrate; a second substrate; a spacer layer disposed between the first and second substrates, said spacer layer having an opening formed therein defining a sample receiving chamber, a vented sink chamber, and an elongated reservoir forming a conduit for liquid movement between the sample receiving chamber and the sink chamber; a first electrode disposed on the first substrate, said first electrode being exposed in the reservoir portion through a first opening in the spacer layer; and a second electrode disposed on the second substrate, said second electrode being exposed in the reservoir portion through a second opening in the spacer layer. The device of the invention is used in combination with an apparatus that is connected to the first and second electrodes for measuring current flow between the first and second electrodes. Changes in observed current are indicative of flow through the device, and a cessation of flow indicates coagulation. | 04-14-2011 |
20140116894 | Method and apparatus for monitoring alteration of flow characteristics in a liquid sample - A device for measuring blood coagulation time is formed from a first substrate; a second substrate; a spacer layer disposed between the first and second substrates, said spacer layer having an opening formed therein defining a sample receiving chamber, a vented sink chamber, and an elongated reservoir forming a conduit for liquid movement between the sample receiving chamber and the sink chamber; a first electrode disposed on the first substrate, said first electrode being exposed in the reservoir portion through a first opening in the spacer layer; and a second electrode disposed on the second substrate, said second electrode being exposed in the reservoir portion through a second opening in the spacer layer. The device of the invention is used in combination with an apparatus that is connected to the first and second electrodes for measuring current flow between the first and second electrodes. Changes in observed current are indicative of flow through the device, and a cessation of flow indicates coagulation. | 05-01-2014 |
Hanh Nho Nguyen, Arlington, MA US
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20090069297 | Aurora kinase modulators and method of use - The present invention relates to chemical compounds having a general formula I | 03-12-2009 |
20100280008 | AURORA KINASE MODULATORS AND METHOD OF USE - The present invention relates to chemical compounds having a general formula I | 11-04-2010 |
20110201602 | PROTEIN KINASE MODULATORS AND METHOD OF USE - The present invention relates to chemical compounds having a general formula I | 08-18-2011 |
20110251190 | SPIRO-TETRACYCLIC RING COMPOUNDS AS BETA-SECRETASE MODULATORS AND METHODS OF USE - The present invention comprises a new class of compounds useful for the modulation of Beta-secretase enzyme activity and for the treatment of Beta-secretase mediated diseases, including Alzheimer's disease (AD) and other related conditions. In one embodiment, the compounds have a general Formula I | 10-13-2011 |
20110263530 | Aurora Kinase Modulators and Method of Use - The present invention relates to chemical compounds having a general formula I | 10-27-2011 |
20110294837 | Aurora Kinase Modulators and Methods of Use - The present invention relates to chemical compounds having a general formula I | 12-01-2011 |
20120122847 | AURORA KINASE MODULATORS AND METHOD OF USE - The present invention relates to chemical compounds having a general formula I | 05-17-2012 |
20130131035 | CARBOXAMIDES AS INHIBITORS OF VOLTAGE-GATED SODIUM CHANNELS - The present invention provides compounds that are inhibitors of voltage-gated sodium channels (Nav), in particular Nav 1.7, and are therefore useful for the treatment of diseases treatable by inhibition of these channels, in particular, chronic pain disorders. Also provided are pharmaceutical compositions containing such compounds and processes for preparing such compounds. | 05-23-2013 |
20130150339 | Bicyclic Aryl and Heteroaryl Sodium Channel Inhibitors - The present invention provides compounds of Formula I, or pharmaceutically acceptable salts thereof, that are inhibitors of voltage-gated sodium channels, in particular Nav 1.7. | 06-13-2013 |
20140066430 | AURORA KINASE MODULATORS AND METHOD OF USE - The present invention relates to chemical compounds having a general formula I | 03-06-2014 |
20140256707 | Heteroaryl Sodium Channel Inhibitors - The present invention provides compounds of Formula I or II, or pharmaceutically acceptable salts thereof, that are inhibitors of voltage-gated sodium channels, in particular Nav 1.7. The compounds are useful for the treatment of diseases treatable by inhibition of channels such as pain disorders. Also provided are pharmaceutical compositions containing compounds of the present invention. | 09-11-2014 |
20140336182 | Aurora Kinase Modulators and Method of Use - The present invention relates to chemical compounds having a general formula I | 11-13-2014 |
20140371201 | BICYCLIC SULFONAMIDE COMPOUNDS AS SODIUM CHANNEL INHIBITORS - The present invention provides compounds of Formula I, | 12-18-2014 |
20150057271 | DIHYDROBENZOXAZINE AND TETRAHYDROQUINOXALINE SODIUM CHANNEL INHIBITORS - The present invention provides compounds of Formula I, or pharmaceutically acceptable salts thereof, that are inhibitors of voltage-gated sodium channels, in particular Nav 1.7. The compounds are useful for the treatment of diseases treatable by inhibition of sodium channels such as pain disorders. Also provided are pharmaceutical compositions containing compounds of the present invention. | 02-26-2015 |
Han Nho Nguyen, Arlington, MA US
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20090163501 | Aurora kinase modulators and method of use - The present invention relates to chemical compounds having a general formula I | 06-25-2009 |
Hien Nguyen, Northborough, MA US
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20120243520 | LOCATION-BASED ASSOCIATION FOR COMMUNICATIONS NETWORKS - In one implementation, a region descriptor associated with a communications access point and a location descriptor are accessed at a client. The client determines that a location described by the location descriptor is included within a region described by the region descriptor. The client then requests association with the communications access point in response to the determining. | 09-27-2012 |
Hiep T. Nguyen, Boston, MA US
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20130172664 | DEVICE FOR SUPPORTING THE EMPTYING OF THE BLADDER OF A PATIENT AND METHOD FOR OPERATING SUCH A DEVICE - A device for supporting the emptying of the bladder of a patient, the device comprising: an essentially stiff dome-shaped surrounding element for surrounding at least a part of the bladder having a variable volume, the device comprising at least one sensor for detecting the filling level of the bladder, the surrounding element being connectable with the bladder at a lower end of the surrounding element in a fluid-tight manner, so that an inner reservoir is defined in a hollow space between the surrounding element and the wall of the bladder. | 07-04-2013 |
Hiep T. Nguyen, Jamaica Plain, MA US
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20150112240 | DAILYSIS DEVICE - According to one embodiment, a dialysis device is made available that can be implanted at least partially into the body of a patient and comprises a blood chamber, through which the patient's blood can flow, a dialysis chamber for receiving a dialysate, and a hydraulic pump device for compressing the two chambers alternately by means of a hydraulic fluid, wherein both chambers are each equipped with two valves for controlling the inflow and outflow of blood and dialysate, respectively, and wherein both chambers are connected to each other in an area designed as a membrane, | 04-23-2015 |
Hiep Thieu Nguyen, Boston, MA US
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20140253684 | VISUALIZATION OF REGISTERED SUBSURFACE ANATOMY - A system and method for visualization of subsurface anatomy includes obtaining a first image from a first camera and a second image from a second camera or a second channel of the first camera, where the first and second images contain shared anatomical structures. The second camera and the second channel of the first camera are capable of imaging anatomy beneath the surface in ultra-violet, visual, or infra-red spectrum. A data processor is configured for computing registration of the first image to the second image to provide visualization of subsurface anatomy during surgical procedures. A visual interface displays the registered visualization of the first and second images. The system and method are particularly useful for imaging during minimally invasive surgery, such as robotic surgery. | 09-11-2014 |
Huy Q. Nguyen, Dorchester, MA US
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20110053336 | METHOD FOR SELECTIVE DEPOSITION OF DIELECTRIC LAYERS ON SEMICONDUCTOR STRUCTURES - A method for forming a capacitor and a transistor device on different surface portions of a semiconductor structure includes forming a passivation dielectric layer for the device; forming a bottom electrode for the capacitor; forming a removable layer extending over the bottom electrode and over the passivation dielectric layer with a window therein, such window exposing said bottom electrode; depositing a capacitor dielectric layer of the same or different material as the passivation dielectric layer over the removable layer with first portions passing through the window onto the exposed bottom electrode and second portions being over the removable layer, the thickness of the deposited layer being different from the thickness of the passivation layer; removing the removable layer with the second portions thereon while leaving said first portions on the bottom electrode; and forming a top electrode for the capacitor on the second portions remaining on the bottom electrode. | 03-03-2011 |
20160068686 | LONG WAVE INFRARED TRANSPARENT WINDOW AND COATING MATERIALS - Systems and method for forming a nanocomposite material. One example of a nanocomposite material includes a first sulfur-based nanoparticle material defining a first nanophase and a second sulfur-based nanoparticle material defining a second nanophase, wherein the nanocomposite material is at least partially long-wave infrared (LWIR) transmitting, and the first nanophase and the second nanophase are co-dispersed to form interpenetrating networks with one another and each has a grain structure that is distinct from one another. | 03-10-2016 |
Jimmy Nguyen, Lowell, MA US
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20140262446 | SYSTEMS AND METHODS FOR PROVIDING SURFACE CONNECTIVITY OF ORIENTED CONDUCTIVE CHANNELS - An electrically conductive composite is disclosed that includes a dielectric material having a first side and a second side, conductive particles within the dielectric material layer, and a discontinuous layer of a conductive material on a first side of the dielectric layer. The conductive particles are aligned to form a plurality of conductive paths from the first side to the second side of the dielectric material, and each of the conductive paths is formed of at least a plurality of conductive particles. The discontinuous layer includes a plurality of non-mutually connected portions that cover portions of, but not all of, the first side of the dielectric material such that exposed portions of the underlying first side of the dielectric material remain exposed through the discontinuous layer, yet the discontinuous layer facilitates the electronic coupling together of a plurality of the conductive paths from the first side to the second side of the dielectric material. | 09-18-2014 |
20150282312 | SYSTEMS AND METHODS FOR PROVIDING SURFACE CONNECTIVITY OF ORIENTED CONDUCTIVE CHANNELS - An electrically conductive composite is disclosed that includes a dielectric material having a first side and a second side, conductive particles within the dielectric material layer, and a discontinuous layer of a conductive material on a first side of the dielectric layer. The conductive particles are aligned to form a plurality of conductive paths from the first side to the second side of the dielectric material, and each of the conductive paths is formed of at least a plurality of conductive particles. The discontinuous layer includes a plurality of non-mutually connected portions that cover portions of, but not all of, the first side of the dielectric material such that exposed portions of the underlying first side of the dielectric material remain exposed through the discontinuous layer, yet the discontinuous layer facilitates the electronic coupling together of a plurality of the conductive paths from the first side to the second side of the dielectric material. | 10-01-2015 |
Jonathan K. Nguyen, Rockland, MA US
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20100061897 | Microencapsulation of amines - A system for microencapsulation of an amine in a polymer shell in an aqueous environment. | 03-11-2010 |
Jonathan Kim Nguyen, Lexington, MA US
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20110286080 | ELECTROPHORETIC MEDIA, AND MATERIALS FOR USE THEREIN - An electrophoretic medium comprises a continuous phase and a discontinuous phase. The discontinuous phase comprises a plurality of droplets, each of which comprises a fluid and at least one charged particle disposed within the fluid and capable of moving through the fluid upon application of an electric field to the electrophoretic medium. The continuous phase surrounds and encapsulates the discontinuous phase and comprising a polymeric binder and a salt, the salt having an anion containing at least one fluorine atom and having a water solubility of at least about 0.25 per cent by weight at 25° C. | 11-24-2011 |
Khiem Nguyen, Tewksbury, MA US
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20080303703 | Cross-Coupled Switched Capacitor Circuit with a Plurality of Branches - A cross-coupled switched capacitor circuit that has two branches. During a first phase for the first branch, an input voltage is provided that causes charge to move through a resistor and to be placed onto a plate of the capacitor within the branch. An equivalent amount of charge is transferred to an output node. The output node may be a summing node of a sigma-delta modulator. The summing node is one of the inputs to an operational amplifier that is part of the integrator of the sigma-delta modulator. The resistor and the capacitor in the first branch define an RC circuit and corresponding RC time constant. During the first phase, the capacitor does not reach a fully settled voltage for a desired resolution. During the second phase, the capacitor in the first branch of the circuit is set to a defined voltage. The defined voltage may be the settling voltage had the capacitor been allowed to settle during the first phase. The second branch of the switched capacitor feedback circuit operates similar to the first branch, but on opposite phases. By not requiring the voltage to settle during the first phase, power can be conserved, since the integrator of the sigma-delta modulator does not need to operate as fast with respect to movement of charge. | 12-11-2008 |
20090102551 | OPERATIONAL AMPLIFIER WITH IMPROVED CURRENT MONITORING AND SCALABLE OUTPUT - A low-power, low-voltage feedback class AB operational amplifier is disclosed. The minimum supply voltage is one gate-source voltage and two saturation voltages. Currents on the output p-type and n-type transistors are monitored as part of the feedback loop control. Accurate monitoring is achieved by connecting current monitors directly to the corresponding voltage rail. Additional output stages may be selectively connected to the primary output stage to dynamically adjust to changes source conditions. Thus by connecting the appropriate number and type of additional output stages, continuous time adaptive power supply compensation is achieved. Both single ended and differential topologies are described. | 04-23-2009 |
Khiem Quang Nguyen, Tewksbury, MA US
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20100149012 | SYSTEM AND METHOD FOR AREA-EFFICIENT THREE-LEVEL DYNAMIC ELEMENT MATCHING - A system for converting digital signals into analog signals using sigma-delta modulation and includes a signed thermometer encoder for converting a plurality of signed binary data received at the encoder into a plurality of signed thermometer data and a rotational dynamic element matching (DEM) arrangement for receiving the plurality of signed binary data and the plurality of signed thermometer data. The rotational DEM arrangement further includes a first barrel shifter for receiving a positive thermometer data at a cycle, the first barrel shifter having a first pointer indicating a starting position of next positive thermometer data, and a second barrel shifter for receiving a negative thermometer data at a cycle, the second shifter having a second pointer indicating a starting position of next negative thermometer data, wherein the first pointer is circularly shifted as a function of positive binary data and the second pointer is circularly shifted as a function of negative binary data. | 06-17-2010 |
20120286859 | INPUT COMMON MODE VOLTAGE COMPENSATION CIRCUIT - A voltage level shifter for a direct coupling of an external voltage source to a common mode of a circuit may include an amplifier, a voltage-controlled current source, a first and second resistors. A first input of the amplifier may be connected to the common mode. A second input of the amplifier may, via the first and second resistors, receive a voltage indicative of the external voltage source. The output of the amplifier may indicate a voltage difference between the first and second inputs. The voltage-controlled current source may be controlled by the voltage difference to supply a current to a common node of the first and second resistors so that the voltage difference between the first and second inputs may be minimized. | 11-15-2012 |
20120313676 | HYBRID DIGITAL-ANALOG PHASE LOCKED LOOPS - A digital PLL may be combined with an analog PLL so that the output of the digital PLL is at a frequency high enough to maintain stability in the analog PLL when an initial reference clock signal is too low to maintain stability in the analog PLL. The digital PLL may include a scaling circuit, such as a frequency divider in the feedback path of the PLL, to generate the higher frequency output signal from the lower frequency reference input signal. The digital PLL may also use an on-chip free run ring oscillator as the clock for the digital PLL engine. | 12-13-2012 |
20120314874 | TWO-WIRE DIGITAL AUDIO INTERFACE - A digital audio interface may include two signal inputs to transmit audio data. A first signal line may carry digital serial audio data. The second signal line may carry a word clock signal to differentiate the serial audio data transmitted over the first signal line. In the case of stereo audio data, the word clock signal may correspond to a left-right clock signal and may differentiate audio data intended for a right channel from that intended for a left channel. The audio data may also be differentiated differently depending on the configuration, such as in the case that the transmitted audio data include audio for more than two channels. The word clock signal may be scaled to regenerate a bit clock signal used to encode the serial audio data over the first signal line. The encoding bit clock signal need not be transmitted. | 12-13-2012 |
20130207665 | SENSOR FAULT DETECTION SYSTEM AND METHOD - Fault detection techniques for control of sensor systems. A sensor control integrated circuit (“IC”) may include a fault detection system for coupling to the sensor supply lines. The system may detect faults for each of the sensor supply lines. The fault detection system may level shift sensor supply line signals from a first voltage domain to a second voltage domain appropriate for the fault detection system of the controller IC. The fault detection system may level shift source potential voltages from the first voltage domain to the second voltage domain to detect predetermined fault types. The fault detection system may compare the second domain voltages from the sensor supply lines to voltages representing predetermined fault types and may generate fault status indicators based on the comparison. | 08-15-2013 |
20130218512 | METHOD AND APPARATUS FOR LOW COST, HIGH ACCURACY TEMPERATURE SENSOR - The invention may provide a temperature sensor device that includes an analog temperature sensor to generate a first base-emitter voltage and a second base-emitter voltage, and an analog-to-digital converter (ADC) to sample at the voltages and generate corresponding digital values. The temperature sensor device may also include a logic unit to calculate a digital temperature code from the digital values using a digital virtual reference. | 08-22-2013 |
20140152480 | ENHANCED SECOND ORDER NOISE SHAPED SEGMENTATION AND DYNAMIC ELEMENT MATCHING TECHNIQUE - A method and circuit to perform noise shaped splitting of a digital input signal may include using multiple layers to process the input signal. In the first layer, the most significant bits of the input signal may be distributed to a plurality of branches. Dynamic element matching may be performed using the least significant bits of the input signal. Based on the results of the dynamic element matching, values may be added to the plurality of branches. If there is insufficient data activity, dynamics enhancement may be performed to increase the data activity. The output signals of each of the plurality of branches in the first layer may be provided to a second layer, in which these steps can be repeated on each of the output signals. The outputs of the second layer may be provided to a plurality of three level unit elements. | 06-05-2014 |
20150028835 | AREA-EFFICIENT FREQUENCY COMPENSATION - A DC-to-DC converter includes an error integrator that further includes a first amplifier and a second amplifier that each includes a first input for receiving a reference voltage and a second input for receiving a feedback voltage, a capacitor to an output of the second amplifier, and a resistor including a first end being coupled to an output of the first amplifier and a second end being coupled to the capacitor. | 01-29-2015 |
20150281836 | TRANSDUCER AMPLIFICATION CIRCUIT - A transducer amplification circuit may include a preamplifier circuit with a signal input receiving a transducer signal to provide an amplified transducer signal comprising audible frequency components and ultrasonic frequency components. The transducer amplification circuit may include a first sigma-delta modulator configured to sample and quantize the amplified transducer signal to generate a first digital transducer signal comprising a first quantization noise signal. The first sigma-delta modulator may include a first noise transfer function having a high pass response in at least a portion of an audible frequency range to push the quantization noise signal to ultrasonic frequencies. A second sigma-delta modulator is configured to sample and quantize the amplified transducer signal to generate a second digital transducer signal comprising a second quantization noise signal. The second sigma-delta modulator may include a second noise transfer function with a magnitude minimum placed at the ultrasonic frequencies. | 10-01-2015 |
Lang H. Nguyen, Lowell, MA US
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20150087764 | Oxidized Carbon Blacks Treated with Polyetheramines and Coating Compositions Comprising Same - Disclosed herein are materials and compositions comprising: an oxidized carbon black having a BET surface area ranging from 50 to 700 m2/g, a DBP oil adsorption number ranging from 50 to 200 mL/100 g, and a primary particle size ranging from 7 to 30 nm; and a polyetheramine comprising ethylene oxide and propylene oxide monomers, wherein the polyetheramine coats the oxidized carbon black. Also disclosed are coatings and coating compositions comprising these materials and methods of making the same. | 03-26-2015 |
20160024345 | Oxidized Carbon Blacks Treated with Polyetheramines and Coating Compositions Comprising Same - Disclosed herein are materials and compositions comprising: an oxidized carbon black having a BET surface area ranging from 50 to 700 m | 01-28-2016 |
Le Nguyen, Dorchester, MA US
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20130126620 | MODULAR CHEMISTRY ANALYZER - Disclosed in one general aspect is a modular chemistry analysis test unit for a chemistry analyzer that includes one or more vessels for one or more reagents. A machine-readable test specification is coupled with the vessels and identifies a series of test operations that employ the reagents for the vessels. The specification includes one or more reagent quantity specifications that specify a quantity of the reagents to mix with a test sample, and one or more reaction duration specifications that specify a reaction time for the reagents and test sample. | 05-23-2013 |
20130130390 | MODULAR CHEMISTRY ANALYZER - An automated chemistry analysis method is disclosed. In one general aspect, the method includes receiving a modular chemistry analysis test unit that includes one or more vessels for one or more reagents, and a machine-readable test specification coupled with the vessels. The method also includes defining a test that defines a test including a series of operations that employ the reagents for the vessels, and installing the chemistry analysis test unit in a first chemistry analyzer that includes one or more analysis tools and sequencing logic for sequencing instructions to be carried out by the analysis tools. The machine-readable test specification is automatically received from the chemistry analysis test module and stored for access by the sequencing logic to allow the sequencing logic to instruct the analysis tools to carry out the test defined by the test specification. | 05-23-2013 |
20130132882 | MODULAR CHEMISTRY ANALYZER - Disclosed in one general aspect is a method of operating a chemistry analyzer method that includes determining usage levels associated with a plurality of storage vessels that store reagents for use by the analyzer. A pictorial representation that includes a plurality of graphical elements that convey levels of usage for the storage vessels is displayed to the operator. A series of access icons that are each associated with a color and each lead to a set of screens for different types of operations for the analyzer are also displayed, with the screens being color coded to correspond to the color associated with their respective access icons. | 05-23-2013 |
Linh Tuong Nguyen, Randolph, MA US
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20110112576 | Tissue Repair Devices - The present disclosure relates to an anchor assembly. The anchor assembly includes an anchor defining a cavity and an opening to the cavity; and a headless insertion member configured for arrangement within the anchor cavity, the insertion member including a body having a threaded proximal portion, a non-threaded distal portion, and a cannulation extending a partial length of the insertion member. Other anchor assemblies, anchors, and delivery devices are also disclosed. | 05-12-2011 |
20120271323 | SUTURE PASSER WITH SUTURE CAPTURING ARTICULATING JAW AT DISTAL END FOR SUTURING IN ARTHROSCOPIC SURGERY - A suture passer including a tubular member having a proximal end and a distal end and a central axis defined therethrough, in which the tubular member includes at least one lumen formed therein, an eyelet configured to receive a suture, a movable jaw formed on the distal end of the tubular member configured to move between an open position and a closed position, in which the movable jaw includes a plurality of portions, and an actuator configured to be received within the at least one lumen of the tubular member, in which the actuator is configured to move along the central axis of the tubular member between a first position and a second position, in which, in the first position, the movable jaw is in the closed position, and in which, in the second position, the movable jaw is in the open position. | 10-25-2012 |
Lonnissa Nguyen, Cambridge, MA US
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20110262493 | MULTI-LAYERED HYDROGEL CONSTRUCTS AND ASSOCIATED METHODS - Multi-layered hydrogel constructs comprising: a first layer comprising a first polymerizable material, hyaluronic acid and a plurality of cells; a second layer comprising a second polymerizable material, chondroitin sulfate and a plurality of cells; and a third layer comprising a third polymerizable material, chondroitin sulfate, a matrix metalloprotease sensitive peptide, and a plurality of cells are provided. Associated methods are also provided. | 10-27-2011 |
Man Nguyen, West Roxbury, MA US
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20120172662 | Snare with Retractable Engaging Members - A snare for retrieving foreign objects within the body of a patient including a hollow elongate tubular member comprising an inner surface and an outer surface and a lumen defined by the inner surface, a proximal end and a distal end, the hollow elongate tubular member forms a loop at the distal end, the loop having an open position and a closed position, the loop comprising at least one opening and a wire slidably disposed in the lumen of the elongate tubular member, the wire comprising at least one engaging member for engaging tissue, the at least one engaging member extends through the at least one opening in the hollow elongate tubular member when the wire is in a first position and the at least one engaging member retracts into the lumen of the elongate tubular member when the wire moved to a in a second position. | 07-05-2012 |
20130018384 | Medical Retrieval and Capture Device and Related Methods of Use - A medical device and related methods of use are provided for capture and removal of tissue from body lumens. The device includes an end-effector unit configured to capture tissue, having a distal end and a proximal end. The distal end and the proximal end form a substantially closed structure, and the distal end is more flexible than the proximal end. The device also includes a control member at the proximal end for holding and controlling the severing device. | 01-17-2013 |
20130110109 | MUCOSAL RESECTION DEVICE AND RELATED METHODS OF USE | 05-02-2013 |
20130172828 | ENDOSCOPIC GUIDE WIRE TRACK - A medical device may include an end effector configured to perform a therapeutic procedure. The medical device may further include a guide having a modifiable shape. The guide may be adapted for insertion through a lumen of an access tube. Also, the end effector may be selectively attachable to the guide and configured to move along the guide. | 07-04-2013 |
Man M. Nguyen, Harvard, MA US
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20160066935 | RETRIEVAL DEVICES AND RELATED METHODS OF USE - According to aspects of the present disclosure, a retrieval device may include a sheath, a first drive member in the sheath, and a second drive member in the sheath. The second drive member may be movable relative to the first drive member. An end effector may be retractable into and extendable out of the sheath. The end effector may include a first proximal end portion coupled to the first drive member, a second proximal end portion coupled to the second drive member, and a plurality of legs extending distally from the first and second proximal end portions to a distal tip of the end effector. All of the legs that extend to the distal tip may be fixed together at the distal tip. | 03-10-2016 |
Man M. Nguyen, West Roxbury, MA US
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20130110090 | ROTATABLE MEDICAL DEVICE | 05-02-2013 |
Man Minh Nguyen, Harvard, MA US
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20140364926 | DEVICES FOR DELIVERING ENERGY AND RELATED METHODS OF USE - A medical device is disclosed. The medical device may include an elongate member having a lumen extending at least partially between a proximal end and a distal end of the elongate member. The medical device may also include a plurality of legs coupled to a distal portion of the elongate member, and a distal end piece connected to each of the plurality of legs and located distally to the distal end of the elongate member. The medical device may also include an actuating member coupled to the distal end piece and extending between the plurality of legs and through the lumen. The reciprocal movement of the actuating member may be configured to reversibly move the plurality of legs from a first position to a second position. The medical device may also include a stopping member coupled to the actuating member and configured to limit a movement of the actuating member. | 12-11-2014 |
20150045788 | EXPANDABLE CATHETER AND RELATED METHODS OF MANUFACTURE AND USE - A medical device may include an expandable energy delivery array reciprocally movable between a first configuration and a second configuration. The expandable energy delivery array may include a first assembly having a first proximal end piece, a first distal end piece, and one or more first energy transfer elements extending between the first proximal and first distal end pieces, and a second assembly having a second proximal end piece, a second distal end piece, and one or more second energy transfer elements extending between the second proximal and second distal end pieces. The second proximal end piece may be proximal to the first proximal end piece and the second distal end piece may be distal to the first distal end piece. | 02-12-2015 |
20150265283 | DEVICES AND METHODS FOR LUMEN OCCLUSION - Methods and devices for at least partially occluding an airway of a lung is disclosed. The method includes deploying a catheter into the airway such that a balloon at a distal end of the catheter is positioned proximate a tissue wall that defines the airway, and inflating the balloon to cause pressure to be applied on a portion of the tissue wall. The method may also include deflating the balloon to cause the portion of the tissue wall to be drawn radially inward to at least partially occlude the airway. | 09-24-2015 |
20150265331 | DEVICES FOR REDUCING LUNG VOLUME AND RELATED METHODS OF USE - A method for isolating a portion of a lung may include inserting a treatment device into an airway of a patient, and applying energy from the treatment device to a treatment site in the airway to at least partially occlude the airway to inhibit air from entering the airway distal to the treatment site. | 09-24-2015 |
20150265799 | DEVICES AND METHODS FOR TREATING A LUNG - Methods and devices for treating a lung are disclosed. The method may include deploying a catheter into an airway of the lung, and discharging a media into the airway through the catheter. The media may be configured to increase elasticity of lung tissue in the vicinity of the airway or occlude the airway. | 09-24-2015 |
20150272591 | DEVICES AND METHODS FOR MODIFYING A VOLUME OF A CAVITY - Exemplary embodiments of a method for assisting breathing in a lung having damaged tissue are disclosed. The method may include inserting an implant containing a dilatant fluid into a pleural cavity of a patient to reduce an inhalation volume of the lung. Additional embodiments may include an implant configured to apply a force toward a portion of a lung. A controller may be coupled to the implant and configured to sense a biological event and control an amount of outwardly directed force applied by the implant to the lung in response to the biological event. Further, a method may include applying a force to an organ via an implant to expel material from the organ and adjusting the implant so as to transition between a first configuration and a second configuration. The implant may include at least one of an electro-active material and a pressure sensitive material. | 10-01-2015 |
20160058464 | MUCOSAL RESECTION DEVICE AND RELATED METHODS OF USE - A resection device for resecting tissue from a body. The device includes an elongate member having a proximal end, a distal end, and a lumen extending from the proximal end to the distal end. The device further includes a cap assembly configured | 03-03-2016 |
Minh Nguyen, Dorchester Center, MA US
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20120289694 | L-PROLINE AND CITRIC ACID CO-CRYSTALS OF (2S,3R,4R,5S,6R)-2-(3-((5-(4-FLUOROPHENYL)THIOPHEN-2-YL)METHYL)-4-METHYLP- HENYL)-6-(HYDROXYMETHYL)TETRAHYDRO-2H-PYRAN-3,4,5-TRIOL - The present invention is directed to L-proline and citric acid co-crystals of (2S,3R,4R,5S,6R)-2-(3-((5-(4-fluorophenyl)thiophen-2-yl)methyl)-4-methylphenyl)-6-(hydroxymethyl)tetrahydro-2H-pyran-3,4,5-triol, pharmaceutical compositions containing said co-crystals and their use in the treatment glucose-related disorders such as Type 2 diabetes mellitus and Syndrome X. | 11-15-2012 |
Minh Ngoc Nguyen, Dorchester, MA US
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20150072986 | UREA DERIVATIVES AND USES THEREOF - The present invention provides novel compounds of any one of Formulae (I)-(III), and pharmaceutical compositions thereof. Also provided are particles (e.g., nanoparticles) comprising compounds of Formula (I)-(III) and pharmaceutical compositions thereof that are mucus penetrating. The invention also provides methods and kits for using the inventive compounds, and pharmaceutical compositions thereof, for treating and/or preventing diseases associated with abnormal or pathological angiogenesis and/or aberrant signaling of a growth factor (e.g., vascular endothelial growth factor (VEGF)), such as proliferative diseases (e.g., cancers, benign neoplasms, inflammatory diseases, autoimmune diseases) and ocular diseases (e.g., macular degeneration, glaucoma, diabetic retinopathy, retinoblastoma, edema, uveitis, dry eye, blepharitis, and post-surgical inflammation) in a subject in need thereof. | 03-12-2015 |
Mint Ngoc Nguyen, Dorchester, MA US
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20150125535 | CRYSTALLINE FORMS OF THERAPEUTIC COMPOUNDS AND USES THEREOF - Described herein is certain crystalline forms of Compound 3, as well as pharmaceutical compositions employing the crystalline forms. Also provided are particles (e.g., nanoparticles) comprising such crystalline forms or pharmaceutical compositions. In certain examples, the particles are mucus penetrating particles (MPPs). The present invention further relates to methods of treating or preventing diseases using crystalline forms or pharmaceutical compositions. | 05-07-2015 |
Nam Nguyen, Everett, MA US
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20120266967 | EVAPORATOR - A solid precursor delivery assembly generally includes a container having upper and lower portions and chambers defined within the container, including an inlet chamber, an outlet chamber, and first and second precursor chambers. The first and second precursor chambers are configured for holding precursor material within the container. Sintered frits are fixedly coupled and sealed to an interior portion of the container, and define at least part of the chambers within the container. At least one of the sintered frits is configured for retaining precursor material thereon within the first precursor chamber, and at least one of the sintered frits is configured for retaining precursor material thereon within the second precursor chamber. An inlet is coupled to the container for delivering carrier gas into the container, and an outlet is coupled to the container for use in removing vaporized precursor material and carrier gas from the container. | 10-25-2012 |
Nam Hoang Nguyen, Lowell, MA US
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20110213761 | SEARCHABLE WEB SITE DISCOVERY AND RECOMMENDATION - A searchable web site discovery and recommendation system and method for discovering and recommending searchable web sites to a user of a search engine. In general, given a search query by a user embodiments of the system and method discover and then recommend a list of searchable web sites. Embodiments of the system and method discover and recommend searchable web sites using client-side query behavior logs. A set of descriptive features is automatically extracted from the logs. In addition, embodiments of the system and method expand the initial search query by submitting the query to a general search engine and leveraging snippets from the search engine results. Embodiments of the system and method model a conditional probability of a searchable web site based on four components and the extracted descriptive features. A ranked list of recommended searchable web sites is obtained from the conditional probability and displayed to a user. | 09-01-2011 |
Ngan Nguyen, Somerville, MA US
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20140162983 | Compositions and Methods for the Production of Pyrimidine and Pyridine Compounds with BTK Inhibitory Activity - The present invention provides novel pyrimidine and pyridine compounds according to Formula (I), Formula (II), Formula (III), Formula (IV) and Formula (V) their manufacture and use for the treatment of hyperproliferative diseases including, but not limited to, cancer, lupus, allergic disorders, Sjogren's disease and rheumatoid arthritis. In preferred embodiments, the present invention describes irreversible kinase inhibitors including, but not limited to, inhibitors of Bruton's tyrosine kinase. | 06-12-2014 |
Ngan Nguyen, Arlington, MA US
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20150259363 | COMPOSITIONS AND METHODS FOR THE PRODUCTION OF PYRIMIDINE AND PYRIDINE COMPOUNDS WITH BTK INHIBITORY ACTIVITY - The present invention provides novel pyrimidine and pyridine compounds according to Formula (I), Formula (II), Formula (III), Formula (IV) and Formula (V) their manufacture and use for the treatment of hyperproliferative diseases including, but not limited to, cancer, lupus, allergic disorders, Sjogren's disease and rheumatoid arthritis. In preferred embodiments, the present invention describes irreversible kinase inhibitors including, but not limited to, inhibitors of Bruton's tyrosine kinase. | 09-17-2015 |
Nguyen D. Nguyen, Dorchester, MA US
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20090243912 | Automotive Radar Sensor Blockage Detection System and Related Techniques - A blockage detection system and method for use in a sensor such as a side object detection (SOD) sensor in an automotive radar system is described. The sensor emits signals and receives return signals (i.e. reflected signals) from a passing object. If the passing object is within a virtual detection zone, the sensor uses the information from the passing object to determine if a blockage condition exists in the sensor. The technique utilizes statistics related to the passing object to determine whether a blockage condition exists within the sensor. In one embodiment, a SOD sensor mounted in a first vehicle uses information from a second passing vehicle (e.g. radar return information) to determine whether a blockage condition exists within the SOD sensor itself. | 10-01-2009 |
Nhat Khai L. Nguyen, Boston, MA US
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20150044664 | DEVICE AND METHOD FOR CONTROLLING THE TEMPERATURE IN A MOVING FLUID IN A LABORATORY SAMPLE PROCESSING SYSTEM - A temperature control device and method are provided for an analytical system for performing laboratory protocols. The device includes a well within a housing configured to receive a biological specimen according to a predetermined sample process. The specimen is suspended by a holding device in the well. A thermal element is provided in heat exchange communication with fluid in the well. A temperature sensor is located in the well at a location to be covered and uncovered by rocking motion of fluid in the well. A controller, in communication with the thermal element, the temperature sensor, and an agitation system, is operative to control the thermal element in correlation with temperature data, for example, peak temperature data, from the temperature sensor. | 02-12-2015 |
Nhung Nguyen, Westford, MA US
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20110098267 | TOPICAL FORMULATIONS FOR THE TREATMENT OF PSORIASIS - The invention relates to a topical composition and a method for treating psoriasis. The topical composition comprises one or more compound that inhibits the production of IL-12 and IL-23. | 04-28-2011 |
Peter Q. Nguyen, Boston, MA US
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20110287462 | PROTEIN FRAGMENT COMPLEMENTATION ASSAY FOR THERMOPHILES - A protein fragment complementation assay for thermophiles is provided wherein a thermophilic bacteria having a temperature-sensitive adenylate kinase is transformed with one or more vectors having sequences encoding a first test peptide operatively fused to a first portion of a thermostable adenylate and a second test peptide operatively fused to a second portion of the thermostable adenylate kinase. Association of the first and second test peptides allows association of the first and second portions of the thermostable adenylate kinase and growth of the thermophilic bacteria at a temperature greater than 70° C. | 11-24-2011 |
Phu C. Nguyen, Cambridge, MA US
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20110305909 | ARTICLES HAVING NON-FOULING SURFACES AND PROCESSES FOR PREPARING THE SAME WITHOUT ALTERING BULK PHYSICAL PROPERTIES - Processes are described herein for preparing medical devices and other articles having a low-fouling surface on a substrate comprising a polymeric surface. The polymeric surface material may possess a range of polymeric backbones and substituents while providing the articles with a highly efficient, biocompatible, and non-fouling surface. The processes involve treating the substrate to reduce the concentration of chemical species on the surface of or in the substrate without altering the bulk physical properties of the device or article, and thereafter forming a grafted polymer layer on the treated substrate surface. | 12-15-2011 |
20130158518 | SURFACE MODIFICATION FOR CATHETERS COMPRISED OF MULTIPLE MATERIALS - Catheters and a method for preparation thereof, the catheter comprising as component parts thereof a catheter body, a juncture hub, at least one extension line and at least one connector, each of said component parts comprising an exterior surface, at least one lumen having an intraluminal surface and a bulk polymer, wherein the intraluminal or external surface of a first of said component parts and the exterior or intraluminal surface of a second of said component parts comprise a hydrophilic polymer layer thereon having an Average Dry Thickness of at least about 50 nanometers and the first and second component parts comprise bulk polymers having different chemical compositions | 06-20-2013 |
Phuong Nguyen, Cambridge, MA US
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20090325903 | BORONATE ESTER COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS THEREOF - The present invention provides novel compounds useful as proteasome inhibitors. The invention also provides pharmaceutical compositions comprising the compounds of the invention and methods of using the compositions in the treatment of various diseases. | 12-31-2009 |
20110130327 | Multi-Arm Amines and Uses Thereof - Multi-arm amine compounds and compositions for enhancing intracellular, in vitro, and in vivo delivery of drug, active, and therapeutic substances including ribonucleic acids. This disclosure provides novel compounds and compositions for making and using delivery materials and carriers which increase the efficiency of delivery of biologically active and pharmacologically active molecules. Embodiments of this disclosure may further provide delivery of various therapeutic agents including nucleic acid therapeutics such as regulatory RNA, interfering RNA, and agents for RNAi, as well as other protein and peptide therapeutics. In some aspects, this disclosure provides multi-arm amine compounds and compositions which can enhance permeation of a drug substance. | 06-02-2011 |
Phuong M. Nguyen, Cambridge, MA US
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20130165390 | BORONATE ESTER COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS THEREOF - The present invention provides novel compounds useful as proteasome inhibitors. The invention also provides pharmaceutical compositions comprising the compounds of the invention and methods of using the compositions in the treatment of various diseases. | 06-27-2013 |
20140018301 | BORONATE ESTER COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS THEREOF - The present invention provides novel compounds useful as proteasome inhibitors. The invention also provides pharmaceutical compositions comprising the compounds of the invention and methods of using the compositions in the treatment of various diseases. | 01-16-2014 |
20140341885 | FORMULATION FOR ANTI-ALPHA4BETA7 ANTIBODY - Antibody formulations are described comprising a mixture of an anti-α4β7 antibody, an antioxidant or chelator, and at least one free amino acid. The disclosed formulations may have improved stability, reduced aggregate formation, or both. The present invention further provides a safe dosing regimen of these antibody formulations that is easy to follow, and which results in a therapeutically effective amount of the anti-α4β7 antibody in vivo. | 11-20-2014 |
20140343314 | BORONATE ESTER COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS THEREOF - The present invention provides novel compounds useful as proteasome inhibitors. The invention also provides pharmaceutical compositions comprising the compounds of the invention and methods of using the compositions in the treatment of various diseases. | 11-20-2014 |
20140349966 | BORONATE ESTER COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS THEREOF - The present invention provides novel compounds useful as proteasome inhibitors. The invention also provides pharmaceutical compositions comprising the compounds of the invention and methods of using the compositions in the treatment of various diseases. | 11-27-2014 |
20150307523 | BORONATE ESTER COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS THEREOF - The present invention provides novel compounds useful as proteasome inhibitors. The invention also provides pharmaceutical compositions comprising the compounds of the invention and methods of using the compositions in the treatment of various diseases. | 10-29-2015 |
20160031913 | BORONATE ESTER COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS THEREOF - The present invention provides novel compounds useful as proteasome inhibitors. The invention also provides pharmaceutical compositions comprising the compounds of the invention and methods of using the compositions in the treatment of various diseases. | 02-04-2016 |
Si Nguyen, Winchester, MA US
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20140286256 | SYSTEMS AND METHODS FOR SCHEDULING OF DATA PACKETS BASED ON DELAY TOLERANCE OF APPLICATIONS - A base station, system, method, and computer program product are disclosed for transmitting data packets received by the base station. According to one aspect, the base station includes a first buffer configured to store data packets received by the base station, a second buffer configured to store data packets that are scheduled for transmission by the base station, and a computer processor, operatively coupled to the first buffer and the second buffer. The computer processor is configured to inspect a data packet to determine an application type of the data packet, determine a delay tolerance associated with the data packet based on the determined application type, determine a channel condition of a communication session with the user device, move the data packet from the first buffer to the second buffer based on the determined delay tolerance and the determined channel condition, and transmit data packets stored in the second buffer. | 09-25-2014 |
20150341941 | Enhanced Inter-Cell Interference Coordination - A system, a method, and a computer program product for providing an enhanced inter-cell interference coordination. Information indicating at least one almost blanking subframe (ABS) being allocated is being exchanged by at least two cells in a wireless network. Based on the allocated ABS, the devices further exchange information indicating a wireless signal throughput. | 11-26-2015 |
Son T. Nguyen, Cambridge, MA US
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20140031562 | Method for Forming Allylic Alcohols - A method of performing a chemical reaction includes reacting an allyl donor and a substrate in a reaction mixture, and forming a homoallylic alcohol in the reaction mixture. The substrate may be an aldehyde or a hemiacetal. The reaction mixture includes a ruthenium catalyst, carbon monoxide at a level of at least 1 equivalent relative to the substrate, and water at a level of at least 1 equivalent relative to the substrate, and an amine at a level of from 0 to 0.5 equivalent relative to the substrate. The reaction mixture may also include a halide, and the equivalents of the amine may be similar to those of the halide. The reacting includes maintaining the reaction mixture at a temperature of at least 40° C. The method may be catalytic in metal, environmentally benign, amenable to large-scale applications, and applicable to a wide range of substrates. | 01-30-2014 |
Steve Nguyen, Cambridge, MA US
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20130085264 | Methods and Reagents for Diagnosing Hantavirus Infection - Novel methods and immunodiagnostic test kits for the detection of hantavirus infection are disclosed. The methods and kits employ combinations of recombinant N and/or G1 antigens from at least six different hantavirus serotypes, including Hantann (HTNV), Puumala (PUUV), Seoul (SEOV), Dobrava (DOBV), Sin Nombre (SNV) and Andes (ANDV). Additional hantavirus antigens from these and other hantavirus types may also be present. The methods provide for highly accurate results and allow the detection of infection so that treatment can be administered and death avoided. | 04-04-2013 |
Steven D. Nguyen, Lowell, MA US
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20140111373 | Calibration System and Technique For A Scalable, Analog Monopulse Networks - Described is a calibration technique for an Active Electronically Scanned Array (AESA) having a scalable, analog monopulse network. | 04-24-2014 |
Tam Nguyen Thuc Nguyen, Cambridge, MA US
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20160043800 | DESIGN OF A FREE-SPACE OPTICAL COMMUNICATION MODULE FOR SMALL SATELLITES - Communication bottlenecks, particularly in the downlink direction, are a common problem for many CubeSat developers. As described herein, a CubeSat module for a CubeSat comprises an optical transmitter to transmit data to a remote terminal, a receiver to acquire an optical beacon from a remote terminal, and a fine-pointing module operably and directly coupleable to a coarse-pointing module of the CubeSat. The fine-pointing module is configured to point the optical transmitter toward the remote terminal with an accuracy range that overlaps with an accuracy range of the coarse-pointing module of the CubeSat so as to establish a communications link between the CubeSat and the remote terminal over a low-Earth-orbit (LEO) distance. | 02-11-2016 |
Thang D. Nguyen, Lawrence, MA US
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20160087557 | SYSTEM AND METHOD FOR ELECTROSTATIC CLAMPING OF WORKPIECES - A system and method for clamping a workpiece to an electrostatic clamp (ESC) comprises placing a first workpiece on a surface of the ESC and applying a first set of clamping parameters to the ESC, therein clamping the first workpiece to the surface of the ESC with a first clamping force. A degree of clamping of the workpiece to the ESC is determined and the application of the first set of clamping parameters to the ESC is halted based on a process recipe. A second set of clamping parameters is applied to the ESC after halting the application of the first set of clamping parameters to the ESC, and the workpiece is removed from the surface of the ESC concurrent with the application of the second set of clamping parameters to the ESC when the degree of clamping of the workpiece to the ESC is less than or approximately equal to a threshold clamping value. The second set of clamping parameters to the ESC is further halted after removing the workpiece from the surface of the ESC. | 03-24-2016 |
Thinh Nguyen, Medford, MA US
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20120271305 | MULTIFUNCTION MEDICAL DEVICE AND RELATED METHODS OF USE - An embodiment of the invention may include a medical device. The medical device may include a flexible tube, an elongate member configured to cut tissue and extend from the flexible tube, and a cauterizing member configured to cauterize tissue and to move relative to the elongate member and the flexible tube. The cauterizing member may substantially surround at least a portion of the elongate member. | 10-25-2012 |
Thinh D. Nguyen, Meford, MA US
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20140114125 | MULTIFUNCTION MEDICAL DEVICE AND RELATED METHODS OF USE - An embodiment of the invention may include a medical device. The medical device may include a flexible tube, an elongate member configured to cut tissue and extend from the flexible tube, and a cauterizing member configured to cauterize tissue and to move relative to the elongate member and the flexible tube. The cauterizing member may substantially surround at least a portion of the elongate member. | 04-24-2014 |
Thi T. Nguyen, Saugus, MA US
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20090192220 | TREATMENT FOR SOLID TUMORS - A method for treating a solid tumor in a subject comprises administering to the subject an ACAT inhibitory compound or a prodrug thereof, for example avasimibe, wherein (a) the solid tumor is at least about 2 mm in diameter and (b) the compound or prodrug thereof is administered in an amount that is therapeutically effective, but ineffective to cause unacceptable toxicity to normoxic tissues. | 07-30-2009 |
Tien H. Nguyen, Westford, MA US
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20160053595 | Practical Alternative Microwave Technology to Enhance Recovery Heavy Oil in Reserviors - Extracting of Heavy Oil (Hydrocarbon) from Tar Sand and Oil Shale in deep reservoirs 7,000-12,000 feet below the ground surface by using Circular Waveguides Technology and Microwave Energy High Power System. Using Circular Waveguides as microwave energy radiator connects to the Microwave High Power System is the most practical method and provides a relatively cost-effective means of extract heavy oil from target Tar Sand or Oil Shale in deep reservoirs. This invention method can be applied for future new well bores that are in the plan to be drilled. It also can be used for existing un-use well bores that are being closed; waiting for cleaner new enhance oil recovery technology becoming available in order to reclaim of heavy oil without damaging the environment. | 02-25-2016 |
Toan B. Nguyen, Reading, MA US
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20100160314 | Small Molecule Inhibitors of Toll-Like Receptor 9 - Small molecule compounds and compositions containing said compounds useful for inhibiting signaling by certain Toll-like receptors (TLRs), particularly TLR9, are provided. The compounds and compositions can be used to inhibit immune responses, including unwanted immune responses in particular. Compounds, compositions, and methods are provided to treat a variety of conditions involving unwanted immune responses, including for example autoimmune disease, inflammation, transplant rejection, and sepsis. | 06-24-2010 |
Toan H. Nguyen, Billerica, MA US
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20150042206 | TRANSDUCER SYSTEMS - Transducer systems with reduced acoustic noise coupling are disclosed herein. In some embodiments, a transducer system includes pressure balancing features to prevent a floating portion of the transducer system from contacting a fixed portion of the transducer system, or to reduce the degree to which the floating portion is urged into contact with the fixed portion by process pressure or atmospheric pressure. In some embodiments, a transducer system includes one or more acoustic dampening elements, interruption grooves, annular projections, or dampening washers to reduce acoustic noise coupling between various components of the transducer system or between the transducer system and a flowcell in which the transducer system is mounted. | 02-12-2015 |
Toan Huu Nguyen, Needham, MA US
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20120304759 | SENSOR ASSEMBLY FOR USE WITH A FLUID TRANSPORT SYSTEM AND METHOD OF ASSEMBLING SAME - A sensor assembly for use with a fluid transport system is provided. The sensor assembly includes at least two sensors that are configured to measure a rate of flow of a fluid channeled through a pipeline of the fluid transport system. Moreover, the sensor assembly includes an annular collar that is coupled to the two sensors. The collar includes at least a first opening and at least a second opening defined therein. The first opening and the second opening are each sized to receive the two sensors therein such that the two sensors are substantially coaxially aligned with each other. A first sensor of the two sensors is positioned downstream from a second sensor of the two sensors. | 12-06-2012 |
20130174669 | METHOD AND APPARTUS FOR DETERMINING FLOW VELOCITY - A multimode flow meter can use both the time-of-transit of upstream and downstream ultrasonic signals and time for transmission of downstream-only signals to determine a flow velocity of a medium flowing through a conduit. Based on factors, such as previously computed flow velocity and signal-to-noise ratio of the upstream signal, a mode of operation may be switched and only the time for transmission of the downstream signals may be used to determine flow velocity. The multimode flow meter can computer cross-flow to reduce its effect on the determination of flow velocity. | 07-11-2013 |
20130219707 | SENSOR PORT INSERT APPARATUS - An insert apparatus for installing a transducer assembly in a sensor port of a flow cell is disclosed. The transducer assembly is installed in the cavity of the insert body without the use of glues or adhesives to bond the transducer assembly to the cavity. | 08-29-2013 |
20130283927 | ULTRASONIC FLOW MEASUREMENT SYSTEM - An ultrasonic flow measurement system having a first ultrasonic sensor with a first ultrasonic buffer and a second ultrasonic sensor with a second ultrasonic buffer is disclosed. The first and second ultrasonic buffers have different cross sections in order to reduce distortion of the ultrasonic signals. | 10-31-2013 |
20140083181 | REMOVABLE SENSOR PORT INSERT APPARATUS - An apparatus configured for insertion into a sensor port of a flow cell is disclosed. The apparatus includes an insert body, a sensor located in the cavity of the insert body, and an insert body holding nut and a sensor holding nut threaded to the interior surface of the sensor port. | 03-27-2014 |
20140084610 | APPARATUS FOR EXTRACTING AN OBJECT FROM A CAVITY - An apparatus for extracting an object from a cavity is disclosed. The apparatus includes a collet surrounded by a sleeve, which both extend into the cavity. Fingers of the collar of the collet are contracted to grasp the object by the advancement of the collet into the sleeve. The collet is advanced by rotating a nut, which is located outside of the cavity and engages with a threaded portion of the shaft of the collet. The shaft includes a groove extending through the threaded portion of the shaft. This groove engages with a protrusion extending from a handle to prevent the collet from rotating during rotation of the nut and advancement of the collet. The handle is located outside of the cavity and is held during the extraction. | 03-27-2014 |
Trung Hung Nguyen, Norton, MA US
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20140287273 | Portable Ground Power Source for Starting Aircraft - Methods and apparatus for a portable ground power source for starting aircraft. An apparatus includes a Li-ion battery pack and a NATO connector integrated into a single unit and packaged inside a light weight plastic housing. | 09-25-2014 |
Truong Q. Nguyen, Burlington, MA US
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20100166077 | APPARATUS AND METHOD FOR COMPRESSING VIDEO INFORMATION - A method and apparatus is disclosed for efficiently encoding data representing a video image, thereby reducing the amount of data that must be transferred to a decoder. The method includes transforming data sets utilizing a tensor product wavelet transform which is capable of transmitting remainders from one subband to another. Collections of subbands, in macro-block form, are weighted, detected, and ranked enabling prioritization of the transformed data. A motion compensation technique is performed on the subband data producing motion vectors and prediction errors which are positionally encoded into bit stream packets for transmittal to the decoder. Subband macro-blocks and subband blocks which are equal to zero are identified as such in the bit stream packets to further reduce the amount of data that must be transferred to the decoder. | 07-01-2010 |
Tu N. Nguyen, Billerica, MA US
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20130099179 | METAL NANOPARTICLE COMPOSITIONS FOR REFLECTIVE FEATURES - A composition for the fabrication of reflective features using a direct-write tool is disclosed. The composition comprises metal nanoparticles having an average particle size less than 300 nm and which carry thereon a polymer for substantially preventing agglomeration of the nanoparticles, wherein the nanoparticles exhibit a metal-polymer weight ratio of 100:1 to 10:1. The composition further includes a vehicle for forming a dispersion with the metal nanoparticles. A number of electronic devices comprising a reflective layer formed from the composition are also disclosed. One example case provides an electronic device having a reflective electrode. The reflective electrode comprises a percolation network of the metal nanoparticles embedded in a matrix of the polymer and having an average particle size of less than 300 nm, wherein the reflective electrode is reflective in the visible light range and does not diffract incident light. | 04-25-2013 |
Tuyen Nguyen, Randolph, MA US
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20140113957 | Compositions and Methods for Inhibition of Expression of Apolipoprotein C-III (APOC3) Genes - The invention relates to double-stranded ribonucleic acid (dsRNA) targeting an APOC3 gene, and methods of using the dsRNA to inhibit expression of APOC3. | 04-24-2014 |
Vinh Nguyen, Chelsea, MA US
Patent application number | Description | Published |
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20100291060 | SUBCUTANEOUS ADMINISTRATION OF ALPHA-GALACTOSIDASE A - The invention relates, in part, to improved methods of administering α-galactosidase A for the treatment of α-galactosidase A deficiencies including Fabry disease. | 11-18-2010 |
20140037612 | SUBCUTANEOUS ADMINISTRATION OF ALPHA-GALACTOSIDASE A - The invention relates, in part, to improved methods of administering α-galactosidase A for the treatment of α-galactosidase A deficiencies including Fabry disease. | 02-06-2014 |
20140219987 | STABILIZED COMPOSITIONS OF PROTEINS HAVING A FREE THIOL MOIETY - Compositions of proteins having free thiols, and methods of making and using such compositions, are described. | 08-07-2014 |
20150283216 | STABILIZED COMPOSITIONS OF PROTEINS HAVING A FREE THIOL MOIETY - Compositions of proteins having free thiols, and methods of making and using such compositions, are described. | 10-08-2015 |
20150306187 | SUBCUTANEOUS ADMINISTRATION OF ALPHA-GALACTOSIDASE A - The invention relates, in part, to improved methods of administering α-galactosidase A for the treatment of α-galactosidase A deficiencies including Fabry disease. | 10-29-2015 |
Vinh T. Nguyen, Chelsea, MA US
Patent application number | Description | Published |
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20110091414 | STABILIZED COMPOSITIONS OF PROTEINS HAVING A FREE THIOL MOIETY - Compositions of proteins having free thiols, and methods of making and using such compositions, are described. | 04-21-2011 |