Patent application number | Description | Published |
20080317141 | Method for Calculating Functions of the Channel Matrices in Linear Mimo-Ofdm Data Transmission - The present application describes a method for transmitting data through a MIMO-OFDM system which requires the computation of a function f(H(sk)), where H is the channel matrix and sk=exp(j*2*pi*k/N). The method splits function f into a first, nonpolynomial part, which is in turn a function of one or more polynomial functions in sk. | 12-25-2008 |
20090063106 | METHOD AND DEVICE FOR DECODING A SIGNAL OF MULTIPLE INPUT/MULTIPLE OUTPUT SYSTEM - The method for decoding a received signal in a multiple input/multiple output system uses QR-decomposition of the linear channel matrix, but then applies a non-Euclidean norm during tree traversal. Two separate hardware units, namely an MCU and a MEU, art provided for concurrent operation. The MCU determines a next child node, while the MEU determines next best parent nodes on the previously processed tree levels, which makes it possible to retrace the path to a next starting node without investing dedicated processing steps (e.g., cycles). On each tree level, the possible coordinates are grouped into several circular sets in the complex plane, and a series of decision boundaries is calculated for each set that allows a quick evaluation of the optimum coordinate in each set. | 03-05-2009 |
20090304114 | METHOD FOR DECODING DIGITAL INFORMATION ENCODED WITH A CHANNEL CODE - The performance of multiple-input multiple-output (MIMO) systems, employing coding with multiple antennas depends heavily on the demapper algorithm which is used for MIMO detection. Soft-output demappers lead to better bit error rate (BER) performance compared to hard-decision demappers, but have a higher implementation complexity. The algorithm, proposed in this paper, relies on low-complexity harddecision MIMO detection. The reliability information for the received bits used to compute log-likelihood ratios is based on an estimate of the average bit error rate which is for example derived from the corresponding channel state information only. The algorithm is applicable to any hard-decision MIMO detector. As an example, we describe the application of the scheme to a linear MMSE detector and to sphere decoding with early termination. | 12-10-2009 |
Patent application number | Description | Published |
20150274551 | STEAM GENERATION SYSTEM - The instant disclosure relates to steam generation systems. The disclosed steam generation systems, in some aspects, may relate to a forced circulation boiler that may be used in association with low energy water treatment systems. In certain aspects, the disclosed steam generation systems may allow for more environmentally-responsible steam generation. | 10-01-2015 |
20160076345 | PRODUCED WATER STEAM GENERATION PROCESS USING PRODUCED WATER BOILER WITH GAS TURBINE - A method and system for producing steam for use in heavy hydrocarbon recovery operations. Water, containing impurities, produced from the well is separated from hydrocarbons and other materials, and subsequently directly passed to a produced water boiler with online pigging. The boiler is indirectly heated by means of a hot flue gas, such as a gas turbine exhaust, which produces electricity (for powering a central processing facility, or alternatively a burner to heat the boiler) and exhaust heat for heating the boiler. | 03-17-2016 |
20160076346 | DISTRIBUTED STEAM GENERATION PROCESS FOR USE IN HYDROCARBON RECOVERY OPERATIONS - A method and system for producing steam for use in heavy hydrocarbon recovery operations. In an arrangement with or without a central processing facility and/or a plurality of well pads in communication with the central processing facility, each well pad is provided with equipment for separation of materials produced from its respective wells, and steam generation equipment for that well pad, thus allowing for simplified piping transport. | 03-17-2016 |
Patent application number | Description | Published |
20090101585 | Chromatographic methods - The current invention comprises a method for the regeneration of a cation exchange chromatography column. | 04-23-2009 |
20090118476 | Purification of pegylated polypeptides - The invention is a method for the purification of mono-PEGylated erythropoietin using two cation exchange chromatography steps wherein the same type of cation exchange material is used in both cation exchange chromatography steps and a method for producing a mono-PEGylated erythropoietin in substantially homogeneous form. | 05-07-2009 |
20110065903 | Chromatographic methods - The current invention comprises a method for the regeneration of a cation exchange chromatography column. | 03-17-2011 |
20110118448 | Purification of pegylated polypeptides - The invention is a method for the purification of mono-PEGylated erythropoietin using two cation exchange chromatography steps wherein the same type of cation exchange material is used in both cation exchange chromatography steps and a method for producing a mono-PEGylated erythropoietin in substantially homogeneous form. | 05-19-2011 |
20120177640 | OPTIMIZING THE PRODUCTION OF ANTIBODIES - A general method is provided for the production of purified antibodies by separation of an antibody molecule from an antibody variant by chromatographic methods, e.g. to enhance therapeutic efficacy, by for example choosing a specific harvesting time point and/or a specific purification scheme. The current invention thus reports a method for producing an antibody composition comprising an antibody molecule and a variant thereof, comprising the following steps: providing a sample comprising the antibody molecule and a variant thereof, determining the presence of the antibody molecule and/or a variant thereof and/or the ratio of the amount of the antibody molecule or variant thereof to the sum of the amounts of the antibody molecule and the variant thereof, in an aliquot of said sample, determining a subsequent harvesting time point and/or antibody purification scheme on basis of the data obtained before, thereby producing an antibody composition comprising the antibody molecule and a variant thereof. | 07-12-2012 |
20160102149 | OPTIMIZING THE PRODUCTION OF ANTIBODIES - A general method is provided for the production of purified antibodies by separation of an antibody molecule from an antibody variant by chromatographic methods, e.g. to enhance therapeutic efficacy, by for example choosing a specific harvesting time point and/or a specific purification scheme. The current invention thus reports a method for producing an antibody composition comprising an antibody molecule and a variant thereof, comprising the following steps: providing a sample comprising the antibody molecule and a variant thereof, determining the presence of the antibody molecule and/or a variant thereof and/or the ratio of the amount of the antibody molecule or variant thereof to the sum of the amounts of the antibody molecule and the variant thereof, in an aliquot of said sample, determining a subsequent harvesting time point and/or antibody purification scheme on basis of the data obtained before, thereby producing an antibody composition comprising the antibody molecule and a variant thereof. | 04-14-2016 |
Patent application number | Description | Published |
20120316435 | INJECTOR SYSTEM - The present disclosure relates to an injector containing a processor, a pump or a motor with advance for a piston, which is suitable for driving liquid out of a cartridge, a data storage device, a device for data transfer, wherein the processor is electronically connected to the data storage device, to a control unit for the pump or the motor, and to the device for data transfer; wherein the injector is suitable for being connected to a container or a cartridge for fluid transfer, which container or cartridge contains a multiplicity of doses of a parenteral solution; wherein a data storage device is fixedly connected to the container or the cartridge; wherein the device for data transfer is suitable for reading out information from the data storage device on the container or the cartridge; and wherein at least one specification in respect of the identity of the product stored in the container or in the cartridge is stored in the data storage device on the container or the cartridge. The disclosure furthermore relates to a container or a cartridge, which contains a multiplicity of doses of a parenteral solution, wherein a data storage device is fixedly connected to the container or the cartridge. | 12-13-2012 |
20120330152 | FLUID MANAGEMENT SYSTEM - The fluid management system according to the invention is adapted to automatically supply fluid for injection into a patient. The fluid management system comprises a fluid management device, a fluid transfer system and a fluid injector. The fluid management device serves to store and administrate multi dose containers. The fluid transfer system connects the outlet of the containers stored within the fluid management device to the injector and the injector withdraws the fluid via fluid transfer system from the containers and injects the fluid to an administration device at the patient. The fluid management device comprises at least one rotating carousel with the axis of rotation being vertically, at least two container holders attached to the rotating carousel, said container holders being adapted to position a container vertically with the open end of the neck facing downwards and a spike holder mounted below the rotating carousel and oriented such that the spike holder would axially align a spike connected to the spike holder with the axis of the container that is to be spiked and loaded into the container holder. | 12-27-2012 |
Patent application number | Description | Published |
20120218014 | Methods and Devices for Multiple-Mode Radio Frequency Synthesizers - Methods and devices provide for determining whether to operate a radio frequency synthesizer in a first mode of operation or a second mode of operation based on a reference frequency signal. The radio frequency synthesizer includes a digitally-controlled oscillator configured to generate an oscillator signal having an output frequency. A digital frequency locked-loop is configured to control the output frequency of the oscillator signal in a first mode of operation based on a first control signal. A digital phase locked-loop is configured to control the output frequency of the oscillator signal in a second mode of operation based on a second control signal. A controller determines whether to operate in the first mode or second mode based on a reference frequency signal. The controller generates the first or second control signal based on the determination of operating in the first or second mode, respectively. | 08-30-2012 |
20120328065 | Methods and Devices for Implementing All-Digital Phase Locked Loop - An all-digital phase locked loop includes a time to digital converter that determines a fractional portion of a phase count. The time to digital converter has a quantization error that may be caused by phase noise, delay errors or skew errors. Several methods and devices may reduce the quantization error. A noise source may add dithering to the reference clock at an input of the time to digital converter. A digital processor may use two successive rising edges of the oscillator signal to count time delays of the time to digital convertor to the reference clock, and uses these counts to determine a ratio of the time delays and the time period of the oscillator signal for controlling a digitally controlled oscillator. A radio frequency counter circuit detects whether the oscillator signal leads or lags the reference clock because of skew and generates a phase signal to correct the skew. | 12-27-2012 |
20140218086 | METHODS AND DEVICES FOR MULTIPLE-MODE RADIO FREQUENCY SYNTHESIZERS - Methods and devices provide for determining whether to operate a radio frequency synthesizer in a first mode of operation or a second mode of operation based on a reference frequency signal. The radio frequency synthesizer includes a digitally-controlled oscillator configured to generate an oscillator signal having an output frequency. A digital frequency locked-loop is configured to control the output frequency of the oscillator signal in a first mode of operation based on a first control signal. A digital phase locked-loop is configured to control the output frequency of the oscillator signal in a second mode of operation based on a second control signal. A controller determines whether to operate in the first mode or second mode based on a reference frequency signal. The controller generates the first or second control signal based on the determination of operating in the first or second mode, respectively. | 08-07-2014 |
20150249455 | METHODS AND DEVICES FOR IMPLEMENTING ALL-DIGITAL PHASE LOCKED LOOP - An all-digital phase locked loop includes a time to digital converter that determines a fractional portion of a phase count. The time to digital converter has a quantization error that may be caused by phase noise, delay errors or skew errors. Several methods and devices may reduce the quantization error. A noise source may add dithering to the reference clock at an input of the time to digital converter. A digital processor may use two successive rising edges of the oscillator signal to count time delays of the time to digital convertor to the reference clock. The digital processor uses these counts to determine a ratio of the time delays and the time period of the oscillator signal for controlling a digitally controlled oscillator. A radio frequency counter circuit detects whether the oscillator signal leads or lags the reference clock because of skew and generates a phase signal to correct the skew. | 09-03-2015 |
Patent application number | Description | Published |
20100288043 | Method and apparatus for extended time and varying environment measurements of single particles in microfluidic channels - Methods and apparatus for improving measurements of particle or cell characteristics, such as mass, in Suspended Microchannel Resonators (SMR's). Apparatus include in particular designs for trapping particles in SMR's for extended measurement periods and for changing the fluid properties within the SMR during the extended periods. Methods include techniques to provide for cell growth over time and over time in response to changing fluid properties to aid in determining parameters such as drug resistance and drug susceptibility. | 11-18-2010 |
20110124095 | Method and apparatus for high throughput diagnosis of diseased cells with microchannel devices - The method and apparatus of the present invention detects changes in cell biomechanics caused by any of a variety of diseases and conditions. In one embodiment, the method and apparatus of the invention detect infection of red blood cells. In one embodiment, the invention is a method and apparatus comprising a microfluidic channel with a constriction, for trapping infected red blood cells while allowing healthy red blood cells to deform and pass through the channel. In another embodiment, the invention comprises a suspended microchannel resonator for detecting and counting red blood cells at the constriction of the microfluidic channel. | 05-26-2011 |
20110271747 | Method and apparatus for integrated measurement of the mass and surface charge of discrete microparticles using a suspended mirochannel resonator - Measurements of the mass and surface charge of microparticles are employed in the characterization of many types of colloidal dispersions. The suspended microchannel resonator (SMR) is capable of measuring individual particle masses with femtogram resolution. The high sensitivity of the SMR resonance frequency to changes in particle position in the SMR channel is employed to determine the electrophoretic mobility of discrete particles in an applied electric field. When an oscillating electric field is applied to the suspended microchannel, the transient resonance frequency shift corresponding to a particle transit can be analyzed to extract both the buoyant mass and electrophoretic mobility of each particle. These parameters, together with the mean particle density, can be used to compute the size, absolute mass, and surface charge of discrete particles. | 11-10-2011 |
20120118063 | APPARATUS AND METHOD FOR MEASURING BUOYANT MASS AND DEFORMABILITY OF SINGLE CELLS - Method for determining buoyant mass and deformability of a cell. The method includes introducing the cell into a suspended microchannel resonator that includes a constriction near a distal location in the resonator. A first frequency shift in the resonator is monitored as a cell moves to the distal location in the resonator, the first frequency shift being related to the buoyant mass of the cell. Transit time of the cell through the constriction is measured by monitoring a second frequency shift as a result of a change in cell location as it passes through the constriction, whereby deformability is determined from the measured buoyant mass and transit time. | 05-17-2012 |
20140096604 | Method and Apparatus for Trapping Single Particles in Microfluidic Channels - Methods and apparatus for improving measurements of particle or cell characteristics, such as mass, in Suspended Microchannel Resonators (SMR's). Apparatus include in particular designs for trapping particles in SMR's for extended measurement periods. Methods include techniques to provide differential measurements by varying the fluid density for repeated measurements on the same particle or cell. | 04-10-2014 |