Sonia
Sonia Aït-Amar, Orsay FR
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20110060581 | METHOD FOR EVALUATING THE EXTENT OF THE PROTECTION AREA GRANTED BY A LIGHTNING CAPTURING DEVICE - A method for evaluating the extent (D) of the protection area granted by a lightning capturing device ( | 03-10-2011 |
Sonia Aït-Amar, Orsay FR
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20110060581 | METHOD FOR EVALUATING THE EXTENT OF THE PROTECTION AREA GRANTED BY A LIGHTNING CAPTURING DEVICE - A method for evaluating the extent (D) of the protection area granted by a lightning capturing device ( | 03-10-2011 |
Sonia Andersson, Stockholm SE
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20090035763 | Methods for Detecting Progression of Low Grade Cervical Dysplasia and for Detecting Adenocarcinomas - The invention provides methods for identifying conditions of low grade cervical dysplasia and assessing the progressive potential of individual lesions to develop into high grade cervical dysplasia and cervical squamous cell cancer as well as cervical adenocarcinoma. | 02-05-2009 |
20140005063 | METHOD FOR DETECTING RISK OF PROGRESSION OF LOW GRADE CERVICAL DYSPLASIA | 01-02-2014 |
Sonia Balzi, Coriano (rn) IT
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20140079835 | COMPOSITIONS CONTAINING RESVERATROL AND ESSENTIAL OIL OF CLOVES FOR THE TREATMENT OF ITCHING - The present invention relates to a patch or sticking plaster formulation containing a combination of resveratrol or derivatives thereof and essential oil of cloves ( | 03-20-2014 |
Sonia Biondaro, Ronca IT
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20110144068 | 3,4-DIARYLPYRAZOLES AS PROTEIN KINASE INHIBITORS - 3,4-diarylpyrazole derivatives of formula (I) as defined in the specification, and pharmaceutically acceptable salts thereof, process for their preparation and pharmaceutical compositions comprising them are disclosed; the compounds of the invention may be useful, in therapy, in the treatment of diseases associated with a disregulated protein kinase activity, like cancer. | 06-16-2011 |
Sonia Biondaro, Ronca (vr) IT
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20140005150 | 3,4-DIARYLPYRAZOLES AS PROTEIN KINASE INHIBITORS | 01-02-2014 |
Sonia Bisicchia, Abano Terme (pd) IT
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20140099673 | PROCESS FOR THE PRODUCTION OF HYALURONIC ACID IN ESCHERICHIA COLI OR BACILLUS MEGATERIUM - The present invention relates to a method of producing hyaluronic acid (HA) in | 04-10-2014 |
Sonia Budroni, Martis IT
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20120070457 | Polypeptides from neisseria meningitidis - Polypeptides comprising | 03-22-2012 |
Sonia Camaño Paez, Madrid ES
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20110165264 | USE OF CILASTATIN TO REDUCE NEPHROTATOXICITY OF VARIOUS COMPOUNDS - Use of cilastatin to reduce the nephrotoxicity of different compounds. The invention refers to use of cilastatin to prepare a medicinal product to reduce the nephrotoxicity of a nephrotoxic compound that enters the cells of the proximal tubule through cholesterol rafts. The invention is based on the discovery that a great number of nephrotoxic compounds, including drugs, enter the cells of the proximal tubule through the cholesterol rafts, and that cilastatin is able to interfere with this transport mechanism, decreasing the nephrotoxicity of such compounds to a variable extent. The nephroprotective effect is common to compounds of different chemical nature and solubility and is specific for the kidney, causing no interference with the effects of nephrotoxic drugs having their targets in other organs. Therefore, administration of cilastatin allows for decreasing the nephrotoxic effects of different drugs without reducing their therapeutic effects. | 07-07-2011 |
Sonia Campoy Garcia, Armilla - Granada ES
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20110189726 | BIOSYNTHESIS OF DERIVATIVES OF MONACOLIN J - The invention relates to a process for obtaining monacolin J derivatives (I), wherein R | 08-04-2011 |
20140309295 | ANTIEPILEPTIC, HYPOCHOLESTEROLEMIC AND NEUROPROTECTIVE COMPOUND - The present invention describes a compound of formula (I) | 10-16-2014 |
Sonia Campoy García, Armilla-Granada ES
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20120095091 | ANTIEPILEPTIC, HYPOCHOLESTEROLEMIC AND NEUROPROTECTIVE COMPOUND - The present invention describes a compound of formula (I) | 04-19-2012 |
Sonia Cantel, Nice FR
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20110003943 | Supported Oxidation Reactants, Process for their Preparation and Uses Thereof - The present invention relates to a supported oxidation reactant of formula (I): R-[Met(O) | 01-06-2011 |
Sonia Carallo, Aradeo (lecce) IT
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20090014070 | Electroactive device based on organic compounds, comprising a float-glass substrate - An electroactive photonic device (D) comprises a substrate ( | 01-15-2009 |
Sonia Castanon De La Torre, Derio (bizkaia) ES
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20130260407 | METHOD FOR THE PURIFICATION AND STABILISATION OF ENZYME GLUCONATE DEHYDROGENASE (GADH, EC 1.1.99.3), ENZYME GLUCONATE DEHYDROGENASE (GADH, EC 1.1.99.3), AND THE USE OF ENZYME GLUCONATE DEHYDROGENASE (GADH, EC 1.1.99.3) - Process of purification and stabilization of the enzyme Gluconate Dehydrogenase (GADH, EC 1.1.99.3) either recombinant or not, from several microorganisms such as: | 10-03-2013 |
Sonia Cellot, Montreal CA
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20090215875 | METHODS AND KITS FOR EXPANDING HEMATOPOIETIC STEM CELLS - A method of increasing the expansion and/or differentiation of a hematopoietic stem cell (HSC) comprising: (a) increasing the level and/or activity of a polypeptide encoded by at least one gene selected from trim27, xbp1, sox4, smarcc1, sfpi1, fos, hmgb1, hnrpdl, vps72, tcfec, klf10, zfp472, ap2a2, gpsm2, gpx3, erdr1, tmod1, cnbp1, prdm16, hdac1, pml and ski, or a functional variant of said polypeptide, in said cell; (b) increasing the level of a nucleic acid encoding the polypeptide or functional variant of (a) in said cell; or (c) any combination of (a) and (b). | 08-27-2009 |
Sonia Chalbot, New York, NY US
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20100273196 | System and Method for Evaluating Blood-Neural Barrier Permeability - A system and method for evaluating blood-neural barrier permeability. Phospholipid liposomes are labeled with a fluorescent phospholipase A | 10-28-2010 |
Sonia Deola, Falcade(bl) IT
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20090045962 | CABLE OR BAND WITH A SEQUENCE OF RADIOFREQUENCY IDENTIFICATION INTEGRATED CIRCUITS (RFID) HAVING INDEPENDENT ANTENNA CIRCUIT AND USE OF THE RADIOFREQUENCY IDENTIFICATION IN INTEGRATED CIRCUITS - The invention relates to a filament or tape comprising a plurality of radio frequency identification integrated circuits (RFID), each one provided with independent antenna circuits, placed in sequence on a support. | 02-19-2009 |
Sonia Divney, Boston, MA US
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20130337047 | COMPOSITIONS FOR TREATING ORAL AND PERIODONTAL INFECTIONS - The present invention provides novel compositions, and their methods of manufacture and use, comprising a formulation with a mucoadhesive polymer carrying a positive charge such as low molecular weight chitosan, a negatively charged lipid and H2 antagonist useful in the prevention and treatment of oral infectious disease in a nanotechnology or coated liposome carrier. | 12-19-2013 |
Sonia Dugardeyn, Braine Le Comte BE
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20110040284 | GUIDE FOR CATHETERISM - A guide is used for the selective catheterism of anatomic structures and for placing therapeutic instruments. | 02-17-2011 |
20110125108 | SURGICAL INSTRUMENT PREFERABLY WITH TEMPERATURE CONTROL - A surgical needle has shape memory. An endoscope tool controls the temperature of a foreign body or surgical instrument such as an endoscopic needle. | 05-26-2011 |
Sonia Escaich, Paris FR
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20090081224 | Compositions of polypeptides specific to pathogenic strains and their use as vaccines and in immunotheraphy - The invention relates to compositions of polypeptides specific to pathogenic strains comprising at least one polypeptide of a first group, having a sequence selected in the group comprising the sequences of SEQ ID No. 159, or homologous sequences of polypeptides of the first group and/or the second group with a minimum of 25% of identity with the whole sequences of said polypeptides. Application for the preparation of vaccine compositions specific to | 03-26-2009 |
20100022541 | Chemical inhibitors of bacterial heptose synthesis, methods for their preparation and biological applications of said inhibitors - The invention relates to new compounds having heptose synthesis inhibitory properties, of formula (I) or a pharmaceutically acceptable salt, or prodrug thereof, wherein A is an aryl or heterocycle, optionally substituted by one or several identical or different R such as H, C1-C10 alkyl, C1-C10 alkyl-OR | 01-28-2010 |
20100130489 | IMIDAZOLO-HETEROARYL DERIVATIVES WITH ANTIBACTERIAL PROPERTIES - The invention relates to Imidazolo-heteroaryl derivatives of formula (I). The compounds inhibit the activity of the Dlta enzyme of Gram-positive bacteria and are useful to treat Gram-positive bacterial infections. Furthermore the application discloses method for assessing the Dlta inhibitory activity of tested molecules and a method for measuring the efficacy of molecules in inhibiting bacteria proliferation in vitro. | 05-27-2010 |
20100260789 | PRODUCTS SPECIFIC TO PATHOGENIC STRAINS AND THEIR USE AS VACCINES AND IN IMMUNOTHERAPY - The invention relates to isolated antigenic polypeptides obtainable by a process comprising the steps of: 1—selecting on the basis of sequence analysis those of the polypeptides which are either located in the outermembrane or secreted by the bacteria, 2—identifying the genes coding for said polypeptides which are conserved in B2/D clinical isolates, 3—purifying the polypeptides identified in step 1, which are found in step 2 to be conserved in B2/D isolates, 4—testing the polypeptides for immunogenicity using animals models. Application for making vaccines compositions and immunotherapies. | 10-14-2010 |
20100261618 | Identification of genes implicated in the virulence of streptococcus agalactiae | 10-14-2010 |
20100316647 | COMPOSITIONS OF POLYPEPTIDES SPECIFIC TO PATHOGENIC STRAINS AND THEIR USE AS VACCINES AND IN IMMUNOTHERAPY - The invention relates to compositions of polypeptides specific to pathogenic strains comprising at least one polypeptide of a first group, having a sequence selected in the group comprising the sequences of SEQ ID No 159, or homologous sequences of polypeptides of the first group and/or the second group with a minimum of 25% of identity with the whole sequences of said polypeptides. Application for the preparation of vaccine compositions specific to | 12-16-2010 |
20110236886 | PATHOGENICITY DETERMINANTS WHICH CAN BE USED AS TARGETS FOR DEVELOPING MEANS FOR PREVENTING AND CONTROLLING BACTERIAL INFECTIONS AND/OR SYSTEMIC DISSEMINATION - The invention relates to a method for identifying and selecting a gene required for the proliferation in vivo of a pathogenic microorganism, comprising:—using a strain of the pathogenic microorganism,—generating mutants for inactivation in the genes encoding these factors,—determining the virulence of these mutants on an experimental model of infection, and their effect on enteric colonization in an axenic mouse model, and—selecting the bacterial genes essential for resistance to serum in vitro, and essential, in the host, for dissemination in the serum. Application to the screening of compounds which inhibit the products of the genes identified, and to the inhibition in vitro of the proliferation of a pathogenic microorganism in serum. | 09-29-2011 |
20120232079 | NOVEL ACYLPIPERAZINONES AND THEIR USE AS PHARMACEUTICALS - The invention relates to novel acylpiperazinone compounds, to the preparation of the compounds and intermediates used therein, to the use of the compounds as antibacterial medicaments and pharmaceutical compositions containing the compounds. | 09-13-2012 |
20120277207 | NOVEL HETEROCYCLIC ACRYLAMIDES AND THEIR USE AS PHARMACEUTICALS - The invention relates to novel heterocyclic acrylamide compounds (I), to the preparation of the compounds and intermediates used therein, to the use of the compounds as antibacterial medicaments and pharmaceutical compositions containing the compounds. | 11-01-2012 |
20130137689 | NOVEL ACYLPIPERAZINONES AND THEIR USE AS PHARMACEUTICALS - The invention relates to novel acylpiperazinone compounds, to the preparation of the compounds and intermediates used therein, to the use of the compounds as antibacterial medicaments and pharmaceutical compositions containing the compounds. | 05-30-2013 |
20140357617 | NOVEL HETEROCYCLIC ACRYLAMIDES AND THEIR USE AS PHARMACEUTICALS - The invention relates to novel heterocyclic acrylamide compounds (I), to the preparation of the compounds and intermediates used therein, to the use of the compounds as antibacterial medicaments and pharmaceutical compositions containing the compounds. | 12-04-2014 |
Sonia Escolastico, Valencia ES
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20130216938 | CO2 TOLERANT, MIXED CONDUCTIVE OXIDE AND USES THEREOF FOR HYDROGEN SEPARATION - The material according to the invention is based on a material having the composition Ln | 08-22-2013 |
Sonia Escolástico Rozalén, Valencia ES
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20110183221 | CATALYTIC LAYER FOR OXYGEN ACTIVATION ON IONIC SOLID ELECTROLYTES AT HIGH TEMPERATURE - The present invention relates to a catalytic porous layer for oxygen activation that can be used in solid oxide fuel cells (SOFC) and dense ceramic membranes for oxygen separation at a high temperature. This porous layer is mainly composed of an electron and oxygen ion mixed conductive material and has a structure selected from simple perovskite-type structures, double perovskite-type structures or perovskite-related structures, i.e. structures such as the Ruddlesden-Popper, Dion-Jacobson and Aurivillius type. The composition of this crystalline phase has the following general formula: | 07-28-2011 |
Sonia Garapaty, Frisco, TX US
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20120315869 | METHOD FOR OBTAINING LOCATION INFORMATION FOR EMERGENCY SERVICES IN WIRELESS MULTIMEDIA NETWORKS - A method and apparatus for obtaining end-user location information for emergency services within a multimedia network is presented. The multimedia network may include a network implementing the Session Initiation Protocol, H.323, etc. In one embodiment, a Location Application Server (LAS) in the multimedia network and an interface between the LAS and a gateway mobile location center (GMLC) is defined. | 12-13-2012 |
20130231078 | Method for Obtaining Location Information for Emergency Services in Wireless Multimedia Networks - A method and apparatus for obtaining end-user location information for emergency services within a multimedia network is presented. The multimedia network may include a network implementing the Session Initiation Protocol, H.323, etc. In one embodiment, a Location Application Server (LAS) in the multimedia network and an interface between the LAS and a gateway mobile location center (GMLC) is defined. | 09-05-2013 |
20140187194 | Method for Obtaining Location Information for Emergency Services in Wireless Multimedia Networks - A method and apparatus for obtaining end-user location information for emergency services within a multimedia network is presented. The multimedia network may include a network implementing the Session Initiation Protocol, H.323, etc. In one embodiment, a Location Application Server (LAS) in the multimedia network and an interface between the LAS and a gateway mobile location center (GMLC) is defined. | 07-03-2014 |
20150016346 | Method for Obtaining Location Information for Emergency Services in Wireless Multimedia Networks - A method and apparatus for obtaining end-user location information for emergency services within a multimedia network is presented. The multimedia network may include a network implementing the Session Initiation Protocol, H.323, etc. In one embodiment, a Location Application Server (LAS) in the multimedia network and an interface between the LAS and a gateway mobile location center (GMC) is defined. | 01-15-2015 |
Sonia Garcia Arrieta, San Sebastian (guipuzcoa) ES
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20110148000 | Process and Device for Polymerizing Lactams Molds - The invention relates to a process and device for polymerizing lactams in molds wherein the monomer, catalyst and initiator are independently fed to a mixing head feeding a mold. The system in turn comprises a series of feeding and recirculation conduits and reservoirs the temperature of which is regulated to perform the polymerization in a controlled manner. | 06-23-2011 |
Sonia Garcia-Blanco, Enschede NL
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20120228733 | MEMS-BASED GETTER MICRODEVICE - A MEMS (micro-electro-mechanical system) getter microdevice for controlling the ambient pressure inside the hermetic packages that enclose various types of MEMS, photonic, or optoelectronic devices. The getter microdevice revolves around a platform suspended at a height above a substrate, and which is supported by supporting legs having low thermal conductance. Layers are deposited on the platform, such layers including a properly patterned resistor element, a heat-spreading layer and, finally, a thin-film getter material. When an electrical current flows through it, the resistor element heats the thin-film getter material until it reaches its activation temperature. The getter material then absorbs the gas species that could be present in the hermetic package, such gas species possibly impairing the operation of the devices housed in the packages while reducing their lifetime. The weak thermal conductance between the platform and the substrate helps in preventing damages to the surrounding devices when the MEMS getter microdevice is heated at its activation temperature, and it reduces the electrical power required for reaching the activation temperature as well. | 09-13-2012 |
Sonia Garcia-Marco, Madrid ES
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20100022394 | PRODUCTS FOR THE TREATMENT OF THE IRON CHLOROSIS - The present invention consists on the synthesis of new products for the treatment of the iron chlorosis. These products may have improved properties regarding the currently known treatments. The new products are non-symmetrical ethylene diamino hidroxyphenyl acetic acid derivatives possessing only five coordination sites able to chelate metals. | 01-28-2010 |
Sonia Gazzetto, Cascinette D'Ivrea IT
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20120296113 | Process For The Preparation Of Thyroid Hormones And Salts Thereof - The present invention generally refers to a process for the preparation of L-thyroxine derivatives. More in particular, the present invention relates to a iodination reaction of an aromatic derivative with an appropriate iodinating agent, so to afford the related iodinated compound as disodium salt, which may represent a useful intermediate for the synthesis of the L-thyroxine mono-sodium salt, and the free form thereof. | 11-22-2012 |
20140024717 | Process For The Preparation Of A Sulfated Derivative Of 3,5-Diiodo-O-[3-Iodophenyl]-L-Tyrosine - The present invention relates to a process for the preparation of the mono sodium salt of the derivative 3,5-diiodo-O-[3-iodo-4-(sulphooxy)phenyl]-L-tyrosine (T3S) by starting from the corresponding phenolic compound, in the presence of chloro-sulfonic acid and dimethylacetamide as a solvent. The so obtained T3S compound may conveniently be isolated in a pure form as a solid in good yields. The present invention further relates to the process for T3S preparation, wherein the starting reagent is T2 and further comprising the formulation of such compound in tablets. Furthermore, the invention discloses non-radioactive immunoassays based on T3S derivatives. | 01-23-2014 |
20140221477 | Process For The Preparation Of A Sulfated Derivative Of 3,5-Diiodo-O-[3-Iodophenyl]-L-Tyrosine - The present invention relates to a process for the preparation of the mono sodium salt of the derivative 3,5-diiodo-O-[3-iodo-4-(sulphooxy)phenyl]-L-tyrosine (T3S) by starting from the corresponding phenolic compound, in the presence of chlorosulfonic acid and dimethylacetamide as a solvent. The so obtained T3S compound may conveniently be isolated in a pure form as a solid in good yields. The present invention further relates to the process for T3S preparation, wherein the starting reagent is T2 and further comprising the formulation of such compound in tablets. Furthermore, the invention discloses non-radioactive immunoassays based on T3S derivatives. | 08-07-2014 |
Sonia Gonzalez Blanco, La Habana CU
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20120308615 | FORMULATION OF HEPATITIS B VIRUS ANTIGENS FOR CELLULAR STIMULATION FOLLOWED BY THERAPEUTIC IMMUNIZATION - The present invention is related with the field of the therapeutic immunization, specifically with the employment of a new formulation of antigens of the Hepatitis B Virus (HBV) for the cellular stimulation. The formulation is formed by the surface antigens (HBsAg) precipitated in suspension and the nucleocapsid (HBcAg) of the HBV. The formulation contains these antigens like suspended particles of sizes less than 500 nm and higher than 500 nm, in a mixture where the proportion among the particles of the mentioned sizes is among 50%-50% and 80%-20%, respectively. The selection of a range of sizes of particles allows that the levels of stimulation of several cellular types are maximized. Additionally, a cellular stimulation method is described with this formulation, and the later passive immunization of patients with chronic Hepatitis B, based on the maximum stimulation in vivo or in vitro using heterologous or autologous cells (dendritic cells, B cells and macrophages). The cells stimulated with this formulation are transferred to patients chronically infected with the HBV. | 12-06-2012 |
20140112976 | Cyclic Peptides with an Anti-Neoplasic and Anti-Angiogenic Activity - The present invention comprises cyclic peptides bearing antitumor and antiangiogenic properties, as well as their corresponding pharmaceutically-suitable salts and also pharmaceutical compositions containing it. These cyclic peptides are used to prepare medicines for human and/or veterinary therapeutics, and additionally in diagnosis. These compounds can be used to detect, monitor and/or control a range of cellular proliferation-related disorders, such as oncological diseases and undesired angiogenesis. Moreover, they can be included as part of controlled release systems, and used more precisely in the field of nanobiotechnology, either because of their self-assembly capacity or as part of other systems. | 04-24-2014 |
Sonia González Blanco, Ciudad De La Habana CU
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20100300166 | BIOFERTILIZER COMPOSITION - A composition to stimulate the development and growth of plants that comprises at least a | 12-02-2010 |
Sonia González Blanco, Ciudad De La Habana CU
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20090208521 | PHARMACEUTICAL COMPOSITIONS CONTAINING PROTEIN NMA0939 - The present invention is related to field of medicine, particularly to the development of pharmaceutical formulations containing NMA0939 protein. Formulations described in this invention are able to confer protection against different diseases caused or not by pathogenic agents. NMA0939 protein was identified as a | 08-20-2009 |
20090297547 | PHARMACEUTICAL COMPOSITION CONTAINING THE NMB0938 PROTEIN - The present invention is related to field of medicine, particularly to the development of pharmaceutical formulation containing NMB0938 protein. Formulation described in this invention is able to confer protection against different diseases caused or not by pathogenic agents. NMB0938 protein was identified as a | 12-03-2009 |
20100129387 | PHARMACEUTICAL COMPOSITION CONTAINING THE NMB0606 PROTEIN - The present invention is related to field of medicine, particularly to the development of pharmaceutical formulation containing NMB0606 protein. Formulation described in this invention is able to confer protection against different diseases caused or not by pathogenic agents. NMB0606 protein was identified as a | 05-27-2010 |
20100136062 | USE OF EPIDERMAL GROWTH FACTOR FOR THE MORPHOFUNCTIONAL RESTORATION OF PERIPHERAL NERVES IN DIABETIC NEUROPATHY - The invention relates to human medicine and to the use of epidermal growth factor (EGF) for preparing a pharmaceutical composition which is administered by infiltration into the periphery of nerve ganglia and/or trunks for the morphofunctional restoration of peripheral nerves in painful sensory-motor neuropathy as well as manifestations of ischemic neuritis. The invention also includes a composition containing EGF which can be formulated together with anaesthetics or analgesics or encapsulated in microspheres and to the use thereof for the morphofunctional restoration of peripheral nerves in painful sensitive-motor-type diabetic neuropathy and the manifestations of ischemic neuritis. | 06-03-2010 |
20100172931 | Pharmaceutical Composition Containing the NMB1796 Protein - The present invention is related to field of medicine, particularly to the development of pharmaceutical composition containing the NMB1796 protein. The composition described in this invention are able to confer protection against different diseases caused or not by pathogenic agents. The NMB1796 protein was identified as a | 07-08-2010 |
20100300166 | BIOFERTILIZER COMPOSITION - A composition to stimulate the development and growth of plants that comprises at least a | 12-02-2010 |
20140105990 | USE OF EPIDERMAL GROWTH FACTOR FOR THE MORPHOFUNCTIONAL RESTORATION OF PERIPHERAL NERVES IN DIABETIC NEUROPATHY - The present invention is relevant to human medicine, and, in particular, to the use of Epidermal Growth Factor (EGF) in a pharmaceutical composition, said composition is administered through infiltration at the periphery of nerve trunks and/or ganglia, for the morphofunctional restoration of peripheral nerves in painful, sensitive-motor neuropathy, as well as ischemic neuritis. It is also relevant to an EGF containing composition, where this molecule can be formulated together with anesthetic or analgesic drugs, or encapsulated in microspheres, and their use for the morphofunctional restoration of peripheral nerves in painful, sensitive-motor neuropathy, as well as in ischemic neuritis. | 04-17-2014 |
Sonia Gupta, Ann Arbor, MI US
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20080262680 | Apparatus and method for detecting vehicle rollover using an enhanced algorithm having lane departure sensor inputs - A method is provided including the steps of monitoring a lane departure event, monitoring a rollover event, and controlling actuation of an occupant restraining device in response to the monitored lane departure event and the monitored rollover even. | 10-23-2008 |
Sonia Hellen, Plano, TX US
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20110134628 | Continuous Fragrance and Illumination Device with Replaceable Fragrance Refills - One embodiment of a continuous fragrance and illumination device having replaceable fragrance refill trays each comprising a curved back member that drop into vented fragrance refill chambers arranged around an air-moving member and surrounded by an illumination chamber formed by the external surfaces of a lens, an air-moving member housing, and the interior surface of a translucent shell that is closely adjacent to those surfaces and supported by a protective bottom cap, or separated by a greater distance. In addition, a translucent vanishing-edge lid is supported that provides a non-visible vent for exiting air following an air flow direction upward through the device. Other embodiments are described and shown. | 06-09-2011 |
Sonia Hillios, Southampton, MA US
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20090259179 | INJECTION AID AND STABILITY DISK FOR SYRINGE OR INSULIN PEN - An injection aid for a syringe includes a disk with a central orifice and a flange. The flange is located on the top of the disk, and surrounds the central orifice. The outlet end or needle hub of a syringe or insulin pen fits in the flange, with the syringe needle extending through the orifice, thereby securing the disk to the syringe. The bottom surface of the disk is generally flat. The bottom surface of the disk makes contact with the skin when the needle is inserted to the proper depth. In other words, the needle lies perpendicular to the disk and is arranged to project past the disk's flat bottom surface by a set, pre-determined length. When the disk is pressed flat against a patient's skin, the needle is at the proper depth for the substance being injected. | 10-15-2009 |
Sonia Jahid, Champaign, IL US
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20130226663 | SYSTEMS AND METHODS FOR PROVIDING INTER-MARKET COLLABORATIVE SERVICES USING SOCIAL NETWORKS - Methods and systems for propagating requests for proposal via a collaborative services framework are provided. The methods include receiving a request for proposal from a first user in a first market that implements at least one peer node in the collaborative services framework and maintains lists of market neighbors and potential neighbors. The methods further include propagating the request for proposal to potential neighboring markets that are selected from a list of potential neighbors of the first market. The methods also include receiving a notification that the first user has accepted a bid from a second user responsive to the request for proposal, the second user being in a second market different from the first market, and then updating the lists of market neighbors and potential neighbors of the first market based on the accepted bid. | 08-29-2013 |
Sonia Jemli, Sfax TN
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20100173366 | Polypeptides Having L-Arabinose Isomerase Activity Exhibiting Minimum Dependence on Metal Ions for Its Activity and for Thermostability and Nucleic Acids Encoding the Same - The invention concerns identification of a gene encoding a novel L-arabinose isomerase of the | 07-08-2010 |
Sonia Kerrad, Huningue FR
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20090131419 | Sulphones which modulate the action of gamma secretase - Disclosed are sulphones which modulate the action of gamma-secretase. The compounds are useful in the treatment or prevention of Alzheimer's disease. | 05-21-2009 |
Sonia Krivonos, Beer Sheva IL
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20080234286 | STABLE AMORPHOUS IMATINIB MESYLATE AND PRODUCTION PROCESS THEREFOR - Provided herein is a spray dried stable amorphous imatinib mesylate as a free-flowing solid and process for producing the amorphous imatinib mesylate in highly pure form. | 09-25-2008 |
20080275055 | IMATINIB PRODUCTION PROCESS - Provided is a process for producing imatinib and salts thereof, e.g., imatinib mesylate. The process includes reacting4-(4-methyl-piperazin-1-ylmethyl)-benzoic acid with N-(5-amino-2-methylphenyl)-4-(3-pyridyl)-2-pyrimidine-amine in the presence of a carboxylic acid coupling reagent, to produce imatinib, and optionally converting the imatinib into a salt. | 11-06-2008 |
20090069306 | PROCESS FOR PRODUCING HIGHLY PURE MIDAZOLAM AND SALTS THEREOF - Provided is a process for producing highly pure midazolam and salts thereof, and a pharmaceutical composition containing the highly pure midazolam and/or a salt thereof. | 03-12-2009 |
20100222602 | CRYSTALLINE ROTIGOTINE BASE AND PREPARATION PROCESS THEREFOR - An isolated and pure crystalline rotigotine base of polymorph Form I, and processes for producing the crystalline rotigotine base are disclosed. Also disclosed is a transdermal patch for the delivery of rotigotine base using the disclosed isolated and pure form of rotigotine base, which can be used in treatment of Parkinson's Disease and other disorders ameliorated or treated by rotigotine, including restless leg syndrome. | 09-02-2010 |
20130096321 | CRYSTALLINE ROTIGOTINE BASE AND PREPARATION PROCESS THEREFOR - An isolated and pure crystalline rotigotine base of polymorph Form I, and processes for producing the crystalline rotigotine base are disclosed. Also disclosed is a transdermal patch for the delivery of rotigotine base using the disclosed isolated and pure form of rotigotine base, which can be used in treatment of Parkinson's Disease and other disorders ameliorated or treated by rotigotine, including restless leg syndrome. | 04-18-2013 |
Sonia Larbl Djaziri, Tunis TN
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20120213380 | Method and Device for Cancelling Acoustic Echo by Audio Watermarking - A method of cancelling acoustic echo in a first signal comprising an echo signal of a second signal, comprising: inserting, in an inaudible manner, into the second signal a pseudo-random sequence whose circular autocorrelation comprises a unit impulse and a continuous component; characterizing, in the first signal, by means of the inserted sequence, an acoustic channel followed by the echo signal; estimating the echo signal in the first signal by means of the characterization of the acoustic channel; and cancelling the echo signal by means of the obtained estimation. | 08-23-2012 |
Sonia Letant, Livermore, CA US
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20100065822 | LIPID NANOTUBE OR NANOWIRE SENSOR - A sensor apparatus comprising a nanotube or nanowire, a lipid bilayer around the nanotube or nanowire, and a sensing element connected to the lipid bilayer. Also a biosensor apparatus comprising a gate electrode; a source electrode; a drain electrode; a nanotube or nanowire operatively connected to the gate electrode, the source electrode, and the drain electrode; a lipid bilayer around the nanotube or nanowire, and a sensing element connected to the lipid bilayer. | 03-18-2010 |
Sonia López-Esteban, Oviedo ES
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20140065306 | NANOSTRUCTURED CALCIUM-SILVER PHOSPHATE COMPOSITE POWDERS, PROCESS FOR OBTAINING THE POWDERS AND BACTERICIDAL AND FUNGICIDAL APPLICATIONS THEREOF - Described in example embodiments are nanocomposite powders including calcium phosphate and silver nanoparticles on the surface of the calcium phosphate. Other example embodiments, describe methods of forming nanocomposite powders comprising a) preparing a nanometric calcium phosphate by a sol-gel processing route; and b) depositing silver nanoparticles on the calcium phosphate surface. Compositions including nanocomposite powders and uses of those compositions are also described. | 03-06-2014 |
Sonia López-Esteban, Oviedo ES
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20120040005 | NANOSTRUCTURED CALCIUM-SILVER PHOSPHATE COMPOSITE POWDERS, PROCESS FOR OBTAINING THE POWDERS, AND BACTERICIDAL AND FUNGICIDAL APPLICATIONS THEREOF - Described in example embodiments are nanocomposite powders including calcium phosphate and silver nanoparticles on the surface of the calcium phosphate. Other example embodiments, describe methods of forming nanocomposite powders comprising a) preparing a nanometric calcium phosphate by a sol-gel processing route; and b) depositing silver nanoparticles on the calcium phosphate surface. Compositions including nanocomposite powders and uses of those compositions are also described. | 02-16-2012 |
Sonia Lopez Giral, Madrid ES
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20090123483 | ANTI-CCR7 RECEPTOR ANTIBODIES FOR THE TREATMENT OF CANCER - Antibodies, or antigen-binding fragment thereof, which bind to a CCR7 receptor are capable of selectively killing, impairing migration and/or blocking dissemination of tumour cells expressing a CCR7 receptor. Use of said antibodies for killing or for inducing apoptosis of said tumour is disclosed, thus providing an alternative therapy for treatment of cancer which tumour cells express a CCR7 receptor. | 05-14-2009 |
Sonia Magaña, Tampa, FL US
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20110059462 | AUTOMATED PARTICULATE CONCENTRATION SYSTEM - An automated system for concentrating potentially harmful substances from various water types or other non-viscous liquids to facilitate detection of those substances is disclosed herein. The automated system comprises a water pressure driven or pump driven concentration unit that filters the test fluid through a hollow-fiber filter. Material collected on the filter is backflushed into a collection vessel by passing a small volume of sterile solution through the filter in the reverse direction. The automated system can be configured to be portable or to be integrated into a continuous liquid stream for online monitoring of test fluids. Optionally, an electronic signal at the end of the backflush sequence triggers a detector, such as an automated array biosensor, to begin processing and analyzing the sample. | 03-10-2011 |
Sonia Magaña, Tampa, FL US
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20110059462 | AUTOMATED PARTICULATE CONCENTRATION SYSTEM - An automated system for concentrating potentially harmful substances from various water types or other non-viscous liquids to facilitate detection of those substances is disclosed herein. The automated system comprises a water pressure driven or pump driven concentration unit that filters the test fluid through a hollow-fiber filter. Material collected on the filter is backflushed into a collection vessel by passing a small volume of sterile solution through the filter in the reverse direction. The automated system can be configured to be portable or to be integrated into a continuous liquid stream for online monitoring of test fluids. Optionally, an electronic signal at the end of the backflush sequence triggers a detector, such as an automated array biosensor, to begin processing and analyzing the sample. | 03-10-2011 |
Sonia Marsano, Arenzano IT
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20120166300 | MANAGEMENT OF SOFTWARE LICENSES IN A COMPUTER NETWORK - Management of software licenses in a client-server mode starts with a license policing based on clustering, nominally, into differently valued bundles many variegated applications to be licensed. Applications have an initial size which can be upgraded on request. The size may encompass a variable number of different entities. Two management processes run concurrently at the server side: a first one is dedicated to distribute licenses for new software applications and licenses for upgrading to new versions of previously licensed applications, and further checking any attempt to violate a software license; a second one, upon reception of specific requests by licensees, calculates the number of credits which are needed for upgrading the size previously licensed for applications, checks that available credits at the requesters be sufficient for upgrading, otherwise sends back a warning for insufficient credits. | 06-28-2012 |
Sonia Martínez Gonzalez, Madrid ES
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20120083492 | IMIDAZOPYRAZINES FOR USE AS KINASE INHIBITORS - There is provided compounds of formula (I), wherein R | 04-05-2012 |
20130131057 | NEW BICYCLIC COMPOUNDS AS PI3-K AND MTOR INHIBITORS - There is provided compounds of formula (I), wherein A | 05-23-2013 |
Sonia Maza Del Rio, Derio (bizkaia) ES
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20130260407 | METHOD FOR THE PURIFICATION AND STABILISATION OF ENZYME GLUCONATE DEHYDROGENASE (GADH, EC 1.1.99.3), ENZYME GLUCONATE DEHYDROGENASE (GADH, EC 1.1.99.3), AND THE USE OF ENZYME GLUCONATE DEHYDROGENASE (GADH, EC 1.1.99.3) - Process of purification and stabilization of the enzyme Gluconate Dehydrogenase (GADH, EC 1.1.99.3) either recombinant or not, from several microorganisms such as: | 10-03-2013 |
Sonia Merino Guijarro, Albacete ES
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20130210887 | DENDRIMERS AS NON-VIRAL VEHICLES FOR GENE THERAPY - The present invention relates to novel compounds of general formula (I) and (II) for their use in gene therapy as non-viral vehicles and their use for the preparation of a medicament. It also discloses the process of synthesis of said compounds of general formula (I) and (II). | 08-15-2013 |
Sonia Néron, Quebec CA
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20110313139 | METHOD FOR POLYCLONAL IMMUNOGLOBULIN G PRODUCTION BY HUMAN B CELLS - This application relates to an in vitro method of producing a polyclonal IgG preparation. The method comprises (i) placing a polyclonal B-cell population enriched in IgG-secreting B cells in a culture medium; and (ii) culturing the polyclonal B-cell population under conditions enabling the production of the polyclonal IgG preparation from the polyclonal B-cell population. This improved method enables the production of antibodies (preferably IgG) and facilitates long-term culture of polyclonal B-cell populations. | 12-22-2011 |
Sonia Nielles-Vallespin, Nurnberg DE
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20080205735 | METHOD FOR GENERATION OF TEMPORALLY HIGH-RESOLUTION MR EXPOSURES - In a method for generation of MR exposures in an MR system, a number of under-sampled MR raw data sets are acquired with non-constant density in k-space. A density compensation is implemented dependent on the geometry of the structure to be depicted. The under-sampled MR raw data sets are translated into a Cartesian coordinate system. Fourier transformation of the translated raw data sets in classical three-dimensional space ensues to generate under-sampled MR images. An averaged MR image is generated on the basis of a number of the under-sampled MR raw data sets. The MR exposures are produced by multiplication of the under-sampled MR images with the averaged MR image. | 08-28-2008 |
20080231275 | MAGNETIC RESONANCE METHOD AND APPARATUS FOR AUTOMATICALLY DETERMINING OBJECTS THAT ATTENUATE PENETRATING RADIATION - In a method and an apparatus for automatic determination of objects that attenuate high energy/penetrating radiation by magnetic resonance, the magnetic resonance apparatus scans and prepares MR images, and the MR images contain information about the T2 relaxation time constant. Subsequently, penetrating radiation-attenuating objects are determined in the MR images by means of the T2 relaxation time constant. | 09-25-2008 |
Sonia Ovarlez, Chatillon FR
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20110011310 | METHOD OF MANUFACTURING A COMPOSITE BASED ON COMPLEXES OF CONTROLLED STABILITY - The method for manufacturing a composite based on complexes of controlled stability over time using a fibrous inorganic matrix having tunnels and one or more organic compounds incorporated into said tunnels includes the following steps: the fibrous inorganic matrix having tunnels and the organic compound or compounds are provided; the fibrous inorganic matrix having tunnels is mixed with the organic compound or compounds so that said organic compound or compounds are incorporated into the tunnels of the fibrous inorganic matrix; the retention of the organic compound or compounds in said tunnels and their release therefrom by heating said mixture obtained, at a chosen temperature for a defined time, are controlled. The invention applies in particular in a preparation intended for cosmetic, pharmacological, nutri-therapeutic and agri-foodstuff, phytosanitary, petroleum or electronic usage or else in paints. | 01-20-2011 |
Sonia Paz Gómez, Santiago De Compostela ES
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20110313032 | COMPETITIVE INHIBITORS OF TYPE II DEHYDROQUINASE ENZYME - The present invention is directed to a compound of formula (I), its diastereoisomers, its enantiomers or its pharmaceutically acceptable salts or solvates, formula (I), to procedures of obtaining the same, to intermediates thereof, and use as competitive inhibitors of the third enzyme of the shikimic acid pathway, the type II dehydroquinase. | 12-22-2011 |
Sonia Pina Pedrero, Amer ES
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20100285070 | POLYNUCLEOTIDES OF HAEMOPHILUS PARASUIS AND ITS USE - The present invention relates to | 11-11-2010 |
Sonia Quattrociocchi, Richmond Hill CA
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20110097635 | SYSTEM AND METHOD FOR ELECTROCHEMICAL CELL SYSTEM AND LEAK DETECTION AND INDICATION - An electrochemical cell system is provided having: at least one electrochemical cell stack, each stack having at least one reactant fluid inlet; a pressure transmitter arranged in the at least one reactant fluid inlet of each stack; and a control unit for regulating the electrochemical cell system, the control unit receiving at least one signal value from the pressure transmitter indicative of the reactant fluid pressure. The control unit may compare the at least one signal value with a stored values and generate a leak indication based on the rate of pressure decay within the electrochemical cell system. A method of detecting and indicating a leak is also disclosed. | 04-28-2011 |
Sonia Rubico-Jamir, Andover, MA US
Sonia Scarfi, Genova IT
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20080242705 | Fluridone as an Anti-Inflammatory Agent - The invention relates to a novel use of fluridone—compound known per se and used as an aquatic erbicide—in the medical field, in particular as an active compound for preparing a medicament having anti-inflammatory activity. Pharmaceutical compositions comprising fluridone as an active compound and pharmaceutically acceptable carriers and/or diluents are also disclosed. Finally, there is disclosed the pro-inflammatory activity of abscisic acid (ABA), a plant hormone which is also found in mammal serum and against which fluridone acts an inhibitor. | 10-02-2008 |
Sonia Schnieper-Samec, Geneve CH
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20110257098 | COMPOSITIONS AND METHODS FOR TREATING GROWTH HORMONE DEFICIENCY - The present invention relates to the use of genetic markers to identify the response to growth hormone treatment in Growth Hormone Deficiency (GHD) or Turner Syndrome (TS) patients as well as a method of treating GHD or TS patients and kits for genotyping. | 10-20-2011 |
Sonia Schnieper-Samec, Geneva CH
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20130157952 | GENOMIC MARKERS FOR PREDICTION OF LONG-TERM RESPONSE TO GROWTH HORMONE (GH) THERAPY - The present invention relates to the use of genetic markers to identify the response to growth hormone treatment in Growth Hormone Deficiency (GHD) or Turner Syndrome (TS) patients as well as a method of treating GHD or TS patients and kits for genotyping. | 06-20-2013 |
Sonia Schoonbroodt, Lixhe BE
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20090311183 | METALLOPROTEINASE 12 BINDING PROTEINS - Proteins that bind to matrix metalloproteinase 12 and methods of using such proteins are described. | 12-17-2009 |
Sonia Serna Pereda, Bilbao ES
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20090163555 | SYNTHESIS AND USES OF PYROGLUTAMIC ACID DERIVATIVES - Novel pyroglutamic acid derivatives (I), wherein R | 06-25-2009 |
Sonia Sfasciotti, Acireale (catania) IT
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20110026613 | COMMUNICATION SYSTEM FOR A CONTROL CHANNEL, AND CORRESPONDING METHOD AND COMPUTER PROGRAM PRODUCT - A communication system for an HDMI communication interface CEC channel includes a communication module for receiving messages via the CEC channel, a processing unit for processing the received messages and an oscillator for driving the communication module. When the interface is in an active mode, the system is operative to activate the timer upon detection of the start of transmission of a first message, detect the initial bit of the first message, reconstruct and process the first message, and switch the interface from the active mode to standby by deactivating the oscillator. When the interface is in standby, the system is operative to switch the interface to the active condition by activating the oscillator and the timer when the start of a transmission of a second message is detected, detect the initial bit of a transmission of the second message, and reconstruct and process the second message. | 02-03-2011 |
Sonia Slimani, Maisons Alfort FR
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20090134132 | Laser Beam Welding Method with a Metal Vapour Capillary Formation Control - The invention relates to a method for welding at least one, preferably two metal parts to each other, by a laser beam consisting in using a laser beam ( | 05-28-2009 |
Sonia Taktak, Cambridge, MA US
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20110070657 | DETECTING IONS AND MEASURING ION CONCENTRATIONS - The present inventions include methods and compositions for detecting the presence of ions and measuring the level or concentration of ions in a sample by nuclear magnetic resonance (NMR) using magnetic particles. In particular, the inventions include the preparation and use of magnetic particles having synthetic ion chelators covalently bound to their surfaces. In the presence of target ions, the surface-modified magnetic particles form clusters, which can be monitored by NMR relaxation measurements. The relaxation times can then be used to detect specific ions and determine their concentration. The described methods, compositions, and devices are useful for a variety of applications including biomedical applications in diagnostics and imaging. | 03-24-2011 |
20110312002 | NMR DETECTION OF COAGULATION TIME - The invention relates to detecting coagulation and coagulation-related activities including agglutination and fibrinolysis of samples. More particularly the invention relates to methods and apparatus for monitoring coagulation and/or obtaining a coagulation time of a sample using NMR-based detectors. | 12-22-2011 |
Sonia Trépanier, St. Nicolas CA
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20100239610 | INFLUENZA VIRUS-LIKE PARTICLES (VLPS) COMPRISING HEMAGGLUTININ PRODUCED WITHIN A PLANT - A method for synthesizing influenza virus-like particles (VLPs) within a plant or a portion of a plant is provided. The method involves expression of influenza HA in plants and the purification by size exclusion chromatography. The invention is also directed towards a VLP comprising influenza HA protein and plants lipids. The invention is also directed to a nucleic acid encoding influenza HA as well as vectors. The VLPs may be used to formulate influenza vaccines, or may be used to enrich existing vaccines. | 09-23-2010 |
Sonia Trépanier, Saint-Nicolas CA
Patent application number | Description | Published |
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20100310604 | RECOMBINANT INFLUENZA VIRUS-LIKE PARTICLES (VLPS) PRODUCED IN TRANSGENIC PLANTS EXPRESSING HEMAGGLUTININ - A method for synthesizing influenza virus-like particles (VLPs) within a plant or a portion of a plant is provided. The method involves expression of influenza HA in plants and the purification by size exclusion chromatography. The invention is also directed towards a VLP comprising influenza HA protein and plants lipids. The invention is also directed to a nucleic acid encoding influenza HA as well as vectors. The VLPs may be used to formulate influenza vaccines, or may be used to enrich existing vaccines. | 12-09-2010 |
Sonia Trépanier, St. Nicolas CA
Patent application number | Description | Published |
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20100239610 | INFLUENZA VIRUS-LIKE PARTICLES (VLPS) COMPRISING HEMAGGLUTININ PRODUCED WITHIN A PLANT - A method for synthesizing influenza virus-like particles (VLPs) within a plant or a portion of a plant is provided. The method involves expression of influenza HA in plants and the purification by size exclusion chromatography. The invention is also directed towards a VLP comprising influenza HA protein and plants lipids. The invention is also directed to a nucleic acid encoding influenza HA as well as vectors. The VLPs may be used to formulate influenza vaccines, or may be used to enrich existing vaccines. | 09-23-2010 |
20110293650 | INFLUENZA VIRUS-LIKE PARTICLES (VLPS) COMPRISING HEMAGGLUTININ - A method for synthesizing influenza virus-like particles (VLPs) within a plant or a portion of a plant is provided. The method involves expression of influenza HA of type A/California/04/09 in plants and the purification by size exclusion chromatography. The invention is also directed towards a VLP comprising influenza HA protein of type A/California/04/09 and plants lipids. The invention is also directed to a nucleic acid encoding influenza HA of type A/California/04/09 as well as vectors. The VLPs may be used to formulate influenza vaccines, or may be used to enrich existing vaccines. | 12-01-2011 |
20130142826 | RECOMBINANT INFLUENZA VIRUS-LIKE PARTICLES (VLPS) PRODUCED IN TRANSGENIC PLANTS EXPRESSING HEMAGGLUTININ - A method for synthesizing influenza virus-like particles (VLPs) within a plant or a portion of a plant is provided. The method involves expression of influenza HA in plants and the purification by size exclusion chromatography. The invention is also directed towards a VLP comprising influenza HA protein and plant lipids. The invention is also directed to a nucleic acid encoding influenza HA as well as vectors. The VLPs may be used to formulate influenza vaccines, or may be used to enrich existing vaccines. | 06-06-2013 |
20130183341 | INFLUENZA VIRUS-LIKE PARTICLES (VLPS) COMPRISING HEMAGGLUTININ PRODUCED WITHIN A PLANT - A method for synthesizing influenza virus-like particles (VLPs) within a plant or a portion of a plant is provided. The method involves expression of influenza HA in plants and the purification by size exclusion chromatography. The invention is also directed towards a VLP comprising influenza HA protein and plant lipids. The invention is also directed to a nucleic acid encoding influenza HA as well as vectors. The VLPs may be used to formulate influenza vaccines, or may be used to enrich existing vaccines. | 07-18-2013 |
Sonia Trépanier, Saint-Nicolas CA
Patent application number | Description | Published |
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20100310604 | RECOMBINANT INFLUENZA VIRUS-LIKE PARTICLES (VLPS) PRODUCED IN TRANSGENIC PLANTS EXPRESSING HEMAGGLUTININ - A method for synthesizing influenza virus-like particles (VLPs) within a plant or a portion of a plant is provided. The method involves expression of influenza HA in plants and the purification by size exclusion chromatography. The invention is also directed towards a VLP comprising influenza HA protein and plants lipids. The invention is also directed to a nucleic acid encoding influenza HA as well as vectors. The VLPs may be used to formulate influenza vaccines, or may be used to enrich existing vaccines. | 12-09-2010 |
Sonia Tulyani, South Windsor, CT US
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20130089811 | SEAL ASSEMBLY AND METHOD FOR SELF-HEALING GLASS SEAL - A seal assembly includes first and second solid oxide fuel cell components and a self-healing glass between the components. The glass seal includes 35-60 wt % alkaline earth oxide, 2-15 wt % boron oxide, and 25-62 wt % silicone oxide. | 04-11-2013 |
Sonia Tulyani, Manchester, CT US
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20090107275 | Gear Having Improved Surface Finish - There is a gear set. The gear set has a) a first gear having a first surface and b) an intermeshing second gear having a second surface. The first and second surfaces each, independently, have an isotropic arithmetic mean roughness, Ra, of about 3 microinches or less and are lubricated. There is also a method for increasing the contact surface-fatigue life of a gear set. | 04-30-2009 |
20090254286 | Systems and Methods for Modeling Surface Properties of a Mechanical Component - There is a method for modeling the surface fatigue life of a mechanical component. The method has the following steps: a) modeling the surface fatigue life of the mechanical component on an atomistic scale to form an atomistic model, b) modeling the surface fatigue life of the mechanical component on a mesoscale to form a mesoscale model, c) modeling the surface fatigue life of the mechanical component on a macroscale to form a macroscale model, and d) testing the surface fatigue life of the mechanical component. Feedback from the macroscale model is employed at least once to validate the atomistic model. Feedback from the macroscale model is employed at least once to validate the mesoscale model. Feedback from the testing is employed at least once to validate the macroscale model. There is also an interactive, multiscale model for prediction surface fatigue life or degradation rate for a mechanical component. | 10-08-2009 |
20090324930 | PROTECTIVE COATINGS FOR SILICON BASED SUBSTRATES WITH IMPROVED ADHESION - An environmental coating system for silicon based substrates wherein a porous intermediate barrier layer having an elastic modulus of about 30 to 150 GPa is provided between a silicon metal containing bondcoat and a ceramic top environmental barrier layer. | 12-31-2009 |
20100119718 | Dense protective coatings, methods for their preparation and coated articles - A method for depositing a protective coating on a complex shaped substrate includes the steps of: (1) dipping a complex shaped substrate into a slurry to form a base coat thereon, the slurry comprising an aqueous solution, at least one refractory metal oxide, and at least one transient fluid additive present in an amount of about 0.1 percent to 10 percent by weight of the slurry; (2) curing the dipped substrate; (3) dipping the substrate into a precursor solution to form a top barrier coat thereon; and (4) heat treating the dipped, cured substrate to form a protective coating. | 05-13-2010 |
Sonia Vadrucci, Zurich CH
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20090280163 | High-Efficiency Fusogenic Vesicles, Methods of Producing Them, and Pharmaceutical Compositions Containing Them - The present invention relates to novel fusogenic vesicles as highly efficient and versatile encapsulation systems for delivering a substance of choice, such as nucleic acids, proteins, peptides, antigens, pharmaceutical drugs and cosmetic agents to cells and tissues. | 11-12-2009 |
Sonia Van Dooren, Meise BE
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20100311038 | NEAR FULL-GENOME ASSAY OF HCV DRUG RESISTANCE - The invention relates to assays for characterization of genotypic mutations of Hepatitis C Virus (HCV) showing a resistance to anti-HCV drugs. | 12-09-2010 |
20140187765 | NEAR FULL-GENOME ASSAY OF HCV DRUG RESISTANCE - Assays for characterization of genotypic mutations of Hepatitis C Virus (HCV) showing a resistance to anti-HCV drugs. | 07-03-2014 |
Sonia Zuniga Lucas, Madrid ES
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20090202588 | Nucleic acids encoding TGEV and PRRSV sequences for improved expression of PRRSV sequences - The present invention relates to nucleic acids comprising: | 08-13-2009 |
20120114683 | Nucleic Acid Encoding TGEV and PRRSV Sequences for Improved Expression of PRRSV Sequences - The present invention relates to nucleic acids comprising: | 05-10-2012 |