Caffrey, US
Andrew J. Caffrey, San Diego, CA US
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20100153184 | SYSTEM, METHOD AND COMPUTER PROGRAM PRODUCT FOR PREDICTING CUSTOMER BEHAVIOR - According to one aspect of the present disclosure a method and technique for predictive modeling of customer behavior is disclosed. The method includes receiving customer data from a plurality on non-affiliated vendor properties, anonymizing at least a portion of the received customer data and merging the anonymized customer data from each vendor property into a consortium database, and generating at least one predictive model of at least one behavior variable associated with at least one customer represented in the consortium database, the predictive model enabling identification of at least one stimuli likely to affect a desired response by the customer based on the predictive model. | 06-17-2010 |
Augustine J. Caffrey, Idaho Falls, ID US
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20140284490 | CHEMICAL DETECTION SYSTEM AND RELATED METHODS - A chemical detection system includes a frame, an emitter coupled to the frame, and a detector coupled to the frame proximate the emitter. The system also includes a shielding system coupled to the frame and positioned at least partially between the emitter and the detector, wherein the frame positions a sensing surface of the detector in a direction substantially parallel to a plane extending along a front portion of the frame. A method of analyzing composition of a suspect object includes directing neutrons at the object, detecting gamma rays emitted from the object, and communicating spectrometer information regarding the gamma rays. The method also includes presenting a GUI to a user with a dynamic status of an ongoing neutron spectroscopy process. The dynamic status includes a present confidence for a plurality of compounds being present in the suspect object responsive to changes in the spectrometer information during the ongoing process. | 09-25-2014 |
Cynthia L. Caffrey, Blairstown, NJ US
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20090146642 | Instrumentation Device and Interface Combining Multiple Elements - An instrumentation device having multiple elements includes at least one power supply module, a plurality of test and measurement instruments operatively coupled to the at least one power supply module and a user interface configured to select the at least one power supply module and to select at least one of the plurality of test and measurement instruments to provide power supply functionality and test and measurement functionality. | 06-11-2009 |
20090193275 | Quick-Stop Feature For Multiple Output Power Systems - A quick-stop feature built into power systems enables deactivating the power output of output supplies in the shortest possible time. This feature prevents damage to the power system and to the electrical devices connected to the output supplies. The quick-stop feature can be implemented as a hardware or a software solution. A button on the front panel of the power system can initiate the quick-stop feature. Alternatively, the power system can be connected to a network to watch over and provide fault protection mechanisms. A processor within the power system can execute the quick-stop feature by deactivating the power output. Deactivating the power output can follow a programmed shutdown, a sequenced shutdown or a complete shutdown. Downprogrammers ensure deactivating the power output in the shortest time. | 07-30-2009 |
Hugh M. Caffrey, Portland, OR US
James Caffrey, Carlsbad, CA US
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20120221432 | METHODS AND SYSTEMS FOR IN SILICO EXPERIMENTAL DESIGN AND FOR PROVIDING A BIOTECHNOLOGY PRODUCT TO A CUSTOMER - Provided herein is a method and computer program product for designing and/or simulating a biotechnology experiment in silico; and for providing and generating revenue from a customized list of one or more biotechnology products and/or services related to the in silico designed or simulated biotechnology experiment or the product of that experiment. In illustrative examples, the products and or services are indirectly related to a biomolecule designed by the in silico designed biotechnology experiment. In addition, provided herein is a method and computer system for generating revenue, that includes providing a customer with a first computer program product for designing or performing a biotechnology experiment in silico; and providing the customer with access to a purchase function for purchasing a second computer program product for designing or performing a biotechnology experiment in silico. Typically, functionality of the first computer product is less then and/or different than the functionality of the second computer product. | 08-30-2012 |
20150161702 | METHODS AND SYSTEMS FOR IN SILICO EXPERIMENTAL DESIGN AND FOR PROVIDING A BIOTECHNOLOGY PRODUCT TO A CUSTOMER - Provided herein is a method and computer program product for designing and/or simulating a biotechnology experiment in silico; and for providing and generating revenue from a customized list of one or more biotechnology products and/or services related to the in silico designed or simulated biotechnology experiment or the product of that experiment. In illustrative examples, the products and or services are indirectly related to a biomolecule designed by the in silico designed biotechnology experiment. In addition, provided herein is a method and computer system for generating revenue, that includes providing a customer with a first computer program product for designing or performing a biotechnology experiment in silico; and providing the customer with access to a purchase function for purchasing a second computer program product for designing or performing a biotechnology experiment in silico. Typically, functionality of the first computer product is less then and/or different than the functionality of the second computer product. | 06-11-2015 |
James L. Caffrey, Burelson, TX US
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20080242733 | (-)-Pseudoephedrine as a sympathomimetic drug - The present invention provides pharmaceutical compositions which include (−)-pseudoephedrine and a pharmaceutically acceptable carrier, wherein the (−)-pseudoephedrine is substantially-free of (+)-pseudoephedrine. In another embodiment, the present invention provides methods of relieving nasal and bronchial congestion and of inducing pupil dilation which include administering a pharmaceutically effective amount of (−)-pseudoephedrine to a mammal. The (−)-pseudoephedrine used in the present methods is substantially free of (+)-pseudoephedrine and also substantially free of side effects caused by administration of (+)-pseudoephedrine. | 10-02-2008 |
James M. Caffrey, Woodstock, NY US
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20090177924 | CONTEXT SENSITIVE DETECTION OF FAILING I/O DEVICES - Methods for context sensitive detection of failing I/O devices sample and record a response time of an I/O device for each of a first plurality of time intervals to generate a first plurality of sampled and recorded response times, and to determine whether or not at least one I/O error has occurred in each of the first plurality of time intervals. A mathematical model is applied which characterizes the first plurality of sampled and recorded response times. The mathematical model is applied in accordance with an I/O device category corresponding to the I/O device. The mathematical model provides a frame of reference for defining an I/O failure. | 07-09-2009 |
20100174947 | DAMAGED SOFTWARE SYSTEM DETECTION - A computer implemented method for a computer including a processor having a software stack accessed by multiple application programs includes receiving software requests from the multiple applications at the software stack; monitoring the rate of stack failures at the stack via a stack monitor; comparing the rate of stack failures with a time related threshold; and generating an alarm when the rate of stack failures exceeds the time related threshold. | 07-08-2010 |
20120096320 | SOFT FAILURE DETECTION - A method, system, and computer program product detect soft failures as follows. A set of artifacts being generated by at least one process in a system is monitored. A number of artifacts being generated by the process is determined to be below a given threshold in response to the monitoring. The process is monitored in response to the determination. A current state of the process is determined in response to the analyzing. A notification is generated in response to the current state of the process including a set of abnormal behaviors. | 04-19-2012 |
20120123991 | METHOD FOR DETERMINING A PREFERRED NODE IN A CLASSIFICATION AND REGRESSION TREE FOR USE IN A PREDICTIVE ANALYSIS - Techniques are described for determining what node of a classification and regression tree (CART) should be used by a predictive analysis application. A first approach is to use a standard deviation of the data at a given the level of the CART to determine whether data in the next, lower node is more consistent than the data in the current node. A second approach is to measure a correlation between data points in a given node and the time at which each point was sampled (or other correlation metric) to identify a preferred node. | 05-17-2012 |
20120209568 | MULTIPLE MODELING PARADIGM FOR PREDICTIVE ANALYTICS - Techniques are described for monitoring a performance metric. A multiple modeling approach is used to improve predictive analysis by avoiding the issuance of warnings during spikes which occur as a part of normal system processing. This approach increases the accuracy of predictive analytics on a monitored computing system, does not require creating rules defining periodic processing cycles, reduces the amount of data required to perform predictive modeling, and reduces the amount of CPU required to perform predictive modeling. | 08-16-2012 |
20120265723 | DETERMINING WHEN TO CREATE A PREDICTION BASED ON DELTAS OF METRIC VALUES - In an embodiment, deltas are calculated between respective current metric values for respective entities and previous metric values for the respective entities. A subset of the deltas is determined. A sum of the subset is calculated, and the sum is divided by a number of the subset to create an average delta for the subset. If one of the respective entities has one of the deltas that is greater than or equal to the average delta for the subset and the one of the respective entities was not previously used to create the previous prediction, then a current prediction is created. | 10-18-2012 |
20130061095 | SOFTWARE FAILURE DETECTION - A method detects soft failures as follows. A set of artifacts being generated by at least one process in a system is monitored. A number of artifacts being generated by the process is determined to be below a given threshold in response to the monitoring. The process is monitored in response to the determination. A current state of the process is determined in response to the analyzing. A notification is generated in response to the current state of the process including a set of abnormal behaviors. | 03-07-2013 |
20130086431 | MULTIPLE MODELING PARADIGM FOR PREDICTIVE ANALYTICS - Techniques are described for monitoring a performance metric. A multiple modeling approach is used to improve predictive analysis by avoiding the issuance of warnings during spikes which occur as a part of normal system processing. This approach increases the accuracy of predictive analytics on a monitored computing system, does not require creating rules defining periodic processing cycles, reduces the amount of data required to perform predictive modeling, and reduces the amount of CPU required to perform predictive modeling. | 04-04-2013 |
20130091385 | USER-COORDINATED RESOURCE RECOVERY - A computing system resource recovery method can include identifying a resource manager associated with a computing transaction, classifying the computing transaction to determine a predetermined metric, measuring an actual metric of the computing transaction, comparing the predetermined metric to the actual metric to detect abnormal behavior in the transaction and modeling the abnormal behavior to determine how the resource manager is affected by the abnormal behavior. | 04-11-2013 |
20130091391 | USER-COORDINATED RESOURCE RECOVERY - A computing system includes a processor configured to identify a resource manager associated with a computing transaction, classify the computing transaction to determine a predetermined metric, measure an actual metric of the computing transaction, compare the predetermined metric to the actual metric to detect abnormal behavior in the transaction and model the abnormal behavior to determine how the resource manager is affected by the abnormal behavior. | 04-11-2013 |
20130097109 | METHOD FOR DETERMINING A PREFERRED NODE IN A CLASSIFICATION AND REGRESSION TREE FOR USE IN A PREDICTIVE ANALYSIS - Techniques are described for determining what node of a classification and regression tree (CART) should be used by a predictive analysis application. A first approach is to use a standard deviation of the data at a given the level of the CART to determine whether data in the next, lower node is more consistent than the data in the current node. A second approach is to measure a correlation between data points in a given node and the time at which each point was sampled (or other correlation metric) to identify a preferred node. | 04-18-2013 |
John Justin Caffrey, Indianapolis, IN US
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20080247554 | Wireless Digital Transmission of Low Frequency Effects and Surround Channels For Surround Sound System - A subwoofer ( | 10-09-2008 |
Kevin Caffrey, Amityville, NY US
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20090063323 | SYSTEM AND METHOD FACILITATING TRI-PARTY REPURCHASE AGREEMENT TRANSACTIONS - In accordance with at least one embodiment of the invention, a DVP repo and tri-party repo hybrid transaction is provided as well as a process for facilitating and processing such a hybrid transaction, referred to herein as a “tri-party hybrid repo” transaction. | 03-05-2009 |
20110231307 | SYSTEM FACILITATING TRI-PARTY REPURCHASE AGREEMENT TRANSACTIONS - In accordance with at least one embodiment, a system configured to provide a collateral management service for tri-party hybrid repo transactions includes hardware and/or software for receiving, at a repo service provider, instructions specifying a tri-party hybrid repo transaction as well as a payable date for the tri-party hybrid repo transaction; hardware and/or software for transferring collateral that is the subject of the tri-party hybrid repo transaction on or prior to the payable date to a buyer/investor for the tri-party hybrid repo transaction in the buyer/investor's Securities Account at the Federal Reserve Bank via the Fedwire Securities Service and free of payment or versus payment; and hardware and/or software for returning collateral on or prior to the payable date to the broker/dealer/seller for the tri-party hybrid repo transaction via the repo service provider versus payment via the Fedwire Securities Service. | 09-22-2011 |
Kevin Caffrey, New York, NY US
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20090262913 | System and Method For Tracking Call Activity To A Set Of Advertised Businesses - A system and method for tracking call activity of a plurality of businesses is disclosed. A global pool of phone numbers is allocated from which to draw numbers. A business-specific pool of numbers is established for business locations involved in advertisements using the Internet via Web pages. As a consumer begins viewing an advertisement for a business, a number is temporarily allocated from the business's pool of available numbers. As the business's pool of unallocated numbers is exhausted, a metric is used to determine whether or not to grow the pool of numbers, to show an untracked ‘fallback’ number for the business, or to reuse a previously allocated number. When one of the temporarily allocated numbers is called, the online consumer it was associated with is credited for making the call and the business is credited and charged for receiving the call. This method of allocating and presenting numbers with all numbers ultimately being tied to the same business ensures that even if a consumer calls a number much later after it has been re-allocated, that the number will still ring to the correct business. | 10-22-2009 |
20110019808 | METHOD AND SYSTEM FOR AUTOMATIC ASSIGNMENT OF OUTBOUND AND INBOUND CALL IDENTITY - A system and method for automatic assignment of outbound and inbound call identity between a salesperson and a client is disclosed. For automatic assignment of outbound call identity between a salesperson and a client, a salesperson places a call to the telephone number of the client. A phone server matches a sales group to a salesperson and an entered sales group and an NPA (i.e., area code) of the client in a database. If a match is found, the phone server substitutes a replacement caller ID for actual caller ID of the salesperson. When the client answers the call, the replacement caller ID or default caller ID is displayed on client's phone. For automatic assignment of inbound call identity between a client and a salesperson, the client places a call using the replacement caller ID. The phone server searches the database for a sales group that matches the DID of the replacement caller ID. The phone server rings the telephones of salespeople that match the sales group entry in order of the most “efficient” salesperson of the group until one of the salespeople answers their phone. | 01-27-2011 |
20110026689 | TELEPHONE CALL INBOX - A system and method for extracting and presenting useful data from calls received by a client is disclosed. The resulting “telephone call inbox” is a way for a client view pay per call advertising as a stream of consumers with information available to understand the call activity of the consumers and for the client to navigate their call history. The system automatically filters non-consumer fraudulent calls, extracts the identity of a consumer, aggregates several calling entities into a single consumer, transcribes the call into a call stream using voice recognition software, extracts patterns and draws conclusions from the call stream, and presents a list of call streams in a user friendly set of web pages configured as the telephone call inbox. The telephone call inbox includes, for each call, the caller ID, one or more key words, phrases or major conclusions concerning the call, and the voice recognized call stream. | 02-03-2011 |
20110060611 | MEDIA OPTIMIZATION USING TRANSCRIPTION ANALYSIS - A system and method for optimizing the price of a call to a business and the placement of a business' information within an ad buy on a Web page are disclosed. A call is received by a client from a potential consumer of a product. The call is transcribed into a text call stream on both the consumer and the client sides of the call. Patterns are extracted from the call. The patterns extracted may be applied against patterns relevant to the client. Patterns relevant to the client may be tied to certain goals of the business of the client that indicate successful business transactions between the consumer and the client or that indicate a service provide by the client. Extracted patterns may be used to adjust the price of the call based on the client's willingness to pay for a call containing patterns relevant to the client. | 03-10-2011 |
20120213350 | SYSTEM AND METHOD FOR TRACKING CALL ACTIVITY TO A SET OF ADVERTISED BUSINESSES - A system and method for tracking call activity of a plurality of businesses is disclosed. A global pool of phone numbers is allocated from which to draw numbers. A business-specific pool of numbers is established for business locations involved in advertisements using the Internet via Web pages. As a consumer begins viewing an advertisement for a business, a number is temporarily allocated from the business's pool of available numbers. As the business's pool of unallocated numbers is exhausted, a metric is used to determine whether or not to grow the pool of numbers, to show an untracked ‘fallback’ number for the business, or to reuse a previously allocated number. When one of the temporarily allocated numbers is called, the online consumer it was associated with is credited for making the call and the business is credited and charged for receiving the call. | 08-23-2012 |
20130287194 | MEDIA OPTIMIZATION USING TRANSCRIPTION ANALYSIS - A system and method for optimizing the price of a call to a business and the placement of a business' information within an ad buy on a Web page are disclosed. A call is received by a client from a potential consumer of a product. The call is transcribed into a text call stream on both the consumer and the client sides of the call. Patterns are extracted from the call. The patterns extracted may be applied against patterns relevant to the client. Patterns relevant to the client may be tied to certain goals of the business of the client that indicate successful business transactions between the consumer and the client or that indicate a service provide by the client. Extracted patterns may be used for targeting of advertisements based on a call containing patterns relevant to the client. | 10-31-2013 |
20150278867 | BEACON DEVICE FOR ENHANCING MEASUREMENTS OF THE EFFECITIVENESS OF MOBILE NOTIFICATIONS - A beacon device comprising a memory, a processor, and one or more first wireless transceivers is disclosed. The processor retrieves, from the memory, a list of entries of identification information related to a plurality of entities. The processor selects the one or more first wireless transceivers. The processor divides the list of entries of identification information into one or more sub-lists. Each of the one or more sub-lists corresponds to a selected one of the first wireless transceivers. The processor instructs the selected one or more first wireless transceivers to repeatedly cycle through broadcasting each of the entries in the designated sub-list in successive first time intervals. The transmitted entries are to be received and to be processed by one or more receiving devices in a second time interval equal to or greater than a minimum beacon broadcast interval. | 10-01-2015 |
Leo George Caffrey, Katy, TX US
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20130277060 | ASSEMBLIES, SYSTEMS AND METHODS FOR INSTALLING MULTIPLE SUBSEA FUNCTIONAL LINES - Disclosed are methods for installing at least two subsea functional lines having differing functions, such as a subsea umbilical and a subsea flowline, and integrated termination assemblies for use in the methods. The integrated termination assemblies combine terminations of the at least two subsea functional lines, simplifying the layout of a subsea production field, reducing the number of connections necessary and simplifying the installation of subsea functional lines used in offshore hydrocarbon production. | 10-24-2013 |
Michael Paul Caffrey, Los Alamos, NM US
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20110255571 | ENERGY EFFICIENCY IN WIRLESS COMMUNICATION SYSTEMS - Wireless communication systems and methods utilize one or more remote terminals, one or more base terminals, and a communication channel between the remote terminal(s) and base terminal(s). The remote terminal applies a direct sequence spreading code to a data signal at a spreading factor to provide a direct sequence spread spectrum (DSSS) signal. The DSSS signal is transmitted over the communication channel to the base terminal which can be configured to despread the received DSSS signal by a spreading factor matching the spreading factor utilized to spread the data signal. The remote terminal and base terminal can dynamically vary the matching spreading factors to adjust the data rate based on an estimation of operating quality over time between the remote terminal and base terminal such that the amount of data being transmitted is substantially maximized whilst providing a specified quality of service. | 10-20-2011 |
Michael S. Caffrey, Tucson, AZ US
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20140151960 | GAMING SYSTEM USING GAMING SURFACE HAVING COMPUTER READABLE INDICIA AND METHOD OF USING SAME - A gaming system is provided having a plurality of playing positions, with each playing position having both a human readable and a machine readable indicia identifying the playing position. The gaming system also includes playing pieces, which also have both human and machine readable indicia. The gaming system uses a smart phone with an optical scanner to facilitate interaction with the gaming surface and pieces. | 06-05-2014 |
Paul O. Caffrey, Roanoke, VA US
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20090280012 | WIND TURBINE WITH WIRELESS PITCH CONTROL - A wind turbine includes wireless system for receiving a control signal at a hub of the wind turbine. | 11-12-2009 |
20130176893 | Loop Containment Enhancement - Systems, methods, and apparatus for providing a communication network free of bridge loops by providing a first message from one of two bridges and a second message in response to the first message from the other of the two bridges and establishing a communicative path if both the first and second messages were received. | 07-11-2013 |
20130177022 | Dynamic Virtual LANs to Segregate Data - Systems, methods, and apparatus for receiving commands and controlling allocation of ports of a communications switch to one or more virtual local area networks (VLANs). | 07-11-2013 |
20130189485 | Micro-Structure and Nano-Structure Replication Methods and Article of Manufacture - A method for the replication of a textured surface of a master is disclosed, in which the textured surface of the master is comprised of micron-scale cones having nano- or micro-scale surface features. Alternatively, the master may be comprised of micron-scale structures, nano-scale structures, and micron scale structures having nano-scale surface features. Replication can be achieved through a molding or embossing technique. Using these technique, the textured surface of the master is faithfully replicated onto the surface of the replica. A number of representative materials and additional processing steps are also disclosed. The replicated texture exhibits many useful properties, including enhanced hydrophobicity and reduced light reflection properties, making the disclosed method a simple and attractive alternative to existing texturing techniques. | 07-25-2013 |
Paul Oliver Caffrey, Roanoke, VA US
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20110082570 | CONTROL SYSTEMS AND METHODS OF PROVIDING THE SAME - Control systems and methods for controlling certain systems, devices, and apparatus are described. A control system may include a memory and at least one processor. The memory may be operable to store both a Foundation Fieldbus protocol that facilitates communication with one or more Foundation Fieldbus devices and a second protocol that facilitates communication with one or more control devices. The at least one processor may be operable to access both the Foundation Fieldbus protocol and the second protocol, and to control the one or more Foundation Fieldbus devices and the one or more control devices. A network may facilitate communications between the at least one processor and both the one or more Foundation Fieldbus devices using the Foundation Fieldbus protocol and the one or more control devices using the second protocol. | 04-07-2011 |
20120030372 | REDUNDANT ETHERNET CONNECTION SYSTEM AND METHOD - A system includes a first communication network including a first switch and a second switch connected to the first switch, a second communication network including a third switch and fourth switch coupled to the third switch, and a first computing device coupled to the first communications network through a first network interface controller (NIC) and coupled to the second communication network through a second NIC. The first computing device is configured to communicate through the first NIC first communication network until it determines that it is not receiving bridge protocol data units (BPDUs) and then to communicate through the second NIC. | 02-02-2012 |
20130018490 | Web-Based Operator Control Interface to Generator Control SystemsAANM Caffrey; Paul OliverAACI RoanokeAAST VAAACO USAAGP Caffrey; Paul Oliver Roanoke VA USAANM Casteel; Jordan BrantleyAACI RoanokeAAST VAAACO USAAGP Casteel; Jordan Brantley Roanoke VA USAANM Damodar; Dhanashree SadanandAACI MumbaiAACO INAAGP Damodar; Dhanashree Sadanand Mumbai INAANM Fowley; Douglas GreggAACI RoanokeAAST VAAACO USAAGP Fowley; Douglas Gregg Roanoke VA USAANM Jackson; RoyAACI RoanokeAAST VAAACO USAAGP Jackson; Roy Roanoke VA USAANM Pearson; William RobertAACI RoanokeAAST VAAACO USAAGP Pearson; William Robert Roanoke VA US - A web-based operator control interface system can include an operator interface section including a web browser application, a generator exciter section or a static starter section coupled to the operator interface section, a generator coupled to the generator exciter section and a web server application configured to receive processing requests from the web browser application, and further configured to internally process real-time generator functions. | 01-17-2013 |
20130096856 | SYSTEMS AND METHODS FOR ADAPTIVE POSSIBLE POWER DETERMINATON IN POWER GENERATING SYSTEMS - A system for determining the output capacity of a power generating system including a sensor that monitors at least one condition of the power generating system and outputs the monitored condition data, and a power capability determination device that dynamically determines a full capacity of the power generating system based upon the outputted environmental data from the electronic controller. | 04-18-2013 |
Rebecca Caffrey, Richmond, VA US
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20140303228 | Biomarkers for Amyotrophic Lateral Sclerosis and Methods Using the Same - The disclosure provides biomarkers of amyotrophic lateral sclerosis (ALS). The disclosure also provides various methods of using the biomarkers, including methods for diagnosis of ALS, methods of determining predisposition to ALS, methods of monitoring progression/regression of ALS, methods of assessing efficacy of compositions for treating ALS, methods of screening compositions for activity in modulating biomarkers of ALS, methods of treating ALS, as well as other methods based on biomarkers of ALS. | 10-09-2014 |
Rebecca Caffrey, Mountain View, CA US
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20120172356 | SERUM BIOMARKERS FOR CHAGAS DISEASE - The present invention provides protein-based biomarkers and biomarker combinations that are useful in qualifying Chagas disease status in a patient. In particular, the biomarkers of this invention are useful to classify a subject sample as infected with Chagas disease or non-infected. The biomarkers can be detected by SELDI mass spectrometry. | 07-05-2012 |
Rebecca Caffrey, N Chesterfield, VA US
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20140324460 | METHOD FOR DETERMINING AND MANAGING TOTAL CARDIODIABETES RISK - A method for generating a report presenting a patient-specific information relevant to assessing a patient's cardiodiabetes risk to guide and allow a physician or healthcare provider in the choice of therapy or therapies that will be maximally effective for a specific patient, to monitor the response to the chosen therapy and reduce the patient's risk of developing cardiodiabetes and/or its complications. | 10-30-2014 |
Rebecca E. Caffrey, N Chesterfield, VA US
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20130316926 | METHOD FOR THE MONITORING OF SMOKING CESSATION COMPLIANCE AND RECOVERY, THERAPEUTIC INTERVENTION, AND RISK MANAGEMENT - The invention provides compositions and methods for determining patient compliance with a smoking cessation program, and monitoring the patient for physiological recovery from the deleterious effects of smoking, with particular emphasis on those effects that impact risk of cardiovascular disease and development of cancer. The invention also provides compositions and methods for treating a subject according to the patient compliance with the smoking cessation program. | 11-28-2013 |
20140200177 | METHOD OF DETECTION OF OCCULT PANCREATIC BETA CELL DYSFUNCTION IN NORMOGLYCEMIC PATIENTS - This invention relates to a method for detecting the presence of or likelihood of a patient of developing occult pancreatic beta cell dysfunction, and a method for detecting the presence of or likelihood of a patient of developing clinically significant post-prandial hyperglycemia. The methods involve (a) measuring a level of alpha-hydroxybutyrate (AHB) in a single fasting baseline biological sample of the patient; (b) comparing the level of AHB in the single fasting baseline biological sample to a reference AHB level; and (c) determining the presence of or likelihood of developing the disorder in the patient based on the comparison in step (b). An increased AHB level at fasting baseline indicates that a normoglycemic, normo-insulinemic and/or non-dyslipidemic patient has developed or has an increased likelihood of developing occult pancreatic beta cell dysfunction. An increased AHB level at fasting baseline and an elevated glucose level of at least about 155 mg/dL at 30 minutes and/or 1 hour indicates that a normoglycemic, normo-insulinemic and/or non-dyslipidemic patient has developed or has an increased likelihood of developing clinically significant post-prandial hyperglycemia. | 07-17-2014 |
20140200178 | METHOD OF DETECTION OF CLINICALLY SIGNIFICANT POST-PRANDIAL HYPERGLYCEMIA IN NORMOGLYCEMIC PATIENTS - This invention relates to a method for detecting the presence of or likelihood of a patient of developing occult pancreatic beta cell dysfunction, and a method for detecting the presence of or likelihood of a patient of developing clinically significant post-prandial hyperglycemia. The methods involve (a) measuring a level of alpha-hydroxybutyrate (AHB) in a single fasting baseline biological sample of the patient; (b) comparing the level of AHB in the single fasting baseline biological sample to a reference AHB level; and (c) determining the presence of or likelihood of developing the disorder in the patient based on the comparison in step (b). An increased AHB level at fasting baseline indicates that a normoglycemic, normo-insulinemic and/or non-dyslipidemic patient has developed or has an increased likelihood of developing occult pancreatic beta cell dysfunction. An increased AHB level at fasting baseline and an elevated glucose level of at least about 155 mg/dL at 30 minutes and/or 1 hour indicates that a normoglycemic, normo-insulinemic and/or non-dyslipidemic patient has developed or has an increased likelihood of developing clinically significant post-prandial hyperglycemia. | 07-17-2014 |
Rebecca E. Caffrey, North Chesterfield, VA US
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20140274891 | METHOD OF GENERATING AN INDEX SCORE FOR MBL DEFICIENCY TO PREDICT CARDIODIABETES RISK - This application relates to methods of predicting susceptibility or likelihood of a clinically-relevant mannose-binding lectin (MBL)-deficient subject to develop a cardiovascular disease and/or cardiodiabetes. The methods include measuring MBL mass or concentration and, optionally, measuring MBL activity, at least one other biomarker and/or genotyping of MBL gene and its promoters; combining the information obtained into a calculated MBL-inclusive index score that involves mathematical transformation; and assigning a risk of cardiadiabetic status and clinical endpoints based on the determination and comparison of the MBL inclusive index to reference values from a population. | 09-18-2014 |
20140274975 | METHOD OF DETERMINING PRIOR HISTORY OF ISCHEMIC STROKE FOR CURRENT RISK EVALUATION AND THERAPY GUIDANCE - The invention provides methods and compositions for diagnosing prior ischemic stroke or transient ischemic attack (TIA) and approximate the time said stroke occurred, comprising measurement of IgG and IgM antibodies to NR2A and/or NR2B NMDA receptor or fragment thereof in a biological sample, and comparing those measurements to reference population standards and to each other. The invention also includes optionally measuring other biomarkers for autoimmune disease for the reduction in false positives and better risk stratification for future stroke events. The method is particularly useful for identifying individuals that are at risk for future stroke or TIA, and for diagnosing previous history of ischemic stroke or TIA. This measurement and comparison enables determination of the risk of future stroke which is by definition higher in those patients who have suffered a previous stroke. The determining of existence of previous stroke and risk level of future stroke enable optimal therapeutic decisions to reduce risk of future events. | 09-18-2014 |
Stephen John Caffrey, Rochester, NY US
Patent application number | Description | Published |
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20120133065 | REAL-TIME, CLOSED-LOOP SHAPE CONTROL OF EXTRUDED CERAMIC HONEYCOMB STRUCTURES - Systems and methods for real-time, closed-loop shape control of extruded ceramic honeycomb structures are disclosed. Methods include extruding batch material through an extruder barrel and through an extruder die using at least one extrusion screw to form the extrudate, and measuring a shape of the extrudate immediately adjacent the die. The batch material water content is determined or measured, at least one of the extruder barrel and screw temperature are measured, and the extrusion screw rotation rate are measured. At least one of the batch material water content, barrel temperature, screw temperature and rotation rate is adjusted to maintain the extrudate shape to within a select tolerance. | 05-31-2012 |
Tom Caffrey, Bellevue, NE US
Patent application number | Description | Published |
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20100190720 | Compositions and Methods for Preventing or Treating Cancer - The present invention relates to a MUC1 cytoplasmic tail peptide or portion thereof. These peptides are useful for inducing an immune response to MUC1-expressing tumor cells and thus for preventing or treating cancer. | 07-29-2010 |
20120270798 | Compositions and Methods for Preventing or Treating Cancer - The present invention relates to a MUC1 cytoplasmic tail peptide or portion thereof. These peptides are useful for inducing an immune response to MUC1-expressing tumor cells and thus for preventing or treating cancer. | 10-25-2012 |