52nd week of 2010 patent applcation highlights part 60 |
Patent application number | Title | Published |
20100331675 | PROCESS FOR ACQUIRING A THREE-DIMENSIONAL RADIOLOGICAL IMAGE OF AN ORGAN IN MOVEMENT - An embodiment of the invention relates to a process for acquiring a three-dimensional radiological image of an organ in movement of a patient, according to which a control unit executes steps of: ( | 2010-12-30 |
20100331676 | GAMMA PROBE DETECTION OF AMYLOID PLAQUE USING RADIOLABELED A-BETA BINDING COMPOUNDS - The present invention relates to a method of detecting β-amyloid peptide aggregates in the brain of an individual and kits thereto. The method includes administering to an individual an effective amount of an Aβ-binding radiopharmaceutical, waiting a period of time, measuring a gamma radiation count over an external area of the head corresponding to the cortex of the individual using a radiation detection device, and comparing the gamma radiation count with a control gamma radiation count. | 2010-12-30 |
20100331677 | MARKER DELIVERY SYSTEM - A marker delivery system including a surgical needle defining a lumen. The surgical needle is adapted to receive a marker. The surgical needle includes a side opening substantially adjacent to a first end of the surgical needle. The marker delivery system also includes a plunger insertable into the surgical needle at a second end of the surgical needle. Depression of the plunger inside the lumen of the surgical needle pushes the marker through the side opening of the surgical needle. | 2010-12-30 |
20100331678 | Multi-Syringe Power Injector using Single Drive Ram - A power injector ( | 2010-12-30 |
20100331679 | PULSED ECHO SENSING DEVICE AND METHOD FOR AN ORTHOPEDIC JOINT - At least one embodiment is directed to a sensor for measuring a skeletal system. A signal path of the system comprises an amplifier ( | 2010-12-30 |
20100331680 | HIGH PRECISION PROCESSING OF MEASUREMENT DATA FOR THE MUSCULAR-SKELETAL SYSTEM - A measurement system measures a parameter of a muscular-skeletal system. The measurement system is placed in proximity to the muscular-skeletal system such that the parameter to be measured is applied to a sensing assemblage ( | 2010-12-30 |
20100331681 | ZERO-CROSSING RECEIVER FOR ORTHOPEDIC PARAMETER SENSING - A sensor system uses positive closed-loop feedback to provide energy waves into a medium. It comprises a transducer ( | 2010-12-30 |
20100331682 | DEVICE AND METHOD FOR ADVANCED LOW-POWER MANAGEMENT OF A SENSOR TO MEASURE A PARAMETER OF THE MUSCULAR-SKELETAL SYSTEM - A sensing insert device ( | 2010-12-30 |
20100331683 | SENSING MODULE FOR ORTHOPEDIC LOAD SENSING INSERT DEVICE - A sensing insert device ( | 2010-12-30 |
20100331684 | Method and Apparatus For Determining The Absolute Value Of Intracranial Pressure - A method and apparatus for obtaining the absolute value of intracranial pressure in a non-invasive manner is described by using an ultrasonic Doppler measuring device which detects the intracranial and extracranial blood flow velocities of the intracranial and extracranial segments of the ophthalmic artery. The eye in which the blood flow is monitored is subjected to an external pressure, sufficient to equalize the intracranial and extracranial angle-independent blood flow factors calculated from the intracranial velocity signal and extracranial velocity signal. The absolute value of the intracranial pressure is identified as that external pressure at which such equalization occurs. | 2010-12-30 |
20100331685 | TRANSDUCER DRIVER FOR MEASURING A PARAMETER OF THE MUSCULARSKELETAL SYSTEM - A measurement system for capturing a transit time, phase, or frequency of energy waves propagating through a propagation medium is disclosed. The measurement system comprises two different closed-loop feedback paths. The first path includes a transducer driver ( | 2010-12-30 |
20100331686 | System for Treatment and Imaging Using Ultrasonic Energy and Microbubbles and Related Method Thereof - A method and related system for providing therapy to a treatment site, such as stenosis or other vasculature disease, at one or more locations of a subject, such as the vasculature. The method includes: advancing an ultrasound catheter to or in proximity to the subject's treatment site; infusing microbubbles into or proximal to the treatment site; and delivering ultrasonic energy from the ultrasound catheter. The ultrasonic energy may be adapted for: imaging the treatment site, translating the microbubbles into or in the vicinity of the treatment site and/or rupturing the microbubbles. | 2010-12-30 |
20100331687 | SYSTEM FOR CONTINUOUS WAVE, PULSED, AND PULSED-ECHO PARAMETER MEASUREMENT - A measurement system for capturing a transit time, phase, or frequency of energy waves propagating through a propagation medium is disclosed. The measurement system comprises two different closed-loop feedback paths. The first path includes a driver circuit ( | 2010-12-30 |
20100331688 | AUTOMATIC DIAGNOSIS SUPPORT APPARATUS, ULTRASONIC DIAGNOSIS APPARATUS, AND AUTOMATIC DIAGNOSIS SUPPORT METHOD - Certain embodiments provide an automatic diagnosis support apparatus includes extracting a plurality of parameters associated with a predetermined object by using medical information acquired by a medical image diagnosis apparatus and extracting the plurality of parameters for each disease associated with a disable-bodied person by using medical information associated with the disable-bodied person, calculating a ruler associated with each disease case by executing an MT system using the plurality of parameters for each disease associated with the disable-bodied person, calculating a distance between the object and a state space of the disable-bodied person associated with the each disease by executing the MT system using a plurality of parameters associated with the object, determining a disease type of the object by using the ruler and a distance between the object and a state space of a disable-bodied person, and generating diagnosis support information based on the determination result. | 2010-12-30 |
20100331689 | POST-BEAMFORMING COMPRESSION IN ULTRASOUND SYSTEMS - In an ultrasound imaging system that applies a beamformer to received ultrasound signal samples to form one or more beams represented by arrays of beamformed samples, a method and an apparatus compress each array of beamformed samples independently of the other arrays to form compressed beams. A plurality of analog to digital converters sample multiple analog ultrasound signals produced by a transducer array to provide multiple streams of ultrasound signal samples to the beamformer. The compressed beams are transferred via a digital interface to a signal processor. At the signal processor, the compressed beams are decompressed to form decompressed beams. The signal processor further processes the decompressed beams for diagnostic imaging, such as for B-mode and Doppler imaging, and scan conversion to prepare the resulting ultrasound image for display. This abstract does not limit the scope of the invention as described in the claims. | 2010-12-30 |
20100331690 | Systems and Techniques for Providing Elasticity Graphs - An elastogram device comprises a driver controller including a wave generator, and an amplifier assembly receiving waves from the wave generator for driving an actuator, the amplifier assembly compatible with at least one pneumatic actuator, at least one hydraulic actuator, at least one piezoelectric actuator, and at least one electromechanical actuator, an elastogram processor receiving a wave image from an imaging source and generating an elastogram from the wave image, and a user input and output assembly including a display rendering the elastogram, a user interface providing a plurality of options for selection, the options including selectable parameters to control the wave generator and to generate the elastogram. | 2010-12-30 |
20100331691 | ULTRASONIC DIAGNOSIS APPARATUS AND ULTRASONIC DIAGNOSIS SUPPORT INFORMATION PROVIDING METHOD - Certain embodiments provide an ultrasonic diagnosis apparatus includes acquiring ultrasonic image data corresponding to each time phase in a first interval including at least one contraction and one stretching by scanning a diagnosis region of an object which repeats a contracting motion and a stretching motion, with an ultrasonic wave, accompanying application of a dynamic load including repetitive contraction and relaxation, over the first interval, generating velocity information of the diagnosis region associated with the contracting motion and the stretching motion by using the ultrasonic image data corresponding to each time phase in the first interval, deciding reference information as a reference for a period of the dynamic load by using the velocity information, and generating support information for supporting operation of applying the dynamic load by using the reference period and outputting the information in a predetermined form. | 2010-12-30 |
20100331692 | ULTRASOUND DIAGNOSIS APPARATUS AND METHOD OF SETTING SOUND VELOCITY - In one embodiment, an ultrasonic diagnostic apparatus includes an image creating unit, an image-creation control unit and a display control unit. The image creating unit creates an ultrasound image from data created by adding a reflected wave signal of an ultrasound wave transmitted to an imaging target portion of a subject by using a reception delay time calculated from a set sound velocity set as a sound velocity in the imaging target portion. The image-creation control unit switches a set sound velocity set at a present moment in a variable range, and controls the image creating unit so as to create a plurality of ultrasound images each using a reception delay time corresponding to each of the set sound velocities to be switched. The display control unit controls display such that the ultrasound images created are displayed on a certain display unit. | 2010-12-30 |
20100331693 | ULTRASOUND IMAGE DIAGNOSIS APPARATUS AND A CONTROL METHOD FOR MEASURING DIAGNOSIS PARAMETERS - An ultrasound image diagnosis apparatus that can display image data acquired at a plurality of measuring positions in panoramic image data and display measured results of diagnosis parameters for each of the measuring positions of the panoramic image data The panoramic image data is generated by combining a plurality of reference image data generated at a plurality of diagnosis target positions. The plurality of measuring positions is designated based on the latest reference image data composing the panoramic image data. Based on Doppler signals acquired through ultrasound transmissions and receptions to and from the plurality of measurement positions, image data is generated. | 2010-12-30 |
20100331694 | ULTRASONIC DIAGNOSTIC APPARATUS. - An ultrasonic diagnostic apparatus that can display various information obtained by acquiring an elasticity image in association with the elasticity image or a biometric simulation image is implemented. The ultrasonic diagnostic apparatus | 2010-12-30 |
20100331695 | Plaque Characterization Using Multiple Intravascular Ultrasound Datasets Having Distinct Filter Bands - A system and method are disclosed that facilitate generating visual representations of characterized tissue based upon ultrasound echo information obtained from a portion of an imaged body. The system includes a first filter having a first filter band that is applied to a near range portion of the ultrasound echo information to render near range filtered echo information. A second filter, having a second filter band that covers a frequency range of the first filter band, is applied to a far range portion of the ultrasound echo information to render far range filtered echo information. The system furthermore includes a set of characterization criteria that are applied to the near and far range filtered echo information. The characterized near and far range image data are thereafter combined into a single tissue-characterization image. | 2010-12-30 |
20100331696 | APPARATUS AND METHOD FOR AUTOMATICALLY MEASURING THE VOLUME OF URINE IN A BLADDER USING ULTRASOUND SIGNALS - The method of accurately measuring the volume of urine in a bladder includes the steps of; generating a plurality of ultrasound scan planes using the received ultrasound signals; detecting distances between the front and back walls of the bladder for each scan line in the ultrasound scan planes; determining an area of the bladder using the detected distances of the scan lines for each ultrasound scan plane; generating a virtual radius of the bladder using the determined area of the bladder for each ultrasound scan plane; determining a calibration coefficient for each ultrasound scan plane using the detected distances of the scan lines; calibrating the virtual radius of the bladder for each ultrasound scan plane using the calibration coefficient; determining the volume of urine in the bladder by calculating the volume of a sphere of which the radius is the average of the calibrated virtual radii for the ultrasound scan planes. The method can accurately measure the volume of urine in a bladder using ultrasound signals regardless of the detection location on which a transducer is placed. | 2010-12-30 |
20100331697 | ECHOGENIC NEEDLE CATHETER CONFIGURED TO PRODUCE AN IMPROVED ULTRASOUND IMAGE - An echogenic medical device, such as a needle catheter, which produces an improved ultrasonic image of the device, and a method of performing a medical procedure using a device of the invention. One aspect is directed to a catheter which reduces artifacts in the ultrasound image of the catheter. In one embodiment, the catheter has a spherical distal tip. Another aspect of the invention is directed to an echogenic catheter with echogenic portions arranged in an array to facilitate determination by ultrasonic imaging of the rotational orientation of the catheter relative to a desired location within the patient. | 2010-12-30 |
20100331698 | ULTRASONIC DIAGNOSTIC APPARATUS, ULTRASONIC ELASTICITY INFORMATION PROCESSING METHOD AND ULTRASONIC ELASTICITY INFORMATION PROCESSING PROGRAM - An ultrasonic diagnostic apparatus characterized by comprising: an ultrasonic probe for transmitting/receiving an ultrasonic wave to/from an object; a phasing and summing unit for generating RF signal frame data of a cross-sectional site of the object on the basis of a reflection echo signal measured by the ultrasonic probe; an elasticity calculator for generating frame data of elasticity information representing the degree of hardness or softness of a tissue at each measurement point of the cross-sectional site on the basis of a pair of RF signal frame data acquired in different times; a weighting unit for weighting the elasticity information of each measurement point of the generated elasticity frame data in accordance with the degree of sharpness of a distribution of elasticity information for plural measurement points containing adjacent measurement points; a smoothing unit for smoothing the weighted elasticity information of the plurality of elasticity frame data generated at the different times; and an elasticity image display unit for generating an elasticity image on the basis of the smoothed elasticity frame data and displaying the generated elasticity image on a display unit. | 2010-12-30 |
20100331699 | Full-field breast ultrasound system and architecture - A modular, flexible architecture for offering full-field breast ultrasound (FFBU) functionality and general-purpose ultrasound functionality in a single system is described. A conventional, general-purpose ultrasound system ( | 2010-12-30 |
20100331700 | ULTRASONIC DIAGNOSIS APPARATUS, AUTOMATIC SUPPORT APPARATUS, AND AUTOMATIC SUPPORT METHOD - According to one embodiment, an ultrasonic diagnosis apparatus includes a storage unit, a ultrasonic probe, a transmission/reception unit, a measured value calculation unit, a distance calculation unit, and a determination unit. The storage unit stores data of a state space based on a first measured values of a measurement item associated with an able-bodied person. The transmission/reception unit transmits ultrasonic waves to a subject via an ultrasonic probe, and generates reception signals corresponding to an ultrasonic waves reflected by the subject. The measured value calculation unit calculates a second measured value of the measurement item associated with the subject based on the reception signals. The distance calculation unit calculates a Mahalanobis distance of the subject based on the state space and the second measured value. The determination unit compares the Mahalanobis distance with a threshold to determine whether the subject has the disease evaluated by the measurement item. | 2010-12-30 |
20100331701 | THREE-DIMENSIONAL ULTRASONIC DIAGNOSIS APPARATUS - According to one embodiment, an ultrasonic diagnosis apparatus includes an ultrasonic probe and an ultrasonic scanning unit configured to repeatedly scan an interior of an subject with an ultrasonic wave via the ultrasonic probe and repeatedly acquire echo signals. An image generation unit generates data of blood flow images based on the echo signals. An interpolation processing unit identifies at least one pixel in which clutter components occupy the majority of the pixel value, and to interpolate a pixel value of the identified pixel based on pixel values of at least two other blood flow images corresponding to a substantially same cardiac phase as that of the blood flow image including the identified pixel. | 2010-12-30 |
20100331702 | ULTRASONIC PROBE AND ULTRASONIC DIAGNOSTIC APPARATUS - According to one embodiment, an ultrasonic probe includes a probe unit and cooling unit. The probe unit is obtained by arranging, in a housing, a transducer unit which transmits and receives ultrasonic waves with an object to be examined, an electronic circuit unit which is connected to the transducer unit and performs electrical signal processing, and a heat transfer member which is made of a material having a heat transfer coefficient higher than that of the electronic circuit unit, and transfers heat of the electronic circuit unit to a housing surface. The cooling unit is detachably mounted on the housing of the probe unit, and cools the heat transfer member by passing a coolant in a channel formed inside the cooling unit. | 2010-12-30 |
20100331703 | ULTRASOUND TRANSDUCER DRIVE CIRCUIT AND ULTRASOUND DIAGNOSTIC APPARATUS - An ultrasound transducer drive circuit includes an output line connected to an ultrasound transducer, a plurality of switching circuits each of which turns on and off a connection of a power supply unit with the output line, a plurality of ground clamp circuits each of which turns on and off a connection of the output line with ground, and a control signal output unit which outputs control signals for turning on and off the switching circuits and the ground clamp circuits. The switching circuits are different in impedance from one another, and the ground clamp circuits are different in impedance from one another. | 2010-12-30 |
20100331704 | INTEGRATED SENSOR FOR MEDICAL APPLICATIONS - A sensing assemblage ( | 2010-12-30 |
20100331705 | METHOD FOR DETECTING THE PRESENCE OF INHOMOGENEITIES IN AN INTERIOR OF A TURBID MEDIUM AND DEVICE FOR IMAGING THE INTERIOR OF TURBID MEDIA - A method for detecting the presence of inhomogeneities in an interior of a turbid medium ( | 2010-12-30 |
20100331706 | OPTICAL ANALYZER - An optical analyzer performing analysis excellent in spatial resolution and in invasion depth is provided. The analyzer includes a diagnostic light source section including a seed light source which outputs seed light, and a silica optical fiber to which seed light is input and which generates diagnostic light having a HE11 mode field pattern utilizing a nonlinear optical phenomenon, an irradiation optical system converging the diagnostic light and irradiating a measurement subject with the diagnostic light, an acquisition optical system acquiring object light generated at the measurement subject, a spectrum measurement section receiving the object light and measuring a frequency spectrum of the object light, a storage section storing information of a frequency spectrum of a known substance, and an arithmetic section calculating a correspondence between the frequency spectrum of the object light and the frequency spectrum of the known substance, and analyzing the measurement subject based on the calculation result. | 2010-12-30 |
20100331707 | BIOLOGICAL INFORMATION IMAGING APPARATUS, BIOLOGICAL INFORMATION ANALYZING METHOD, AND BIOLOGICAL INFORMATION IMAGING METHOD - A biological information imaging apparatus includes: a light source; an acoustic wave detector that detects an acoustic wave generated from a light absorption material in a living body that has absorbed a part of energy of light irradiated from the light source to the living body, and converts it into a first electric signal; a photodetector that detects optical intensity of a portion of the light irradiated from the light source to the living body and propagating in the living body, and converts it into a second electric signal; and a calculation unit that calculates optical property distribution information on the living body by making use of an analytical result of one of the first electric signal and the second electric signal for analysis of the other electric signal. | 2010-12-30 |
20100331708 | MONITORING CARDIOVASCULAR CONDITIONS USING SIGNAL TRANSIT TIMES - Methods for monitoring cardiovascular conditions, i.e., hyperdynamic circulation, vasodilation, vasoconstriction, or central-to-peripheral arterial pressure decoupling conditions are described. These methods involve measuring a central signal proportional to or a function of the subject's heart activity and a peripheral signal proportional to or a function of a signal related to the central signal. Then calculating a time difference between features in the central and peripheral signals representing the same heart event. The cardiovascular condition is indicated if the time difference is greater or lower than a threshold value, if the time difference is greater or lower than a threshold value over a specified period of time, or if there is a significant statistical change in the times over the specified time period. These methods can alert a user that a subject is experiencing the cardiovascular condition, which can enable a clinician to appropriately provide treatment to the subject. | 2010-12-30 |
20100331709 | DETECTION UNIT FOR BLOOD PRESSURE INFORMATION MEASUREMENT DEVICE AND BLOOD PRESSURE INFORMATION MEASUREMENT DEVICE - A blood pressure information measurement device includes a cuff ( | 2010-12-30 |
20100331710 | BLOOD PRESSURE MEASUREMENT CUFF THAT INCLUDES AN ANTIMICROBIAL SUBSTANCE - A blood pressure measurement cuff comprising an inflatable bladder, a source of fluidic pressure in fluidic communication with the inflatable bladder, a manometer in fluidic communication with the inflatable bladder, a cover at least partially covering the inflatable bladder and comprising an antimicrobial substance, and means to place the inflatable bladder sufficiently close to a limb of a living being to allow the measurement of the blood pressure of the living being. The source of fluidic pressure can be a pump that transforms human force into fluid pressure, such as a squeezable ball pump, or a canister of compressed fluid. The manometer can include a dial display or a digital display. The cuff can further comprise a tube providing fluidic communication between the manometer and the inflatable bladder, and the tube can be 1 foot or longer. The cover can be made of a fabric coated with an antimicrobial substance. | 2010-12-30 |
20100331711 | Method and device for deriving and evaluating cardiovascular information from curves of the cardiac current, in particular for applications in telemedicine - The invention relates to a method and a device for deriving and evaluating cardiovascular information from curves of the cardiac current, in particular for applications in telemedicine. According to the invention, for data reduction purposes, a mean value and a standard deviation across the whole recording time are initially determined from a recorded ECG from the high-resolution signal, after which the RR intervals are assessed by means of an identification algorithm and only the results obtained are transmitted and/or recorded, for the purpose of data reduction. | 2010-12-30 |
20100331712 | METHOD OF LOCATING THE TIP OF A CENTRAL VENOUS CATHETER - A method of locating a tip of a central venous catheter (“CVC”) having a distal and proximal pair of electrodes disposed within the superior vena cava, right atrium, and/or right ventricle. The method includes obtaining a distal and proximal electrical signal from the distal and proximal pair of electrodes and using those signals to generate a distal and proximal P wave, respectively. A deflection value is determined for each of the P waves. A ratio of the deflection values is then used to determine a location of the tip of the CVC. Optionally, the CVC may include a reference pair of electrodes disposed within the superior vena cava from which a reference deflection value may be obtained. A ratio of one of the other deflection values to the reference deflection value may be used to determine the location of the tip of the CVC. | 2010-12-30 |
20100331713 | POST-EXERCISE ARRHTYMIA DETECTION - Post-exercise arrhythmias are detected by an implantable medical device. In some aspects, post-exercise arrhythmia may be prognostic of a worsening cardiovascular condition. Thus, the detection of post-exercise arrhythmia may be used as an indicator for adjusting the therapy prescribed for a patient. In some aspects post-exercise arrhythmia are detected if a patient is exercising at a level that equals or exceeds a threshold exercise level. In some aspects, therapy for a patient is modified if the detected post-exercise arrhythmia exceeds a threshold arrhythmia level. In some aspects therapy for a patient is modified if ischemia is detected in conjunction with post-exercise arrhythmia. | 2010-12-30 |
20100331714 | HEART RATE MONITOR WITH CROSS TALK REDUCTION - A heart rate monitor determines a heart rate for a primary subject by reducing noise and cross-talk from unwanted signal transmission sources. A set of pulse peaks having about the same amplitude and an amplitude greater than any other set of peaks are processed to determine a subject's heart rate, while data having an amplitude below that of the set of peaks is ignored. To retrieve enough data to determine a peak amplitude, the signal having heart rate information is sampled at a frequency higher than a normal sampling frequency. In some embodiments, if no data is received for a set time period which is in or above the range, the threshold resets to zero under an assumption that the primary subject is no longer within transmitting range. | 2010-12-30 |
20100331715 | SYSTEMS AND METHODS FOR DETECTING EFFORT EVENTS - A method and system for detecting effort events is disclosed. Effort may be determined through feature analysis of the signal as transformed by a continuous wavelet transform, which may be compared against a reference effort measure to trigger an effort event flag that signals the onset and/or severity of an effort event. For example, a respiratory effort measure may be determined based at least in part on a wavelet transform of a photoplethysmograph (PP G) signal and features of the transformed signal. A respiratory reference effort measure may be based at least in part on past values of the respiratory effort measure, and a threshold test may be used to trigger an effort event flag, which may indicate a marked change in respiratory effort exerted by a patient. | 2010-12-30 |
20100331716 | METHODS AND APPARATUS FOR MEASURING RESPIRATORY FUNCTION USING AN EFFORT SIGNAL - Breathing effort of a patient, as determined (for example) from a photoplethysmograph (“PPG”) signal from the patient, can be used in conjunction with signals from a spirometer being used by the patient to provide additional information about various characteristics of the patient's breathing. For example, such additional information may include the relationship between the patient's breathing effort and breath volume. As another example, the additional information may include the relationship between the patient's breathing effort and rate of breath flow. Still other such additional information may be derived from various combinations of spirometer and PPG output signals. | 2010-12-30 |
20100331717 | Seizure Sensing and Detection Using an Implantable Device - A system and method for detecting and predicting neurological events with an implantable device uses a relatively low-power central processing unit in connection with signal processing circuitry to identify features (including half waves) and calculate window-based characteristics (including line lengths and areas under the curve of the waveform) in an electrographic signal received from a patient's brain. The features and window-based characteristics are combinable in various ways according to the invention to detect and predict neurological events in real time, enabling responsive action by the implantable device. | 2010-12-30 |
20100331718 | PROPAGATION TUNED OSCILLATOR FOR ORTHOPEDIC PARAMETER MEASUREMENT - A measurement system for capturing a transit time, phase, or frequency of energy waves propagating through a propagation medium ( | 2010-12-30 |
20100331719 | METHOD AND IMPLANTABLE MEDICAL DEVICE (IMD) FOR MONITORING PERMEABILITY STATUS OF CELL MEMBRANES - An implantable medical device comprises a signal generator for generating a current signal having a frequency in a frequency window slightly less than the β-dispersion frequency of a tissue and applying the signal over the tissue. A signal measurer measures the resulting voltage signal and an impedance parameter is calculated from the applied and measured signal by a parameter determiner. A status monitor monitors the permeability status of cell membranes in the tissue based on this impedance parameter. | 2010-12-30 |
20100331720 | Intravaginal device with wireless sensors of fertility indicators - A convenient and highly accurate intravaginal device with wireless sensors for monitoring fertility and sexual health of humans and animals is proposed. Sensors in the intravaginal device measure fertility and sexual health and via wireless transmitter send this information to a terminal on which the information is processed and displayed in convenient form. | 2010-12-30 |
20100331721 | Head-stabilized, nystagmus-based repositioning apparatus, system and methodology - Structure and methodology involving mountable and head-wearable frame structure which is positionally stabilized, during use, relative a human subject's head, and which carries a selection of positionally anchored data sensors, and stimuli deliverers, that are relevant to the diagnosis and treatment of vestibular disorders. Special configurations are provided for two types of stimulators, one for sound application and air-pressure modification, and the other for the introduction of fluids to the ear. Stabilization enables tight and accurate correlation of data which is quickly analyzable by a connected, properly algorithmed computer, which can also be used for feedback control in a designed “expert” system. The invention enables, among other things, practical and significant differentiation between physiological and pathological nystagmus. | 2010-12-30 |
20100331722 | Device and method for assessing operant facial pain - The subject invention concerns a method and device for assessing facial pain sensitivity exhibited by an animal. The device and method can be used, for example, to evaluate the effect of a disease state, drug, or other intervention, on facial pain sensitivity, such as orofacial pain sensitivity. In one embodiment, the device and method provide a way of assessing both heat and cold sensitivity (hyperalgesia and allodynia) in the facial region in a non-invasive manner. Additionally, since the animals can be kept unrestrained, there are less confounding factors such as stress, which are inherent to other facial pain testing techniques. | 2010-12-30 |
20100331723 | Two-Point Discriminator - The invention relates to a design for an instrument for measuring two-point discrimination between two blunt points. The instrument includes a housing, a first needle, a second needle, and a mechanism for providing movement to at least one of the needles. | 2010-12-30 |
20100331724 | DETERMINING A CHARACTERISTIC BLOOD PRESSURE - The present disclosure relates to monitoring a characteristic physiological parameter of a patient during a suitable time period that either precedes or follows a triggering event, such as a clinician/patient interaction, that may negatively impact the physiological parameter. In some embodiments, physiological parameter values falling between one or more pre-set thresholds may be used to derive the characteristic physiological parameter. In some embodiments, tracking the physiological parameter may provide additional information about the patient's status. In some embodiments, confidence measures may be associated with, or may be used to analyze features of the patient signal to derive information about, the characteristic physiological parameter. The patient signal used to derive a patient's physiological parameter may be of an oscillatory nature or may include oscillatory features that may be analyzed to derive a characteristic respiration rate. | 2010-12-30 |
20100331725 | APPARATUS FOR GENERATING AND COLLECTING SALIVA SAMPLES CONTAINING ENHANCED CELL CONCENTRATIONS - An apparatus for generating and collecting saliva samples containing enhanced cell concentrations includes a mouthpiece having a mouth contact portion and a flow channel which may include a tapered basin, a conduit in fluid communication with the flow channel, and one or more collectors couplable to the conduit. The mouth contact portion and basin may be textured to enhance cell removal. The mouth contact portion may include a plurality of internal and external channels disposed around the flow channel. Filters may be included between the flow channel and the collectors. A closure member is provided. | 2010-12-30 |
20100331726 | Medical Device with Incorporated Disinfecting Wipe and Method of Using Same - A medical device including a barrel having an open first end and capable of supporting a needle at a second end of the barrel is provided and includes a lid releasably adhered to and overlying the open first end of the barrel in a fluid tight manner; and a pad secured to a surface of the lid such that the pad is disposed within a cavity of the barrel when the lid is adhered to the barrel, wherein the pad comprises a disinfecting solution. | 2010-12-30 |
20100331727 | Linear Device for Microdialysis, Method of Manufacturing the Device and Method for Studying a Tissue with the Device - There is provided a linear device ( | 2010-12-30 |
20100331728 | INTEGRATED DEVICES HAVING EXTRUDED ELECTRODE STRUCTURES AND METHODS OF USING SAME - The present disclosure provides electrode structures and integrated electrode structures having one or more conductive materials coextruded with one or more dielectric materials. The disclosed electrode structures can be configured for use as analyte sensors. Also provided, are methods of making and using the electrode structures and integrated electrode structures described herein. | 2010-12-30 |
20100331729 | CIRCUIT BOARD FOR BODY FLUID COLLECTION, AND BIOSENSOR - A circuit board for body fluid collection include a first substrate including a puncture needle; a second substrate disposed at an upstream side of the first substrate in a direction of puncturing with the puncture needle with a space provided therebetween; a flexible insulation layer that extends between the first substrate and the second substrate; and a conductive pattern provided on the flexible insulation layer, the conductive pattern integrally including an electrode, a terminal, and a wiring that electrically connects the electrode and the terminal. | 2010-12-30 |
20100331730 | CIRCUIT BOARD FOR BODY FLUID COLLECTION, METHOD FOR PRODUCING THE SAME, METHOD FOR USING THE SAME, AND BIOSENSOR - A circuit board for body fluid collection includes a plurality of measurement units including a puncture needle and an electrode for making contact with a body fluid collected by puncturing with the puncture needle, the plurality of measurement units being arranged in parallel in a predetermined direction, and a support portion extending along the parallel arrangement direction and supporting the plurality of measurement units, wherein the support portion is rolled so that the plurality of measurement units can be disposed radially. | 2010-12-30 |
20100331731 | BLOOD AND INTERSTITIAL FLUID SAMPLING DEVICE - A device and method for lancing a patient, virtually simultaneously producing and collecting a small fluid sample from a body. The device comprises a blood collection system including a lancing needle, drive mechanism, kneading or vibration mechanism, optional suction system, and sample ejection mechanism. The device is preferably sized to be hand-held in one hand and operable with one hand. The device can optionally contain integral testing or analysis component for receiving the sample and providing testing or analysis indication or readout for the user. In one configuration, the lancing needle may be withdrawn very slightly from the point of maximum penetration to create an opening in which blood can pool before being suctioned through to device. | 2010-12-30 |
20100331732 | Guide Wire Advancer Assembly and Methods for Advancing a Guide Wire - A guide wire advancer ( | 2010-12-30 |
20100331733 | SENSING DEVICE AND METHOD FOR AN ORTHOPEDIC JOINT - One embodiment is directed to a sensor for measuring a skeletal system. A signal path of the system comprises an amplifier ( | 2010-12-30 |
20100331734 | SYSTEM AND METHOD FOR ORTHOPEDIC LOAD SENSING INSERT DEVICE - A sensing insert device ( | 2010-12-30 |
20100331735 | WIRELESS POWER MODULATION TELEMETRY FOR MEASURING A PARAMETER OF THE MUSCULAR-SKELETAL SYSTEM - A sensing insert device ( | 2010-12-30 |
20100331736 | WIRELESS SENSING MODULE FOR SENSING A PARAMETER OF THE MUSCULAR-SKELETAL SYSTEM - A sensing insert device ( | 2010-12-30 |
20100331737 | ENCAPSULATED FORCE SENSOR FOR MEASURING A PARAMETER OF THE MUSCULAR-SKELETAL SYSTEM - A sensing insert device ( | 2010-12-30 |
20100331738 | INTEGRATED SENSOR AND INTERCONNECT FOR MEASURING A PARAMETER OF THE MUSCULAR-SKELETAL SYSTEM - A sensing insert device ( | 2010-12-30 |
20100331739 | METHOD AND SYSTEM FOR PREDICTING CALVING - A method and a system for predicting a calving date of an animal comprises monitoring a behavioral pattern of an animal, determining a given change in the behavioral pattern, and predicting the calving date responsive to the given change in the behavioral pattern. | 2010-12-30 |
20100331740 | THROMBOSIS AND OSTEOPOROSIS PROPHYLAXIS - Use of a device to reduce risk of thrombosis and osteoporosis, which uses a pressure transducer to measure the forefoot force generated by a person with their forefoot, and generates a signal so that the person can recognize whether their forefoot force has reached a minimum value. | 2010-12-30 |
20100331741 | Medical treatment system including an ancillary medical treatment apparatus with an associated data storage medium - A medical treatment system includes an electronic controller with a medical treatment apparatus, a data reader, an ancillary treatment apparatus used with the electronic medical treatment apparatus and a data storage medium associated with the ancillary treatment apparatus. The controller is configured to receive information from the data storage medium, and to control the medical treatment apparatus with medical treatment parameters compatible with the desired medical treatment and the ancillary treatment apparatus. | 2010-12-30 |
20100331742 | SURGICAL OPERATING APPARATUS - A surgical operating apparatus includes a probe for outputting energy for performing therapeutic treatment of a living body, a jaw which is openable/closable relative to the probe, and an output mode switching section which selectively switches, in accordance with an open/closed state of the jaw, an output of the surgical operating apparatus between a bipolar mode in which the probe and the jaw are used as high-frequency electrodes, and a probe-only output mode in which the energy is output from only the probe. | 2010-12-30 |
20100331743 | APPARATUS AND METHOD FOR AN ULTRASONIC MEDICAL DEVICE OPERATING IN TORSIONAL AND TRANSVERSE MODES - The present invention provides an apparatus and a method for an ultrasonic medical device operating in a torsional mode and a transverse mode. An ultrasonic probe of the ultrasonic medical device is placed in communication with a biological material. An ultrasonic energy source is activated to produce an electrical signal that drives a transducer to produce a torsional vibration of the ultrasonic probe. The torsional vibration produces a component of force in a transverse direction relative to a longitudinal axis of the ultrasonic probe, thereby exciting a transverse vibration along the longitudinal axis causing the ultrasonic probe to undergo both a torsional vibration and a transverse vibration. The torsional vibration and the transverse vibration cause cavitation in a medium surrounding the ultrasonic probe to ablate the biological material. | 2010-12-30 |
20100331744 | Massager - Disclosed is an apparatus for massaging the body of a user comprising an arcuate member extending between first and second opposed ends and a central portion therebetween. The first and second ends are oriented away from the central portion and the arcuate member defines an arc having an angle of less than 180 degrees. The apparatus further comprises gripping portions disposed at the first and second opposed ends and a therapy applicator connectable to the central portion. | 2010-12-30 |
20100331745 | Reciprocating Tapping Device - A reciprocating tapping device includes a casing, a motor, a power supply, a transmission portion and a tapping portion. The tapping portion is connected with and driven by the transmission portion. An eccentric shaft is connected with the transmission portion. The tapping portion has a reciprocating portion. The reciprocating portion is connected with two tapping bars. The bars extend out of the casing. The eccentric shaft can covert the circular motion of the motor to back-and-forth motion. Therefore, the tapping portion can move backwards and forwards and the two tapping bars can move backwards and forwards. A flat plate is disposed in the front and back of the reciprocating portion so as to pivotally hold the reciprocating portion. Therefore, the tapping portion can move backwards and forwards without any sideway motion. | 2010-12-30 |
20100331746 | METHOD OF USING ENOXAPARIN FOR REDUCING THE RISK OF DEATH IN ACUTELY ILL MEDICAL PATIENTS - The invention relates to a method of using of enoxaparin for reducing the risk of death in acutely ill medical patients. | 2010-12-30 |
20100331747 | Protective cast cover for bathing - A cover is adapted to be worn over a user's limb to shield a bandage, dressing or cast from exposure to water. The cover includes a generally elongate body defined by a shell formed of a flexible, water resistant and air breathing material. The shell surrounds an interior of the cover, including a lower interior chamber and an upper interior chamber. An open top end communicates with the upper interior chamber and is sized and configured to permit passage of the user's limb and the cast, bandage or dressing therethrough and into the upper and lower interior chambers. A cinch strap with a releasable securing mechanism closes the open top end snug around the user's limb to provide a first barrier against water entry into the interior. An inner cuff separates the upper and lower interior chambers and includes an elastomeric opening that fits snug against the user's limb, above the cast, bandage or dressing, to provide a second barrier against water entry into the lower interior chamber. | 2010-12-30 |
20100331748 | DONNING POTENTIATING SUPPORT WITH EXPANDABLE FRAMEWORK FASTENED TO GARMENT - A method of donning a potentiating support for a hinge joint of a body includes positioning a garment proximate an area of a body; positioning an expandable and recoverable framework in abutment with the area of the body such that the framework spans a hinge joint of the body, the framework defining a plurality of permanent openings extending therethrough regardless of whether the support is donned; applying tension at points of the framework such that the framework is expanded and the framework is tensioned in its abutment with the area of the body, said step of applying tension being performed by pulling on one or more fastening components that are attached at one or more points to said framework; and affixing each of the fastening components to the garment while applying tension to the framework to secure the expanded framework in its forced abutment with the area of the body. | 2010-12-30 |
20100331749 | ORTHOTIC HEEL SUPPORT DEVICE - This invention provides an orthotic sock comprising a tubular main body having two ends, one of which may be sized to snugly fit over the wearer's ankle while the second end may be sized to snugly fit over at least a portion of the wearer's foot, an orthotic heel lift and an internal pocket, located within the main body, that substantially encloses a heel lift whereby the lift is held in place against the wearer's heel by the sock. | 2010-12-30 |
20100331750 | ORTHOPEDIC DEVICE - An orthopedic device has a rigid or semi-rigid frame element defining opposed first and second sides, and is adapted to extend about at least a portion of a limb. The device includes straps formed from a variety of segments having stretchable and substantially inelastic segments. The straps adjustably secure to the frame element, and stretch relative thereto. The device also includes a central strap pad arranged to connect two straps together such that a first strap of the two straps is movable relative to a second strap, and the first and second straps are maintained diagonal relative to one another. | 2010-12-30 |
20100331751 | Burn Glove and Sock - An improved burn glove and sock is presented comprised of non-biological materials produced with a series of regularly-spaced pores and uniform three dimensional nylon structure/weave netting. Incorporated into the silicone/nylon weave structure are collagen peptides and other biological and non-biological agents selected for their therapeutic effect on burn wounds. | 2010-12-30 |
20100331752 | Helmet trauma bandage and method - An emergency helmet trauma bandage and method of use, which, when applied, applies minimal pressure to stop bleeding, doesn't compromise cervical spine immobilization, allows for fast and effective application of ice/cold packs to control intracranial/internal swelling, doesn't come apart during treatment and transport, and doesn't require a caregiver to re-wrap the dressing. | 2010-12-30 |
20100331753 | A Blood Purification Method and Apparatus for the Treatment of Malaria - Methods for treating malaria are provided, the treatment comprising the step of removing malaria-infected red blood cells from the patient s blood. Blood is drawn from the patient s circulatory system and circulated through a blood purification device that selectively eliminates the infected red blood cells from all other blood s components and replaces the cleansed blood back into the patient s circulatory system. A blood purification device, which is useful to perform the therapeutic methods of the invention, is also provided. The device leverages the magnetic properties of the hemozoin contained within the infected red blood cells and comprises one or more separation chambers ( | 2010-12-30 |
20100331754 | Method and Systems for Controlling Ultrafiltration Using Central Venous Pressure Measurements - The volume of fluid removed from a patient during ultrafiltration is controlled automatically on the basis of central venous pressure (CVP) measurements. In one embodiment, a central venous catheter (CVC) is used for accessing blood during dialysis. A sensor located at the tip of the catheter or inside the dialysis machine is used to periodically measure CVP. CVP feedback data helps prevent the excessive removal of fluids from the patient. | 2010-12-30 |
20100331755 | METHODS FOR SELECTIVE THERMAL TREATMENT - Systems and methods for selective cooling of a target site include a catheter having a supply lumen and a delivery lumen, with inlet and exit ports. Blood is withdrawn from the supply lumen and cooled or heated in a control unit. The treated blood is sent to the targeted area via delivery lumen. The supply lumen can act as an insulator for the delivery lumen. | 2010-12-30 |
20100331756 | Methods and Apparatus for Anchoring within the Gastrointestinal Tract - The present invention relates to an anchor configured for minimally-invasive implantation and sized to remain securely positioned within at least a portion of the gastrointestinal tract of an animal. The anchor includes a radial spring formed from an elongated resilient member shaped into an annular wave pattern about a central axis. The anchor defines a central lumen and provides an outward radial force, while allowing for substantial flexure about its perimeter. The anchor is generally removable, but can include fasteners, such as barbs, to further secure it to the surrounding anatomy. In some embodiments, the anchor includes a connector coupling a fixed portion to a removable portion. Further, the anchor can be used to secure a medical device within the body, such as a flexible sleeve within the intestine. | 2010-12-30 |
20100331757 | DIALYSIS VALVE AND METHOD - A dialysis valve includes a tube attached between an artery and a vein which, when elongated, simultaneously narrows in diameter at at least one location. The narrowed portion of the tube decreases the volume and velocity between the arterial and venous side of the patient to prevent damage or intimal hyperplasia on the venous side between dialysis treatments. When the valve is opened for dialysis, an unrestricted blood flow exists between the arterial and venous side, permitting a controlled, open blood flow during dialysis. | 2010-12-30 |
20100331758 | IRREVERSIBLE ELECTROPORATION USING NANOPARTICLES - The present invention provides methods, devices, and systems for in vivo treatment of cell proliferative disorders. The invention can be used to treat solid tumors, such as brain tumors. The methods rely on non-thermal irreversible electroporation (IRE) to cause cell death in treated tumors. In embodiments, the methods comprise the use of high aspect ratio nanoparticles with or without modified surface chemistry. | 2010-12-30 |
20100331759 | CORROSION RESISTANT ELECTRODES FOR IONTOPHORETIC TRANSDERMAL DELIVERY DEVICES AND METHODS OF USE - Embodiments of the invention provide electrode assemblies and associated methods for the iontophoretic transdermal delivery of therapeutic agents. Many embodiments provide a corrosion resistant electrode for the iontophoretic transdermal delivery of various therapeutic agents. Such embodiments allow for the iontophoretic transdermal delivery of therapeutic agents such as iron compounds for prolonged periods without any substantial corrosion of the electrode, impedance increases or discoloration or irritation of the skin. Embodiments of the invention are particularly useful for the long term treatment of various chronic medical conditions such as iron deficient anemia. | 2010-12-30 |
20100331760 | BIODEGRADABLE IMPLANT FOR TREATING OR PREVENTING REPERFUSION INJURY - A biodegradable implant for iontophoretic therapeutic agent delivery is provided. The implant comprises a biodegradable battery and at least one biodegradable iontophoresis electrode assembly. The biodegradable battery comprises first and second biodegradable electrodes and a biodegradable polymer electrolyte layer between the first and second biodegradable electrodes. The biodegradable iontophoresis electrode assembly comprises a biodegradable iontophoresis electrode and a charged therapeutic agent. When the biodegradable battery is electrically connected to generate an electric current through the biodegradable iontophoresis electrode assembly, the charged therapeutic agent is delivered by iontophoresis to a target location. The charged therapeutic agent may be a scavenger for reactive oxygen species. The electrical connection of the biodegradable battery may be controlled remotely. | 2010-12-30 |
20100331761 | Apparatus and Method for Dermatological Wound Healing - A method is provided for treating a dermatological wound. A first step of the method includes providing an iontophoretic apparatus. The iontophoretic apparatus includes at least one surface for contacting a surface of the dermatological wound, a current source electrically coupled to the apparatus, a suction mechanism operably coupled to the apparatus, and a source of therapeutic molecules. A second step of the method includes placing the at least one surface of the iontophoretic apparatus into contact with at least a portion of the dermatological wound surface. A third step of the method includes activating the current source so that a plurality of therapeutic molecules is delivered to the dermatological wound. A fourth step of the method includes activating the suction mechanism to remove fluid and/or debris from the dermatological wound. The second, third, and fourth steps of the method are repeated until the dermatological wound is sufficiently healed. | 2010-12-30 |
20100331762 | Refillable Reservoir Lead Systems - Medical electrical lead systems and related methods are described. The medical electrical lead systems may be configured to be at least partially implanted in a body of a subject. Some variations of the medical electrical lead systems may comprise a lead body comprising a proximal end and a distal end and a lumen extending at least partially therebetween, at least one electrode in the proximity of the distal end of the lead body, and a reservoir in fluid communication with the lumen, where the reservoir is located at a position removed from the distal end of the lead body. Certain variations of the medical electrical lead systems may comprise a lead body comprising a proximal end and a distal end and first and second lumens extending at least partially therebetween, and at least one electrode in the proximity of the distal end of the lead body. | 2010-12-30 |
20100331763 | ULTRASOUND CATHETER WITH EMBEDDED CONDUCTORS - An ultrasound catheter comprises an elongate tubular body is disclosed. The elongate tubular body has a proximal region and a distal region opposite the proximal region. The tubular body defines a central lumen having a central lumen surface that is electrically conductive. The ultrasound catheter further comprises an elongate, hollow inner core extending through the central lumen and has an inner core outer surface that is electrically conductive. The ultrasound catheter further comprises an ultrasound radiating member positioned within the distal region of the tubular body and between the tubular body and the inner core, such that the tubular body conductive surface and the inner core conductive surface are both in electrical contact with the ultrasound radiating member. The ultrasound catheter further comprises an insulating sleeve positioned between the tubular body and the inner core in a region proximal to the ultrasound radiating member. | 2010-12-30 |
20100331764 | Controlling A Phacoemulsification Surgical System By Transitioning Between Pulse and Burst Modes - Methods of manipulating pulses of ultrasonic energy for use with an ophthalmic surgical device. | 2010-12-30 |
20100331765 | Unit Dose Drug Delivery Platform - The delivery systems of the present disclosure are configurable to administer either single-dose or multiple-doses of one or more substances to a user, for example to the eye, nose, mouth, ear or rectum of the user. The precise and repeatable dosing features of the presently disclosed delivery systems overcome many of the disadvantages associated with known methods for dispensing substances to, for example, the eye of a user. The delivery systems administer precise doses of a substance to a precise location from unit dosage forms that may be single-dose or multiple-dose unit dosage forms, which may be externally or internally pierced. | 2010-12-30 |
20100331766 | APPLICATOR - An applicator insertable into a living body includes a nozzle having an elongated nozzle main body and a nozzle head on a front end side of the nozzle main body and through which liquid together with gas is expelled, with the nozzle main body including a flexible curved section. The applicator also includes an outer tube in which is positioned a portion of the nozzle main body so as to be movable along a longitudinal direction. The angle or degree of curvature of the curved section is changed by inserting the curved section into the outer tube to thereby adjust the direction of the nozzle head relative to the axis of the nozzle main body. In addition, a longitudinally extending gap exists between the outer tube and the nozzle. The gap functions as a discharge path for discharging the gas within the body cavity. | 2010-12-30 |
20100331767 | INTRACORPOREAL GAS EXCHANGE DEVICES, SYSTEMS AND METHODS - A system for intracorporeal gas exchange includes a flexible, rotatable shaft; a plurality of axially spaced agitation mechanisms positioned on the rotatable shaft, such that the rotatable shaft can flex between the axially spaced agitation mechanisms; a plurality of hollow gas permeable fibers adapted to permit diffusion of gas between intracorporeal fluid and an interior of the hollow fibers. The plurality of hollow fibers is positioned radially outward from the agitation mechanisms. A blood contacting medical system includes at least one seal, and a purge system via which a flushing fluid is introduced under pressure over a blood-side face of the seal and caused to flow through a space on the blood side of the seal. The system can further include a rotatable member. The space on the blood side of the seal can be in fluid connection with an annular space adjacent to a rotating element operatively connected to the rotatable member. | 2010-12-30 |
20100331768 | METHOD FOR CHECKING AND/OR MONITORING THE TIGHTNESS OF A PLURALITY OF PNEUMATICALLY OR HYDRAULICALLY ACTUATED ACTUATORS, AND MACHINE, ESPECIALLY MEDICAL TREATMENT MACHINE - The present invention relates to a method for checking and/or monitoring the leak tightness of a plurality of pneumatically or hydraulically actuated actuators of a machine, in particular a plurality of valve actuators of a medical treatment machine, wherein pressure is exerted on the actuators in different combinations during the operation of the machine, wherein the common pressure drop occurring during a stationary operating phase at the actuators on which pressure is exerted in the respective combination is measured for a plurality of different combinations of actuators on which pressure is exerted, and wherein a respective leak tightness value is determined for individual actuators and/or groups of actuators with the pressure drop which is measured for those combinations and in which the respective actuator and/or the respective group of actuators on which pressure is exerted being taken into said leak tightness value. The invention furthermore includes a machine, in particular a medical treatment machine, having a corresponding valve actuator monitoring. | 2010-12-30 |
20100331769 | NOZZLE FOR HIGH-SPEED JETTING DEVICES - A nozzle for jetting devices is described comprising e.g. one patterned silicon substrate enabling semiconductor mass production. The method of manufacturing the nozzle is characterized by using one mask layer deposited on the silicon substrate. The etching of the silicon substrate is done by means of a first isotropic etching step and a second anisotropic etching step through the mask layer, resulting in a perfectly aligned nozzle. | 2010-12-30 |
20100331770 | Implantable Drug Delivery Devices and Methods of Making the Same - A drug delivery device is provided that includes a device body, a number of solid, compressed drug tablets, and a retention frame. The device body includes a drug reservoir lumen and a retention frame lumen. The number of solid, compressed drug tablets are positioned in the drug reservoir lumen, and the retention frame is positioned in the retention frame lumen. The drug tablets may be mini-tablets aligned in the drug reservoir lumen, with an interstice formed between any two adjacent drug tablets facilitating deformation of the device body. Systems and method are also provided for loading a drug delivery device. In one embodiment, the method includes positioning one or more solid drug units upstream of the drug delivery device; and driving the drug units into the drug delivery device with a flow of pressurized gas. | 2010-12-30 |
20100331771 | INTEGRATED DEVICES HAVING EXTRUDED ELECTRODE STRUCTURES AND METHODS OF USING SAME - The present disclosure provides electrode structures and integrated electrode structures having one or more conductive materials coextruded with one or more dielectric materials. The disclosed electrode structures can be configured for use as analyte sensors. Also provided, are methods of making and using the electrode structures and integrated electrode structures described herein. | 2010-12-30 |
20100331772 | DRUG-TRANSFER DEVICE, DRUG-DELIVERY SYSTEM INCORPORATING THE SAME, METHODS OF FABRICATING THE SAME, AND METHODS OF ENABLING ADMINISTRATION OF A DRUG - Devices capable of deterring or preventing bulk extraction of drugs from, for example, drug-delivery systems are exemplarily disclosed. In one embodiment, such a device may include a package releasably retaining a drug and an agent. The agent is configured to suppress a physiological effect of the drug when the agent contacts the drug or is coadministered with the drug. The cell package is configured such that an amount of the drug is selectively releasable with respect to the agent when the package is operably proximate to an encoded key. The package, however, may be configured to impose a relatively high likelihood that either the drug will not be accessed or the drug will be contaminated by the agent if access to the contents of the package is sought without the use of an encoded key. | 2010-12-30 |
20100331773 | MEDICAL MIXING DEVICE - A drug storage and delivery device ( | 2010-12-30 |
20100331774 | STERILE APPLIANCE DELIVERY DEVICE FOR ENDOSCOPIC PROCEDURES - A surgical device comprising a container and a tether used for delivering a sterile appliance into a body cavity during endoscopic procedures. Once positioned in the body cavity, a force is applied to the container through the tether. The force opens the container and releases the sterile appliance into the body cavity. In various embodiments, gas or liquid may be used to open the container. | 2010-12-30 |