52nd week of 2012 patent applcation highlights part 51 |
Patent application number | Title | Published |
20120329619 | Fitness Board - An exercise or fitness board having a deck adjustably attached to a base to adjust the angle of incline of the deck relative to the base, and a plurality of straps attached to the deck for the user to grasp for balance and exercise. The deck and/or base contains various contours, scallops, cutouts, and the like to facilitate comfortable and varied positioning of the body. A rail and/or channel may be placed on the underside and along the perimeter of the board to facilitate grip. A pad or mat may be placed on top of the board and/or base for comfort, stability, and protection. | 2012-12-27 |
20120329620 | EXERCISE APPARATUS - The present invention comprises an adjustable exercise apparatus safe and effective for full body weight exercises, movements, stretches, and training. The present invention comprises a system for holistic body weight training such as yoga, martial arts, stretching, physical therapy, rehabilitation, and physical exercise training. The exercise apparatus comprises linking elements comprising elongated connectors, closed connectors, and openable connectors. The adjustable exercise apparatus comprises at least a dual anchor system which enables a user to safely exercise without impinging the apparatus' linking elements which are parallel to the user's sagittal plane. | 2012-12-27 |
20120329621 | Foot, leg, and arm support for exercise - A foot/leg/arm rest that is fully height and width adjustable. In addition, support cups can be positioned over a wide range of fixed angles to accommodate any user. The supports have a wide base that provides strong, firm and stable support for the device when it is used. The invention has two horizontal end members and a central connecting track. Two vertical post supports are positioned in the track and are slidably installed so that they can be positioned at any desired location within the track. In fact, one of the posts can be removed if desired so that only one post is in use. Each post is height adjustable independent of the other. This allows that supports to be positioned at two different levels, if desired. Each post has a support secured to it using a bracket that can be set to a wide range of angles. | 2012-12-27 |
20120329622 | Rehabilitation Exercising Equipment that can Extend a User's Arms - A rehabilitation exercising equipment includes a main frame, a first geared member rotatably mounted on the main frame, a second geared member rotatably mounted on the main frame, a connecting mechanism mounted between the first geared member and the second geared member to connect the first geared member and the second geared member so that the first geared member and the second geared member are movable in concert with each other, and two handlebars secured on the first geared member and the second geared member to rotate in concert with the first geared member and the second geared member respectively. Thus, a user's two hands can hold the handlebars to pivot the two handlebars in two opposite directions by connection of the connecting mechanism so as to achieve an exercising or rehabilitating function. | 2012-12-27 |
20120329623 | STRETCH ASSIST BLOCK - A stretch assist aid for safely and incrementally increasing a user's flexibility while objectively measuring the user's progress. | 2012-12-27 |
20120329624 | Rehabilitation Exercising Equipment that can Extend a User's Arms and Legs - A rehabilitation exercising equipment includes a main frame, a seat unit mounted on the main frame, and two swinging mechanism each pivotally mounted on the main frame. Thus, when the two swinging mechanism are driven by the user's arms or legs, the two swinging mechanism are pivoted relative to the main frame and are moved outward and inward in a reciprocal manner to exercise or rehabilitate the user's arms and legs so as to achieve an exercising or rehabilitating function. | 2012-12-27 |
20120329625 | METHOD OF FABRICATING A SELF-RIGHTING CORE FITNESS BALL AND CORE FITNESS BALL - A core fitness ball includes an inflatable ball and a metal bung within the interior of the ball. The ball further includes a target on an outer surface thereof which designates body positioning information for the user. | 2012-12-27 |
20120329626 | ASSISTED CHIN/DIP EXERCISE APPARATUS WITH ADJUSTABLE CHIN-UP/PULL-UP HANDLES - An assisted chin/dip exercise apparatus has a main frame and an assist or foot bar pivotally mounted on the frame and linked to a weight stack or resistance for assisting a user standing on the foot bar during performance of chin and dip exercises. The main frame has a first, overhead handle assembly and a second, dip handle assembly below the first handle assembly. The first handle assembly includes a pair of adjustably mounted handles freely pivotable between a first, chin-up position in which the handles extend towards one another at a rearward angle with a small spacing between the handles and a second, pull-up position in which the handles extend in a forward direction and are spaced apart by a larger spacing sufficient to provide head clearance for a user stepping onto the foot bar or while performing a dip exercise. | 2012-12-27 |
20120329627 | SYSTEMS AND METHODS FOR CREATING A MANUFACTURER'S JOINT AND CLOSING A BOX - A system is disclosed for sealing a manufacturer's joint and/or the ends of a customized box. The system includes at least a first arm spaced apart from a second arm. The arms are arranged so that an end flap of a box blank can be inserted between the arms to align the box blank relative to the arms and secure and maintain at least two side panels of the box blank in an adjacent position to form a manufacturer's joint. Methods for forming and sealing a manufacturer's joint and/or the ends of a customized box are also disclosed. Such methods, are designed to, for example, reliably form, close, and seal the manufacturer's joint and/or the ends of a customized box in a simplified manner. | 2012-12-27 |
20120329628 | FOLDING APPARATUS FOR FOLDING OF NON-RIGID MATERIAL PARTS - A folding apparatus for folding of non-rigid material parts has a folding unit for folding of individual non-rigid material parts, a storage unit for receiving the folded non-rigid material parts from the folding unit, a supply unit for keeping non-folded non-rigid material parts on hand, and a transport unit for feeding the non-folded non-rigid material parts from the supply unit to the folding unit, and a provisioning unit keeping set items on hand for the folding unit. The provisioning unit has a withdrawal unit for storage of unsorted set items and a deposit unit for receiving sorted set items. | 2012-12-27 |
20120329629 | FLEXIBLE DUNNAGE HANDLER - A dunnage accumulator includes a first holding portion ( | 2012-12-27 |
20120329630 | SCREEN CLAMP WITH INTEGRATED CENTER FEED - A screen clamp with integrated center feed is disclosed. The screen clamp may be rotatably mounted in a continuous centrifuge. The screen clamp may comprise: a feed cone having a base and sidewall, wherein a center of the base has a feed opening and the sidewall has one or more discharge openings; and an outer flange attached to and extending along a bottom edge of the feed cone, wherein the outer flange is configured to secure a basket filtering screen of a continuous centrifuge to a basket. The screen clamp may be configured to direct a massecuite feed entering the feed opening through the one or more discharge openings and onto the basket filtering screen. The screen clamp may also comprise a weir. | 2012-12-27 |
20120329631 | SCREEN BOWL CENTRIFUGE AND METHOD - A screen bowl centrifuge having first and second conically diverging screen sections. And a method of separating solids from liquid of a slurry includes feeding a slurry from a conveyor hub to a cylindrical section of a bowl extending about the conveyor hub; scrolling the solids along the cylindrical section in a first direction and a majority of the liquid in a second direction opposite the first direction using at least one helical blade extending from the conveyor hub; and sliding the solids from the cylindrical section along a conically diverging screen section of the bowl that includes a first conically diverging section and a second conically diverging section, the first conically diverging section extending at a first angle to the axis and the second conically diverging section extends at a second angle to the axis, and the first angle is different from the second angle. | 2012-12-27 |
20120329632 | Composite Compacts Formed of Ceramics and Low Volume Cubic Boron Nitride and Method of Manufacture - A composite compact formed by sintering, at high temperature/high pressure, a composition including cBN in a range of about 5 to about 60 vol. %, zirconia (or in the range about 5 to about 20 vol. %), and other ceramic material. Subsequent to sintering, the zirconia exists in the cubic phase and/or tetragonal phase. The zirconia may be either stabilized or unstabilized prior to sintering. The other ceramic material may include one or more of nitrides, borides, and carbides of Ti, Zr, Hf, Al, Si, or Al | 2012-12-27 |
20120329633 | CERAMIC SINTERED BODY AND METHOD FOR PRODUCING CERAMIC SINTERED BODY - Provided is a mono- or multilayer ceramic substrate which exhibits a high flexural strength. The substrate contains a sintered ceramic which includes respective crystal phases of quartz, alumina, fresnoite, sanbornite, and celsian, in which the relationship between the diffraction peak intensity A in the (201) plane of the fresnoite and the diffraction peak intensity B in the (110) plane of the quartz, measured by a powder X-ray diffractometry in the range of the diffraction peak angle 2θ=10 to 40°, is A/B≧2.5. The fresnoite crystal phase preferably has an average crystal grain size of 5 μm or less. In firing to obtain this ceramic sintered body, the maximum temperature falls within the range of 980 to 1000° C. | 2012-12-27 |
20120329634 | COLUMNAR ALUMINUM TITANATE AND METHOD FOR PRODUCING SAME - Provided are aluminum titanate capable of providing a sintered body having a low coefficient of thermal expansion, a high porosity, and high mechanical strength, a production method of the same, and a sintered body of the columnar aluminum titanate. The columnar aluminum titanate has an average aspect ratio (=(number average major-axis length)/(number average minor-axis length)) of 1.5 or more and its magnesium content is preferably within the range of 0.5% to 2.0% by weight relative to the total amount of titanium and aluminum in terms of their respective oxides. | 2012-12-27 |
20120329635 | NOVEL ENHANCED HIGH Q MATERIAL COMPOSITIONS AND METHODS OF PREPARING SAME - A framework for developing high quality factor (Q) material for electronic applications in the radio frequency range is provided. In one implementation, ceramic materials having a tungsten bronze crystal structure is modified by substituting one or more elements at one or more lattice sites on the crystal structure. The substitute elements are selected based on the ionic radius and other factors. In other implementations, the modified ceramic material is prepared in combination with compositions such as rutile or a perovskite to form a orthorhombic hybrid of perovskite and tetragonal tungsten bronze. | 2012-12-27 |
20120329636 | BELT-SHAPED METAL NANOSTRUCTURE AND METHOD FOR PREPARING SAME - The present invention relates to a belt-shaped metal nanostructure in which a wide surface area of catalytically active material can be realized even by a relatively small amount thereof so that it shows an excellent catalytic activity, and a method for preparing same. | 2012-12-27 |
20120329637 | CLOTH-LIKE RADIOACTIVE MATERIAL ADSORBENT AND ITS MANUFACTURING METHOD - A renewable adsorbent enabling to adsorb cesium selectively and efficiently, and to reuse cesium by eluting adsorbed cesium, and its manufacturing method are provided. Polyethylene (PE)/polypropylene (PP) based non-woven fabric may be exposed with electron beam, PE/PP based non-woven fabric to which electron beam was exposed is contacted to the monomer solution containing acrylonitrile (AN), dimethyl sulfoxide (DMSO), Tween80 (polyoxyethylene sorbitan monooleate) as a surfactant, and AMP (ammonium molybdophosphate n-hydrate) as an inorganic ion exchanger, and then the inorganic ion exchanger (AMP) is supported directly by the non-ionic graft chain. | 2012-12-27 |
20120329638 | Method For Manufacturing Catalyst From Recovered Catalyst - The present invention relates to a method for manufacturing a regenerated catalyst from a recovered catalyst from manufacturing process or a used catalyst of a heteropoly acid-based catalyst containing molybdenum, phosphorus, vanadium or copper as an essential component by the below-described Process a to Process f:
| 2012-12-27 |
20120329639 | PROCESS FOR MAKING IMPROVED CATALYSTS FROM CLAY-DERIVED ZEOLITES - This invention relates to a process of preparing an improved catalyst comprising a clay derived zeolite. In particular, the invention comprises combining an yttrium compound with a zeolite produced by treating clay with a silica source and under alkaline conditions. The clay derived zeolite can be further combined with conventional matrix and/or binder precursors to form particulates suitable for use as catalysts in fluid catalytic cracking (FCC). Alternatively, the clay that is treated with the silica source and alkaline conditions can be in particulate form having sizes suitable for use in FCC, and the zeolite is produced in situ within the particulate. Yttrium compound is then combined with the zeolite in the particulate, e.g., via impregnation. It has been shown that the addition of the yttrium compound improves zeolite surface area retention, and zeolite stability in catalysts comprising clay derived zeolites. | 2012-12-27 |
20120329640 | NANOPLATE-NANOTUBE COMPOSITES, METHODS FOR PRODUCTION THEREOF AND PRODUCTS OBTAINED THEREFROM - Compositions and methods of producing discrete nanotubes and nanoplates and a method for their production. The discrete nanotube/nanoplate compositions are useful in fabricated articles to provide superior mechanical and electrical performance. They are also useful as catalysts and catalyst supports for chemical reactions. | 2012-12-27 |
20120329641 | CATALYSTS FOR PRODUCING BROAD MOLECULAR WEIGHT DISTRIBUTION POLYOLEFINS IN THE ABSENCE OF ADDED HYDROGEN - The present invention provides a polymerization process utilizing a dual metallocene catalyst system for the production of broad or bimodal molecular weight distribution polymers, generally, in the absence of added hydrogen. Polymers produced from the polymerization process are also provided, and these polymers can have a Mn in a range from about 9,000 to about 30,000 g/mol, and a short chain branch content that decreases as molecular weight increases. | 2012-12-27 |
20120329642 | PLATINUM-PALLADIUM CATALYST WITH INTERMEDIATE LAYER - A fuel cell catalyst comprises a support having a core arranged on the support. In one example, the core includes palladium nanoparticles. A layer, which is gold in one example, is arranged on the core. A platinum overlayer is arranged on the gold layer. The intermediate gold layer greatly increases the mass activity of the platinum compared to catalysts in which platinum is deposited directly onto the palladium without any intermediate gold layer. | 2012-12-27 |
20120329643 | NOBLE METAL FINE PARTICLE SUPPORTED CATALYST AND METHOD FOR PRODUCING THE CATALYST, AND PURIFYING CATALYST - The noble metal fine particle supported catalyst of the present invention includes a substrate, and a porous membrane formed on the substrate. The porous membrane contains support particles, noble metal fine particles, and an inorganic binder. In the porous membrane, the noble metal fine particles are supported on surfaces of the support particles, and the support particles form secondary particles each having a porous structure. The porous membrane is formed by binding, with the inorganic binder, the secondary particles formed of the support particles so that a gap is present at least partly between the secondary particles adjacent to each other. | 2012-12-27 |
20120329644 | CATALYST COMPOSITION AND CATALYTIC REDUCTION SYSTEM - A catalyst composition, a method of preparation of catalyst composition, a catalytic reduction system including the catalyst composition and a system using the catalytic reduction system are provided. The catalyst composition includes a templated amorphous metal oxide substrate, a catalyst material, and a sulfur scavenger material. The catalyst material includes a catalyst metal disposed on the templated metal oxide substrate and the sulfur scavenger includes an alkali metal. | 2012-12-27 |
20120329645 | REFORMING CATALYST - Process for the steam reforming of hydrocarbons comprising contacting a feed gas with a catalyst consisting of an active compound in the form of an alloy of nickel and one of iridium, rhodium and ruthenium, on a support comprising alumina, zirconia, magnesia, titania, or combinations thereof. | 2012-12-27 |
20120329646 | THERMAL RECORDING MATERIAL AND METHOD FOR PRODUCING THE SAME - Provided is a thermal recording material comprising a heat-sensitive recording layer for color formation by heat and a protective layer stacked in this order on a support, the protective layer at least containing an acetoacetyl-modified polyvinyl alcohol crosslinked by a glyoxylate and an epichlorohydrin resin. | 2012-12-27 |
20120329647 | METHOD FOR ACTIVATING COLORANT ASSOCIATED WITH AN ARTICLE - Methods and apparatuses for activating colorant in selected regions of an article in which the colorant is incorporated are described. The colorant activation can create various desired visual aspects. | 2012-12-27 |
20120329648 | METHODS FOR GENERATING HIGH ASPECT-RATIO POLYMERIC PARTICLES COMPRISING AN ACTIVE INGREDIENT - The present invention relates to methods for generating polymeric particles which comprise one or more active ingredients. The invention also relates to the use of such polymeric particles as a seed treatment. The present technology provides an improved seed treatment suitable for applying plant propagation materials. The seed treatment of the present technology includes the use of high aspect-ratio particles as a seed treatment. The present technology has been found to have advantageous properties associated with the seed treatment including increased adherence of the formulation to the seed and reduced tendency to dust off. | 2012-12-27 |
20120329649 | PESTICIDAL COMPOSITIONS AND PROCESSES RELATED THERETO - This document discloses molecules having the following formula (“Formula One”): | 2012-12-27 |
20120329650 | Agricultural Uses of HYTd - Disclosed are compositions comprising chitosan, glucosamine and amino acids, where the concentration of chitosan is greater than 1.5 wt % and glucosamine is greater than 1.5 wt %. In preferred embodiments the concentration of chitosan is from 2 to 2.5 wt % and glucosamine is 2 to 6 wt %. The composition can also include solid chitin, but generally no more than about 2 wt %. The composition is generally a liquid but may be a solid. In most embodiments, the solid can be reconstituted with water prior to use. In preferred embodiments, the composition comprises HYTd and at least one of, HYTa, HYTb and HYTc. In still other embodiments the composition comprises HYTd and two or more of, HYTa, HYTb and HYTc. The composition can also comprise HYTd, HYTa, HYTb and HYTc. In the disclosed processes soil, seed, seedling or plant foliage are contacted with HYTd or any of the above compositions. | 2012-12-27 |
20120329651 | HERBICIDE EMULSIFIABLE CONCENTRATES WITH BUILT-IN ADJUVANT - Provided herein are herbicide emulsifiable concentrates containing a non-petroleum derived built-in adjuvant. | 2012-12-27 |
20120329652 | HERBICIDAL COMPOSITION AND METHOD OF USE THEREOF - The present invention relates to a to a method of controlling the growth of weeds, in particular, large crabgrass and white clover, using a herbicidal composition comprising mesotrione and a triazolinone herbicide such as sulfentrazone or carfentrazone-ethyl. The invention also relates to the use of this composition. | 2012-12-27 |
20120329653 | SYNERGISTIC HERBICIDAL COMPOSITION CONTAINING PENOXSULAM AND PENDIMETHALIN - A synergistic herbicidal composition containing (a) penoxsulam and (b) pendimethalin provides improved pre-emergence to early post-emergence herbicidal weed control of undesirable vegetation in multiple crops, including rice, cereal and grain crops, turf, IVM, sugar cane and tree and vine orchards. | 2012-12-27 |
20120329654 | CORN EVENT PV-ZMGT32(NK603) AND COMPOSITIONS AND METHODS FOR DETECTION THEREOF - The present invention provides a DNA construct that confers tolerance to transgenic corn plant. Also provided are assays for detecting the presence of the PV-ZMGT32(nk603) corn event based on the DNA sequence of the recombinant construct inserted into the corn genome and of genomic sequences flanking the insertion site. | 2012-12-27 |
20120329655 | ADJUVANTS AND METHODS OF USING THEM - Described herein are compositions comprising an acidifier intermixed with an emulsifier and a co-surfactant that form stable microemulsions in water. Also described are methods of dispersing a compound in an aqueous solution using the compositions of the present invention. | 2012-12-27 |
20120329656 | Formulation - A storage stable capsule suspension formulation comprising clomazone encapsulated within a polymeric shell wall of microcapsules, a process for the preparation thereof and method of controlling weeds utilizing said formulation. | 2012-12-27 |
20120329657 | METHODS AND DEVICES FOR THE PRODUCTION OF HYDROCARBONS FROM CARBON AND HYDROGEN SOURCES - Devices and methods are described for converting a carbon source and a hydrogen source into hydrocarbons, such as alcohols, for alternative energy sources. The influents may comprise carbon dioxide gas and hydrogen gas or water, obtainable from the atmosphere for through methods described herein, such as plasma generation or electrolysis. One method to produce hydrocarbons comprises the use of an electrolytic device, comprising an anode, a cathode and an electrolyte. Another method comprises the use of ultrasonic energy to drive the reaction. The devices and methods and related devices and methods are useful, for example, to provide a fossil fuel alternative energy source, store renewable energy, sequester carbon dioxide from the atmosphere, counteract global warming, and store carbon dioxide in a liquid fuel. | 2012-12-27 |
20120329658 | METHOD OF FORMING CERAMIC WIRE, SYSTEM OF FORMING THE SAME, AND SUPERCONDUCTOR WIRE USING THE SAME - Provided is a method of forming a ceramic wire. In the method, a ceramic precursor film is deposited on a wire substrate. Then, the wire substrate on which the ceramic precursor film is deposited is treated by heating. For treating the wire substrate by heating, a temperature of the wire substrate and/or an oxygen partial pressure of the wire substrate are controlled such that the ceramic precursor film is in a liquid state and an epitaxy ceramic film is formed from the liquid ceramic precursor film on the wire substrate. | 2012-12-27 |
20120329659 | SINTERING METHOD AND APPARATUS - A sintering apparatus comprising a container for holding small particles that contact one another, an electric current generator generating an alternating electric current and a flux concentrator having a collector positioned to be exposed to an alternating magnetic field generated by the alternating electric current and a tip that focuses the alternating magnetic field so that the particles are exposed to the alternating magnetic field, the alternating magnetic field heating surfaces of the particles so that they join and are fused together. | 2012-12-27 |
20120329660 | METHODS AND COMPOSITIONS FOR SORTING AND/OR DETERMINING ORGANISMS - This invention is directed to methods and compositions for sorting and/or determining microscopic organisms or cells. The methods and compositions are directed to the use of molecular probes to selectively stain the organisms or cells in combination with the use of binding partners to selectively immobilize the stained organisms or cells to a solid carrier. By combining the selectivity of both molecular probes and binding partners in an orthogonal method for staining and immobilization, these methods and compositions increase both the discriminating power of the assays and/or the certainty of the result obtained therefrom. | 2012-12-27 |
20120329661 | Isotope Labeling-Assisted Quantification (iLAQ) of Biological Compounds - The present invention relates to a plurality of isotopically labeled compounds (“tag isotopomers”) and individual labeled compounds, which are useful for labeling samples of analytes, such as biological compounds. The present invention further relates to methods of labeling and quantifying analytes using these tag isotopomers. | 2012-12-27 |
20120329662 | HYPOXIA TUMOUR MARKERS - The present invention relates to a method for assessing a hypoxia phenotype of a tumour of a subject in which the gene expression of between 3 and 50 hypoxia-related genes of a sample obtained from said tumour of the subject is determined, thereby obtaining a sample expression profile of said hypoxia-related genes. The sample gene expression profile is then compared with a reference expression profile of said hypoxia-related genes. The hypoxia-related genes comprise at least SLC2A1, VEGFA and PGAM1. Probes, arrays and kits for use in the method are also disclosed. | 2012-12-27 |
20120329663 | 14-3-3 sigma as a Biomarker of Basal Cancer - Methods and compositions for using 14-3-3sigma gene and protein as a highly sensitive and specific basal breast cancer biomarker, which when present, correlates with metastasis and poor outcome in independent patient cohorts. Methods and compositions for targeting 14-3-3sigma-regulated actin cytoskeletal interactions, activity and function may benefit patients having the basal-like breast cancer subtype. | 2012-12-27 |
20120329664 | MULTIPLEXED DIGITAL ASSAYS WITH COMBINATORIAL USE OF SIGNALS - System, including methods, apparatus, and compositions, for performing a multiplexed digital assay on a greater number of targets through combinatorial use of signals. | 2012-12-27 |
20120329665 | SYSTEMS AND METHODS FOR AUTOMATED ANALYSIS OF CELLS AND TISSUES - Systems and methods for rapidly analyzing cell containing samples, for example to identify morphology or to localize and quantitate biomarkers are disclosed. | 2012-12-27 |
20120329666 | Peripheral Blood Biomarkers for Idiopathic Interstitial Pneumonia and Methods of Use - The present invention provides methods for diagnosing several types of diseases. Specifically, the present disclosure provides a panel of diagnostic genes, the differential expression of whose mRNAs or proteins in the sample of a subject indicates the presence of the disease in the subject. The methods involve extracting mRNAs or proteins from the sample and performing gene expression profiling assays such as microarray assay, RT-PCR oligonucleotide binding array, quantitative RT-PCR assay, proteomics assay, and/or ELISA assay. | 2012-12-27 |
20120329667 | EPIGENETIC DNA ENRICHMENT - This application relates to methods for enriching DNA from a first cell type from a sample comprising DNA from the first cell type and DNA from a second cell type, wherein the first cell type methylates DNA to a lesser extent than the second cell type. DNA is enriched by, selecting for fragments by size after digestion of the sample with a methylation-sensitive restriction enzyme. Cell types of interest include fetal cells and cancerous cells. The enriched DNA can be used for a variety of procedures including, detection of a trait of interest such as a disease trait, or a genetic predisposition thereto, gender typing and parentage testing. | 2012-12-27 |
20120329668 | Biomarkers for Determining an Allograft Tolerant Phenotype - Methods are provided for determining whether a subject has a graft tolerant phenotype. In practicing the subject methods, the expression level of one or more gene in a sample from the subject, e.g., a blood sample, is assayed to obtain a gene expression result, where the gene expression result includes a result for a biomarker of graft tolerance. The obtained gene expression result is then employed to determine whether the subject has a graft tolerant phenotype. Also provided are compositions, systems and kits that find use in practicing the subject methods. The methods and compositions find use in a variety of applications, including the determination of an immunosuppressive therapy regimen. | 2012-12-27 |
20120329669 | USE OF DKK-1 PROTEIN IN THE CANCER DIAGNOSIS - Use of DKK-1 protein or the nucleic acid sequence in preparation of cancer diagnostic agents or kits, method to detect liver cancer with the monoclonal antibody thereof, the kit comprising anti-DKK-1 antibody or protein specific nucleic acid probes, together with a label, and method to detecting specific DKK-1 protein expression are disclosed. | 2012-12-27 |
20120329670 | EPITOPE TESTING USING SOLUBLE HLA - A methodology is provided for assaying the ability of a peptide of interest to displace an endogenously loaded peptide in a recombinantly produced, secreted, individual, soluble HLA trimolecular complex. | 2012-12-27 |
20120329671 | METHODS OF IDENTIFYING OBM MODULATORS - Novel proteins and polypeptides binding to osteoclastogenesis inhibitory factor (OCIF) (OCIF-binding molecules, OBMs) and nucleic acids encoding these proteins and polypeptides are provided. Processes for producing these proteins, polypeptides, and nucleic acid molecules by genetic engineering are provided. Medicinal compounds are provided which comprise proteins and nucleic acids according to the invention, as well as proteins which bind to OBM, including anti-OBM antibodies. These compounds may be used for the treatment of bone disease. | 2012-12-27 |
20120329672 | MicroRNA Expression Signature for Predicting Survival and Metastases in Hepatocellular Carcinoma - Provided herein are microarrays, kits, methods and compositions for the diagnosis, prognosis and treatment of Hepatocellular carcinoma (HCC). Also provided are methods of identifying anti-HCC agents. | 2012-12-27 |
20120329673 | VECTORS AND METHODS FOR SELECTING OPEN READING FRAMES - The invention provides vectors and methods designed for screening large random DNA fragment libraries for the presence of open reading frames that are free of both internal ribosome binding sites (IRBS) and stop codons. The invention overcomes the principal limitation of known ORF-selector systems, namely the potential for ORF-induced folding interference of the downstream fused reporter, by not fusing the reporter to the ORF, but rather by providing a mechanism for coupled translation of an unfused downstream reporter. | 2012-12-27 |
20120329674 | METHODS FOR LARGE SCALE FUNCTIONAL EVALUATION OF NUCLEOTIDE SEQUENCES IN PLANTS - The present invention provides for rapid and large scale evaluation of expression of, or function of, nucleotide sequences in plants. The invention comprises three specific components which provide for fast and large scale evaluation of nucleotide sequences. The first component includes delivery in either a single event a library of different engineered vectors or a single engineered vector for a single target nucleotide sequence comprising sequences the function of which is desired to be known in plant cells. Surprisingly, applicants have discovered that, the introduction of multiple vectors to plant cells predominantly results in individual transgenic plants which contain only a single transformation event. The second feature of the invention involves a highly transformable, fast cycling and/or miniature size plant and the final step involves mass scale analysis of T0 plants for various phenotypes and plasmid rescue to identify the nucleotide sequence present in a particular phenotype. | 2012-12-27 |
20120329675 | Testing of Biofilm for Anti-microbial Agent Susceptibility - This invention is an apparatus and method for susceptibility testing one or more biofilms, for selecting one or more anti-microbial combinations with efficacy against the biofilm, and/or in treating a disease or condition mediated by the biofilm The invention includes methods for the selection of antibiotic combinations with efficacy against a specific microbial type and for the formulation of microbe-specific test plates. The invention also includes an assay system to test patient specific isolates for sensitivity to the anti-microbial combinations. | 2012-12-27 |
20120329676 | HIGH THROUGHPUT SCREENING METHOD OF ACID-PRODUCING MICROORGANISM - A high throughput screening system and method of an acid-producing microorganism using a mixture of at least two pH indicators are provided. The method may be useful in determining a production amount of an acid, which is a final metabolite secreted by the microorganism, more accurately, rapidly and easily. | 2012-12-27 |
20120329677 | ARRAYS OF NUCLEIC ACID PROBES FOR DETECTING CYSTIC FIBROSIS - The invention provides arrays of immobilized probes, and methods employing the arrays, for detecting mutations in the CFTR gene. | 2012-12-27 |
20120329678 | Method for Making Mate-Pair Libraries - The present disclosure provides methods for generating mate-pair libraries using a recombinase/recombination site system. The method allows for increased insert size, improved efficiency and simplicity of the steps involved, and improved data generation. Mate-pair libraries are helpful in providing positional information for the assembly of sequence data from short read sequencing platforms. The disclosure also embodies the mate-pair libraries as generated from these methods. | 2012-12-27 |
20120329679 | EUKARYOTIC CELL DISPLAY SYSTEMS - The present invention provides expression vectors and helper display vectors which can be used in various combinations as vector sets for display of polypeptides on the outer surface of eukaryotic host cells. The expression vector of the invention can be used alone for soluble expression without having to change or reengineer the display vectors. The display systems of the invention are particularly useful for displaying a genetically diverse repertoire or library of polypeptides on the surface of yeast cells, and mammalian cells. | 2012-12-27 |
20120329680 | Metal (III) Complex Of Biuret-Amide Based Macrocyclic Ligand As Green Oxidation Catalyst - The present invention discloses metal (III) complex of a biuret-amide based macrocyclic ligand as green catalysts that exhibit both excellent reactivity for the activation of H | 2012-12-27 |
20120329681 | System and method for multiplex liquid handling - The present invention generally relates to microfabricated devices for carrying out and controlling chemical reactions and analysis. In particular, the present invention provides systems, methods, devices and computer software products related to multiplex liquid handling systems utilizing lab cards related to biological assays. | 2012-12-27 |
20120329682 | Drilling Fluid for Enhanced Rate of Penetration - A drilling fluid is provided which results in an enhanced rate of penetration, and more particularly, a drilling mud composition is provided with a reduced ester content which maintains an enhanced rate of penetration. | 2012-12-27 |
20120329683 | DEGRADABLE FIBER SYSTEMS FOR WELL TREATMENTS AND THEIR USE - A method for treating a subterranean formation penetrated by a wellbore is carried out introducing a treatment fluid into the formation through the wellbore wherein the formation has a formation temperature of at least 70° C. A composition for such treatment is also provided. The composition and treatment fluid for the method is formed from water and an amount of fibers formed from high temperature polymers of at least one of a polyester, polyamide, polyurethane, polyurea polymers, and copolymers of these. Each of said high temperature polymers is characterized by the property of not substantially degrading in water at a pH of from 5 to 9 at temperatures below 80° C. A fiber degrading accelerant that facilitates degrading of the fibers at the formation temperature is also included in the treatment fluid. | 2012-12-27 |
20120329684 | POLYMERIC GEL SYSTEM AND METHODS FOR MAKING AND USING SAME IN HYDROCARBON RECOVERY - Coacervate gels having excellent shear viscosities and other properties are made with anionic or cationic polymers, a smaller amount of a surfactant having a charge opposite that of the polymer, and a hydrophobic alcohol and an effective amount of a phosphorus-containing compound sufficient to increase the viscosity of coacervate gels up to 3 times as compared to the gels in the absence of the phosphorus-containing compound. The Zeta Potential of the gel is maintained at an absolute value of at least 20. Optional gel promoting additives include betaines and amine oxides. A preferred gel comprises poly diallyl dimethyl ammonium chloride, a lesser amount of sodium lauryl sulfonate, and lauryl alcohol. The gels are particularly useful in well drilling fluids and well fracturing fluids. | 2012-12-27 |
20120329685 | Particles Slurried in Oil for Viscoelastic Surfactant Gelled Fluids - Fluids viscosified with viscoelastic surfactants (VESs) may have their fluid loss properties improved with the presence of at least one mineral oil slurried together in combination with at least one particulate fluid loss control agent that may be an alkaline earth metal oxides, alkaline earth metal hydroxides, transition metal oxides, transition metal hydroxides, and mixtures thereof. The mineral oil having the particulate fluid loss control agents slurried within it may initially be dispersed oil droplets in an internal, discontinuous phase of the fluid. In one non-limiting embodiment, the slurry is added to the fluid after it has been substantially gelled. The mineral oil/particulate slurry may enhance the ability of a particulate fluid loss control agent to reduce fluid loss. The presence of the mineral oil may also eventually reduce the viscosity of the VES-gelled aqueous fluid. | 2012-12-27 |
20120329686 | NANOSTRUCTURES, THEIR USE AND PROCESS FOR THEIR PRODUCTION - A lubricating and shock absorbing materials are described, which are based on nanoparticles having the formula A | 2012-12-27 |
20120329687 | EXTREME PRESSURE ADDITIVES AND LUBRICANTS CONTAINING THEM - An extreme pressure additive for a lubricant may include one or more phosphorous containing compounds and one or more boron containing compounds. The ratio of weight of phosphorous to boron in the extreme pressure additive may vary between about 1 to about 30. | 2012-12-27 |
20120329688 | Antiwear Composition and Method of Lubricating Driveline Device - The present invention relates to a method of driveline device by supplying to the driveline device a lubricating composition containing an oil of lubricating viscosity and an antiwear package, wherein the antiwear package includes: (a) derivatives of a carboxylic acid (typically a hydroxycarboxylic acid); and (b) a phosphorus compound. The invention further provides lubricating compositions containing an oil of lubricating viscosity and an antiwear package, wherein the antiwear package includes (a) derivatives of a carboxylic acid (typically a hydroxycarboxylic acid); and (b) an amine or metal salt of a phosphorus compound that is either (i) a hydroxy-substituted di-ester of (thio)phosphoric acid, or (ii) a phosphorylated hydroxy-substituted di- or tri-ester of (thio)phosphoric acid. | 2012-12-27 |
20120329689 | Refrigeration Compressor Lubricant - The disclosed lubricant compositions comprise a mixture of from about 1-99% by weight of the mixture of one or more ester compounds | 2012-12-27 |
20120329690 | ADDITIVE COMPOSITION FOR ENGINE OIL - The disclosure relates to an additive composition including:
| 2012-12-27 |
20120329691 | Stabilized Blends Containing Friction Modifiers - The present invention relates to functional fluid compositions containing friction modifiers, and specifically stable compositions containing friction modifiers with limited solubility in and/or limited compatibility with the functional fluids with which they are used. In particular the present invention deals with functional fluids used in internal combustion engines, such as engine oils, and friction modifiers derived from hydroxy-carboxylic acids, where the friction modifier is present in the functional fluid composition at levels that would otherwise cause the composition to be unstable and/or hazy. | 2012-12-27 |
20120329692 | Wet Friction Clutch - Lubricant Systems Providing High Dynamic Coefficients of Friction Through the Use of Sodium Detergents - A wet friction clutch-lubricant system wherein a wet friction clutch having a cellulose-based friction lining, or a device including such a clutch, is lubricated with a lubricant composition a major amount of oil of lubricating viscosity and minor effective amounts of performance enhancing additives including (a) one or more ashless dispersant; (b) one or more organic phosphorus compound and (c) one or more sodium salt of an organic acid; and optionally, (d) an auxiliary friction modifier. | 2012-12-27 |
20120329693 | ADDITIVE FOR LUBRICATING OIL AND LUBRICATING OIL COMPOSITION CONTAINING SAME - Provided are an additive for lubricating oil, including a compound represented by the following general formula (1) as an essential component, and a lubricating oil composition blending same: | 2012-12-27 |
20120329694 | Lubricating Composition Containing Viscosity Modifier Combination - The present invention relates to a lubricating composition containing (a) an oil of lubricating viscosity, (b) a star polymer and (c) a substantially linear polymer with a weight average molecular weight of 45,000 or less. The invention further provides a method of lubricating a mechanical device, typically a manual transmission with the lubricating composition. The invention further provides for the use of the lubricating composition to provide a number of benefits including lower operating temperatures and fuel economy | 2012-12-27 |
20120329695 | LUBRICATING GREASE COMPOSITION - A lubricating grease composition for extreme pressure applications requiring extended lubrication intervals comprises a major amount of a lubricating base oil; a lithium complex thickener; and a polar compound selected from the group consisting of a rust inhibitor, a non-ionic surfactant, and mixtures thereof; wherein the concentration of the polar compound in the lubricating grease composition is no more than 0.5 wt. %, based on the total weight of the lubricating grease composition. | 2012-12-27 |
20120329696 | PERFUME SYSTEMS - The present application relates to perfume raw materials, perfume delivery systems and consumer products comprising such perfume raw materials and/or such perfume delivery systems, as well as processes for making and using such perfume raw materials, perfume delivery systems and consumer products. Such perfume raw materials and compositions, including the delivery systems, disclosed herein expand the perfume communities' options as such perfume raw materials can provide variations on character and such compositions can provide desired odor profiles. | 2012-12-27 |
20120329697 | STABLE POLYMER CONTAINING TWO PHASE SYSTEMS - The present invention relates to processes for producing stable polymer containing two phase systems, polymers for use in two phase systems as well as products comprising such systems and methods of making and using same. Such polymer containing two phase systems offer enhanced rheology and active delivery benefits without the stability negatives that are associated with the addition of polymers to two phase systems. | 2012-12-27 |
20120329698 | OPTICAL BRIGHTENERS AND COMPOSITIONS COMPRISING THE SAME - Novel compounds based on distyryl-biphenyl are provided. The compounds conform to the general structure | 2012-12-27 |
20120329699 | OPTICAL BRIGHTENERS AND COMPOSITIONS COMPRISING THE SAME - Novel compounds based on diaminostilbene are provided. The compounds conform to the general structures | 2012-12-27 |
20120329700 | SOLIDIFICATION MATRICES USING PHOSPHONOCARBOXYLIC ACID COPOLYMERS AND PHOSPHONOPOLYACRYLIC ACID HOMOPOLYMERS - Stability enhancement agents for use in a solidification matrices and solid detergent compositions are described. Stability enhancement is provided by a hydratable salt, water and phosphonocarboxylic acid copolymers or phosphonopolyacrylic acid homopolymers binding agents forming a dimensionally stable composition. Preferred phosphonocarboxylic acid copolymers or phosphonopolyacrylic acid homopolymers have phosphono end groups and a molecular weight of between about 1,000 and about 30,000 grams/mole. The stability enhancement composition for use in a solid detergent and solid detergent compositions are preferably biodegradable and substantially free of phosphorus and NTA-free. | 2012-12-27 |
20120329701 | AMINO SILICONE BASED ANTIFOAM AGENT AND ITS PROCESS OF MANUFACTURE - Modified aminoalkyl- and polyoxyalkylene-functional organopolysiloxanes exhibit delayed antifoaming activity in washing operations, minimizing foaming of rinse water. When applied to a pulverulent carrier, they may also be used in powder detergent formulations. | 2012-12-27 |
20120329702 | SOFTENER COMPOSITION - The present invention provides the softener composition containing the specific quaternary ammonium salts (I) and (II) each having a bis(polyalkoxyalkanol) structure, represented by the formulae (I) and (II) respectively, at a weight ratio of (I):(II) of 50.1:49.9 to 99.99:0.01. | 2012-12-27 |
20120329703 | Potent and Selective Mediators of Cholesterol Efflux - The present invention provides a family of non-naturally occurring polypeptides having cholesterol efflux activity that parallels that of full-length apolipoproteins (e.g., Apo AI and Apo E), and having high selectivity for ABAC1 that parallels that of full-length apolipoproteins. The invention also provides compositions comprising such polypeptides, methods of identifying, screening and synthesizing such polypeptides, and methods of treating, preventing or diagnosing diseases and disorders associated with dyslipidemia, hypercholesterolemia and inflammation. | 2012-12-27 |
20120329704 | PROCESS FOR THE PREPARATION OF SUBSTITUTED PROLYL PEPTIDES AND SIMILAR PEPTIDOMIMETICS - The present invention relates to a process for the stereoselective preparation of a compound having the general formula (I) or its respective diastereomers: comprising reacting a compound having the general formula (II) or its diastereomers: with a compound of the general formula III: R | 2012-12-27 |
20120329705 | COMPOUNDS FOR PROTEASOME ENZYME INHIBITION - Peptide-based compounds including heteroatom-containing, three-membered rings efficiently and selectively inhibit specific activities of N-terminal nucleophile (Ntn) hydrolases. The activities of those Ntn having multiple activities can be differentially inhibited by the compounds described. For example, the chymotrypsin-like activity of the 20S proteasome may be selectively inhibited with the inventive compounds. The peptide-based compounds include an epoxide or aziridine, and functionalization at the N-terminus. Among other therapeutic utilities, the peptide-based compounds are expected to display anti-inflammatory properties and inhibition of cell proliferation. | 2012-12-27 |
20120329706 | HEPATITIS B VIRUS PRE-S1 DERIVED SYNTHETIC POLYPEPTIDES AND USES THEREOF - The invention relates to a group of synthetic polypeptides, derived from the pre-S1 region of HBV, that efficiently interfere with early steps of an HBV infection. The peptides of the invention can be used in diagnostics for the detection of antigens and/or antibodies. | 2012-12-27 |
20120329707 | GLUCAGON/GLP-1 RECEPTOR CO-AGONISTS - Provided herein are peptides and variant peptides that exhibit enhanced activity at the GLP-1 receptor, as compared to native glucagon. | 2012-12-27 |
20120329708 | GLUCAGON/GLP-1 RECEPTOR CO-AGONISTS - Provided herein are peptides and variant peptides that exhibit enhanced activity at the GLP-1 receptor, as compared to native glucagon. | 2012-12-27 |
20120329709 | PRODUCTION OF GLYCOPROTEINS - The present invention provides methods and materials by which glycosylation of glycoproteins can be regulated. Methods include the monitoring and regulation of parameters such that a glycoprotein having a desired product quality is obtained. | 2012-12-27 |
20120329710 | Methods of Inducing Regulated Pancreatic Hormone Production in Non-Pancreatic Islet Tissues - Disclosed are methods and pharmaceutical compositions for inducing pancreatic hormone production. | 2012-12-27 |
20120329711 | GLP-1 RECEPTOR AGONIST COMPOUNDS WITH A MODIFIED N-TERMINUS - The invention relates to GLP-1 receptor agonist compounds with a modified N-terminus. The compounds are of the formula Chem. 1: Y—Z—P, wherein P represents a fragment of a GLP-1 receptor agonist peptide lacking the two N-terminal amino acid residues; and Y—Z represents novel His-Ala mimetics. Examples of GLP-1 receptor agonist compounds are derived from human GLP-1 (7-37), exendin-4(1-39), or GLP-1 A (1-37). The invention also relates to derivatives of these compounds, in particular compounds with one or more albumin binding side chains capable of protracting the duration of action in vivo of these compounds. The peptides and derivatives of the invention have a good potency, a protracted pharmacokinetic profile, are stable against degradation by gastro intestinal enzymes, and/or have a high oral bioavailability. These properties are of importance in the development of GLP-1 receptor agonist compounds for subcutaneous, intravenous, and/or in particular oral administration. The invention also relates to intermediate products for use in the preparation of the GLP-1 receptor agonist compounds of the invention. | 2012-12-27 |
20120329712 | Induction of Differential Stress Resistance and Uses Thereof - This invention relates to methods of inducing differential stress resistance in a subject with cancer by starving the subject for a short term, administering a cell growth inhibitor to the subject, or reducing the caloric or glucose intake by the subject. The induced differential stress resistance results in improved resistance to cytotoxicity in normal cells, which, in turn, reduces cytotoxic side-effects due to chemotherapy, as well as improved effectiveness of chemotherapeutic agents. | 2012-12-27 |
20120329713 | METHOD FOR DETERMINING LIKELIHOOD OF CLINICAL RECURRENCE OR CLINICALLY STABLE DISEASE OF PROSTATE CANCER AFTER RADICAL PROSTATECTOMY - This invention describes compositions and methods for use in PSA assays having low functional sensitivity which are useful, for example, in the detection of early stage recurrence of prostate disease following treatment and in the determination of whether patients have early stage biochemical reoccurrence (ES-BCR) or stable disease. | 2012-12-27 |
20120329714 | Prolactin Induced Increase in Neural Stem Cell Numbers - The present invention provides a method of increasing neural stem cell numbers or neurogenesis by using prolactin. The method can be practiced in vivo to obtain more neural stem cells in situ, which can in turn produce more neurons or glial cells to compensate for lost or dysfunctional neural cells. The method can also be practiced in vitro to produce a large number of neural stem cells in culture. The cultured stem cells can be used, for example, for transplantation treatment of patients or animals suffering from neurodegenerative diseases or conditions. In addition, since neural stem cells are a source for olfactory neurons, the present invention also provides methods of increasing olfactory neurons and enhancing olfactory functions. | 2012-12-27 |
20120329715 | GLP-1, EXENDIN-4, PEPTIDE ANALOGS AND USES THEREOF - The invention relates to novel polypeptide analogues of GLP-1 and exendin-4. The polypeptide, in a preferred embodiment, is insulinotropic and long-acting. Preferably, the polypeptide's insulinotropic effect is comparable to or exceeds the effect of an equimolar amount of GLP-1 or exendin-4. The invention also relates to a method of treating a subject with diabetes, comprising administering to the subject the polypeptide of the invention in an amount that has an insulinotropic effect. The invention also relates to methods of using GLP-1, exendin-4, and polypeptide analogues thereof for neuroprotective and neurotrophic effects. | 2012-12-27 |
20120329716 | YELLOW PEA SEED PROTEIN-DERIVED PEPTIDES - The instant invention relates to peptides obtained from the enzymatic hydrolysis of yellow pea seed proteins that are capable of lowering the blood pressure and reducing the effects of kidney disease in a subject b\ inhibiting or reducing the affinity of the enzymes in the renin-angiotensin system for their substrates, specifically renin, to compositions comprising said peptides and to uses thereof. | 2012-12-27 |
20120329717 | NOVEL OMEGA CONOTOXIN PEPTIDES - This invention relates to an isolated, synthetic or recombinant peptide, wherein the peptide comprises the sequence: C K G K G A Xaa | 2012-12-27 |
20120329718 | COMPOSITIONS AND METHODS FOR TREATING ATRIAL FIBRILLATION - The present invention provides compositions and methods for treating heart conditions. In particular, the present invention provides compositions and methods that block G protein coupled receptor mediated signaling for treating atrial fibrillation. | 2012-12-27 |