52nd week of 2009 patent applcation highlights part 41 |
Patent application number | Title | Published |
20090317742 | Photosensitive composition, method for forming pattern, and method for manufacturing semiconductor device - The present invention relates to a photosensitive composition, which is capable of being irradiated with high energy beam having a wave length of 1 to 300 nm band. The photosensitive composition includes a binder resin; and a photoelectron absorbent, capable of being excited with photoelectron emitted from the binder resin that absorbs the high energy beam, when the binder resin is irradiated with the high energy beam. | 2009-12-24 |
20090317743 | Resist composition for immersion exposure, method of forming resist pattern, and flourine-containing polymeric compound - A resist composition for immersion exposure including: a fluorine-containing polymeric compound (F) containing a structural unit (f1) having a base dissociable group and a structural unit (f2) represented by general formula (f2-1) (wherein R represents a hydrogen atom, a lower alkyl group or a halogenated lower alkyl group; and W is a group represented by any one of general formulas (w-1) to (w-4)); a base component (A) that exhibits changed solubility in an alkali developing solution under the action of acid; and an acid generator component (B) that generates acid upon exposure. | 2009-12-24 |
20090317744 | POLYMER AND CHEMICALLY AMPLIFIED RESIST COMPOSITION COMPRISING THE SAME - A polymer comprising a structural unit represented by the formula (Ia) or (Ib): | 2009-12-24 |
20090317745 | POSITIVE RESIST COMPOSITION AND METHOD OF FORMING RESIST PATTERN - Provided are a novel positive resist composition that includes a low molecular weight material as a base material component, and a method of forming a resist pattern using the positive resist composition. | 2009-12-24 |
20090317746 | PHOTOSENSITIVE RESIN COMPOSITION, PHOTOSENSITIVE ELEMENT COMPRISING THE SAME, METHOD OF FORMING RESIST PATTERN, AND PROCESS FOR PRODUCING PRINTED WIRING BOARD - ABSTRACT A photosensitive resin composition according to the invention comprises (A) a binder polymer, (B) a photopolymerizing compound with an ethylenic unsaturated group and (C) a photopolymerization initiator, wherein component (B) contains a compound represented by the following general formula (I). | 2009-12-24 |
20090317747 | ANTI-REFLECTIVE COATINGS USING VINYL ETHER CROSSLINKERS - Novel, wet developable anti-reflective coating compositions and methods of using those compositions are provided. The compositions comprise a polymer and/or oligomer having acid functional groups and dissolved in a solvent system along with a crosslinker and a photoacid generator. The preferred acid functional group is a carboxylic acid, while the preferred crosslinker is a vinyl ether crosslinker. In use, the compositions are applied to a substrate and thermally crosslinked. Upon exposure to light, the cured compositions will decrosslink, rendering them soluble in typical photoresist developing solutions (e.g., alkaline developers). | 2009-12-24 |
20090317748 | Method for Forming Fine Patterns of Semiconductor Device - A method for forming fine patterns of a semiconductor device employs a double patterning characteristic using a mask for forming a first pattern including a line pattern and a mask for separating the line pattern, and a reflow characteristic of a photoresist pattern. | 2009-12-24 |
20090317749 | METHOD FOR FORMING PATTERNS OF SEMICONDUCTOR DEVICE BY USING MIXED ASSIST FEATURE SYSTEM - Disclosed is a method for forming patterns of a semiconductor device, which includes: arranging dense patterns to be transferred in a dense pattern region of a wafer; inserting a first dummy pattern for restricting pattern distortion of the dense patterns in an outside of the array of the dense patterns; inserting a first assist feature for restricting pattern distortion of the first dummy pattern in an inside of the first dummy pattern; inserting an array of second assist features for additionally restricting pattern distortion of the first dummy pattern in an outside of the first dummy pattern, thereto designing a pattern layout to be transferred onto the wafer; and forming an array of the dense patterns and the first dummy patterns by transferring the pattern layout onto the wafer through an exposure. | 2009-12-24 |
20090317750 | METHOD FOR MANUFACTURING PIEZOELECTRIC/ELECTROSTRICTIVE FILM TYPE ELEMENT - A manufacturing method for a piezoelectric/electrostrictive film type element and a film constituting a laminated vibrator made of laminations of an electrode film and a piezoelectric/electrostrictive film in a plane position. The piezoelectric/electrostrictive film type element includes a substrate, a lower electrode film provided on the substrate, and a laminated vibrator made of laminations of a piezoelectric/electrostrictive film and an upper electrode film. The lower electrode film is formed by a photolithography method with the substrate, where a cavity is filled with a light shielding agent, as a mask. Thereafter, the piezoelectric/electrostrictive film is formed by electrophoresis of powder of a piezoelectric/electrostrictive material toward the lower electrode film, and the upper electrode film is formed by the photolithography method with the piezoelectric/electrostrictive film as a mask. The piezoelectric/electrostrictive film may be formed by the photolithography method with the lower electrode film as a mask. | 2009-12-24 |
20090317751 | Optical arrangement of autofocus elements for use with immersion lithography - A lithographic projection apparatus includes an optical element through which a substrate is exposed with an exposure beam. A space between the optical element and the substrate is filled with liquid during the exposure. A gap is formed between a member and a surface of the optical element through which the exposure beam does not pass. The liquid is supplied to the gap. | 2009-12-24 |
20090317752 | Rinse liquid for lithography and method for forming resist pattern using same - The present invention provide with a rinse solution for lithography and a resist pattern forming method using the same, which can prevent an inclination and peeling-off of a resist pattern and form a resist pattern having a high aspect ratio with high reproducibility. The rinse solution for lithography of the present invention comprises water and a nonionic surfactant having an ethyleneoxy group but not having a fluorine atom. The resist forming method of the present invention comprises the step of rinsing the pattern after development treatment with the rinse solution for lithography. | 2009-12-24 |
20090317753 | BICYCLO COMPOUND, METHOD FOR PRODUCING PENTACENE AND A FILM THEREOF USING THE SAME, AND METHOD FOR PRODUCING BICYCLO COMPOUND - A method for producing highly purified fused aromatic ring compounds with high yield by a simpler method. A method for producing a fused aromatic ring compound comprising irradiating the bicyclo compound containing at least one bicyclo ring represented by formula (1) in a molecule with light to detach a leaving group X from a residual part to form an aromatic ring: | 2009-12-24 |
20090317754 | Flare gas flammability control - A plant gas to be flared in the atmosphere is periodically sampled and analyzed as to its Btu content, a first comparison made of 1) the most recent of such analyses with 2) a predetermined steady state set point, a second comparison made of 3) an average of a plurality of such analyses including an historical minimum Btu content with 4) a predetermined dynamic set point, and fuel added to the plant gas based on the larger fuel requirement of these first and second comparisons. | 2009-12-24 |
20090317755 | Hot Surface Igniter Adaptive Control Method - An adaptive gaseous fuel ignition control method for use in consumer and commercial appliances that reduces stress on and increases the life of a hot surface igniter without resulting in a failure to ignite condition is provided. The method provides a preheating period, a full temperature period, and a trial for ignition period. The preheating period gradually increases the power applied to reduce the stress resulting therefrom. Once a gas valve has been commanded open, the controller monitors the time for ignition of the gaseous fuel. If the time is longer than a threshold, either the applied power or the period of time during which the power is applied is increased to shorten the time. If, however, the ignition period is shorter than the threshold, either the power applied or the period of time during which the power is applied before commanding the gas valve open is lowered or shortened. | 2009-12-24 |
20090317756 | DIGITAL HIGH TURNDOWN BURNER - A gas burner system for a heating device includes a burner, a valve assembly for controlling a flow of fuel to the burner, a blower assembly for directing air to the burner, and a control system. The burner includes one or more burner plates for facilitating the mixture of air and fuel to be combusted in a combustion chamber. The control system is configured to independently control the valve assembly and the blower assembly according to a control profile, for generating a plurality of air/fuel mixtures each configured for operation of the burner at a different firing rate. By mapping the characteristics of both the gas valve and the combustion blower independently, the burner system is assured of operating at the proper air/fuel mixture over a very wide range of firing rates, with a turndown ratio of 30:1 or greater, and within ANSI safety and performance standards. | 2009-12-24 |
20090317757 | Method for Using Radio Frequency Identification Microchips in Orthodontic Brackets - The following invention is an apparatus and method for quickly determining the type of bracket implanted on patient's tooth. A radio frequency identification (RFID) microchip is coupled to or in an orthodontic bracket. The bracket or series of brackets are then implanted on the patient's teeth as required. With the RFID in or on the bracket, the orthodontist or staff uses a scanner to read the brackets. The information read by the scanner allows the staff to select the correct corresponding bracket needed for replacement from an inventory. Confirmation of the correct selection is obtained by another scan from another scanner located in the bracket holding device. Not only does this process ensure that the correct replacement bracket is received by the patient, but also provides the orthodontist and staff with a real-time tracking of inventory supply. | 2009-12-24 |
20090317758 | BRUSHHEAD ASSEMBLY-HANDLE INTERFACE ARRANGEMENT FOR A DROPLET JET SYSTEM FOR CLEANING TEETH - The interface structure includes a handle portion ( | 2009-12-24 |
20090317759 | Micro-Abrasive Blasting Device for Dental Applications and Methods - A micro-abrasive blasting device comprises a mixing chamber, a delivery conduit extending from external the mixing chamber to the mixing chamber and a discharge conduit extending from the mixing chamber. Abrasive material may selectively be sealed in the chamber by positioning the discharge conduit to abut the inlet port. The chamber may be spherical to deliver consistent powder perturbation at all mixing chamber orientations. Methods of using the device are disclosed. Methods of making the device by blow molding are disclosed. | 2009-12-24 |
20090317760 | MULTI-LUMEN ASPIRATOR DEVICE - A multi-lumen aspirator device having an elongated body with a plurality of lumens disposed therein for reducing the sound level generated during the operation of the device is disclosed. The elongated body defines a proximal opening that communicates with a distal opening through an inner conduit. The plurality of lumens is disposed within the inner conduit such that a central lumen of the plurality of lumens is surrounded by the remaining plurality of lumens such that laminar flow is established through the multi-lumen aspirator that promotes the reduction in sound generated by the multi-lumen aspirator device during operation. | 2009-12-24 |
20090317761 | Stabilizer for tooth prostheses - A stabilizer for tooth prostheses, consisting of a double torsion spring, the arms ( | 2009-12-24 |
20090317762 | IMPLANTS WITH POROUS OUTER LAYER, AND PROCESS FOR THE PRODUCTION THEREOF - Provided are implants having a porous coating, comprising an implant core made of solid material and a sleeve fitted thereon, wherein the sleeve comprises an outer porous region in addition to an inner non-porous region. The invention further provides a method for joining the solid implant core and a sleeve comprising an outer porous region as well as an inner non-porous region. | 2009-12-24 |
20090317763 | IMPLANT ARRANGEMENT - An anchoring arrangement is provided for anchoring a dental prosthesis to a patient. The arrangement can comprise an implant, a sleeve, and a fastening screw. The implant can comprise a coronal portion and an apical portion. The apical portion can be configured to extend from within a jaw bone and into a zygoma. The coronal portion can include a substantially planar surface extending transversely relative to a longitudinal axis of the apical portion and a threaded aperture. The threaded aperture can extend from the substantially planar surface into the implant transversely relative to the longitudinal axis of the apical end of the implant. The sleeve can comprise an end portion configured to mate with the substantially planar surface of the implant. The fastening screw can be disposed through the sleeve and fastened to the threaded aperture. | 2009-12-24 |
20090317764 | Endosteal Dental Implant - One aspect of the invention concerns a one-piece endosteal dental implant ( | 2009-12-24 |
20090317765 | SUPRAOSSEOUS DENTAL IMPLANT - The present invention relates to a supra-osseous dental implant ( | 2009-12-24 |
20090317766 | Structured coatings for implants and process for the preparation thereof - The invention relates to a method for producing a powder-filled ceramic coating made from a precursor ceramic compound (for example, a sol-gel), said coating having an advantageous surface roughness and wherein active ingredients may be eluted from the matrix or filler under physiological conditions and to an implant which can be produced according to the claimed method. | 2009-12-24 |
20090317767 | Material based on a partially stabilized zirconia matrix and process for the preparation and use of the material - A material comprising: from 98-50% by volume of zirconia as a matrix, which is stabilized with i) either of from about 2 to about 3 mole percent of yttria ii) or of from about 10 to about 15 mole percent of ceria; iii) or a mixture of ceria and yttria in the range of amounts as given in i) and ii) the stabilizing oxides may be substituted against each other in a ratio from 1:99 to 99:1 and a maximum stabilization of 3 mole percent related to pure yttria and 15 mole percent related to pure ceria respectively are not exceeded, and wherein the term mole percent is related to the zirconia matrix and wherein the zirconia matrix is obtainable from a) a powder of particles of zirconia having a mean particle size of <0.35 μm, b) the particles are coated with the stabilizing oxides yttria and/or ceria for stabilizing zirconia, c) a stabilization of the tetragonal phase is performed via a diffusion reaction by a sintering process, and from about 2 to about 50% by volume of alumina of which from about 5 to about 90% by volume is in the form of hexagonal platelets of general formula REAl | 2009-12-24 |
20090317768 | IMPLANT, METHOD OF PREPARING AN IMPLANT, IMPLANTATION METHOD, AND KIT OF PARTS - An implant according to the invention includes first thermoplastic material portions, and second thermoplastic material portions liquefiable by mechanical vibrations and being in contact with the first thermoplastic material portions, wherein the second thermoplastic material portions preferably constitute at least a part of a surface of the implant, and wherein the first thermoplastic material portions have a glass transition temperature above an implantation temperature (about 20° C. to 40° C.), and wherein the second thermoplastic material portions either have a glass transition temperature below said implantation temperature or include means for transforming non-mechanical energy into heat. | 2009-12-24 |
20090317769 | RESILIENT COPING FOR IMMEDIATE LOADING OF DENTAL IMPLANTS - A resilient coping for use in the immediate loading of a newly placed dental implant with a temporary tooth has a resilient liner to prevent movement of the temporary tooth mounted on the resilient coping from being transmitted to the implant, thereby promoting its osseointegration. | 2009-12-24 |
20090317770 | User Health Profiles Derived From Oral Care Implements - A computer-implemented method includes a step of presenting an indication of a health profile of a person based on information obtained from an oral care implement. Also, a method includes displaying an indication of a history of the health profile of a a person based on second information previously received from the oral care implement. | 2009-12-24 |
20090317771 | IMPLANT REMOVAL TOOL - Implant removal tool ( | 2009-12-24 |
20090317772 | DENTAL COMPOSITIONS WITH CALCIUM PHOSPHORUS RELEASING GLASS - The present application provides dental compositions, and methods of making and using dental compositions that include a calcium and phosphorus releasing glass. Such dental compositions can be useful for delivering ions to the oral environment. | 2009-12-24 |
20090317773 | Variably Transmittive, Electronically-Controlled Eyewear - A system and method for flight training and evaluation of pilots comprises electronically activated vision restriction glasses that detect the pilot's head position and automatically darken and restrict the pilot's ability to see through the front and side windscreens when the pilot-in-training attempts to see out the windscreen. Thus, the pilot-in-training sees only within the aircraft cockpit, forcing him or her to fly by instruments in the most restricted operational mode. | 2009-12-24 |
20090317774 | METHOD AND APPARATUS FOR CREATING PERSONALIZED ART - An application for a method and apparatus for creating a work of art includes providing an artistic kit that has a source of a pigment and an applicator. The applicator accepts the pigment and is used to apply the pigment to a unique part of a user's anatomy. The kit includes at least one artistic medium having a pre-printed design on a front side and a location adapted to accept an impression of the unique part of a user's anatomy. The applicator is used to coat the unique part of a user's anatomy with the pigment, then the unique part of a user's anatomy with the pigment is pressed onto the location adapted to accept an impression within the pre-printed design, thereby creating a work of art unique to the user. | 2009-12-24 |
20090317775 | EDUCATIONAL INTERACTIVE GAMES - An educational interactive game of the invention includes a system for teaching financial skills to players, and in particular, children in the context of an interactive electronic game. Each player is initially provided a predetermined amount of periodic earned income, periodic expenses and a predetermined amount of cash on hand. These items are represented by corresponding indicia on an electronic display. An object of the game is for a player to generate passive income greater than the player's expenses by encountering game events that provide a player the opportunity to make financial choices to affect the desired outcome. | 2009-12-24 |
20090317776 | Economic Language Learning System - A system of language learning applies economic theory to provide speakers and learners of each of plural languages. Remote users teach the native languages to one another by providing practice time for users seeking to learn such language. A computer keeps track of the value and cost of teaching and learning time in each language. | 2009-12-24 |
20090317777 | Educational Systems and Methods for Learning How to Spell - Educational systems and methods for learning how to spell are provided. In this regard, a representative system includes: a working surface including a representation of a hand having five fingers; five sets of vowels “a”, “e”, “i”, “o” and “u” depicted at the working surface, each of the sets being associated with a corresponding one of the fingers; and five spelling locations depicted at the working surface, each of the locations being associated with a corresponding one of the fingers. | 2009-12-24 |
20090317778 | Public Library System for Providing Reading-Together at Two Remote Locations of a Selected Children Literature Item - The invention relates to an electronic public library system for providing reading together of an electronic children literature item at two remote computers, which comprises: (a) an adult computer and a child computer that are located remote one from the other, and are connected to the Internet; (b) two mouse pointing devices, one at each of said computers; (c) a camera and microphone at each of said computers for producing an adult live video channel and child live video channel from each of said adult and child computers respectively; and (d) a library server which comprises: (i) storage for storing a collection of children literature items for selection; (ii) a user interface for enabling access, and selection of an item from a first of said adult or child computers; (iii) item processing unit for (I) establishing communication with said two computers; (II) receiving the adult and child video channels from said adult and child computers respectively; (III) activating the selected children literature item; (IV) receiving mouse locations from each of said two computers from a synchronization unit; (V) sending synchronized images simultaneously to both of said adult and child computers, wherein the images sent to each of said two computers comprise the same literature item image at a first screen portion, mouse indicators of said two computers distinguished one from the other by shape, and for each party, a live video display of the other party positioned at a second screen portion; and (iv) a synchronization unit for receiving control instructions over the literature item from each of said computers, and mouse location from each of said | 2009-12-24 |
20090317779 | TIME-OUT EDUCATIONAL SYSTEM - A method of educating a child during a time-out period. A caregiver identifies a child misbehaving and isolates the child from any distractions. The caregiver then selects an educational time-out presentation from a plurality of educational time-out presentations by topic based on the child's misbehavior. After the child views the educational time-out video, caregiver continues to monitor the child to confirm if the child is behaving in accordance with the educational time-out video. Each educational time-out presentation includes a non-threatening yet authoritative figure that leads the child through an educational process using visual, auditory, and kinesthetic methods wherein the child learns to make more appropriate decisions about how to behave. | 2009-12-24 |
20090317780 | Tooth for Dental Arch Model and Method for Producing the Same - The present invention relates to a tooth which is used in a dental arch model with which dental students can experience dental works in the oral cavity and practice treatments. More specifically, the present invention relates to a tooth composition for formation trainings such as abutment tooth formation and cavity preparation. Since conventionally used dental arch models have a grinding sensation different from a natural tooth, dental students having completed formation trainings such as abutment tooth formation and cavity preparation by using these conventional models are frequently puzzled to have different grinding and handling properties upon dental works in the oral cavity in practice. That is, these conventional dental arch models are largely different from a natural tooth in grinding sensation including slipperiness and easiness in grinding. A tooth for a dental arch model simulating the enamel texture and the dentin texture constituting a natural tooth whereby even the difference in grinding sensation between the enamel texture and the dentin texture constituting a natural tooth can be reproduced by forming at least the enamel portion with the use of a sintered body of an inorganic powder such as alumina. | 2009-12-24 |
20090317781 | MEDICAL INSTRUCTION SYSTEM - The invention relates to a method, system, method of doing business, and computer program product for providing instruction and device training. More particularly, the invention provides information and training around medical, veterinary and anatomical procedures. The procedures are presented as a multimedia interactive platform to provide improved instruction and training. | 2009-12-24 |
20090317782 | Big Canyon Balloon - An educational tool for teaching students may include a tarp portion, an inflatable being positioned on the tarp portion, the inflatable portion including a first end section positioned on a first end of the inflatable portion, a river section connected to the first end section, a middle section connected to the river section, and a second end section connected to the middle section. The river section may include a top river section and a bottom river section, and the top river section may be independently inflatable with respect to the bottom river section. The first end section may include a first contour portion, and the middle section may include a second contour portion. The second end section may include a third contour portion to cooperate with the second contour portion, and the second end section may include a fourth contour portion. The river portion may include a pullout portion, and the educational tool may include a tunnel baffle adapted to allow users to walk in a passageway of the tunnel baffle. The tunnel baffle may cooperate with the middle and second end section in order to form a classroom. | 2009-12-24 |
20090317783 | SONG PRACTICE SUPPORT DEVICE - A technique of enabling a singer to auditorily recognize how to change the way of singing is provided. The CPU ( | 2009-12-24 |
20090317784 | Remote delivery system and remote delivery method - A remote delivery system for delivering a lecture content given by an instructor to a remote location preliminarily, converts an instructor's document to an animation file, delivers to a student's terminal, automatically delivers, from the starting of a lecture, image sound data including an image and sound of the instructor, the number of the instructor's document selected by the instructor, location data of a pointer on a screen, character or figure data drawn on a whiteboard by the instructor and animation information included in the instructor's document, and displays on the student's terminal in real time by comparing an instructor document number and an animation information number preliminarily written in the animation file with delivered numbers. | 2009-12-24 |
20090317785 | TEST SYSTEM - In an exemplary embodiment, a computer-implemented method for implementing a test delivery system is provided. The method includes implementing a plurality of interoperable accommodation and accessibility tools, and providing an interface to the test with the plurality of interoperable accommodation and accessibility tools provided on the interface. The method also includes receiving one or more tool settings for a test-taker specifying one or more permitted tools in the plurality of interoperable accommodation and accessibility tools, and customizing the interface based on the one or more tool settings to allow the test-taker access to the one or more permitted tools during the test. The method further includes allowing the test-taker to activate or deactivate each of the one or more permitted tools. | 2009-12-24 |
20090317786 | INTERNET-BASED EDUCATION SUPPORT SYSTEM AND METHODS - A system and methods for implementing education online by providing institutions with the means for allowing the creation of courses to be taken by students online, the courses including assignments, announcements, course materials, chat and whiteboard facilities, and the like, all of which are available to the students over a network such as the Internet. Various levels of functionality are provided through a three-tiered licensing program that suits the needs of the institution offering the program. In addition, an open platform system is provided such that anyone with access to the Internet can create, manage, and offer a course to anyone else with access to the Internet without the need for an affiliation with an institution, thus enabling the virtual classroom to extend worldwide. | 2009-12-24 |
20090317787 | METHOD FOR CREATING PERFUSABLE MICROVESSEL SYSTEMS - Creating a tissue structure in vitro includes juxtaposing mandrels on a culture/perfusion device frame where the mandrels are spaced apart substantially parallel to each other and connecting the mandrels to tubes including an upstream tubes and downstream tubes. The upstream tubes are connected with an upstream manifold and the downstream tubes are connected to a downstream manifold. The frame and the mandrels are sterilized, coated and seeded with cells that multiply and form circular layers around each of the mandrels until the circular layers merge into a tissue structure which is subjected to a growth medium. The mandrels are extracted and the tissue structure is perfused. | 2009-12-24 |
20090317788 | Novel Carbohydrate Profile Compositions From Human Cells and Methods for Analysis and Modification Thereof - The present invention discloses a method of evaluating the status of a stem cell preparation comprising the step of detecting the presence of a glycan structure or a group of glycan structures in said preparation. The detection step can be performed by the use of a lectin specific to a glycan structure of interest. | 2009-12-24 |
20090317789 | METHOD FOR QUANTIFYING A CELL POPULATION OF INTEREST CONTAINED IN A HUMAN BLOOD SAMPLE - The present invention provides to a method for quantifying a cell population of interest contained in a human blood sample, comprising the steps of: contacting a sample of human blood with a cocktail comprising a first component, comprising at least one non-human antibody, antibody fragment or derivative thereof, capable of specifically binding to an antigen expressed on the surface of a first cell population distinct from a second cell population, said second cell population being the cell population of interest and being devoid of said antigen, complexed to a second component, comprising at least one non-human antibody, antibody fragment or derivative thereof, capable of specifically binding to the surface of human erythrocytes; separating antibody-labelled from unlabelled cells contained in the blood sample; collecting the supernatant comprising the second cell population; concentrating the second cell population contained in the supernatant and resuspending said cell population in a liquid capable of selectively lysing erythrocytes; concentrating the obtained cells, essentially removing all supernatant and resuspending said cells in a defined volume of physiological buffer; and determining the number of the cells of the second cell population contained in the sample. Furthermore, the invention provides to a kit for performing the method of the invention. | 2009-12-24 |
20090317790 | Method for the Production of Frozen Blood or Frozen Blood Cells for Biological Assays - The present invention relates to an improved method for cryo-preservation of human whole blood containing monocytes and lymphocytes at temperatures of between −40° C. and −60° C., preferably at −60° C., whereby the function of monocytes and lymphocytes is preserved. The present invention, particularly relates to a method for cryo-preservation of human whole blood containing monocytes and lymphocytes without the need for an isolation of peripheral blood mononuclear cells (PBMCs), or blood cells. | 2009-12-24 |
20090317791 | Methods and apparatus for performing retention-time matching | 2009-12-24 |
20090317792 | OIL EMULSIONS AND METHODS FOR MANUFACTURE AND USE THEREOF - The invention provides oil emulsion droplets and a general and facile method for providing same through the use of templating multilayer capsules. The oil emulsion droplets are further useful in fabricating liquid crystal droplet-based biosensors for the detection of target analytes such as bacteria or viruses in a sample. | 2009-12-24 |
20090317793 | MICROFLUIDIC DEVICE AND A MICROFLUIDIC SYSTEM AND A METHOD OF PERFORMING A TEST - A microfluidic device comprising at least one test channel, which test channel comprises an upper test channel section with an upstream end and a sampling region at its upstream end and at least one reference channel, which reference channel comprises an upper reference channel section with an upstream end and a sampling region at its upstream end. The test channel and the reference channel comprise a merging region downstream to the upper test channel section and a common downstream channel section. The merging region and the common downstream channel section are arranged such that a reference liquid flowing from the upper reference channel section into the merging region will block a test liquid flow in the upper test channel section when the test liquid flow has not yet reached the merging section. The microfluid device may be used for detecting change of flow properties e.g. due to agglomeration, agglutination or viscosity change in a liquid preferably selected from water, urine, blood, or blood plasma. | 2009-12-24 |
20090317794 | BIOLOGICAL INDICATOR - A kinase is used in a biological indicator for validation of treatment processes designed to reduce the amount or activity of a biological agent in a sample. The indication can be used for validation of sterilisation treatment. The formation of ATP from a substrate comprising ADP is measured via the liciferin/luciferate system in a luminameter. Thermostable adenylate kinase from | 2009-12-24 |
20090317795 | METHOD OF DETECTING H5 OR H7 AVIAN INFLUENZA VIRUS - The present invention provides oligonucleotide primers specifically hybridizing to an arbitrary nucleotide sequence designed from the nucleotide sequence of hemagglutinin of an H5 or H7 avian influenza virus, a nucleic acid amplification method using the primers, a method for diagnosis of infection with an H5 or H7 avian influenza virus by detection of nucleic acid amplification, and a kit for influenza diagnosis. | 2009-12-24 |
20090317796 | Indirect immunofluorescence assay typing kit for coxsackievirus A group and method for typing coxsackievirus A group - An indirect immunofluorescence assay typing kit for coxsackievirus, comprising: a first reagent comprising a mixture of an anti-coxsackievirus A2 polyclonal antibody, an anti-coxsackievirus A4 polyclonal antibody, an anti-coxsackievirus A5 polyclonal antibody, an anti-coxsackievirus A6 polyclonal antibody, and an anti-coxsackievirus A10 polyclonal antibody; a second reagent comprising the anti-coxsackievirus A2 polyclonal antibody; a third reagent comprising the anti-coxsackievirus A4 polyclonal antibody; a fourth reagent comprising the anti-coxsackievirus A5 polyclonal antibody; a fifth reagent comprising the anti-coxsackievirus A6 polyclonal antibody; a sixth reagent comprising the anti-coxsackievirus A10 polyclonal antibody; and a seventh reagent comprising a secondary antibody labeled with a fluorescence compound, wherein the secondary antibody is used for detecting the antibody anti-coxsackieviruses A2, A4, A5, A6 and A10 polyclonal antibodies and a titer of the anti-coxsackieviruses A2, A4, A5, A6 or A10 polyclonal antibody is about 1:5000-151:70000. | 2009-12-24 |
20090317797 | Non-Invasive, Prenatal, In-Vitro Method for Detecting the Normal Healthy Condition, the Condition of a Healthy Carrier or the Condition of a Carrier Inflicted with Cystic Fibrosis - The invention relates to a non-invasive, prenatal, in-vitro method for detecting the normal healthy condition, the condition of a healthy carrier or the condition of a carrier inflicted with cystic fibrosis, from the fetal cell(s) from a maternal sample, comprising the DNA of an individual to be tested. The invention also relates to oligonucleotide primers and to their use within the scope of a non-invasive, prenatal, in-vitro method for detecting the condition of a healthy carrier or of a carrier inflicted with cystic fibrosis. | 2009-12-24 |
20090317798 | ANALYSIS USING MICROFLUIDIC PARTITIONING DEVICES - The invention relates to methods, reagents and devices for detection and characterization of nucleic acids, cells, and other biological samples. Assay method are provided in which a sample is partitioned into sub-samples, and analysis of the contents of the sub-samples carried out. The invention also provides microfluidic devices for conducting the assay. The invention also provides an analysis method using a universal primers and probes for amplification and detection. | 2009-12-24 |
20090317799 | Variants at chr8q24.21 confer risk of cancer - A locus on chromosome 8q24.21 has been demonstrated to play a major role in particular forms of cancer. It has been discovered that certain markers and haplotypes are indicative of a susceptibility to particular cancers. Diagnostic applications for identifying susceptibilty to cancer are described. | 2009-12-24 |
20090317800 | REPORTER VECTOR FOR USE IN EVALUATION OF CYP1A2 INDUCTION - A reporter vector which can evaluate the ability of a drug to induce CYP1A2 or both of CYP1A1 and CYP1A2 and a method for evaluation of the ability of a drug to induce CYP1A2 or both of CYP1A1 and CYP1A2 by using the reporter vector. A reporter system which can evaluate the ability of a drug capable of inducing CYP1A2 or both of CYP1A1 and CYP1A2 is completed by constructing a reporter vector having a reporter gene linked to the 3′ end of a region between CYP1A1 and CYP1A2 or a reporter vector having different reporter genes linked to the both ends of the region, respectively, so as to sandwich the region, and a reporter vector having a deletion mutation in the region, and confirming that the expression of a reporter molecule is increased by the drug capable of inducing CYP1A2 or both of CYP1A1 and CYP1A2 in the reporter system using the reporter vector. | 2009-12-24 |
20090317801 | METHODS AND COMPOSITIONS FOR DISEASE PROGNOSIS BASED ON NUCLEIC ACID METHYLATION - A large scale DNA methylation study was performed in patients with acute myeloid leukemia (AML) that revealed quantitative methylation patterns correlated with patient survival. Based on these results, a prognostic model was built which categorizes a patient's risk—either in a good or poor prognosis group. The findings provided herein support the use of genomic methylation markers for improved molecular classification and disease management in adult AML. Also, the results provide insight into the pathophysiology of AML and offer novel AML gene targets. Thus provided are methods and compositions for the prognosis of a subject suffering from acute myeloid leukemia (AML) based on the methylation state of nucleic acids. The methods may used alone to determine a patient's prognosis or in combination with other prognostic factors or markers such as gene expression. | 2009-12-24 |
20090317802 | Compositions and Methods to Monitor RNA Delivery to Cells - Methods and compositions for tracking or monitoring uptake of siRNA by mammalian cells are provided. The methods and compositions may be used to monitoring the silencing activity of the internalized siRNA. The compositions contain an siRNA, an optically or magnetically detectable nanoparticle such as a quantum dot and, optionally, a transfection reagent. Cells are contacted with an siRNA and an optically or magnetically detectable nanoparticle, optionally in the presence of a transfection reagent. Detection of internalized nanoparticles is indicative of siRNA uptake. The invention allows analysis, identification, processing, etc., of cells that have efficiently taken up siRNA. In one embodiment, cells are sorted into at least two populations based on the amount of siRNA taken up. | 2009-12-24 |
20090317803 | ENZYMATIC TIME-RESOLVED LUMINESCENT ASSAY FOR NUCLEIC ACIDS QUANTITATION - The objects of the present invention are to provide a new technology platform for quantitation number of copies of nucleic acid molecules of interest by lumonogenic (i.e., enzymatic luminescence) detection. The detection approach of the method of present invention is essentially employing time-resolved approach, e.g., based on detection transient parameters of luminescent signal. The various disclosed embodiments allow DNA and RNA quantification in a broad dynamic range; can be used for detection of DNA, as well as long (mRNA) and short (microRNA) RNA targets. The present invention provides methods, instruments, and kits for fast and highly sensitive identification and measurements of nucleic acids in various life science and biomedical applications. | 2009-12-24 |
20090317804 | METHODS OF DETERMINING ANTIBIOTIC RESISTANCE - This disclosure relates to methods of determining an antibiotic resistance profile of a bacterium, and methods of treating a patient with a therapeutically effective antibiotic. The methods include comparing the restriction map of the nucleic acid with a restriction map database, and determining antibiotic resistance of the bacterium by matching regions of the nucleic acid to corresponding regions in the database. | 2009-12-24 |
20090317805 | Proteolytic Markers as Diagnostic Biomarkers for Cancer, Organ Injury and Muscle Rehabilitation/Exercise Overtraining - The present invention identifies biomarkers that are diagnostic of nerve cell injury, organ injury, and/or neuronal disorders. Detection of different biomarkers of the invention are also diagnostic of the degree of severity of nerve injury, the cell(s) involved in the injury, and the subcellular localization of the injury. | 2009-12-24 |
20090317806 | SYSTEMS AND METHODS FOR MONITORING THE AMPLIFICATION OF DNA - A system and method for amplifying and detecting nucleic acids are disclosed. In one embodiment, the system includes: a microfluidic device comprising a channel for receiving a sample of solution containing real-time PCR reagents; a temperature control system configured to cycle the temperature of the sample; an excitation source for illuminating the sample; a fiber optic probe comprising (i) an optical fiber having a distal end and a proximal end and (ii) a probe head connected to the distal end of the optical fiber and positioned between the distal end of the optical fiber and the channel; and a detector configured to detect emissions exiting the proximal end of the optical fiber. | 2009-12-24 |
20090317807 | Primers for Use in Detecting Metallo-Beta-Lactamases - Oliognucleotide primers are provided that are specific for nucleic acid characteristic of certain beta-lactamases. The primers can be employed in methods to identify nucleic acid characteristic of family-specific beta-lactamase enzymes in samples, and particularly, in clinical isolates of Gram-negative bacteria. | 2009-12-24 |
20090317808 | NOVEL NUCLEOTIDE AND AMINO ACID SEQUENCES AND METHODS OF USE THEREOF FOR DIAGNOSIS - Novel splice variants, amino acid sequences and nucleotide sequences thereof, and methods of using same. | 2009-12-24 |
20090317809 | PROBE, PROBE SET, PROBE-IMMOBILIZED CARRIER, AND GENETIC TESTING METHOD - A nucleic acid probe for classification of pathogenic bacterial species is capable of collectively detecting bacterial strains of the same species and differentially detecting them from other bacterial species. Any one of the base sequences of SEQ ID NOS. 52 to 54 or a combination of at least two of them is used for detecting the gene of an infectious disease pathogenic bacterium. | 2009-12-24 |
20090317810 | METHODS AND NUCLEIC ACIDS FOR THE DETECTION OF COLORECTAL CELL PROLIFERATIVE DISORDERS - The invention provides methods, nucleic acids and kits for detecting, or for distinguishing between or among colorectal cell proliferative disorders. The invention discloses genomic sequences the methylation patterns of which have utility for the improved detection of and differentiation between said class of disorders, thereby enabling the improved diagnosis and treatment of patients. | 2009-12-24 |
20090317811 | TWO PORE CHANNELS AS REGULATORS OF PROLIFERATION IN CANCER - The present invention relates to the discovery that two pore K+ channel (2PK) gene expression is increased in tumors and tumor cell lines, especially prostate tumor cells. The present invention encompasses methods for disease diagnosis, drug screening and the treatment of cancer. | 2009-12-24 |
20090317812 | METHOD OF DETECTING PREECLAMPSIA - The invention provides a method for detecting a propensity toward or risk of developing preeclampsia, comprising detecting in a female subject the presence of a single base pair point mutation, ΔA at position +1754, in the HLA-G mRNA 3′UTR. The mutation is associated with preeclampsic subjects, and with decreased RNA stability in vitro. The presence of this ΔA mutation may provide an explanation for lower levels of HLA-G expression seen in association with preeclampsia. | 2009-12-24 |
20090317813 | METHOD OF PREDICTING METASTASIS OF ORAL CAVITY CANCER INTO CERVICAL LYMPH NODE AND DIAGNOSIS KIT TO BE USED IN THE PREDICTION - A method for objectively predicting possibility of metastasis to a cervical lymph node in an early stage for an individual case diagnosed as an oral cavity cancer, and a diagnosis kit to be used in the prediction are provided. The method includes a step of assaying expression amounts of metastasis prediction genes in which the expression amounts are changed between a metastasis group and a non-metastasis group, with respect to a sample collected from a primary legion of the oral cavity cancer. Further, the method includes a step of predicting the possibility of the metastasis by comparing the expression amounts of the metastasis gene group with the expression amounts of the metastasis prediction genes in a metastasis group and/or a non-metastasis group. Herein, the metastasis prediction gene group includes two genes MSR1 (NM_138716.1) and RET (M31213.1). | 2009-12-24 |
20090317814 | Mitochondrion-bound nucleic acid for determining a health status of an individual - The invention describes means and methods for determining mitochondrion-bound nucleic acid and describes the use thereof in diagnostics. Preferable cell-free mitochondrion-bound nucleic acid is determined. | 2009-12-24 |
20090317815 | Mononucleotide repeats microsatellite markers for detecting microsatellite instability - A method for evaluating microsatellite instability associated with a tumour, which entails the steps of amplifying microsatellite loci in a biological sample containing genomic DNA from the tumour and determining sizes of DNA amplification products, wherein at least one microsatellite locus selected from the group consisting of NR 21, NR 22, NR 24 and NR 27, is amplified. | 2009-12-24 |
20090317816 | METHODS FOR IDENTIFYING RISK OF BREAST CANCER AND TREATMENTS THEREOF - Provided herein are methods for identifying risk of breast cancer in a subject and/or a subject at risk of breast cancer, reagents and kits for carrying out the methods, methods for identifying candidate therapeutics for treating breast cancer, and therapeutic methods for treating breast cancer in a subject. These embodiments are based upon an analysis of polymorphic variations in nucleotide sequences within the human genome. | 2009-12-24 |
20090317817 | NUCLEIC ACID-BASED TESTS FOR PRENATAL GENDER DETERMINATION - Provided herein are compositions, processes and kits for noninvasive, early determination of fetal sex from, and/or amount of fetal nucleic acid in, an extracellular nucleic acid sample from a pregnant female. Such compositions, processes and kits are useful for detection of low genomic copy numbers of male fetal nucleic acid in a high copy number background of female nucleic acid, thereby determining the sex of a fetus and/or amount of fetal nucleic acid in a sample. | 2009-12-24 |
20090317818 | RESTRICTION ENDONUCLEASE ENHANCED POLYMORPHIC SEQUENCE DETECTION - Provided in part herein is an improved method for the detection of specific polymorphic alleles in a mixed DNA population. The method comprises enriching the relative percentage of a given polymorphic allele that is exponentially amplifiable by PCR. Provided also are methods for selectively enriching target nucleic acid, for example, fetal nucleic acid in a maternal sample. In the case of detecting fetal nucleic acid in a maternal sample, a restriction enzyme is introduced that can discriminate between the alleles of a polymorphic site. In some embodiments, the maternal allele is digested and nucleic acid comprising the paternal allele is relatively enriched. | 2009-12-24 |
20090317819 | PHOSPHOLIPID OXIDATION AND Lp-PLA2 AS PREDICTORS OF CORONARY ARTERY DISEASE - Provided herein are compositions and methods for identifying individuals at risk for developing coronary artery disease (CAD). | 2009-12-24 |
20090317820 | MICRO-RNA PROFILE IN HUMAN SALIVA AND ITS USE FOR DETECTION OF ORAL CANCER - The present invention provides for the first time the detection of micro-RNA in human saliva and the correlation between such micro-RNA and oral cancers. The present invention therefore provides methods and kits for diagnosing oral cancers by examining pertinent micro-RNA in saliva. | 2009-12-24 |
20090317821 | METHODS AND COMPOSITIONS FOR IDENTIFYING INDIVIDUALS AT REDUCED RISK OF SEPSIS - The present invention provides a method of identifying a subject having a reduced risk of developing sepsis, comprising detecting at least one APOE3 allele in nucleic acid from the subject. | 2009-12-24 |
20090317822 | SELECTION OF INTRACELLULAR IMMUNOGLOBULINS - A general immunoglobulin-target assay system is provided, in which a positive outcome (the generation of a signal) depends only on the intracellular interaction of immunoglobulin with target. This can be accomplished for many immunoglobulins expressed in yeast and/or in mammalian cells and allows the selection of immunoglobulins which are capable of functioning in an intracellular environment. | 2009-12-24 |
20090317823 | MUTATIONS IN CAPILLARY MORPHOGENESIS GENE-2 (CMG-2) AND USE THEREOF - Mutations and polymorphisms in a particular gene, the capillary morphogenesis gene-2 (CMG-2) have been identified. The mutations have been associated with infantile systemic hyalinosis (ISH) and juvenile hyaline fibromatosis (JHF), as well as conditions associated with these disorders. Described herein are variant CMG-2 nucleic acids and variant CMG-2 polypeptides; cells comprising such variant CMG-2 nucleic acids and/or expressing variant CMG-2 polypeptides; and methods of diagnosing and treating such disorders and conditions. Variant CMG-2 proteins include those comprising one or more of E220X, G105D, L329, P257insC, I189T, A357P, and A322S. Variant CMG-2 nucleic acids include those encoding these mutant CMG-2 proteins, as well as silent mutations or polymorphisms. | 2009-12-24 |
20090317824 | Fluid Processing Device Comprising Radial Channels - The present invention provides, in one aspect, an apparatus that comprises a disc-shaped substrate defining (1) a central reservoir region, (2) a plurality of channels in fluid communication with, and emanating substantially radially from, the central reservoir region, the channels being coplanar with each other, and each channel having (i) a proximal end which is linked to the reservoir region, and (ii) a distal end, and preferably (3) for each channel, at least one chamber, and preferably three chambers, linked by a passageway in fluid communication with the distal end of that channel. Preferably, each passageway leads from each chamber in a direction that is initially away from the central reservoir region, whereby centrifugation of the substrate about a central axis that is perpendicular to the channels is effective to disperse liquid from the central reservoir region into the channels and chambers, such that any air bubbles in the chambers, channels, and passageways are forced towards the axis of rotation, when such liquid is present in the central reservoir region. | 2009-12-24 |
20090317825 | ASSAY FOR PARKINSON'S DISEASE THERAPEUTICS AND ENZYMATICALLY ACTIVE PARKIN PREPARATIONS USEFUL THEREIN - The invention provides to assays for agent useful for treatment of Parkinson's Disease. Included are cell-based assays for agents that modulate the effect of Parkin proteins on proteasome function. The invention also provides recombinant, enzymatically active, Parkin protein produced in prokaryotic expression systems, such as | 2009-12-24 |
20090317826 | MONOCLONAL ANTIBODIES AND METHODS FOR THEIR USE IN THE DETECTION OF CERVICAL DISEASE - Compositions and methods for diagnosing high-grade cervical disease in a patient sample are provided. The compositions include novel monoclonal antibodies, and variants and fragments thereof, that specifically bind to MCM2. Monoclonal antibodies having the binding characteristics of an MCM2 antibody of the invention are further provided. Hybridoma cell lines that produce an MCM2 monoclonal antibody of the invention are also disclosed herein. The compositions find use in practicing methods for diagnosing high-grade cervical disease comprising detecting overexpression of MCM2 in a cervical sample from a patient. Kits for practicing the methods of the invention are further provided. Polypeptides comprising the amino acid sequence for an MCM2 epitope and methods of using these polypeptides in the production of antibodies are also encompassed by the present invention. | 2009-12-24 |
20090317827 | Receptor In Dendritic Cells - The present invention provides the use of GPR91 as a target in dendritic cells. | 2009-12-24 |
20090317828 | Diagnostic Kits to Detect SP22 and SP22 Antibodies - Oral, topical and injectable contraceptives, which are based on sperm protein 22 kDa (SP22) polypeptides and antibodies and infertility diagnostics and kits are provided. | 2009-12-24 |
20090317829 | High-throughput assay for sugar-mediated drug transport - The invention provides a rapid, quantitative assay to directly assess the impact of a diverse range of sugars upon the sugar-mediated uptake of corresponding sugar-conjugates into various cell types. | 2009-12-24 |
20090317830 | HEPATITIS C VIRUS NS2/3 ASSAY - The present invention provides an assay for the detection of the NS2/3 cleavage products NS2 or NS3 in the presence of uncleaved NS2/3. Following self-cleavage of NS2/3 to generate NS2 and NS3 cleavage products, a sample is incubated with a ligand specific for the recognition of NS2 or NS3 cleavage product in the presence of uncleaved NS2/3. There is provided a method for detecting a NS2/3 autocleavage product in a sample containing NS2/3 protease, whereby the amount of bound ligand detected correlates with the NS2/3 autocleavage activity. A further aspect of the present invention concerns ligands selectively recognizing one of the NS2 cleavage product or the NS3 cleavage product with minimal cross-reactivity with the uncleaved NS2/3 and the other cleaved product. The present invention provides antibodies that selectively recognize one of cleaved NS2 product or cleaved NS3 product with minimal cross-reactivity with the uncleaved NS2/3 and the other cleaved product. | 2009-12-24 |
20090317831 | Sepsis Test - There is provided a method for determining whether a subject has a bacterial infection comprising: identifying an abnormal expression of one or more of CD49e, CD 14, CD11c, CD49f, and CD29 on leucocytes in a sample obtained from the subject; wherein an abnormal expression of CD49e, CD 14, CD11c, CD49f or CD29 is indicative of the subject having a bacterial infection. | 2009-12-24 |
20090317832 | Cell Classification System - The present invention involves the reaction of a CD4 immuno-conjugate with a sample of patient whole blood. The CD4 immuno-conjugate consists of one or more antibodies with specificity for the CD4 surface receptor coupled to a signal moiety, or “label”, that is detectable by a flow cytometer. Such labels may generate a signal by such means as fluorescence properties, light scatter properties, electronic properties, or magnetic properties. The CD4 immuno-conjugate binds to both the CD4 positive lymphocytes (Helper T cells) and all monocytes. Differential detection means are employed to count immuno-conjugate labeled Helper T cells. The present invention distinguishes itself by simultaneously measuring the signal level from monocytes as a means to verify sufficient activity of the anti-CD4 antibody. | 2009-12-24 |
20090317833 | Screening Method - The present invention provides a method of screening for a drug for the prophylaxis or treatment of at least one disease selected from the group consisting of cardiac disease, autoimmune disease, inflammatory disease, central nervous system disease, infectious disease, sepsis, severe sepsis and septic shock, which includes selecting a substance that binds to an intracellular region of TLR4, and inhibits signal transduction from said molecule, and a kit for this method, which contains (1) a cell that expresses wild-type TLR4 and (2) a cell that expresses a mutant TLR4, and which can detect a signal from TLR4 with expression of a reporter gene as an index. | 2009-12-24 |
20090317834 | NOVEL CELLULAR GLYCAN COMPOSITIONS - The invention describes novel compositions of glycans, glycomes, from human embryonic stem cells, and especially novel subcompositions of the glycomes with specific monosaccharide compositions and glycan structures. The invention is further directed to methods for modifying the glycomes and analysis of the glycomes and the modified glycomes. Furthermore, the invention is directed to stem cells carrying the modified glycomes on their surfaces. The glycomes are preferably analysed by profiling methods able to detect reproducibly and quantitatively numerous individual glycan structures at the same time. The most preferred type of the profile is a mass spectrometric profile. The invention specifically revealed novel target structures and is especially directed to the development of reagents recognizing the structures. | 2009-12-24 |
20090317835 | DEVICE FOR SAMPLING CELLS BY CONTACT - A microtechnological device ( | 2009-12-24 |
20090317836 | Methods for Detection of Circulating Tumor Cells and Methods of Diagnosis of Cancer in Mammalian Subject - Methods are provided for detecting circulating tumor cells in a mammalian subject. Methods of diagnosing cancer in a mammalian subject are provided. The methods of detection or diagnosis indicate the presence of metastatic cancer or early stage cancer. | 2009-12-24 |
20090317837 | CANCER DIAGNOSIS BASED ON LEVELS OF ANTIBODIES AGAINST GLOBO H AND ITS FRAGMENTS - A cancer diagnostic method using a glycan array that contains Gb5 and Globo H, Bb2, Bb3, and/or Bb4. | 2009-12-24 |
20090317838 | DETECTION OF BACTERIAL PEPTIDOGLYCAN-LIKE COMPOUNDS - Innate immunity to bacterial pathogens relies on the detection of bacterial peptidoglycans. Intracellular NOD2 proteins sense peptidoglycans and respond by activating transcription factors. An in vitro assay utilizing a reporter gene under the control of a promoter that contains transcription recognition sequences for the binding of a transcription factor that is activated by NOD2 in cells transfected to express NOD2 or NOD2 and TLR2 can identify bacterial infection or sepsis by detecting bacterial peptidoglycans. | 2009-12-24 |
20090317839 | BOTULINUM TOXIN SCREENING ASSAYS - Methods for detecting BoNT/A activity in a sample, methods for screening molecules able to compete with BoNT/A receptor binding, methods for reducing BoNT/A activity in a human and methods of marketing a neurotoxin capable of selectively binding to FGFR3 to a governmental or regional regulatory authority. | 2009-12-24 |
20090317840 | AUTOMATED DETERMINATION OF CHLAMYDIA INFECTION-FORMING UNITS - The present features an automated method of measuring | 2009-12-24 |
20090317841 | Methods and Materials for the Detection of Leishmania Infection - The present invention provides rapid diagnostic assays for the detection of | 2009-12-24 |