51st week of 2008 patent applcation highlights part 46 |
Patent application number | Title | Published |
20080312059 | Folding apparatus - A folding apparatus includes a feed unit for supplying a medium to be folded, a folding substrate forming a convexly curved support surface for the medium and adapted to be driven back and forth in a circumferential direction of the curved support surface, and a pinch and guide structure for folding and guiding the medium on the support surface. The pinch and guide structure includes at least one endless belt that is arranged to have a belt portion held in mating engagement with a portion of the curved support surface. | 2008-12-18 |
20080312060 | Screw-Type Solid Bowl Centrifuge - A screw-type solid-bowl centrifuge including a rotatable drum having a tapering portion and a cylindrical portion. The rotatable screw includes a screw body, at least one main screw blade surrounding the screw body and forming a plurality of screw flights. The plurality of screw flights forms a conveying path configured to transport a material to be processed in the centrifuge. Two blade segments are arranged in the conveying path in portions of the plurality of screw flights. The at least one main screw blade is provided in a region of the blade segments that includes clearances configured to allow a throughflow of the material to be processed to flow between adjacent screw flights. | 2008-12-18 |
20080312061 | Pellets for Se Encapsulation - Pellets encapsulating selenium or a compound of selenium comprise one hollow cavity filled with the selenium surrounded by a matrix which is able to form an eutectic with at least one of the constituents of a batch of molten raw materials for the manufacture of glass. | 2008-12-18 |
20080312062 | OPTICAL GLASS AND LENS - The invention provides an optical glass comprising, by mass % on the oxide basis; 25 to 50% of B | 2008-12-18 |
20080312063 | OPTICAL GLASS - The present invention provides an optical glass including, by mass %: 46 to 70 of B | 2008-12-18 |
20080312064 | Porous, Fired Ceramic Foam - The invention relates to a porous, fired ceramic foam having a total porosity of between 50 and 92% and an intergranular porosity of at least 5%. In particular, the invention relates to a recrystallised silicon carbide foam. | 2008-12-18 |
20080312065 | Highly Filled Dispersions Containing Aluminium Oxide - Aqueous dispersion containing:
| 2008-12-18 |
20080312066 | Message energy memory ceramics - The present invention provides a message energy memory ceramics. The message information memory ceramics includes: (1) a plurality of message energy memory ceramics grains composed of a silicon oxide, an aluminum oxide, a sodium oxide, a potassium oxide, a magnesium oxide, a calcium oxide, a titanium oxide, an ferric oxide, a manganese oxide, and a zinc oxide; and (2) a powder of message energy memory ceramics grains composed of a silicon oxide, an aluminum oxide, a sodium oxide, a potassium oxide, a magnesium oxide, a calcium oxide, a titanium oxide, an ferric oxide, a manganese oxide, and a zinc oxide. The products of the present invention can be applied to general water supply stations, water towers, and drinking water machines. | 2008-12-18 |
20080312067 | Highly Filled Dispersion Containing Transition Aluminium Oxide - Aqueous dispersion containing transition aluminium oxide as only solid and a dispersant, in which—the transition aluminium oxide is present in the form of aggregates of primary particles, the content of transition aluminium oxide in the dispersion is from 40 to 65% by weight, the aggregates in the dispersion have a mean aggregate diameter of less than 100 nm,—the dispersant contains polyaluminium hydroxychloride, polyaluminium hydroxynitrate and/or polyaluminium hydroxysulphate, the dispersion has a pH of from 3 to 5. | 2008-12-18 |
20080312068 | Nano-sized palladium-doped anion exchange resin catalyst or palladium-doped cation exchange resin catalyst, preparation method thereof and method of removing dissolved oxygen in water using the same - Disclosed are a nano-sized palladium-doped anion exchange resin catalyst or palladium-doped cation exchange resin catalyst, a preparation method thereof and a method of removing dissolved oxygen in water using the same. The palladium-doped anion exchange resin catalyst exhibits high dissolved oxygen removal efficiency of 99˜99.99%, and the palladium-doped cation exchange resin catalyst exhibits high dissolved oxygen removal efficiency of at least 97%, and further, dissolved oxygen in water can be removed through a catalytic reaction without the use of additional chemicals, thereby discharging no secondary pollutants. This catalyst is environmentally friendly, can be continuously developed, and can prevent the loss of the palladium catalyst, which is expensive, and thus can be efficiently applied to various fields, including semiconductors, power plants, microbial culture, food and pharmaceutical production, and the fermentation industry. | 2008-12-18 |
20080312069 | REGENERATION OF CATALYSTS FOR DESTRUCTION OF ORGANOPHOSPHONATE COMPOUNDS - Volatile organic compounds, for example organophosphonate compounds including chemical warfare agents, pesticides, and solvents, are decomposed by contacting the compounds with either a manganese oxide catalyst in the presence of visible light or a catalyst material selected from the group consisting of vanadium, vanadium oxide, manganese oxide and mixtures thereof deposited upon a catalyst support that is heated to at least 300 C. The catalyst material may be regenerated by a process selected from the washing with water, washing with a solvent, heating, exposing to light, purging with oxygen, purging with a reactive gas, exposing to microwave radiation, and combinations thereof. The catalyst composition may be used as an air filter in a vehicle, a building or a personnel protection device, such as a gas mask. | 2008-12-18 |
20080312070 | Method for Making a Material - The invention relates to a method for forming a material of a metal oxide supported on a support particle by the steps of. a) providing a precursor mixture comprising a solution containing one or more metal cations and (i) a surfactant; or (ii) a hydrophilic polymer; with the precursor mixture further including support particles; and b) treating the precursor mixture from (a) above by heating to remove the surfactant or hydrophilic polymer and form metal oxide having nano-sized grains, wherein at least some of the metal oxide formed in step (b) is deposited on or supported by the support particles and the metal oxide has an oxide matrix that includes metal atoms derived solely from sources other than the support particles. | 2008-12-18 |
20080312071 | HOLDING AND SEALING MATERIAL FOR CATALYTIC CONVERTER AND METHOD OF MANUFACTURING THE HOLDING SEAL MATERIAL - A holding and sealing material for a catalytic converter for disposition between a cylindrical catalyst carrier and a metal shell covering the outer periphery of the catalyst carrier. The holding and sealing material includes a fiber aggregate mainly formed of alumina-silica based ceramic fibers having a mullite crystal content of 10 wt % or less, and the fiber aggregate is subjected to a needle punch treatment. Owing to the improved holding and sealing material, a catalytic converter having excellent durability and assemblage and having extremely low pollution characteristics is provided. | 2008-12-18 |
20080312072 | Gas Sorbing Composite Systems And Methods For Their Manufacturing - A gas sorbing system is formed by gas sorbing components which are dispersed in a polymeric matrix which is porous or permeable to the gases to be sorbed. The gas sorbing components include a central nucleus, selected among a silica particle, polyhedral oligomeric silsesquioxane and a spherosilicate, to which there are bound at least one organic or metalorganic radical carrying a functional group, which is able to chemically fix the gas to be sorbed, and at least one anchoring organic radical including a chain of carbon atoms, which has the functionality of fixing the nucleus in the matrix polymer. | 2008-12-18 |
20080312073 | Self Supporting Structurally Engineered Non-Platinum Electrocatalyst for Oxygen Reduction in Fuel Cells - A highly dispersed, unsupported, electrocatalyst made of pyrolyzed porphyries and a method for synthesizing the same. The disclosed synthesis procedure allows for optimization of pore size and therefore transport properties. Compounds suitable for use include transition metal N | 2008-12-18 |
20080312074 | Hydrotreating catalyst sulphiding agent and its use for in situ and ex situ presulphidation - The present invention relates to a sulphiding agent for a hydrotreating catalyst which makes possible faster sulphiding of the catalyst but which also makes possible to very significantly limit solid deposits, in particular of sulphur. | 2008-12-18 |
20080312075 | ZIRCONIA POROUS BODY AND MANUFACTURING METHOD THEREOF - A zirconia porous body with excellent stability of heat resistance is manufactured. This relates to a zirconia porous body having peaks at pore diameters of 8 to 20 nm and 30 to 100 nm in a pore distribution based on the BJH method, with a total pore volume of 0.4 cc/g or more, and to a zirconia porous body having a peak at a pore diameters of 20 to 110 nm in a pore distribution based on the BJH method, with a total pore volume of 0.4 cc/g or more. | 2008-12-18 |
20080312076 | Process for sulfurization or presulfurization of solid particles of a catalyst or an adsorbent - The invention relates to a process for incorporating sulfur in the porosity of the solid particles of a catalyst for the conversion of hydrocarbons or an adsorbent. This process is carried out off-site in the presence of hydrogen sulfide that is pure or diluted in hydrogen or nitrogen, a process in which said particles are made to rise or fall in a sulfur incorporation zone that comprises at least one vibratory helical coil that is essentially tubular in shape and that comprises at least two turns, whereby said particles are subjected to a temperature profile over the majority of their path in said coil and whereby said particles are brought into contact with at least one fluid on at least one portion of their path. | 2008-12-18 |
20080312077 | Method for image formation and intermediate transfer recording medium - The present invention provides a method for image formation, that can yield thermally transferred images which are excellent in various fastness properties even under severe service conditions, and an intermediate transfer recording medium for use in the method for image formation. The method for image formation comprises the steps of: providing an intermediate transfer recording medium comprising a substrate film and a transfer portion provided separably on the substrate film; forming an image on the intermediate transfer recording medium in its transfer portion; transferring the transfer portion onto an object; and, thereafter, again transferring the intermediate transfer recording medium in its next transfer portion once or more onto the object with the image formed thereon. In this case, in the intermediate transfer recording medium, a hologram image is set every at least second image plane, and an image can be formed on the transfer portion having the hologram image. This can offer an advantage that the transfer portion, with a thermally transferable image formed thereon, can be transferred onto an object followed by the superimposition of a transfer portion, to be served as the outermost surface in the final form onto the transferred portion once or more to provide a strong film for protecting the thermally transferred image. Thus, the problems of the prior art could have been solved. | 2008-12-18 |
20080312078 | 6-Phenyl-Pyrazolopyrimidine-7-Ylamine Fungicides - The invention relates to a 6-phenyl-pyrazolopyrimidine-7-ylamine of formula (I), wherein substituents are defined according to the description. Methods for producing said compounds, agents containing said compounds and the use thereof for controlling phytopathogenic parasitic fungi are also disclosed. | 2008-12-18 |
20080312079 | COLORANT FOR FOLIAGE OF HUMIC AND/OR FULVIC ACID, AND DYE - The invention relates to a colorant composition comprising humic acid and/or fulvic acid and a water soluble dye. The invention in particular relates to a colorant composition and method for imparting color to turf grass. | 2008-12-18 |
20080312080 | Novel dioctatin derivatives and production process thereof - To provide dioctatin derivatives, a production process thereof, an aflatoxin production inhibitor containing the dioctatin derivative, and a method of controlling aflatoxin contamination by use of the aflatoxin production inhibitor containing the dioctatin derivative. The present invention provides dioctatin derivatives represented by the following Structural Formula (I): | 2008-12-18 |
20080312081 | Method for Control of Ground Shoots of Vines and Other Trunk Vegetation - Protoporphyrinogen oxidase enzyme-inhibiting herbicides are useful in a method for controlling unwanted ground shoots of vines and other trunk vegetation. Of particular interest is the use of carfentrazone ethyl and certain metabolites thereof for control of unwanted ground shoots of vines and other trunk vegetation. | 2008-12-18 |
20080312082 | SOYBEAN EVENT DP-305423-1 AND COMPOSITIONS AND METHODS FOR THE IDENTIFICATION AND/OR DETECTION THEREOF - Compositions and methods related to transgenic high oleic acid/ALS inhibitor-tolerant soybean plants are provided. Specifically, the present invention provides soybean plants having a DP-305423-1 event which imparts a high oleic acid phenotype and tolerance to at least one ALS-inhibiting herbicide. The soybean plant harboring the DP-305423-1 event comprises genomic/transgene junctions having at least the polynucleotide sequence of SEQ ID NO:8, 9, 14, 15, 20, 21, 83 or 84. The characterization of the genomic insertion site of the DP-305423-1 event provides for an enhanced breeding efficiency and enables the use of molecular markers to track the transgene insert in the breeding populations and progeny thereof. Various methods and compositions for the identification, detection, and use of the soybean DP-305423-1 events are provided. | 2008-12-18 |
20080312083 | Herbicidal Composition Comprising and Aminophosphate or Aminophosphonate Salt and a Betaine - The present invention relates to herbicidal compositions comprising an aminophosphate or aminophosphonate salt, particularly to herbicidal compositions comprising a relatively high amount of aminophosphate or aminophosphonate salt and a betaine-based surfactant composition of mater. | 2008-12-18 |
20080312084 | DIFLUOROMETHANESFONYL ANILIDE DERIVATIVES USEFUL AS HERBICIDES - Novel difluoromethanesulfonamide derivatives of the formula (I) Difluoromethanesulfonamide derivatives represented by the formula | 2008-12-18 |
20080312085 | Pesticidal Compositions - The present invention relates to 1-(Azolin-2-yl)-amino-alkane compounds, which are useful for combating insects, arachnids and nematodes. | 2008-12-18 |
20080312086 | PEST CONTROL SHEET - A sheet for pest control, wherein said sheet is of polymeric material and comprises at least two layers; a top layer and a bottom layer, wherein the bottom layer contains a herbicide and one or more pesticides selected from among fungicides and insecticides, and the top layer optionally containing an insecticide and/or fungicide. Other aspects of the invention include a polymeric composition used in the preparation of the sheets and a method for pest control in agriculture, horticulture and gardens. | 2008-12-18 |
20080312087 | 2-Propenal and Related Enal Compounds for Controlling Plant Pests and Weeds in Soil - A method for controlling pests and weeds on or around plants, especially crop plants is disclosed. The method includes admixing 2-propenal or other related enal compounds to form an aqueous solution, and applying the aqueous solution to plants, plant seeds, weeds, or soil around the around the area in which the plants grow. | 2008-12-18 |
20080312088 | Field effect transistor, logic circuit including the same and methods of manufacturing the same - Provided are a field effect transistor, a logic circuit including the same and methods of manufacturing the same. The field effect transistor may include an ambipolar layer that includes a source region, a drain region, and a channel region between the source region and the drain region, wherein the source region, the drain region, and the channel region may be formed in a monolithic structure, a gate electrode on the channel region, and an insulating layer separating the gate electrode from the ambipolar layer, wherein the source region and the drain region have a width greater than that of the channel region in a second direction that crosses a first direction in which the source region and the drain region are connected to each other. | 2008-12-18 |
20080312089 | Superconducting Cable - A superconductive cable is provided which upon normal state, restricts flowing of electric current to a former to the maximum extent to thereby keep a cryogenic state in the superconductive cable stable. The superconductive cable includes a former surrounded by a superconductive layer and a cryostat provided at the outside of the superconductive layer, wherein the former includes a metal wire-wound part around which a plurality of wires is wound and an eddy-current prevention layer provided on the outer face of the wire-wound part, and the metal wires and the eddy-current prevention layer are made of a copper alloy. | 2008-12-18 |
20080312090 | Combinatorial Processing Including Stirring - Combinatorial processing including stirring is described, including defining multiple regions of a substrate, processing the multiple regions of the substrate in a combinatorial manner, introducing a fluid into a first aperture at a first end of a body to dispense the fluid out of a second aperture at a second end of the body and into one of the multiple regions, and agitating the fluid using an impeller at a second end of the body to facilitate interaction of the fluid with a surface of the substrate. | 2008-12-18 |
20080312091 | INVERTEBRATE ACETYLCHOLINESTERASE INHIBITORS - Methods for determining invertebrate- and insect-specific, such as mosquito-specific, residues of acetylcholinesterases are provided herein. The methods can be used to design pesticides and insecticides that are specific for the invertebrate or insect (e.g., mosquito) enzymes, resulting in reduced toxicity concerns for mammals. Compositions for inhibiting invertebrate and insect (e.g., mosquito) acetylcholinesterases and methods for preparing the same are also provided. | 2008-12-18 |
20080312092 | Photoinduced Signal Amplification Through Externally Sensitized Photofragmentation in Masked Photosensitizers - A method of photochemically amplifying the chemical signal associated with unmasking a photosensitizer and releasing a radical leaving group when a photochemical chain reaction is initiated by a sensitizer attached to a molecule of interest is provided. More specifically, provided is a method of photoinduced amplification comprising: providing a plurality of masked photosensitizers, each masked photosensitizer having a masking group bonded to a photosensitizer through a releasable covalent bond which disrupts the conjugation of the photosensitizer; providing a reaction photosensitizer in releasing proximity to a first masked photosensitizer; exciting the reaction photosensitizer with photoradiation, whereby the reaction photosensitizer induces release of the masking group from the first masked photosensitizer, producing a first unmasked photosensitizer which induces release of the masking group from a second masked photosensitizer in releasing proximity to the first masked photosensitizer, and so on. The release of the masking group from masked photosensitizer continues as long as masked photosensitizers are in releasing proximity to the reaction photosensitizer, or until a side reaction occurs which stops the chain propagation, or until the source of light is turned off. | 2008-12-18 |
20080312093 | Method for detecting cancer and a method for suppressing cancer - An object of the invention is to find a cancer-associated gene to be used as an index for detecting canceration of cells and degree of malignancy of cancer, so as to provide a method for detecting cancer using the cancer-associated gene as an index and provide a method of suppressing/treating cancer using the cancer-associated gene as essential part. According to the present invention, specific genes which are amplified or deleted in gastric carcinoma as compared with normal cell have been collectively found, and a method for detecting cancer using amplification or deletion of these cancer-associated genes as an index is provided. Further, cancer can be suppressed by introducing a gene which is deleted in cancer cells among these cancer-associated genes into cancer and inhibiting the transcription product of the gene amplified. | 2008-12-18 |
20080312094 | MUTATED AQP, METHOD FOR DETECTING CANCER USING THE SAME, DNA CHIP HAVING OLIGONUCLEOTIDES OF SAID MUTATED AQP SEQUENCE - The present invention relates to mutation genes of the AQP (aquaporin), a method for detecting cancer using mutations and expressions of the AQP and a DNA chip possessing oligonucleotides of mutated AQP base sequence. In case of the present method for detecting cancer and DNA chip using the AQP's mutations and expressions, it is highly accurate, rapid and effective in cancer diagnosis. | 2008-12-18 |
20080312095 | VACCINE DESIGN METHODOLOGY - Systems and methodologies for efficient vaccine design are disclosed herein. A methodology for efficient vaccine design in accordance with one or more embodiments disclosed herein may be operable to receive a graph having vertices corresponding to epitope sequences present in the pathogen population, weights for respective vertices corresponding to respective frequencies with which corresponding epitope sequences appear in the pathogen population, and directed edges that connect vertices that correspond to overlapping epitope sequences. Such a methodology may also be operable to determine a candidate vaccine sequence of overlapping epitope sequences by identifying a path though the graph corresponding to a series of connected vertices and directed edges that maximizes the total weight of the vertices in the path for a desired vaccine sequence length. | 2008-12-18 |
20080312096 | Predictive and Therapeutic Markers in Ovarian Cancer - Cancer markers may be developed to detect diseases characterized by increased expression of apoptosis-suppressing genes, such as aggressive cancers. Genes in the human chromosomal regions, 8q24, 11q13, 20q11-q13, were found to be amplified indicating in vivo drug resistance in diseases such as ovarian cancer. Diagnosis and assessment of amplification levels certain genes shown to be amplified, including PVT1, can be useful in prediction of poor outcome of patient's response and drug resistance in ovarian cancer patients with low survival rates. Certain genes were found to be high priority therapeutic targets by the identification of recurrent aberrations involving genome sequence, copy number and/or gene expression are associated with reduced survival duration in certain diseases and cancers, specifically ovarian cancer. Therapeutics to inhibit amplification and inhibitors of one of these genes, PVT1, target drug resistance in ovarian cancer patients with low survival rates is described. | 2008-12-18 |
20080312097 | Immunological assay and chip - The present invention provides an immunological assay suitable to be carried out on a chip. After an antigen-antibody complex in which an antigen | 2008-12-18 |
20080312098 | Use of a Gip Promoter Polymorphism - The use of the single nucleotide polymorphism (SNP) at position −(97) of the GIP gene for the identification of a cardiovascular disease or of an increased risk for developing a cardiovascular disease in a biological sample taken from an individual to be examined. | 2008-12-18 |
20080312099 | Microarray, System, and Method for Detecting, Identifying, and Quantitating Micro-Rnas - Micro-RNA (miRNA) microarrays useful for detecting, identifying and quantitating miRNAs in a sample include oligonucleotide probes that specifically bind miRNAs. Exemplary miRNA microarray can be specific for miRNAs of human, canine, mouse, rat, or another species. | 2008-12-18 |
20080312100 | Hybridization Method as Well as Hybridization Microarray and Hybridization Kit - A method of simply and reliably hybridizing a sample biopolymer using a glass coverslip and a closed vessel by hybridizing the sample biopolymer and a probe biopolymer with each other in a state that a solution containing the sample biopolymer is in contact with only a slide glass to which the probe biopolymer is immobilized in a closed vessel containing a solution having the same vapor pressure as the solution containing the sample biopolymer is provided. A microarray and a kit for hybridization employed for the present invention are also provided. | 2008-12-18 |
20080312101 | Novel Phage Display Technologies - The present invention provides novel technologies for producing and screening fusion proteins on the surface of filamentous phage. In particular, a single vector can be used for generating cell and phage libraries containing a given series of protein sequences fused to either one or other of two phage coat proteins. This approach simplifies and improves the efficiency of the subsequent phage display-based selection of protein-binding molecules having therapeutic or diagnostic utility, such as antibodies, peptides, or epitope-binding regions. | 2008-12-18 |
20080312102 | Cytokine Binding Domains - The present invention relates a method of generating modified binding moieties comprising a cytokine binding domain consisting of a first FmIII-like domain and a second FnIII-like domain in which at least one amino acid residue within the cytokine binding domain in modified such that the binding characteristics of the cytokine binding domain are altered, and/or, the solubility and/or stability of the binding moiety is improved. The invention also relates to binding moieties and to the use of such binding moieties as affinity reagents, diagnostic reagents, therapeutic agents and protein scaffolds | 2008-12-18 |
20080312103 | Linker For Constructing Mrna-Puromycin-Protein Conjugate - The present invention provides a linker preferably used when constructing an mRNA/cDNA-puromycin-protein conjugate used in an in vitro virus method, and an mRNA/cDNA-puromycin-protein conjugate constructed using that linker. More specifically, the present invention provides a linker for ligating mRNA and puromycin or a puromycin-like compound to construct an mRNA/cDNA-puromycin-protein conjugate, the linker comprising a single-stranded RNA as a main backbone, and having, in this main backbone, a solid phase binding site for binding an mRNA-puromycin-protein conjugate to a solid phase site, and a pair of cleavage sites provided at locations surrounding the solid phase binding site; an mRNA-puromycin-protein conjugate constructed using this linker; an mRNA bead or an mRNA chip comprising this conjugate; a protein chip produced from this mRNA chip; and a diagnostic kit using the mRNA bead or the mRNA chip. | 2008-12-18 |
20080312104 | BIOLOGICAL MATERIAL PREPARATION CHIP AND PREPARATION CHIP SYSTEM - The present invention is directed to provide a preparation chip system having a simpler configuration and improved reliability while addressing the case where a plurality of reagents have to be fed as in a preparation of extracting DNA from a sample solution. The preparation chip system includes a sample chamber, a dissolving solution chamber, a cleaning solution chamber, an eluting solution chamber, a mixing passage connected to the sample chamber and the dissolving solution chamber and mixing the sample and the dissolving solution with each other, a carrier part connected to the mixing passage, a waste chamber connected to the carrier part via a holding passage, a collection chamber holding the eluting solution passed through the carrier part, and a plurality of resistive materials forming a passage resistor disposed in a first passage connecting the cleaning solution chamber with both the mixing passage and the carrier part. The eluting solution is passed through the carrier part by pressure from a pressure source. | 2008-12-18 |
20080312105 | Sensor For Biomolecules and a Method of Analysis Using Said Sensor - Disclosed is a method of preparing a sensor for the analysis of a sample fluid, said sample fluid containing one or more target molecules. The method comprises the step of introducing said sample fluid into a chamber equipped with a porous substrate, one or more probe molecules being applied to said porous substrate and said probes being able to specifically bind to said one or more target molecules. The method further comprises the step of moving said substrate and said chamber relatively to each other in order to force said sample fluid through the pores of said porous substrate and to capture the one or more target molecules with the one or more probe molecules. Also disclosed is a sensor for the analysis of a sample fluid. | 2008-12-18 |
20080312106 | Substrate Material for Analyzing Fluids - The invention relates to a substrate material for analyzing fluids which has first areas with a high porosity and second areas with a lower porosity. | 2008-12-18 |
20080312107 | Process for treating underground formations - A process for disrupting filter cake in an underground formation, which includes (i) incorporating into a treatment fluid a solid polymer capable of being converted by hydrolysis into one or more organic acids; (ii) introducing the treatment fluid into the underground formation; and (iii) allowing the solid polymer to hydrolyze in the presence of water to produce organic acid such that acid soluble material within the filter cake or adjacent formation is dissolved. | 2008-12-18 |
20080312108 | Compositions and process for recovering subterranean oil using green non-toxic biodegradable strong alkali metal salts of polymerized weak acids - Compositions and process for recovering of oil from subterranean oil-bearing reservoirs consisting of green non-toxic biodegradable strong alkali metal salt of polymerized weak acids, one or more surfactants, an aqueous fluid, a optionally one or more mobility control agents and optionally one or more co-solvents are disclosed. Such compositions are injected into the reservoir through one or more injection wells and assist in recovering trapped oil through one or more producing wells. | 2008-12-18 |
20080312109 | Lubrication by Exposure to Light - The present invention concerns a method for a location and/or time-dependent alteration of the friction coefficient and/or adhesion force between two bodies, which includes irradiation of one or both contact surfaces between the bodies with radiation, use of the method according to the invention for location and/or time-dependent alteration of the friction coefficient and/or adhesion force between to bodies, a system that includes two bodies in which the friction coefficient and/or the adhesion force between the bodies can be temporarily or permanently altered, and a device for location and/or time-dependent regulation of the friction coefficient and/or adhesion force which includes the system according to the invention and a control unit. | 2008-12-18 |
20080312110 | GLYCOL-BASED MAGNETORHEOLOGICAL FLUIDS CONTAINING INORGANIC CLAYS, AND THEIR METHOD OF MANUFACTURE - A magnetorheological (MR) fluid comprising a glycol-based carrier fluid, a magnetizeable particle, and an inorganic clay. The MR fluid is particularly suitable for use in devices that have materials incompatible with typical hydrocarbon-based MR fluids, for example in devices where natural rubber is in contact with the fluids as in automotive engine mounts. The fluid is substantially non-foaming, and an improvement over glycol fluids thickened with organoclays. | 2008-12-18 |
20080312111 | Nanoparticle Compositions and Methods for Making and Using the Same - A composition that includes solid lubricant nanoparticles and an organic medium is disclosed. Also disclosed are nanoparticles that include layered materials. A method of producing a nanoparticle by milling layered materials is provided. Also disclosed is a method of making a lubricant, the method including milling layered materials to form nanoparticles and incorporating the nanoparticles into a base to form a lubricant. | 2008-12-18 |
20080312112 | Lubricating formulations for dispersancy and temperature, friction, and wear reduction - The present invention provides a working fluid additive for use in conjunction with a working fluid within an operating system having contact surfaces. The working fluid additive may consist solely of a highly polar material, but preferably includes both a highly polar material and a material that is synergistic to the highly polar material. The highly polar materials have a great affinity for the contact surfaces within the operating system and, therefore, produce film layers on the contact surfaces sufficient to significantly eliminate the frictional losses experience in the boundary regime of lubrication. By including a synergistic polar material, the efficacy as well as the thickness of this film layer is increased to further increase friction reduction. Organo-metallics may be utilized to further decrease wear and friction. An enhancing accelerator may be used to increase the compatibility between the host working fluid and the additive. A dispersion agent may also be employed within to disperse the working fluid additive within the working fluid. | 2008-12-18 |
20080312113 | Food Grade Lubricant Compositions - Novel non-aqueous water soluble food grade lubricant compositions comprising: (a) About 5% to about 50% of a polyalkylene glycol comprised of an ethylene oxide/propylene oxide copolymer, or polymer of propylene oxide, having molecular weight greater than 1,500; and (b) About 50% to about 95% of a polyethylene glycol having molecular weight of from about 200 to about 600; wherein said lubricating compositions have viscosities of about 28 to about 100% at 40° C. The novel non-aqueous water soluble food grade lubricant compositions are particularly useful in food processing and packaging equipment applications where low viscosity food grade lubricants with low pour points are desired, and in applications where there is a need for equipment and spill cleanup. These food grade lubricant compositions are also environmentally friendly due to their water solubility, rapid biodegradability, and low aquatic toxicity. | 2008-12-18 |
20080312114 | Composition and Methods for Improved Lubrication, Pour Point, and Fuel Performance - An additive includes polyalphaolefin (PAO), a calcium source, and one or more oils from, or components derived from, beans, seeds, or roots, such as castor oil, jojoba oil, rape (canola) seed oil, palm oil, sunflower oil, soybean oil, etc. The preferred composition of matter comprises a calcium source, PAO, castor oil, jojoba oil, and a soy methyl ester and/or rape seed methyl or ethyl ester. The additive may be used in fuels that improve combustion engine performance in terms of efficiency and emissions. The additive may be used in lubricants that improve performance of both ferrous and non-ferrous metal components of engines, guns, or other machinery. The additive also may be used in cutting fluids for machining and fabrication. Used in conjunction with other additives, embodiments of the invention may be used, to lower pour points in oils, esters and other similar products. | 2008-12-18 |
20080312115 | Antiwear Lubricant Compositions for Use in Combustion Engines - The invention relates to an additive composition, which comprises an additive mixture that essentially consists of a) At least one ammonium phosphate ester; b) At least one thiophosphoric acid ester, and c) At least one dithiophosphoric acid derivative; in combination with sulphur containing oil additives; and a process for the reduction of wear in combustion engines, such as spark ignition or Diesel motor engines. | 2008-12-18 |
20080312116 | Multifunctional Lubricant Additive Package - The present invention provides a multifunctional lubricant additive package or composition for improving load-carrying capacity, scuffing (scoring) resistance, and other performance characteristics of a lubricant. The composition includes a molybdenum compound, a secondary zinc dithiophosphate compound, an aryl or alkyl phosphite compound, and a compound having an alkylthiocarbamoyl group. The present invention further provides a method for improving the performance characteristics of a lubricant. The method includes mixing a lubricant base stock or a fully-formulated lubricant with the above-described multifunctional lubricant additive composition. | 2008-12-18 |
20080312117 | High Viscosity Lubricant Copolymers - A copolymer suitable for the use in or as a lubricant, which copolymer includes an α-olefin and a di-ester of an α,β ethylenically unsaturated dicarboxylic acid. More particularly, a high molecular weight lubricating oil base fluid or additive includes a copolymer of α-olefins with chain lengths, for example from 12 to 18 carbon atoms, and a di-ester of an α,β ethylenically unsaturated dicarboxylic acid, with a C | 2008-12-18 |
20080312118 | HARD SURFACE CLEANING COMPOSITION WITH HYDROPHILIZING AGENT AND METHOD FOR CLEANING HARD SURFACES - A composition for cleaning or rinsing hard surfaces in an aqueous or aqueous/alcoholic medium including at least one organophosphorus material for contributing to said surfaces antideposition and/or antiadhesion properties with regard to soiling substances capable of being deposited on the surfaces. | 2008-12-18 |
20080312119 | Hard surface cleaning compositions comprising certain perfluroalkyl substituted compounds - This invention relates to hard surface cleaning compositions comprising certain perfluoroalkyl-substituted compounds. More particularly, it relates to novel compositions comprising perfluoroalkyl-substituted compounds which are the reaction products of a mono-, di- or polyamine of 60 to 10,000 molecular weight with a perfluoroalkyl-substituted unsaturated acid or its corresponding lower alkyl ester and optionally a non-fluorinated amino-reactive compound such as an acid, ester, anhydride, substituted epoxide, epichlorohydrin, isocyanate or urea. These compounds are useful as components of hard surface cleaning compositions. | 2008-12-18 |
20080312120 | DETERGENT COMPOSITION WITH HYDROPHILIZING SOIL-RELEASE AGENT AND METHODS FOR USING SAME - Laundry detergent compositions that provide soil release benefits to all fabric comprising an organophosphorus soil release agents and optional non-cotton secondary soil release agents. The present invention further relates to a method for providing soil release benefits to cotton fabric by contacting cotton articles with a water soluble and/or dispersible organophosphorus material. The contacting can be during washing or by pretreating by applying the composition directly to stains or by presoaking the clothing in the composition prior to washing. The present invention further relates to providing soil release benefits to all fabric in the laundry wash load in the presence of a bleaching agent. | 2008-12-18 |
20080312121 | Liquid Surface Active Compositions - A liquid surface active composition which is comprised of an alcohol ethoxysulfate, an alcohol ethoxylate, c) an additive which is triethanolamine or a diol comprised of carbon, oxygen, and hydrogen atoms and which has a molecular weight of 75 to 225, and water. | 2008-12-18 |
20080312122 | Agent for Treating Oil-Polluted Ground, and for Cleaning Oil-Contaminated Surfaces and Containers - The invention relates to a concentrate for the effective, environmentally friendly treatment of oil-polluted stretches of ground and the cleaning of oil-contaminated surfaces, said concentrate containing an emulsifier, a vegetable oil and ethanol. The emulsifier is preferably a non-ionic surfactant with an HLB value between 7 and 8. The vegetable oil is preferably selected so that it is liquid at temperatures above 5 DEG C. Oils containing unsaturated fatty acids, in particular germ oils are especially suitable. For its application as a treatment for stretches of ground, the inventive concentrate is diluted with water to form a cleaning solution and is applied to the oil-contaminated surface that is to be treated. The oil is emulsified in the inventive cleaning solution and is detached from the particles of the ground. The oil degrades in a significantly easier manner in the emulsified state. To clean oil-contaminated surfaces, the cleaning solution is sprayed onto the latter. In an advantageous embodiment of the inventive cleaning method, a powder-like adsorption agent is added to the oil emulsion that is formed during the cleaning of oil-tank interiors, said agent adsorbing the emulsified oil and forming a sediment with the latter. | 2008-12-18 |
20080312123 | HOLLOW BODY WITH A COMPARTMENT, CONTAINING A PORTION OF A WASHING, CLEANING OR RINSING AGENT - A process for producing a detergent portion, comprising the steps of forming one or more dimensionally stable hollow bodies comprising at least one compartment by injection moulding, providing one or more means for compartmentalizing the dimensionally stable hollow bodies, filling the compartment with at least one detersive formulation, and closing the compartment to form a partial or whole enclosure around the detersive formulation. | 2008-12-18 |
20080312124 | Chelate Compound-Containing Composition and Use as Detergents Thereof - The present invention provides to chelate compound-containing composition with a high concentration which is excellent in stability in high concentration alkaline condition, stable even in a long-term storage, has improved transportation efficiency, and advantageous for preservation, and a method for using a chelate compound-containing composition with a high concentration which is improved in washing capability and can exhibit a low corrosive property to glass. A high concentrated chelate compound-containing composition containing an alkaline compound and a chelate compound, wherein the chelate compound comprises a compound represented by the following formula (1); | 2008-12-18 |
20080312125 | Solvents containing cycloalkyl alkyl ethers and process for production of the ethers - The present inventions are (A) a solvent comprising at least one cycloalkyl alkyl ether (1) represented by the general formula: R1—O—R2 (wherein R1 is cyclopentyl or the like; and R2 is C1-10 alkyl or the like); (B) a method of preparations the ethers (1) characterized by reacting an alicyclic olefin with an alcohol in the presence of an acid ion-exchange resin having a water content of 5 wt % or less. The solvent is useful as cleaning solvent for electronic components, precision machinery components or the like, reaction solvent using various chemical reactions, extraction solvent for extracting objective organic substances, solvent or remover for electronic and electrical materials, and so on. The process enables industrially advantageous production of the objective cycloalkyl alkyl ethers (1). | 2008-12-18 |
20080312126 | COMPOSITIONS USEFUL AS FABRIC SOFTENER - Compositions and methods of treating textiles are disclosed. More specifically, stable compositions and methods for softening a wide range of fabrics are disclosed, including 100% cotton and hydrophobic synthetic fabrics, without detrimentally affecting the water absorbency properties of the fabrics. The compositions and methods provide desirable odor control without interfering with the stability of the product. The compositions contain at least one fatty material, water-dispersible polyolefin or at least one water-soluble or waterdispersible polyorganosiloxane, and at least one bleaching agent, preferably hydrogen peroxide. The compositions may optionally contain discrete, individual polymer particles, preferably polytetrafluoroethylene (PTFE), polyvinyl acetate (PVA), polyvinyl acetate/acrylic copolymer (PVA/a), or a combination thereof. The compositions are particularly useful when added to the rinse water in the laundering process, or in the final scouring of a fabric finishing operation. | 2008-12-18 |
20080312127 | Host Cell Comprising a Vector for Production of Proteins Requiring Gamma-Carboxylation - The present invention relates a host cell comprising an expression vector comprising a nucleic acid molecule encoding a protein requiring gamma-carboxylation and associated expression control sequences and a nucleic acid molecule encoding a vitamin K epoxido reductase and associated expression control sequences and a nucleic acid molecule encoding a γ-glutamyl carboxylase and associated control sequences. The invention further relates to a method of producing a protein requiring gamma-carboxylation in high yields. | 2008-12-18 |
20080312128 | Cellular Biomarker Antioxidant Assay and Uses Thereof - The invention encompasses cell-based systems comprising biomarkers that respond to oxidative stress (OS) in a quantitative manner, and methods of use thereof. The systems are useful for screening, identifying and testing antioxidant agents, combinations, and formulations thereof for preventing, treating, or reducing symptoms of conditions associated with oxidative damage to cells. The cell-based systems are useful for identifying effective new antioxidant agents and for optimizing antioxidant formulations for targeted therapeutic applications. One cell-based system utilizes RPE cells of the eye for identifying and optimizing antioxidant compositions effective for treatment of age-related conditions such as macular degeneration. The cell-based systems provide a convenient, inexpensive and physiologically relevant in vitro alternative to human population-based methods for testing efficacy of nutritional and pharmaceutical compositions comprising antioxidants. The invention further encompasses nutritional or pharmaceutical compositions targeting particular diseases such as AMD, formulated using methods as disclosed herein. | 2008-12-18 |
20080312129 | Use of Mas G-Protein-Coupled Receptor Agonists and Antagonists, as Apoptotic-Activity Modulators for Study, Prevention and Treatment of Diseases - The present invention is characterized by the use of Mas G-protein-coupled receptor agonists and antagonists as apoptotic activity modulators for study, prevention and treatment of diseases. It is further characterized by the use of Mas G-protein-coupled receptor agonist and antagonists for modulation of the apoptotic activity involving alterations in the activity of the protein kinase B/Akt. Another characteristic of the invention is the use of Mas G-protein-coupled receptor agonists and antagonists, including the Ang-(1-7) peptide and its analogues, agonists and antagonists, either peptidic or non-peptidic, as modulators of apoptotic activity for study, prevention and treatment of degenerative diseases of organs and systems, as an auxiliary measure for organs transplantation, treatment with embryonic, non-embryonic stem cells, re-implantation of organs and tissues and other treatments that need temporary or chronic reduction of the apoptotic activity, not limitative. The invention further claims the use of Mas G-protein-coupled receptor agonists and antagonists, including the Angiotensin-(1-7) peptide and its analogues, agonists and antagonists, either peptidic or non-peptidic, formulated with pharmaceutically and pharmacologically acceptable excipients or carriers, as modulators of the apoptotic activity. | 2008-12-18 |
20080312130 | DRUG DELIVERY VEHICLE FOR CANCER THERAPY, PROCESS FOR PRODUCING THE SAME, AND PHARMACEUTICAL PREPARATION USING THE SAME - The invention provides a vehicle that can deliver drugs specifically to the body and a pharmaceutical preparation using the same. Disclosed is a drug delivery vehicle for cancer therapy, comprising a cationized viral envelope vector, as well as a pharmaceutical preparation comprising a drug enclosed in the vehicle. The viral envelope vector is for example HVJ-E derived from a Sendai virus, and cationization can be conducted by binding hyaluronic acid-introduced cationized gelatin or ethylene glycol-introduced cationized gelatin with the viral envelope vector. The drug to be enclosed is a nucleic acid, a vector containing a nucleic acid sequence, a protein based drug or pharmaceutical with a low-molecular compound. | 2008-12-18 |
20080312131 | Regeneration of Chromatographic Stationary Phases - Process for regenerating a chromatographic stationary phase | 2008-12-18 |
20080312132 | Composition for animal consumption - This invention is directed generally to compositions (including foods, supplements, treats, toys, etc.) for animal consumption, particularly compositions that tend to aid in weight loss or reduction in weight gain, and particularly compositions that comprise one or more medium chain fatty acid triglycerides (“MCT”). This invention also is directed generally to methods for using such compositions. This invention is further directed generally to processes for making such compositions. | 2008-12-18 |
20080312133 | UNACYLATED GHRELIN AS THERAPEUTIC AGENT IN THE TREATMENT OF METABOLIC DISORDERS - An isolated polypeptide comprising any amino acid fragment of unacylated ghrelin or any analog thereof, wherein the polypeptide has an activity selected from the group consisting of a) decreasing blood glucose levels; b) increasing insulin secretion an/or sensitivity; c) binding to insulin-secreting cells; and d) promoting survival of insulin-secreting cells. As well as the use of the polypeptide in the treatment of a disorder associated with impaired glucose metabolism. | 2008-12-18 |
20080312134 | Vesicles for active macromolecule delivery - Vesicles for delivery of active macromolecules, such as oligoaminoacids, oligonucleotides, microRNA, siRNA, dsRNA, single stranded oligonucleotides, DNA, peptide nucleic acids, peptides, proteins, and some synthetic organic drugs which are made from amphiphilic segmented copolymers where one segment contains the active macromolecule. In one preferred embodiment, the active macromolecule is contained in the hydrophilic C segment of an amphiphilic ABC segmented copolymer. | 2008-12-18 |
20080312135 | MIXTURES OF DRUG-OLIGOMER CONJUGATES COMPRISING POLYETHYLENE GLYCOL, USES THEREOF, AND METHODS OF MAKING SAME - A non-polydispersed mixture of conjugates in which each conjugate in the mixture comprises a drug coupled to an oligomer that includes a polyalkylene glycol moiety is disclosed. The mixture may exhibit higher in vivo activity than a polydispersed mixture of similar conjugates. The mixture may be more effective at surviving an in vitro model of intestinal digestion than polydispersed mixtures of similar conjugates. The mixture may result in less inter-subject variability than polydispersed mixtures of similar conjugates. | 2008-12-18 |
20080312136 | Alpha 1-Antitrypsin Compositions and Treatment Methods Using Such Compositions - Alpha 1-antitrypsin compositions and treatment methods using such compositions for treating a variety of pulmonary diseases are provided. The compositions generally contain AAT, a stabilizing carbohydrate such as trehalose, a surfactant such as Polysorbate 80 and an antioxidant to stabilize AAT for use as a therapeutic. The formulations can be prepared as both liquids and solids and administered by nebulization of the liquid formulation or by conversion of dry powder formulation into an aerosol. | 2008-12-18 |
20080312137 | Fed Batch Culture Methods for Streptococci - This invention relates to the optimization of culture conditions to improve the production of bacterial capsular polysaccharides from | 2008-12-18 |
20080312138 | Erythropoietin complementation or replacement - The present invention provides methods and compositions to replace up to 90% of erythropoietin use in the treatment of anemias and hypoxias. The method employs acid and salt forms of inositol-tripyrophosphate (ITPP) isomers to shift the P | 2008-12-18 |
20080312139 | Use of Pharmaceutical Composition Containing Epidermal Growth Factor (EGF) for Diabetic foot Amputation Prevention - The invention relates to the use of Epidermal Growth Factor (EGF) in a preferably-Injectable pharmaceutical composition which is administered by means of infiltration into and around chronic cutaneous ischaemic lesions in order to prevent diabetic foot amputation. Said composition can be administered to recently-created surgical surfaces damaged by the effect of acute reperfusion with oxygenated blood following prolonged ischaemia, thereby preventing further surgical procedures and favouring the preservation of the extremity. The aforementioned composition can be used to improve (i) the cell microenvironment, thereby increasing the reparative and defensive capacity and viability of the is tissues and (ii) the cicatrisation of cutaneous ischaemic lesions, thereby stimulating cell proliferation. The invention is suitable for use in human, veterinary and experimental medicine, specifically in vascular angiology and surgery, dermatology, burn treatment and reconstructive surgery and geriatric medicine. Said composition can be used for recalcitrant ulcers which are associated with lesions in the macro and/or microvasculature, patients with inadequate lymphatic and/or venous return and ulcers or other lesions which are difficult to cicatrise and/or heal. | 2008-12-18 |
20080312140 | Compositions and Methods for Preventing or Treating Hiv Infection - The present invention is directed to compositions and methods of preventing for treating a retroviral infection, more particularly an HIV (human immunodeficiency virus) infection, and even more particularly an HIV-1 infection. The compositions and methods involve molecules that mimic the active site of the human CD4 protein. | 2008-12-18 |
20080312141 | PEPTIDE LIGANDS FOR PROSTATE SPECIFIC ANTIGEN - The present invention relates to novel peptide ligands for prostate specific antigen (PSA) binding specifically with it and enhancing its enzyme activity, to a process for preparation of these peptides, to diagnostic and pharmaceutical compositions comprising these peptides, to the use of these peptides for pharmaceutical and research preparations, to methods using these peptides in diagnostic assays for determination of the concentrations of various molecular forms of PSA, to methods for modulating the PSA enzyme activity and PSA activity dependent conditions by using these peptides either in vivo or in vitro and to the use of these peptides in procedures for biochemical isolation and purification of PSA. | 2008-12-18 |
20080312142 | Composition for Increasing Body Height - This invention provides a composition for increasing a body height of a patient with short stature or an individual other than patients with short stature. More specifically, the invention provides: a composition for increasing the body height of an individual comprising a guanyl cyclase B (GC-B) activator as an active ingredient, the composition being to be administered to an individual free from FGFR3 abnormality; a method for increasing the body height of an individual free from FGFR3 abnormality which comprises activating GC-B; a method for screening an agent for increasing the body height of an individual which comprises selecting an agent for increasing the body height using GC-B activity as an indication; and a method for extending a cartilage bone free from FGFR3 abnormality which comprises activating GC-B in an individual. | 2008-12-18 |
20080312143 | Modified Cdna for High Expression Levels of Factor VIII and Its Derivatives - The present invention relates to modified DNA sequences coding for biologically active recombinant human factor VIII and its derivatives, recombinant expression vectors containing such DNA sequences, host cells transformed with such recombinant expression vectors, and processes for the manufacture of the recombinant human factor VIII and its derivatives. The invention also covers a transfer vector for use in human gene therapy which comprises such modified DNA sequences. The present invention relates to modified DNA sequences coding for biologically active recombinant human factor VIII and its derivatives, recombinant expression vectors containing such DNA sequences, host cells transformed with such recombinant expression vectors, and processes for the manufacture of the recombinant human factor VIII and its derivatives. The invention also covers a transfer vector for use in human gene therapy which comprises such modified DNA sequences. | 2008-12-18 |
20080312144 | Peptides for the Treatment of Herpes Virus Infections - The present invention relates to the use of a peptide having the amino acid sequence | 2008-12-18 |
20080312145 | Agent for Regulating Bone Formation - The present invention provides preventive, ameliorating, and/or therapeutic agents for diseases caused by a disturbed balance between bone formation and bone resorption. The decoys of the present invention induce normal bone metabolism by inhibiting the differentiation-inducing factors of cells involved in bone metabolism. For example, bone resorption can be controlled by using a decoy of the present invention to inhibit NF-κB, a transcriptional regulatory factor that regulates osteoclast differentiation. This method uses a mechanism different from those of previous pharmaceutical agents; therefore, one can expect it to be effective for cases in which existing pharmaceutical agents were not effective. | 2008-12-18 |
20080312146 | METH1 and METH2 Polynucleotides and Polypeptides - The present invention relates to novel anti-angiogenic proteins, related to thrombospondin. More specifically, isolated nucleic acid molecules are provided encoding human METH1 and METH2. METH1 and METH2 polypeptides are also provided, as are vectors, host cells and recombinant methods for producing the same. Also provided are diagnostic methods for the prognosis of cancer and therapeutic methods for treating individuals in need of an increased amount of METH1 or METH2. Also provided are methods for inhibiting angiogenesis using METH1 or METH2. | 2008-12-18 |
20080312147 | Compositions and Methods for the Regulation of Hair Growth - A novel hair loss prevention and hair restoration composition, is applied topically to the scalp. The composition and methods of application stimulate the hair follicle, encourage angiogenesis, and improve blood circulation throughout the area where the composition is applied. Moreover, formation of di-hydroxytestosterone is inhibited using copper peptides that interfere with 5-α-reductase activity that would otherwise convert testosterone to di-hydroxytestosterone. | 2008-12-18 |
20080312148 | RECOMBINANT HUMAN INTERFERON-LIKE PROTEINS - This application relates to recombinant human interferon-like proteins. In one embodiment a recombinant protein created by gene shuffling technology is described having enhanced anti-viral and anti-proliferative activities in comparison to naturally occurring human interferon alpha 2b (HuIFN-α2b). The invention encompasses a polynucleotide encoding the protein and recombinant vectors and host cells comprising the polynucleotide. Preferably the polynucleotide is selected from the group of polynucleotides each having a sequence at least 93% identical to SEQ ID: No. 1 and the protein is selected from the group of proteins each having an amino acid sequence at least 85% identical to SEQ ID No: 2. The proteins and compositions comprising the proteins can be used for treatment of conditions responsive to interferon therapy, such as viral diseases and cancer. | 2008-12-18 |
20080312149 | Health Food and Pharmaceutical Composition for Amelioration of Disease Induced by Metabolic Disorder in Cartilage - The invention relates to a health food and a pharmaceutical preparation, containing a composition for treating rheumatoid arthritis. The health food and pharmaceutical preparation in which glucosamine, a collagen and an isoflavone aglycone act synergically, which are useful for relieving symptoms or treatment of diseases related to abnormal cartilage metabolism, especially rheumatoid arthritis. | 2008-12-18 |
20080312150 | Treatment and analysis of proliferative disorders - A method of treating a subject having unwanted cell proliferation which includes: inducing differentiation in a cell; providing said cell with a photosensitizer; and activating said PS, thereby the treating unwanted cell proliferation. | 2008-12-18 |
20080312151 | COMPOSITIONS AND METHODS INCLUDING EXPRESSION AND BIOACTIVITY OF BOVINE FOLLICLE STIMULATING HORMONE - The present invention provides methods of producing biologically active recombinant bFSH and methods of increasing reproduction in mammals, particularly bovine, using recombinant bFSH. Also provided are methods of producing single chain recombinant bFSH. The recombinant bFSH of the present invention increases superovulation, embryo development, and reproductive efficiency in cattle and other ungulates. | 2008-12-18 |
20080312152 | Glycosylated Probnp - The present invention is directed to glycosylated proBNP and pharmaceutical compositions thereof. The present invention also relates to novel assays for measuring the total natriuretic activity that is present in a clinical blood sample. | 2008-12-18 |
20080312153 | PYRAZOLE DERIVATIVE, MEDICINAL COMPOSITION CONTAINING THE SAME, MEDICINAL USE THEREOF, AND INTERMEDIATE FOR PRODUCTION THEREOF - The present invention provides pyrazole derivatives represented by the general formula: | 2008-12-18 |
20080312154 | ADMINISTRATION OF ADIPOCYTOKINE AND ADIPONECTIN FOR TREATING HEADACHE AND METHODS OF DIAGNOSING HEADACHE BY MEASURING ADIPONECTIN - Methods for treating a headache, such as a migraine, in a subject comprising administering a therapeutically effective amount of an adipocytokine, for example, adiponectin, to the subject are disclosed. Pharmaceutical compositions comprising adipocytokine, for example, adiponectin, are disclosed. Methods of diagnosing the presence or absence of a headache in a subject, such as a migraine, by assessing the level of adiponectin in the subject are disclosed. | 2008-12-18 |
20080312155 | Metastin Derivatives and Use Thereof - The invention provides stable metastin derivatives having excellent biological activities (a cancer metastasis suppressing activity, a cancer growth suppressing activity, etc.). By modifying the constituent amino acids of metastin with specific modifying groups, metastin derivatives having more improved blood stability, etc. than native metastin and showing excellent cancer metastasis suppressing activity or cancer growth suppressing activity have been found. Furthermore, it has been found that these metastin derivatives exhibit effects of suppressing gonadotropic hormone secretion, suppressing sex hormone secretion, etc., which are wholly different from the effects heretofore known. | 2008-12-18 |
20080312156 | In-Situ Crosslinkable Elastin-Like Polypeptides for Defect Filling in Cartilaginous Tissue Repair - Defects in a cartilaginous tissue are filled by: (a) mixing (i) a first reagent composition preferably comprising an amine-free hydroxyalkyl (preferably hydroxymethyl) phosphine crosslinking agent with (ii) a second reagent composition comprising a bioelastic polymer, the bioelastic polymer preferably comprising elastomeric units, the elastomeric units preferably selected from the group consisting of bioelastic pentapeptides, tetrapeptides, and nonapeptides; to produce a therapeutic composition; and then (b) administering the therapeutic composition to the cargilagenous tissue. Compositions and kits for carrying out the method are also described. | 2008-12-18 |
20080312157 | GIP ANALOG AND HYBRID POLYPEPTIDES WITH SELECTABLE PROPERTIES - The present invention relates generally to novel GIP analogs and GIP hybrid polypeptides with selectable properties, useful as agents for the treatment and prevention of metabolic diseases and disorders, for example those which can be alleviated by control plasma glucose levels, insulin levels, and/or insulin secretion, positive inotropic effects, reduction of catabolic effects, slowing of gastric emptying. Such conditions and disorders include, but are not limited to, hypertension, dyslipidemia, cardiovascular disease, eating disorders, critical care, insulin-resistance, obesity, and diabetes mellitus of any kind, including type 1, type 2, and gestational diabetes. | 2008-12-18 |
20080312158 | Semaphorin Gene Family - A novel class of proteins, semaphorins, nucleic acids encoding semaphorins, semaphorin peptides, and methods of using semaphorins and semaphorin-encoding nucleic acids are disclosed. Semaphorin peptides and receptor agonists and antagonists provide potent modulators of nerve cell growth and regeneration. The invention provides pharmaceutical compositions, methods for screening chemical libraries for regulators of cell growth/differentiation; semaphorin gene-derived nucleic acids for use in genetic mapping, as probes for related genes, and as diagnostic reagents for genetic neurological disease; specific cellular and animal systems for the development of neurological disease therapy. | 2008-12-18 |