50th week of 2011 patent applcation highlights part 30 |
Patent application number | Title | Published |
20110305587 | MOTOR DRIVE PARTICULARLY FOR SUBMERSED ELECTRIC PUMPS - A motor drive, particularly for submersed electric pumps, has a jacket closed hermetically by a bottom and a head in order to form a first hermetic chamber, which contains an electric motor that is immersed in a bath of dielectric cooling liquid; the jacket is associated with an enclosure in order to form a second hermetic chamber, which contains a power supply and control unit connected to the electric motor. The motor drive includes a compensation means that balances the variations in volume of the dielectric cooling liquid and generates an overpressure within the first hermetic chamber, the first hermetic chamber is substantially independent of the second hermetic chamber. | 2011-12-15 |
20110305588 | FLUID TRANSPORTER - A fluid transporter includes: a rotor; a fluid delivery channel which has a groove having a circular-arc shape around a rotation axis of the rotor and disposed on a surface of a channel frame opposed to the rotor, and a sheet-shaped elastic member sealing an opening of the groove; and a plurality of pressing members disposed between the rotor and the elastic member to sequentially and repeatedly open and close the delivery channel from the upstream side to the downstream side by deforming the elastic member in accordance with the rotation of the rotor. | 2011-12-15 |
20110305589 | ECCENTRIC SCREW PUMP - The invention relates to an eccentric screw pump ( | 2011-12-15 |
20110305590 | METHOD OF FABRICATING AN OBJECT - A method of fabricating an object is disclosed. A first layer of powder is deposited onto a substrate in a configuration defining a first cross-section of the object, and is consolidated by laser irradiation. To fabricate the object, further layers of powder are deposited onto the sintered first layer of powder to define further cross-sections of the object. The further layers are consolidated. A heat source is applied to the substrate to mitigate distortion of the substrate during fabrication of the object. | 2011-12-15 |
20110305591 | LOW DENSITY AND HIGH DUCTILITY ALLOY FOR A GOLF CLUB HEAD - A low density high ductility alloy for making a golf club head is composed of 31 to 36 w. t. % of Manganese (Mn), 6 to 10 w. t. % of Aluminum (Al), 0.3 to 1 w. t. % of Carbon (C), 4 to 8 w. t. % of Chromium (Cr), 0.2 to 0.6 w. t. % of Silicon (Si), and other component is iron (Fe). The density of the alloy is 6.8˜7 g/cm | 2011-12-15 |
20110305592 | STEEL MATERIAL COMPOSITION FOR PRODUCING PISTON RINGS AND CYLINDER LINERS - A steel material composition, in particular for producing piston rings and cylinder liners, comprises the following elements in the listed quantities, relative to 100% by weight of the steel material: 0.5-1.2% by weight C, 0-3.0% by weight Cr, 72.0-94-5% by weight Fe, 3.0-15.0% by weight Mn and 2.0-10.0% by weight Si. The composition can be produced by producing a melt of the starting materials and casting the melt in a prefabricated mold. | 2011-12-15 |
20110305593 | STEEL AND COUPLER MADE FROM THE SAME - The present invention provides a type of steel and a coupler made from same, comprising the following compositions in percentages by weight: carbon: 0.24-0.32%, silicon: 0.20-0.50%, manganese: 1.30-1.70%, phosphorus: less than or equal to 0.02%, sulphur: less than or equal to 0.02%, copper: less than or equal to 0.30%, chromium: 0.50-0.80%, nickel: 0.40-0.70%, molybdenum: 0.25-0.45%, aluminium: 0.02-0.08%, and the remainders are iron and other inevitable elements. The steel of the present invention is advantaged in high strength and excellent toughness and therefore the mechanical property thereof is better than the standard of conventional grade E steel. | 2011-12-15 |
20110305594 | STEEL MATERIAL COMPOSITION FOR PRODUCING PISTON RINGS AND CYLINDER SLEEVES - The invention relates to a steel material composition, in particular for producing piston rings and cylinder sleeves, containing the following elements in the given fractions in relation to 100% by weight of the steel material: 0.03-2.0% by weight B, 0.5-1.2% by weight C, 70.1-97.3% by weight Fe, 0.1-3.0% by weight Mn and 2.0-10.0% by weight Si. Said composition can be produced by melting the starting materials and casting the melt in a pre-fabricated mould. | 2011-12-15 |
20110305595 | HYDROGEN FATIGUE RESISTANT FERRITIC STEEL AND MANUFACTURING METHOD THEREOF - A ferritic steel having tensile properties and fatigue properties capable of withstanding use in a hydrogen environment and a method of manufacture thereof are provided. By adding one or more element selected from among vanadium (V), titanium (Ti) and niobium (Nb) so that the steel includes, together with at least ferrite grains in the structure, a carbide or carbides of one or more element selected from among V, Ti and Nb, the reduction of area and the fatigue crack propagation rate of the ferritic steel in a hydrogen environment are improved. The advantages of the invention were confirmed in cases where the ferrite grains are small grains of 1 μm or less in size, and in cases where the ferrite grains are coarse grains from several micrometers to 20 μm in size, and moreover in cases where the ferrite grains are coarse grains from several micrometers to 60 μm in size. | 2011-12-15 |
20110305596 | METHOD FOR REDUCING ALLERGENICITY IN INDOOR SPACES - According to this invention, allergenicity in an indoor space is reduced by denaturing allergens in allergen reservoirs that are capable of producing respiratory or skin reactions and physically removing the allergens from the allergen reservoirs in the indoor space. The allergen reservoirs may also be treated with pesticides and fungicides/fungistats to prevent reinfestation of house dust mites, molds and cockroaches. | 2011-12-15 |
20110305597 | UV STERILIZATION OF CONTAINERS - Provided herein are systems, devices, and methods for ultraviolet (UV) disinfection and sterilization, more specifically, systems, devices, and methods for UV disinfection and sterilization of a container, and more particularly systems, devices, and methods for UV disinfection and sterilization of a container used in the process of fermentation for an alcoholic beverage. Provided are also systems, UV devices, and methods for inhibiting the growth of one or more species of microorganisms present in a container, preferably for inhibiting the growth of one or more species of microorganisms present on an interior surface of a container. | 2011-12-15 |
20110305598 | MICROFLUIDIC DEVICE - A microfluidic device is described herein which comprises a micron-sized deep flow channel and a sensor. The micron-sized deep flow channel is configured such that a sample solution and a reference solution flow side-by-side to one another in a single sensing region of the sensor. The single sensing region is divided into a detection region and a reference region which are contiguous to one another and which are respectively interfaced with the sample solution and the reference solution that flow side-by-side to one another in a longitudinal direction within the micron-sized deep flow channel. | 2011-12-15 |
20110305599 | OPTICAL SENSOR OF BIO-MOLECULES USING THIN-FILM INTERFEROMETER - The present invention is directed to an assembly for use in detecting an analyte in a sample based on thin-film spectral interference. The assembly comprises a waveguide, a monolithic substrate optically coupled to the waveguide, and a thin-film layer directly bonded to the sensing side of the monolithic substrate. The refractive index of the monolithic substrate is higher than the refractive index of the transparent material of the thin-film layer. A spectral interference between the light reflected into the waveguide from a first reflecting surface and a second reflecting surface varies as analyte molecules in a sample bind to the analyte binding molecules coated on the thin-film layer. | 2011-12-15 |
20110305600 | MICROCHIP SOLUTION SENDING SYSTEM - [Technical Problem] | 2011-12-15 |
20110305601 | Electrical Heating Catalyzer Having Honeycomb Structure - A honeycomb body of a honeycomb structure is made of ceramic, and a plurality of electrodes are provided apart from one another on a surface of the honeycomb body. In the honeycomb body, energization is performed for each of a plurality of current paths Xa to Xc formed by the plurality of electrodes, thereby heating the honeycomb body. A controlling device detects heater current Ia, Ib, and IC that flow when a predetermined voltage is applied for each of the plurality of current paths Xa, Xb, and Xc, and controls an energization timing of each current path Xa to Xc based on the detection results. | 2011-12-15 |
20110305602 | APPARATUS FOR THE REDUCTION OF GASOLINE BENZENE CONTENT BY ALKYLATION WITH DILUTE ETHYLENE - The apparatus converts ethylene in a dilute ethylene stream and dilute benzene in an aromatic containing stream via alkylation to heavier hydrocarbons. The catalyst may be a zeolite such as UZM-8. The catalyst is resistant to feed impurities such as hydrogen sulfide, carbon oxides, and hydrogen and selectively converts benzene. At least 40 wt-% of the ethylene in the dilute ethylene stream and at least 20 wt-% of the benzene in the dilute benzene stream can be converted to heavier hydrocarbons. | 2011-12-15 |
20110305603 | Embedded Photocatalyst for Hydrogen Perioxide Protection - Embodiments of the present invention combine a suitable photocatalyst with a non-conducting matrix such as plastic or rubber for the purpose of the production of hydrogen peroxide in the presence of light of a suitable frequency or frequencies and oxygenated, acidic water. A suitable photocatalyst such as Anatase titanium dioxide is combined at low temperature (>˜700 F) with a plastic such as polypropylene as one would a pigment. The impregnated plastic can be immersed in water to about an inch whereupon the excess hydrogen ion in the water combines with dissolved oxygen to produce hydrogen peroxide upon irradiation. Hydrogen peroxide is a excellent oxidizer and disinfectant and purifier and goes on to kill bacteria, algae, etc. in the water, as well as to precipitate hardness. Unused hydrogen peroxide breaks down into hydrogen ion and free oxygen in a short time. | 2011-12-15 |
20110305604 | REACTOR FOR PRODUCING POLYCRYSTALLINE SILICON USING THE MONOSILANE PROCESS - A reactor that produces polycrystalline silicon using a monosilane process includes a reactor base plate having a multiplicity of nozzles formed therein through which a silicon-containing gas flows, a plurality of filament rods mounted on the reactor base plate, and a gas outlet opening located at a selected distance from the nozzles to feed used monosilane to an enrichment and/or treatment stage, wherein the gas outlet opening is formed at a free end of an inner tube, the inner tube is conducted through the reactor base plate, and the inner tube has an outer wall and an inner wall and thus forms an intermediate space in which at least one cooling water circuit is conducted. | 2011-12-15 |
20110305605 | PROTECTIVE COATING FOR METALLIC SURFACES AND PRODUCTION THEREOF - This specification describes the use of a composition comprising a nanoscale powder, a porous ceramic powder and a solvent for protecting a metallic surface against chemical attacks at high temperatures, in particular in a reducing and/or carburizing atmosphere, and also a corresponding process. Furthermore, this specification describes a plant part having a metallic surface which, in the operating state, is exposed to a reducing and/or carburizing atmosphere, wherein the surface is coated with a porous protective coating having a specific surface area of at least 20 m | 2011-12-15 |
20110305606 | Apparatus and Method for Vaporizing Natural Substances - A vaporizer unit having two air streams that converge to one. The vaporizer measures temperature differentials between a heating chamber and a chamber outlet and based on such measurements indicates to a user whether or not compound is present in an air stream, Additionally, the vaporizer is connectible to a smartphone. A connected smarthphone controls the functions of the vaporizer and receives information about conditions of the same. | 2011-12-15 |
20110305607 | MICROFLUIDIC DEVICE HAVING MICROVALVE - A microfluidic device including a microvalve includes a first substrate, a second substrate facing the first substrate, an elastic film between the first and second substrates, a microfluidic channel on the second substrate, a valve seat of the second substrate protruding in the microfluidic channel, and a fine structure on a surface of the elastic film, facing the valve seat and which contacts the valve seat when the microvalve is operated. | 2011-12-15 |
20110305608 | TRANSFER UNIT FOR ANALYSIS DEVICES - The invention relates to a transfer unit for analysis devices, containing a tube-shaped assembly which can be heated by an electric heater in a programmed manner, a tube ( | 2011-12-15 |
20110305609 | GASIFICATION SYSTEMS FOR PARTIAL MODERATOR BYPASS - Methods and systems for a gasifier having a partial moderator bypass are provided. The gasifier includes a partial oxidation reactor including an inlet and an outlet and a primary reaction zone extending therebetween, the partial oxidation reactor configured to direct a flow of products of partial oxidation including fuel gases, gaseous byproducts of partial oxidation, and unburned carbon, and a secondary reaction chamber coupled in flow communication with the partial oxidation reactor, the secondary reaction chamber is configured to mix a flow of moderator with the flow of gaseous byproducts of partial oxidation and unburned carbon such that a concentration of fuel gases is increased. | 2011-12-15 |
20110305610 | METHOD FOR IMPREGNATING A POROUS BODY BY A SUSPENSION AND INSTALLATION FOR IMPLEMENTING SAME - The present invention relates to a method for impregnating a porous body ( | 2011-12-15 |
20110305611 | APPARATUS AND METHODS FOR TREATING EXHAUST GASES - The present invention, in some embodiments, provides catalyst modules and/or catalytic reactors having increased effective catalyst cross-sectional areas. In some embodiments, a catalyst module comprises a fluid stream inlet side comprising a plurality of first catalyst bodies and a plurality of first ducts and a fluid stream outlet side comprising a plurality of second catalyst bodies and a plurality of second ducts, wherein the first ducts are a fluid stream inlet to the second catalyst bodies and the second ducts are a fluid stream outlet for the first catalyst bodies. | 2011-12-15 |
20110305612 | NOX STORAGE CATALYST WITH IMPROVED HYDROCARBON CONVERSION ACTIVITY - Described is a nitrogen oxide storage catalyst comprising:
| 2011-12-15 |
20110305613 | Fe-BEA/Fe-MFI Mixed Zeolite Catalyst And Process For The Treatment Of NOx In Gas Streams - Disclosed is a catalyst, preferably for use in selective catalytic reduction (SCR), said catalyst comprising one or more zeolites of the MFI structure type, and one or more zeolites of the BEA structure type, wherein at least part of the one or more zeolites of the MFI structure type and at least part of the one or more zeolites of the BEA structure type respectively contain iron (Fe). Furthermore, an exhaust gas treatment system is described, comprising said catalyst as well as a process for the treatment of a gas stream comprising NO | 2011-12-15 |
20110305614 | Cu-CHA/Fe-MFI Mixed Zeolite Catalyst And Process For The Treatment Of NOx In Gas Streams - Described is a catalyst, preferably for use in selective catalytic reduction (SCR), said catalyst comprising one or more zeolites of the MFI structure type, and one or more zeolites of the CHA structure type, wherein at least part of the one or more zeolites of the MFI structure type contain iron (Fe), and wherein at least part of the one or more zeolites of the CHA structure type contain copper (Cu). An exhaust gas treatment system is described, comprising said catalyst as well as a process for the treatment of a gas stream comprising NO | 2011-12-15 |
20110305615 | NOx Storage Catalyst With Reduced Rh Loading - The present invention relates to a nitrogen oxide storage catalyst comprising:
| 2011-12-15 |
20110305616 | CONFIGURATION OF CONTACTING ZONES IN VAPOR LIQUID CONTACTING APPARATUSES - Vapor-liquid contacting apparatuses comprising a primary contacting zone and a secondary contacting zone are disclosed. A representative secondary contacting zone is a secondary absorption zone, such as a finishing zone for subsequent contacting of the vapor effluent from the primary contacting zone to further remove impurities and achieve a desired purity of purified gas exiting the secondary absorption zone. The secondary contacting zone is disposed below the primary contacting zone, such that the secondary contacting zone, which must operate efficiently in removing generally trace amounts of remaining impurities, is more protected from movement than the more elevated, primary or initial contacting stages for bulk impurity removal. The apparatuses are therefore especially beneficial in offshore applications where they are subjected to rocking. | 2011-12-15 |
20110305617 | CATALYST AND METHOD FOR REMOVING FORMALDEHYDE USING THE SAME - The present invention relates to a catalyst including a ceramic structure containing porous ceramic paper and a catalyst component supported on the ceramic structure, and to a method for removing formaldehyde using the catalyst. The present invention provides a catalyst in which a structure made of ceramic paper having excellent characteristics in terms of porosity, specific surface area, and the like is used as a support for the catalyst component to maximize an effective area for reacting the supported catalyst component with a substance to be treated, thereby improving catalyst performance. The present invention also provides a method of using the catalyst. | 2011-12-15 |
20110305618 | METHOD FOR SYNTHESIS OF A RADIONUCLIDE-LABELED COMPOUND USING AN EXCHANGE RESIN - The invention pertains to a method for eluting a radionuclide-label or a radionuclide-labeled compound using a solid phase extraction resin, to a device for performing such a method, and to a computer program for controlling such a device. | 2011-12-15 |
20110305619 | Silicon Containing Halogenide, Method for Producing the Same, and Use of the Same - The invention relates to silicon containing halogenide obtained by thermal disintegration of halogenized polysilane, and a method for producing the silicon. The silicon has a halogenide content of 1 at %-50 at %. The invention further relates to the use of the silicon containing halogenide for purifying metallurgical silicon. | 2011-12-15 |
20110305620 | Method for producing halogenated oligomers and/or halogenated polymers of elements of the third to fifth main group - The invention relates to a method for producing halogenated oligomers and/or halogenated polymers of elements of the third to fifth main group, wherein the halogenated oligomers and/or halogenated polymers are synthesized from a first chain-forming agent and a second chain-forming agent in a plasma-chemical reaction. At least one of the two chain-forming agents is a halogen compound of an element of the third to fifth main group. | 2011-12-15 |
20110305621 | Method Of Continuously Producing Tetrafluorosilane By Using Various Fluorinated Materials, Amorphous Silica And Sulfuric Acid - The present invention relates to a method of continuously producing tetrafluorosilane (SiF | 2011-12-15 |
20110305622 | DEVICE AND METHOD FOR THE PRODUCTION OF SILICON BLOCKS - A device for the production of silicon blocks comprises a vessel for receiving a silicon melt, the vessel comprising a vessel wall comprising at least one side wall and a bottom as well as an inside and an outside and a central longitudinal axis, and means for creating a temperature field on the inside of the bottom, the temperature field having a temperature gradient at the bottom of the vessel which is perpendicular to the central longitudinal axis at least in some regions when the silicon melt cools down for crystallization. | 2011-12-15 |
20110305623 | Hydrocarbon and alcohol fuels from variable, renewable energy at very high efficiency - A Renewable Fischer Tropsch Synthesis (RFTS) process is disclosed for producing hydrocarbons and alcohol fuels from wind energy, waste CO | 2011-12-15 |
20110305624 | METHOD FOR PRODUCTION OF LITHIUM CARBONATE - The present invention relates to a process for producing lithium carbonate from brine by precipitating calcium ions by reacting brine with schoenite to yield carnallite, Gypsum, and lithium, wherein the brine comprises of salts of one or more of sodium, magnesium, and potassium chloride and then reacting that lithium chloride solution with sodium carbonate to give lithium carbonate. | 2011-12-15 |
20110305625 | METHOD FOR MAKING SEMICONDUCTING CARBON NANOTUBES - A method for making semiconducting carbon nanotubes is provided. A catalyst precursor is disposed on a substrate. The catalyst precursor includes blood. Organic substances contained in the blood are removed and iron ions contained in the blood are oxidized to yield discrete ferric oxide nano-particles on the substrate. The ferric oxide nano-particles are reduced to yield isolated iron nano-particles on the substrate. Carbon nanotubes then grow on the iron nano-particles. | 2011-12-15 |
20110305626 | Method of Synthesizing Pyrite Nanocrystals - A method of synthesizing pyrite nanocrystals is disclosed which in one embodiment includes forming a solution of iron (III) diethyl dithiophosphate and tetra-alkyl-ammonium halide in water. The solution is heated under pressure. Pyrite nanocrystal particles are then recovered from the solution. | 2011-12-15 |
20110305627 | PROCESSES FOR HYDROGEN PRODUCTION AND CATALYSTS FOR USE THEREIN - This invention describes a process for producing hydrogen comprising: introducing a feedstream comprising a bio-based feedstock and water into a reformer and supplying heat to the reformer; contacting the feedstream with a steam reforming catalyst disposed within the reformer to form a reformate comprising hydrogen and carbon monoxide; recovering the reformate from the reformer; contacting the reformate with steam in the presence of a water-gas shift catalyst disposed within a water-gas shift reaction zone to form a water-gas shift product stream comprising hydrogen, and the water-gas shift product stream comprises hydrogen in a greater quantity than in the reformate; heating the feedstream by heat exchange contact of the feedstream with a product stream selected from the reformate, the water-gas shift product stream or combinations thereof to transfer heat from the product stream to the feedstream prior to introducing the feedstream into the reformer. | 2011-12-15 |
20110305628 | PROCESS FOR PRODUCING HYDROGEN AT LOW TEMPERATURE - An oxidative steam reforming of methanol (OSRM) process at low temperature includes providing a gas mixture comprising methanol, steam and oxygen and conducting the gas mixture to flow through an AuCu/ZnO-based catalyst for undergoing OSRM process to generate hydrogen, wherein an initiation temperature of OSRM is less than 175° C. The AuCu/ZnO catalyst of the present invention may lower the initiation temperature of the OSRM process and remains to have good catalytic efficiency without undergoing pre-reduction. A steam reforming of methanol (SRM) process is also herein provided. | 2011-12-15 |
20110305629 | Anti-Alpha v Beta 6 Antibodies and Uses Thereof - The present invention is in the fields of cell biology, immunology and oncology. The invention provides humanized antibodies that recognize α | 2011-12-15 |
20110305630 | MISFOLDED PROTEINS IN CANCER TREATMENT AND DIAGNOSIS - Cancer cells are identified and inhibited using agents that bind to epitopes unique to misfolded forms of surface proteins presented by the cancer cells. In one embodiment, cancer cells are identified and treated using antibodies that bind to a YYX epitope available on the misfolded form of the prion protein, PrP, which has been identified on various cancer cell lineages. | 2011-12-15 |
20110305631 | Camptothecin Conjugates of Anti-CD22 Antibodies for Treatment of B Cell Diseases - Disclosed herein are compositions and methods of use comprising combinations of anti-CD22 antibodies with a therapeutic agent. The therapeutic agent may be attached to the anti-CD22 antibody or may be separately administered, either before, simultaneously with or after the anti-CD22 antibody. In preferred embodiments, the therapeutic agent is an antibody or fragment thereof that binds to an antigen different from CD22, such as CD19, CD20, CD21, CD22, CD23, CD37, CD40, CD40L, CD52, CD80 and HLA-DR. However, the therapeutic agent may an immunomodulator, a cytokine, a toxin or other therapeutic agent known in the art. More preferably, the anti-CD22 antibody is part of a DNL complex, such as a hexavalent DNL complex. Most preferably, combination therapy with the anti-CD22 antibody or fragment and the therapeutic agent is more effective than the antibody alone, the therapeutic agent alone, or the combination of anti-CD22 antibody and therapeutic agent that are not conjugated to each other. Administration of the anti-CD22 antibody and therapeutic agent induces apoptosis and cell death of target cells in diseases such as B-cell lymphomas or leukemias, autoimmune disease or immune dysfunction disease. | 2011-12-15 |
20110305632 | PROCESS FOR THE PREPARATION OF ASYMMETRICAL BIS(THIOSEMICARBAZONES) - The present invention relates to a method of making asymmetrical bis(thiosemicarbazones), compounds useful as synthetic intermediates in the method, new bis(thiosemicarbazones) that can be readily accessed by use of the method and methods of treatment and imaging utilising some of the new bis(thiosemicarbazones). | 2011-12-15 |
20110305633 | Methods for Treatment, the Prognostic Assessment and the Detection of Breast Cancer - The present invention relates to methods for the treatment, the prognostic assessment and the detection of breast cancer. | 2011-12-15 |
20110305634 | Methods and systems for adenovirus interaction with desmoglein 2 (DSG2) - The present invention provides compositions and methods for treating disorders associated with epithelial tissues. | 2011-12-15 |
20110305635 | MYELIN DETECTION USING BENZOFURAN DERIVATIVES - The present invention relates to methods for the detection of myelin and a quantitative measurement of its local concentration in a sample using a benzofuran compound or its radioisotope derivatives. In one embodiment a method of myelin detection comprises identifying a subject at risk of or diagnosed with a myelin-associated neuropathy, parenterally administering to the subject the benzofuran compound, or a derivative of the compound, and determining myelination in the subject by detecting binding in the sample. In one embodiment, the invention provides a method of imaging myelinated tissue in a surgical field of mammalian tissue comprising the steps of contacting the surgical site with the benzofuran compound or a radioisotope derivative of the compound, and detecting binding in the surgical site. In yet another embodiment, a method of imaging spinal cord and spinal nerve root tissue is provided comprising the steps of parenteral administration of a radioisotope derivative of the benzofuran compound and detecting the radioisotope derivative within the spinal canal and intervertebral foramen. Methods of quantification of binding of the benzofuran compound or its derivatives are also provided. | 2011-12-15 |
20110305636 | COMPOUNDS, COMPOSITIONS, METHODS OF SYNTHESIS, AND METHODS OF TREATMENT - Briefly described, embodiments of this disclosure include compounds as described herein, labeled compounds as described herein, pharmaceutical composition including compounds described herein, methods of imaging, method of forming a compound as described herein, and the like. In particular, embodiments of the disclosure include a series of triamino-pyridine derivatives and labeled triamino-pyridine derivatives, methods of synthesizing these compounds, intermediate compounds, methods of treatment using these compounds, methods of imaging, diagnosing, localizing, monitoring, and/or assessing a condition (e.g., corticotropin releasing factor type-1 (CRF1)) and/or related biological events, using triamino-pyridine derivatives, and the like. In addition, the present disclosure includes compositions (e.g., labeled triamino-pyridine derivatives that are ligands for the CRF1 receptor) used in and methods relating to non-invasive imaging (e.g., positron emission tomography (PET) imaging or SPECT imaging). | 2011-12-15 |
20110305637 | RADIOLABELLED PDE10 LIGANDS - The present invention relates to novel, selective, radiolabeled PDE10 ligands which are useful for imaging and quantifying the PDE10A enzyme in tissues using positron-emission tomography (PET). The invention is also directed to compositions comprising such compounds, to processes for preparing such compounds and compositions, and to the use of such compounds and compositions for imaging a tissue, cells or a host, in vitro or in vivo. | 2011-12-15 |
20110305638 | Modulation of Macrophage Activation - The invention provides methods for treating pathological conditions associated with an undesirable inflammatory component. The invention is generally directed to reducing inflammation by administering cells that modulate macrophage activation. The invention is also directed to drug discovery methods to screen for agents that modulate the ability of the cells to modulate macrophage activation. The invention is also directed to cell banks that can be used to provide cells for administration to a subject, the banks comprising cells having desired potency to modulate macrophage activation. | 2011-12-15 |
20110305639 | METHOD AND FORMULATION FOR REDUCING AGGREGATION OF A MACROMOLECULE UNDER PHYSIOLOGICAL CONDITIONS - The invention provides a method for reducing aggregation and inhibiting flocculation of a macromolecule, such as a protein, under physiological conditions, by the addition of certain cyclodextrins (CDs). The invention also provides a method to minimize inflammation at the injection site during subcutaneous administration of a macromolecule and pharmaceutical formulations for such administration. Further the invention provides methods of treating a CD20 positive cancer or an autoimmune disease, comprising administering a humanized anti-CD20 antibody in a pharmaceutical formulation of the invention. The invention further provides an in vitro dialysis method to evaluate the ability of an excipient to reduce aggregation of an antibody or other macromolecule under physiological conditions. | 2011-12-15 |
20110305640 | METHOD TO TREAT PSORIASIS AND OTHER HYPERPROLIFERATIVE SKIN DISORDERS - Soluble adenylyl cyclase (sAC) is implicated in proliferation of keratinocytes. Inhibitors of sAC are useful for the treatment and/or prevention of psoriasis and other hyperproliferative skin disorders. Assays to identify such compounds are also described. | 2011-12-15 |
20110305641 | Compositions And Methods For Treatment Of Angiogenesis-Associated Ocular Disorders - The invention provides methods and compositions for identifying and quantifying pathological changes on the retina. | 2011-12-15 |
20110305642 | MICRONUTRIENT SUPPLEMENT - A micronutrient supplement the supplement being characterized by having at least two types of distinct dosage units wherein said distinct dosage units which physically separate nutritional, vitamin or mineral supplements which are known or proven to be negatively interacting when co-mingled or co-administered, the distinct dosage units being designed to be taken at a predetermined time interval. | 2011-12-15 |
20110305643 | High Oil-Content Emollient Aerosol Foam Compositions - Described herein are high oil-content emulsions and compositions for the treatment of inflammatory skin disorders. The emulsions may be formulated as aerosol compositions. The aerosol propellant may be a hydrofluoroalkane propellant. The emulsions or compositions may comprise active agents, such as corticosteroids. Also described are methods of treating inflammatory skin disorders, comprising the step of applying to an affected area of a subject in need thereof a therapeutically-effective amount of an inventive emulsion or aerosol composition. | 2011-12-15 |
20110305644 | Wool Care Composition - The present invention relates to a wool care composition comprising pyrethroid insecticide, a copolymer and a solvent wherein the said copolymer binds with the solvent and pyrethroid insecticide. This composition can be an improved aerosol spray formulation for treating of pure or blended woollen clothing and textile, fur and feather lined garments and other keratinous items for protection or insect proofing from various types of insect pests both clothes moths and carpet beetles during their storage, transport and use. Wool care aerosol solution can be sprayed with pressurized container having either a propellant as ready-to-use aerosol or manually operated sprayers. The aerosol spray composition may also contain fragrance and solvent. The other components in the composition are at least one copolymer/emulsifier and/or dispersant. | 2011-12-15 |
20110305645 | CRYSTAL FORM OF GLYCOPYRRONIUM CHLORIDE - A new crystal form of threo glycopyrronium chloride is useful in pharmaceutical applications. | 2011-12-15 |
20110305646 | FATTY ACID MONOGLYCERIDE COMPOSITIONS - The present invention relates to a method of treating a fungal condition caused by | 2011-12-15 |
20110305647 | USE OF A POLYSACCHARIDE WHICH IS EXCRETED BY THE VIBRIO DIABOLICUS SPECIES FOR THE REGENERATION AND PROTECTION OF THE PERIODONTIUM - The invention relates to the use of a polysaccharide which is excreted by the | 2011-12-15 |
20110305648 | Methods of Preparing Personal Care Compositions - Disclosed herein are embodiments of a method of predicting and adjusting the viscosity of consumer product compositions prior to their final formulation. The prediction aides the determination of the amount of a viscosity modifier to introduce in the manufacture of the final formulation to ensure the compositions have viscosities that satisfies consumer preferences, among other things. | 2011-12-15 |
20110305649 | High Humectant High Internal Phase Emulsion - A high humectant high internal phase emulsion is described. The emulsion has a high content of humectant and less than about 70% by weight water in the internal phase. The emulsion yields excellent moisturizing results when applied and is not sticky during or after application. | 2011-12-15 |
20110305650 | STABILIZATION OF COSMETIC COMPOSITIONS - Disclosed is the Use of UV absorbers selected from (a | 2011-12-15 |
20110305651 | SUNLESS TANNING COMPOSITIONS WITH NUCLEOPHILE FUNCTIONALIZED SULFONIC ACIDS - Sunless tanning compositions with nucleophile functionalized sulfonic acids are described. The compositions are stable and result in excellent tanning results when sunless tanning agents like 1,3-dihydroxy-2-propanone are used. | 2011-12-15 |
20110305652 | Anionic Surfactant Stable Cocoamide Monoethanolamine (CMEA) Composition - Disclosed herein is a composition containing liquid high activity micellar or lamellar phase liquid crystals of cocamide monoethanolamine (CMEA) and a detersive surfactant. The composition of the invention can be added to any personal care composition to form a personal care product and enable CMEA blending at room temperature. Also disclosed herein are methods for making the high activity CMEA micellar or lamellar phase liquid crystal composition. | 2011-12-15 |
20110305653 | PERSONAL CARE COMPOSITIONS WITH ETHYLENE ACRYLIC ACID COPOLYMER AQUEOUS DISPERSIONS - Described are personal care compositions, comprising an aqueous dispersion comprising an ethylene acrylic acid copolymer and a least one cosmetically acceptable surfactant, emollient, or cosmetic active. | 2011-12-15 |
20110305654 | ANHYDROUS PETROLEUM JELLY/ELASTOMER-FREE DEPIGMENTING COMPOSITIONS COMPRISING A SOLUBILIZED PHENOLIC COMPOUND - Novel dermatological depigmenting compositions, especially for topical application, contain as pharmaceutical active agents a dissolved phenolic compound, formulated as anhydrous compositions free of petroleum jelly and free of elastomer. | 2011-12-15 |
20110305655 | MOISTURIZING AND SHINE-IMPARTING EMULSION LIP COMPOSITIONS - The present invention is directed to an emulsion lip composition, in solid or stick form, containing: (a) at least one polyamine; (b) an oil-soluble polar modified polymer; (c) water; (d) at least one non-volatile solvent capable of solubilizing the oil-soluble polar modified polymer; and (e) at least one colorant. | 2011-12-15 |
20110305656 | Aqueous fragrancing composition comprising at least one volatile linear alkane; fragrancing process - The present invention relates to an anhydrous fragrancing composition free of C | 2011-12-15 |
20110305657 | Cooling Mixtures with an enhanced cooling effect of 5-methyl-2-(propane-2-yl)cyclohexyl-N-ethyloxamate - The invention relates to a cooling mixture comprising or consisting of 5-methyl-2-(propane-2-yl)cyclohexyl-N-ethyloxamate and one, two, three or more certain polyols. It further relates to a cosmetic composition comprising such a cooling mixture or to a sanitary article comprising such a cooling mixture. The invention also relates to the use of certain polyols for enhancing the cooling effect of 5-methyl-2-(propane-2-yl)cyclohexyl-N-ethyloxamate on the skin or a mucous membrane, a method for generating an enhanced cooling effect of 5-methyl-2-(propane-2-yl)cyclohexyl-N-ethyloxamate on the skin or a mucous membrane as well as a method for generating a corresponding cooling mixture. | 2011-12-15 |
20110305658 | LENGTHENING MASCARA COMPOSITION - The present invention is directed to a lengthening and smudge proof mascara composition for making up eye lashes having: (a) at least one alkyl ethoxylated polymer wax; (b) at least one oil soluble polar modified polymer; (c) at least one oil soluble high carbon polar modified polymer; (d) water; (e) at least one non-volatile oil capable of solubilizing the polar modified polymers; (f) optionally, at least one volatile solvent; and (g) optionally, at least one colorant, and wherein the composition does not require fibers to be dispersed therein. | 2011-12-15 |
20110305659 | FRESHENING COMPOSITIONS COMPRISING MALODOR BINDING POLYMERS AND MALODOR CONTROL COMPONENTS - Freshening compositions comprising a malodor binding polymer, malodor control components, and an aqueous carrier; and methods thereof are provided. In some embodiments, the freshening composition comprises a homopolymeric polyethylenimine having a molecular weight of about 1,000 to about 2,000,000 and a mixture of volatile aldehydes. Such freshening compositions may be used to reduce malodor and/or microbes on inanimate surfaces or in the air. | 2011-12-15 |
20110305660 | OMEGA-FUNCTIONALIZED POLYMERS, JUNCTION-FUNCTIONALIZED BLOCK COPOLYMERS, POLYMER BIOCONJUGATES, AND RADICAL CHAIN EXTENSION POLYMERIZATION - Polymeric compounds having spatially controlled bioconjugation sites are described. Functionalization is achieved by selective co-terminal chain extension of polymer chains by radical polymerization, such as reversible addition-fragmentation chain transfer (RAFT) polymerization. | 2011-12-15 |
20110305661 | Carbazole Compounds and Therapeutic Uses of the Compounds - Compounds of the general structural formula (I) and (II) and use of the compounds and salts and hydrates thereof, as therapeutic agents are disclosed. Treatable diseases and conditions include cancers, inflammatory diseases and conditions, and immunodeficiency diseases. | 2011-12-15 |
20110305662 | METHODS OF TREATING IMMUNODEFICIENCY VIRUS INFECTION - The present disclosure provides methods and compositions for reducing the reservoir of latent immunodeficiency virus in an individual, and for treating an immunodeficiency virus infection in an individual. | 2011-12-15 |
20110305663 | SERUM ALBUMIN BINDING MOLECULES - The present invention relates to an antibody-like protein based on the tenth fibronectin type III domain ( | 2011-12-15 |
20110305664 | NOVEL VACCINES AGAINST MULTIPLE SUBTYPES OF INFLUENZA VIRUS - An aspect of the present invention is directed towards DNA plasmid vaccines capable of generating in a mammal an immune response against a plurality of influenza virus subtypes, comprising a DNA plasmid and a pharmaceutically acceptable excipient. The DNA plasmid is capable of expressing a consensus influenza antigen in a cell of the mammal in a quantity effective to elicit an immune response in the mammal, wherein the consensus influenza antigen comprises consensus hemagglutinin (HA), neuraminidase (NA), matrix protein, nucleoprotein, M2 ectodomain-nucleo-protein (M2e-NP), or a combination thereof. Preferably the consensus influenza antigen comprises HA, NA, M2e-NP, or a combination thereof. The DNA plasmid comprises a promoter operably linked to a coding sequence that encodes the consensus influenza antigen. Additionally, an aspect of the present invention includes methods of eliciting an immune response against a plurality of influenza virus subtypes in a mammal using the DNA plasmid vaccines provided. | 2011-12-15 |
20110305665 | PEGYLATED INTERLEUKIN-10 - Interleukin-10 (IL-10) conjugated via a linker to one or more polyethylene glycol (PEG) molecules at a single amino acid residue of the IL-10, and a method for preparing the same, are provided. The method produces a stable mono-pegylated IL-10, which retains IL-10 activity, where pegylation is selective for the N-terminus on one subunit of IL-10 with little or no formation of monomeric IL-10. The method also provides a substantially homogenous population of mono-PEG-IL-10. | 2011-12-15 |
20110305666 | COMPOUNDS, COMPOSITIONS AND METHODS FOR TREATING OR PREVENTING PNEUMOVIRUS INFECTION AND ASSOCIATED DISEASES - Compounds, compositions and methods are provided for the prophylaxis and treatment of infections caused by viruses of the Pneumovirinae subfamily of Paramyxoviridae and diseases associated with such infections. | 2011-12-15 |
20110305667 | USE OF A DEAD-BOX RNA HELICASE FOR INDUCING CYTOKINE PRODUCTION - The invention relates to the use of a DEAD-box RNA helicase from a yeast, a mammal, | 2011-12-15 |
20110305668 | METHODS FOR USING INTERFERON GAMMA TO ABSORB FLUID FROM THE SUBRETINAL SPACE - Particular aspects of the invention provide methods for decreasing the amount of fluid present in the subretinal space of the eye by administering interferon gamma to the basolateral side of the retinal pigment epithelium. Adverse ocular conditions associated with the accumulation of fluid in the subretinal space can be treated by administering an amount of interferon gamma to the basolateral side of the retinal pigment epithelium effective to remove excess fluid from the subretinal space. | 2011-12-15 |
20110305669 | PROCESS FOR THE PREPARATION OF GLYCOSYLATED INTERFERON BETA - The present invention relates to a process for the production of interferon beta, and to an interferon beta composition having a unique glycosylation pattern. | 2011-12-15 |
20110305670 | NUCLEIC ACID ENCODING FUSION POLYPEPTIDES THAT PREVENT OR INHIBIT HIV INFECTION - The present invention is directed to an isolated nucleic acid molecule encoding a fusion polypeptide the expression of which in cells is capable of blocking the entry of HIV-1 into host cells and methods of using the nucleic acid molecule. | 2011-12-15 |
20110305671 | Cell Compositions and Methods for Hair Follicle Generation - The application describes a method of generating a hair follicle, comprising administering a composition comprising epidermal matrix cells, dermal papilla cells, dermal sheath cells and outer root sheath cells to the scalp of a mammal. The composition may optionally be administered with a hair growth agent and/or a carrier. The application also describes a composition comprising epidermal matrix cells, dermal papilla cells, dermal sheath cells and outer root sheath cells and the use of the composition to generate hair follicles. | 2011-12-15 |
20110305672 | COMPOSITIONS FOR MESODERM DERIVED ISL1+ MULTIPOTENT CELLS (IMPs), EPICARDIAL PROGENITOR CELLS (EPCs) AND MULTIPOTENT CD56C CELLS (C56Cs) AND METHODS OF PRODUCING AND USING SAME - The present invention relates to inter alia, methods for the generation and maintenance of Mesoderm-derived ISL1+ Multipotent Progenitors (IMPs), the production of a number of pluripotent cells including and epicardial pluripotent cells (EPCs) and using these cells to produce endothelial cells, cardiomyocytes, smooth muscle cells, vascular cells and other cells and related methods as otherwise disclosed herein. The invention also relates to compositions comprising a population of cells. | 2011-12-15 |
20110305673 | COMPOSITIONS AND METHODS FOR TISSUE REPAIR - The invention features compositions comprising mesenchymal stem cells or multipotent stromal cells, agents secreted by such cells in culture, and methods featuring such cells for the repair or regeneration of a damaged tissue or organ. The present invention is based, at least in part, on the discovery that agents secreted by bone marrow mesenchymal stem cells or multipotent stromal cells (MSCs) were useful for the treatment or prevention of tissue damage related to ischemic injury (e.g., cerebral or cardiac ischemia). | 2011-12-15 |
20110305674 | Pathways to Generate Hair Cells - This disclosure relates to methods and compositions for modulating (e.g., increasing) Atoh1 activity (e.g., biological activity) and/or expression (e.g., transcription and/or translation) in vivo and/or in vitro, e.g., in a biological cell and/or in a subject. The methods and compositions described herein can be used in the treatment of diseases and/or disorders that would benefit from increased Atoh1 expression in a biological cell. | 2011-12-15 |
20110305675 | METHODS FOR EXPANSION OF HEMATOPOIETIC STEM AND PROGENITOR CELLS - Described herein are methods and compositions for expanding hematopoietic stem and progenitor cells (HSPC) ex vivo and in vivo, and methods and compositions for transplanting HSPCs and treatment of anemia in a human subject. HSPCs are expanded in the presence of an inhibitor of serine threonine kinase 38 (STK38), wherein said inhibitor is preferably an RNAi agent. | 2011-12-15 |
20110305676 | METHODS FOR ENHANCING HEMATOPOIETIC STEM/PROGENITOR CELL ENGRAFTMENT - Described herein are methods for enhancing engraftment of hematopoietic stem and progenitor cells using compounds identified using a zebrafish model of hematopoietic cell engraftment. The compounds can be used to treat hematopoietic stem cells ex vivo prior to transplantation of the cells. Alternatively, the compounds can be administered to an individual undergoing cell transplantation. | 2011-12-15 |
20110305677 | HUMAN EMBRYONIC STEM CELL CULTURES, AND COMPOSITIONS AND METHODS FOR GROWING SAME - Human pluripotential embryonic stem cell cultures are provided, as are human feeder cells useful for growing the human embryonic stem cells, conditioned medium obtained from cultures of the human feeder cells, and factors derived from the conditioned medium. Also provided are methods of growing human embryonic stem cells in the presence of the human feeder cells, the conditioned medium, the factors derived from the conditioned medium, or a combination thereof. In addition to the human embryonic stem cell cultures grown according to such methods, isolated human embryonic stem cells obtained from such human embryonic stem cell cultures are provided, as are methods of using such isolated cells. | 2011-12-15 |
20110305678 | USE OF MESENCHYMAL STEM CELLS FOR TREATING GENETIC DISEASES AND DISORDERS - A method of treating a genetic disease or disorder such as, for example, cystic fibrosis, Wilson's disease, amyotrophic lateral sclerosis, or polycystic kidney disease, in an animal comprising administering to said animal mesenchymal stem cells in an amount effective to treat the genetic disease or disorder in the animal. | 2011-12-15 |
20110305679 | Blood-Cholesterol-Lowering Strain of Lactobacillus Delbrueckii - The invention relates to a novel strain of | 2011-12-15 |
20110305680 | Composition Containing Osteopontin for Differentiating Natural Killer Cell as an Active Ingredient and a Method of Differentiation Using Thereof - The present invention relates to a composition for differentiating natural killer cells comprising osteopontin (OPN) as an active ingredient and a method for differentiation using the same. More precisely, osteopontin of the present invention accelerates differentiation of natural killer cells from hematopoietic stem cells and increases cytotoxic activity of natural killer cells, so that it can be effectively used as a composition for differentiating natural killer cells. OPN of the present invention regulates differentiation of natural killer cells capable of killing cancer cells, so that it can be effectively used for the treatment of cancer. | 2011-12-15 |
20110305681 | TOPICAL HAIR CARE FORMULATION AND METHOD OF MAKING - A topical hair care formulation and method of making includes combining herbal powders to form a herbal powder mixture. The herbal powder mixture is steeped in an amount of carrier oil for a period of time to form an infused oil. A portion of an amount of olive oil is combined with an amount of biotin and an amount of an organosulfur compound to form a natural mixture. A remainder of the amount of olive oil is combined with the infused oil. An amount of jojoba oil is combined with the infused oil. An amount of rosemary oil is combined with the infused oil. An amount of lavender oil is combined with the infused oil. The natural mixture is combined with the infused oil. The infused oil is settled for a period of time to form the topical hair care formulation. | 2011-12-15 |
20110305682 | Compositions and Methods for Treating S. Pneumonia Infection - The present invention relates to novel compounds that are useful for inhibition and prevention of pathogen cell adhesion and cell adhesion-mediated pathologies. This invention also relates to pharmaceutical formulations comprising these compounds and methods of using them for inhibition and prevention of pathogen cell adhesion and cell adhesion-mediated pathologies. The compounds and pharmaceutical compositions of this invention can be used as therapeutic or prophylactic agents. They are particularly well-suited for treatment of infectious diseases. | 2011-12-15 |
20110305683 | Stabilization Of Perhydrolases - Disclosed herein is a method for stabilization of the perhydrolase activity of the CE-7 esterase in a formulation with a carboxylic acid ester that employs the addition of a buffering agent, substantially undissolved, to the mixture of the CE-7 esterase and the carboxylic acid ester. Further, disinfectant and laundry care formulations comprising the peracids produced by the processes described herein are provided. | 2011-12-15 |
20110305684 | IMMUNOSTIMULATORY PROPERTIES OF OLIGONUCLEOTIDE-BASED COMPOUNDS COMPRISING MODIFIED IMMUNOSTIMULATORY DINUCLEOTIDES - The invention relates to the therapeutic use of oligonucleotides as immunostimulatory agents in immunotherapy applications. More particularly, the invention provides an immunostimulatory oligonucleotides for use in methods for generating an immune response or for treating a patient in need of immunostimulation. The immunostimulatory oligonucleotides of the invention preferably comprise novel purines. The immunostimulatory oligonucleotides according to the invention further comprise at least two oligonucleotides linked at their 3′ ends, internucleoside linkages or functionalized nucleobase or sugar to a non-nucleotidic linker, at least one of the oligonucleotides being an immunostimulatory oligonucleotide and having an accessible 5′ end. | 2011-12-15 |
20110305685 | SUPRAMOLECULAR APPROACH FOR PREPARATION OF SIZE CONTROLLABLE NANOPARTICLES - A supramolecular approach has been developed for preparation of size-controllable nanoparticles, from three different molecular building blocks. | 2011-12-15 |
20110305686 | THERAPIES FOR CHRONIC RENAL FAILURE USING ONE OR MORE INTEGRIN ANTAGONISTS - The present invention provides methods for the treatment, and pharmaceuticals for use in the treatment, of mammalian subjects in, or at risk of chronic renal failure, or at risk of a need for renal replacement therapy. The methods involve the administration of certain integrin antagonists. | 2011-12-15 |