50th week of 2008 patent applcation highlights part 45 |
Patent application number | Title | Published |
20080306254 | Process for Modification of Biopolymers - A biopolymer thinning process is provided comprising the steps of (a) mixing a biopolymer substrate with a thinning agent and an alkalizing agent; and (b) drying the mixture of step (a), wherein the thinning agent consists of one or more hypochlorites; and step (a) is carried out at a neutral to alkaline pH and does not involve any artificial heating. | 2008-12-11 |
20080306255 | Method for Selective Separation of Cellulosic Polymer and Apparatus Therefor - A matter to be treated which contains a cellulosic polymer is heated in a solvent in the presence of an acid catalyst, to thereby selectively decompose the cellulosic polymer to a fine powder. Furthermore, a matter to be treated which contains a cellulosic polymer is reacted with an esterification agent in the presence of an acid catalyst, to thereby selectively dissolve or disperse the cellulosic polymer. In either method, the treated matter other than the cellulosic polymer does not change in state but remains solid, so that both can be easily separated by sieving or solid-liquid separation. | 2008-12-11 |
20080306256 | Salts in the Preparation of Cephalosporin Antibiodies - The present invention relates to an improved process for the preparation of cephalosporin antibiotics of formula (I). The present invention also provides new salts of compound of formula (II) and a process for the preparation of these new salts, where n=0.5 to 2. The present invention also provides a process for the preparation of compound of formula (I) using the new salts of formula (II). | 2008-12-11 |
20080306257 | Syntheses and Preparations of Narwedine and Related Novel Compounds - The present invention relates to a process for preparing racemic narwedine (which can be can be kinetically resolved) to yield (−)-narwedine and which is the biogenic precursor of (−)-galanthamine) and the use thereof as a starting material for producing (−)-galanthamine. The invention further includes processes for preparing (−)-galanthamine and (−)-galanthamine hydrobromide, as well as related novel compounds. | 2008-12-11 |
20080306258 | Cyclopropane compounds and pharmaceutical use thereof - The present invention provides a compound having aggrecanase inhibitory activity and MMP-13 inhibitory activity, and useful as a therapeutic agent for osteoarthritis, rheumatoid arthritis and the like, more specifically, a cyclopropane compound of formula (1): | 2008-12-11 |
20080306259 | HYDROXYLATION OF BETA-DICARBONYLS WITH ZIRCONIUM CATALYSTS - The present invention pertains to a process for preparing a compound of Formula I that is achiral, racemic or enantiomerically enriched at the hydroxylation center indicated by * | 2008-12-11 |
20080306260 | Method for Producing Aryl Amines, Aryl Ethers and Aryl Thioethers - The invention relates to a method for producing aryl or heteroaryl amines, ethers or thioethers (III) by cross-coupling primary or secondary amities, alcohols or thioalcohols with substituted aryl or heteroaryl compounds (I) in the presence of a Brønsted base and a catalyst or a pre-catalyst containing a) a transition metal, a complex, a salt, or a compound of a transition metal from the group V, Mn, Fe, Co, Ni, Rh, Pd, Ir, Pt, and b) at least one sulfonated phosphane ligand in a solvent or a solvent mixture corresponding to Scheme 1 wherein Hal represents fluorine, chlorine, bromine, iodine, alkoxy, trifluoromethane sulfonate, nonafluorotrimethyl-methane sulfonate, methane sulfonate, 4-nitrobenzene sulfonate, benzene sulfonate, 2-naphthalene sulfonate, 3-nitrobenzene sulfonate, 4-nitrobenzene sulfonate, 4-chlorobenzene sulfonate, 2,4,6-triisopropylbenzene sulfonate or any other sulfonate, and X represents O, S or NR″. The invention also relates to novel phosphane ligands. | 2008-12-11 |
20080306261 | Process For Treating a Reaction Mixture Comprising Alkoxycarbonylaminotriazine - Processes comprising: providing an alkanolic reaction mixture, the alkanolic reaction mixture comprising: at least one alkoxycarbonylaminotriazine; at least one carbonic ester; at least one C | 2008-12-11 |
20080306262 | Novel Compound - A compound of formula (I) and pharmaceutically acceptable salts or solvates thereof | 2008-12-11 |
20080306263 | Process For The Preparation Of Optically Pure Tetrahydropterins And Derivatives, And Specifically Of Optically Pure Tetrahydrofolic Acid And Derivatives Thereof, By Stereospecific Hydrogenation - Process for the preparation of tetrahydropterin and tetrahydropterin derivatives by hydrogenating pterin and pterin derivatives with hydrogen in the presence of a hydrogenating catalyst, in which the hydrogenation is carried out in a polar reaction medium and metal complexes that are soluble in the reaction medium are employed as the hydrogenation catalysts. The process is suited to the hydrogenation, particularly asymmetric hydrogenation, of folic acid, folio acid salts, folio acid esters, folio acid ester salts or dihydroforms thereof, with the proviso that in the event of using folic acid, carboxylic acid salts thereof or dihydroforms thereof the reaction medium is aqueous, and in the event of using folic acid esters, folic acid ester salts or dihydroforms thereof the reaction medium is an alcohol. The process opens up straightforward access to achiral and chiral pterin derivatives. | 2008-12-11 |
20080306264 | Cycloolefin Phosphine Ligands and Their Use in Catalysis - The present invention concerns novel bidentante optionally N-containing P-ligands of general Formula (I) embracing a two-ring-system and processes for synthesizing them, transition metal complexes of these compounds and their use as catalysts. | 2008-12-11 |
20080306265 | PREPARATION OF OXYCODONE - A method of purifying oxycodone or a salt thereof includes the steps of:
| 2008-12-11 |
20080306266 | Process for Preparing 2-Methyl-1-(2-Methylpropyl)-1H-Imidazo[4,5-C][1,5]Naphthyridin-4-Amine - The invention provides various processes for preparing 2-methyl-1-(2-methylpropyl)-1H-imidazo[4,5-c][1,5]naphthyridin-4-amine. | 2008-12-11 |
20080306267 | METHOD FOR MAKING TETRABENAZINE COMPOUNDS - A method of preparing a tetrabenazine compound (TBZ compound) having structure I comprising the steps of reacting a nucleophilic alkenyl species with aldehyde compound II and oxidizing the resultant allylic alcohol to provide enone III. The protecting group P | 2008-12-11 |
20080306268 | Crystalline clopidogrel hydrobromide and processes for preparation thereof - Provided are crystalline forms of clopidogrel hydrobromide and processes for their preparation. | 2008-12-11 |
20080306269 | INTERMEDIATES USEFUL FOR MAKING TETRABENAZINE COMPOUNDS - A method of preparing a tetrabenazine compound (TBZ compound) having structure I comprising the steps of reacting a nucleophilic alkenyl species with aldehyde compound II and oxidizing the resultant allylic alcohol to provide enone III. The protecting group P | 2008-12-11 |
20080306270 | Process for the Preparation of a Leukotriene Antagonist and Intermediates Thereof - It comprises a preparation process of Montelukast from a new intermediate compound of formula (VI), which is previously prepared by reaction of the corresponding sulfonate with 1-(mercaptomethyl)cyclopropyl)methanol. Compound (VI) is reacted with a Grignard reactant to convert the ester group into a tertiary alcohol, followed by conversion of the primary alcohol into a sulfonate, substitution of the sulfonate group by a cyano group, and finally transforming the cyano compound to the carboxilic acid compound by a hydrolysis reaction to afford Montelukast. Montelukast can also be prepared by a hydrolysis reaction of the corresponding amide. It also comprises new intermediate compounds useful in such preparation process. | 2008-12-11 |
20080306271 | Novel Process for Production of Highly Pure Polymorph (I) Donepezil Hydrochloride - The present invention provides a novel, industrially realizable and economically preferable process for production of highly pure 1-benzyl-4-[(5,6-dimethoxy-1-indanon)-2-yl]methyl piperidine hydrochloride, i.e., donepezil hydrochloride shown in the following reaction scheme, in Polymorph (I) morphological crystal form. (I) In one of the key steps of the process, during the hydrogenation 5,6-dimethoxy 2-(pyridine-4-yhnethylene)indan- | 2008-12-11 |
20080306272 | ONE-POT METHODS FOR PREPARING CINNAMIDE DERIVATIVES - A compound represented by the following formula ( | 2008-12-11 |
20080306273 | Process for the Preparation of 1-Aminopiperidine Derivatives - The present invention relates to a process for the preparation of compounds of the general formula (I). | 2008-12-11 |
20080306274 | METHOD FOR PREPARING N-AMINOPIPERIDINE AND ITS SALTS - The invention concerns a novel method for preparing N-aminopiperidine of formula (I): | 2008-12-11 |
20080306275 | NOVEL HETEROARYL DERIVATIVE - A heteroaryl derivative of the formula (1): | 2008-12-11 |
20080306276 | FACILE SYNTHESIS OF A SERIES OF LIQUID CRYSTALLINE 2-(4'-ALKOXYPHENYL)-5-CYANOPYRIDINES - The invention relates to a facile synthesis of a series of 2-(4′-alkoxyphenyl)-5-cyanopyridine liquid crystal compounds which are represented by the following formula (I): | 2008-12-11 |
20080306277 | Process for Preparation of Chiral Amlodipine Gentisate - The present invention relates to a process for the preparation of optically pure amlodipine gentisate, more particularly to a continuous process for the preparation of optically pure amlodipine gentisate with good yield and high optical purity. The processes can be preformed by first reacting racemic (R,S)-amlodipine and optically pure O,O′-dibenzoyltartaric acid in the presence of a solvent including isopropanol to prepare (R)- or (S)-amlodipine dibenzoyltartarate diastereomer or a solvate thereof, treating the prepared amlodipine diastereomeric salt or a solvate thereof with a base and then finally adding gentisic acid. | 2008-12-11 |
20080306278 | PROCESS - An improved process for preparing arylethanoldiamines is described. Compounds of this type are known to be useful as agonists at atypical beta-adrenoceptors (also known as beta-3-adrenoceptors). | 2008-12-11 |
20080306279 | Synthesis Intermediates Useful For Preparing Zolmitriptan - In particular, this invention relates to the synthesis intermediates (IV), (V), (VI) and (VIII) useful for preparing zolmitriptanzohnitriptan or a pharmaceutically acceptable salt thereof, which includes a) Preparation of the diazonium salt of the aniline hydrochloride (II); followed by reduction and acidification to give hydrazine (III); b) In situ Reaction of the hydrazine hydrochloride (III) with α-keto-δ-valerolactone, to give the hydrazone (IV); c) Fischer indole synthesis of the hydrazone (IV), to give the pyranoindolone of formula (V); d) Transesterification of the pyranoindolone (V) to provide the compound (VI), in which R means a straight or branched C1-C4 alkyl; e) Conversion of the hydroxyl group of the compound (VI) into dimethylamino to give the indolecarboxylate (VII), in which R means a straight or branched C1-C4 alkyl; f) Saponification of the 2-carboalkoxy group of the compound (VII), to provide indolecarboxylic acid (VIII); g) Decarboxylation of the indolecarboxylic acid (VIII), to provide zolmitriptan and, eventually, to provide a pharmaceutically acceptable salt thereof. | 2008-12-11 |
20080306280 | Novel process for the preparation of phenylcarbamates - This invention relates to a process for the preparation of an aminoalkyl phenyl carbamate compound of formula 1, | 2008-12-11 |
20080306281 | NOVEL COMPOUNDS COMPRISING A THIOCARBONYL-SULFANYL GROUP WHICH CAN BE USED FOR THE RADICAL SYNTHESIS OF ALPHA-PERFLUOROALKYLAMINE COMPOUNDS - The invention relates to compounds having the general formula (I), the method of preparation thereof and the use thereof in organic radical synthesis. The invention also relates to compounds having the formula (II), the method of preparation thereof and a method for preparing compounds having the formula (VIII). | 2008-12-11 |
20080306282 | Novel Forms of [R-(R*,R*)]-2-(4-Fluorophenyl)-Beta,Delta-Dihydroxy-5-(1-Methylethyl)-3-Phenyl-4-[(Phenylamino)Carbonyl]-1H-Pyrrole-1-HeptanoicAcid Calcium Salt (2:1) - Novel forms of [R—(R*,R*)]-2-(4-fluorophenyl)-β,δ-dihydroxy-5-(1-methylethyl)-3-phenyl-4-[(phenylamino)carbonyl]-1H-pyrrole-1-heptanoic acid hemi calcium salt designated Form XX, Form XXI, Form XXII, Form XXIII, Form XXIV, Form XXV, Form XXVI, Form XXVII, Form XXVIII, Form XXIX, and Form XXX, characterized by their X-ray powder diffraction, solid-state NMR, and/or Raman spectroscopy are described, as well as methods for the preparation and pharmaceutical composition of the same, which are useful as agents for treating hyperlipidemia, hypercholesterolemia, osteoporosis, benign prostatic hyperplasia (BPH) and Alzheimer's disease. | 2008-12-11 |
20080306283 | Process For Production of Aralkyloxypyrrolidine Derivative - The present invention provides a process for producing a 3-aralkyloxypyrrolidine derivative which is important for production of pharmaceutical products and the like. In the present invention, a N-protected-3-hydroxypyrrolidine is converted into a N-protected-3-aralkyloxypyrrolidine by allowing an aralkyl halide to act in the presence of a base and at least one of a metal halide and a phase-transfer catalyst followed by deprotecting a N-protecting group to convert it to a 3-aralkyloxypyrrolidine derivative and subsequently treating the derivative in a solvent containing a polar solvent, thereby obtaining the 3-aralkyloxypyrrolidine derivative as a crystal. According to the present invention, a 3-aralkyloxypyrrolidine derivative of high purity can be produced conveniently and efficiently on an industrial scale. | 2008-12-11 |
20080306284 | Lipase Inhibitors - The present invention provides lipase inhibitors containing dimers having an epigallocatechin gallate (EGCG) unit derived from teas as well as foods and beverages and medicines containing said inhibitors. More specifically, the present invention provides lipase inhibitors containing at least one of proanthocyanidins represented by the formula: | 2008-12-11 |
20080306285 | Heat-Labile Prodrugs - Disclosed herein are heat-labile prodrugs, their preparation and uses. | 2008-12-11 |
20080306286 | Isolation, Purification and Synthesis of Procyanidin B2 and Uses Thereof - Methods for the synthesis, isolation, and purification of procyanidin B2 are disclosed. The synthetic methods utilize epicatechin as a starting material and produce procyanidin B2 in high yields. The isolation methods extract procyanidin B2 from a sample of bark powder from plant matter of the genus | 2008-12-11 |
20080306287 | Process for Preparing Tetrahydropyran-4-Carboxylic Acid Compound - The present invention is to provide a process for preparing tetrahydropyran-4-carboxylic acid represented by the formula (1): | 2008-12-11 |
20080306288 | Method for Producing Olefin Oxides and Peroxides, Reactor and the Use Thereof - A process for reactions with or to form peroxidic compounds in a wall reactor whose reaction space has a specific material coating is described. | 2008-12-11 |
20080306289 | CATALYST COMPOSITION, A PROCESS FOR PREPARING THE CATALYST COMPOSITION AND A USE OF THE CATALYST COMPOSITION - A catalyst composition comprising a support having a surface area of at least 500 m | 2008-12-11 |
20080306290 | Process for Epoxidizing Propene - The present invention provides a process for the epoxidation of propene which comprises reacting propene with hydrogen peroxide in the presence of methanol as solvent and a titanium zeolite catalyst, the process further comprising separating propylene oxide from the reaction mixture to obtain a mixture comprising methanol, water, at least one carboxylic acid and at least one carbonyl compound, wherein the at least one carboxylic acid is at least partially neutralized, said process optionally comprising a hydrogenation stage. | 2008-12-11 |
20080306291 | START-UP OF HIGH SELECTIVITY CATALYSTS IN OLEFIN OXIDE PLANTS - A method to achieve a controlled start-up temperature of an expoxidation process which exceeds the maximum achievable temperature of the epoxidation reactor relative to using an external heat source. The method of the present invention employs an oxidation reaction within the reactor to bring the temperature of the reactor to a temperature that is suitable for conditioning a high selectivity catalyst. The method of the present invention includes first bringing a reactor including a high selectivity catalyst to a first temperature using the external heat source to the reactor, while staying within the reactor design limitations and maintaining a gas flow to the reactor that is within 25 to 100% of the design rates. Once the reactor has achieved the first temperature, at least an olefin, e.g., ethylene, and then oxygen are introduced to the reactor feed gas. The olefin and oxygen concentrations are adjusted to have a heat of reaction that will allow raising the reactor gas flow to 100% of design and then have sufficient heat of reaction to raise the reactor temperature to a second temperature which is greater than the first temperature and greater than the temperature of the reactor achievable by the external heat source. | 2008-12-11 |
20080306292 | Synthesis of (S)-(+)-3-(aminomethyl)-5-methyl hexanoic acid - Provided are syntheses of (S)-(+)-3-(aminomethyl)-5-methylhexanoic acid, (S)-Pregabalin via a chiral intermediate of the following formula 4 | 2008-12-11 |
20080306293 | Production Process of Alkoxy-Titanium Complex - The present invention provides a process for producing an alkoxy-titanium complex of formula (2) by reacting a titanium halide complex of formula (1) with an alkaline earth metal alkoxide: | 2008-12-11 |
20080306294 | Silylated polycarbonate polymers, method of making, and articles - A silylated dihydroxy aromatic compound of the formula (1a); | 2008-12-11 |
20080306295 | Method and Device for the Sulfonation or Sulfation of Sulfonatable or Sulfatable Organic Substances and for Performing Faster, Strongly Exothermic Gas/Liquid Reactions - A method and a device for the sulfonation or the sulfation of organic liquid raw materials with an S0 | 2008-12-11 |
20080306296 | Process for the resolution of racemic verapamil - A new process is described for the resolution of racemic verapamil, which allows the desired enantiomer to be obtained in high yields and with high enantiomeric purity. The process uses optically active 2,3-bis[(2-fluorobenzoyl)oxy]butanedioic acid as the resolving agent, and a water/dimethylformamide or water/acetonitrile or water/methanol mixture, as the reaction solvent. | 2008-12-11 |
20080306297 | NOVEL 2-CYANO-3(HALO)ALKOXY-BENZENESULFONAMIDE COMPOUNDS FOR COMBATING ANIMAL PESTS - Novel 2-cyano-3-(halo)alkoxy-benzenesulfonamide compounds for combating animal pests | 2008-12-11 |
20080306298 | Method for Manufacturing Palladium-Containing Catalyst - The present invention provides: a palladium-containing supported catalyst which is used for producing an α,β-unsaturated carboxylic acid from an olefin or an α,β-unsaturated aldehyde in high selectivity; a method for manufacturing the catalyst; and a method for producing an α,β-unsaturated carboxylic acid in high selectivity. In particular, the present invention resides in a method for manufacturing a palladium-containing supported catalyst for producing an α,β-unsaturated carboxylic acid from an olefin or an α,β-unsaturated aldehyde, comprising the step of reducing palladium oxide contained in a catalyst precursor wherein at least the palladium oxide is supported on a carrier. By using such a palladium-containing supported catalyst, an α,β-unsaturated carboxylic acid is produced through liquid-phase oxidation of an olefin or an α,β-unsaturated aldehyde with molecular oxygen. | 2008-12-11 |
20080306299 | Method for the Production of Aminoalkane Acid Amides - The invention relates to a process for preparing aminoalkanamides by reacting cyanoalkanoic esters with a) ammonia or an amine and b) hydrogen in the presence of a catalyst, the reaction with component b) being started simultaneously or not later than a maximum of 100 minutes after commencement of the reaction of the cyanoalkanoic ester with component a). | 2008-12-11 |
20080306300 | Stepwise Execution of Exothermic Reactions with Participation of Carbocations - The invention relates to a method for carrying out reactions with participation of carbocations, whereby the initial most strongly exothermic phase of the reaction is carried out at high temperature (60 to 120° C.) and short residence time (1 to 30 seconds) in a microreactor and the subsequent less exothermic phases are carried out at optionally lower temperatures in two or more residence time units with longer residence times (1 to 30 seconds). | 2008-12-11 |
20080306301 | BROAD SPECTRUM ANTIMICROBIAL PURIFICATION MATERIALS AND METHODS FOR PURIFYING FLUIDS - An antimicrobial composition for use in water, air, and other fluid treatment applications is provided. The composition includes a biguanide dihydrate compound, such as a chlorhexidine dihydrate, which exhibits broad spectrum antimicrobial activity. | 2008-12-11 |
20080306302 | Processes for the Preparation of Tetrakis(F Aryl)Borate Salts - A process for the preparation of organic cation tetrakis( | 2008-12-11 |
20080306303 | CHRYSENES FOR DEEP BLUE LUMINESCENT APPLICATIONS - This disclosure relates to chrysene compounds with deep blue emission that are useful in electroluminescent applications. It also relates to electronic devices in which the active layer includes such a chrysene compound. | 2008-12-11 |
20080306304 | Method For Producing O-Alkylated Cyclic Aminoalcohols - A process for preparing O-alkylated amino alcohols of the formula (I) by reacting N-unsubstituted or N-monosubstituted amino alkoxide salts with alkyl halides, the amino alkoxide salts being formed by means of alkoxides | 2008-12-11 |
20080306305 | Process for Hydrogenating Nitriles to Primary Amines or Aminonitriles and Catalysts Suitable Therefor - A process for hydrogenating oligonitriles which have at least two nitrile groups in the presence of a catalyst which, before commencement of the hydrogenation, is pretreated by contacting with a compound A which is selected from alkali metal carbonates, alkaline earth metal carbonates, ammonium carbonate, alkali metal hydrogencarbonates, alkaline earth metal hydrogencarbonates, ammonium hydrogencarbonate, alkaline earth metal oxocarbonates, alkali metal carboxylates, alkaline earth metal carboxylates, ammonium carboxylates, alkali metal dihydrogen phosphates, alkaline earth metal dihydrogen phosphates, alkali metal hydrogen phosphates, alkaline earth metal hydrogen phosphates, alkali metal phosphates, alkaline earth metal phosphates and ammonium phosphate, alkali metal acetates, alkaline earth metal acetates, ammonium acetate, alkali metal formates, alkaline earth metal formates, ammonium formate, alkali metal oxalates, alkaline earth metal oxalates and ammonium oxalate. | 2008-12-11 |
20080306306 | Method for Producing 2-Adamantanol and 2-Adamantanone - The present invention is a process for producing 2-adamantanol and 2-adamantanone from 1-adamantanol, by using as a catalyst a substance comprising at least one kind of acid catalyst selected from Lewis acid(s) and solid acid(s) that coexist with at least one kind selected from the group consisting of carboxylic acids, sulfonic acids, and phosphoric acids, and provides a process suitable for mass production of 2-adamantanol and 2-adamantanone selectively with high efficiency without using sulfuric acid as a catalyst, thereby enabling laborsaving in waste acid treatment step and drastic reduction of the reaction time. | 2008-12-11 |
20080306307 | Friedel-Crafts Acylation Process in Ionic Liquids - A preparation process of aromatic ketones by a Friedel-Crafts acylation reaction in an ionic liquid of formula (I), in the absence of any other catalyst and/or solvent. In formula (I), [Q] | 2008-12-11 |
20080306308 | PROCESS FOR PREPARING FLUORINE-CONTAINING ALKOXYALKANE - A process for preparing a fluorine-containing alkoxyalkane represented by the general formula (1) R | 2008-12-11 |
20080306309 | Separation/Purification of Desflurane from Hydrogen Fluoride - An azeotrope comprising desflurane (CF | 2008-12-11 |
20080306310 | AVOIDANCE OF SOLIDS DEPOSITS IN DROPLET SEPARATORS BY METERING IN SUITABLE LIQUIDS - The present invention relates to a process for the avoidance of solids deposits in droplet separators (demisters) by metering in suitable liquids, in particular in the production of bis(4-hydroxyaryl)alkanes. | 2008-12-11 |
20080306311 | Method for Producing an Alpha-Chiral Chloromethyl Compound in a Pure Form - The present invention relates to a process for preparing a specific α-chiral chloromethyl compound in pure or enriched form by distillative removal of the compound mentioned from substance mixtures which comprise this compound and higher-boiling impurities. The α-chiral chloromethyl compound in question is present in crystalline form at room temperature and is a central intermediate for the preparation of a class of medicaments. | 2008-12-11 |
20080306312 | Process for Obtaining Alkoxides - Alkoxides are isolated by crystallization of an alcohol from a solution in the corresponding alcohol, with the alkoxide being crystallized out at a pressure of at least 3 bar abs. and a temperature of at least 120° C. | 2008-12-11 |
20080306313 | Non Thermal Plasma Method to Prepare [11C] Methyl Iodide From [11C] Methane and Iodine Methane and Iodine - A method and an apparatus for preparing [ | 2008-12-11 |
20080306314 | Hydrocarbyl- and Hydroxy-Substituted Aromatic Condensate - This invention relates to a composition containing: (a) a hydrocarbon fluid; and (b) a hydrocarbyl- and hydroxy-substituted aromatic condensate comprising the reaction product of: (1) at least 75 mole percent based on the total amount of (b)(1) and (b)(2) of a hydrocarbyl- and hydroxy-substituted aromatic compound wherein the hydrocarbyl substituent is a linear substituent containing 8 to 36 carbon atoms; (2) 0.001 to 25 mole percent based on the total amount of (b)(1) and (b)(2) of a hydrocarbyl- and hydroxy-substituted aromatic compound wherein the hydrocarbyl substituent is a branched substituent containing 8 to 20 carbon atoms; and (3) an amount of an aldehyde, ketone, or reactive equivalent thereof effective to condense (1) and (2) to form the hydro-carbyl- and hydroxy-substituted aromatic condensate. The invention further relates to method of preparing the condensate and its use as an additive in a crude oil, a liquid fuel or an oil of lubricating viscosity. | 2008-12-11 |
20080306315 | Metal-Organic Framework Catalysts and Their Use in Hydrocarbon Transformation - The invention relates to a porous heterogeneous catalyst material comprising frameworks of inorganic cornerstones connected by organic bridges, characterized in that as organic bridges are used ligands having a complexed catalytically active metal. The metals are preferably palladium and platinum. The ligands preferably contain nitrogen donor groups for complexing the catalytically active metal and carboxylate groups connecting to the inorganic cornerstones. | 2008-12-11 |
20080306316 | Process for Reacting an Aromatic Hydrocarbon in the Presence of Hydrogen - Processes comprising: providing a starting material comprising one or more aromatic hydrocarbons, and having an aromatic sulfur compound content and a total sulfur content; reducing the aromatic sulfur compound content and the total sulfur content in the starting material; and hydrogenating the one or more aromatic hydrocarbons in the presence of a supported ruthenium catalyst and hydrogen. | 2008-12-11 |
20080306317 | Aromatic Alkylation with Phosphorus-modified Zeolite catalyst - A catalyst is formed from a phosphorus-containing ZSM-5-type zeolite. The ZSM-5-type zeolite has a silica/alumina molar ratio of at least 200. The phosphorus-containing ZSM-5-type zeolite also has a phosphorus content of at least 8% by weight of zeolite and has multiple phosphorus species exhibited by at least two | 2008-12-11 |
20080306318 | Process for Producing Para-Xylene - A process for producing a PX-rich product comprises (a) separating a feedstock containing C | 2008-12-11 |
20080306319 | Oligomerisation - The application discloses novel processes for the oligomerisation of unsaturated hydrocarbons, and more specifically the use of selected ionic liquids in the oligomerisation of unsaturated hydrocarbons, which allows for selection of the oligomers formed. | 2008-12-11 |
20080306320 | Dehydrogenation and polymerization process - Process for the production of an isoprene containing rubber compound by dehydrogenation of an isoamylene containing feedstock supplied to a dehydrogenation reactor containing a particulate dehydrogenation catalyst comprising iron and potassium and having a pore diameter of at least 500 nanometers. The dehydrogenation reactor is operated at a temperature of at least 570° C. to dehydrogenate the isoamylene to produce isoprene. The product containing isoprene and unreacted isoamylene is recovered from the dehydrogenation reactor. Isoprene is polymerized to produce an isoprene containing rubber product. An unreacted feed component containing isoamylene is separated from the rubber product and recycled to the dehydrogenation reactor. | 2008-12-11 |
20080306321 | PROCESS FOR PRODUCING LIQUID HYDROCARBON WITH HYDROCRACKING CATALYST - Provided is a process and catalyst for hydrocracking paraffinic hydrocarbons which provides satisfactorily high cracking activity and middle distillate yield as well as the low pour point of the resulting gas oil all together. The catalyst of the present invention comprises a crystalline aluminosilicate, alumina-boria and a noble metal of Group VIII of the Periodic Table. | 2008-12-11 |
20080306322 | Everting gynecological brachytherapy applicator - An everting applicator for brachytherapy of body cavities such as the vagina has a flexible sleeve secured to a distal mandrel, both the sleeve and the mandrel having internal lumens. The flexible sleeve has a diverging opening at its distal end, preferably bell-shaped or cone-shaped, such that when the open end is pushed against the mouth of a vagina, the sleeve will evert back upon itself, progressively unrolling to an inside out configuration wherein, fully inserted, the sleeve is fully everted back over the exterior surface of the mandrel. A radiation source, isotopic or electronic, is then inserted into the mandrel lumen to commence a therapeutic irradiation procedure of tissues of the vagina. | 2008-12-11 |
20080306323 | Everting gynecological brachytherapy applicator and method - An everting applicator for brachytherapy of body cavities such as the vagina has a flexible sleeve secured to a distal mandrel, both the sleeve and the mandrel having internal lumens. The flexible sleeve has a diverging opening at its distal end, preferably bell-shaped or cone-shaped, such that when the open end is pushed against the mouth of a vagina, the sleeve will evert back upon itself, progressively unrolling to an inside out configuration wherein, fully inserted, the sleeve is fully everted back over the exterior surface of the mandrel. A radiation source, isotopic or electronic, is then inserted into the mandrel lumen to commence a therapeutic irradiation procedure of tissues of the vagina. | 2008-12-11 |
20080306324 | MAGNETIC JOINT IMPLANT - The application is directed to devices and methods where one or more magnetic or magnetizable implants provides therapeutic benefits to a patient. The implant may be useful for expanding the range of motion of joints or dynamically providing different responses to changing conditions in the body where the implant is placed. An electromagnet is placed on or in a bone on one side of a joint, and another electromagnet or magnetically active material is placed on or in a bone on the opposing side of the joint. The electromagnet may be continuously energized to relieve pressure in the joint space, or may be energized in response to forces applied to the joint. | 2008-12-11 |
20080306325 | METHOD AND APPARATUS FOR MAGNETIC INDUCTION THERAPY - An energy emitting apparatus for providing a medical therapy includes one or more energy generators, a logic controller electrically connected to the one or more energy generators, and one or more sensors for detecting electric conduction in a target nerve that are connected to the logic controller. The one or more energy generators produce energy focused on the target nerve upon receiving a signal from the logic controller, and the energy is varied by the logic controller according to an input provided by the one or more sensors. In one embodiment, the energy emitting apparatus is an apparatus for magnetic induction therapy that includes one or more conductive coils disposed in an ergonomic housing that produce a magnetic field focused on the target nerve upon receiving an electric current from the logic controller based on an input provided by the one or more sensors. | 2008-12-11 |
20080306326 | Drive Circuit For Magnetic Stimulation - The inventive technique includes devices and methods for generating a magnetic field. One such device may include an inductor for generating a magnetic field and a power source for providing power. Such a device may also include a semiconductor switching device that operatively couples the inductor and power source, wherein the semiconductor switching device directs power from the power source to the inductor to generate the magnetic field. | 2008-12-11 |
20080306327 | Apparatus Comprising a Drive Cable for a Medical Device - An article comprising a drive cable suitable for high-speed operation in an anatomy having small-radii bends is disclosed. The drive cables disclosed herein include one or more physical adaptations that enable them to be “tuned” to avoid large amplitude vibrations during operation. | 2008-12-11 |
20080306328 | DUCT FOR VENTRICULAR-ASSISTANCE DEVICE - A duct for carrying blood for ventricular-assistance devices (VADs) has a tubular body and an end having associated thereto a valve for enabling the flow of blood unidirectionally in the duct. The valve has an annular reinforcement, and the end of the duct is provided with a slot for receiving the annular reinforcement of the valve with the reinforcement in a retracted position in said slot. The aforesaid end and the aforesaid tubular body of the duct are provided with a continuous coating of haemocompatible material, such as a polyurethane. | 2008-12-11 |
20080306329 | Ventricular Assist Device - A manifold for accessing blood from a human blood vessel is disclosed which comprises a first and a second pathway intersecting with each other at an angle, the first pathway being configured to be completed embedded in the human blood vessel with the second pathway leading toward outside of the human blood vessel wherein the manifold is substantially retained by the human blood vessel alone. | 2008-12-11 |
20080306330 | SLEEPING MODE ACCESSORY - A device for inducing a target physiological state in a user may include a portable device including at least one receiver for receiving measurement data indicative of a current physiological state of the user, a processing unit for processing the received measurement data, at least one audio output unit and a memory, the processing unit being arranged to detect the current physiological state of the user by comparing the processed received measurement data to predefined data in the memory indicative of physiological states, wherein the processing unit is arranged to output audio data through the audio output unit depending on the detected current physiological state and to adjust the output of the audio data according to the target physiological state to be induced in the user. | 2008-12-11 |
20080306333 | Apparatus and Method for Endoscopic Surgical Procedures - Apparatus and method for performing surgical procedures within the mediastinum and within the pericardium include an endoscopic cannula having a transparent tip, and an endoscope for introduction into the mediastinum and optionally into the pericardium via a single subxiphoid incision. A cavity may be initially dilated for advancing the endoscopic cannula using a dilating tool that exerts a lateral-expansive force against surrounding tissue for evaluating the endoscopic cannula to be introduced into the mediastinum. Other surgical instruments are positioned through the endoscopic cannula to cut a flap of the pericardium as an opening through which other surgical apparatus may be introduced. The endoscopic cannula may be swept around selected regions of the heart through an aperture near the apex of the heart to facilitate placement of epicardial tacks about regions of the heart. | 2008-12-11 |
20080306334 | Endoscopic treatment tool - An endoscopic treatment tool includes a flexible sheath; an operating member inserted to the sheath so as to freely advance and retract; a treatment section disposed at the distal end of the operating member that protrudes and retracts from the sheath; and an operator section connected to the proximal end of the operating member including a sliding member which makes the operating member advance and retract. The endoscopic treatment tool includes the operating member consisting of a member which increases its rigidity by compression, and a member which compresses the operating member. Therefore a sufficient incision or excision is achieved relative to the distance of movement of the treatment tool by preventing a deflection of the flexible tube when in use. | 2008-12-11 |
20080306335 | Endoscopic vessel harvesting system components - Components for an endoscopic vessel harvesting system suitable for harvesting target vessels such as the saphenous vein or radial artery for cardiac artery bypass graft surgery. The main components of such systems include a vessel dissector and a vessel harvester, both of which work in conjunction with a separately provided endoscope. The vessel dissector is an elongated cannula having a blunt tip for separating layers of facial around vessels. The tip may be movable, and is typically transparent to permit viewing forward of the tip using the endoscope. Internal features of the tip may reduce glare back to the endoscope. Several devices improve visibility through the tip by reducing interference from tissue or fluid on the tip. The vessel harvester also has an elongated cannula for receiving the endoscope. Several tools within the harvester permit manipulation, severing, and sealing of vessels forward of the distal end. The tool for manipulating vessels may have a low-profile for increased visibility of operation, and may be coupled to the cannula with a damping mechanism to reduce the possibility of avulsion of the vessels. Various vessel cutting and sealing devices are provided that may accommodate various sizes of vessels and improve cutting and sealing efficacy. | 2008-12-11 |
20080306336 | RETRIEVAL DEVICE - An endoscopic device for retrieving an object from within a human body is disclosed. The device includes a support assembly, a transmitting assembly, a wire, and a net element. The support assembly has a base and a tubular member. The transmitting assembly includes a handle and a motion transmitting link fixed to the handle and extending through at least a portion of the tubular member. The wire defines a loop portion and two leg portions. A proximal end of each leg portion is secured to the link by a first connection and the two leg portions are secured to each other by at least a second connection distal from the first connection. The net element has a distal portion secured to the loop portion and a proximal portion secured relative to the leg portions. The loop portion is movable between an expanded position and a collapsed position. | 2008-12-11 |
20080306337 | Characterization of a Near-Infrared Laparoscopic Hyperspectral Imaging System for Minimally Invasive Surgery - The present invention includes an apparatus and methods for use of a hyperspectral surgical laparoscope that includes an illuminated laparoscope; a liquid crystal tunable filter generally center-mounted on the laparoscope and positioned to collect back-reflected light from a target; a relay lens generally center-mounted on the laparoscope to focus light from the liquid crystal tunable filter; and a focal plane array generally center-mounted on the laparoscope, wherein light that is reflected from the target is imaged on the focal plane array and captured as a digital data cube. | 2008-12-11 |
20080306338 | LIVING BODY OBSERVATION APPARATUS - A white light from a lamp passes through R, G, and B filters of a rotating filter and turns into broadband R, G, and B frame sequential illumination lights. The lights are applied to a living mucous membrane in a body cavity through an electronic endoscope, and sequential image pickup is performed by a CCD. Output signals from the CCD are sequentially switched by a selector in a filter circuit. An R signal, a G signal, and a B signal pass through the filter circuit | 2008-12-11 |
20080306339 | ROTATIONAL FORCE TRANSMISSION MECHANISM, FORCE-ATTENUATING APPARATUS, MEDICAL DEVICE, AND MEDICAL INSTRUMENT-OPERATION MECHANISM - A rotational force transmission mechanism has: a rotation-inputting member freely rotative and driven in a predetermined first direction and a second direction opposite the first direction by a predetermined operating member; a first rotation-transmitting member for receiving a rotational driving force supplied from the rotation-inputting member in the first direction; a second rotation-transmitting member, disposed to face the first rotation-transmitting member, for receiving a rotational driving force supplied from the rotation-inputting member in the second direction; a connection section disposed so that the rotational force acts in the direction in which the first rotation-transmitting member and the second rotation-transmitting member face each other, the connection section in the facing position transfers the rotational driving force received by the first rotation-transmitting member in the first direction to the second rotation-transmitting member and transfers the rotational driving force received by the second rotation-transmitting member in the second direction to the first rotation-transmitting member; and a rotation-outputting member rotated and driven by the first rotation-transmitting member in the second direction, and rotated and driven by the second rotation-transmitting member in the first direction. | 2008-12-11 |
20080306340 | ENCAPSULATED MEDICAL DEVICE GUIDANCE SYSTEM, AND METHOD OF CONTROLLING THE SAME - An encapsulated medical device guidance system, and a method of controlling the system, in which guidance coils are arranged to divide a magnetic field generating plane into at least two front and rear areas, a magnetic field for canceling gravity applied to a capsule endoscope itself is formed, and superposed on a magnetic field for moving or changing an attitude, a frictional resistance in moving a capsule endoscope is reduced by decreasing an area of an endoscope to contact the surface of an intracavital. | 2008-12-11 |
20080306341 | CAPSULE-TYPE ENDOSCOPE SYSTEM, AND PROGRAM AND METHOD USED FOR THE SYSTEM - A capsule-type endoscope system includes plural receivers, plural mounting spots for mounting the receivers and an information processing apparatus connected to the receivers via the mounting spots. Each receiver wirelessly receives image data from a capsule-type endoscope that images inside of an examinee's body; stores examinee identification information and the received image data; and displays the examinee identification information or examinee information associated therewith. The information processing apparatus receives the examinee identification information from each receiver via the mounting spot and manages its correlation with receiver identification information or mounting spot identification information. The image data is transmitted via the mounting spot to the information processing apparatus to be stored therein. The information processing apparatus displays the correlation by displaying at least a part of the examinee identification information or examinee information, and displays the progress of the transmission of image data corresponding to each receiver. | 2008-12-11 |
20080306342 | Surgical device - An in-line laparoscopic surgical instrument is provided, including a ratchet mechanism. The ratchet mechanism includes a single actuating means that may be used to engage, release, or defeat a ratchet engagement between portions of the handle. | 2008-12-11 |
20080306343 | ENDOSCOPIC DEVICE - An endoscopic device of the present invention comprises: an endoscope having an image pickup unit that outputs a picked up an image of a subject as an image pickup signal; an image pickup signal amplification unit; a light source unit; a light intensity control unit that controls an amount of light; a spectral unit that penetrates light in a band based on predetermined characteristics; a brightness control unit that controls a brightness of an image displayed on a display unit; and a mode switching unit that switches a first mode for emitting first illumination light and a second mode for emitting second illumination light having a band narrower than the first illumination light, wherein the brightness control unit controls the light intensity control unit and then controls the image pickup signal amplification unit in the second mode. | 2008-12-11 |
20080306344 | Surgical retractor securing device with capture assembly - A resilient compressive surgical retractor securing device with capture assembly includes a compressive securing device that compressively joins the resilient compressive surgical retractor securing device with capture assembly to a surgical accessory bar of a halo style head fixation device and a capture assembly that releasably retains the elasticized band of a scalp hook retractor. The compressive securing device is formed with an arm that is configured to form a neck for receiving the surgical accessory bar or other external support between the arm and the compressive securing device. The arm may be resilient or non-resilient, and may employ releasable closures to close the neck. The capture assembly may include a pivotable cam that releasably retains the elasticized band of a scalp hook retractor by compressing the band between the cam and the surgical accessory bar or other external support. | 2008-12-11 |
20080306345 | Vaginal Speculum Arrangement - A vaginal speculum arrangement includes a blade system for opening the vagina having a first blade ( | 2008-12-11 |
20080306346 | Diagnostic tool detecting the degradation status of Von Willebrand Factor multimers - A method in which the cleavage profile and size distribution of von Willebrand factor (VWF) multimers is analyzed, includes: providing a sample medium of human body fluids comprising a plurality of VWF multimers of different size; enrichment or purification of the VWF multimers by cryoprecipitation or chromatography to obtain a separated preparation of the VWF multimers from said sample medium; exposing the separated preparation of VWF multimers to a light source to produce signals obtained by vibrational spectroscopy; detecting said signals; transformation by mathematical alogrithms; generation of patterns based on computing of data of original resonance spectra and determining the cleavage profile and the size distribution of said separated VWF multimers by chemometrics; and acquisition of a databank obtained from healthy individuals for identifying subjects at risk of developing at least one of the following diseases: sepsis, coagulopathy, thrombotic disease, infection, and inflammation. | 2008-12-11 |
20080306347 | System and Method for a Telephone Feedback System for Fitness Programs - A diet management system and method thereof is disclosed, which aids in the facilitation of a diet and fitness feedback and tracking. In particular, a communication module, text-to-speech converter, VOX, and server are used in the diet management system. Several communication devices are employed that allows the dieter a broad choice of communicating dietary information. Moreover, the processing and storing of dietary reports are maintained by a network server. | 2008-12-11 |
20080306348 | MINIATURE WIRELESS APPARATUS FOR RECORDING PHYSIOLOGICAL SIGNALS OF HUMANS AND USE THEREOF - A miniature wireless apparatus for recording and remote monitoring physiological signals and use thereof are described. The miniature wireless apparatus comprises a signal collecting module, a signal processing module, a wireless module, and a recording device. The methods for recording and remote monitoring physiological signals comprising collecting physiological signals by a signal collecting module, processing the said physiological signals by a signal processing module and recording the processed signals by a recording device, modulating the said processed signals and synchronously transmitting and receiving the modulated signals by a wireless module to integrate the physiological signals, receiving the signals by a remote receiver, and recording, monitoring, and analyzing the physiological signals by the remote receiver and further transmitting the physiological signals to the remote monitoring station through a network. Methods for sleep monitoring and evaluating and for monitoring and evaluating of autonomic nerve function using the miniature wireless apparatus are further described. | 2008-12-11 |
20080306349 | Visual Working Memory Assessment Using Abstract Symbols and Associated Methods - A neuropsychological assessment of visual working memory includes a first display having a first set of distinct abstract elements positioned in a first order. A second display includes a second set of distinct abstract symbols positioned in a second order. The second set includes all the abstract elements of the first set plus at least one additional distinct abstract element not present in the first set. The first display is shown to an examinee. The examinee is asked to view the first display and to note the abstract elements in the first set and the first order thereof. The examinee is instructed to view the second display and to indicate, with reference to the second set, a location of each of the abstract elements present in the first set, in the first order. | 2008-12-11 |
20080306350 | Methods for Implementing a Weight Loss Program - A method for implementing a weight loss program is provided. The diet meal provider educates a health care professional about a diet meal plan or a dietary aid. The health care professional may recommend the plan to his or her patient who need to loose weight. Based on such recommendation, the patient will subscribe to receive the diet meal plan or the dietary which are supplied to the patient by the diet meal provider. | 2008-12-11 |
20080306351 | SLEEP EVALUATION DEVICE - A sleep evaluation device | 2008-12-11 |
20080306352 | Apparatus and System for Predictive Health Monitoring - An apparatus and system are provided for monitoring an individual, a group or a community of individuals for respiratory infections. Predictive health data, such as waking peak expiratory flow rate (“WPF”) and basal metabolic temperature (“BMT”) are measured and charted to provide an indication of early stage respiratory infection. Data may be collected for target populations and reported to health agencies for use in combating the spread of infection. An apparatus is provided which can simultaneously measure WPF and BMT and other health-condition-related values and automatically transmit readings to a data collection and analysis program on a remote computer. | 2008-12-11 |
20080306353 | CALCULATION DEVICE FOR METABOLIC CONTROL OF CRITICALLY ILL AND/OR DIABETIC PATIENTS - A method of providing blood glucose therapy for a critically ill patient includes calculating a baseline nutrition feed requirement based on an algorithm that incorporates at least one of age, gender, and body size of the patient: determining a first blood glucose level; determining a second blood glucose level after a preselected time interval: determining a first body temperature reading: comparing the blood glucose levels: and administering either nutrition or insulin. The amount of nutrition administered to the patient is based on a first change in blood glucose level, the current body temperature reading, and a predetermined feed algorithm based on the second blood glucose level as well as the baseline nutritional feed requirement. The amount of insulin administered is based on a second change in blood glucose level, body temperature, and a predetermined insulin algorithm that incorporates at least one of the patient's body frame size, age, and gender. | 2008-12-11 |
20080306354 | Enhanced Functionality and Accuracy For a Wrist-Based Multi-Parameter Monitor - A method for adjusting a blood pressure measurement to compensate for a pressure offset due to obtaining the blood pressure measurement at an elevation other than heart level is illustrated. The method includes measuring a blood pressure at a location above or below a heart level and adjusting the measured blood pressure in accordance with a pressure difference between the location at which the blood pressure is obtained and the heart level. | 2008-12-11 |
20080306355 | Method and System for Monitoring Gastrointestinal Function and Physiological Characteristics - A system and method for evaluating gastrointestinal motility and, optionally, other physiological characteristics (e.g., pulse rate) that can be effectively employed to acquire one or more signals associated with acoustic energy (i.e. sound) emanating from an abdominal region of a body and determine at least one gastrointestinal parameter or event based on the acoustic energy signal(s) is described. The gastrointestinal parameter can include a gastrointestinal event, including gastrointestinal mixing, emptying, contraction and propulsion, and gastrointestinal transit time, or a gastrointestinal system disorder, including reflux disease, irritable bowel disease, ulcerative colitis, constipation, diarrhea, and a migrating motor complex disorder. | 2008-12-11 |