49th week of 2011 patent applcation highlights part 48 |
Patent application number | Title | Published |
20110301282 | BLACK COLORED MASTER BATCH CARBON NANOTUBE AND METHOD OF MANUFACTURE THEREOF - A black plastic formed from between about 0.01% and 0.3% carbon nanotube material by weight. | 2011-12-08 |
20110301283 | FIBER REINFORCED POLYESTER COMPOSITION - The present invention relates to a process for the production of a solid state post condensated fiber reinforced polymer composition, preferably suitable for a brake booster, comprising the steps of: i) compounding a polymer composition comprising: (A) polyethylene terephthalate (PET) and/or polybutylene terephthalate (PBT) with a Mz/Mw<6.0, relative solution viscosity (RSV) of PET of less than 1.70 (determined by diluting 1 gram of polymer in 125 grams of solvent at 25° C., the solvent consisting of 7.2 parts by weight 2,4,6 trichlorophenol and 10 parts by weight phenol), and relative viscosity for PBT of less than 1.90, (determined by diluting 1 gram of PBT in 100 gr metacresol at 25° C.). (B) reinforcing fibers; and ii) heating the compounded polymer composition obtained in step i) under solid phase condensation conditions, thereby increasing the RSV of the PET to at least 1.70 and the RSV of the PBT to at least 1.90, while maintaining the ratio of z-average molecular mass to weight average molecular mass (Mz/Mw) of the solid state post PET and/or PBT substantially the same as the PET and/or PBT used for step i). | 2011-12-08 |
20110301284 | METHOD FOR MAKING CEMENTED CARBIDE PRODUCTS - A method for injection moulding or extrusion of cemented carbide or cermet parts with a solids loading of φ=0.54-0.56, using a binder system, includes 30-60 wt-% olefinic polymers, 40-70 wt-% waxes. The binder system further contains 2.5-10 wt-% petroleum jelly. A binder system for injection moulding or extrusion of cemented carbide or cermet parts, including 30-60 wt-% olefinic polymers, 40-70 wt-% waxes and further containing 2.5-10 wt-% petroleum jelly is also disclosed. | 2011-12-08 |
20110301285 | TWO-STAGE CURE POLYIMIDE OLIGOMERS - A method for using citraconic anhydride and itaconic anhydride as addition cure end caps in reactions for forming polyamic acid oligomers and polyimide oligomers, is provided. Prepregs and high temperature adhesives made from the resulting oligomers, as well as, high temperature, low void volume composites made from the prepregs, are also provided. | 2011-12-08 |
20110301286 | ADDITIVE, AN ADDITIVE RESIN REACTION PRODUCT, A METHOD OF TREATING A WOOD PRODUCT, AND A WOOD PRODUCT - An additive comprising a phosphazene compound that has at least two reactive functional groups and at least one capping functional group bonded to phosphorus atoms of the phosphazene compound. One of the at least two reactive functional groups is configured to react with cellulose and the other of the at least two reactive functional groups is configured to react with a resin, such as an amine resin or a polycarboxylic acid resin. The at least one capping functional group is selected from the group consisting of a short chain ether group, an alkoxy group, and an aryloxy group. Also disclosed are an additive-resin admixture, a method of treating a wood product, and a wood product. | 2011-12-08 |
20110301287 | RECYCLED COMPOSITE MATERIALS AND RELATED METHODS - Methods of producing particles of fiber and resin from fiber-resin composite materials are disclosed. The particles may be combined with a resin system and optionally combined with fillers, binders or reinforcements to produce new cured solid composite products. | 2011-12-08 |
20110301288 | THIOIC ACIDS AS BUILDING BLOCK FOR POLYTHIOESTERS - The present invention relates to thioic acids according to formula (II) suitable as building block for polythioesters; Wherein X is O, N or S and whereby R1 is chosen from (—CH | 2011-12-08 |
20110301289 | STABILIZED DRIER FOR ALKYD-BASED COMPOSITIONS - The present invention relates to a stabilized drying catalyst (‘drier’) for enhancing or accelerating oxidative air-drying of an alkyd-based composition, comprising an inclusion complex of a cyclodextrin and a metal salt of formula (M | 2011-12-08 |
20110301290 | METHOD FOR PRODUCING POLYAMIDE RESIN - A method for producing a polyamide resin characterized by comprising thermally polycondension of tetramethylene diamine and either an aliphatic dicarboxylic acid having 7 or more carbon atoms or a salt thereof, and then being melt-polymerized at a temperature equal to or higher than the melting point thereof until the relative viscosity of a 0.01 g/ml solution thereof in 98% sulfuric acid solution with a 0.01 g/ml content at 25° C. becomes 2.2-5.0. | 2011-12-08 |
20110301291 | OXAZOLINE AND/OR OXAZINE COMPOSITIONS - A curable composition comprising an oxazoline and/or an oxazine and a cationic cure initiator, in the absence of any phenolic compounds, is suitable for use as a molding or coating composition for semiconductor boards and devices. | 2011-12-08 |
20110301292 | BIO-BASED ROOFING ADHESIVE COMPOSITIONS - An adhesive composition for use in adhering insulation panels to roofing substrates and roofing membranes to the insulation panels include two components that are mixed prior to application on the roofing substrate. The first component may include a renewable polyol and catalyst. The renewable polyol is selected from any non-petroleum based polyol that is derived from a renewable source. The second component includes isocyanate, and may also include a polyol and a catalyst. The isocyanate and the polyol may each be any non-petroleum based isocyanate or polyol that is derived from a renewable source. | 2011-12-08 |
20110301293 | SILICON COMPOSITION AND ORGANIC LIGHT EMITTING DEVICE INCLUDING THE SAME - A silicon composition with a silicon compound represented by Formula 1 and a silicon compound represented by Formula 2: | 2011-12-08 |
20110301294 | PROCESS FOR PURIFYING POLYOL DISPERSIONS - The present invention relates to a process for purifying a polyol dispersion by stripping by means of at least one rotating body, to the polyol dispersion obtainable by the process according to the invention, and to the use thereof for preparing polyurethanes. | 2011-12-08 |
20110301295 | NOVEL COPOLYMERS WITH POLAR AND NON-POLAR OLEFIN BLOCKS - The present invention relates to copolymers with polar and non-polar olefin blocks with a variable polar monomer content of 0.1 mol % to 99.9 mol %. The invention also relates to a method for obtaining copolymers with olefin blocks and vinyl polar monomer blocks, said method using a single-component catalytic system made up of an organometallic complex containing a metal belonging to groups VIII to X. Said organometallic complex is advantageously active in the medium without adding cocatalyst. | 2011-12-08 |
20110301296 | PROCESS FOR PRODUCING PROPYLENE BLOCK COPOLYMER - A propylene block copolymer comprising 60 to 85% by weight of a propylene polymer component and 15 to 40% by weight of an ethylene-propylene copolymer component, and satisfying the following requirements (I) to (V): (I) the above propylene polymer component has a melting temperature of 160° C. or higher measured according to DSC; (II) the above ethylene-propylene copolymer component has an ethylene content of 40 to 60% by weight measured according to a | 2011-12-08 |
20110301297 | Thermally Switchable Ruthenium Initiators - This invention relates to ruthenium initiators for the ring-opening metathesis polymerization (ROMP) of cyclic olefins that are inactive at room temperature but activatable at elevated temperature (referred to as (“thermally switchable”). In general, these are compounds of ruthenium metal to which are bonded four or five ligands, in which one ligand is a pyridine ring in which the nitrogen is chelated to the ruthenium, or a five or six membered ring incorporating nitrogen and the ruthenium in which the nitrogen is chelated to the ruthenium. | 2011-12-08 |
20110301298 | ACID FUNCTIONALIZED GRADIENT BLOCK COPOLYMERS - The present invention relates to a class of acid functionalized gradient block copolymers, processes for obtaining them and to their uses including but not limited to hair fixatives, toughening agents, and adhesives. Surprisingly, the applicants have discovered the aforementioned class of acid functionalized gradient block copolymers have advantageous properties and can find utility in a wide variety of application areas. These polymers are easily prepared by sequential monomer addition (i.e., “one-pot” synthesis) and the process does not require any post polymerization modification steps. The aforementioned polymers are derived from commonly utilized monomers. The use of common monomers provides both an economic advantage and an inherent safety advantage, e.g., the common monomers are considered biocompatible. | 2011-12-08 |
20110301299 | Medical Devices and Polymers Therefor Having PTFE Surfaces Modified With Nitric Oxide-Releasing Polymers - Described herein are polymers useful for forming or coating implantable medical devices and such medical devices. The polymers are biocompatible and hemocompatible and comprise PTFE surfaces modified by covalently linking a nitric oxide releasing polymer to the PTFE surface through a linking group. Further described are precursor polymers and processes for preparing such polymers and precursor polymers. | 2011-12-08 |
20110301300 | NITRILE GROUP-CONTAINING HIGHLY SATURATED COPOLYMER RUBBER - A nitrile-group-containing highly saturated copolymer rubber comprising α,β-ethylenically unsaturated nitrile monomer units (a) in 5 to 60 wt %, α,β-ethylenically unsaturated dicarboxylic acid mono ester monomer units (b) in 0.1 to 20 wt %, (meth)acrylic acid alkoxyalkyl ester monomer units which have alkoxyalkyl groups with 2 to 8 carbon atoms (c) in 11 to 50 wt %, and conjugated diene monomer units (d) in 20 to 83.9 wt %, where at least part of the conjugated diene monomer units (d) are hydrogenated. | 2011-12-08 |
20110301301 | IMIDIZED POLYMERS CONTAINING LUMINESCENT GROUPS AND METHOD FOR OBTAINING THEM - The present invention relates to photoactive polymers and copolymers of acrylic monomers comprising cycloimide units functionalised with at least one luminescent chromophore group, preferably photoluminescent. The present invention also relates to spectrum converters comprising the above photoactive polymers and copolymers and solar devices comprising said converters. | 2011-12-08 |
20110301302 | METHOD OF MICROBIAL AND/OR ENZYMATIC DEVULCANIZATION OF RUBBER - A method for microbial and/or enzymatic devulcanization of rubber includes: providing a particulate vulcanized rubber compound, swelling the vulcanized rubber compound in a solvent, and introducing a microbe or enzyme into the solvent containing the particulate vulcanized rubber in order to devulcanize the rubber compound. | 2011-12-08 |
20110301303 | PROCESS FOR PREPARING WATER ABSORBENT RESIN WITH HIGH PERFORMANCE - The present invention relates to a process for preparing a water absorbent resin, particularly to a process for preparing a water absorbent resin which can resolve the uneven size of the fine pulverized gel-type resin and long pulverizing time those are the problems of prior process for preparing the water absorbent resin, by carrying out the pulverizing process of the gel-type resin divided into the coarse pulverizing process which is carried out with the internal cross-linking polymerization, and the fine pulverizing process. According to the preparation process, it is possible to mass-produce the water absorbent resin showing excellent absorption under pressure and low extractable content. | 2011-12-08 |
20110301304 | Method and apparatus for producing polycondensation polymer and molded article thereof - A method for producing a polycondensation polymer, which comprises: introducing a prepolymer of a polycondensation polymer into a polymerization reactor through a feed opening in a molten state; discharging the introduced prepolymer through holes of a perforated plate; and then polycondensing the prepolymer under reduced pressure, while allowing the prepolymer to fall along a support, wherein the perforated plate has two or more areas and polycondensation is performed by introducing a prepolymer and/or a polymer modifier into each of the areas and discharging the introduced prepolymer and/or polymer modifier through holes of each of the areas. | 2011-12-08 |
20110301305 | Fluorinated Dicarboxylic Acid Derivative and Polymer Obtained Therefrom - According to the present invention, a polymer is obtained by polycondensation of a fluorinated dicarboxylic acid derivative of the general formula (M-1) or an acid anhydride of the fluorinated dicarboxylic acid with a polyfunctional compound having two to four reactive groups corresponding in reactivity to carbonyl moieties of the fluorinated dicarboxylic acid derivative or acid anhydride. | 2011-12-08 |
20110301306 | POLYMERS MADE FROM POLYHEDRAL OLIGOMERIC SILSESQUIOXANES AND DIACETYLENE-CONTAINING COMPOUNDS - A compound having the formula below. Each R is methyl or phenyl; R | 2011-12-08 |
20110301307 | Ethylene Polymerization in a High Pressure Reactor with Improved Initiator Feeding - Process for the preparation of ethylene homopolymers or copolymers in a high pressure reactor with at least two spatially separated initiator injection points by polymerizing ethylene and optionally further monomers in the presence of at least two different mixtures of free-radical polymerization initiators at from 100° C. to 350° C. and pressures in the range of from 160 MPa to 350 MPa, wherein the process comprises the following steps:
| 2011-12-08 |
20110301308 | Increased run length in gas phase reactors - The time between shut downs of a gas phase reactor for the polymerization of polyethylene may be significantly increased if the catalyst used is not prepared by impregnating the support with a solution of catalyst in an electron donor; the reaction is controlled using the addition of activator based on polymer production rate and the recycle stream contains a condensed liquid phase in an amount greater than 13 weight %. Operating the reactor in this manner increase the time between cleaning the cooler (heat exchanger) the bed plate, or both from about 4 to 6 months to not less than about 24 months. | 2011-12-08 |
20110301309 | PROPYLENE HOMOPOLYMER FOR CAPACITORS - [Object] To provide a propylene homopolymer suitable for capacitor films having high withstand voltage and a stretched film formed by stretching the propylene homopolymer. | 2011-12-08 |
20110301310 | Pyridyldiamido Transition Metal Complexes, Production And Use Thereof - Pyridyldiamido transition metal complexes are disclosed for use in alkene polymerization. | 2011-12-08 |
20110301311 | SILICA-SUPPORTED OLIGOMERIC HYBRID MATERIALS - A particle-polymer hybrid material can include: a substance having the structure of Formula 1 (Z—(Y—FP) | 2011-12-08 |
20110301312 | CATIONIC POLYMER THICKENERS - Cationic polymer thickener consisting of a crosslinked water swellable cationic polymer containing at least one cationic monomer and optionally non-ionic and or anionic monomers wherein said polymer comprises less than 25% of water soluble polymeric chain by total weight of the polymer, and a cross-linking agent concentration of from 500 ppm to 5000 ppm relative to the polymer. | 2011-12-08 |
20110301313 | IMPRINT PRODUCT AND METHOD FOR PRODUCING THE SAME - Provided is an imprint product, which is for transcribing a fine pattern of a mold surface and which contains a fluorine-containing cyclic olefin polymer containing repeating unit represented by formula (1) and having a fluorine atom content rate of 40% to 75% by mass. | 2011-12-08 |
20110301314 | CONTINUOUS LIQUID-PHASE PROCESS FOR THE SYNTHESIS OF DIAMINOPYRIDINES FROM GLUTARONITRILES - A liquid-phase, continuous process is provided for the manufacture of 2,6-diaminopyridine and related compounds from glutaronitriles, which are used industrially as compounds and as components in the synthesis of a variety of useful materials. The synthesis proceeds by means of a dehydrogenative aromatization process. | 2011-12-08 |
20110301315 | FILM-FORMING METHOD BASED ON LB METHOD - Provided is a film-forming method based on an LB method by which a uniform alignment film using a helical polyacetylene can be obtained. The method based on the LB method includes: developing a helical polyacetylene onto a liquid surface; and transferring a monolayer film of the helical polyacetylene formed on the liquid surface onto a substrate to form a film, in which a compressibility P represented by the following formula (1) at a time of the film formation is 1×10 | 2011-12-08 |
20110301316 | METHOD FOR MANUFACTURING BIOMASS-DERIVED METHYL METHACRYLATE - Process for the manufacture of methyl methacrylate by oxidation of methacrolein to methacrylic acid and esterification of the latter with methanol, characterized in that at least one fraction of at least one from among methacrolein and methanol in this reaction was obtained by a reaction or a sequence of reactions starting from biomass. | 2011-12-08 |
20110301317 | NOVEL POLYUREASULFONE POLYMER - A polyureasulfone polymer having a high cohesive energy density and tensile strength, and method of making. | 2011-12-08 |
20110301318 | Mixed Polycycloaliphatic Amines (MPCA) And MPCA Alkylates - Mixed polycycloaliphatic amines (MPCA) and alkylates thereof (MPCA alkylates), methods for making mixed polycycloaliphatic MPCA amines and MPCA alkylates thereof, as well as polymeric compositions, such as spray-applied polyurea coating compositions, comprising said mixed amines MPCA and MPCA alkylates thereof are described herein. In one embodiment, the polymeric composition comprises an isocyanate component, and a resin component comprising an organic compound having the following Formula I: | 2011-12-08 |
20110301319 | METHOD OF PURIFYING A POLYMER - A method for purifying a polymer comprising providing a first mixture comprising at least one solvent and at least one polymeric material, diluting the first mixture with veratrole to produce a second mixture in which the polymeric material is substantially dissolved at a temperature less than 100° C., performing at least one step selected from (i) contacting the second mixture with an aqueous wash solution, and (ii) filtering the second mixture. | 2011-12-08 |
20110301320 | METHOD OF PURIFYING A POLYMER - A method for purifying a polymer comprising providing a first mixture comprising at least one solvent and at least one polymeric material, diluting the first mixture with veratrole to produce a second mixture in which the polymeric material is substantially dissolved at a temperature less than 100° C., performing at least one step selected from (i) contacting the second mixture with an aqueous wash solution, and (ii) filtering the second mixture. | 2011-12-08 |
20110301321 | METHOD OF MAKING POLY(ARYLENE ETHER) COMPOSITIONS - A method of making a thermoplastic composition comprises melt extruding a poly(arylene ether) powder to form a first pelletized poly(arylene ether); and melt extruding the first pelletized poly(arylene ether) to form a second pelletized poly(arylene ether), wherein the second pelletized poly(arylene ether) has a level of butyraldehyde less than the first pelletized poly(arylene ether) and the second pelletized poly(arylene ether) has a level of trimethylanisole less than the first pelletized poly(arylene ether). | 2011-12-08 |
20110301322 | CATALYST FOR POLYESTER POLYCONDENSATION AND METHOD FOR PRODUCING POLYESTER RESIN USING THE SAME - The invention provides: a polycondensation catalyst for polyester production, which contains titanium atoms, alkaline earth metal atoms and phosphorus atoms, has high reactivity and excellent long-term storage stability, can be easily produced industrially, and has an advantage in cost; a polyester resin obtained with the catalyst; and a molded article. These are: a polymerization catalyst for polyester production containing titanium atoms, alkaline earth metal atoms and phosphorus atoms and having a specific constitution; a polyester resin obtained with the catalyst; and a molded article. | 2011-12-08 |
20110301323 | ALKOXYLATION PROCESSES AND CATALYSTS THEREFOR - A process of contacting an alkylene oxide with 2-methoxy-1-propanol (PM1) in the presence of an oligomeric Schiff base metal complex catalyst is disclosed. Further, a process involving contacting an alkylene oxide with an alkyl alcohol using an oligomeric Schiff base metal complex as a catalyst is also disclosed. Additionally, novel compositions which can be used as catalysts in processes involving the contacting of an alkyl alcohol with an alkylene oxide are also disclosed. | 2011-12-08 |
20110301324 | LIQUID CRYSTAL DISPLAY AND METHOD FOR MANUFACTURING SAME - A liquid crystal display is provided which is capable of reducing the occurrence of defective display due to variations in the initial alignment direction of a liquid crystal alignment control film in a liquid crystal display of an IPS scheme, realizing the stable liquid crystal alignment, providing excellent mass productivity, and having high image quality with a higher contrast ratio. The liquid crystal display has a liquid crystal layer disposed between a pair of substrates, at least one of the substrates being transparent, and an alignment control film formed between the liquid crystal layer and the substrate. At least one of the alignment control films | 2011-12-08 |
20110301325 | Preparation of PHA (Polyhydroxyalkanoates) From a Citric Residue - The present invention relates to an obtainment process of biodegradable polymers from a citric residue resulting from the processing of orange juice. The polymers obtained are polyesters classified as polyhydroxyalkanoates including, among them the poly(3-hydroxybutyrate) and poly(3-hydroxybutyrate-co-3-hydroxyvalerate). The biodegradable polymer is obtained from the batch culture process or fed batch culture process with or without recirculation of the cells, using as a carbon source the pre-treated pressing liquor and/or the citric molasses. The polyhydroxyalkanoates, herein described, can be used as substitutes of the synthetic polyesters in different areas, including the food, pharmaceutical, medical, agricultural and other areas. | 2011-12-08 |
20110301326 | SYSTEM AND METHOD FOR RECOVERING TURPENTINE DURING WOOD MATERIAL PROCESSING - A system, method and configuration for recovering turpentine during the manufacturing of wood chips, wood pellets or other substances that may include turpentine. In general, a turpentine recovery system is used to capture turpentine from exhaust of a dryer as wood chips are being dried. Advantageously, application of the various techniques disclosed herein can result in the recovery of turpentine that can then be sold to generate revenue and, may contribute to a reduction in the capital and operation costs for emission controls for the dryer exhaust. | 2011-12-08 |
20110301327 | EPITOPE ANALOGS - Some embodiments relate to analogs of peptides corresponding to class I MHC-restricted T cell epitopes and methods for their generation. These analogs can contain amino acid substitutions at residues that directly interact with MHC molecules, and can confer improved, modified or useful immunologic properties. Additionally classes of analogs, in which the various substitutions comprise the non-standard residues norleucine and/or norvaline, are disclosed. | 2011-12-08 |
20110301328 | POLYVALENT VACCINE - The present invention relates, in general, to an immunogenic composition (e.g., a vaccine) and, in particular, to a polyvalent immunogenic composition, such as a polyvalent HIV vaccine, and to methods of using same. The invention further relates to methods that use a genetic algorithm to create sets of polyvalent antigens suitable for use, for example, in vaccination strategies. | 2011-12-08 |
20110301329 | Process for the Purification of Recombinant Albumin - A process is provided for the preparation of a highly pure albumin solution the process comprising subjecting albumin (preferably expressed and secreted by transformed yeast) to a series of chromatographic steps. Preferably, the process comprises the steps of positive mode cation exchange chromatography, positive mode anion exchange chromatography, positive mode affinity chromatography, negative mode affinity chromatography (preferably using immobilised aminophenylboronic acid), negative mode cation exchange chromatography, and negative or positive mode anion exchange chromatography. A process for reducing the level of nickel in an albumin solution is also disclosed, as is a recombinant albumin coding sequence comprising two or more in-frame translation stop codons. Also disclosed is a process for producing recombinant albumin, the process comprising culturing a fungal cell expressing a is recombinant albumin coding sequence, wherein the cell has a reduced capacity of mannosylation of the recombinantly-expressed albumin. | 2011-12-08 |
20110301330 | CELLULOSE GEL FOR PURIFICATION OF IMMUNOGLOBULIN - The present invention provides a chromatography packing material having improved flow rate characteristics and adsorption characteristics. In particular, the present invention provides a chromatography packing material suitable for separation and purification of immunoglobulin in the manufacture of antibody preparations. A porous cellulose gel, which is made by adding polysaccharides having a limiting viscosity of 0.21 to 0.90 dL/g to porous cellulose particles, the dry weight per unit volume of the porous cellulose gel being 1.06 to 1.40 times the dry weight per unit volume of the porous cellulose particles, is used. By adding a predetermined amount of polysaccharides having a predetermined limiting viscosity to porous cellulose particles, flow rate characteristics and adsorption characteristics can be improved. | 2011-12-08 |
20110301331 | Stabilized polypeptide compositions - The invention is based, at least in part, on the development of stabilized binding molecules that consist of or comprise a stabilized scFv and methods for making such stabilized molecules. | 2011-12-08 |
20110301332 | ANTI-PAMP THERAPEUTIC ANTIBODIES - The invention relates to antibodies and antigen-binding fragments thereof which bind to proadrenomedullin N-terminal peptide (“PAMP”). Furthermore, the invention comprises monoclonal antibody EGX-P-E9 as well as engineered variants thereof, including chimeric, humanized or de-immunized versions thereof. The antibodies of the invention are useful for inhibiting the physiological activities of PAMP as well as in diagnosis of PAMP-responsive conditions. | 2011-12-08 |
20110301333 | REMOVAL OF PROTEIN AGGREGATES FROM BIOPHARMACEUTICAL PREPARATIONS USING CALCIUM PHOSPHATE SALTS - The present invention provides novel and improved compositions containing calcium phosphate and methods of using the same for the removal of protein aggregates from biopharmaceutical compositions containing a product of interest, e.g., a therapeutic antibody or protein. | 2011-12-08 |
20110301334 | CYSTEINE ENGINEERED ANTIBODIES AND CONJUGATES - Cysteine engineered antibodies comprising a free cysteine amino acid in the heavy chain or light chain are prepared by mutagenizing a nucleic acid sequence of a parent antibody and replacing one or more amino acid residues by cysteine to encode the cysteine engineered antibody; expressing the cysteine engineered antibody; and isolating the cysteine engineered antibody. Certain highly reactive cysteine engineered antibodies were identified by the PHESELECTOR assay. Isolated cysteine engineered antibodies may be covalently attached to a capture label, a detection label, a drug moiety, or a solid support. | 2011-12-08 |
20110301335 | ANTI-TNFR1 POLYPEPTIDES, ANTIBODY VARIABLE DOMAINS & ANTAGONISTS - The invention relates to anti-TNFR1 polypeptides, antibody single variable domains (dAbs), antagonists and multispecific ligands, as well as methods and uses of these. The anti-TNFR1 polypeptides, antibody single variable domains (dAbs), antagonists and multispecific ligands are useful for treating and/or preventing inflammatory disease, such as arthritis or COPD, as well as for pulmonary administration, oral administration, delivery to the lung and delivery to the GI tract of a patient. | 2011-12-08 |
20110301336 | ANTIBODY PRODUCED USING OSTRICH AND METHOD FOR PRODUCTION THEREOF - Disclosed is an antibody produced using an ostrich. Also disclosed is a method for producing the antibody. By using an ostrich, it becomes possible to produce antibodies (particularly antibodies for medical use), which have been hardly produced by using the mammals such as the mouse and the rat, homogeneously in a single body, in large quantities and in a simple manner. The method can overcome a disadvantage of lot-to-lot variation which may occur in the production of polyclonal antibodies using other animals. | 2011-12-08 |
20110301337 | NOVEL INHIBITORS OF VASCULAR ENDOTHELIAL GROWTH FACTOR ACTIVITY, THEIR USES AND PROCESSES FOR THEIR PRODUCTION - The present invention is directed to novel chimeric VEGF receptor proteins comprising amino acid sequences derived from the vascular endothelial growth factor (VEGF) receptors flt-1 and KDR, including the murine homologue to the human KDR receptor FLK-1, wherein said chimeric VEGF receptor proteins bind to VEGF and antagonize the endothelial cell proliferative and angiogenic activity thereof. The present invention is also directed to nucleic acids and expression vectors encoding these chimeric VEGF receptor proteins, host cells harboring such expression vectors, pharmaceutically acceptable compositions comprising such proteins, methods of preparing such proteins and to methods utilizing such proteins for the treatment of conditions associated with undesired vascularization. | 2011-12-08 |
20110301338 | NOVEL INHIBITORS OF VASCULAR ENDOTHELIAL GROWTH FACTOR ACTIVITY, THEIR USES AND PROCESSES FOR THEIR PRODUCTION - The present invention is directed to novel chimeric VEGF receptor proteins comprising amino acid sequences derived from the vascular endothelial growth factor (VEGF) receptors flt-1 and KDR, including the murine homologue to the human KDR receptor FLK-1, wherein said chimeric VEGF receptor proteins bind to VEGF and antagonize the endothelial cell proliferative and angiogenic activity thereof. The present invention is also directed to nucleic acids and expression vectors encoding these chimeric VEGF receptor proteins, host cells harboring such expression vectors, pharmaceutically acceptable compositions comprising such proteins, methods of preparing such proteins and to methods utilizing such proteins for the treatment of conditions associated with undesired vascularization. | 2011-12-08 |
20110301339 | NOVEL INHIBITORS OF VASCULAR ENDOTHELIAL GROWTH FACTOR ACTIVITY, THEIR USES AND PROCESSES FOR THEIR PRODUCTION - The present invention is directed to novel chimeric VEGF receptor proteins comprising amino acid sequences derived from the vascular endothelial growth factor (VEGF) receptors flt-1 and KDR, including the murine homologue to the human KDR receptor FLK-1, wherein said chimeric VEGF receptor proteins bind to VEGF and antagonize the endothelial cell proliferative and angiogenic activity thereof. The present invention is also directed to nucleic acids and expression vectors encoding these chimeric VEGF receptor proteins, host cells harboring such expression vectors, pharmaceutically acceptable compositions comprising such proteins, methods of preparing such proteins and to methods utilizing such proteins for the treatment of conditions associated with undesired vascularization. | 2011-12-08 |
20110301340 | Toxins and Radionuclides Coupled to IGF-1 Receptor Ligands for Treatment of Cancer - The invention provides an insulin-like growth factor-1 (IGF-1) receptor ligand carrying a therapeutic radionuclide for treatment of cancer is provided. A method of treating cancer using the IGF-1 receptor ligand carrying a therapeutic radionuclide is also provided. An anti-cancer therapeutic agent containing an IGF-1 receptor ligand linked to a toxin is also provided, as are methods of using the toxin conjugates for treatment of cancer. | 2011-12-08 |
20110301341 | MODIFIED ORGANS AND CELLS FOR XENOTRANSPLANTATION - It has been discovered that there are at least two significant antigens present on the cells of animal species such as pigs that elicit an immune or inflammatory response immediately upon implantation into humans or contact with human serum. The first is an α-galactosyl (Gal) epitope, for example, Galα(1->3)Galβ(1->4)GlcNac (linear B type 2) or Galα(1->3)Galβ(1->4)Glc (linear B type 6). The second is an N-glycolylneuraminic acid (NeuGc) structure. By eliminating these epitopes, preferably by genetically engineering the animal so that the epitope is either not produced or is greatly reduced. or by chemical or enzymatic treatment of the animal's cells to remove the epitopes, it is possible to produce organs, tissues and cells suitable for xenotransplantation into humans. Cells can be rendered even more compatible by genetically engineering the animal to express a human complement regulatory protein (inhibitor), such as CD59, on its cells, or to express an excess of a pig complement regulatory protein. | 2011-12-08 |
20110301342 | APPARATUS AND PROCESS FOR PURIFICATION OF PROTEINS - The invention is directed to an apparatus and method for purifying a protein. The apparatus involves the use of a capture chromatography resin, a depth filter arranged after the capture chromatography resin, and a mixed-mode chromatography resin arranged after the depth filter. The method involves providing a sample containing the protein, processing the sample through a capture chromatography resin, a depth filter, and a mixed-mode chromatography resin. A membrane adsorber or monolith may be substituted for the mixed-mode chromatography column. | 2011-12-08 |
20110301343 | METHODS AND COMPOSITIONS FOR DEPLETING ABUNDANT RNA TRANSCRIPTS - The present invention concerns a system for isolating, depleting, and/or preventing the amplification of a targeted nucleic acid, such as mRNA or rRNA, from a sample comprising targeted and nontargeted nucleic acids. | 2011-12-08 |
20110301344 | WATER-SOLUBLE PHTHALOCYANINE DYE - The invention has for its object to provide a water-soluble phthalocyanine dye unlikely to lose its own properties even upon dissolved in a concentration as high as 10 | 2011-12-08 |
20110301345 | METHOD FOR PRODUCING 1:1 ADDUCTS HAVING A LOW MONOMER CONTENT FROM HYDROXYALKYL(METH)ACRYLATES AND DIISOCYANATES - The present invention relates to the production and the use of 1:1 adducts having a low monomer content from hydroxyalkyl(meth)acrylates and diisocyanates. | 2011-12-08 |
20110301346 | PROCESS FOR THE PURIFICATION OF AMOROLFINE HYDROCHLORIDE - The present invention relates to a process for the purification of amorolfine hydrochloride by means of a reversed-phase preparative high performances liquid chromatography (prep-HPLC) said method starting from a crude Amorolfine hydrochloride having purity higher than 90% and containing Bepromoline hydrochloride <5% and Fenpropimorf <3%. The process involves the use of a mobile phase comprising water and an organic solvent under isocratic conditions. | 2011-12-08 |
20110301347 | BENZYL, AMINES, A PROCESS FOR THEIR PRODUCTION AND THEIR USE AS ANTI-INFLAMMATORY AGENTS - The present invention relates to the compounds of formula I, | 2011-12-08 |
20110301348 | Process for the Manufacture of the Calcium Salt of Rosuvastatin (E)-7-[4-(4-Fluorophenyl)-6-Isopropyl-2-[Methyl(Methylsulfonyl)Amino]-Pyr- imidin-5-yl](3R,5S)-3,5-Dihydroxyhept-6-Enoic Acid and Crystalline Intermediates Thereof - A process for the manufacture of the calcium salt of (E)-7-[4-(4-fluorophenyl)-6-isopropyl-2-[methyl(methylsulfonyl)amino]pyrimidin-5-yl](3R,5S)-3,5-dihydroxyhept-6-enoic acid, useful as an HMGCoA reductase inhibitor, from a compound of the formula (7) | 2011-12-08 |
20110301349 | METHODS OF PREPARING 4-PHENYL-6-(2,2,2-TRIFLUORO-1-PHENYLETHOXY)PYRIMIDINE-BASED COMPOUNDS - Methods useful for preparing compounds of formula I: | 2011-12-08 |
20110301350 | PROCESS FOR PREPARING CYCLOALKYL-SUBSTITUTED PIPERAZINE COMPOUNDS - The present invention relates to a process for preparing compounds of general formula I | 2011-12-08 |
20110301351 | Platinum (II) Di (2-Pyrazolyl) Benzene Chloride Analogs and Uses - Synthesis of platinum(II) di(2-pyrazolyl)benzene chloride and analogs includes forming a 1,3-di-substituted benzene including two aromatic five-membered heterocycles, and reacting the 1,3-di-substituted benzene with an acidic platinum-containing solution to form a luminescent platinum(II) complex. The luminescent platinum(II) complex is capable of emitting blue and white light and can be used as an emitter in a light emitting device. | 2011-12-08 |
20110301352 | PROCESS FOR THE PREPARATION OF CIS-2-METHYLSPIRO (1, 3-OXATHIOLANE 5-3') QUINUCLIDINE - Methods are provided for making pharmaceutical-grade cis-2-methylspiro(1,3-oxathiolane-5,3′)quinuclidine and pharmaceutically acceptable salts thereof by isomerizing racemic 2-methylspiro(1,3-oxathiolane-5,3′)quinuclidine to cis-2-methylspiro(1,3-oxathiolane-5,3′)quinuclidine and subsequent purification of the C-MSOQ by salt formation with inexpensive and commercially available material such as sulfuric acid. Purification methods are disclosed which employ an organic solvent/water system and recrystallization with an organic solvent such as acetone. | 2011-12-08 |
20110301353 | PYRROLO [3,2-C] PYRIDINE-4-ONE 2-INDOLINONE PROTEIN KINASE INHIBITORS - The present invention relates to pyrrolo[3,2-c]pyridine-4-one 2-indolinone compounds of Formula (I) and their pharmaceutically acceptable salts thereof, wherein R | 2011-12-08 |
20110301354 | EXPLOSIVE COMPLEXES - Lead-free primary explosives of the formula [M | 2011-12-08 |
20110301355 | Amidine compounds and herbicides - Novel amidine compounds which may be active ingredients in herbicides that are reliably effective at a lesser dose and highly safe, and herbicides containing these compounds as active ingredients are provided. Amidine compounds represented by a formula (1′) | 2011-12-08 |
20110301356 | Method for Producing 2-aminobiphenylene - The present invention relates to a process for preparing 2-aminobiphenyls of the formula I | 2011-12-08 |
20110301357 | NOVEL POLYMORPHIC FORMS OF PERINDOPRIL (L)-ARGININE AND PROCESS FOR THE PREPARATION THEREOF - The present invention relates to novel and stable polymorphic forms of Perindopril (L)-Arginine designated as Form γ and amorphous form and processes for their preparation. The present invention also provides the novel polymorph Form γ with greater stability to heat and humidity and can be prepared on large scale by an efficient, economic and reproducible process. | 2011-12-08 |
20110301358 | Novel Forms of [R-(R*,R*)]-2-(4-fluorophenyl)-beta,delta-Dihydroxy-5-(1-Methylethyl)-3-P- henyl-4-[(Phenylmino)Carbonyl]-1H-Pyrrole-1-Heptanoic Acid Calcium Salt (2:1) - Novel forms of [R—(R*,R*)]-2-(4-fluorophenyl)-β,δ-dihydroxy-5-(1-methylethyl)-3-phenyl-4-[(phenylamino)carbonyl]-1H-pyrrole-1-heptanoic acid hemi calcium salt designated Form XX, Form XXI, Form XXII, Form XXIII, Form XXIV, Form XXVV, Form XXVI, Form XXVII, Form XXVIII, Form XXIX, and Form XXX, characterized by their X-ray powder diffraction, solid-state NMR, and/or Raman spectroscopy are described, as well as methods for the preparation and pharmaceutical composition of the same, which are useful as agents for treating hyperlipidemia, hypercholesterolemia, osteoporosis, benign prostatic hyperplasia (BPII) and Alzheimer's disease. | 2011-12-08 |
20110301359 | PROCESS FOR THE PRODUCTION OF CYCLOPROPANE DERIVATIVES - A process for the preparation of a cyclopropane derivative of Formula (I), by reacting an olefin of Formula (II), with a carbene of the formula: CR | 2011-12-08 |
20110301360 | THIOPHENE COMPOUNDS FOR LIQUID-CRYSTALLINE MEDIA - The invention relates to liquid-crystalline compounds of the formula I | 2011-12-08 |
20110301361 | METHOD OF RETAINING THE QUALITY OF 2-METHYL-3-(3,4-METHYLENEDIOXYPHENYL) PROPANAL AND PROCESS FOR PRODUCING THE SAME - The present invention relates to [1] a method for keeping a quality of 2-methyl-3-(3,4-methylenedioxyphenyl)propanal useful as a perfume, which comprises incorporating from 50 to 3000 ppm of 1-acetyl-3,4-methylenedioxybenzene in the 2-methyl-3-(3,4-methylenedioxyphenyl)propanal; [2] a process for producing 2-methyl-3-(3,4-methylenedioxyphenyl)propanal having a content range from 50 to 3000 ppm of 1-acetyl-3,4-methylenedioxybenzene; and [3] 2-methyl-3-(3,4-methylenedioxyphenyl)propanal having a content range from 50 to 3000 ppm of 1-acetyl-3,4-methylenedioxybenzene. | 2011-12-08 |
20110301362 | NOVEL LIQUID TETRACARBOXYLIC DIANHYDRIDES AND PROCESS FOR THE PREPARATION THEREOF - The invention relates to a tetracarboxylic dianhydride represented by the following formula (1). | 2011-12-08 |
20110301363 | METHOD FOR CARRYING OUT OXIDATION REACTIONS USING INDUCTIVELY HEATED HEATING MEDIUM - The invention relates to a method for carrying out an oxidation reaction for producing a product by heating a reaction medium containing a reactant and oxygen or an oxygen carrier in a reactor, wherein the reaction medium is brought into contact with a solid heating medium which may be heated by electromagnetic induction, which is surrounded by the reaction medium. The heating medium is heated by electromagnetic induction using an inductor, wherein an oxidation reaction is carried out on the first reactant to give a product and the product is separated from the heating medium. The inductor preferably generates an alternating field with a frequency in the range 1 to 100 kHz, preferably in the range 10 to 80 kHz and in particular up to 50 kHz. | 2011-12-08 |
20110301364 | PROCESSES FOR THE PRODUCTION OF HYDROGENATED PRODUCTS - A process for making a hydrogenated product includes providing a clarified DAS-containing fermentation broth, distilling the broth to form an overhead that includes water and ammonia, and a liquid bottoms that includes MAS, at least some DAS, and at least about 20 wt % water, cooling and/or evaporating the bottoms, and optionally adding an antisolvent to the bottoms, to attain a temperature and composition sufficient to cause the bottoms to separate into a DAS-containing liquid portion and a MAS-containing solid portion that is substantially free of DAS, separating the solid portion from the liquid portion, recovering the solid portion, hydrogenating the second solid portion in the presence of at least one hydrogenation catalyst to produce the hydrogenated product comprising at least one of THF, GBL or BDO, and recovering the hydrogenated product. | 2011-12-08 |
20110301365 | ALPHA-SUBSTITUTED ALPHA, BETA-UNSATURATED E- OR Z-ALDEHYDES, USE THEREOF, AND PROCESSES FOR THEIR PREPARATION ALPHA, BETA - This invention relates to novel alpha-substituted α,β-unsaturated E- or Z-aldehydes, or isomer mixture thereof, of the formula | 2011-12-08 |
20110301366 | EPOXY RESIN PRODUCTION - A process comprising contacting a polyhydric phenol or a polyaliphatic alcohol with an epihalohydrin in the presence of a catalyst comprising a Schiff base metal complex is disclosed. | 2011-12-08 |
20110301367 | METHOD FOR PREPARING AN EPOXIDATION CATALYST - A process for the preparation of a catalyst useful for the vapor phase production of ethylene oxide from ethylene and oxygen comprising the steps of providing a catalyst precursor comprising an inert support having a catalytically effective amount of a silver containing compound, a promoting amount of an alkali metal containing compound, and a promoting amount of a transition metal containing compound disposed thereon; and heating the catalyst precursor in a gas atmosphere for a first period of time and a second period of time, wherein for the first period of time the gas atmosphere is an inert gas atmosphere and the temperature range is from about 25° C. to about 600° C., and then in a second period of time the gas atmosphere is an oxygen-containing atmosphere and the second period temperature range is from about 350° C. to about 600° C. | 2011-12-08 |
20110301368 | Carrier for Ethylene Oxide Catalysts - An improved carrier for an ethylene epoxidation catalyst is provided. The carrier includes an alumina component containing a first portion of alumina particles having a particle size of, or greater than, 3 μm and up to 6 μm, and a second portion of alumina particles having a particle size of, or less than, 2 μm. An improved catalyst containing the above-described carrier, as well as an improved process for the epoxidation of ethylene using the catalyst are also provided. | 2011-12-08 |
20110301369 | EXFOLIATED CLAY/SURFACTANT COMPLEX FOR INHIBITING MICROORGANISMS, VIRUSES OR PLANT PESTS - The present invention provides an exfoliated clay/surfactant complex for inhibiting microorganisms, viruses or plant pests. The weight ratio of the exfoliated clay to the surfactant can range from 99/1 to 1/99. Preferably, the exfoliated clay is an inorganic layered clay on a nano scale and the surfactant is cationic, nonionic, anionic or amphoteric. | 2011-12-08 |
20110301370 | METHOD FOR PREPARING OREGANIC ACID - The present invention is aimed at a process for obtaining oreganic acid and derivatives thereof, to the intermediate compounds of this synthesis and to the use of | 2011-12-08 |
20110301371 | PROCESS - A process for producing a conjugated di- or poly-unsaturated fatty acid having from 12 to 24 carbon atoms, or a salt or ester thereof, comprises: reacting a non-conjugated free fatty acid, or a salt or ester thereof, with a base in the presence of an alcoholic solvent comprising ethanol; and separating the conjugated fatty acid from the reaction mixture, wherein the separation of the conjugated fatty acid from the reaction mixture comprises contacting the reaction mixture with an aqueous salt solution and removing a liquid phase which comprises the salt solution and at least a part of the solvent from a solid phase which comprises a salt of the conjugated fatty acid. | 2011-12-08 |
20110301372 | DRY OIL-AND-FAT SEPARATION METHOD - Disclosed is a dry oil-and-fat separation method of high yield and high separation accuracy, which uses agitation and crystallization in order to prevent problems with thickening of the crystal slurry and decreased solid/liquid separation efficiency in the crystallization/press-filtering process of dry separation of oil-and-fat containing highly crystalline SUS. In dry separation, the crystallization/press-filtering process is divided into multiple steps and repeated, to concentrate the SUS in each crystal fraction and yield SUS-rich oil and fat. Subdivision into multiple steps makes it possible to keep the crystallinity of the crystal slurry in the crystallization/press-filtering process within a range so that the crystal slurry can be transported by pump, and to increase solid/liquid separation efficiency. | 2011-12-08 |
20110301373 | CYCLIC AZA-SILA COMPOUNDS - The invention relates to cyclic aza-sila compounds that are made of 4 to 10 units of the general formulas (I) and (II) bonded by means of Si—Si or Si—N single bonds, wherein Y is selected from among —NR | 2011-12-08 |
20110301374 | METHOD FOR PRODUCING ORGANOSILICON COMPOUNDS HAVING AMINO GROUPS - Amino group-containing organosilicon compounds containing no or only a small fraction of Si-bonded hydroxyl groups are prepared by preparing an organosilicon compound containing amino groups and Si-bonded hydroxyl groups by equilibration in the presence of an equilibration catalyst, and reacting the resultant product with a cyclic silazane. The products are particularly useful as a monomer or macromere for the preparation of high molecular weight organic polymers containing organosilicon blocks. | 2011-12-08 |
20110301375 | Organosilicon Compound And Method Of Producing Same - A hydrolyzable group-containing organosilicon compound is represented by the general formula | 2011-12-08 |
20110301376 | PREPARATION OF CRYSTALLINE EZATIOSTAT HYDROCHLORIDE ANSOLVATE FORM D - Provided herein are processes of preparing ezatiostat hydrochloride, and crystalline ezatiostat hydrochloride ansolvate form D. | 2011-12-08 |
20110301377 | PRODUCTION OF CARBOXYLIC ACID ESTERS BY STRIPPING WITH ALCOHOL VAPOR - The invention relates to a method for producing carboxylic acid esters by reacting a reaction mixture, comprising a carboxylic acid and/or a carboxylic acid anhydride, and an alcohol in a reaction system having one or more reactors, wherein reaction water is distilled off as an alcohol/water azeotrope with the exhaust vapor. In addition, the reaction mixture is treated with superheated alcohol vapor. The method allows the production of esters having a low acid number. | 2011-12-08 |
20110301378 | Process for the preparation of esters of 4-fluorosubstituted 3-oxo-alcanoic acids - Esters of 4-fluorosubstituted 3-oxo-alcanoic acids can be prepared by addition reaction of ketene with the respective acid chloride, subsequent esterification and hydrodechlorination. Preferred reaction products are esters of 4,4-difluoro-3-oxo-butanoic acid. | 2011-12-08 |
20110301379 | METHOD FOR PRODUCING A (METH)ACRYLATE - Disclosed is a method for producing a (meth)acrylate ester wherein a high purity (meth)acrylate ester is obtained with a high yield, with a reduced loss of (meth)acrylic acid anhydride. In the method, (meth)acrylic acid is recovered with a high yield, and the (meth)acrylate ester is purified easily. Specifically disclosed is a method for producing a (meth)acrylate ester which comprises: (1) a step of producing (meth)acrylic acid anhydride by reacting a specific fatty acid anhydride and (meth)acrylic acid, while removing a by-produced fatty acid; (2) a step of obtaining a (meth)acrylate ester by reacting an alcohol and unpurified (meth)acrylic acid anhydride obtained in step (1) preferably at a temperature not less than 90° C.; and (3) a step of recovering (meth)acrylic acid by distillation preferably at a temperature not less than 90° C. The method may also comprise a step of heating or distilling the reaction liquid obtained in step (2) at a temperature not less than 90° C. | 2011-12-08 |
20110301380 | PROCESS AND APPARATUS FOR PREPARING ISOCYANATES - The invention relates to a process for preparing isocyanates by reacting the corresponding amines with phosgene in the gas phase, optionally in the presence of an inert medium, in which the amine is evaporated in an evaporator to give an amine-comprising gas stream, the phosgene is mixed into the amine-comprising gas stream, and the amine and the phosgene are converted to the isocyanate in a reactor, wherein the temperature of surfaces in contact with the gaseous amine is kept above the dew point limit of the amine-comprising gas stream. The invention further relates to an apparatus for preparing isocyanates by reacting the corresponding amines with phosgene in the gas phase, comprising an evaporator to evaporate the amine and a reactor in which the reaction is effected, and means of connection of evaporator and reactor, wherein surfaces which can come into contact with gaseous amine are provided with a coating which is not wetted by amine or have an averaged roughness depth Rz to DIN ISO 4287 of not more than 10 μm, and/or the apparatus has no dead spaces or thermal bridges. | 2011-12-08 |
20110301381 | Transition Metal-Containing Catalysts and Processes for Their Preparation and Use As Oxidation and Dehydrogenation Catalysts - This invention relates to the field of heterogeneous catalysis, and more particularly to catalysts including carbon supports having formed thereon compositions which comprise a transition metal in combination with nitrogen and/or carbon. The invention further relates to the fields of catalytic oxidation and dehydrogenation reactions, including the preparation of secondary amines by the catalytic oxidation of tertiary amines and the preparation of carboxylic acids by the catalytic dehydrogenation of alcohols. | 2011-12-08 |