49th week of 2013 patent applcation highlights part 47 |
Patent application number | Title | Published |
20130323272 | NOVEL AND POWERFUL MHC-CLASS II PEPTIDES DERIVED FROM SURVIVIN - The present invention relates to peptides, nucleic acids, and cells for use in the immunotherapy of cancer. The present invention furthermore relates to survivin-derived tumor-associated cytotoxic T cell (CTL) peptide epitopes, alone or in combination with other tumor-associated peptides that serve as active pharmaceutical ingredients of vaccine compositions that stimulate anti-tumor immune responses. The present invention specifically relates to three novel peptide sequences and variants thereof derived from HLA class I and class II molecules of human tumor cells that can be used in vaccine compositions for eliciting anti-tumor immune responses. | 2013-12-05 |
20130323273 | Adipogenic Adenoviruses as a Biomarker for Disease - A vaccine composition may be administered to a subject to increase immunity to an adipogenic adenovirus-related cancer. The vaccine composition stimulates the production of adipogenic adenovirus neutralizing antibodies in the subject, which may increase immunity to the adipogenic adenovirus-related cancer in the subject. | 2013-12-05 |
20130323274 | ESCHERICHIA COLI IMMUNOGENS WITH IMPROVED SOLUBILITY - Variants of the pathogenic | 2013-12-05 |
20130323275 | METHODS AND COMPOSITIONS FOR INDUCING A T-CELL RESPONSE TO PLASMODIUM SPECIES - The present invention relates to methods of inducing a T-cell response against a | 2013-12-05 |
20130323276 | MALARIA VACCINES BASED ON PRE-ERYTHROCYTIC ANTIGENS FROM P. FALCIPARUM - The present invention relates to polypeptides or fragments thereof for use as malaria vaccines. It also relates to nucleic acid molecules coding for the polypeptides of the invention. It further relates to compositions comprising such polypeptides or fragments thereof or the nucleic acid molecules, in particular combinations of such polypeptides or fragments thereof, and the use of such compositions as malaria vaccines. | 2013-12-05 |
20130323277 | SCHMALLENBERG VIRUS (SBV) VACCINE, METHODS OF PRODUCTION, AND USES THEREOF - The present invention relates to the field of vaccines and medicaments for the prophylaxis and treatment of infectious diseases in ruminants. In particular, it relates to inactivated Schmallenberg virus (SBV) useful as vaccine or medicament for preventing or treating viremia, the transmission and clinical symptoms, in particular malformations in newborn ruminants such as cattle, sheep and goats, induced by SBV. | 2013-12-05 |
20130323278 | Chimeric Flavivirus Vaccines - A chimeric live, infectious, attenuated virus containing a yellow fever virus, in which the nucleotide sequence for a prM-E protein is either deleted, truncated, or mutated, so that functional prM-E protein is not expressed, and integrated into the genome of the yellow fever virus, a nucleotide sequence encoding a prM-E protein of a second, different flavivirus, so that the prM-E protein of the second flavivirus is expressed. | 2013-12-05 |
20130323279 | Human Endogenous Retrovirus Polypeptide Compositions and Methods of Use Thereof - The present invention provides isolated HERV polypeptides; and compositions, including immunogenic compositions, comprising a HERV polypeptide. The present invention provides immunogenic compositions comprising a nucleic acid comprising a nucleotide sequence encoding a HERV polypeptide. The immunogenic compositions are useful for stimulating a T cell immune response to a lentiviral peptide. The present invention further provides methods of stimulating an immune response in an individual to a retrovirus- or lentivirus-infected cell. The present invention further provides methods of treating cancers in which HERV polypeptides are expressed. Also provided are methods of treating disorders, involving decreasing an immune response to a HERV polypeptide. | 2013-12-05 |
20130323280 | METHODS FOR PREPARING VESICLES AND FORMULATIONS PRODUCED THEREFROM - The present disclosure provides methods for preparing vesicles. In one aspect, the methods involve providing a molten mixture of vesicle-forming lipids and adding the molten mixture of vesicle-forming lipids to an aqueous solution comprising an antigen such that antigen-containing vesicles are formed, wherein in the step of adding the molten mixture of vesicle forming lipids is at a temperature of less than 120° C. In another aspect, the methods involve providing a molten mixture of vesicle-forming lipids and adding an aqueous solution comprising an antigen to the molten mixture of vesicle-forming lipids such that antigen-containing vesicles are formed, wherein the resulting mixture is placed under temperature-controlled conditions of less than 60° C. In yet another aspect, the methods involve providing a solution of vesicle forming lipids and adding the solution of vesicle-forming lipids to an aqueous solution comprising an antigen by injection such that antigen-containing vesicles are formed. | 2013-12-05 |
20130323281 | ORDERED FLAGELLIN ARRAY AS AN IMMUNOSTIMULANT - Bacterial flagellin protein is modified to improve adjuvant activity. | 2013-12-05 |
20130323282 | COMPOSITIONS AND METHODS - The present invention provides a composition comprising hepatitis C virus (HCV) Envelope 2 (E2) glycoprotein, wherein the HCV E2 is substantially monomer depleted HCV E2. Also provide are methods of inducing an HCV immune response. | 2013-12-05 |
20130323283 | COMPOSITIONS AND METHODS FOR TREATING FOXP3+ TREG RELATED DISEASES - Methods for treating or preventing a Foxp3+ T regulatory cell (Treg) related disease in a subject in need thereof comprise administering to the subject an effective amount of a pharmaceutical composition comprising an inhibitor of a histone/protein acetyltransferase (HAT). Methods for identifying an agent useful for treating or preventing a Foxp3+ T regulatory cell (Treg) related disease comprise (a) contacting a candidate agent with a test sample comprising Foxp3+ T regulatory cells (Tregs), and (b) comparing a function of the Foxp3+ Tregs in the test sample with that in a control sample, wherein inhibition of the function of the Foxp3+ Tregs in the test sample when compared with the control sample indicates that the candidate agent is an agent useful for treating or preventing a Foxp3+ Treg related disease. | 2013-12-05 |
20130323284 | USE OF mTOR INHIBITORS TO TREAT BACTERIAL INFECTION - A method for treating a mammal having an infection with an organism that persists intracellularly in a mammalian cell by inducing an autophagy defect includes administering to the mammal an effective dose of a bioavailable agent that restores autophagy function, by inhibition of the mTOR pathway. | 2013-12-05 |
20130323285 | PEPTIDE ADJUVANTS - Adjuvant compositions comprising specific 5mer polypeptides in combination with antigen delivery systems and/or immunostimulatory molecules, such as immunostimulatory nucleic acid sequences, for enhancing the immune response of a coadministered antigen, are described. | 2013-12-05 |
20130323286 | SYNTHESIS OF R-N-METHYLNALTREXONE - This invention relates to stereoselective synthesis of R-MNTX and intermediates thereof, pharmaceutical preparations comprising R-MNTX or intermediates thereof and methods for their use. | 2013-12-05 |
20130323287 | MULTIPLE UNIT DOSAGE FORM HAVING A THERAPEUTIC AGENT IN COMBINATION WITH A NUTRITIONAL SUPPLEMENT - Compositions and methods for combination therapy are provided. The compositions comprise a multiple unit dosage form having both a therapeutic agent and a nutritional supplement. The combination therapy is useful for restoring a nutrient depletion associated with a particular disease state. Additionally, the combination therapy can prevent or attenuate the depletion of a nutrient caused, in whole or in part, by the co-administrated therapeutic drug. Methods of manufacturing the formulations are likewise described. | 2013-12-05 |
20130323288 | PHARMACEUTICAL FORMULATION FOR BEDWETTING AND METHOD OF USE THEREOF - Methods and compositions for treating bedwetting are disclosed. One method comprises administering to a subject in need thereof an effective amount of a pharmaceutical composition comprising one or more analgesic agents. | 2013-12-05 |
20130323289 | ANTIMICROBIAL SUBSTANCE, METHOD FOR PRODUCING SAME, AND ANTIMICROBIAL MATERIAL - Provided an antimicrobial substance that includes a base material layer, and a copper-tin alloy layer 5-200 nm in thickness disposed on the base material layer, the copper-tin alloy layer containing copper in an amount of more than 60 atomic percent but not more than 90 atomic percent, and containing tin in an amount of not less than 10 atomic percent but less than 40 atomic percent. The copper-tin alloy layer includes a Cu | 2013-12-05 |
20130323290 | ANTITOXIC FIBERS AND FIBROUS MEDIA AND METHODS FOR MANUFACTURING SAME - Antitoxic fibers and fibrous media contain impregnated material including an antitoxin. A method for producing antitoxic fibers and fibrous media includes impregnating a fibrous media by dipping in a dipping solution containing a concentrate of an antitoxin to form a fiber with impregnated material including an antitoxin. The impregnated material is at least about 1.0% to about 2.5% by weight of the fibers and includes additive chemical components including at least one of an anionic, cationic or nonionic component, an oil and/or an organic solvent, and an alcohol. The additives include those found in a spin finish. The antitoxin is in an amount of at least 0.1% by weight of the fiber. The manufacturing process can be applied to any woven or nonwoven media. Products with antitoxic properties formed therefrom include wound dressings, gowns, articles of clothing, surgical drapes, protective clothing, shoe covers, gloves, hair covers, air filters, including facemasks, privacy, hygienic products, curtains, medical tape, and wipes. | 2013-12-05 |
20130323291 | HYDROPHILIC AND NON-THROMBOGENIC POLYMER FOR COATING OF MEDICAL DEVICES - A hydrophilic copolymer is designed and synthesized by copolymerization of an acidic monomer and a second hydrophilic monomer. The copolymer is non-thrombogenic, hydrophilic and incorporates reactive functional groups. The copolymer can then be covalently attached to a primer/base coat through its functional groups, to form a durable lubricious coating on medical devices. A coating formed of the polymer on a surface is non-thrombogenic and non-cytotoxic. The coating shows good stability in gamma ray, e-beam and ethylene oxide sterilization. | 2013-12-05 |
20130323292 | Clog Resistant Insect Control Formulations Containing Pyrethrin, An Acetylenic Compound, And A Hydrocarbon Diene - Disclosed are pyrethrin-based insect control formulations which have been formulated to reduce wick clogging in dispensers which use heaters to drive an insect control active from the wick. Pyrethrum extract is mixed with an acetylenic compound, such as prallethrin or 3,5-dimethylhex-1-yn-3-ol, and a terminal diene compound such as myrcene or 1,3 hexadiene. Wick clogging side effects from using the pyrethrum are thereby suppressed. | 2013-12-05 |
20130323293 | GLP-1 ANALOGUE COMPOSITION FOR MICRONEEDLE DEVICES - A GLP-1 analogue composition for a microneedle device, including a GLP-1 analogue and at least one kind of solvent selected from the group consisting of water, glycerin, propylene glycol, ethylene glycol, 1,3-butylene glycol, and polyethylene glycol. | 2013-12-05 |
20130323294 | TISSUE REPAIR AND REPLACEMENT - Tissue fixation devices are provided. The devices include a first component and a second component, the components having different rates of in vivo degradation. The first component and second component are arranged so that, upon degradation of one of the components, the other component provides a scaffold into which bone can grow. | 2013-12-05 |
20130323295 | MONOMER SYSTEMS WITH DISPERSED SILICONE-BASED ENGINEERED PARTICLES - Provided are compositions containing engineered particles, and methods of making such engineered particles. Polymeric articles, such as contact lenses, prepared from such compositions are also provided. Such engineered particles are dispersible in hydrophilic systems such as monomer systems for preparation of contact lenses. Each of the engineered particles comprises a hydrophobic core and a hydrophilic shell. The hydrophobic core comprises a silicone-based polymer that can have multiple cross-links and/or polymer-polymer entanglement, and the hydrophilic shell is formed from a reactive stabilizer. A residue of the reactive stabilizer or a hydrophilic segment of the reactive stabilizer can form the shell. The particles have an average particle size of less than about 500 nm. | 2013-12-05 |
20130323296 | CARRIER FOR OROMUCOSAL, ESPECIALLY SUBLINGUAL ADMINISTRATION OF PHYSIOLOGICALLY ACTIVE SUBSTANCES - The present disclosure relates to a carrier for oromucosal, especially sublingual administration of physiologically active substances, especially of medicinal drugs, which consists of at least one elastic layer ( | 2013-12-05 |
20130323297 | Local administration of gallium compositions to treat pain - Provided are methods of treating pain, including neuropathic pain, in human and veterinary individuals. These methods employ locally administrable pharmaceutical gallium compositions, including pharmaceutical gallium compositions suitable for administration to the skin and mucous membranes. The compositions comprise pharmaceutically acceptable gallium compounds, such as gallium maltolate or gallium nitrate, together with pharmaceutically acceptable carriers suitable for local administration, including those suitable for topical administration. The administration of such compositions provides relief from pain, itching, allodynia, hyperalgesia, and related symptoms. | 2013-12-05 |
20130323298 | Amphoteric Liposome Formulation - The invention relates to compositions and methods to inhibit gene expression. In particular, the invention provides DNAi oligonucleotides sequestered by amphoteric liposomes for the treatment of cancer. | 2013-12-05 |
20130323299 | METHOD OF INDUCING NEUTRALIZING ANTIBODIES TO HUMAN IMMUNODEFICIENCY VIRUS - The present invention relates, in general, to human immunodeficiency virus (HIV), and, in particular, to a method of inducing neutralizing antibodies to HIV and to compounds and compositions suitable for use in such a method. | 2013-12-05 |
20130323300 | THERAPEUTIC COMPOSITION FOR TREATMENT OF GLIOBLASTOMA - The present invention is directed to compositions and methods for treating an animal diagnosed with Glioblastoma multiforme (GBM). | 2013-12-05 |
20130323301 | ENHANCED CANCER TREATMENT AND MONITORING USING RECOMBINANT VECTORS - This disclosure relates to replication competent viral vectors for treating cell proliferative disorders. The disclosure further relates to the use of such replication competent viral vectors for delivery and expression of a heterologous nucleic acid in normal and diseased tissues and methods and compositions that facilitate such delivery and expression to tissues in vivo and in vitro. The disclosure further relates to replication competent retroviral vectors for these uses and in conjunction with methods and compositions that facilitate in vivo therapeutics. | 2013-12-05 |
20130323302 | TREATMENT OF AMD USING AAV SFLT-1 - The present disclosure provides compositions and methods for the prevention or treatment of ocular neovascularization, such as AMD, in a human subject, by administering subretinally a pharmaceutical composition comprising a pharmaceutically effective amount of a vector comprising a nucleic acid encoding soluble Fms-related tyrosine kinase-1 (sFlt-1) protein to the human subject. | 2013-12-05 |
20130323303 | DRUG CARRIER AND PREPARATION METHOD THEREOF - A drug carrier is provided with a structure of a lipid shell enclosing aqueous micelles. The lipid shell includes lipid and emulsifier, in which the emulsifier encloses the lipid. The components of the aqueous micelles are phospholipids and amphiphilic chitosan, and the aqueous micelles enclose an aqueous solution containing a drug. Furthermore, the method of preparing the drug carrier is also provided. Therefore, with the pharmaceutical advantages of lipid-based nanoparticle included low drug leakage and the ability of to overcome the multiple drug resistance, this new formulation were further incorporated with the chitosan and featured with high payload efficiency. The features could enhance intracellular concentration of anti-cancer drug and oral bioavailability. | 2013-12-05 |
20130323304 | Methods For Enhancing The Release And Absorption of Water Insoluble Active Agents - Methods for enhancing the release and/or absorption of poorly water soluble active agents are described herein. The method involves dissolving, melting, or suspending a poorly water soluble active agent in one or more molten fatty acids, conjugated fatty acids, (semi-) solid surfactants of high HLB value, and/or hydrophilic polymers. The molten active agent mixture is then suspended and homogenized in a hydrophilic or lipophilic carrier to form microparticles suspended in the hydrophilic or lipophilic carrier. The particles suspended in the hydrophilic or lipophilic carrier can be encapsulated in a hard or soft gelatin or non-gelatin capsule. It is believed that the microparticles produced by the method described above will exhibit enhanced dissolution profiles. In vitro release studies of formulations containing cilostazol and fenofibrate showed 100% dissolution of cilostazol in 15 minutes and over 90% dissolution of fenofibrate in 35 minutes. | 2013-12-05 |
20130323305 | COMPOSITIONS AND METHODS COMPRISING ENERGY ABSORBING MATERIALS FOR FOLLICULAR DELIVERY - The present invention provides compositions comprising energy (e.g., light) absorbing submicron particles (e.g., nanoparticles comprising a silica core and a gold shell) and methods for delivering such particles via topical application. This delivery is facilitated by application of mechanical agitation (e.g. massage), acoustic vibration in the range of 10 Hz-20 kHz, ultrasound, alternating suction and pressure, and microjets. | 2013-12-05 |
20130323306 | INJECTABLE BIODEGRADABLE PARTICLES FOR CONTROLLED THERAPEUTIC AGENT RELEASE - In accordance with one aspect, embolic particles are provided that comprise a biodegradable polymer and a therapeutic agent, wherein the particles are configured such that, upon administration to a body lumen of a subject, the therapeutic agent is released from the time of administration up until a first point in time that ranges anywhere from about 1 week after administration to about 4 weeks after administration, at which point in time the therapeutic agent release ceases. The particles are also configured such that particles remain present in the body lumen from the first point in time at which therapeutic agent release ceases up to a second point in time that ranges anywhere from about 2 weeks to about 12 months after the first point in time, at which point the particles are completely degraded. Other aspects pertain to methods of making such particles. Still other aspects pertain to injectable compositions that comprise such particles and to methods of treatment that employ such injectable compositions. | 2013-12-05 |
20130323307 | SILDENAFIL-FREE BASE-CONTAINING FILM PREPARATION AND METHOD FOR PRODUCING SAME - The present invention provides a method for preparing a film comprising a high amount of a sildenafil free base uniformly dispersed therein and having a suitable thickness and size, as well as flexibility providing good handling stability and being not prone to breaking. The present invention also provides a sildenafil free base-containing film prepared from the method. | 2013-12-05 |
20130323308 | METHODS AND COMPOSITIONS FOR TREATING CONDITIONS RELATED TO LACK OF BLOOD SUPPLY, SHOCK AND NEURONAL INJURIES - A pharmaceutical composition comprising an amphiphilic emulsifier, a polar liquid carrier and, optionally, a lipid component. The amphiphilic emulsifier form free-moving, optionally lipid-carrying, micelles (LMs) in the polar liquid carrier. The pharmaceutical composition is free of hemoglobin and fluorocarbon and can be used for treating conditions related to lack of blood supply and to raise the blood pressure and correct hypovolemia. | 2013-12-05 |
20130323309 | Sustained Release Composition of Memantine - A sustained release pharmaceutical composition comprising; a core including memantine or its pharmaceutically acceptable salts and one or more pharmaceutical acceptable excipients, and a sustained release coating comprising a water insoluble substance and a water soluble substance where the ratio of the water insoluble substance to the water soluble substance is from about 1:0 to about 3:5:1, optionally containing an immediate release coating having memantine where the immediate release coating is applied over the sustained release coating. | 2013-12-05 |
20130323310 | SWELLABLE PARTICLES FOR DRUG DELIVERY - Swellable particles for delivering a working agent to the pulmonary system comprise a plurality of biodegradable particles each formed from a polymer network, each of the plurality of biodegradable particles having a mass mean aerodynamic diameter not exceeding 5 μm, the particles being swellable by hydration to a size that is greater than 6 μm volume mean diameter, and a working agent entrapped in the polymer network of each of the plurality of biodegradable particles. | 2013-12-05 |
20130323311 | COLLAGEN-TARGETED NANOPARTICLES - This invention relates to compositions comprising collagen binding peptides coupled to nanoparticles. The invention also relates to a method of imaging a collagenous matrix using a composition comprising collagen binding peptides coupled to nanoparticles. | 2013-12-05 |
20130323312 | Microspheres Including Oxidized Cellulose - A process for forming microspheres is disclosed. The process includes: forming a first plurality microspheres comprising at least one bioactive agent and modified cellulose; contacting the first plurality of microspheres with a solution of a biodegradable polymer to form a discontinuous phase liquid; contacting the discontinuous phase liquid with a continuous phase liquid to form an emulsion; and extracting a second plurality of microspheres from the emulsion, the second plurality of microspheres comprising the first plurality of microspheres. | 2013-12-05 |
20130323313 | Mucus Penetrating Gene Carriers - Nanoparticles gene carriers, particularly nanoparticle gene carriers which exhibit increased rates of diffusion through cystic fibrosis (CF) mucus, as well as methods of making and using thereof, are described herein. The nanoparticle gene carriers are formed from a nucleic acid complexed to one or more biocompatible, polycationic polymers. The nanoparticle gene carriers also contain one or more mucus resistant polymers. In a particularly preferred embodiment, the nanoparticle gene carrier is a nanoparticle formed from one or more nucleic acids, PEI, and a mucus-resistant/diffusive graft copolymer composed of a PEI backbone functionalized by one or more PEG side chains. The nanoparticle gene carriers can efficiently diffuse through CF mucus, and can effectively serve as a vehicle to administer one or more nucleic acids to a patient suffering from CF. | 2013-12-05 |
20130323314 | Novel Nanoparticles of Lactoferrin Useful for Preparing a Pharmaceutical Composition Facilitating Easy Delivery of the Drug and a Process for Preparing the Same - Novel nanoparticles of lactoferrin useful for preparing a pharmaceutical composition facilitating easy delivery of the drug contained therein wherein the sizes are in diameter in the range of 40 to 90 nanometers. | 2013-12-05 |
20130323315 | Microspheres Including Oxidized Cellulose - A process for forming microspheres is disclosed. The process includes contacting a solvent with a modified cellulose to form a solution; contacting the modified cellulose solution with at least one bioactive agent to form a discontinuous phase liquid; contacting the discontinuous phase liquid with a continuous phase liquid to form an emulsion; and contacting the emulsion with a third phase liquid to extract the solvent from the emulsion, thereby forming a plurality of modified cellulose microspheres. | 2013-12-05 |
20130323316 | INJECTABLE MICROSPHERES FOR DERMAL AUGMENTATION AND TISSUE BULKING - The present invention relates to elastic, hydrophilic and substantially spherical microspheres useful for dermal augmentation and tissue bulking. The invention provides injectable compositions comprising the microspheres and a biocompatible carrier for use in dermal augmentation. The present invention further provides methods of dermal augmentation and tissue bulking, particularly for the treatment of skin contour deficiencies, Gastro-esophageal reflux disease, urinary incontinence, and urinary reflux disease, using the injectable compositions. | 2013-12-05 |
20130323317 | INJECTABLE AND SWELLABLE MICROSPHERES FOR TISSUE BULKING - The present invention relates to injectable compositions comprising biocompatible, swellable, hydrophilic, non-toxic and substantially spherical microspheres useful for tissue bulking. The invention also relates to methods of tissue bulking, particularly for the treatment of Gastro-esophageal reflux disease, urinary incontinence, or urinary reflux disease, using the injectable compositions. | 2013-12-05 |
20130323318 | PROTEIN FREE SURFACTANT COMPOSITION FOR PULMONARY DISEASES AND A PROCESS FOR PREPARING THE SAME - A protein free surfactant composition comprising dipalmitoylphosphatidyl choline (DPPC) and eugenol having a ratio in the range of 10:5 to 4:2 with >99% airway patency in the presence of albumin, for treating acid lung injury, adult respiratory distress syndrome and meconium aspiration syndrome. | 2013-12-05 |
20130323319 | MODIFIED IMMUNE-MODULATING PARTICLES - The current invention involves the surprising finding that when carboxylated particles, such as carboxylated polystyrene, PLGA, or diamond particles are administered to subjects, inflammatory immune responses are ameliorated. Additionally, the present invention describes methods of treating inflammatory diseases by administering these same carboxylated particles. | 2013-12-05 |
20130323320 | pH SENSITIVE CARRIER AND PREPARATION METHOD THEREOF, AND pH SENSITIVE DRUG AND pH SENSITIVE DRUG COMPOSITION EACH CONTAINING THE CARRIER, AND METHOD FOR TREATING OR PREVENTING DISEASES USING THE SAME - A pH sensitive carrier which includes at least one pH sensitive compound selected from the group consisting of deoxycholic acid, cholic acid, ursodeoxycholic acid, chenodeoxycholic acid, hyodeoxycholic acid, C27 bile acid, glycodeoxycholic acid, glycyrrhizic acid, glycyrrhetinic acid and salts thereof, and at least one amphipathic substance selected from the group consisting of a phosphatidylcholine having 10 to 12 carbon atoms, a polyoxyethylene sorbitan monofatty acid ester having 12 to 18 carbon atoms, a sorbitan fatty acid ester having 16 to 18 carbon atoms, glycerol monooleate, glycerol dilaurate, glycerol distearate, glycerol dioleate, polyoxyethylene castor oil and α-tocopherol, and which is capable of developing a membrane disruptive function promoting effect. | 2013-12-05 |
20130323321 | PERSONAL HYGIENE COMPOSITION, ARTICLE OF MANUFACTURE AND METHOD COMPRISING CHAKRA STONE - Chakra stones or crystals are included as part of a personal hygiene or body cleansing composition as a novelty item or for aesthetic or decorative purposes. The chakra stones or crystals can also be used for their spiritual significance and for realigning, revitalizing, or balancing unbalanced chakra energies of the body. | 2013-12-05 |
20130323322 | METHOD FOR MAKING A GAS FROM AN AQUEOUS FLUID PRODUCT OF THE METHOD AND APPARATUS THERFOR - A method for producing a purified, stable, compressible gas from an aqueous fluid. The gas is suitable for a variety of uses and may also be infused into water which itself is useful for a variety of purposes | 2013-12-05 |
20130323323 | Therapeutic Method and Associated Compound for Augmenting the Liver's Metabolization of Oxygen-Modified Toxins - A therapeutic method and associated composition for counteracting the negative and toxic physiological effects of the consumption or production of oxygen-modified toxins, such as alcohol, congeners, and associated metabolites, by augmenting or restoring the liver's ability to metabolize said elements, thereby preventing or abating the negative effects of the toxins, such as the symptoms of a hangover in the case of alcohol. Oxygen-infused water with a high solubilization level combined with caffeine, sodium, potassium, dextrose, or flavoring elements provides a therapeutic and pleasant dose before, during, or after the intake of alcohol, thereby increasing the metabolism of oxygen-modified toxin, alcohol, congener, and associated metabolites, replenishing nutrient levels deteriorated by toxin-introduction or alcohol consumption, and treating hangover symptoms. | 2013-12-05 |
20130323324 | VANADIUM AND VANADYL AMINO ACID COMPLEXES - Compositions that include vanadium or vanadyl chelated to an amino acid are disclosed, particularly vanadium or vanadyl chelated to creatine, arginine, citrulline, taurine, phenylalanine, glutamine, glutathione, leucine, or combinations thereof. In addition, compositions that included blended forms of such chelates and/or vanadyl sulfate and one or more unbound amino acids. Still further, the compositions disclosed may further include one or more additional proteins, amino acids, vitamins, minerals, or combinations thereof, which impart an additional nutritional and/or therapeutic benefit to the composition. | 2013-12-05 |
20130323325 | COMPOSITION COMPRISING MIXED METAL COMPOUNDS AND XANTHAN GUM - The present invention provides a composition comprising (i) a mixed metal compound containing at least one trivalent metal selected from iron (lll) and aluminium and at least one divalent metal selected from of magnesium, iron, zinc, calcium, lanthanum and cerium, (ii) xanthan gum (iii) at least one of (a) polyvinyl pyrrolidone (b) locust bean gum (c) methyl cellulose wherein the composition has been irradiated with ionising radiation in an amount of at least 4 kGy. | 2013-12-05 |
20130323326 | METHOD FOR SUPPRESSING OR PREVENTING FIBROUS ADHESION FORMATION USING A MULTICOMPONENT AQUEOUS OXYCHLORINE COMPOSITION PREPARED ON-SITE - A composition and method are described for suppressing or preventing fibrous adhesion formation using a multicomponent aqueous oxychlorine composition. Fibrous adhesions typically form during healing of tissue, for example following a surgical procedure. A multicomponent oxychlorine composition is provided for irrigating the tissue which minimizes post-surgical adhesion formation, the composition containing both chlorine dioxide and chlorite ion, and a complex ion thereof. The chlorine dioxide level generally is in an effective range of ClO | 2013-12-05 |
20130323327 | METHOD FOR PREVENTING NASOLACRIMAL DUCT OBSTRUCTION - The invention is directed to a method for preventing nasolacrimal duct obstruction (NLDO) in a patient receiving high dose radioactive iodine for treatment of cancer. The method includes administering an effective amount of perchlorate anion to the eyes of the patient. | 2013-12-05 |
20130323328 | Pharmaceutical Preparation Containing Selenite or Selenite-Containing Compounds for Treating Cervical Dysplasia or Carcinomas - The invention relates to compositions containing selenite-containing compounds and pharmaceutically acceptable acids, selected from citric acid, acetic acid, malic acid, carbonic acid, sulphuric acid, nitric acid, hydrochloric acid, fruit acids or mixtures thereof, for use for treating cervical inflammations, dysplasia and/or carcinomas. | 2013-12-05 |
20130323329 | Method Of Using Rhein For Treating Fibrotic Conditions And Tumors - The present invention relates to a method of using an anthraquinone derivative namely 9,10-Dihyro-4,5-dihydroxy-9,10-dioxo-2-anthracenecarboxylic acid, or known as Rhein, for treating chronic pancreatitis induced fibrosis of the pancreas. More particularly, the present invention relates to a method of using Rhein, its derivatives and/or chemical variants as an anti-fibrotic agent. The present invention particularly relates to the suppression of pancreatic stellate cell activation for the management of chronic inflammatory, fibrotic and tumorigenic pathologies in the pancreas. | 2013-12-05 |
20130323330 | METHODS FOR INHIBITING PROSTATE CANCER BY KINASES AND ANGIOGENESIS INHIBITORY MECHANISMS OF BALL MOSS EXTRACT - A method of treating prostate cancer by administering a pharmaceutically-acceptable amount of a crude extract of the indigenous Jamaican plant Ball Moss ( | 2013-12-05 |
20130323332 | Hand and body moisturizing serum - An organic hand and body moisturizing serum comprised of; Sacha Inchi seed oil, Camellia seed oil, Sunflower seed oil, Jojoba oil, Palm stearic acid flakes, an emulsifying wax, Vitamin E d-alpha tocopherol, Lecithin, Rosemary oil, Tea tree oil, and Helichrysum oil or Evening Primrose seed oil. Another embodiment of the moisturizing serum would include Uviox made from hydrolyzed grape skin. | 2013-12-05 |
20130323333 | Nourishing Oil Composition, Pomade, Composition for Promoting Hair Growth, Shampoo, Conditioner, Hair Root Stimulator, and Methods for Making and Using the Same - Compositions for promoting hair growth can be formed using food related oils. The food related oils include meadowfoam seed oil, neem oil, sesame oil, camelina, flaxeed oil, and tamanu oil. The oil can be combined with lime peel essential oil and/or aloe vera to create various products. The products in an oil for treating the hair and scalp, a treatment for damaged hair and scalp, shampoo, conditioner, pomade and hair root stimulant. A method for making each product is described. In addition, a method for using each product is described. | 2013-12-05 |
20130323334 | Use Of Compositions For Preventing Chemotherapy And Radiotherapy Induced Alopecia (CRIA), Reducing CRIA Impact And Improving The Appearance Of Hair Re-Growth After CRIA - Compositions administered by topical route contain as active ingredients an extract of | 2013-12-05 |
20130323335 | PLANT EXTRACTS FOR THE TREATMENT AND PREVENTION OF INFECTIONS - A composition comprising a | 2013-12-05 |
20130323336 | METHOD OF INCREASING OMEGA-3 CONTENT IN POULTRY - A feed supplement for poultry consisting of distillers dried grains with solubles (DDGS) and flaxseed. The supplement is prepared using a dry extrusion process. Also described is a method of using the feed supplement to increase omega-3 fatty acids in poultry products, such as eggs. | 2013-12-05 |
20130323337 | NOVEL HERBAL COMPOSITION FOR THE TREATMENT OF WOUND HEALING, A REGENERATIVE MEDICINE - The present invention discloses a novel, synergistic, effective herbal composition as a regenerative medicine comprising combination therapeutically effective amounts of extracts obtained from | 2013-12-05 |
20130323338 | CONTROL OF INSECT PESTS - A bed lifting apparatus comprising a base and a support frame connected by at least one linkage arm, the at least one linkage arm including at least one biasing arrangement arranged to maintain the base and the support frame in a spaced apart relationship, wherein, in use, when a bed is located on the support frame, the bed is maintained in a spaced apart relationship from a floor surface. | 2013-12-05 |
20130323339 | COMPOSITION COMPRISING BANYAN TREE, LOTUS, AND CLOVER SERUM FRACTIONS (AGING) - The present invention relates to compositions comprising banyan tree, lotus, and clover serum fractions. A method of improving the appearance of aging skin may comprise the step of applying a composition comprising an effective amount of banyan tree serum fraction, lotus serum fraction, and clover serum fraction to a sign of aging on a skin surface, wherein the composition is applied for a period of time sufficient to improve the appearance of the aging skin. The method may include the step of identifying a sign of aging on a facial skin surface. | 2013-12-05 |
20130323340 | VEGETABLE EXTRACT AND METHOD OF USE AS AN ACTIVE PRINCIPLE IN THE PRODUCTION OF A PHARMACOLOGICALLY ACTIVE PRODUCT FOR THE TREATMENT OF TISSUE LESIONS, AND METHOD FOR OBTAINING THE EXTRACT - A resin extract from the | 2013-12-05 |
20130323341 | ANTIVIRAL COMPOSITIION - The present invention relates to a composition comprising extract of the plant | 2013-12-05 |
20130323342 | TIRE VULCANIZATION MOLD - A tire vulcanization mold comprises a mold body having an inner surface for molding a tire outer surface and at least one vent passage for the escape of gas in the mold during vulcanization, the vent passage with an inlet end and an outlet end, the inlet end being opened on the inner surface of the mold body, the outlet end communicating with an exterior of the mold body, wherein the vent passage communicates with the inner surface of the mold body at an angle of not less than 60 degrees, and less than 90 degrees with respect to a normal line perpendicular to the inner surface at the inlet end. | 2013-12-05 |
20130323343 | RECYCLABLE FORMWORK - There is disclosed to provide a recyclable formwork that can add the new function without spoiling the other functions of the recyclable formwork. The recyclable formwork includes: a main unit including a contact surface contacting with cast concrete, a non-contact surface being parallel and opposite to the contact surface, and a plurality of ribs outstanding from the non-contact surface to a side opposite to the non-contact surface and reinforcing the main unit; a case being housed between the plurality of ribs and being fixed on a side of the non-contact surface; and a circuit being stored in the case. A first highest point of the case at the side of the non-contact surface is not higher than a second highest point of upper ends of the plurality of the ribs. | 2013-12-05 |
20130323344 | INJECTION MOLDING APPARATUS HAVING THERMOSTAT ASSEMBLY - An exemplary injection molding apparatus includes a first mold defining a passage therein, a second mold engaging with the first mold, working fluid received in the passage of the first mold, and a thermal conductive member engaged in the first mold and thermally interconnecting the first mold and the working fluid. The first mold and the second mold cooperatively define a molding chamber therebetween adapted to receive injected molten material therein. The thermal conductive member transfers heat from the first and second molds to the working fluid when the first and second molds are hotter than the working fluid, and transfers heat from the working fluid to the first and second molds when the working fluid is hotter than the first and second molds. | 2013-12-05 |
20130323345 | FIXTURE FOR SHAPING A LAMINATE SUBSTRATE - A fixture for shaping a laminate substrate includes a trap ring, a base plate and a center button. The base plate includes a recess adapted to receive the laminate substrate. The center button is disposed in an opening in the base plate. The center button may be adjusted to shape the laminate substrate. | 2013-12-05 |
20130323346 | RECEPTACLE WITH MOUNT FEATURE - A method for forming a receptacle may include providing a mold having a forming surface and a recessed area defining part of the forming surface, the mold having sections that may be separated to open the mold and closed together to close the mold. A molten plastic parison may be provided into the mold when the mold is open, the mold may be closed and the parison may be expanded against the forming surface so that a portion of the parison enters the recessed area. The portion of the parison within the recessed area may be formed by moving a secondary forming feature relative to the mold and parison to define a mount feature. | 2013-12-05 |
20130323347 | DEMOLDING DEVICE - A demolding device ( | 2013-12-05 |
20130323348 | HEAT DISSIPATING ASSEMBLY AND MOLD HAVING THE SAME - A heat dissipating assembly of a mold includes an angular pin, a heat pipe, and a liquid passage passing through the angular pin. The angular pin defines a receiving chamber therein. The liquid passage passes through a lower portion of the receiving chamber of the angular pin. The heat pipe includes a condensing section, an evaporation section, and a connecting section interconnecting the condensing section and the evaporation section. The evaporation section is embedded in an upper portion of the receiving chamber opposite to the lower portion. The condensing section is located in the lower portion of the receiving chamber. A mold having the heat dissipating assembly is also provided. | 2013-12-05 |
20130323349 | Mold-Tool System Including Actuation Configured to Move Plate Assemblies Attached with Valve-Stem Assemblies of Runners - A mold-tool system ( | 2013-12-05 |
20130323350 | Orally dispersible multi-micronutrient dietary supplement composition and methods of using same - The present invention is directed to a novel orally dispersible multi-micronutrient dietary supplement in a tablet dosage form. Use of lipid encapsulated substrates, flavorings, sweeteners and bitter masking agents provides for a dosage that suppresses unpleasant tastes or aftertastes and imparts a pleasant mouth feel when the tablet disperses after being sucked or chewed for several minutes. The combination of lipid encapsulated substrates, oral disintegration and multiple daily dosing schedule provides for improved bioavailability of several crucial micronutrients. | 2013-12-05 |
20130323351 | Loquat Tea Composition - A loquat leaf tea composition and method of making the same is disclosed. The loquat leaf tea composition comprises a plurality of loquat leaves boiled and/or steeped in water. The loquat leaf tea composition is useful as an anti-oxidant rich health beverage that helps stabilize blood sugar levels and is beneficial to the liver and pancreas. | 2013-12-05 |
20130323352 | COMBINATION OF BIOAVAILABLE METHIONINE WITH AT LEAST ONE ESSENTIAL OIL - A method of improving livestock performance that includes administering a synergistic composition including a bioavailable methionine compound and at least one essential oil, as a feed additive to livestock. Improved livestock performance includes improved livestock growth, viability, homogeneity, production efficiency, or any combination thereof. | 2013-12-05 |
20130323353 | Feed Additive for Improved Pigment Retention - Extruded, formulated fish feed containing less than 10 percent by weight of ash, more than 20 percent by weight of fat, less than 20 percent by weight of starch-containing raw material, and pigment selected from the group of carotenoids, wherein the fish feed contains at least one water-soluble antioxidant selected from the group consisting of hydroxycinnamic acids and hydroxybenzoic acids, and wherein the fish feed contains up to 40 mg of pigment per kg feed of at least one pigment selected from the group consisting of astaxanthin and canthaxanthin. It is also described feeding fish with the feed. | 2013-12-05 |
20130323354 | COMPOSITION COMPRISING GLUTEN-FREE CEREAL FLOUR - A composition which comprises a) a gluten-free cereal flour, b) a hydroxypropyl methylcellulose or methyl cellulose, and c) a carboxymethyl cellulose, is useful for producing food products, such as gluten-free bakery products or gluten-free pasta. | 2013-12-05 |
20130323355 | COMPOSITION COMPRISING GLUTEN-FREE CEREAL FLOUR - A composition which comprises a) a gluten-free cereal flour, and b) a hydroxypropyl methylcellulose or methyl cellulose having particle sizes such that more than 50 weight percent of the hydroxypropyl methylcellulose or methyl cellulose particles are retained on a sieve of 150 micrometers mesh size and pass through a sieve of 420 micrometers mesh size is useful for producing food products, such as gluten-free bakery products or gluten-free pasta. | 2013-12-05 |
20130323356 | PACKAGING CONTAINER AND CONFECTIONERY PRODUCT CONTAINED IN PACKAGING CONTAINER - A packaging container is provided, which is configured such that a plurality of food pieces are contained in anteroposteriorly overlapping relation in a plurality of rows, and satisfies requirements for the compactness of the container and the pick-out easiness for picking out each of the food pieces. In a packaging container (A) having a slidable configuration, chewing gum pieces ( | 2013-12-05 |
20130323357 | CONTAINERS FOR FERMENTED SOYBEANS (NATTO), FERMENTED SOYBEANS WITHIN SAID CONTAINERS, AND METHOD FOR MANUFACTURING SAME - A natto (fermented soybeans) container | 2013-12-05 |
20130323358 | SUPPRESSED-POP POPCORN - Suppressed-pop popcorn is made by soaking popcorn kernels in a room temperature aqueous enzyme solution. The enzyme solution degrades the pericarp structure of the popcorn kernels and increases the moisture content within the popcorn kernels. As a result, the popcorn kernels partially pop when exposed to heat, yielding a crunchy, orally satisfying snack. | 2013-12-05 |
20130323359 | Preparation of Dough or Baked Products - The addition to dough of a combination of two lipolytic enzymes with different substrate specificities produces a synergistic effect on the dough or on a baked product made from the dough, particularly a larger loaf volume of the baked product and/or a better shape retention during baking. | 2013-12-05 |
20130323360 | PROBIOTICS-CONTAINING SOYBEAN OLIGOSACCHARIDE PRODUCT AND PREPARATION THEREOF - Provided is a soybean oligosaccharide product containing acidic soluble saccharides of soybean and probiotics, which at least include fructose, glucose, sucrose, raffinose, and stachyose, with a percentage of the combined weight of raffinose and stachyose being at least 46%, a weight percentage of fructose being not greater than 8.5%, and a weight percentage of glucose being not greater than 1.0%, based on the total weight of fructose, glucose, sucrose, raffinose, and stachyose. The soybean oligosaccharide product is prepared by extracting a soybean raw material with water under a pH of 3-6 and at a temperature of 50-70° C. to obtain an extract containing acidic soluble saccharides of soybean, and inoculating and fermenting the extract with probiotics that are able to decompose monosaccharides and disaccharides, but substantially not able to decompose trisaccharides or tetrasaccharides. | 2013-12-05 |
20130323361 | NUTRITIONAL COMPOSITIONS INCLUDING EXOGENOUS VITAMIN K2 - Nutritional composition and methods of making and using the nutritional compositions are provided. In a general embodiment, the present disclosure provides a nutritional composition including exogenous vitamin K2. The nutritional composition may further include an additional component selected from the group consisting of phosphorus, magnesium, zinc, iron, copper, manganese, calcium, vitamin D, osteopontin and combinations thereof | 2013-12-05 |
20130323362 | COMPOSITION AND METHOD FOR IMPROVING STABILITY AND EXTENDING SHELF LIFE OF PROBIOTIC BACTERIA AND FOOD PRODUCTS THEREOF - A composition comprising probiotic bacteria, the composition comprising: (a) a core composition containing the probiotic bacteria and a stabilizer, wherein the total amount of probiotics in the mixture is from about 10% to about 90% by weight of the core composition; (b) an innermost coating layer, layered on said core composition, comprising at least one hydrophobic solid fat or fatty acid having a melting point lower than 60° C.; (c) an intermediate coating layer layered on said innermost coating layer, which when present in an aqueous solution in the amount of 0.1% weight/weight over the weight of the solution, has a surface tension lower than 60 mN/m, when measured at 25° C.; and (d) an outer coating layer, layered on said intermediate coating layer; wherein the composition is in the form of particles; food products containing the composition and methods of preparation thereof. | 2013-12-05 |
20130323363 | INSECT ARTIFICIAL FEEDSTUFF - An insect artificial feedstuff is dry powder feedstuff composed of 1 to 50 percent by weight of a gelatinizing agent and 1 to 90 percent by weight of a powder foodstuff to further form gel by adding water having predetermined ratio, wherein the powder foodstuff comprises leaf powder formed by grinding at least one natural forage. Accordingly, other contents geld by utilizing the viscosity of the gelatinizing agent can be obtained to prepare artificial feedstuff having proper softness for different insects. The feeding rate of insect can be increased by the leaf powder, and the commonality of the insect artificial feedstuff can be effectively enhanced. | 2013-12-05 |
20130323364 | PREMIX FOR A FORTIFIED FOOD BLEND - The present invention relates to a vitamin, mineral and enzyme premix for a fortified food blend comprising an alpha-amylase and a glucoamylase to increase energy content, reduce viscosity, and improve taste of a porridge prepared from said fortified food blend. Furthermore, the invention relates to a high energy fortified food blend comprising a vitamin, mineral and enzyme pre-mix from which a high energy, low viscosity and tasty porridge can be prepared. It also relates to a porridge prepared form the fortified food blend according to the present invention. | 2013-12-05 |
20130323365 | ANIMAL FEEDS AND PROCESSES FOR PRODUCING SAME - The present invention relates to animal feed and processes for manufacturing the same. In particular, this invention relates to a high fibre, low density, mono-component (monoforage) product with high concentrations of long fibre particles derived from forage material, for feeding to pets and other animals and methods for producing the same. | 2013-12-05 |
20130323366 | POD AND PACKAGE FOR PREPARING A BEVERAGE BY CENTRIFUGATION - Pod for the preparation of a beverage in a centrifugal brewing device by feeding liquid through said pod and rotating the pod along a rotating axis “I” in the device to produce centrifugal forces on the liquid traversing the pod thereby forcing a beverage out of the pod by such centrifugal forces, wherein the pod comprises containment walls containing beverage ingredients; said containment walls being essentially made of porous filtering material and comprising a top wall from which a central funnel ( | 2013-12-05 |
20130323367 | EXTENDED LIFE FOOD PRODUCT - The present invention relates to a food product which is an ambient toastable sandwich with an extended shelf life and which can contain either savoury or sweet fillings As described herein for optimum taste performance the final food product is preferably toasted by the consumer. | 2013-12-05 |
20130323368 | SEAWEED-BASED FOOD PACKAGING COATING - A food packaging material comprises a paper, paperboard or cardboard substrate and a barrier coating on the substrate, wherein the barrier coating comprises the combination of starch, seaweed extract and paper fibers. | 2013-12-05 |
20130323369 | COMPACT MICROWAVABLE BAG - The present invention is a compact microwavable bag that includes a base bag that includes a top, a front side, a pair of sides, a bottom and an interior portion and a sealing strip that is disposed on the top of the base bag and utilizes a reclosable tongue and groove fastener to place one or more food items into the interior portion of the base bag. The compact microwavable bag also includes a venting aperture that releases steam that forms during microwaving the compact microwavable bag and one or more compartments that contain the one or more foods that are heated or cooked. | 2013-12-05 |
20130323370 | CONTAINER FOR THE PREPARATION OF BEVERAGE COMPRISING AN IMPROVED PERFORABLE FOIL AND METHOD FOR PREPARING A BEVERAGE - A portioned container ( | 2013-12-05 |
20130323371 | BABY FORMULA PREPARATION WITH WARMING SYSTEM AND CUSTOMIZED PODS - A technique for preparing baby formula includes containing an amount of powdered formula, premeasured to provide a single serving of baby formula, containing an amount of water, premeasured to provide at least a single serving of baby formula, heating the water, and dispensing both the premeasured formula and the water for providing a single serving into a bottle or other vessel when the water reaches a predetermined temperature. | 2013-12-05 |
20130323372 | METHOD FOR EXTRACTING MOLELCULES OF INTEREST FROM ALL OR PART OF A PLANT MATRIX - The invention relates to a method for extracting molecules of interest from a plant matrix, the method including the following steps: electrically processing the plant matrix by means of pulsed power; diffusing the molecules of interest from the processed plant matrix in a hydroalcoholic solvent and/or a solvent including ethyl acetate; and recovering the molecules of interest that were diffused. | 2013-12-05 |