49th week of 2009 patent applcation highlights part 45 |
Patent application number | Title | Published |
20090297571 | ANTIFUNGAL WALLBOARDS AND BUILDING MATERIALS AND METHODS FOR THE PRODUCTION THEREOF - The present invention relates to, inter alia, methods for the treatment of wallboards with fungicides and the treated wallboards. In particular, the invention relates to the treatment of wallboards with a fungicidally effective amount of fludioxonil. The invention also provides for the treatment of wallboards with synergistic combinations of fludioxonil and other fungicides. The invention also provides the treatment of building materials with fludioxonil and synergistic mixtures containing fludioxonil. | 2009-12-03 |
20090297572 | Drug-Containing Implants And Methods of Use Thereof - The present invention provides implants comprising a therapeutic drug and a polymer containing polylactic acid (PLA) and optionally polyglycolic acid (PGA). The present invention also provides methods of maintaining a therapeutic level of a drug in a subject, releasing a therapeutic drug at a substantially linear rate, and treating schizophrenia and other diseases and disorders, utilizing implants of the present invention. | 2009-12-03 |
20090297573 | Identifying and Modulating Molecular Pathways that Mediate Nervous System Plasticity - The present invention provides methods for identifying genes and pathways involved in plasticity. The invention applies some of these methods to identify genes that are differentially regulated in at least a portion of the nervous system of an individual subjected to conditions known to result in altered nervous system plasticity, i.e., dark rearing (DR) or monocular deprivation (MD). The genes are targets for pharmacological agents that modify plasticity. The invention also identifies biological pathways that are enriched in genes that are differentially regulated under conditions known to result in altered nervous system plasticity. The present invention further provides methods and compositions for modifying plasticity in the nervous system of a subject. The invention includes a method for modifying plasticity in the nervous system of a subject comprising administering a plasticity-modifying agent to the subject, wherein the plasticity-enhancing agent modulates a gene or pathway that is differentially regulated in developmental conditions that alter nervous system plasticity (e.g., DR or MD). The methods and compositions may be administered to a subject suffering from damage to the nervous system or from a neuropsychiatric disorder in order to enhance recovery, reorganization, or function of the nervous system. The methods optionally include administering a proteolysis-enhancing agent to the subject. | 2009-12-03 |
20090297574 | FLEXABLE SPIRALLY-ROLLED POLYMER TUBE FOR MONITORING AND TREATMENT OF BRAIN INJURIES - A flexible spirally-rolled polymer microtube for in vivo monitoring and treatment of brain injuries; the tube integrally comprising one or more microsensors and one or more microchannels, wherein the microsensors monitor one or more parameters and the microchannels are capable of delivering substances to the brain, removing substances from the brain, or both. | 2009-12-03 |
20090297575 | Implantable Drug Delivery Devices Having Alternating Hyrdrophilic And Amphiphilic Polymer Layers - An implantable drug delivery medical device with alternating hydrophilic and amphiphilic polymer layers and methods of using for the treatment of vascular disease are disclosed. | 2009-12-03 |
20090297576 | Local Delivery of PAR-1 Antagonists to Treat Vascular Complications - Described herein are methods and medical devices used to deliver bioactive agents locally to patients in need of treatment and/or prevention of cardiovascular conditions Local delivery of protease-activated receptor 1 (PAR-1) antagonists are described herein from implantable medical devices including, but not limited to, stents. | 2009-12-03 |
20090297577 | Local Delivery of Apolipoproteins and Their Derivatives - Disclosed are medical devices and methods for the local delivery and treatment of vascular conditions. The methods and treatments involve local delivery of at least one apolipoprotein. The vascular conditions described herein include plaque rupture, aneurysm, stenosis, restenosis, atherosclerosis, ischemic myocardial infarct and combinations thereof. | 2009-12-03 |
20090297578 | BIOSOLUBLE COATING COMPRISING ANTI-PROLIFERATIVE AND ANTI-INFLAMMATORY AGENT COMBINATION FOR TREATMENT OF VASCULAR DISORDERS - Drug-delivery systems such as drug-delivery stents having an anti-proliferative agent such as everolimus and an anti-flammatory agent such as clobetasol are provided. Also disclosed are methods of treating a vascular impairment such as restenosis or vulnerable plaque. | 2009-12-03 |
20090297579 | Control of Cells and Cell Multipotentiality in Three Dimensional Matrices - Methods for wound healing or tissue regeneration by means of cell and tissue engineering, including using three-dimensional matrices with cells therein. A three-dimensional matrix, optionally containing cells such as fibroblasts, is inserted Into the wound of a subject. An anti-inflammatory factor may also be used to reduce or suppress the immune response. The wound may be covered to limit exposure to gaseous oxygen, for example, using a membrane. An anticoagulant may also be applied. In addition, cells, such as fibroblasts or stem cells, when cultured within a three-dimensional matrix, under certain conditions, can be induced to form non-fibroblast multipotent cells. When stem cells are cultured in the three-dimensional matrix, at least some of the stem cells remain as stem cells and do not differentiate. Kits for promoting the control of cells within three-dimensional matrices are also disclosed. | 2009-12-03 |
20090297580 | SPINAL NUCLEUS PULPOSUS IMPLANT - The present invention relates to a spinal nucleus pulposus implant for use in the treatment of the intervertebral disc and in particular, to the use of a CD-RAP protein therefore. | 2009-12-03 |
20090297581 | MEDICAL DEVICES HAVING ELECTRODEPOSITED COATINGS - According to one aspect, the present invention provides implantable or insertable medical devices that comprise a conductive substrate and an electrodeposited coating over the substrate. The electrodeposited coating includes (a) one or more types of inorganic materials, (b) one or more types of polymeric materials and (c) optionally, one or more types of therapeutic agents. Still other aspects of the invention concern methods of making and using such devices. | 2009-12-03 |
20090297582 | VASCULAR OCCLUSION DEVICES AND METHODS - A device for in situ treatment of vascular or cerebral aneurysms comprises an occlusion device having a flexible, longitudinally extending elastomeric matrix member that assumes a non-linear shape to conformally fill a targeted site. The occlusion device comprises a flexible, longitudinally extending elastomeric matrix member, wherein the device assumes a non-linear shape capable of fully, substantially, or partially conformally filling a targeted vascular site. In one embodiment the vascular occlusion device comprises a first longitudinally extending structural element having a longitudinally extending lumen and an outer surface; a second longitudinally extending structural element extending through the lumen; and an elastomeric matrix member surrounding the outer surface, wherein the second structural member does not engage or attach to the first structural element or the elastomeric matrix. | 2009-12-03 |
20090297583 | POLY(ESTER AMIDES) FOR THE CONTROL OF AGENT-RELEASE FROM POLYMERIC COMPOSITIONS - The present invention generally encompasses a medical article, such as a medical device or coating comprising an agent or combination of agents, wherein the agent is distributed throughout a polymeric matrix. The polymeric matrix comprises an agent and a poly(ester amide) having a design that was preselected to provide a predetermined release rate of the combination of agents from the medical article. | 2009-12-03 |
20090297584 | BIOSOLUBLE COATING WITH LINEAR OVER TIME MASS LOSS - Implantable devices such as stents having a biosoluble coating with linear over time mass loss are provided. Also disclosed are methods of making and using the implantable device. | 2009-12-03 |
20090297585 | pH Modulated Films for Delivery of Actives - pH modulated films and methods of their preparation. The film compositions include at least one component having a non-neutral pH when combined with water; and a pH modulated polymer system selected to reduce or prevent synerisis when combined with the non-neutral component in combination with aqueous media. The films demonstrate a non-self-aggregating uniform heterogeneity. Desirably, the films disintegrate in water and may be formed by a controlled drying process, extrusion process, or other process that maintains the required uniformity of the film. | 2009-12-03 |
20090297586 | Tissue Products Having A Cooling Sensation When Contacted With Skin - Wiping products, such as facial tissues, contain a temperature change composition that can provide a cooling sensation when contacted with the skin of a user. The temperature change composition, for instance, can contain one or more phase change agents that undergo a phase change at slightly elevated temperatures. The phase change agents, in one embodiment, can have a relatively high heat of fusion. When undergoing a phase change, the phase change agents absorb heat and thereby provide a cooling feeling to the skin of a user. In one embodiment, the phase change agent comprises a straight chain hydrocarbon. Hydrocarbons useful as phase change agents include an octadecane, a nonadecane, a heptonoate, or mixtures thereof. | 2009-12-03 |
20090297587 | HYDROGEL WOUND DRESSING AND ITS METHOD OF PREPARATION - An improved hydrogel wound dressing and its preparation is disclosed. The ingredients used in the dressing are PAAS of 20˜30 wt %, PVA of 2˜6 wt % and water of 64˜78 wt %. The hydrogel wound dressings were formed by dissolution, casting films, radiation synthesis and sterilization. Compared with conventional hydrogel dressings the improved dressings displayed an enhanced degree of swelling. Cell growth factors may be incorporated into the dressings to be released slowly in the wound. | 2009-12-03 |
20090297588 | ANTIBIOTIC DRESSING FOR THE TREATMENT OF INFECTED WOUNDS - A silk protein membrane is described which is loaded with an antimicrobial compound and has a substantially non-granular ultrastructure which is (i) substantially devoid of micellar silk fibroin substructures and (ii) substantially devoid of pores when analysed by scanning electron microscopy at 0.2 μm resolution. The antimicrobial compound comprises, in one aspect of the invention, a host defense peptide. The silk protein membrane of the invention can be used in a method for the treatment of wounds and allows the wound dressing to be kept in place after removal of that wound dressing from a wound the wound has less than 10 | 2009-12-03 |
20090297589 | Method of treating burns using Avermectin compound - A method of treating a superficial or partial thickness burn caused by heat, or by UV or laser radiation is disclosed. The method includes topically applying a topical composition containing an avermectin compound to an affected area immediately after a burn occurs. The method further includes cooling the affected area with ice or water prior to application of the topical composition. Additionally, the method includes topically applying a second topical composition containing fluocinonide and salicylic acid on the affected area to further enhance anti-inflammatory effect of the avermectin compound on the damaged skin. | 2009-12-03 |
20090297590 | KETOTIFEN TRANSDERMAL DRUG DELIVERY SYSTEMS AND METHODS FOR TREATING OPHTHALMIC DISEASE - A ketotifen transdermal drug delivery system is provided. In certain embodiments, the system includes a support layer and a plaster layer provided on the support, wherein the plaster layer contains ketotifen freebase. Also provided are methods of using the delivery systems, e.g., for treatment of ophthalmic diseases, and kits containing the delivery systems. | 2009-12-03 |
20090297591 | Compositions And Methods For The Transdermal Delivery Of Pharmaceutical Compounds - The present invention is directed to compositions and methods for the transdermal delivery of a pharmaceutically active compound. In some embodiments, the addition of inert pharmaceutical ingredients in place of a portion of adhesive in a transdermal patch formulation increases the rate of skin permeation of a pharmaceutical compound. | 2009-12-03 |
20090297592 | Lipid Vesicle Composition - It is an object of the present invention to provide an enzyme preparation which is excellent in stability in blood (blood residence) and in transfer to a target organ (targeting property), and can be used effectively in enzyme replacement therapy or the like. | 2009-12-03 |
20090297593 | Use of Liposomes in a Carrier Comprising a Continuous Hydrophobic Phase as a Vehicle for Cancer Treatment - The invention compositions comprising a continuous hydrophobic phase and liposomes as a vehicle for delivery of an antigen capable of inducing a cytotoxic T lymphocyte (CTL) response and methods for their use in the treatment of cancer. | 2009-12-03 |
20090297594 | Oral Pharmaceutical Dosage Forms Comprising a Proton Pump Inhibitor and a NSAID - An oral pharmaceutical dosage form comprising an acid susceptible proton pump inhibitor and one or more NSAIDs in a fixed formulation, wherein the proton pump inhibitor is protected by an enteric coating layer. The fixed formulation is in the form of an enteric coating layered tablet, a capsule or a multiple unit tableted dosage form. The multiple unit dosage forms are most preferred. The new fixed formulation is especially useful in the treatment of gastrointestinal side-effects associated with NSAID treatment. | 2009-12-03 |
20090297595 | Method For Producing A Cross-Linked Substance, Especially In The Form Of A Microcapsule Or Layer - A device for producing a crosslinked substance, e.g., of crosslinked microcapsules ( | 2009-12-03 |
20090297596 | Nanoparticulate and Controlled Release Compositions Comprising a Platelet Aggregation Inhibitor - The present invention provides a composition comprising a platelet aggregation inhibitor, for example, cilostazol, or a salt or derivative thereof, useful in the treatment and prevention of ischemic symptoms. The invention provides a composition which comprises nanoparticulate particles comprising the platelet aggregation inhibitor and at least one surface stabilizer. The nanoparticulate particles have an effective average particle size of less than about 2000 nm. The invention provides also a composition that delivers a platelet aggregation inhibitor, or nanoparticles comprising the same, in a pulsatile or continuous manner. | 2009-12-03 |
20090297597 | Modified Release Ticlopidine Compositions - The invention relates to a multiparticulate modified release composition that, upon administration to a patient, delivers ticlopidine in a bimodal, multimodal or continuous manner. The multiparticulate modified release composition comprises a first component and at least one subsequent component, the first component comprising a first population of active ingredient containing particles and the at least one subsequent component comprising a second population of active ingredient containing particles. The invention also relates to a solid oral dosage form containing such multiparticulate modified release composition, and to methods for inhibiting platelet aggregation, inhibiting blood clotting, and reducing risk of stroke in a patient. | 2009-12-03 |
20090297598 | THERAPEUTIC COMBINATION - This invention relates to pharmaceutical combinations of amlodipine or a pharmaceutically acceptable acid addition salt thereof and atorvastatin or a pharmaceutically acceptable salt thereof, kits containing such combinations and methods of using such combinations to treat subjects suffering from angina pectoris, atherosclerosis, combined hypertension and hyperlipidemia and to treat subjects presenting with symptoms of cardiac risk, including humans. This invention also relates to additive and synergistic combinations of amlodipine and atorvastatin whereby those synergistic combinations are useful in treating subjects suffering from angina pectoris, atherosclerosis, combined hypertension and hyperlipidemia and those subjects presenting with symptoms of cardiac risk, including humans. | 2009-12-03 |
20090297599 | PHARMACEUTICAL COMPOSITIONS CONTAINING ROSUVASTATIN CALCIUM - A pharmaceutical composition is disclosed containing amorphous rosuvastatin calcium and at least one of the following stabilizing agents: magnesium hydroxide, calcium acetate, calcium gluconate, calcium glycerophosphate, or aluminum hydroxide, together with at least one pharmaceutically acceptable excipient. | 2009-12-03 |
20090297600 | NOVEL PHARMACEUTICAL FORMULATION CONTAINING A BIGUANIDE AND AN ANGIOTENSIN ANTAGONIST - A pharmaceutical dosage form comprising a controlled release component comprising an antihyperglycemic drug in combination with a second component comprising a angiotensin antagonist is herein disclosed and described. | 2009-12-03 |
20090297601 | Dosage form time-lagged of drugs for the therapy of insomnia - The invention is concerned with methods and compositions for treating insomnia, and provides a dosage form containing a drug substance useful in the treatment of insomnia, the dosage form being adapted to release said drug substance after a lag time during which substantially no drug substance is released, the lag time being about at least one hour after administration of the dosage form. | 2009-12-03 |
20090297602 | Modified Release Loxoprofen Compositions - The invention relates to a modified release composition comprising loxoprofen or a salt or derivative thereof that in operation delivers the drug in a pulsatile or continuous manner for the treatment of pain and/or inflammation. The composition may comprise a first loxoprofen component and one subsequent loxoprofen component, wherein the first loxoprofen component comprises an immediate release component and the subsequent loxoprofen component comprises a modified release component. | 2009-12-03 |
20090297603 | INTERSPINOUS DYNAMIC STABILIZATION SYSTEM WITH ANISOTROPIC HYDROGELS - Disclosed are embodiments of an interspinous dynamic stabilization system that can uniquely address the dynamic stabilization of a spinal segment and facet joint concurrently and that can be useful for drug delivery applications. The interspinous dynamic stabilization system comprises a relatively rigid casing and relies on the anisotropic expansion feature of specially manufactured hydrogels contained in the casing to resist and control the extension of the spine. In a surgical procedure, the casing is attached to adjacent spinous processes laterally or in an anterior-posterior direction. Dehydrated hydrogels are then inserted inside the casing, perhaps one by one in a minimally invasive manner. Upon absorption of fluid, the hydrogels swell axially in the preferred direction, eventually lifting the superior spinous process. As the casing is attached to the spinous processes, the interspinous dynamic stabilization system can also have enhanced stability against torsional and lateral bending. | 2009-12-03 |
20090297604 | METAL OXIDE HYDROGELS AND HYDROSOLS, THEIR PREPARATION AND USE - A process for preparing a hydrosol of one or more metal oxides, e.g. titanium dioxide, comprising preparing a metal alkoxide solution in a water-miscible organic solvent, e.g. an alcohol; providing an aqueous solvent; mixing the metal alkoxide solution with the aqueous solvent in a volume or weight proportion to form a single-phase aqueous sol colloid (hydrosol) of hydrated metal oxide in absence of a non-ionic block polymer surfactant. Also disclosed is a corresponding hydrogel; water-insoluble particles encapsulated in hydrated metal oxide and a process for their encapsulation; uses of the encapsulation products. | 2009-12-03 |
20090297605 | Composition And Device For In Vivo Cartilage Repair - The composition as described serves for in vivo cartilage repair. It basically consists of a naturally derived osteoinductive and/or chondroinductive mixture of factors (e.g. derived from bone) or of a synthetic mimic of such a mixture combined with a nanosphere delivery system. A preferred mixture of factors is the combination of factors isolated from bone, known as BP and described by Poser and Benedict (WO 95/13767). The nanosphere delivery system consists of nanospheres defined as polymer particles of less than 1000 nm in diameter (whereby the majority of particles preferably ranges between 200-400 nm) in which nanospheres the combination of factors is encapsulated. The nanospheres are loaded with the mixture of factors in a weight ratio of 0.001 to 17% (w/w), preferably of 1 to 4% (w/w) and have a release profile with an initial burst of 10 to 20% of the total load over the first 24 hours and a long time release of at least 0.1 per day during at least seven following days. The nanospheres are composed of e.g. ((D,L)lactic acid/glycolic acid)-copolymer (PLGA). The loaded nanospheres are e.g. made by phase inversion. The composition is advantageously utilized as a device comprising any biodegradable matrix in which the nanospheres loaded with the factor combination is contained. | 2009-12-03 |
20090297606 | GAMMA-LACTAM COMPOUNDS FOR PROMOTING BONE GROWTH - The present invention provides compounds, compositions and methods for promoting bone growth. Compounds useful in the methods of the present invention include compounds of Formula I, wherein each R | 2009-12-03 |
20090297607 | BIOMIMETIC POLYMERS AND USES THEREOF - Biodegradable polymers incorporating biomolecules and methods of their use are provided. Certain aspects provide biomolecules crosslinked with diglycidyl esters. The disclosed compositions have numerous applications including cellular regeneration, wound healing, and cellular differentiation. | 2009-12-03 |
20090297608 | BONE MARROW-DIRECTING DRUG DELIVERY MATERIALS AND THEIR APPLICATIONS - The present invention pertains to a bone marrow-directing drug delivery material that includes at least one fine particle, wherein the fine particle includes an anionic moiety on a surface of the particle. Also disclosed are uses of the material set forth herein for the prevention, treatment, or diagnosis of a disease of bone, cartilage, bone marrow, or a joint. Also disclosed are methods of preventing, treating, or diagnosing a disease of bone, cartilage, bone marrow, or a joint in a subject, involving administering to the subject a pharmaceutically effective amount of the material of the present invention. | 2009-12-03 |
20090297609 | Method of Biomolecule Immobilization On Polymers Using Click-Type Chemistry - The present invention provides a method for the covalent immobilization of biomolecules on polymers for delivery of the biomolecules, which has the advantage of being simple, highly efficient, environmentally friendly and free of side products relative to traditional immobilization techniques. The invention provides a modified micro/nanoparticle system, which uses a functionalized polymer formed into micro or nanoparticles to bind a molecule to the particles using uses facile chemistry, the Diels-Alder cycloaddition between a diene and a dienophile with the polymer being functionalized with one of them and the molecule with the other, or the Huisgen 1,3-dipolar cycloaddition between a terminal alkyne and an azide to bind the molecule to the particle. The molecules and/or other therapeutic agents may be encapsulated within the polymer particles for intravenous therapeutic delivery. The invention also provides a novel synthetic biodegradable polymer, a furan/alkyne-functionalized poly(trimethylene carbonate) (PTMC)-based polymer, whose composition can be designed to meet the defined physical and chemical property requirements. In one example, the particle system self-aggregates from functionalized PTMC-based copolymers containing poly(ethylene glycol) (PEG) segments. The composition of the copolymers can be designed to meet various particle system requirements, including size, thermodynamic stability, surface PEG density, drug encapsulation capacity and biomolecule immobilization capacity. | 2009-12-03 |
20090297610 | Composition and system to promote wound healing - An externally applied non-absorbent composition applied to a wound to promote the healing of skin. The composition contains a plurality of granulated minerals to provide a protective cover and to mask the wound. The composition, together with similar compositions, may be assembled as a system and layered above the wound to better bar undesired particles from contaminating the wound and to camouflage the wound site. The compositions of the system may each be applied via a dispensing brush which retains the composition in a reservoir and dispenses the composition to the skin through the brush bristles, preventing contamination of the composition from the wound. | 2009-12-03 |
20090297612 | HOMOGENEOUS, INTRINSIC RADIOPAQUE EMBOLIC PARTICLES - The invention is directed to embolic material comprising spherical, homogeneous and substantially non-porous radiopaque polymer particles based on at least one hydrophilic monomer and at least one radiopaque monomer according to general formula | 2009-12-03 |
20090297613 | Nanoparticles Designed for Drug Delivery - The present invention is directed to a method of producing nanoparticles by the miniemulsion method, said nanoparticles being made by adding a defined amount of stabilizer to the reaction system. The present invention is further directed to nanoparticles made by this method and their use for the treatment of diseases and conditions, requiring a pharmaceutical agent to cross one or more physiological barriers, in particular the blood-brain barrier. | 2009-12-03 |
20090297614 | NANOPARTICLES FOR PROVIDING IMMUNE RESPONSES AGAINST INFECTIOUS AGENTS - Nanoparticles for providing immune responses for the treatment or prophylaxis of infection by infectious agents such as viruses, parasites, bacteria, prions and fungi are described which comprises a core including metal and/or semiconductor atoms, wherein the core is covalently linked to a plurality of ligands, the ligands including a carbohydrate residue capable of stimulating an innate immune response, a T cell helper peptide and a danger signal. This platform may then be adapted by including one or more further ligands capable of producing a specific response to a target infectious agent. | 2009-12-03 |
20090297615 | NANOPARTICLES, METHODS OF MAKING SAME AND CELL LABELING USING SAME - There are disclosed polyhedral superparamagnetic nanoparticles and methods for making and using the nanoparticles. There are also disclosed coated and functionalized forms of the nanoparticles, methods of using nanoparticles and methods of treatment using nanoparticles. | 2009-12-03 |
20090297616 | Wound Care Composition - The present invention relates to a wound care composition comprising petrolatum ointment and zinc oxide. The wound care composition is effective at accelerating the healing of a wound resulting from cutaneous surgery and for reducing the appearance of scars. The amount of zinc oxide in the wound care composition is preferably about 1% to about 10%, which produces effective wound healing properties as well as a cosmetically elegant composition having a pleasing feel on the skin. | 2009-12-03 |
20090297618 | COMPOSITION BENEFICIAL FOR VISUOGNOSIS PERSISTENCE AND USE THEREOF - The present invention provides a formula food comprising lutien, zeaxanthin, zinc, and selenium beneficial for eye health and its application. The formula food is not only applied for dietary supplement tablets and capsules, but also applied for various formula milk powders, various functional beverages, various baked food. The formula food is conducive to the human eye health, especially beneficial for the improvement of visuognosis persistence of human eyes, helpful for asthenopia remission and the improvement of eye consciousness symptoms. | 2009-12-03 |
20090297619 | NANOPARTICULATE ANTICONVULSANT AND IMMUNOSUPPRESSIVE COMPOSITIONS - Described are controlled release nanoparticulate formulations comprising a nanoparticulate agent to be administered and a rate-controlling polymer which functions to prolong the release of the agent following administration. The novel compositions release the agent following administration for a time period ranging from about 2 to about 24 hours or longer. | 2009-12-03 |
20090297620 | Anti-Tumor Agent - Titanium oxide-antibody conjugated particles are disclosed, which are provided with selective binding ability without loss of dispersibility and catalytic activity by modifying titanium oxide conjugated particles, dispersed in a water-based solvent by a water-soluble polymer, with an antibody via a linker molecule bound without changing the nature of the water-soluble polymer. The present invention is an antitumor agent, comprising titanium oxide-antibody conjugated particles, wherein a linker molecule is bound to the titanium oxide surface of the titanium oxide conjugated particles, dispersed in a water-based solvent by a water-soluble polymer, via at least one functional group selected from a group consisting of a carboxyl group, an amino group, a diol group, a salicylic acid group, and a phosphoric acid group, and wherein the titanium oxide conjugated particles are further modified with an antibody via the linker molecule. This antitumor agent is concentrated in the affected area and can be utilized as an agent for diagnosis or for treatment in combination with ultrasonic irradiation. | 2009-12-03 |
20090297621 | Microparticles For The Treatment Of Disease - Microparticle-bioactive agent based treatments for local treatment of diseased tissues/organs are disclosed. | 2009-12-03 |
20090297622 | SEPARATION AND FORMULATION OF BIOACTIVE FRACTION AND SUBFRACTION FROM CAMEL URINE WORK AS ANTICANCER AGENT - A pharmaceutical composition includes an effective amount of bio-active fraction PMF or subfraction PMFK obtained from the lyophilized camel urine or cow urine which coded in publications with PM701, that is used as anti-cancer drug selected from an anticancer compound PM701, which are targeted selectively the cancer cells without affecting the normal cells. | 2009-12-03 |
20090297623 | FORMULATIONS, DEVICES AND METHODS FOR TREATING AND PREVENTING MUCOSITIS - The present invention is directed to compositions, devices, and methods for non-irritatively treating and preventing mucositis, such as chronic rhinosinusitis (CRS). Some aspects of the invention concern compositions comprising or consisting essentially of sodium phosphate buffer (e.g., sodium phosphate dibasic and sodium phosphate monobasic) and calcium carbonate; mucoadministration devices and kits containing such compositions; and methods for treating or preventing mucositis conditions such as CRS, comprising mucoadministering a composition of the invention to a subject in need thereof. | 2009-12-03 |
20090297624 | ARSENIC THERAPY FOR AUTOIMMUNE AND/OR INFLAMMATORY DISEASES IN MICE AND HUMANS - The invention relates to a method for treating and/or preventing autoimmune and/or inflammatory diseases, including the graft-versus-host disease, comprising administering to a patient in need thereof, a therapeutically effective amount of an arsenic compound or a pharmaceutically acceptable salt thereof. | 2009-12-03 |
20090297625 | AGENT FOR TREATING EYE DISEASES - The invention relates to chemical and pharmaceutical industry, in particular to developing ophthalmological agents having a wide spectrum of action based on vegetable components, vitamins, and trace elements. The agent for treating eye diseases comprises lyophilized blueberries, dihydroquercetin, beta-carotene, selexen, lutein, vitamins B | 2009-12-03 |
20090297626 | Methods for preparing metal oxides - The disclosed subject matter provides a method for preparing a metal oxide, the method includes (a) contacting a metal salt precursor with an alcohol to provide a metal oxide; and (b) removing the metal oxide from the alcohol. | 2009-12-03 |
20090297627 | Method and composition to improve performance during long term sporting event - A process to improve performance of an individual during a long term sporting event includes the steps of providing in ingestible form a plurality of doses of a first nutritional composition, each dose including a known equivalent concentration of calcium, magnesium, potassium, and zinc; providing in ingestible form a plurality of doses of a second nutritional composition, each dose of the second nutritional composition including a known equivalent concentration of calcium, magnesium, potassium, sodium, and zinc; establishing a dietary meal plan including the first nutritional composition for the individual to establish a urine pH in the range of 6.5 to 7.5; following the dietary meal plan to establish a urine pH in the range of 6.5 to 7.5; and, periodically measuring urine pH to confirm a urine pH in the range of 6.5 to 7.5. The process also includes the steps of, during training of the individual prior to the sporting event, generating data during one or more training intervals indicating changes in urine pH during the training interval; administering a selected amount of one or more of the doses of the second nutritional composition after a subsequent training interval, the subsequent training interval extending over a selected period of time; generating data indicating changes in urine pH after the second nutritional composition is administered during the subsequent training interval; and, repeating steps (i) to (iii) to determine a fixed quantity of the doses to maintain urine pH at a selected level in the range of pH 6.5 to pH 7.5 during the sporting event. The process also includes the steps of beginning to compete in the long term sporting event; and, at selected intervals during the long term sporting event, ingesting the fixed quantity of the doses to maintain the urine pH at a selected level in the range of pH 6.5 to pH 7.5. | 2009-12-03 |
20090297628 | Use of iron in the form of a stone extract as stimulus of the synthesis of collagen by skin fibroblasts - Use of a stone extract as stimulant of the synthesis of collagen by skin fibroblasts. | 2009-12-03 |
20090297629 | Systems, Methods, and Compositions Involving Chlorine Dioxide and Zeolite - Certain exemplary embodiments can provide one or more systems, machines, devices, manufactures, compositions of matter, and/or methods for, activities that can comprise, creating a composition comprising chlorine dioxide adsorbed in a zeolite, and/or releasing at least a portion of the chlorine dioxide from the composition, the released chlorine dioxide potentially useful for disinfection, decolorization, mildew control, and/or odor control. | 2009-12-03 |
20090297630 | Rectal Use of a Sodium Chloride Solution as an Intestinal Cleanser - Rectal use of a sodium chloride solution between 0.5% and 1.5% for rectal use, usable as an intestinal cleaner by simple mechanical action, used as an intestinal evacuator or cleaner in all those cases where intestinal evacuation is required, but without having any therapeutic effect, thus, avoiding side effects. | 2009-12-03 |
20090297631 | SALT COMPOSITIONS AND METHODS OF MAKING THE SAME - Disclosed is a method of preparing a salt composition comprising mixing a salt and an ingredient, pressing the salt and ingredient together under pressure to form an agglomerated salt and ingredient composition in the form of a sheet, briquette, pellet, flake or other form, and reducing the salt and ingredient composition into particulates having a desirable size, where the particulates form a substantially uniform blended product of the salt and the ingredient. In one embodiment, the salt composition may be sodium chloride or a sea salt and a seasoning or flavoring agent. | 2009-12-03 |
20090297632 | Device, Methods and Compositions to Alter Light Interplay with Skin - Device, methods, and compositions to alter light interplay with skin to change appearance of wrinkles, pigmentation, stretch marks, and cellulite as well as other skin conditions are described. The present invention relates generally to the treatment of soft tissue volume deficiency and loss, facial wrinkles, facial lines, pigmentation patterns not desired by the subject, stretch marks, cellulite and more particularly, to treatments for volume restoration or coloration correction using light reflective materials such as micas and the like. | 2009-12-03 |
20090297633 | PROCESS FOR PRODUCING SOLUTION HAVING CARBON DIOXIDE DISSOLVED THEREIN, APPARATUS THEREFOR AND CARBONATED WATER - The oxalic acid aqueous solution filled in an electrolytic tank is electrolyzed with an electrolyzer to produce carbonic acid gas, while ultrasonic wave from an ultrasonic generator is applied to the produced carbonic acid gas bubbles, to form micro bubbles, which is dissolved in said oxalic acid aqueous solution, so as to easily produce carbonic acid gas solution with micro carbonic acid gas bubbles dissolved at a low cost; said carbonic acid gas solution can substitute carbonated spring. | 2009-12-03 |
20090297634 | Compositions for sustrained release of nitric oxide, methods of preparing same and uses thereof - The invention provides compositions for releasing nitric oxide (NO) comprising a matrix that encapsulates nitric oxide. Nitric oxide is released when the composition is exposed to an aqueous environment. The invention further provides methods of preparing the compositions and uses of the compositions for treating infections and disorders. | 2009-12-03 |
20090297635 | Biodisintegrable Medical Devices - According to an aspect of the present invention, the present invention provides medical devices which contain one or more polymeric regions that are at least partially biodisintegrable in bodily fluid. These devices may be implanted or inserted into a subject for treatment of various diseases, disorders and conditions. | 2009-12-03 |
20090297636 | SENSORIC IMPRINTING - The invention concerns a method for exposing an infant to multiple different tastes of food products and stimulating the consumption of e.g. vegetables and fruit later in life. | 2009-12-03 |
20090297637 | Estrogenic Extracts of Anemarrhena Asphodeloides Bge. from the Liliaceae Family and Uses Thereof - Estrogenic extracts of | 2009-12-03 |
20090297638 | ESTROGENIC EXTRACTS OF Anemarrhena asphodeloides Bge. from the Liliaceae Family and USES THEREOF - Estrogenic extracts of | 2009-12-03 |
20090297639 | Cosmetic treatement method for fighting against skin ageing effects - The present invention relates to a method of cosmetic treatment for combating the effects of skin ageing and to novel cosmetic compositions which are particularly suitable for carrying it out. | 2009-12-03 |
20090297640 | Nutritional composition for increasing creatine uptake in skeletal muscle - A nutritional composition, the consumption of which provides a method for increasing creatine accumulation, building muscle size, increasing thermogenesis, reducing body fat mass leading to weight loss and/or improving muscular definition. The nutritional composition may include an aqueous solution of cinnamon and creatine. In addition, the nutritional composition may also include alpha lipoic acid. A method of manufacturing the nutritional composition is also provided. | 2009-12-03 |
20090297641 | HERBAL COMPOSITIONS FOR THE TREATMENT OF MUCOSAL LESIONS - The present invention provides therapeutic compositions comprising extracts of the plant species | 2009-12-03 |
20090297642 | Extractive of Piper Laetisipicum C.DC., its Process and its Uses - This is about a type of | 2009-12-03 |
20090297643 | BOTANICAL COMPOSITION AND ITS USES - This invention describes a novel combination of botanical components for relieving one or more symptoms related to hemorrhoids. The composition includes a therapeutically effective amount of an admixture including an extract from the bark of | 2009-12-03 |
20090297644 | HERBAL COMPOSITIONS FOR THE TREATMENT OF DISEASES OF THE ORAL CAVITY - The present invention relates to bioadhesive compositions for oral application, which comprise a curcuminoid substance as an active ingredient. The present invention also relates to method of using said bioadhesive composition for the prevention and treatment of periodontal diseases such as gingivitis and other periodontal diseases. | 2009-12-03 |
20090297645 | Fibroblast Activator and Method of Activating Fibroblast, Collagen Synthesis Promoter and Method of Promoting Collagen Synthesis, and Skin Antiaging Agent and Method of Preventing Aging of Skin - The present invention relates to a fibroblast activator comprising grape sap as an active ingredient, a method of activating a fibroblast, using grape sap, and a method of using grape sap as a fibroblast activator. The present invention further relates to a collagen synthesis promoter comprising grape sap as an active ingredient, a method of promoting collagen synthesis using grape sap, and a method of using grape sap as a collagen synthesis promoter. The present invention further relates to a skin antiaging agent comprising grape sap as an active ingredient, a method of preventing aging of skin using grape sap, and a method of using grape sap as a skin antiaging agent. The present invention provides highly safe and effective means of preventing aging. | 2009-12-03 |
20090297646 | FEEDS CONTAINING HOP ACIDS AND USES THEREOF AS SUPPLEMENTS IN ANIMAL FEEDS - Disclosed are methods for administering hop acids to alter the microbial population of the gastrointestinal tract of animals and to inhibit the growth of pathogenic organisms in the gastrointestinal tracts of animals. Also disclosed are methods of increasing weight gain, feed efficiency, milk production in mammals, and egg and meat production in poultry by administering hop acids. Also disclosed are animal feeds containing hops and hop acids. | 2009-12-03 |
20090297647 | Assays, method and compositions that exploit a mycobacterial iron acquistion pathway in cells - Assays for the identification of antibacterial agents that inhibit mycobacterial growth by interfering with the iron acquisition pathway in host cells are disclosed. Also disclosed are methods of inhibiting mycobacterial growth by interfering with iron uptake or by delivering antibacterial agents to mycobacteria in host cells through the iron uptake pathway, as well as certain compounds that are useful in the assay methods, and also as antibacterial agents. | 2009-12-03 |
20090297648 | Injection molding and temperature conditioning apparatus - An injection molding machine and a mold are used to form batches of hallow parts, such as PET preforms. An end of arm tool transfers the molded preforms from the mold to a temperature conditioning station having a conveyor. The batch of molded preforms is received and retained on the end of arm tool by an array of cooling tubes that are attached to a number of identical cooling tubes carrier devices. The conveyor is adapted to receive the carrier devices and the cooling tubes loaded with molded preforms from the end of arm tool. The conveyor is also adapted to transfer rapidly the carrier devices and the empty cooling tubes into the end of arm tool before the end of arm tool is moved back into the molding area to receive subsequent batches of molded preforms. | 2009-12-03 |
20090297649 | SHEET FILM FORMING ROLL, SHEET FILM CASTING APPARATUS, FINE PATTERN TRANSFERRING APPARATUS AND SHEET FILM - Disclosed is a sheet film forming roll ( | 2009-12-03 |
20090297650 | METHOD OF CONTROLLING INJECTION MOLDING MACHINE - When the number of rotations of a drive motor ( | 2009-12-03 |
20090297651 | NOZZLE BLOCK FOR ELECTROSPINNING - Disclosed is a nozzle block for electrospinning which is able to simultaneously electrically spin two or more different types of polymer spinning dopes, wherein a single-layer distribution plate for dividing a planar space within the nozzle block into two or more segments is installed within the nozzle block. The apparatus is simple because a single-layer distribution plate is installed instead of a conventional multi layer distribution plate. A hybrid nano fiber laminate can be prepared without any additional laminating procedure because two or more different polymer spinning dopes can be simultaneously electrically spun through different nozzles arranged within the same nozzle block. It is possible to prepare a hybrid nano fiber nonwoven fabric or filaments or the like composed of two or more types of nano fibers different in thermal properties or physical properties because their fiber diameter or polymer type are different from each other. | 2009-12-03 |
20090297652 | Polylactic acid polymer compositon for thermoforming, polylactic acid polymer sheet for thermoforming, and thermoformed object obtained therefrom - In order to provide a polylactic acid polymer composition to be thermoformed and a polylactic acid polymer sheet to be thermoformed which show good formability during thermoforming while maintaining impact resistance and heat resistance, and a thermoformed article obtained from the polylactic acid polymer sheet, according to the present invention, a polylactic acid polymer composition is used which comprises a mixture of an essentially amorphous polylactic acid polymer and a crystalline polylactic acid polymer, wherein the essentially amorphous polylactic acid polymer is present at the rate of more than 50% of the crystalline polylactic acid. | 2009-12-03 |
20090297653 | TWO-STAGE REACTION INJECTION MOLDED GOLF BALL - Various reaction injection molding (“RIM”) processes and molding equipment are disclosed. In particular, a multi-stage molding process and molding assembly is disclosed for the production of layers or cores on golf balls. The process utilizes a collection of molds, including shuttle molds and/or molding assist members, that readily enables reaction injection molding of layer(s) on golf ball cores or intermediate golf ball assemblies. | 2009-12-03 |
20090297654 | INJECTION STRETCH BLOW MOLDING SYSTEM WITH ROTATING AND LINEAR CONVEYING FUNCTIONS - An injection stretch blow molding system with rotating and linear conveying functions includes a lifting and rotating mechanism, an injecting mechanism, a conveying mechanism, an extending and blowing mechanism installed at a third operating position, and a pushing mechanism installed at a second operating position. The lifting and rotating mechanism has a lifting seat, a rotating plate, and two bottleneck seats. Each of the two bottleneck seats has at least one bottleneck mold, with the rotation of the rotating plate, positions of the two bottleneck seats are selectively interchanged between a first and the second operating positions. The injecting mechanism has a female mold and a core mold installed at the first operating position. The conveying mechanism has a conveying seat connecting the two bottleneck seats whose bottleneck mold clamps a preform is installed at the second operating position. The conveying seat is driven by a convey driving device. | 2009-12-03 |
20090297655 | Linearly Displaceable Rotary Drive For A Plastic Injection-Molding Machine - The invention relates to a combination drive for a plastic injection-molding machine having a rotary drive ( | 2009-12-03 |
20090297656 | Liquid Formulation Based On a Guanidinoacetic Acid Component - The present invention relates to a liquid formulation for human and animal nutrition, consisting of an aqueous solution, a guanidinoacetic acid component and at least one methyl group donor from the group of choline, methionine and betaine. In addition to the free guanidinoacetic acid, it is also possible to use salts, adducts and/or complexes as the guanidinoacetic acid component, which can additionally be combined with further physiologically active compounds. Since the guanidinoacetic acid component is present in dissolved form, formulations including those in the form of mineral water, lemonade, alcoholic drinks and drinking water formulations are envisaged. It has been found that, surprisingly, the guanidinoacetic acid component present in this liquid formulation has very good stability and is converted very rapidly to creatine in the body. | 2009-12-03 |
20090297657 | O-acetylhomoserinesulfhydorelace gene and use thereof - The present invention relates to a brewery yeast having controlled hydrogen sulfide-producing capability, a process for producing alcoholic beverages with controlled hydrogen sulfide amount. More particularly, the present invention relates to a yeast whose hydrogen sulfide-producing capability that increases the product flavor is controlled by enhancing the expression level of MET17 gene encoding brewery yeast O-acetylhomoserinesulfhydorelace Met17p, particularly non-ScMET17 gene specific to lager brewing yeast, and to a method for producing alcoholic beverages with said yeast. | 2009-12-03 |
20090297658 | Alcoholic liquor additives and method for preparing the same - Disclosed are an alcoholic liquor additive and a method for preparation thereof. The alcoholic liquor additive includes 18 to 22 wt. % of mulberry fruits, 8 to 12 wt. % of citron fruits, 4 to 6 wt. % of cucumber, 2 to 4 wt. % of | 2009-12-03 |
20090297659 | ENZYMATIC DOUGH CONDITIONER AND FLAVOR IMPROVER FOR BAKERY PRODUCTS - Novel yeast-raised and other bakery products and methods of making those products are provided. The products are formed from dough comprising very high levels of maltogenic amylase. These levels result in improved properties in the final baked product, including improved flavor, longer shelf life, and higher baked volumes. In one embodiment, the level of sugar included in the dough can be substantially reduced compared to prior art quantities, while still achieving a sweet product. The invention also allows certain chemicals such as sodium stearoyl lactylate and azodicarbonamide to be entirely eliminated from the dough. | 2009-12-03 |
20090297660 | Cheese Products Containing Galacto-Oligosaccharides And Having Reduced Lactose Levels - The processes described herein are directed to cream cheese products containing galacto-oligosaccharides and having significantly reduced lactose levels. More specifically, lactose-containing dairy substrates are contacted with lactase enzyme(s) having hydrolytic and trans-galactosylation activities effective for converting at least 20 percent of the lactose in the dairy substrate to galacto-oligosaccharides. The enzyme-treated dairy substrate is then processed into galacto-oligosaccharide containing cream cheese products having reduced lactose levels. The cream cheese products provided herein have excellent nutritional and organoleptic properties. | 2009-12-03 |
20090297661 | Methods For Flavor Enhancement - The present invention is directed to methods of generating Umami flavor in-situ in food and beverage compositions by treating food or beverage compositions with an enzyme composition having glutamate releasing activity. The glutamate residues, free form, or C or N terminal short peptides produce Umami taste enhancement in the treated food or beverage. The present invention is also directed to methods of generating Umami flavor in-situ in food and beverage compositions by treating food or beverage compositions with an enzyme composition having aspartate releasing activity. The aspartate residues, free form, or C or N terminal short peptides produce Umami taste enhancement in the treated food or beverage. | 2009-12-03 |
20090297662 | PROCESS FOR PRODUCING SEASONING - Provided is a process for producing a seasoning having an excellent roast meat like flavor without unpleasant odor derived from yeast and burnt odor derived from saccharide. The process comprises the steps of mixing a yeast extract containing at least one of cysteine, cystine, methionine, glutathione, γ-glutamylcysteine, cystebylglycine, and salts or hydrates thereof with saccharide and/or a nucleic acid-related substance to prepare a mixture; and heating the mixture under different pH conditions. | 2009-12-03 |
20090297663 | BREAD IMPROVER - Structural properties of bread and other bakery products based on leavened flour are improved by incorporating into the flour at least 0.1 wt. % of a polysaccharide which is characterised by a molecular weight of at least 10 | 2009-12-03 |
20090297664 | LOW TEMPERATURE FORMING OF FEEDS - This application relates to a method and composition for low temperature forming of starch based and/or protein based feeds. It is particularly related to human or animal feeds containing inactivated probiotics, prebiotics, enzymes, inactivated yeasts, botanical extracts and dairy components. The low temperature extrusion process provides a means for the formation of a suitable starch and/or protein-based structure, as a carrier for temperature and/or pressure sensitive ingredients. | 2009-12-03 |
20090297665 | Compositions containing non-polar compounds - Provided herein are compositions and methods for preparing foods and beverages that contain additives, such as nutraceuticals, pharmaceuticals, and supplements, such as essential fatty acids, including omega-3 fatty acids, omega-6 fatty acids, conjugated fatty acids, and other fatty acids; phytochemicals, including phytosterols; other oils; and coenzymes, including Coenzyme Q10, and other oil-based additives. | 2009-12-03 |
20090297666 | Lolipop and device for the manufacturing thereof - Lollipop having a head ( | 2009-12-03 |
20090297667 | Packaging of Meat Products with Modified Atmospheres - A product packaging comprises a base, a lid, a meat product, and a gas within a space between the base, the lid, and the meat product. The base and the lid form a cavity having a first volume. The meat product has a first color and a second volume. The second volume is smaller than the first volume. The cavity is configured and arranged to receive the meat product. The space has a third volume that is the difference between the first volume and the second volume. The gas within the space comprises no greater than 30% carbon monoxide, and at least one of the base and the lid has an oxygen transmission rate of 0.1 to 15 cc of oxygen per package in 24 hours so that in 18 to 90 days the first color of the meat product has noticeably changed to a second color. | 2009-12-03 |
20090297668 | System and Methods for Automatic Preparation of Substitute Food Items - A food emulator for the production of an edible article that can substitute for a food item and that includes a carrier element formed of an edible material and an information element disposed on one or more surface of the carrier element. The one or more information element includes information related to the food item. The information may be one or more of a flavoring agent, a coloring agent or a texturing agent, for example. Different types and combinations of information may be provided by way of the information element and/or the carrier element to substitute for food items. | 2009-12-03 |
20090297669 | FOOD-GRADE TONER - A toner consists essentially of food-grade components. Because the toner consists essentially of food-grade components, it can be used to provide a coating or create an image on food products, including those intended for human or animal consumption. | 2009-12-03 |
20090297670 | SWEETENER COMPOSITIONS - The invention provides a sweetener composition comprising a core nano particle in association with a sweetener carbohydrate. | 2009-12-03 |
20090297671 | Infusion Method for Vacuum Fried Fruit Leveraging - A method for infusing fruits and vegetables with prebiotic soluble fibers in the form of either short chain fructooligosaccharides or dextrins. Fruits and vegetables are submerged in an infusion solution of prebiotic soluble fiber, and undergo both atmospheric and vacuum infusion processes. The infusion solution is maintained at a temperature of between about 45° F. to about 50° F. and at a Brix of about 30° to about 60°. Vacuum (low pressure) pulses are applied to the product to expedite solids infusion (mass transfer) and thereby decrease infusion time and the product is subsequently vacuum fried to attain a great-tasting, fiber-enriched and aesthetically-pleasing fruit or vegetable product with reduced sweetness, good texture, and an enhanced natural taste with less than 2% moisture by weight and a significantly long shelf-life of up to 12 months. | 2009-12-03 |
20090297672 | Process for improving shelf life of refrigerated foods - A process for producing a food product having an extended refrigerated shelf life comprising sealing food in a container; heating the food in the sealed container at a desired temperature for a desired period to inactivate undesirable microorganisms likely to be present in the food; rapidly cooling the heated food to substantially prevent germination of undesirable microbial spores likely to be present in the food; wherein undesirable microorganisms present in the food are substantially inactivated and other microorganisms are prevented from re-contaminating the food after processing so that the food product has an extended refrigerated shelf life. | 2009-12-03 |