48th week of 2010 patent applcation highlights part 46 |
Patent application number | Title | Published |
20100304298 | NEGATIVE PHOTOSENSITIVE MATERIAL, PHOTOSENSITIVE BOARD EMPLOYING THE NEGATIVE PHOTOSENSITIVE MATERIAL, AND NEGATIVE PATTERN FORMING METHOD - A negative photosensitive material is provided which has a lower linear expansion coefficient and a lower hygroscopic expansion coefficient and is excellent in gradational patternability and PI etchability in patterning. The negative photosensitive material comprises: | 2010-12-02 |
20100304299 | CHEMICALLY AMPLIFIED POSITIVE PHOTORESIST COMPOSITION - A photoresist composition. The composition has the following: (a) one or more resin binders that include one or more acid sensitive groups and that are substantially free of phenolic groups protected by acetal or ketal groups; (b) one or more photo acid generators, that, upon exposure to a source of high energy, decompose and generate a photoacid strong enough to remove the one or more acid sensitive groups; (c) one or more ionic non-photosensitive additives including an iminium salt; and (d) one or more solvents. There is also a process for patterning relief structures on a substrate employing the photoresist composition. | 2010-12-02 |
20100304300 | PHOTOSENSITIVE COMPOSITION AND PATTERN-FORMING METHOD USING THE PHOTOSENSITIVE COMPOSITION - A photosensitive composition comprises (A) a sulfonium or iodonium salt having an anion represented by one of formulae (I) and (II): | 2010-12-02 |
20100304301 | Negative resist composition and patterning process using the same - There is disclosed a negative resist composition comprising (A) a base polymer which is soluble in alkali and which is insolubilized in alkali by an action of an acid; and/or a combination of a crosslinking agent and a base polymer which is soluble in alkali and which is reacted with the crosslinking agent by an action of an acid to thereby be insolubilized in alkali, (B) an acid generator, and (C) a nitrogen-containing compound as a basic component; wherein the polymer to be used as the base polymer is: a polymer, which is obtained by polymerizing two or more kinds of monomers represented by the following general formula (1), or which is obtained by polymerizing a monomer mixture containing one or more kinds of monomers represented by the general formula (1) and one or more kinds of styrene monomers represented by the following general formula (2). | 2010-12-02 |
20100304302 | CHEMICALLY AMPLIFIED RESIST COMPOSITION AND PATTERN FORMING PROCESS - A chemically amplified resist composition comprises a polymer comprising units having polarity to impart adhesion and acid labile units adapted to turn alkali soluble under the action of acid. The polymer comprises recurring units having formula (1) wherein R | 2010-12-02 |
20100304303 | Novel Sulfonic Acid Salt and Derivative Thereof, Photoacid Generator Agent, and Resist Material and Pattern Formation Method Using the Photoacid Generator Agent - Disclosed is a fluorinated sulfonic acid salt or fluorinated sulfonic acid group-containing compound having a structure represented by the following general formula (A). | 2010-12-02 |
20100304304 | METHOD FOR MAKING LITHOGRAPHIC PLATES - Method for producing an imaged lithographic printing plate comprising the step of developing an imagewise exposed negative working precursor with a developer comprising an alkylene oxide derivative of formula (A), wherein R | 2010-12-02 |
20100304305 | RESIST UNDERLAYER FILM FORMING COMPOSITION CONTAINING POLYMER HAVING NITROGEN-CONTAINING SILYL GROUP - There is provided a resist underlayer film for lithography causing no intermixing with a photoresist and having a dry etching rate higher than that of the photoresist, and a resist underlayer film forming composition for forming the underlayer film. A resist underlayer film forming composition for lithography comprising: a polymer containing a partial structure of Formula (1): | 2010-12-02 |
20100304306 | FLEXIBLE MICRO/NANOFLUIDIC DEVICES - The present invention relates to a method for manufacturing micro/nanofluidic devices that incorporate overhanging micromechanical and metal components monolithically integrated with the fluidic circuitry. | 2010-12-02 |
20100304307 | EXPOSURE APPARATUS AND DEVICE MANUFACTURING METHOD - While one ends of ropes are respectively tied to a −Y side leg section and a +Y side leg section of a frame caster, the other ends of the ropes hang down in a −Z direction via a plurality of pulleys fixed to the upper sections of frames that are each separated from an apparatus main body, and a weight having a weight corresponding to a half the weight to be reduced is tied to each of the other ends. In this case, even if the apparatus main body oscillates in vertical or lateral directions (normal directions of the pulleys) owing to the action of a vibration isolation table, the position of the weight only vertically moves by rotation of the pulleys, and the reduced amount of the apparatus weight does not vary. Further, since any coil springs are not used, sympathetic vibration with the apparatus main body and the vibration isolation table does not occur, which allows the attenuation characteristics of the vibration isolation table to be improved. Therefore, the exposure apparatus can be increased in size without inducing the cost rise. | 2010-12-02 |
20100304308 | PROCESS FOR THICK FILM CIRCUIT PATTERNING - The invention relates to forming an electrically functional pattern on a substrate and to a process for using a photosensitive element in combination with a sheet having a thick film composition applied to a support. The process for forming a pattern having electrically functional properties on a substrate comprises the steps of: (a) providing a photosensitive layer having a tacky surface disposed on a substrate; (b) image-wise exposing the photosensitive layer to form an imaged layer having tacky and non-tacky areas; (c) applying a sheet comprising at least one layer of a thick film composition disposed on a support to the imaged layer wherein the imaged layer is in contact with the thick film composition of the sheet; (d) heating the transfer sheet and the photohardenable layer to increase the adhesive strength between the thick film composition and tacky areas of the imaged layer; (e) removing the support wherein the thick film composition remains on the support in the non-tacky areas of the imaged layer and the thick film composition substantially adheres to the tacky areas of the imaged layer forming a patterned article; and (f) heating the thick film composition of the patterned article. | 2010-12-02 |
20100304309 | METHOD AND APPARATUS FOR PHOTOIMAGING A SUBSTRATE - A method includes providing a substrate having a layer of photosensitive material thereon and a mask having contiguous first, second, and third portions; and sequentially: i) scanning the first portion with a light beam at a first rate and subsequently impinges on the photosensitive material at an exposure zone; ii) fixing the scanning within the second portion; and iii) resuming scanning through the third portion. Throughout the process the substrate moves through the exposure zone. An apparatus for carrying out the process includes a light beam source, a mask mount, a mask stage, a conveyor assembly, and at least one optical element for manipulating the light beam into a rectangular light beam. | 2010-12-02 |
20100304310 | EXPOSURE APPARATUS, EXPOSURE METHOD, AND DEVICE MANUFACTURING METHOD - An exposure apparatus that exposes a substrate includes: an optical system that includes an emission surface from which an exposure light is emitted; a first surface that is disposed in at least a part of a surrounding of an optical path of the exposure light emitted from the emission surface; a second surface that is disposed in at least a part of a surrounding of the first surface and at a position lower than the first surface; a space portion into which a liquid can flow via a first aperture between the first surface and the second surface and which is opened to the atmosphere via a second aperture different from the first aperture; and a first recovery portion that recovers at least a part of the liquid flowing into the space portion. Here, the emission surface, the first surface, and the second surface are opposed to the surface of the substrate in at least a part of the exposure of the substrate, and the substrate is exposed with the exposure light from the emission surface via the liquid between the emission surface and the surface of the substrate. | 2010-12-02 |
20100304311 | METHOD OF PRODUCING RESIST PATTERN - A method of producing a resist pattern includes the steps of: forming a resist layer on the semiconductor substrate; performing a first exposure process on the resist layer; performing a first developing process for developing the resist layer to form a first resist pattern having an excess region; performing a first cleaning process; performing a second exposure process on the first resist pattern; performing a second developing process on the first resist pattern to remove the excess region from the first resist pattern so that a second resist pattern corresponding to the specific resist pattern is formed; and performing a second cleaning process. | 2010-12-02 |
20100304312 | CLEANING LIQUID USED IN PHOTOLITHOGRAPHY AND A METHOD FOR TREATING SUBSTRATE THEREWITH - It is disclosed a cleaning liquid for stripping and dissolving a photoresist pattern having a film thickness of 10-150 μm, which contains (a) 0.5-15 mass % of a quaternary ammonium hydroxide, such as tetrapropylammonium hydroxide and tetrabutylammonium hydroxide, (b) 65-97 mass % of a water-soluble organic solvent, such as dimethylsulfoxide or a mixed solvent thereof with N-methyl-2-pyrrolidone, sulforane, etc., and (c) 0.5-30 mass % of water, and a method for treating a substrate therewith. | 2010-12-02 |
20100304313 | Process Solutions Containing Surfactants - Process solutions comprising one or more surfactants are used to reduce the number of defects in the manufacture of semiconductor devices. In certain preferred embodiments, the process solution of the present invention may reduce post-development defects such as pattern collapse when employed as a rinse solution either during or after the development of the patterned photoresist layer. Also disclosed is a method for reducing the number of pattern collapse defects on a plurality of photoresist coated substrates employing the process solution of the present invention. | 2010-12-02 |
20100304314 | LOW NOX MIXED INJECTOR - The invention relates to
| 2010-12-02 |
20100304315 | Combination Safety Valve and Ignition Trigger For Gas Burners - Presented is a system and method for permitting concurrent actuation of a gas safety valve and an ignition trigger for igniting gas burners. The combination safety valve and ignition device for gas burners permits both the start of a flow of flammable gas to a burner and the ignition of the flammable gas via operation of a single button or other actuator. | 2010-12-02 |
20100304316 | SYSTEM AND METHOD FOR CONTROLLING THE CALORIE CONTENT OF A FUEL - The present invention pertains generally to a system and method for providing fuel having a desired calorie content to a combustion engine over a range of operating levels. The system mixes a first fuel from a first fuel supply pipe with a second fuel from a second fuel supply pipe at a mixing point to create a mixed fuel having a first calorie content. A control valve is located in the second fuel supply pipe upstream of the mixing point. A process system downstream of the mixing point processes the mixed fuel to create a processed mixed fuel having a second calorie content. A first control signal is reflective of the first calorie content of the mixed fuel. A second control signal is reflective of the second calorie content of the processed mixed fuel. A third control signal is reflective of the operating level of the combustion engine. A controller connected to the control valve operates the control valve based on the first, second, and third control signals. | 2010-12-02 |
20100304317 | CONTROL VALVES FOR HEATERS AND FIREPLACE DEVICES - In certain embodiments, a control valve assembly for gas heaters and gas fireplace devices includes a housing. The housing can define an inlet for accepting fuel from a fuel source, a first outlet for delivering fuel to an oxygen depletion sensor, and a second outlet for delivering fuel to a burner. The assembly can include a valve body configured to selectively provide fluid communication between the inlet and one or more of the first outlet and the second outlet, and can include an actuator configured to move the valve body relative to the housing. The actuator can be configured to transition between a resting state and a displaced state. The assembly can include an igniter that includes a sensor, the igniter electrically coupled with an electrode and configured to repeatedly activate the electrode when the sensor senses that the actuator is in the displaced state. The assembly can include a shutoff valve electrically coupled with the oxygen depletion sensor and configured to operate in response to an electrical quantity communicated by the oxygen depletion sensor. | 2010-12-02 |
20100304318 | FIRE AND WATER DISPLAY WITH INTEGRATED SAFETY FEATURES - A system for providing a combined water and fire display is provided. More specifically, a decorative display comprises a dynamic water and fire display device where fuel/air, water, and fire are integrated. The decorative display provides for unique aesthetic qualities and an appearance wherein flames are positioned at or near the surface of a volume of water. In various embodiments, the decorative display further comprises various safety features including the ability to detect and self-regulate conditions such as the existence and/or absence of a pilot flame, an adequate amount of water, and the temperature of various portions of the system. The decorative display further contemplates the ability to operate without one or more disclosed features, such as when only a water display or only a fire display is desired. | 2010-12-02 |
20100304319 | Label manufacturing method and label manufacturing apparatus - In order to suppress adhesion and accumulation of a heat sensitive adhesive onto a thermal head from a trailing end portion in a transporting direction of a heat sensitive adhesive sheet, to thereby enable smooth and continuous transporting of a plurality of the heat sensitive adhesive sheets, a thermal head and transporting means are driven so that a plurality of heating elements of the thermal head are selectively operated in synchronization with timing of transporting of a heat sensitive adhesive sheet ( | 2010-12-02 |
20100304320 | KILN - A kiln comprising a substantially cylindrical drum ( | 2010-12-02 |
20100304321 | FIVE SEGMENT ORTHODONTIC ARCH WIRE AND ORTHODONTIC APPARATUS MADE THEREOF - The present invention relates to an arch wire that is used during orthodontic treatment. In accordance to the present invention a five segment orthodontic arch wire to provide a track for movement of teeth for correcting misalignment of teeth, said arch wire generally having ‘U’ shape and having same longitudinal axis through out the length, said arch wire characterized by: first segment having rectangular cross section and being provided for the posterior, 2nd premolar and molar region in left side of the jaw; second segment having rectangular cross section with rounded off corners, said second segment is followed by said first segment and provided for the canine and first premolar region in left side of the jaw; third segment having rectangular cross section, said third segment is followed by said second segment and provided for the anterior, incisor region; fourth segment having rectangular cross section with rounded off corners, said fourth segment is followed by said third segment and provided for the canine and 1st premolar region in right side of the jaw; and fifth segment having rectangular cross section, said fifth segment is followed by said fourth segment and provided for the posterior, 2nd premolar and molar region in right side of the jaw, wherein said arch wire is single piece and continuous in construction. Also an orthodontic apparatus comprising a five segment orthodontic arch wire in accordance with the present invention along with slotted bracket is also provided. | 2010-12-02 |
20100304322 | Hand-held Device for Dispensing a Pasty Filling Material - A hand-held device, particularly for dental purposes, comprising a dispenser for dispensing a pasty filling material as well a device for emitting a radiation that causes the filling material to cure. | 2010-12-02 |
20100304323 | Dental Color Key - The invention relates to a dental color key comprising at least two different color patterns or samples with different tooth colors. The entire surface area of the color key ( | 2010-12-02 |
20100304324 | Dental unilateral bite block - A sheet of material having a central body portion with attached wings capable of folding towards each other on either side. The wings of the bite block fold toward each other along fold lines adjacent the central body portion and provide a structure for biting down upon for propping the mouth of a patient open during a dental procedure. A mirrored surface may be placed on the central body portion for improving visibility in the mouth. In a unilateral bite block embodiment, the unilateral bite block is placed in only one side of the mouth. The bite block may be made inexpensively and is disposable. | 2010-12-02 |
20100304325 | Elastically Deformable Bite Fork Stabilizer and Associated Methods - Methods and apparatus for stabilizing a bite fork in a patient's mouth. The apparatus may comprise an elastically deformable bite fork stabilizer. The elastically deformable bite fork stabilizer may comprise an elastically deformable layer, an adhesive layer on one side of the elastically deformable layer, and a removable layer adhered to the adhesive layer. | 2010-12-02 |
20100304326 | DEVICE AND METHOD FOR LOCATING A PULP CHAMBER IN A TOOTH - A pulp chamber locator assists a dentist in performing a root canal procedure. The device includes a generally circular plate and a plurality of struts extending from the plate. The plate has a hole in the vicinity of its center. The device is inserted over a tooth, such that the struts engage the cemento-enamel junction of the tooth. The hole then indicates the proper point of entry for a dental instrument. The device may also include a rotatable indicator for showing the proper angle of entry, to insure that the instrument reaches the pulp chamber of the tooth. The dentist adjusts the position of the indicator, based on information provided by an X-ray or equivalent, and positions the dental instrument so as to be generally parallel with the indicator. | 2010-12-02 |
20100304327 | INTERPROXIMAL TEETH CLEANING APPARATUS WITH AN AIR-DRIVEN SPRAY - Interproximal cleaning is produced by a combination of fluid droplets producing a certain impact shear stress on the interproximal biofilm combined with shear stress created by the effect of air driving a liquid film ( | 2010-12-02 |
20100304328 | TISSUE RETRACTOR - The invention relates to a tissue retractor ( | 2010-12-02 |
20100304329 | IMPLANT FIXTURE REMOVER - An implant fixture remover is provided which includes: a remover screw including a coupling screw portion screwed to a female screw portion of a fixture, and a separating screw portion formed to extend from one end of the coupling screw portion to the outside of the fixture and having a thread formed on the outer circumferential surface thereof; and a remover driver including a separating female screw portion into and to which the separating screw portion of the remover screw is inserted and screwed and in which a thread corresponding to the separating screw portion is formed in the inner circumferential surface thereof, a close coupling portion formed at the lower end of the separating female portion | 2010-12-02 |
20100304330 | TORQUE WRENCH, HANDLE AND HEAD PIECE - The present invention relates to a handle, a head piece and a wrench, such as a torque wrench, in particular for use in surgery and prosthetics, such as surgery and prosthetics within the dental field. A handle for a wrench is provided, wherein the handle comprises an elongated body element extending along a first axis, and a torque arm for indicating the torque applied to the torque arm, the torque arm having a proximal end attached to the body element. Furthermore, the handle comprises a first locking element, the first locking element being adapted to removably engage with a locking element of a head piece, and the handle further comprises a ratchet element that is adapted to engage with a tool piece in a ratchet gear. | 2010-12-02 |
20100304331 | Device for Positioning Artificial Teeth - The positioning device has two rows of seats, namely an upper row ( | 2010-12-02 |
20100304332 | DENTAL SUPERSTRUCTURE, AND A METHOD OF MANUFACTURE THEREOF - A dental superstructure with integrated spacers comprising a main body, wherein said superstructure is | 2010-12-02 |
20100304333 | EXPANDABLE DENTAL IMPLANT - An expandable dental implant is provided. The dental implant comprises a crown portion, an expandable root and a cam. The expandable root portion has a plurality of members pivotally coupled to the crown portion. The cam is coupled to the crown portion and is slidably engageable with at least a portion of the plurality of members to urge the members to pivot outward and expand the root portion. | 2010-12-02 |
20100304334 | Dental Implant System and Method of Use - A dental implant system includes an implant having a well and an abutment having a post shaped to be received in the tapered well. Both the implant and the abutment are made from a millable ceramic, and the abutment post and/or the implant well have grooves carved therein. In one embodiment, the implant and the abutment are joined one to the other with a retentive elastomeric product containing micro-bubbles and micro-spacers. The dental implant system may be produced using a computer-readable medium containing instructions for analyzing surface data and X-ray data, for developing contour data of the implant and of the abutment according to the anatomy of the patient, and for generating machine instruction for milling the implant and the abutment from blocks of the millable ceramic. The invention provides the dentist with total flexibility in determining the most appropriate contours of the implant system and in reducing inventory. | 2010-12-02 |
20100304335 | POST-EXTRACTION DENTAL IMPLANT - The invention relates to dental implants of the type used immediately after a tooth is extracted and intended to be placed in the alveolus after the extraction, the purpose of which is to increase both the long-term and the short-term stability of the implantation, and which basically comprises a conical body on which there is located a thread ( | 2010-12-02 |
20100304336 | THREADED CONNECTION WITH VARIABLE GAP - Threaded connection between a male part ( | 2010-12-02 |
20100304337 | LABORATORY IMPLANT - A method for the production of a dental implant with a post part which can be introduced into a jawbone and with a mounting part assigned thereto, on which a dental prosthetic piece can be mounted, is to allow the dental technician to perform a simple indexing of the mounting part while drawing on current procedural steps. For this purpose, the apical end of the mounting part is shaped in order to adapt the external cross-section of the mounting part to the internal cross-section of the post part. | 2010-12-02 |
20100304338 | POLYMER IMPRESSION MATERIALS - This invention relates to methods and compositions for single component photoinitiated dental impression materials. The impression material is workable in its pre-cured state, cures rapidly upon exposure to light, and exhibits desirable processing conditions such as short setting time, long working time, no void formation, good wettability, mechanical properties, and detail reproduction. | 2010-12-02 |
20100304339 | Method And Apparatus For Teaching Cosmetology - An apparatus and method is provided for teaching cosmetology. The apparatus includes a sensor and a computer-based controller. In operation, the sensor senses a cosmetology student performing a cosmetology operation and generates a sensor signal in response thereto. The controller processes the sensor signal and based thereon generates a control signal for displaying the cosmetology operation in a virtual manner on a video display. | 2010-12-02 |
20100304340 | Electromechanical Tactile Braille Cell Assembly - The present invention discloses an electromechanical tactile cell assembly comprising a plurality of piezoelectric element reeds, each one of the piezoelectric element reeds being bendable at an elongated end portion when a voltage is applied to the reed, a plurality of conductive fulcrum pins secured to a printed circuit board, and a plurality of multiple element conductive supports secured to a printed circuit board, each multiple element conductive support, in combination with the plurality of conductive fulcrum pins, adapted to secure a plurality of piezoelectric reeds, corresponding to the plurality of conductive fulcrum pins, to the printed circuit board. The electromechanical tactile cell is adaptable for use with a Braille display. | 2010-12-02 |
20100304341 | METHOD AND APPARATUS FOR GUIDING A CHILD IN THE SELF-SELECTION OF A NUTRITIONALLY-BALANCED MEAL IN ORDER TO INCREASE THE LIKELIHOOD THAT THE CHILD WILL CONSUME A NUTRITIONALLY-BALANCED MEAL - A method for guiding a child in the self-selection of a nutritionally-balanced meal in order to increase the likelihood that the child will consume a nutritionally-balanced meal, the method comprising:
| 2010-12-02 |
20100304342 | Interactive Language Education System and Method - An interactive system for improving conversational listening and speaking skills in a target language through interaction between personal communications devices (for example, mobile telephones using cellular or other wireless networks, telephones using PSTN lines, VOIP-enabled communications devices, smart phones, voice-enabled PDAs) and an automated system that provides oral/aural instruction and practice in vocabulary, pronunciation and grammar/syntax, engages the learner in simulated conversations, and provides personalized feedback and suggestions for further practice based on an analysis of the type and frequency of specific pronunciation and grammatical/syntactical errors. | 2010-12-02 |
20100304343 | Method and Apparatus for Language Instruction - A system is provided for acquiring increased proficiency in a new or target language by enabling frequent repeated hearing and mimicking of discrete audio sound bites in the target language, wherein the sound bites and their frequency of repetition may be easily selected by the user before or during use. The sound bites may be played singly or in sequential groups or user defined groups, and automatically repeated as necessary or desired to achieve audio imprinting of the sound bites by simply listening and repeating the sounds without substantial intellectual effort or attempts at memorization. The system enables user selected or sequential hearing and mimicking of specific sound bites or groups of sound bites repeatedly in each use session in the context of meaning, without requiring dedicated language learning time, and thereby helps reproduce the natural process of initial native language acquisition which occurs without substantial intellectual effort and memorization. | 2010-12-02 |
20100304344 | Overhead Door Forcible Entry Training Device - A forcible entry training device for use with overhead doors includes an adjustable frame that is designed to hold a variety of overhead doors of different sizes, and also includes an adjustable support that applies support from the back of the door and thereby provides structural integrity to the door so that multiple vertical cuts can be made through the door. In one embodiment, vertical members in the frame are adjustably connected to horizontal members. Clamps are provided in the vertical members to secure the edges of the overhead door to the frame. Adjustable-length stabilizing legs can be used to hold the frame and door in an upright position, even when resting on an uneven surface. | 2010-12-02 |
20100304345 | FIRE EXTINGUISHER TRAINING APPARATUS - Methods and apparatus for use in fire extinguisher training are provided. These methods and apparatus are implemented electronically without the need for an open flame. The training apparatus includes a display having a plurality of light sources adapted to display a varying light pattern simulating a dynamic flame; a sensor adapted to detect a stimulus emitted by one of a fire extinguisher and a fire extinguisher simulator and output a signal corresponding to the detected stimulus; and one or more processors adapted to receive the output from the sensor and vary the light pattern simulating the dynamic flame on the display in response to the stimulus detected by the sensor. The methods and apparatus may be used to train firefighters in the proper use of a fire extinguisher, for example, training in the techniques typically required when suppressing class A, B, C, D, and K type fires. | 2010-12-02 |
20100304346 | Training System for an Article of Footwear - A training system for an article of footwear is disclosed. The training system includes a method of training an athlete to use an article of footwear with a shape correcting member to perform various types of skills including passing a ball. The method can be implemented on a computer, mobile device or as an instruction booklet. The training system provides a total training solution for an athlete that is designed to enhance specific athletic skills. | 2010-12-02 |
20100304347 | Interactive Education System for Teaching Patient Care - An interactive education system for teaching patient care to a user is described. The system comprises a patient simulator; a virtual instrument for use with the patient simulator in performing patient care activities; means for sensing an interaction between the virtual instrument and the simulator, and means for providing feedback to the user regarding the interaction between the virtual instrument and the simulator. In one aspect, the system includes a maternal simulator, a fetal simulator, and a neonatal simulator. | 2010-12-02 |
20100304348 | EDUCATIONAL AND TRAINING TOOL USING MATCHING TECHNIQUES AND METHOD OF DEVELOPING AND UTILIZING THE SAME - A training and education tool in the form of a game. The game is facilitated by software and computer means. A personal computer, including a processor, display and interface device (e.g., mouse, touch screen, haptic device, etc.), is used to implement the education and training tool. A game creation tool allows a user to create a game matrix having game positions filled with text, symbols, colors and/or static or video images. Once the game is created, a game play tool utilizes recognition, association and repetition whereby a player must align two or more matching game matrix positions by switching the position of at least two game matrix positions within the game matrix. Each successful alignment results in an award of points and/or time. Difficulty increases as a player successfully advances through timed game levels. | 2010-12-02 |
20100304349 | INTERACTIVE MULTI-FUNCTIONAL GPS SYSTEM - In some embodiments, an interactive learning apparatus may include one or more of the following features: (a) a network disposed in a vehicle to enable communications between various devices in the vehicle, (b) a GPS device operably coupled to the network, (c) a computer operably coupled to the network wherein the computer is adapted to control execution of interactive learning program based upon input from the GPS device, (d) an existing vehicle electronics device for the purpose of supporting the interactive learning program, (e) a network interface coupled to the computer for interfacing with the network, (f) a user interface coupled to the network, (g) a memory for storing code executable by the computer, the code supporting play of one or more interactive GPS learning program, and (h) an interactive learning server coupled to the network for supporting play of one or more interactive learning programs. | 2010-12-02 |
20100304350 | FOLDABLE SUPPORT DEVICE FOR CAMERA OF HANDWRITING DEVICE AND HANDWRITING DEVICE HAVING SAME - A handwriting device includes a supporting device using two supporting arms with one end slidablely engaged in two respective sliding channel defined in a supporting base and the other end rotatably connected with each other for adjusting the height of a camera module supported by the supporting arms. | 2010-12-02 |
20100304351 | DISPLAY HAVING A 3D AESTHETIC COMPONENT ATTACHED THERETO - A showcasing system. The system includes a display board and a silhouetted 3D aesthetic component. The 3D aesthetic component includes (i) an unitary blank movable into a silhouetted 3D aesthetic surface, the 3D aesthetic component being attached to the display board and (ii) a plurality of die cutouts spaced along the longitudinal axis of the blank. | 2010-12-02 |
20100304352 | SYSTEMS AND METHODS FOR PRESERVING A HUMAN ORGAN FOR TRANSPLANTATION - A perfusion pump system for providing perfusate to an organ of a human body includes an actuator coupled to a pump to provide an actuating force to the pump. The pump includes an outlet for providing a perfusate to an organ coupled to the pump and an inlet for receiving the perfusate. The pump is configured to provide a pulsatile pumping force to the perfusate via a pumping stroke in response to the actuating force. The pumping stroke is followed by a return stroke. The pumping stroke causes the pump to collapse to force a flow of the perfusate through the outlet to the organ. The pump collapses in the direction of the flow of the perfusate. The return stroke allows the perfusate to enter the pump through the inlet and the return stroke of ways providing the perfusate through the outlet. | 2010-12-02 |
20100304353 | METHODS OF IMPROVING A GENOMIC MARKER INDEX OF DAIRY ANIMALS AND PRODUCTS - The present invention provides methods for improving desirable dairy traits through the use of a genomic marker index. Also provided are methods for determining an animal's genotype with respect to multiple markers used in calculation of the genomic marker index. The invention also provides methods for selecting or allocating animals for predetermined uses, for picking potential parent animals for breeding, and for producing improved dairy products. | 2010-12-02 |
20100304355 | DEVICES AND METHODS FOR PHARMACOKINETIC-BASED CELL CULTURE SYSTEM - Devices, in vitro cell cultures, systems, and methods are provided for microscale cell culture analogous (CCA) device. | 2010-12-02 |
20100304356 | ASSEMBLY AND A METHOD FOR IN SITU PROCESSING OF WASTE - The invention relates to a device and a method for the in situ processing of waste, in particular for cleaning up a waste disposal site. The device comprises a sorting device with a set of processing devices connected downstream of said device. This set of processing devices comprises a fermenting device, a fluidized bed gasifier, and a pyrolysis device. Furthermore, the assembly comprises a control device for controlling and measuring the various material flows. | 2010-12-02 |
20100304357 | UNIVERSAL DRINKING ADAPTER FOR BEVERAGE BOTTLES, AND DEVICES AND KITS FOR DETERMINING SMALL MOLECULES, METAL IONS, ENDOTOXINS, AND BACTERIA, AND METHODS OF USE THEREOF - Certain features, aspects, examples and embodiments described herein relate to adapters for securing drinking apparatuses for individuals of all ages (infants, children, adults, and seniors) such as nipples, sippers, and straws, to commercially available beverage containers to aid in the consumption of the contained liquid. Other features, aspects, examples and embodiments relate to devices and kits useful for the detection of analytes in milk samples such as small molecules, metal ions, endotoxins, and bacteria. | 2010-12-02 |
20100304358 | METHODS OF IDENTIFYING BIOLOGICAL TARGETS AND INSTRUMENTATION TO IDENTIFY BIOLOGICAL TARGETS - Methods of measuring and/or detecting biological targets, methods of distinguishing among the same type of biological target, single-molecule detection systems, fluorescent/biological target complexes, methods of using fluorescent/biological target complexes, and the like are disclosed. | 2010-12-02 |
20100304359 | MULTIANALYTE ASSAY - The invention provides compositions, systems and methods for detecting multiple analytes from a sample. | 2010-12-02 |
20100304360 | GOLD NANOPARTICLE HPV GENOTYPING SYSTEM AND ASSAY - The invention provides oligonucleotides, kits and methods for genotyping HPV. | 2010-12-02 |
20100304361 | METHOD AND DEVICE FOR MONITORING A THERAPEUTIC TREATMENT REGIME - A method for monitoring a therapeutic treatment regime in an individual having a disease, comprises: providing at a first location a solid substrate capable of immobilising a biomarker characteristic of the disease and a therapeutic compound in the biological sample, contacting the biological sample with the solid substrate to immobilise the biomarker and the therapeutic compound; transferring the solid substrate with the immobilised biomarker and therapeutic compound to a second location; performing an extraction step on the solid substrate to extract the biomarker and the therapeutic compound; performing a first detection assay to detect and/or quantify the biomarker, performing a second detection assay to quantify the therapeutic compound; and correlating the detection and/or quantity of the biomarker with the disease state of the individual, and comparing the quantity of the therapeutic compound with a target level for treatment of the disease, thereby to assess the efficacy of the treatment regime. | 2010-12-02 |
20100304362 | NEW DETECTION METHOD FOR CERVICAL HPVS - The invention describes a consensus PCR based method (i.e. HRE7-PCR) for the simultaneous detection of 14 Human Papilloma Virus types (i.e. HPV 16, 18, 31, 33, 35, 39, 45, 51, 52, 56, 58, 59, 66, and 68) that are classified as (probably) high-risk, relating to the causation of cervical cancer) and a candidate hrHPV type (i.e. HPV 67) using sets of 6 overlapping forward primers and 9 overlapping backward primers that together amplify a fragment of about (215) to (245) base pairs of the E7 open reading frame of these hrHPV types. For the detection of reaction products an EIA format can be used with the aid of a cocktail of type-specific oligoprobes as exemplified herein. Furthermore, we have developed a method for an efficient typing of these (15) HPVs that is compatible with the method for detection. This RLB typing system involves hybridisation of PCR products with immobilised type-specific oligoprobes. | 2010-12-02 |
20100304363 | PEPTIDE COMPOUNDS FOR DETECTING OR INHIBITING SARS CORONAVIRUS AND APPLICATION THEREOF - Disclosed herein are peptide compounds and the application thereof to the detection and inhibition of SARS coronavirus. Composed of dipeptides, the compounds for detecting and inhibiting SARS coronavirus can be readily synthesized and produced at low cost. In addition, they can be stored safely for a long period of time. The dipeptide compounds are useful as inhibitors of SARS coronavirus as well as acting as excellent capturing materials of SARS coronavirus. | 2010-12-02 |
20100304364 | Compositions and methods for monosynaptic transport - Disclosed herein are methods of expressing a heterologous nucleic acid sequence, such as a sequence encoding a detectable protein, in a primary neuron (or plurality of primary neurons) and other neurons that are monosynaptically connected to the primary neuron (or plurality of primary neurons). Such methods involve viruses (such as, rabies viruses) defective for transsynaptic transport (TST-defective virus) and in situ complementation of the defect in a manner that permits only monosynaptic transport of the TST-defective virus. The TST-defective virus and, therefore, any heterologous nucleic acid sequence it carries in its genome, are not transmitted to neurons that are not monosynaptically connected to the primary neuron (or plurality of primary neurons). Also disclosed are methods of targeting a TST-defective virus to a genetically defined primary neuron (or plurality of primary neurons). The disclosed technology enables far more specific labelling and/or manipulation of neural networks than has previously been possible. | 2010-12-02 |
20100304365 | MUTATION OF PRPS1 GENE CAUSING CMTX5 DISEASE AND THE USE THEREOF - Disclosed is a gene mutation associated with peripheral neuropathy associated with sensorineural hearing loss and optic neuropathy. More specifically, disclosed are: a polynucleotide comprising a mutation associated with peripheral neuropathy associated with sensorineural hearing loss and optic neuropathy, or a complementary polynucleotide thereof; a polynucleotide which hybridizes with said polynucleotide; a polypeptide which is encoded by said polynucleotide; an antibody which binds to said polypeptide; and a microarray chip and a kit, which comprise said polynucleotide. Also disclosed are a method for diagnosing a syndrome of peripheral neuropathy associated with sensorineural hearing loss and optic neuropathy, a method for detecting the mutation, and a method for screening drugs for treating these diseases. | 2010-12-02 |
20100304366 | Methods for Determining Virulence and Invasiveness Among Various Staphylococcus Aureus Strains - This invention describes quick diagnostic methods to distinguish CA-MRSA MW2 or CA-MRSA USA300 strains in clinical samples from various sources. Fluorescent labeled primers which amplify 1) two unique agr sequences from each strain, 2) a partial spa gene and 3) a partial pvl gene are packaged into a multiplex PCR kit. A real-time instrumentation to amplify and quantify the PCR amplification products, measured by the change of each of the labeled fluorescent reporter and their thermal melting curve, provides a simple and rapid identification of the most virulent and invasive MRSA strains in the United States. | 2010-12-02 |
20100304367 | COMPOSITIONS FOR REAL-TIME, SINGLE MOLECULE SEQUENCE DETERMINATION - A sequencing methodology is disclosed that allows a single DNA or RNA molecule or portion thereof to be sequenced directly and in substantially real time. The methodology involves engineering a polymerase and/or dNTPs with atomic and/or molecular tags that have a detectable property that is monitored by a detection system. | 2010-12-02 |
20100304368 | COMPONENTS AND METHOD FOR ENZYMATIC SYNTHESIS OF NUCLEIC ACIDS - Novel methods for enzymatic synthesis of nucleic acid chains and the substrates for the same are disclosed. The methods are based on a step-wise enzymatic reaction. The sequencing of nucleic acids is an example of the use of the claimed methods. | 2010-12-02 |
20100304369 | METHOD AND APPARATUS FOR DIAGNOSING AGE-RELATED MACULAR DEGENERATION - Disclosed is a method for identifying an individual who has an altered risk for developing age-related macular degeneration comprising detecting an insertion/deletion polymorphism in the ARMS2 gene | 2010-12-02 |
20100304370 | INTRACELLULAR PH SENSOR USING NUCLEIC ACID ASSEMBLIES - Disclosed are nucleic acid-based sensors for measuring the pH of a sample, including cells, regions thereof, and whole organisms. The sensor includes an I-switch that is triggered by protons, and which functions as a FRET-based pH sensor inside living cells and organisms. Also disclosed are compositions and methods for measuring the pH of a specific region of a cell, such as vesicles, the nucleus, mitochondrial matrix, or the Golgi lumen. | 2010-12-02 |
20100304371 | COMPOSITIONS AND METHODS FOR DETECTING MYCOBACTERIA - The present invention features compositions and methods that can be used to analyze samples for the presence of | 2010-12-02 |
20100304372 | Liver Cancer Methods and Compositions - The present invention provides a novel method for detection of liver cancer. This method detects high-sensitively, high-specifically, simply and accurately liver cancer, especially that in early stage by identifying and/or quantifying methylation on particular genes and/or their DNA fragments in clinical specimens, and by combining said methylated DNA values with existing tumor marker values and/or DNA amounts in blood. This invention also detects a precancerous lesion, detects a risk of recurrence after treatment of liver cancer, detects malignancy of liver cancer and monitors progression of liver cancer with time by the same method. As for particular genes, BASP1 gene, SPINT2 gene, APC gene, CCND2 gene, CFTR gene, RASSF1 gene and SRD5A2 gene are mentioned. | 2010-12-02 |
20100304373 | Methods for Assessing the Susceptibility of a Human to Diminished Health and Wellness - The present invention relates to methods for assessing the advisability that a human should employ a compensatory composition comprised of one or more antioxidant ingredients. The methods involve assessing occurrence in the human's genome of a plurality of certain polymorphisms. Methods for determining the composition of preferred compensatory compositions are also disclosed. | 2010-12-02 |
20100304374 | METHODS AND TOOLS FOR DISCRIMINATING COLORECTAL ADENOMAS AND ADENOCARCINOMAS - The present invention relates to the differential expression of genes in colorectal adenoma and adenocarcinoma cells and their correlation with chromosomal aberrations. The present invention provides tools for detecting chromosomal aberrations linked to progression of adenomas into adenocarcinoma cells. The present invention discloses methods and tools for in vivo and in vitro diagnosis of colorectal tumours. | 2010-12-02 |
20100304375 | Influenza Virus Genome Replication and Transcription System in Yeast Cells - A system in which vRNP purified from influenza virus particles is introduced into yeast ( | 2010-12-02 |
20100304376 | Epigenetic Silencing of Cyclooxygenase-2 Affects Clinical Outcome in Gastric Cancer - The present invention discloses methods of using the methylation status of the COX-2 gene promoter region as a biomarker for a gastric cancer patient to determine a prognosis and a treatment regimen, and to monitor the progress of a treatment regimen. | 2010-12-02 |
20100304377 | METHOD OF DETECTING NOROVIRUS RNA - The amount of an RNA transcription product amplified in an RNA amplification process is measured using a nucleic acid probe labeled with an intercalating fluorescent dye. The RNA amplification process comprises the steps of using at least two sets of primer pairs comprising a first primer and a second primer (in which one of these primers carries a promoter sequence added to the 5′ end thereof), both of which have high hybridization efficiency to a nucleic acid sequence that is homologous to or complementary to each norovirus genotype RNA; forming a double-stranded DNA containing the promoter sequence with a reverse transcriptase; forming an RNA transcription product with an RNA polymerase by using the double-stranded DNA as a template; and forming the double-stranded DNA by successively using the RNA transcription product as a template in the DNA synthesis with the reverse transcriptase. | 2010-12-02 |
20100304378 | Method for Detecting or Quantifying a Truncating Mutation - The present invention discloses a new method for detecting or quantifying a truncating mutation of a target gene in a subject, said method relying on the in vitro compartmentalization of single genetic constructs in aqueous droplets of a water-in-oil emulsion. | 2010-12-02 |
20100304379 | SPORES FOR THE STABILIZATION AND ON-SITE APPLICATION OF BACTERIAL WHOLE-CELL BIOSENSING SYSTEMS - The presently-disclosed subject matter is directed to biosensors comprising spore-forming bacterial cells and/or spores generated therefrom, a recognition unit within each spore-forming cell for binding an analyte of interest, and a reporter molecule within each spore-forming cell for detecting binding of the analyte of interest, wherein the reporter molecule generates a detectable signal upon binding of the analyte by the recognition element. The presently-disclosed subject matter further provides methods of using the biosensors and systems and kits including the biosensors. | 2010-12-02 |
20100304380 | Quantitative DNA Methylation Imaging of Cells and Tissues - The invention is a method using immunofluorescence, high-resolution imaging, and 3D image analysis to quantify spatial distribution of methylcytosine (MeC) in global DNA in individual cell nuclei, for the characterization of cells and tissues based on their nuclear MeC distribution patterns. The invented method is intended for basic research, clinical diagnostics and prognostics, pharmacology and toxicology, and molecular and cell-based therapy. | 2010-12-02 |
20100304381 | FLUORESCENT NUCLEOBASE CONJUGATES HAVING ANIONIC LINKERS - Provided are nucleotide-dye conjugates and related compounds in which a dye is linked to a nucleobase directly or indirectly by an anionic linker. The anionic character of the linker is provided by one or more anionic moieties which are present in the linker, such as phosphate, phosphonate, sulfonate, and carboxylate groups. When the dye is a provided as a donor/acceptor dye pair, the anionic linker can be located between the donor and the acceptor, or between the nucleobase and either the donor or acceptor, or both. In one embodiment, conjugates of the invention provide enhanced electrophoretic mobility characteristics to sequencing fragments, e.g., for dideoxy sequencing using labeled terminators. | 2010-12-02 |
20100304382 | Gene Defects and Mutant ALK Kinase in Human Solid Tumors - In accordance with the invention, novel gene deletions and translocations involving chromosome 2 resulting in fusion proteins combining part of Anaplastic Lymphoma Kinase (ALK) kinase with part of a secondary protein have now been identified in human solid tumors, e.g. non-small cell lung carcinoma (NSCLC). Secondary proteins include Echinoderm Microtubule-Associated Protein-Like 4 (EML-4) and TRK-Fusion Gene (TFG). The EML4-ALK fusion protein, which retains ALK tyrosine kinase activity, was confirmed to drive the proliferation and survival of NSCLC characterized by this mutation. The invention therefore provides, in part, isolated polynucleotides and vectors encoding the disclosed mutant ALK kinase polypeptides, probes for detecting it, isolated mutant polypeptides, recombinant polypeptides, and reagents for detecting the fusion and truncated polypeptides. The disclosed identification of this new fusion protein enables new methods for determining the presence of these mutant ALK kinase polypeptides in a biological sample, methods for screening for compounds that inhibit the proteins, and methods for inhibiting the progression of a cancer characterized by the mutant polynucleotides or polypeptides, which are also provided by the invention. | 2010-12-02 |
20100304383 | BIOMARKERS FOR PRENATAL DIAGNOSIS OF CONGENITAL CYTOMEGALOVIRUS - The invention provides compositions and methods useful for early detection of congenital CMV infection, predicting the likelihood and severity of congenital CMV disease, and monitoring the efficacy of therapeutic approaches. Compositions of the present invention include biomarkers that are differentially expressed in CMV-infected mothers and fetuses compared to uninfected individuals. | 2010-12-02 |
20100304384 | METHOD OF IDENTIFYING COMPOUNDS THAT INDUCE OR INHIBIT ENDOPLASMIC RETICULUM STRESS OR OXIDATIVE STRESS - The present invention generally relates to a method for the identification of compounds for the treatment of neurodegenerative diseases. Said method is based on a cell model for neurodegeneration useful for the identification of potentially useful compounds for the treatment or the prevention of a neurodegenerative disease associated with deficient expression of the DDIT3 gene, also known as CHOP. | 2010-12-02 |
20100304385 | ASSAY - The invention provides a LAMP assay for detection of meningococcal disease, the test comprising at least one nucleic acid primer set capable of detecting | 2010-12-02 |
20100304386 | ENZYMES FOR AMPLIFICATION AND COPYING BISULPHITE MODIFIED NUCLEIC ACIDS - The invention relates to the use of enzymes for copying or amplifying bisulphite modified or treated nucleic acids, wherein the enzymes are more effective in copying or amplifying the nucleic acid compared with native Taq polymerase under substantially the same conditions. | 2010-12-02 |
20100304387 | METHODS AND COMPOSITIONS FOR SIGNAL ENHANCEMENT USING MULTIVALENT INTERACTIONS - Methods and materials are disclosed relating to an improved method for amplifying a signal in a diagnostic assay for an analyte, using an amplification polymer that multivalently binds to one or more non-analyte-specific binding site of the multivalent bridge conjugate, if present on the solid support. | 2010-12-02 |
20100304388 | Biomarker For Successful Aging Without Cognitive Decline - Methods and compositions for determining whether a subject will age without developing cognitive decline are provided. An exemplary method includes detecting one or more allelic variants in a gene encoding low density lipoprotein-related protein 1B. In a preferred embodiment, the detecting step is accomplished by contacting a sample obtained from the subject with a probe that forms a detectable complex with a nucleic acid in the sample containing an allelic variant indicative of aging without developing cognitive decline, wherein detection of the allelic variant in the sample indicates that the subject will age without developing cognitive decline. | 2010-12-02 |
20100304389 | Preparation And Isolation of 5' Capped mRNA - The synthesis of capped/tagged RNA, methods of use and kits providing same are contemplated. Tagged RNA permits isolation of RNA transcripts in vitro. The ability to isolate and purify capped RNA results in improved transcription and translation and provides a tool for identifying RNA-protein interactions. Such capped RNA finds use in therapeutic applications, diagnosis and prognosis and in the treatment of cancers and HIV. | 2010-12-02 |
20100304390 | METHODS FOR DETECTING GENE DYSREGULATIONS - Described herein are methods, compositions and kits directed to the detection of gene dysregulations such as those arising from gene fusions and/or chromosomal abnormalities, e.g. translocations, insertions, inversions and deletions. Samples containing dysregulated gene(s) of interest may show independent expression patterns for the 5′ and 3′ regions of the gene. The methods, compositions and kits are useful for detecting mutations that cause the differential expression of a 5′ portion of a target gene relative to the 3′ region of the target gene. | 2010-12-02 |
20100304391 | METHODS FOR ASSESSMENT AND TREATMENT OF DEPRESSION VIA UTILIZATION OF SINGLE NUCLEOTIDE POLYMORPHISMS ANALYSIS - Described herein are assays, kits and methods for treating depression, including the diagnosis and treatment of depression based on the determination of genetic predispositions towards inhibition or enhancement of Ca2+/calmodulin-dependent protein kinase II (CaMKII). For example, described herein are methods and kits (including assays) for determining if one or more gene in an excitatory or inhibitory pathway for modulating CaMKII activity or expression is likely to be inhibited or enhanced by an SNP. Also described are methods and kits (including assays) for prescribing treatment based on the identification of SNPs that may modulate CaMKII. | 2010-12-02 |
20100304392 | HEPATITIS B VIRAL VARIANTS WITH REDUCED SUSCEPTIBILITY TO NUCLEOSIDE ANALOGS AND USES THEREOF - The present invention relates generally to viral variants exhibiting reduced sensitivity to particular agents and/or reduced interactivity with immunological reagents. More particularly, the present invention is directed to hepatitis B virus (HBV) variants exhibiting complete or partial resistance to nucleoside or nucleotide analogs and/or reduced interactivity with antibodies to viral surface components including reduced sensitivity to these antibodies. The present invention further contemplates assays for detecting such viral variants, which assays are useful in monitoring anti-viral therapeutic regimens and in developing new or modified vaccines directed against viral agents and in particular HBV variants. The present invention also contemplates the use of the viral variants to screen for and/or develop or design agents capable of inhibiting infection, replication and/or release of the virus. | 2010-12-02 |
20100304393 | Genetic predictors of international normalized ratio (INR) fluctuation with warfarin therapy - There are disclosed methods and kits for identifying a subject having genetic predictors of predisposition to abnormal international normalized ratio (INR) fluctuation during warfarin therapy. In an embodiment, a method includes testing the subject to check for a presence of a predetermined genetic variation. The predetermined genetic variation is correlated with abnormal INR fluctuation during warfarin therapy. The subject is identified as having a predisposition to abnormal INR fluctuation during warfarin therapy when the testing indicates the presence of the predetermined genetic variation. In one embodiment, a kit includes a test to check the subject for a presence of a predetermined genetic variation. The predetermined genetic variation is correlated with abnormal INR fluctuation during warfarin therapy. The kit includes an indicator to identify the presence of the predetermined genetic variation so as to identify the subject as having a predisposition to abnormal INR fluctuation during warfarin therapy. | 2010-12-02 |
20100304394 | Screening methods involving the detection of short-lived proteins - A method is provided for screening for agents that affect protein degradation rates, the method comprising: taking a library of cells, the cells expressing a fusion protein comprising a reporter protein and a protein encoded by a sequence from a cDNA library derived from a sample of cells, the sequence from the cDNA library varying within the cell library; contacting the library of cells with a plurality of agents which may affect protein degradation rates; for each agent, selecting cells in the library which express short-lived proteins based on whether the cells have different reporter signal intensities than other cells in the library, the difference being indicative of the selected cells expressing shorter lived fusion proteins than the fusion proteins expressed by the other cells in the library; and characterizing the fusion proteins expressed by the selected cells for each agent. | 2010-12-02 |
20100304395 | Method, Program, and System for Normalizing Gene Expression Amounts - The present invention aims at presenting novel means for analyzing and correcting gene expression amounts. There is provided a gene expression amount normalizing method in which the number of cells in a sample is obtained by measuring a repeated sequence present in a substantially fixed proportion in a genome contained in the sample, and the number of cells obtained is used as an index for normalizing gene expression amounts obtained from the same sample. For example, a DNA sample | 2010-12-02 |
20100304396 | ANIMAL HEALTH DIAGNOSTICS - A physical blood sample of animal is sent to a satellite laboratory facility. The blood sample is pre-processed into sub-samples of the sample and the sub-samples are coded. The coded blood sub-samples are physically carried to the main laboratory for analysis. The satellite facility electronically inputs a request for a laboratory analysis by a main laboratory. The request is electronically transmitted to the main laboratory, and the main laboratory coordinates the electronically received input from the satellite facility with the physical blood sub-samples. A computer report of the analysis from the laboratory is obtained for the satellite facility. A clinical pathologist with data of physical characteristics of the animal makes a diagnosis. A menu on a computer permits the generation of a supplemental report to support the diagnosis. An integrated computer report having the laboratory analysis, supplemental report, and a pathologist-enhanced report is electronically communicated to the client. | 2010-12-02 |
20100304397 | Chromogenic test kit for detecting health conditions in saliva - A device and method for detecting diseases, disorders and health conditions in saliva or other body fluid. The method employs solid phase immunoassay and similar detecting processes along with one of several bioluminescent reactions such that the presence of specific biomarkers is reported visually on a chromogenic panel incorporated directly into the test kit. The device does not require electricity or refrigeration, and results in a small, sealed diagnostic packet that can be safely discarded or stored as necessary. | 2010-12-02 |
20100304398 | NOVEL DIAGNOSTIC SENSOR FOR RAPID AND REPRODUCIBLE RO52 PROTEIN DOMAIN DETECTION - The present invention relates to the use of specific synthetic sensor molecules for the discrimination of proteins and protein domains involved in autoimmunity. More specifically, in one embodiment, the invention relates to the detection of antibodies which bind to specific domains of the Ro52 protein. In another embodiment, the invention relates to the use of specific synthetic sensor molecules to identify domains of the Ro52 protein with different antibody specificities. The invention also includes a method for assessing the risk that a fetus will develop congenital heart block. The invention enables the evaluation and differential diagnosis of a range of autoimmune disorders, allowing appropriate treatment or more generally medical intervention decisions to be made. | 2010-12-02 |