46th week of 2010 patent applcation highlights part 49 |
Patent application number | Title | Published |
20100292486 | RECYCLABLE METATHESIS CATALYSTS - Highly active, recoverable and recyclable transition metal-based metathesis catalysts and their organometallic complexes including dendrimeric complexes are disclosed, including a Ru complex bearing a 1,3-dimesityl-4,5-dihydroimidazol-2-ylidene and styrenyl ether ligand. The heterocyclic ligand significantly enhances the catalytic activity, and the styrenyl ether allows for the easy recovery of the Ru complex. Derivatized catalysts capable of being immobilized on substrate surfaces are also disclosed. The present catalysts can be used to catalyze ring-closing metathesis (RCM), ring-opening (ROM) and cross metatheses (CM) reactions, and promote the efficient formation of various trisubstituted olefins at ambient temperature in high yield. | 2010-11-18 |
20100292487 | CHEMICAL PROCESS FOR THE PREPARATION OF BENZOXAZOLE DERIVATIVES USED AS PESTICIDES - This invention relates to a process for the preparation of compounds of formula (I): where R | 2010-11-18 |
20100292488 | ORGANIC DYES AND PHOTOELECTRIC CONVERSION DEVICES - Organic dyes and photoelectric conversion devices are provided. The Organic dye has the structure represented by formula (I), wherein, n is an integral of 2-11; the plurality of X is independent and elected from the group consisting of | 2010-11-18 |
20100292489 | Cross-conjugated 2,5-cyclohexadienone and related synthesis methods - The present invention relates to methods for the synthesis of galanthamine, morphine, intermediates, salts and derivatives thereof. In preferred embodiments, the invention relates to methods for improving the efficiency and overall yield of said morphine, morphine related derivatives and intermediates thereof. In further embodiments, the invention relates to methods for improving the efficiency and overall yield of galanthamine and intermediates thereof. | 2010-11-18 |
20100292490 | A PROCESS FOR PRODUCING GAMMA MANGOSTIN - A process for the production of γ-mangostin comprising the steps of preparing O-methyl γ-mangostin preferably from plants, subjecting the pure or partially pure O-methylated γ-mangostin to demethylation reaction procedure followed by purification of the said demethylated product to obtain pure γ-mangostin. | 2010-11-18 |
20100292491 | Method of Making Ketals and Acetals - The reaction of alcohols with oxocarboxylates to form acetals or ketals is catalyzed by unexpectedly low levels of protic acids. By employing low acid catalyst levels compared to amounts conventionally used, rapid formation of acetal or ketal is facilitated while the formation of oxocarboxylate esters is minimized. Further employing a significant molar excess of oxocarboxylate in conjunction with low acid catalyst level gives rise to the rapid and clean formation of acetals and ketals from oxocarboxylates and alcohols. | 2010-11-18 |
20100292492 | CATALYSTS FOR ESTERIFICATION OF EPOXIDIZED SOYATES AND METHODS OF USING SAME - A combination of catalysts is disclosed as useful to promote the transesterification reaction of an epoxidized soyate with a polyol to yield a high percentage of epoxidized soyate diester with epoxy functionality retained. The primary catalyst is a metallic hydroxide, and the secondary catalyst is a titanate. Bioderived plasticizers useful for thermoplastics and thermosets result. | 2010-11-18 |
20100292493 | DECANTATION IMPROVEMENT IN A METHOD OF PRODUCING ALKYL ESTERS FROM VEGETABLE OR ANIMAL OIL AND AN ALIPHATIC MONOALCOHOL - The present invention describes a method of producing fatty acid alkyl esters and glycerin implementing, in a reaction section, a set of transesterification reactions between a vegetable or animal oil and an aliphatic monoalcohol, and using a heterogeneous solid catalyst, comprising:
| 2010-11-18 |
20100292494 | A METHOD FOR TREATING A MIXTURE CONTAINING AN ESTER COMPOUND, A CHEMICAL PROCESSING EQUIPMENT, A MIXTURE CONTAINING AN ESTER COMPOUND, AND A COMPOSITION OF ESTER COMPOUNDS - The invention relates to a method of treating a mixture ( | 2010-11-18 |
20100292495 | METHOD FOR THE RECOMBINANT PRODUCTION OF MAGNETIC NANOPARTICLES - The present invention relates to methods and compositions for the size-adjusted recombinant production of magnetic nanoparticles. More particular, the invention relates to a method, comprising: providing one or more cells being capable of producing magnetic nanoparticles; modifying in the one or more cells the expression of one or more genes involved in the formation of the magnetic nanoparticles; cultivating the modified cells obtained in step (b); and isolating the magnetic nanoparticles from the cultivated cells, wherein the magnetic nanoparticles have a defined size. In preferred embodiments, the method comprises modifying the expression of one or more genes of the mamGFDC operon in magnetotactic bacterial cells. The invention is further directed to host cells bearing said modifications, the recombinant magnetic particles isolated from such cells as well as to the use of such particles for the detection and/or separation of biomolecules or as a contrast agent in magnetic resonance imaging. | 2010-11-18 |
20100292496 | Process for Production of Alkyl Tin Alkoxide Compound, and Process for Production of Carbonic Acid Ester Using the Compound - The present invention provides a process for producing: a compound represented by XOR | 2010-11-18 |
20100292497 | POLYCARBONATE DIOL WITH EASE OF REACTION STABILIZATION - A polycarbonate diol comprising repeating units represented by the following formula (A) and a terminal hydroxy group. It is characterized in that 60-100 mol % of the repeating units represented by the formula (A) are repeating units represented by the following formula (B) or (C), the amount of the repeating units represented by the formula (B) is 10-50 mol %, excluding 50 mol %, based on the total amount of the repeating units represented by the formula (A), and the polycarbonate diol has a terminal primary OH ratio of 95-98.5%. (A) (In the formula, R represents a C | 2010-11-18 |
20100292498 | Site-Specific Inhibitors of Histone Methyltransferase [HMTASE] and Process of Preparation Thereof - The present invention relates to compounds of structural formula (I) as site-specific inhibitor of histone methyl-transferase, where R | 2010-11-18 |
20100292499 | SHORTENED SYNTHESIS USING PARAFORMALDEHYDE OR TRIOXANE - The present disclosure relates to a process for the preparation of a compound of formula (I) wherein R is hydrogen, a formyl group, a straight, branched or cyclic C | 2010-11-18 |
20100292500 | NPY Y5 ANTAGONIST - The present invention provides a pharmaceutical composition for use as art NPY Y5 receptor antagonist comprising a compound or the formula (I): | 2010-11-18 |
20100292501 | PROCESS FOR RECOVERING SULFONIC ACID CATALYST AND NOBLE PRODUCTS FROM ACRYLATE HEAVY ENDS - Sulfonic acid catalyst, e.g., methanesulfonic acid (MSA), and noble products, e.g., acrylic acid, butanol and butyl acrylatε, are recovered from acrylate reactor blowdown. The blowndown comprises, among oilier things, the Michael ad ducts of the sulfonic acid and acrylate esters. The blowdown is mixed with water, subjected to conditions sufficient to crack or hydrolyze the Michael addνcts into their constituent parts. These cracking conditions are also sufficient to allow the recovery of the sulfonic acid and constituent parts, as well as other light components of the heavy ends, e.g., unreacted acrylic acid and butanol, | 2010-11-18 |
20100292502 | Method for preparing high-purity fesoterodine fumarate - A process is described for preparing fesoterodine fumarate comprising the salification reaction of fesoterodine with fumaric acid in an organic solvent, preferably a ketone, at a temperature not greater than 45° C. Such process allows obtaining products with high yields and purities, and in particular a product having a content of (2E)-4-[(3-(3-diisopropylamino-1-phenylpropyl)-4-(2-isobutyroyloxyphenyl)methoxy]-4-oxobut-2-enoic acid less than or equal to 0.15% by mole. | 2010-11-18 |
20100292503 | Method for preparing fesoterodine and/or fesoterodine fumarate - A process is described for preparing fesoterodine and/or fesoterodine fumarate comprising the esterification of (R)-feso deacyl with isobutyric acid or a precursor thereof, such as an isobutyryl halide or the isobutyric acid anhydride to give fesoterodine, in a mixture of water at alkaline pH and/or at least one organic solvent. This process allows obtaining products with high yields and purities, and in particular a product having a content of (R)-2-[3-(diisopropylamino)-1-phenylpropyl]-4-isobutyroyloxymethyl-phenyl isobutyrate less than 1% by mole and a content of (R)-2-[3-(diisopropylamino)-1-phenylpropyl]-4-(hydroxymethyl)phenol less than 0.05% by mole. | 2010-11-18 |
20100292504 | BORON-CONTAINING SMALL MOLECULES - This invention provides, among other things, novel compounds useful for treating bacterial infections, pharmaceutical compositions containing such compounds, as well as combinations of these compounds with at least one additional therapeutically effective agent. | 2010-11-18 |
20100292505 | Sulfanyl Derivatives And Their Use As Synthesis Intermediates - The present application relates to sulfanyl derivatives of formula (I) and to their use as synthesis intermediates, especially for the preparation of the pharmaceutically active compound mesna. Formula (I), wherein X is O or N—C(NH)NH | 2010-11-18 |
20100292506 | PROCESS FOR THE SYNTHESIS OF PREGABALIN - A process for the preparation of a compound of formula (I) is disclosed, | 2010-11-18 |
20100292507 | PROCESS FOR CONVERTING LEVULINIC ACID INTO PENTANOIC ACIDITLE - A process for converting levulinic acid into pentanoic acid, comprising the following steps: (a) supplying hydrogen and a feedstock comprising levulinic acid to a first catalytic zone comprising a strongly acidic catalyst and a hydrogenation metal; (b) converting, in the first catalytic zone, the levulinic acid at a temperature in the range of from 100 to 250° C. into gamma valerolactone to obtain a first effluent comprising gamma valerolactone; (c) supplying at least part of the first effluent to a second catalytic zone comprising a strongly acidic catalyst and a hydrogenation metal; and (d) converting, in the second catalytic zone, gamma valerolactone into pentanoic acid at a temperature in the range of from 200 to 350° C. to obtain a second effluent comprising pentanoic acid, wherein the conversion temperature in the first catalytic zone is lower than the conversion temperature in the second catalytic zone, and wherein the acidic catalyst and the hydrogenation metal in the first catalytic zone has the same composition as the acidic catalyst and the hydrogenation metal in the second catalytic zone. | 2010-11-18 |
20100292508 | SURFACE MODIFIED HEXAGONAL BORON NITRIDE PARTICLES - Provided is a composition comprising hexagonal boron nitride particles having a surface and a substituted phenyl radical bonded to the surface, the substituted phenyl radical being represented by the structure: | 2010-11-18 |
20100292509 | VEGFC PRODUCTION PROMOTER - A bloating ameliorant, a lymphatic vessel activator and a VEGFC production promoter comprising a tranexamic acid amide derivative and/or salt thereof. | 2010-11-18 |
20100292510 | PROCESS FOR PREPARING CYCLOALIPHATIC AMINES - A process for preparing cycloaliphatic amines by hydrogenating the corresponding aromatic compounds with hydrogen-comprising gas at a temperature of from 30 to 280° C. and a pressure of 50-350 bar, in the presence of ruthenium catalysts. The hydrogenation is performed in the presence of from 1% by weight to 500% by weight, based on the catalyst calculated as elemental ruthenium (Ru), of suspended inorganic additives, and to the use of the cycloaliphatic amines as a synthesis unit. | 2010-11-18 |
20100292511 | PURIFICATION OF IMPURE HEXAMETHYLENEDIAMINES - Impure hexamethylenediamines and more particularly those hexamethylenediamines containing contaminating amounts of tetrahydroazepine (THA), or more generally contaminating amounts of imines, are purified by distillation carried out with a short retention time of the impure hexamethylenediamine in the distillation column; the hexamethylenediamine obtained has a very low concentration of THA. | 2010-11-18 |
20100292512 | Methylated Curcumin-Resveratrol Hybrid Molecules for Treating Cancer - Methylated curcumin-methoxystilbene hybrid molecules that have particular use in treating cancer. | 2010-11-18 |
20100292513 | PROCESS FOR PRODUCTION OF BENZALDEHYDE COMPOUND - A benzaldehyde acetal compound of formula (3): | 2010-11-18 |
20100292514 | Hydroformylation process - A process for the production of 4-hydroxybutyraldehyde is described. The process comprises reacting allyl alcohol with a mixture of carbon monoxide and hydrogen in the presence of a solvent and a catalyst comprising a rhodium complex and a diphosphine. The diphoshine is a trans-1,2 -bis(bis(3,4-di-n-alkylphenyl)phosphinomethyl)cyclobutane and/or a 2,3-O-isopropylidene- | 2010-11-18 |
20100292515 | Purification method of high-molecular-weight polyethylene glycol compound - An impurity derived from a high-molecular-weight polyethylene glycol compound is removed from a high-molecular-weight polyethylene glycol compound whose total average number of moles of ethylene oxide units added in the molecule is 220 to 4500. In a state where the high-molecular-weight polyethylene glycol compound is dissolved in at least one of water and an organic solvent selected from aromatic hydrocarbon solvents having 8 or less carbon atoms in total and ester compound solvents having 5 or less carbon atoms in total, the water and the organic solvent are mixed. The resulting mixture was separated into an organic layer and an aqueous layer, and the organic layer is separated from the aqueous layer. | 2010-11-18 |
20100292516 | Process for Producing Perfluoroalkyne Compound - A process for producing a perfluoroalkyne compound includes an addition reaction step of adding Cl | 2010-11-18 |
20100292517 | PRODUCTION OF VAPOUR-CRACKING LOADS WITH A HIGH YIELD OF THE RESULTING ETHYLENE, PROPYLENE AND POLYMERS BY HYDROPROCESSING OF VEGETABLE OILS - The invention describes a process for treatment of a feedstock that is obtained from a renewable source that comprises a hydrotreatment stage in the presence of at least one fixed-bed catalyst, whereby said catalyst comprises a hydro-dehydrogenating function and an amorphous substrate, at a temperature of between 50 and 450° C., at a pressure of between 1 MPa and 10 MPa, at an hourly volumetric flow rate of between 0.1 h−1 and 10 h−1, and in the presence of a total quantity of hydrogen that is mixed with the feedstock such that the hydrogen/feedstock ratio is between 50 and 1000 Nm3 of hydrogen/m3 of feedstock, followed by a separation from the hydrotreated effluent that is obtained from stage a) of hydrogen, gases, and at least one liquid hydrocarbon effluent that consists of at least 50% linear n-paraffins, and a steam-cracking of at least one portion of the liquid hydrocarbon effluent that is obtained from stage b). | 2010-11-18 |
20100292518 | TWO-STEP HYDROTREATMENT OF A FEED DERIVED FROM A RENEWABLE SOURCE USING A FIRST, METALLIC, CATALYST AND A SECOND, SULPHURIZED, CATALYST - The invention describes a two-step process for hydrotreatment of a feed derived from a renewable source, comprising:
| 2010-11-18 |
20100292519 | AROMATIC ALKYLATION PROCESS WITH REDUCED BYPRODUCT FORMATION - Byproduct formation in aromatic alkylation processes is reduced when different polyalkylated aromatic compounds are first fractionated into separate streams enriched in these respective polyalkylated aromatic compounds, and the separate streams are sent to different transalkylation reaction zones, which may or may not be in the same reactor. The different transalkylation reaction zones allow for greater control of the transalkylation of the respective polyalkylated aromatic compounds, such as diisopropylbenzene (DIPB) and triisopropylbenzene (TIPB) that accompany the alkylation of benzene with propylene in a process for cumene production. | 2010-11-18 |
20100292520 | PROCESS FOR PRODUCING ALKENES OXYGENATES BY USING SUPPORTED HETEROPOLYACID CATALYSTS - The present invention relates to a supported heteropolyacid catalyst, to a process for producing alkenes from oxygenates in the presence of said catalyst, and to the use of said catalyst in a process for producing alkenes from oxygenates at a higher productivity whilst reducing the formation of alkanes. | 2010-11-18 |
20100292521 | SEPARATING OLEFIN STREAMS - This invention pertains to separating an olefin stream into at least two olefin streams. The olefin stream that is to be separated is low in diene composition, which allows the olefin stream to be compressed at a relatively high temperature without causing fouling problems in the compressor system. The invention is particularly relevant to separating olefins obtained from an oxygen to olefins unit. | 2010-11-18 |
20100292522 | Stabilized Ceramic Composition, Apparatus and Methods of Using the Same - In one aspect, the invention includes a refractory material, said material comprising: (i) at least 20 wt. % of a first grain mode stabilized zirconia based upon the total weight of said material, said first grain mode having a D50 grain size in the range of from 5 to 2000 μm, said stabilized zirconia including a matrix oxide stabilizer; (ii) at least 1 wt. % of a second grain mode having a D50 grain size in the range of from 0.01 μm up to not greater than one-fourth the D50 grain size of said first grain mode zirconia, based upon the total weight of said material; and (iii) at least 1 wt. % of a preservative component within at least one of said first grain mode stabilized zirconia, said second grain mode stabilized zirconia, and an optional another grain mode; wherein after sintering, said material has porosity at 20° C. in the range of from 5 to 45 vol %. | 2010-11-18 |
20100292523 | Pyrolysis Reactor Materials and Methods - In one aspect, the invention includes a reactor apparatus for pyrolyzing a hydrocarbon feedstock, the apparatus including: a reactor component comprising a refractory material in oxide form, the refractory material having a melting point of at least 2060° C. and which remains in oxide form when exposed to a gas having an oxygen partial pressure of 10 | 2010-11-18 |
20100292524 | METHANE RECOVERY FROM A LANDFILL GAS - A process is provided for recovering methane from landfill feed gas and other anaerobic digestors. The process comprising the following steps: firstly treating the feed gas to remove H | 2010-11-18 |
20100292525 | Method of processing waste material - An aspect of the present invention is a method of processing a waste material that contains mercury or a mercury compound, and chlorine or a mercury chloride, the method including a step of adding a chlorine scavenger to the waste material, and stowing the waste material in a treatment vessel; and a step of subjecting the waste material to a blasting treatment by fitting an explosive to the treatment vessel and detonating the explosive inside a pressure-proof container. | 2010-11-18 |
20100292526 | BRACHYTHERAPY APPLIANCE AND METHOD - A brachytherapy appliance removably positionable on or against a surface of a living body, such as the body of a human or animal, for positioning a therapeutic delivery device in a desired precise location in relation to a selected portion of the body in or adjacent to the surface and containing a cancer, tumor, or other diseased tissue, for delivering a therapy, particularly radiation, to the diseased tissue, and a method of making the appliance so as to conform to the body surface, based on a computerized three dimensional model or map generated from a scan of the body region, the appliance being particularly adapted for use in a body cavity such as the oral cavity. | 2010-11-18 |
20100292527 | DEVICE AND METHOD FOR HYPERTENSION TREATMENT BY NON-INVASIVE STIMULATION TO VASCULAR BARORECEPTORS - The treatment of hypertension may be accomplished by stimulation of the carotid baroreceptors. In the present application the inventors disclose methods in which non-invasively-delivered mechanical perturbations caused by sound, ultrasound, or electrical perturbations caused by magnetic, or direct current stimulation may be used to stimulate the carotid baroreceptors, triggering physiological responses that treat medical disorders including hypertension. | 2010-11-18 |
20100292528 | Wrap for a Heart Assist Device - A heart assist device in which an inflatable balloon or chamber is held against an outside surface of a curved arterial vessel by a wrap ( | 2010-11-18 |
20100292529 | BONE ANCHORED BONE CONDUCTIVE HEARING AID - The invention relates to a bone anchored bone conductive hearing aid which has a bone implantable screw ( | 2010-11-18 |
20100292530 | METHOD AND APPARATUS FOR FIXATION OF IMPLANTABLE DEVICES ADJACENT A BODY LUMEN - The present application relates to method and apparatus for reducing migration and rotation of implantable devices including an expandable element and an elongate portion. | 2010-11-18 |
20100292532 | Endoscopic Vessel Dissector With Side Entry - A blunt dissector for endoscopic vein harvesting has a generally-cylindrical sheath for retaining an elongated endoscope. The sheath is elongated between a distal end and a proximal end. A transparent tip is disposed at the distal end of the sheath. A handle is disposed at the proximal end of the sheath. The sheath includes a selectably closable longitudinal slot having an opened configuration such that the endoscope can be inserted radially into the sheath. The longitudinal slot has a closed configuration that retains the endoscope within the sheath and presents a substantially smooth outer surface for use during dissection. | 2010-11-18 |
20100292533 | Endoscopic Cutter with Reconfigurable Guides - A bipolar cutter has a cutter main body for inserting into the interior of a body and a treating electrode that is positioned against an object of examination (such as a blood vessel or a bleeding site) to be electrically cut and cauterized. A guiding member guides the object of examination toward the treating electrode as it is displaced in the axial direction of the cutter main body. The guiding member is comprised of a pair of protruding members and a notched groove or gap that leads to the treating electrode while in a first configuration. A gap adjusting mechanism causes the guiding member or the treating electrode to be displaced in the axial direction to reduce or eliminate the length of the gap so that the treating electrode can better reach flat tissue surfaces for treatment. | 2010-11-18 |
20100292534 | BODY-INTRODUCABLE APPARATUS AND MEDICAL SYSTEM - A body-introducable apparatus includes: a light source unit having a first light source that outputs first light and a second light source that outputs second light in a wavelength band different from that of the first light; a light distribution matching unit that matches distributions of the first light and the second light; an illuminating control unit that illuminates the inside of the subject by driving the light source unit; and an imaging unit that captures an image of the inside of the subject. | 2010-11-18 |
20100292535 | Endoscope with multiple fields of view - An endoscope having first and second viewing elements provides separate views of the passage being traversed or the organ being inspected. The endoscope is particularly useful for traversing restrictions and forming desired shapes in situ. | 2010-11-18 |
20100292536 | FLUID CONTROL DEVICE AND FLUID CONTROL METHOD, AND ENDOSCOPE APPARATUS - A fluid control device which controls a flow rate of a fluid supplied or sucked to or from an inflation and deflation member, includes: a first pipe system connected to the inflation and deflation member, wherein the fluid flow of a predetermined flow rate is supplied to the first pipe system; a second pipe system connected to the inflation and deflation member, wherein a fluid flow of a flow rate lower than the predetermined flow rate is supplied to the second pipe system; a device which switches the first pipe system to the second pipe system when a predetermined amount of fluid is supplied or sucked to or from the inflation and deflation member through the first pipe system; and a device which controls the pressure in the inflation and deflation device by using the second pipe system based on a pressure in the second pipe system. | 2010-11-18 |
20100292537 | INNER PRESSURE DETECTION DEVICE AND INNER PRESSURE DETECTION METHOD FOR INFLATION AND DEFLATION MEMBER, AND ENDOSCOPE APPARATUS - An inner pressure detection device for an inflation and deflation member includes: a pressure detection device which detects a pressure of a fluid at a first position in a proximal end side of a tube for supplying a fluid to an inflation and deflation member and exhausting a fluid from the inflation and deflation member, the inflation and deflation member included in an insertion portion configured to be inserted in a body cavity; a pressure loss calculation device which calculates a pressure loss of the fluid in the tube between the first position and a position in a distal end side of the tube where the inflation and deflation member is provided; and an inner pressure calculation device which calculates an inner pressure of the inflation and deflation member based on the pressure loss calculated by the pressure loss calculation device and the pressure detected by the pressure detection device. | 2010-11-18 |
20100292538 | ENDOSCOPE - A front end rigid portion constitutes a front end of an endoscope insertion unit in an endoscope. The front end rigid portion is provided with an illumination optical system irradiating an observation target area with illumination light and an imaging optical system having an imaging element imaging the observation target area. The endoscope includes a heat emission member which is connected to the front end rigid portion and extends in the longitudinal direction of the endoscope insertion unit. The heat emission member is formed by mixing fiber-piece-shaped fillers with a resin material. | 2010-11-18 |
20100292539 | Forward Scanning OCT Endoscope - An apparatus for optical coherence tomography has a broadband light source with a short coherence length, an optical fiber that guides the light from the light source to a focusing optics, and a graded-index optics arranged between the optical fiber and the focusing optics with two opposite parallel flat sides, that is contacted on its first flat side by the optical fiber forming an irradiation point guiding light to the graded-index optics and having a pitch of N/8, N being a natural number that cannot be divided by 4. A first structure for light reflection is arranged on the first flat side of the graded-index optics adjacent to the irradiation point, and a second structure for beam splitting is arranged on the second flat side of the graded-index optics. The focusing optics are designed for focusing the light transmitted by the second structure essentially at right angles to the flat sides of the graded-index optics. | 2010-11-18 |
20100292540 | SURGICAL RETRACTOR AND METHOD - A retractor instrument for use in surgery having a body section and attachment tabs for securing the retractor to tissue. The retractor may have multiple body sections joined by hinges or ribs and may be rigid or flexible or some combination thereof. The retractor may comprise bioabsorbable material as well as hemostatic material. The retractor is suitable for use with clips, staples, sutures and tacks. | 2010-11-18 |
20100292541 | SYSTEMS, DEVICES AND METHODS FOR ACCESSING A BODILY OPENING - Medical systems, devices and methods are provided for accessing a bodily opening that, among other things, are safe and reliable, and facilitate manipulation of a medical instrument. The medical access device generally includes an elongated flexible sheath and an expandable frame connected to the distal end of the flexible sheath. The sheath and expandable frame are operable between expanded and collapsed configurations to provide a pathway from a natural orifice to the bodily opening. | 2010-11-18 |
20100292542 | ARM STRUCTURE AND HOLDING DEVICE FOR SURGICAL INSTRUMENT - An arm structure includes: a pair of arms; a support post; a support member; a cam provided in one of the pair of arms; a shaft member inserted through a lateral insertion hole of the support member; and a pair of ring-shaped members provided in end portions of the shaft member, wherein by turning the one of the arms around its axis thereby to make the cam revolve, a force works to make the shaft member move, and due to its reaction force the ring-shaped members pressure-contact the support member and a slit portion is narrowed. As a result, a longitudinal insertion hole is diameter-reduced and becomes in a state of pressure-contacting the support post, leading to restriction of rotation of the arm around the support post, and the cam pressure contacts the one of the arms, leading to restriction of sliding of the arm in a long side direction, and the ring-shaped members pressure-contact the support member, leading to restriction of rotation of the arm by the shaft member. | 2010-11-18 |
20100292543 | Analysis of Endogenous Fluorescence Images to Extract Morphological/Organization Information About Living Samples - Methods and computer program products for analyzing tissue are provided. The tissue is exposed to light at the appropriate wavelengths for inducing fluorescence. Images of the fluorescing tissue are taken at two or more depths within the tissue. The PSD function is determined for each image at a different depth within the tissue. A characteristic of each PSD function determined is compared, and it is determined whether or not the tissue exhibits a pre-cancerous characteristic. | 2010-11-18 |
20100292544 | LIFE SUPPORT AND MONITORING APPARATUS WITH MALFUNCTION CORRECTION GUIDANCE - A life support and monitoring apparatus with malfunction correction guidance is provided. The life support and monitoring apparatus of the present disclosure identifies the root cause or potential cause of a fault/failure and then prompts an operator to take appropriate steps to assure the continuance of life support and critical physiologic monitoring. When multiple faults/failures exist, the apparatus automatically prioritizes them based on risk to the patient and prompts the operator to do the most appropriate intervention to assure patient safety. | 2010-11-18 |
20100292545 | INTERACTIVE PSYCHOPHYSIOLOGICAL PROFILER METHOD AND SYSTEM - An efficient, objective, flexible and easily deployable system for conducting evaluations of mental and physiological state and recommending individualized treatment to improve said state is described. The method and system are based on commensurate measurement of mental functions, levels of stress and anxiety, and/or biologically active molecules such as neurotransmitters, immune markers including cytokines and hormones. The method and system are designed to assess an individual's cognitive function and the underlying physiology in order to delineate various disease processes, injuries, drug states, training stages, fatigue levels, stress levels, aging processes, predict susceptibility to stress and/or sleep deprivation, identify aptitude for training and/or characterize effects of any experimental conditions. The system and method may be used in recommending individualized treatment protocols, as well as to guide the treatment process by assessing the efficacy of such therapies in the clinical trials process. | 2010-11-18 |
20100292546 | BREATHABLE PHYSIOLOGICAL SENSOR - A sensor includes a sensor pad that allows air and moisture to diffuse from a patient's skin. A light source is disposed on the sensor pad is configured to generate near-infrared light. A light detector disposed on the sensor pad is configured to detect near-infrared light generated by the light source. | 2010-11-18 |
20100292547 | SYSTEM AND METHOD FOR NON-INVASIVE PHOTOTHERMAL RADIOMETRIC MEASUREMENT - There is provided a glucose monitoring method and apparatus based on the principle of Wavelength-Modulated Differential Laser Photothermal Radiometry (WM-DPTR). Two intensity modulated laser beams operating in tandem at specific mid-infrared (IR) wavelengths and current-modulated synchronously by two electrical waveforms 180 degrees out-of-phase, are used to interrogate the tissue surface. The laser wavelengths are selected to absorb in the mid infrared range (8.5-10.5 μm) where the glucose spectrum exhibits a discrete absorption band. The differential thermal-wave signal generated by the tissue sample through modulated absorption between two specific wavelengths within the band (for example, the peak at 9.6 and the nearest baseline at 10.5 μm) lead to minute changes in sample temperature and to non-equilibrium blackbody radiation emission. This modulated emission is measured with a broadband infrared detector. The detector is coupled to a lock-in amplifier for signal demodulation. Any glucose concentration increases will be registered as differential photothermal signals above the fully suppressed signal baseline due to increased absorption at the probed peak or near-peak of the band at 9.6 μm at the selected wavelength modulation frequency. The emphasis is on the ability to monitor blood glucose levels in diabetic patients in a non-invasive, non-contacting manner with differential signal generation methods for real-time baseline corrections, a crucial feature toward precise and universal calibration (independent of person-to-person contact, skin, temperature or IR-emission variations) in order to offer accurate absolute glucose concentration readings. | 2010-11-18 |
20100292548 | Method And Apparatus For Detecting And Analyzing Variations In A Physiologic Parameter - The present disclosure is generally directed to identifying and/or analyzing high resolution variations in a measured physiologic parameter, such as blood oxygen saturation (SpO | 2010-11-18 |
20100292549 | METHOD AND SYSTEM FOR MONITORING OXYGENATION LEVELS OF COMPARTMENTS AND TISSUE - A method and system for continually monitoring oxygenation levels in real-time in compartments of an animal limb, such as in a human leg or a human thigh or a forearm, can be used to assist in the diagnosis of a compartment syndrome. The method and system can include one or more near infrared compartment sensors in which each sensor can be provided with a compartment alignment mechanism and a central scan depth marker so that each sensor may be precisely positioned over a compartment of a living organism. The method and system may comprise hardware or software (or both) may adjust one or more algorithms based on whether tissue being monitored was traumatized or is healthy. The method and system can also monitor the relationship between blood pressure and oxygenation levels and activate alarms based on predetermined conditions relating to the oxygenation levels or blood pressure or both. | 2010-11-18 |
20100292550 | IMPLANTABLE MEDICAL DEVICE - An analyte measuring system has an implantable medical device having a signal source arranged for generating a current signal and electrodes for applying the current signal to a surrounding tissue in a subject body. The device measures a resulting voltage signal with the electrodes and calculates an impedance signal therefrom. The system comprises a signal processor arranged for generating an estimate of a concentration of an analyte in the tissue based on a spectrum analysis of the determined impedance signal. | 2010-11-18 |
20100292551 | Devices, systems, methods and tools for continuous glucose monitoring - One aspect of the invention provides a glucose monitor having a plurality of tissue piercing elements, each tissue piercing element having a distal opening, a proximal opening and interior space extending between the distal and proximal openings; a sensing area in fluid communication with the proximal openings of the tissue piercing elements; sensing fluid extending from the sensing area into substantially the entire interior space of the tissue piercing elements; and a glucose sensor adapted to detect a concentration of glucose in the sensing fluid within the sensing area. Another aspect of the invention provides a method of in vivo monitoring of an individual's interstitial fluid glucose concentration including the following steps: inserting distal ends of a plurality of tissue piercing elements through a stratum corneum area of the individual's skin, the tissue piercing elements each having a distal opening, a proximal opening, an interior space extending between the distal and proximal openings, and a sensing fluid filling substantially the entire interior space; and sensing a glucose concentration of the sensing fluid. | 2010-11-18 |
20100292552 | Analyte Monitoring Device and Methods of Use - An analyte monitor includes a sensor, a sensor control unit, and a display unit. The sensor has, for example, a substrate, a recessed channel formed in the substrate, and conductive material disposed in the recessed channel to form a working electrode. The sensor control unit typically has a housing adapted for placement on skin and is adapted to receive a portion of an electrochemical sensor. The sensor control unit also includes two or more conductive contacts disposed on the housing and configured for coupling to two or more contact pads on the sensor. A transmitter is disposed in the housing and coupled to the plurality of conductive contacts for transmitting data obtained using the sensor. The display unit has a receiver for receiving data transmitted by the transmitter of the sensor control unit and a display coupled to the receiver for displaying an indication of a level of an analyte. The analyte monitor may also be part of a drug delivery system to alter the level of the analyte based on the data obtained using the sensor. | 2010-11-18 |
20100292553 | Analyte Monitoring Device and Methods of Use - An analyte monitor includes a sensor, a sensor control unit, and a display unit. The sensor has, for example, a substrate, a recessed channel formed in the substrate, and conductive material disposed in the recessed channel to form a working electrode. The sensor control unit typically has a housing adapted for placement on skin and is adapted to receive a portion of an electrochemical sensor. The sensor control unit also includes two or more conductive contacts disposed on the housing and configured for coupling to two or more contact pads on the sensor. A transmitter is disposed in the housing and coupled to the plurality of conductive contacts for transmitting data obtained using the sensor. The display unit has a receiver for receiving data transmitted by the transmitter of the sensor control unit and a display coupled to the receiver for displaying an indication of a level of an analyte. The analyte monitor may also be part of a drug delivery system to alter the level of the analyte based on the data obtained using the sensor. | 2010-11-18 |
20100292554 | Analyte Monitoring Device and Methods of Use - An analyte monitor includes a sensor, a sensor control unit, and a display unit. The sensor has, for example, a substrate, a recessed channel formed in the substrate, and conductive material disposed in the recessed channel to form a working electrode. The sensor control unit typically has a housing adapted for placement on skin and is adapted to receive a portion of an electrochemical sensor. The sensor control unit also includes two or more conductive contacts disposed on the housing and configured for coupling to two or more contact pads on the sensor. A transmitter is disposed in the housing and coupled to the plurality of conductive contacts for transmitting data obtained using the sensor. The display unit has a receiver for receiving data transmitted by the transmitter of the sensor control unit and a display coupled to the receiver for displaying an indication of a level of an analyte. The analyte monitor may also be part of a drug delivery system to alter the level of the analyte based on the data obtained using the sensor. | 2010-11-18 |
20100292555 | Analyte Monitoring Device and Methods of Use - An analyte monitor includes a sensor, a sensor control unit, and a display unit. The sensor has, for example, a substrate, a recessed channel formed in the substrate, and conductive material disposed in the recessed channel to form a working electrode. The sensor control unit typically has a housing adapted for placement on skin and is adapted to receive a portion of an electrochemical sensor. The sensor control unit also includes two or more conductive contacts disposed on the housing and configured for coupling to two or more contact pads on the sensor. A transmitter is disposed in the housing and coupled to the plurality of conductive contacts for transmitting data obtained using the sensor. The display unit has a receiver for receiving data transmitted by the transmitter of the sensor control unit and a display coupled to the receiver for displaying an indication of a level of an analyte. The analyte monitor may also be part of a drug delivery system to alter the level of the analyte based on the data obtained using the sensor. | 2010-11-18 |
20100292556 | METHODS AND SYSTEMS FOR MANAGING, CONTROLLING AND MONITORING MEDICAL DEVICES VIA ONE OR MORE SOFTWARE APPLICATIONS FUNCTIONING IN A SECURE ENVIRONMENT - Systems and methods that include configurations of a medical device, user device and service platform are described. Embodiments may include a secure network to run medical applications that control and/or monitor the medical device. An online store may be provided for storing and distributing medical applications to the user device and medical device. A secure environment may be provided within the user device and medical device that protects the integrity of medical applications running on those devices. A service platform may provide a service that enables a medical authority to certify and monitor the medical applications. In some implementations, various third parties and the user of the user device may be allowed to manage and monitor the medical device. | 2010-11-18 |
20100292557 | METHOD AND DEVICE FOR SUBSTANCE MEASUREMENT - Embodiments of the present disclosure present systems, devices and methods for ISF glucose monitoring that more accurately reflects the blood glucose levels by introducing a treatment element allowing stable and accurate prediction of blood glucose levels based measured glucose levels from interstitial fluid. | 2010-11-18 |
20100292558 | IN-VIVO VISUALIZATION SYSTEMS - In vivo visualization systems are described which facilitate tissue treatment by a user in utilizing real time visualized tissue images with generated three-dimensional models of the tissue region of interest, such as the left atrial chamber of a subject's heart. Directional indicators on the visualized tissue as well as the imaging systems may be utilized while other variations may utilize image rotation or manipulation of visualized tissue regions to facilitate catheter control. Moreover, visualized tissue regions may be combined with imaged tissue regions as well as navigational information to further facilitate tissue treatments. | 2010-11-18 |
20100292559 | RADAR-EQUIPPED PATIENT BED FOR A MEDICAL IMAGING APPARATUS, AND OPERATING METHOD THEREFOR - A patient bed for an imaging medical apparatus has a patient support plate that has at least one radar antenna to obtain physiological and/or geometric data from a patient the patient support plate. In a method for the operation of such a patient bed having at least one radar antenna in an imaging medical apparatus, the at least one radar antenna is operated to obtain data from the patient on the patient support plate. | 2010-11-18 |
20100292560 | Diffusion Tensor Imaging-Based Alzheimer's Diagnosis System and Method - A system and method is provided in which a diffusion tensor image of the gray matter of a subject's brain is recorded. The diffusion tensor image is used to determine the Fractional Anisotropy of that area of the subject's brain. It has been determined that a decrease in Fractional Anisotropy is related to a decrease in dendritic quality and/or quantity in the subject's brain, which is typically caused by the presence of Alzheimer's Disease. Consequently, the Fractional Anisotropy determination is used to diagnosis the presence of Alzheimer's Disease. | 2010-11-18 |
20100292561 | METHOD AND APPARATUS TO DETERMINE A MAGNETIC RESONANCE RELAXATION TIME IN THE HEART MUSCLE IN A MAGNETIC RESONANCE EXAMINATION - In a method and magnetic resonance (MR) system to determine an MR relaxation time (for example a T | 2010-11-18 |
20100292562 | Method for generating MR (Magnetic resonance) images of a moving partial area of an object - A method for generating MR (magnetic resonance) images of a moving partial area of an object with a repeating motion sequence over comparable motion states, wherein an MR data set, which is encoded for generating an individual MR image of the object, is provided for each motion state from a plurality of successive individual MR measurements with shorter time intervals than a repetition rate of the motion sequence, and wherein at least one navigator data point is generated for each individual MR measurement as an indicator for the comparability of several motion states, is characterized in that a position of the partial area is determined for each individual MR image, from which a function f(t) of the time shift of the position is determined, and the measuring data of the individual MR measurement is phase-corrected in correspondence with its respective motion state using the function f(t) to keep the position of the partial area in a spatially stationary state. This permits observation of a moving partial area irrespective of its motion state, such that rapid changes within the partial area can be observed. | 2010-11-18 |
20100292563 | Optical MRI device - A dual modality imaging apparatus, comprising a magnetic resonance imaging (=MRI) system and a fluorescence molecular tomography (=FMT) system, for investigating a sample ( | 2010-11-18 |
20100292564 | System and Method For Magnetic-Nanoparticle, Hyperthermia Cancer Therapy - A system and method is provided for performing and monitoring a magnetic nanoparticle hyperthermia process on a subject having received a dose of a magnetic nanoparticle configured to bind to tissue within a target area of the subject. A low-field MRI system is utilized having a static magnetic field and a radio frequency (RF) system configured to receive MRI data from the target area. A hyperthermia system is coupled to the low-field MRI system and configured to generate a hyperthermia excitation field configured to cause the magnetic nanoparticle to rotate at a lag with respect to a magnetic field experienced by the magnetic nanoparticle to cause a temperature increase in the target area. The MRI system is configured to acquire medical imaging data from the target area and reconstruct images therefrom indicating at least one of a spatial distribution of the nanoparticle in and a temperature of the target area. | 2010-11-18 |
20100292565 | MEDICAL IMAGING MEDICAL DEVICE NAVIGATION FROM AT LEAST TWO 2D PROJECTIONS FROM DIFFERENT ANGLES - In a method or system for performing an image-assisted medical procedure involving placing a medical device in a 3D human subject, at least first and second 2D projected images are obtained of the 3D subject at a respective first angle and at a respective second angle, the 3D subject having at least one of the points selected from the group consisting of a start point and an end point for guidance of the medical device. At least one of the start point and the end point are identified in each of the first and second 2D images. 3D positions of at least one of the start point and the end point are calculated. At least one of these start and end point 3D positions are overlaid as a back-projection to a live 2D image. The procedure is performed utilizing the live 2D image with at least one of the start and end points as a guide to place the medical device. The medical device may comprise, for example, a wire or a needle. | 2010-11-18 |
20100292566 | LOAD DETECTION DEVICE AND LOAD DETECTION METHOD - According to this load detection method, load (Fi) in insertion of a linear body having flexibility in an inlet of a hollow tube inserted in a bending vessel in a body is detected, an image of the hollow tube or the linear body is taken, a degree of bending of the hollow tube or the linear body is detected based on the image, and load (Fo) at a tip end of the linear body is calculated based on the detected insertion load (Fi) and the degree of bending. Therefore, the load (Fo) at the tip end of the thin linear body can readily be detected. | 2010-11-18 |
20100292567 | Imaging Volumes with Arbitrary Geometries in Contact and Non-Contact Tomography - A method for tomographic imaging of diffuse medium includes directing waves into a diffusive medium, solving a surface-bounded inversion problem by forward field calculations through decomposition of contributions from the multiple reflections from an arbitrary surface within the diffusive medium or outside the diffusive medium into a sum of different orders of reflection up to an arbitrary order, and using contact or non-contact measurements of waves outside said diffusive medium to generate a tomographic image. | 2010-11-18 |
20100292568 | SYSTEMS AND METHODS FOR MEASUREMENT OF DEPTH OF BREATH AND PARADOXICAL BREATHING - A radar-based physiological motion sensor is disclosed. Doppler-shifted signals can be extracted from the signals received by the sensor. The Doppler-shifted signals can be digitized and processed subsequently to extract information related to the cardiopulmonary motion in one or more subjects. The information can include respiratory rates, heart rates, waveforms due to respiratory and cardiac activity, direction of arrival, abnormal or paradoxical breathing, etc. In various embodiments, the extracted information can be displayed on a display. | 2010-11-18 |
20100292569 | SYSTEMS AND METHODS FOR DYNAMIC IMAGING OF TISSUE USING DIGITAL OPTICAL TOMOGRAPHY - A methods for imaging tissue using diffuse optical tomography with digital detection includes directing at the tissue a plurality of amplitude modulated optical signals from a plurality of optical signal sources illuminating the tissue at a plurality of locations; detecting a resulting plurality of attenuated optical signals exiting the tissue to obtain a plurality of analog signals containing diffuse optical tomographic information; converting the analog signals into digital signals; recovering the tomographic information from the digital signals using a digital signal processor-based detection module that performs digital detection, wherein the detection module includes a master digital signal processing subsystem and at least one slave digital signal processing subsystem that processes at least a portion of the digital signals and the master digital signal processing subsystem controls the at least one slave digital signal processing subsystem; and transmitting the recovered tomographic information in digital form to a host computer. | 2010-11-18 |
20100292570 | MEDICAL IMAGING APPARATUS AND MEDICAL IMAGING METHOD - An injection part injects a contrast agent into a subject. An image acquiring part images the subject with the contrast agent injected, and acquires a plurality of image data with different imaging times. A pixel value calculator obtains a pixel value within a region of interest set in each of the image data acquired by the image acquiring part, for each of the image data. An injection controller controls injection of the contrast agent by the injection part in accordance with the pixel value obtained for each of the image data. | 2010-11-18 |
20100292571 | NODULE SCREENING USING ULTRASOUND ELASTOGRAPHY - A medical device is configured to diagnose whether a nodule of a bodily organ is malignant or benign using ultrasound elastography to determine a nodule stiffness index. Using either an external compression source or an in vivo pulsation source, the stiffness of the nodule of the bodily organ can be quantified by either its static properties or dynamic properties. The nodule can be classified as Type I, which is benign requiring further observation, or Type II, which is malignant requiring invasive procedures. | 2010-11-18 |
20100292572 | METHOD AND SYSTEM OF STRAIN GAIN COMPENSATION IN ELASTICITY IMAGING - A method and system of strain gain compensation in elasticity imaging is provided. The system can include a probe ( | 2010-11-18 |
20100292573 | ULTRASOUND OPERATION APPARATUS, CAVITATION CONTROL METHOD, AND ULTRASOUND TRANSDUCER CONTROL METHOD - An ultrasound operation apparatus comprises: an ultrasound transducer; a driving section that drives the ultrasound transducer by a drive signal; a probe having a proximal end section provided with the ultrasound transducer and a distal end section to which ultrasound oscillation is transmitted, the probe performing a treatment on a living tissue using ultrasound oscillation at the distal end section; a detecting section that detects, from a drive signal, a physical quantity which varies due to cavitation generated by ultrasound oscillation of the distal end section; and an output control section that controls an output of the driving section in accordance with the detected physical quantity. | 2010-11-18 |
20100292574 | Ultrasound diagnostic system and method for displaying organ - Disclosed is an ultrasound diagnostic system and method. The ultrasound diagnostic system may receive, from a target object, a response signal corresponding to an ultrasound signal transmitted to the target object, may generate an ultrasound image and at least one organ image by using ultrasound data generated based on the received response signal, and may display the generated ultrasound image and the generated at least one organ image. | 2010-11-18 |
20100292575 | DEVICE AND METHOD FOR IDENTIFYING TAMPERING OF AN ULTRASOUND PROBE - An ultrasound probe includes a housing having an interior chamber formed therein. The ultrasound probe also includes an electronics assembly provided in the housing, the electronics assembly converting acoustic energy to electrical signals, and a tamper indicating substance applied to the ultrasound probe, the tamper indicating substance adapted to provide a visual indication when the ultrasound probe has been tampered with. A system including the ultrasound probe and a method of fabricating the ultrasound probe are also provided. | 2010-11-18 |
20100292576 | DEVICE FOR IMPROVED EXTERNAL FETAL MONITORING - The present invention described herein is a soft, pliable, cushioning device to be used in conjunction with ultrasound and toco transducers during external fetal monitoring. The device can be shaped to fit the transducers and can easily attach and detach with the transducers via an adhesive layer. The device provides comfort to the patient and improved continuity of the transducers' readings during external fetal monitoring. The device can be a single-use application or reusable. | 2010-11-18 |
20100292577 | ULTRASOUND IMAGE DIAGNOSIS APPARATUS - An ultrasound image diagnosis apparatus executing lighting-on and lighting-off of a lighting device by detecting an identification (ID) data of a probe or an operation on an operation panel. The ultrasound image diagnosis also includes a lighting device configured to identify a usage state or non-usage state of the ultrasound probe by a lighting color. While an ultrasound examination is performed in a dimly-lit room, a visibility of an ultrasound probe connector can be increased. | 2010-11-18 |
20100292578 | VEIN IMAGING APPARATUS, POSITIONAL DISPLACEMENT INTERPOLATION METHOD, AND PROGRAM - An imaging element of a vein imaging apparatus includes a vein image data generation region generating image data of a vein based a near-infrared light that was condensed by a lens array and that was scattered in a living body and transmitted through the vein and a positional displacement detection data generation region that includes a shielded section in which pixels are shielded from the light and an opening section in which pixels are not shielded from the light, and generates data for detecting positional displacement that is used to detect, based on the light received via the opening section, variation in an image focus position according to an imaging temperature. The vein imaging apparatus detects the image focus position of the light and estimates the amount of positional displacement occurred in the apparatus. The vein imaging apparatus selects a pixel based on the obtained amount of positional displacement. | 2010-11-18 |
20100292579 | VEIN IMAGING APPARATUS, VEIN IMAGE INTERPOLATION METHOD, AND PROGRAM - An imaging element of a vein imaging apparatus according to the invention includes a vein image data generation region for generating image data of a vein based on a near-infrared light that was condensed by a lens array and that was scattered in the living body and transmitted through the vein, and a thermal noise output data generation region that includes a pixel shielded from light and generates a thermal noise output that is an output value output from the pixel shielded from light. The vein imaging apparatus according to the present invention measures thermal noise based on the thermal noise output data, and estimates an imaging temperature based on a measurement result of this thermal noise. The vein imaging apparatus according to the present invention performs interpolation processing of the image based on the estimated temperature during imaging process. | 2010-11-18 |
20100292580 | SEPTIC BARRIERS AND OTHER AIDS FOR AUTOFLUORESCENCE VISUALIZATION AND OTHER OPTICAL INTERROGATION - Septic barriers interposed between a target tissue such as an oral or vaginal cavity, exposed epidermis, or wound or surgical site, and a user and his/her optical interrogation instruments to reduce cross-infection and/or contamination. In certain embodiments, the septic barrier is substantially transparent for viewing purposes and is typically effectively non-fluorescent, particularly when used for investigating autofluorescence or other fluorescence emanating from a target, so as to have little or no effect on the measurements and observations being made. The sepsis barrier can comprises a window through which the user sees the tissue, a frame holding the window, and an attachment structure, such as threads or bayonet attachment, configured to connect the barrier to the instrument. If desired, the system can also have an optional attachment mechanism for permanent or temporary connection of a further instrument to the frame, such as a tissue retractor configured to aid manipulation of the target tissue. | 2010-11-18 |
20100292581 | Dynamic Calibration of an Optical Spectrometer - A dynamically calibrating optical spectrometer and method for dynamically calibrating the optical spectrometer are provided. The optical spectrometer may include a band-pass device and a device that scans, such that a scan window can be widened, and the edges of the band-pass device can be used to calibrate out drifts in the system. The optical spectrometer may be for acquiring and analyzing a spectroscopic sample of an analyte from a sampling region of the tissue of a person. The optical spectrometer includes a tunable source of electromagnetic radiation, a probe for delivering the electromagnetic radiation to the tissue at the sampling region and obtaining a diffuse reflectance signal from the tissue at the sampling region, a spectroscopic detector for analyzing the diffuse reflectance signal for presence of the analyte, and a wavelength calibration detector for calibrating the tunable source of electromagnetic radiation to a desired wavelength. | 2010-11-18 |
20100292582 | TISSUE PROBE WITH SPEED CONTROL - A single use needle-like probe contains optical fibers to deliver and collect light at the distal tip of the needle-like probe. The single use needle-like probe may connect to a handpiece that may contain sensors to monitor how the probe is being used. Sensors within the handpiece may, e.g., include a force sensor and a position sensor that detect the depth of the probe in tissue. The handpiece may include a mechanism for limiting the maximum probe velocity. The handpiece may be connected through a cable to a control unit that may include light sources, optical detectors, control electronics and one or more microprocessors to analyze the data collected. | 2010-11-18 |
20100292583 | METHOD AND SYSTEM FOR SYNCHRONIZING BLOOD COMPONENT OR TRACE ANALYTE MEASUREMENT WITH HEART PULSE RATE - A system and method for measuring at least one blood component or trace analyte in the blood of a subject, the system including: a heart pulse rate measuring device for measuring a heart pulse rate of the subject, and a blood component or trace analyte measuring device for measuring the at least one blood component or trace analyte, wherein the blood component or trace analyte measuring device is synchronized with the heart pulse rate of the subject to perform a blood component or trace analyte measurement at a point along a measurement interval determined by the heart pulse rate. | 2010-11-18 |
20100292584 | SPECTRUM ANALYTICAL METHOD FOR QUANTIFYING HEAT-LUNG INTERACTION - The present invention is related to a spectrum analytical method for quantifying hear-lung interaction, which can estimate cardiac function by using a heart-associated monitoring signal. According to the method of the present invention, quantification of heart-lung interaction is conducted by choosing spectrum signals within a specified frequency band, such that the interference to the heart-associated monitoring signals by incidental events occurring at a low frequency, can be avoided. Therefore, the method of the present invention can be performed even in the subjects who are not in a state of general anesthesia or sedation, and hence is very useful in estimating the cardiac function of the test subjects. | 2010-11-18 |
20100292585 | LIVING BODY INFORMATION DETECTION APPARATUS AND BLOOD-PRESSURE METER - A living body information detection apparatus for detecting living body information at an auricle of a human body. The living body information detection apparatus having a shape that follows a cartilage of the auricle in a periphery of a concha auriculae. | 2010-11-18 |
20100292586 | Wireless automatic ankle-brachial index (AABI) measurement system - A central processor controlled system and test procedure for independently, contemporaneously and plethysmographically monitoring arterial blood pressure at a subject's arms and legs. Micro-controlled occluding and sensing cuffs containing sensors are inflated and deflated at each limb of a supine patient. Sensed AC and DC pressure data is wirelessly linked to the central processor where the DC sensor data is sampled to derive median filtered, fitted and derivative waveforms that are iteratively processed and scored to determine a table of sample indices indicative of lowest pressure point. Second scoring and fittings about the lowest pressure point at the DC sensor data and original occluding cuff pressure data identify each limb's systolic pressure. The derived systolic limb pressure values are then processed to determine right and left ABI values. | 2010-11-18 |