45th week of 2012 patent applcation highlights part 45 |
Patent application number | Title | Published |
20120283369 | Polymerization process in the presence of an antistatic agent - Process for the polymerization of olefins at temperatures of from −20 to 200° C. and pressures of from 0.1 to 20 MPa in the presence of a polymerization catalyst and an antistatic agent, wherein
| 2012-11-08 |
20120283370 | MOISTURE-CURABLE HOT MELT ADHESIVE - The present invention provides a method for producing a moisture-curable hot melt adhesive. This moisture-curable hot melt adhesive is environmentally friendly, is compatible with the components therein, has high initial adhesion strength, has long open time and has high heat resistance after moisture curing. The moisture-curable hot melt adhesive comprises a (A) urethane prepolymer having an isocyanate group at the terminus, comprising, a (A) urethane-modified rosin, and a (B) copolymer of ethylene and a (meth)acrylic acid derivative, wherein the urethane prepolymer is obtained by the reaction of polyol with an isocyanate compound. | 2012-11-08 |
20120283371 | OPTICAL FILMS CAST FROM STYRENIC FLUOROPOLYMER SOLUTIONS - A method for casting a styrenic fluoropolymer film on a substrate includes preparing a polymer solution by dissolving the fluoropolymer in a solvent or solvent blend whose Hansen solubility parameters (HSPs. MPa | 2012-11-08 |
20120283372 | Rubber Composition Including a Phenolic Resin - A rubber composition which can be used in particular in tires, based on at least one diene elastomer, one reinforcing filler, one crosslinking system, one phenolic resin and one polyaldehyde. The use of a polyaldehyde makes it possible to advantageously replace conventional methylene donors while preventing the production of formaldehyde during the vulcanization of the rubber compositions and thus to limit the environmental impact of these compounds. Furthermore, these polyaldehyde compounds make it possible not only to obtain rubber compositions exhibiting the same low-strain stiffness as conventional rubber compositions using HMT or H3M methylene donors but also, surprisingly, to greatly improve the fatigue strength of the rubber compositions and thus the endurance of the tires. | 2012-11-08 |
20120283373 | CURABLE COMPOSITIONS CONTAINING COLOR INDICATORS FOR INDICATING THE CURING PROGRESS - Curable compositions are prepared from polyol components containing one or more polyols and isocyanate components containing one or more isocyanates, which compositions contain at least one indicator having at least one quinonoid group, which indicator signifies the degree of curing by a change of color. A method is also provided for indicating the progress of curing in such curable compositions. | 2012-11-08 |
20120283374 | AQUEOUS DISPERSION OF HYBRID PARTICLES CONSISTING OF ORGANIC OR INORGANIC PIGMENT PARTICLES AND ORGANIC NANO-PARTICLES AND PROCESS FOR PREPARING THE SAME - An aqueous dispersion of hybrid particles consisting of inorganic or organic pigment particles and organic nano-particles attached to the surface of the pigment particles, the nano-particles having a particle size between 2 and 200 nanometers. Preferably the nano-particles have a glass transition temperature of at least 120° C. and comprise co-polymers of vinyl monomers and a mixture comprising maleic anhydride and derivates of maleic anhydride. In a process for preparing such an aqueous dispersion a copolymer of vinyl monomers and maleic anhydride is treated in water with a compound having the general formula R—NH | 2012-11-08 |
20120283375 | RESIN COMPOSITION - Resin compositions containing a polyisobutylene resin; a polyisoprene resin and/or a polyisobutylene resin, each having a functional group capable of reacting with an epoxy group; a tackifier resin; and an epoxy resin are useful for sealing OEDs. | 2012-11-08 |
20120283376 | ELECTRONIC INK MICROCAPSULE AND A METHOD FOR PRODUCING THE SAME - Embodiments of the disclosed technology provide an electronic ink microcapsule and a method for producing the same, wherein the electronic ink microcapsule comprises gelatin, polyanion, and an electrophoretic suspension, and the polyanion comprises a hydrolyzate of styrene-maleic anhydride-hexafluorobutyl methacrylate-vinyl triethoxysilane tetracopolymer. | 2012-11-08 |
20120283377 | ORGANIC ELECTRONIC DEVICES, INCLUDING ORGANIC PHOTOVOLTAIC DEVICES, POLYMERS, AND MONOMERS - Materials for organic electronic devices including organic photovoltaic devices. An oligomer or polymer comprising: | 2012-11-08 |
20120283378 | A SILICONE COMPOUND, PHOTOCURABLE LIQUID INK USING THE SILICONE COMPOUND, AND METHOD OF MANUFACTURING THE INK - A silicone compound represented by the following Chemical Structure 1: | 2012-11-08 |
20120283379 | SILICA PARTICLE INCLUDING A MOLECULE OF INTEREST, METHOD FOR PREPARING SAME AND USES THEREOF - What is provided includes a nanoparticle of porous silica, incorporating at least one molecule of interest, the silica network inside said nanoparticle being functionalized by at least one group capable of setting up an ionic and/or hydrogen non-covalent bond with the molecule of interest, whereby the molecule(s) of interest is(are) linked to the silica network solely by non-covalent bonds. In addition, a method for preparing said silica particle and uses thereof is provided. | 2012-11-08 |
20120283380 | RUBBER MIXTURE FOR ELASTIC COUPLING - The invention relates to an elastic coupling comprised of connecting flanges located on the drive input and drive output side as well as comprised of at least one rubber .body arranged between them. The invention proposes that the at least one rubber body contains silicic acid/silica as filler agent as well as dyeing pigments. | 2012-11-08 |
20120283381 | MACROINITIATOR CONTAINING HYDROPHOBIC SEGMENT - The present invention relates to macroinitiators comprising at least one hydrophobic segments in a molecule, wherein a molecular weight of the hydrophobic segment is 300 to 1800. The present invention further relates to block copolymers, wetting agent and polymeric materials having the block copolymers of the present invention associated with, which is suitable for medical devices, particularly for ophthalmic devices, including contact lenses, ophthalmic lenses, punctal plugs and artificial corneas. | 2012-11-08 |
20120283382 | Process for Manufacturing a Dispersion of a Vinylidene Fluoride Polymer - A process for manufacturing a dispersions of a vinylidene fluoride (VDF) thermoplastic polymer [polymer (F)], said process comprising polymerizing VDF in an aqueous phase comprising:
| 2012-11-08 |
20120283383 | Method for Manufacturing Fluoropolymers - The invention pertains to a process for manufacturing a (per)fluoropolymer, said process comprising polymerizing one or more fluorinated monomers in the presence of a multi-phase medium, said medium comprising:
| 2012-11-08 |
20120283384 | Non-Porous Thermoformable Polyurethane Solid - The subject disclosure presents systems and methods for manufacturing a non-porous thermoformable polyurethane solid by combining an uncured polyurethane resin with Aluminum Trihydrate (ATH), a plurality of particulates, molecular sieves, and color particulates. This combination is mixed in a vacuum for a time period sufficient to initiate an exothermic reaction within the mixture. After the time period, the exothermically reacting mixture is allowed to cure to form the polyurethane solid. The curing may occur in a mold, i.e. by pouring or injecting the mixture into the mold. Alternatively, the mixture may be sprayed on to a surface and allowed to cure. | 2012-11-08 |
20120283385 | STRUCTURE, TARGET SUBSTANCE-DETECTING ELEMENT AND TARGET SUBSTANCE-DETECTING KIT - According to the present invention, there can be provided a structure preventing the nonspecific adsorption, and a target substance-detecting element and a target substance-detecting kit. A first aspect of the present invention is a structure including: a substrate; and a membrane, present on the surface of the substrate, having a polymer of a monomer represented by the following General Formula (1) or (2): | 2012-11-08 |
20120283386 | ANTISTATIC AGENT AND RESIN COMPOSITION CONTAINING SAME - There is provided an antistatic agent that preserves its antistatic property for a long period of time and has the appearance and the transparency that are not impaired when kneaded into a resin, and a resin composition containing the antistatic agent. An antistatic agent including a block copolymer which is obtained from a reaction product of a polyolefin (a) having one end being acid-modified and a diol and/or a diamine (b) having a polyoxyalkylene chain, and in which a part or all of acid groups remaining in the reaction product is neutralized with an alkaline substance. A thermoplastic resin composition including the antistatic resin. A film or sheet including the thermoplastic resin composition. | 2012-11-08 |
20120283387 | METHOD FOR MAKING FUNCTIONALIZED POLYMER - A macromolecule includes at least one polymer chain and terminal functionality. The terminal functionality includes a ring-opened radical of a cyclosilazane or cyclic hydrosiloxane. The polymer can include unsaturated mer units and can be provided via anionic polymerization techniques. The macromolecule can be used as a component of a composition that also includes particulate fillers, with the composition being useful for the production of vulcanizates. | 2012-11-08 |
20120283388 | POLYOLEFINS MODIFIED BY SILICONES - The invention provides a process for grafting silicone onto a polyolefin comprising reacting the polyolefin with a silicon compound containing an unsaturated group in the presence of means capable of generating free radical sites in the polyolefin, characterized in that the silicon compound is a branched silicone resin containing at least one group of the formula —X—CH═CH—R″ (I) or —X—C≡C—R″ (II), in which X represents a divalent organic linkage having an electron withdrawing effect with respect to the —CH═CH— or —C≡C-bond and/or containing an aromatic ring or a further olefinic double bond or acetylenic unsaturation, the aromatic ring or the further olefinic double bond or acetylenic unsaturation being conjugated with the olefinic unsaturation of —X—CH═CH—R″ or with the acetylenic unsaturation of —X—C≡C—R″, X being bonded to the branched silicone resin by a C—Si bond, and R″ represents hydrogen or a group having an electron withdrawing effect or any other activation effect with respect to the —CH═CH— or —C□C-bond. The polyolefin is reinforced by grafting the branched silicone resin onto it. | 2012-11-08 |
20120283389 | FILM OF POLY(TRIMETHYLENE ARYLATE)/POLYSTYRENE BLENDS AND PROCESS FOR MAKING - A film of poly(trimethylene arylate) and a polystyrene wherein the polystyrene concentration is in the range of 0.5 to 40 weight %. Poly(trimethylene terephthalate) and polystyrene are particularly useful. Also, disclosed are processes for preparing the film. | 2012-11-08 |
20120283390 | HIGH MELT STRENGTH POLYETHYLENE COMPOSITIONS AND METHODS FOR MAKING THE SAME - The present invention is a method for increasing the melt strength of a polyethylene resin comprising reacting the polyethylene resin with a free radical generator with a decomposition energy in between −50 kJoule/mole and −250 kJoules/mole and a peak decomposition temperature of less than 280 degree C. The resulting resin has increased melt strength with higher ratio of elongational viscosities at 0.1 to 100 rad/s when compared to substantially similar polyethylene resins which have not been reacted with a free radical generator such as an alkoxy amine derivative. | 2012-11-08 |
20120283391 | BIODEGRADABLE THERMOPLASTIC ELASTOMERS - The present invention relates to a biodegradable thermoplastic elastomer having the general formula A-B-A wherein each A is an amorphous polymer having a glass transition temperature (Tg)>40° C. or a semi-crystalline polymer having a glass transition temperature (Tg) and/or melting temperature (Tm)>40° C.; B is a copolymer of -caprolactone (CL) and at least one additional monomer selected from the group consisting of L-lactic acid (LLA), trimethyl carbonate (TMC), and glycolic acid (GA), or B is different to A and is lactic-co-glycolic acid (LGA); and wherein the molar ratio of CL to the at least one additional monomer in the copolymer B is in the range between about 1:0.09 to about 1:1. | 2012-11-08 |
20120283392 | POLYESTER PROCESS - The present disclosure provides processes for the preparation of unsaturated polyesters. In embodiments, a process of the present disclosure includes reacting an organic diol with a cyclic alkylene carbonate in the presence of a first catalyst to thereby form a polyalkoxy diol, optionally adding thereto a further amount of cyclic alkylene carbonate in the presence of a second catalyst, and subsequently polycondensing the resulting mixture with a dicarboxylic acid in combination with an anhydride. | 2012-11-08 |
20120283393 | POLYCARBONATE-POLYORGANOSILOXANE COPOLYMER, PROCESS FOR PRODUCTION OF THE COPOLYMER, AND POLYCARBONATE RESIN CONTAINING THE COPOLYMER - The present invention is a polycarbonate-polyorganosiloxane copolymer (A-1) comprising a polycarbonate block composed of a specific structural unit and a polyorganosiloxane block composed of a specific structural unit, wherein
| 2012-11-08 |
20120283394 | Initiator Integrated Poly (Dimethylsiloxane) and Methods for Making the Same and Its Application - Disclosed herein is an initiator integrated polydimethylsiloxane (iPDMS). The iPDMS is a polydimethylsiloxane undergoing a hydrosilylation reaction. The initiator 10-undecenyl 2-bromo-2-methyl propionate is integrated on the surface of iPDMS by covalent bond. At % is 0.01-1% confirmed by X-ray photoelectron spectroscopy. Disclosed herein is a method for making an initiator integrated polydimethylsiloxane. Prepolymer A, cross-linker B and vinyl-terminated initiator C were mixed below a ratio of 10:1:4-0.01 for 6-24 hours, then the elastomer was formed. And, disclosed herein is functional surface modification of initiator integrated polydimethylsiloxane and its applications for biocompatibility, organic solvent compatibility and heat-sensitive materials. | 2012-11-08 |
20120283395 | CATALYST FEED CONTROL DURING CATALYST TRANSITION PERIODS - Techniques are provided for operating a reactor during a catalyst transition period. The instantaneous reaction rate during a catalyst transition period can be determined using real-time measured process variables, and material balance calculations to provide an instantaneous reaction rate in approximately real time. According to certain embodiments, a material balance can be performed on the reactor system using a continuous ideal stirred tank reactor to determine the fractions of each type of catalyst that are present in the reactor, as well as the overall weight percent of catalyst in the reactor. A controller can then calculate the overall instantaneous reaction rate based on the respective catalyst fractions and the overall weight percent of catalyst in the reactor. The catalyst feed rate can then be adjusted based on the determined instantaneous reaction rate to maintain the instantaneous reaction rate within desired limits during a catalyst transition period. | 2012-11-08 |
20120283396 | Process for the preparation of a multimodal polyolefin polymer with improved hydrogen removal - Process for the preparation of a multimodal polyolefin polymer at temperatures of from 40 to 150° C. and pressures of from 0.1 to 20 MPa in the presence of a polymerization catalyst in a first and a second polymerization reactor connected in series, wherein further polymerization reactors can be connected to said reactors upstream or downstream of said reactors, in which in the first polymerization reactor a first polyolefin polymer is prepared in suspension in the presence of hydrogen and in the second polymerization reactor a second polyolefin polymer is prepared in the presence of a lower concentration of hydrogen than in the first polymerization reactor, comprising
| 2012-11-08 |
20120283397 | STYRENE POLYMER AND MANUFACTURING METHOD THEREFOR - A method for manufacturing a styrene polymer having a low number average molecular weight and a low polydispersity index, wherein the polymer has a number average molecular weight of 2000 or less and a polydispersity index of 1.01 to 1.10. For this purpose, the method includes polymerizing a styrene monomer in a solvent comprising an ether group-containing solvent in the presence of a polymerization initiator represented by formula [II], an organometallic compound represented by formula [III], and an organic potassium compound, at a temperature between −10° C. or higher and a boiling point of the solvent or lower. | 2012-11-08 |
20120283398 | AIR AND WATER TOLERANT CATALYST - A catalyst and/or precatalyst for olefin oligomerization comprising one or more coordination complexes having one or more central palladium metal atoms. Each palladium atom is bonded to four ligand donor atoms. Two of the donor atoms are group 16 elements and two of the donor atoms are group 15 elements. Also provided are neutral or cationic coordination complex dimers, so that the two palladium atoms are both bonded to one or two donor atoms from group 16, and each palladium atom is bonded to two donor atoms from group 15. In some instances, each of the two group 16 donor atoms are oxygen and each of the four group 15 donor atoms are nitrogen. | 2012-11-08 |
20120283399 | PROCESS FOR PRODUCING SYNDIOTACTIC alpha-OLEFIN POLYMER - A process for producing a syndiotactic α-olefin polymer having high racemic diad fraction and high molecular weight with excellent polymerization activity through a method permitting high-temperature polymerization. The production process comprises polymerizing a monomer that comprises at least one C3-10 α-olefin and a small amount of ethylene, in the presence of an olefin polymerization catalyst comprising a transition metal compound (A) represented by the general formula [1], at least one compound (B) selected from an organoaluminum oxy-compound (b-1), a compound (b-2) that reacts with the transition metal compound (A) to form an ion pair and an organoaluminum compound (b-3), which process for producing a syndiotactic α-olefin polymer satisfies the relationship: 0.001≦P | 2012-11-08 |
20120283400 | Process for the Preparation of Supported Catalysts - The present invention refers to a process for the preparation of supported catalysts for the polymerization of olefins comprising at least a late transition metal complex, wherein the process comprises two steps. In the first step a catalytically active component comprising at least one late transition metal complex, optionally in the presence of one or more cocatalysts is mixed with a support; and in the second step the obtained mixture is treated at a reduced pressure under a flow of inert gas at a temperature equal to or below 40° C. to obtain a supported catalyst. The method is especially useful for the preparation of dual supported catalysts, useful in the gas-phase polymerization of olefins. | 2012-11-08 |
20120283401 | Process For Producing Water-Absorbing Polymer Particles - A process for producing water-absorbing polymer particles, comprising polymerization of a monomer solution or suspension, drying the resulting polymer gel, and grinding and classifying the dried polymer gel, wherein the grinding is performed by means of a multistage roll mill, the first milling gap has a width of 500 to 5000 μm, the product mass flow passing through the first milling gap is conducted through a magnetic separator to the second milling gap, and the second milling gap has a smaller gap width than the first milling gap. | 2012-11-08 |
20120283402 | Magnesium dichloride-water adducts and catalyst components obtained therefrom - Solid adducts comprising MgCl | 2012-11-08 |
20120283403 | Phenylboronic Acid Monomer and Phenylboronic Acid Polymer - Disclosed are a phenylboronic acid monomer and a phenylboronic acid polymer, each of which can have a pKa value suitable for the use under physiological environments and can be used for various applications. The pheanylboronic acid monomer has a structure represented by formula (13) and therefore has high hydrophilicity, can have a satisfactorily low pKa value when the phenyl ring is fluorinated, and can have a polymerizable unsaturated bond. The phenylboronic acid monomer has high hydrophilicity at a pKa value of 7.4 or less which is a physiological level, and can be polymerized with a wide variety of monomers to produce polymers suitable for the intended purposes. | 2012-11-08 |
20120283404 | Polynorbornene Pervaporation Membrane Films, Preparation and Use Thereof - Embodiments in accordance with the present invention provide forming polynorbornenes useful for forming pervaporation membranes, the membranes themselves and methods of making such membranes. | 2012-11-08 |
20120283405 | ETHERAMINES CONTAINING FLEXIBLE AND RIGID SEGMENTS AND THEIR USE AS INTERMEDIATES FOR POLYMER SYNTHESIS - The present invention relates to an etheramine mixture containing a monoether diamine and its method of production by alkyloxating an initiator with an alkylene oxide to produce a precursor polyol and reductively aminating the precursor polyol to form the etheramine mixture. The etheramine mixture may be used in variety of applications including as a curing agent for an epoxy resin or as a reactant in the production of polyurea materials. | 2012-11-08 |
20120283406 | COMPOSITION FOR ANIONIC LACTAM POLYMERIZATION - A composition comprising a) at least one aliphatic or cycloaliphatic isocyanate compound having at least two isocyanate groups and b) at least one lactone, containing 4 to 7 carbon atoms and use of the composition as an activator for anionic lactam polymerization to obtain polyamides. | 2012-11-08 |
20120283407 | New polyamide, polyimide or polyamide-imide comprising dibenzodiazocine units - The invention relates to polymers (P) of amides, imides, amides-imides or their derivates. The polymer (P) comprising recurring units (I) of one or more structural formula(e): -A-B-C-D- (I), wherein, A and C, identical or different from each other and from one structural formula to another, independently represent an amido group an imido group of formula or a mixture thereof; B, identical or different from one structural formula to another, is independently selected from the set consisting of C | 2012-11-08 |
20120283408 | FUSION PROTEIN BINDING SPECIFICALLY TO CONSTANT REGION OF ANTIBODY, METHOD OF PREPARING THE FUSION PROTEIN, AND METHOD OF ISOLATING ANTIBODY USING THE FUSION PROTEIN - A fusion protein that includes a polypeptide binding specifically to a constant region of an antibody and a stabilization protein linked to a terminus of the polypeptide, a polynucleotide encoding the fusion protein, a cell including the polynucleotide, a method of preparing the fusion protein, and a method of isolating an antibody by using the fusion protein. | 2012-11-08 |
20120283409 | COMPUTATIONALLY DESIGNED INHIBITORS OF AMYLOIDOSIS - Embodiments of the present invention include methods and systems for designing inhibitors of amyloidosis in humans, domesticated animals, and wild animals as well as inhibitors of amyloidosis designed by the methods and systems. Methods and systems for designing inhibitors of amyloidosis are largely computational, in nature, and are directed to designing various types of polymers, small-molecule organic compounds, organometallic compounds, or non-chemical physical processes that can target the extended-α-strand and α-sheet regions of amyloidogenic protein and polypeptide intermediates in order to prevent aggregation of those intermediates into protofibrils and fibrils that, in turn, recruit additional native-conformation proteins and polypeptides into amyloidogenic intermediates and that additionally aggregate to form higher-order structures, such as plaques observed in the brains of patients suffering from the various spongiform encephalopathies. | 2012-11-08 |
20120283410 | ATTACHMENT OF BIOLOGICAL TARGETING GROUPS USING METAL FREE CLICK CHEMISTRY - The present invention relates to the field of polymer chemistry and more particularly to click-functionalized targeting compounds and methods for using the same. | 2012-11-08 |
20120283411 | METHODS AND COMPOSITIONS FOR THE TREATMENT OF GASTROINTESTINAL DISORDERS - Compositions and related methods for treating IBS and other gastrointestinal disorders and conditions (e.g., gastrointestinal motility disorders, functional gastrointestinal disorders, gastroesophageal reflux disease (GERD), duodenogastric reflux, Crohn's disease, ulcerative colitis, inflammatory bowel disease, functional heartburn, dyspepsia (including functional dyspepsia or nonulcer dyspepsia), gastroparesis, chronic intestinal pseudo-obstruction (or colonic pseudoobstruction), disorders and conditions associated with constipation, e.g., constipation associated with use of opiate pain killers, post-surgical constipation, and constipation associated with neuropathic disorders and disorders and conditions associated with excess fluid and/or salt retention as well as other conditions and disorders are described. The compositions feature polypeptides that activate the guanylate cyclase C (GC-C) receptor. | 2012-11-08 |
20120283412 | ORPHAN NUCLEAR RECEPTOR - The present invention relates to a novel human orphan nuclear receptor that binds to a cytochrome P-450 monooxygenase (CYP) promoter and that is activated by compounds that induce CYP gene expression. The invention further relates to nucleic acid sequences encoding such a receptor, to methods of making the receptor and to methods of using the receptor and nucleic acid sequences encoding same. The invention also relates to non-human animals transformed to express the human receptor and to methods of using such animals to screen compounds for drug interactions and toxicities. | 2012-11-08 |
20120283413 | CHIMERIC, HYBRID AND TANDEM POLYPEPTIDES OF MENINGOCOCCAL NMB1870 - NMB1870 is a protein in Neisseria meningitidis. Three families of NMB1870 are known. To increase the ability of a NMB1870 protein to elicit antibodies that are cross-reactive between the families, NMB1870 is engineered. Sequences can be substituted from one NMB1870 family into the corresponding position in another family. Proteins of NMB1870 sequences from different families can be joined to each other. | 2012-11-08 |
20120283414 | Monoclonal Antibodies for Ebola and Marburg Viruses - Described herein are a number of Ebola and Marburg monoclonal antibodies. | 2012-11-08 |
20120283415 | Multivalent Antibodies - The present invention provides a multivalent antibody or a heavy/light chain component thereof comprising: a heavy chain comprising a constant region fragment, said constant region fragment located between two variable domains which are not a cognate pair, the heavy chain further comprising an Fc region with at least one domain selected from CH2, CH3 and combinations thereof, with the proviso that the heavy chain contains no more than one CH1 domain and only contains two variable domains, and a light chain comprising a constant region fragment located between two variable domains which are not a cognate pair, wherein said heavy and light chains are aligned to provide a first binding site formed by a first cognate pair of variable domains and a second binding site formed by a second cognate pair of variable domains. | 2012-11-08 |
20120283416 | WASH SOLUTION AND METHOD FOR AFFINITY CHROMATOGRAPHY - The invention provides a washing method for affinity chromatography in which a wash solution comprising arginine, or an arginine derivative, and a nonbuffering salt, preferably at high pH, greater than 8.0, is effective in removing impurities, such as high molecular weight species and host cell proteins, while also increasing product concentration in the eluate and maintaining a high percent yield of recovered product. | 2012-11-08 |
20120283417 | POLYPEPTIDES COMPRISING Fc FRAGMENTS OF IMMUNOGLOBULIN G (IgG) AND METHODS OF USING THE SAME - Polypeptides comprising at least a first and second Fc fragment of IgG that can be used to induce a stimulated cell to produce the anti-inflammatory cytokine Interleukin-10 and methods of using the same are disclosed herein. | 2012-11-08 |
20120283418 | COVALENT DISULFIDE-LINKED DIABODIES AND USES THEREOF - The present invention provides recombinant antibody fragments which include a variable domain which has been modified by the addition of a tail sequence to its C-terminal end. The tail sequence comprises a terminal cysteine residue and an amino acid spacer and does not substantially affect the fragment's target-binding affinity. The present invention also provides pharmaceutical compositions comprising the described antibody fragments and a pharmaceutically acceptable carrier and methods of delivering an agent to cells of interest in a subject using the fragments as delivery vehicles. The invention further provides compositions comprising the described antibody fragments for the in vitro detection and measurement of target molecules which bind to the fragments and method of determining the presence or amount of such targets in a biological sample by contacting the sample with such compositions. | 2012-11-08 |
20120283419 | Separation of protein monomers from aggregates by solid weak anion exchange support functionalized with amine moieties - A flow-through process for separating protein monomer from aggregates of that protein in a solution containing both protein monomer and aggregates of that protein, the process includes the steps of | 2012-11-08 |
20120283420 | Production of Multi-Antennary N-Glycan Structures in Plants - The invention provides methods for producing multi-antennary glycoproteins in plant and plant cells. In particular the invention provides plants comprising a chimeric gene comprising glucosaminyltransferase IV and plants comprising two chimeric genes comprising glucosaminyltransferase IV and V. | 2012-11-08 |
20120283421 | METHODS AND REAGENTS FOR DECREASING CLINICAL REACTION TO ALLERGY - It has been determined that allergens, which are characterized by both humoral (IgE) and cellular (T-cell) binding sites, can be modified to be less allergenic by modifying the IgE binding sites. The IgE binding sites can be converted to non-IgE binding sites by altering as little as a single amino acid within the protein, preferably a hydrophobic residue towards the center of the IgE epitope, to eliminate IgE binding. Additionally or alternatively a modified allergen with reduced IgE binding may be prepared by disrupting one or more of the disulfide bonds that are present in the natural allergen. The disulfide bonds may be disrupted chemically, e.g., by reduction and alkylation or by mutating one or more cysteine residues present in the primary amino acid sequence of the natural allergen. In certain embodiments, modified allergens are prepared by both altering one or more linear IgE epitopes and disrupting one or more disulfide bonds of the natural allergen. In certain embodiments, the methods of the present invention allow allergens to be modified while retaining the ability of the protein to activate T-cells, and, in some embodiments by not significantly altering or decreasing IgG binding capacity. The Examples provided herein use peanut allergens to illustrate applications of the invention. | 2012-11-08 |
20120283422 | Ethanol Production Process - An improved ethanol production process providing novel stillage treatment is disclosed wherein the stillage is separated into four value added product streams that are subjected to drying conditions reducing or eliminating volatization of any VOC's in the product streams. | 2012-11-08 |
20120283423 | APPARATUS, SYSTEM AND METHOD FOR PURIFYING NUCLEIC ACIDS - Methods and devices for isolating nucleic acids from a mixture containing such nucleic acids and extraneous matter are provided. In one embodiment, the method of the invention comprises passing the mixture through a glass frit under conditions effective to separate the nucleic acids from the extraneous matter. In a more specific embodiment, the glass frit is a sintered glass frit. | 2012-11-08 |
20120283424 | REDUCTION OF OFF-TARGET RNA INTERFERENCE TOXICITY - The present invention is directed to RNA interference (RNAi) molecules targeted against a nucleic acid sequence, and methods of using these RNAi molecules to reduce off-target toxicity. | 2012-11-08 |
20120283425 | Isolated genomic polynucleotide fragments that encode human lipoprotein-associated phospholipase A2 - The invention is directed to isolated genomic polynucleotide fragments that encode human lipoprotein-associated phospholipase A2, vectors and hosts containing the fragment and fragments hybridizing to noncoding regions as well as antisense oligonucleotides to these fragments. The invention is further directed to methods of using these fragments to obtain human lipoprotein-associated phospholipase A2 and to diagnose, treat, prevent and/or ameliorate a pathological disorder. | 2012-11-08 |
20120283426 | Methods and Kit for Isolating Nucleic Acids - The present invention is related to a method for isolating a target nucleic acid from a sample comprising said target nucleic acid, comprising the steps of mixing a sample containing said target nucleic acid with a binding solution and a nucleic acid binding matrix, binding at least part of said target nucleic acid to said nucleic acid binding matrix, wherein said nucleic acid binding matrix is treated simultaneously or has been previously treated with at least one compound comprising a metal substance selected from the group consisting of metals of the main groups 13 to 16, semimetals and transition metals for reducing non-target nucleic acid contaminations or wherein said nucleic acid binding matrix is modified with hydrophobic groups. Furthermore, respective kits and reagents are provided with the teaching of the present invention. | 2012-11-08 |
20120283427 | CATIONIC DEXTRAN POLYMER DERIVATIVES - Cationic dextran polymer derivatives including an ester-linked amine-containing substituent and an alkyl ester substituent and methods for making such dextran polymer derivatives are disclosed. | 2012-11-08 |
20120283428 | HYALURONIC ACID DERIVATIVE EFFECTIVE AGAINST ATOPIC DERMATITIS, AND METHOD FOR MANUFACTURING SAME - Disclosed are a hyaluronic acid derivative effective against atopic dermatitis, and a method for manufacturing same. The method for manufacturing the hyaluronic acid derivative of the present invention comprises: a first step of chlorinating ascorbic acid; a second step of producing a tetrabutylamonium hydroxide (TBA) salt of hyaluronic acid; and a third step of conjugating the ascorbic acid chlorinated in the first step and the TBA salt of hyaluronic acid produced in the second step. The hyaluronic acid derivative can effectively decrease the substances causing skin lesions, can contribute toward the remission of atopic disease, and is effective in skin renewal. | 2012-11-08 |
20120283429 | Biodegradable Hyaluronic Acid Derivative - The description provides a biodegradable hyaluronic acid derivative including at least one modified hyaluronic acid repeating unit represented by the formula (HA)-[O(C═O)NH-M]p, wherein HA is a unit including N-acetyl-D-glucosamine and D-glucuronic acid, M is a modifying moiety containing a C | 2012-11-08 |
20120283430 | System and Method for Fluoroalkylated Fluorophthalocyanines With Aggregating Properties and Catalytic Driven Pathway for Oxidizing Thiols - Organo-metallic materials with reduced steric hindrance and the ability to aggregate ar disclosed. The metal remains capable of binding additional molecules. As an example, Zn complexes that prove aggregation are provided. Such aggregation may help improve or trigger new surface properties of the materials, alone or in combination with others. In a further implementation of the present disclosure, a robust molecule that resists degradation via nucleophilic, electrophilic and radical attacks is provided. Coordinated O | 2012-11-08 |
20120283431 | PROCESSES FOR THE PREPARATION OF 8-CHLORO-1-METHYL-2,3,4,5-TETRAHYDRO-1H-3-BENZAZEPINE AND INTERMEDIATES RELATED THERETO - The present invention provides processes, methods and intermediates for the preparation of 8-chloro-1-methyl-2,3,4,5-tetrahydro-1H-3-benzazepine, salts, hydrates and crystal forms thereof which are useful as serotonin (5-HT) receptor agonists for the treatment of, for example, central nervous system disorders such as obesity. | 2012-11-08 |
20120283432 | USE OF RYLENE DERIVATIVES AS PHOTOSENSITIZERS IN SOLAR CELLS - Use of rylene derivatives I | 2012-11-08 |
20120283433 | NOVEL PROCESSES FOR THE PREPARATION OF CYCLOPROPYL-AMIDE DERIVATIVES - The present invention is directed to novel processes for the preparation of cyclopropyl-amide derivatives, useful for the treatment of disorders and conditions mediated by the histamine receptor. | 2012-11-08 |
20120283434 | PROCESS FOR THE PREPARATION OF RIVAROXABAN AND INTERMEDIATES THEREOF - A process for the preparation of rivaroxaban, or a pharmaceutically acceptable salt thereof, or a solvate thereof, including a hydrate, comprising submitting an amine compound of formula (III) wherein R | 2012-11-08 |
20120283435 | NOVEL ORGANIC/INORGANIC HYBRID DMOF-1-N3 SOLID PROVIDED WITH AN AZIDE FUNCTION, AND METHOD FOR PREPARING SAME - The invention describes a crystallized hybrid solid with an organic-inorganic matrix, of three-dimensional structure, containing an inorganic network of zinc-based metal centers connected to one another by organic ligands constituted by the entities —O | 2012-11-08 |
20120283436 | FACILE PREPARATION OF 4-SUBSTITUTED QUINAZOLINES AND RELATED HETEROCYCLES - A straightforward single step method for the preparation and/or production of substituted quinazolines is disclosed, wherein said quinazolines preferably contain one substituent at position 4, and may contain other functional groups at various positions, such as 5, 6, 7, and/or 8 of quinazolines. In addition, the extension of this new method leads to the formation of different type of heterocyclic aromatic compounds, that include but are not limited to perimidines, anthrapyrimidin-7-ones (also known as anthrapyrimidinones), anthra[1,9:5,10]dipyrimidines (also known as quinazoline[5,4-ef]perimidines) and benzo[e]-pyrimido[4,5,6-gh]pyrimidines. | 2012-11-08 |
20120283437 | Organic Electronic Device Comprising an Organic Semiconducting Material - The present invention relates to an organic electronic device comprising an organic semiconducting material comprising at least one compound according to the formulae (I) to (II). | 2012-11-08 |
20120283438 | COMPOUNDS - The present invention includes novel compounds useful in the treatment of various disorders in particular infectious diseases, cancer, and allergic diseases and other inflammatory conditions for example allergic rhinitis and asthma, and as vaccine adjuvants. | 2012-11-08 |
20120283439 | ISOXAZOLE/ISOXAZOLINE/COMBRETASTATIN LINKED DIHYDROQUINAZOLINONE HYBRIDS AS POTENTIAL ANTICANCER AGENTS AND PROCESS FOR THE PREPARATION THEREOF - The present invention provides a compound of general formulae 3a-i to 6a-i, 7a-i to 10a-i, 12a-i to 15a-i, 16a-i to 19a-i, 21a-i to 24a-i, 25a-i to 28a-i, 30a-i to 33a-i, 34a-i to 37a-i and 39a-i to 42a-i, 43a-i to 46a-i useful as potential antitumour agents against human cancer cell lines and a process for the preparation thereof. | 2012-11-08 |
20120283440 | CRYSTALLINE FORMS OF BOSENTAN SALTS AND PROCESSES FOR THEIR PREPARATION - The present invention relates to crystalline forms of bosentan salts and processes for their preparation.(FORMULA) | 2012-11-08 |
20120283441 | Method For Producing Pyrimidinylpyrazole Compounds - The present invention provides a method for producing a pyrimidinylpyrazole compound (1), wherein aminoguanidine (2) or its salt is reacted with a β-diketone compound (3) to produce the pyrimidinylpyrazole compound: | 2012-11-08 |
20120283442 | NOVEL CHEMICAL COMPOUNDS CAPABLE OF COMPLEXING AT LEAST ONE METAL ELEMENT AND A COORDINATION COMPLEX BASED ON THESE COMPOUNDS - The invention relates to compounds fitting the following formula (I): | 2012-11-08 |
20120283443 | Processes and Intermediates in the Preparation of Morphine Analogs via N-Demethylation of N-Oxides Using Cyclodehydration Reagents - A high-yielding method for the N-demethylation of oxycodone- and oxymorphone-N-oxides by the reaction of these compounds with cyclodehydration reagents has been performed. This method has been utilized to improve the synthesis of various morphine analogs, such as naltrexone, nalbuphone and naloxone. | 2012-11-08 |
20120283444 | PROCESS FOR THE PREPARATION OF MORPHINE ANALOGS VIA METAL CATALYZED N-DEMETHYLATION/FUNCTIONALIZATION AND INTRAMOLECULAR GROUP TRANSFER - The present application is directed to an efficient conversion of C-14 hydroxylated morphine alkaloids to various morphine analogs, such as naltrexone, naloxone and nalbuphone. One feature of this process is an intramolecular functional group transfer from the C-14 hydroxyl to the N-17 nitrogen atom following a palladium-catalyzed N-demethylation. | 2012-11-08 |
20120283445 | [4-(5-AMINOMETHYL-2-FLUORO-PHENYL)-PIPERIDIN-1-YL]-[7-FLUORO-1-(2-METHOXY-- ETHYL)-4-TRIFLUOROMETHOXY-1H-INDOL-3-YL]-METHANONE AS AN INHIBITOR OF MAST CELL TRYPTASE - The present invention is directed to an indole benzylamine compound of formula I: | 2012-11-08 |
20120283446 | METHOD FOR SYNTHESIZING BIO-BASED PYRIDINE AND PICOLINES - The present invention relates to a method for synthesizing bio-based pyridine and picolines, said method including at least the following steps: a first step involving subjecting a glycerol filler, created from the methanolysis of vegetable oils or animal fats, to a dehydration reaction leading to acrolein; a second step involving partial condensation of the effluent from the first step so as to separate a water-rich flow as well as an acrolein-rich flow; and a third step involving reacting the acrolein from the preceding step with acetaldehyde in the presence of ammonia so as to obtain, by means of a condensation reaction, the biobased pyridine and picolines. | 2012-11-08 |
20120283447 | METHOD FOR PRODUCING NANOPARTICLES - Provided is a method for producing a nanoparticle. Provided especially is, in the method for producing a nanoparticle to separate a diketopyrrolopyrrole pigment, a method for separating an α-type diketopyrrolopyrrole pigment nanoparticle having high crystallinity by carrying out separation of the diketopyrrolopyrrole pigment and crystal type transformation to the α-type with substantially a single step. The α-type diketopyrrolopyrrole pigment nanoparticle is separated by mixing a diketopyrrolopyrrole pigment solution having the diketopyrrolopyrrole pigment dissolved in a solvent and an alcohol solvent containing an alcohol compound solvent in a thin film fluid formed between at least two processing surfaces | 2012-11-08 |
20120283448 | METHOD FOR PRODUCING 3,4-DISUBSTITUTED PYRROLIDINE DERIVATIVE AND PRODUCTION INTERMEDIATE THEREOF - Provided is an inexpensive and industrially advantageous method for preparing (3R,4S)-3-(N-substituted aminomethyl)-4-fluoropyrrolidine or an enantiomer thereof which can be an intermediate for producing pharmaceuticals. It relates to a method for preparing (3R,4S)-3-(N-substituted cyclopropylaminomethyl)-4-fluoropyrrolidine derivative or ait's enantiomer, or their salts, comprising a step of fluorinating a 4-hydroxy-3-(N-substituted aminomethyl)pyrrolidine derivative represented by the general formula (1) or an enantiomer thereof using a sulfur tetrafluoride derivative. | 2012-11-08 |
20120283449 | METHOD FOR CARRYING OUT SEQUENTIAL REACTIONS USING A HEATING MEDIUM HEATED BY MEANS OF INDUCTION - A method for performing at least two successive chemical reactions to produce a target compound from at least one first, and at least one second and/or a further reactant, comprising a first reaction and a further reaction in a reaction medium, the reaction medium in contact with a solid heating medium heated by electromagnetic induction and which is located inside the reactor and surrounded by the reaction medium, and the heating medium being heated by electromagnetic induction with the aid of an inductor, an intermediate compound being formed in a first reaction, from which the target compound forms in a further reaction, and at least one reactant, not present in the reactor before the first reaction, being added between the first and the further reaction, and the target compound being separated from the heating medium. | 2012-11-08 |
20120283450 | COMPOUNDS INCLUDING AN ANTI-INFLAMMATORY PHARMACORE AND METHODS OF USE - This invention provides novel compounds comprising the following anti-inflammatory pharmacore: | 2012-11-08 |
20120283451 | PROCESS FOR THE PREPARATION OF F-SERIES PROSTAGLANDINS - A process for the synthesis and purification of F-series prostaglandin compounds and synthetic intermediates used to prepare them. The synthetic intermediates are solid and may be purified by precipitation and therefore may form the representative F-series prostaglandin compounds such as latanoprost, bimatoprost, fluprostenol, cloprostenol, and substituted analogs therefrom in highly pure forms. | 2012-11-08 |
20120283452 | METHOD FOR THE PREPARATION OF 2,5-FURANDICARBOXYLIC ACID AND ESTERS THEREOF - A method for the preparation of 2,5-furandicarboxylic acid (“FDCA”) and/or an alkyl ester of FDCA includes the step of contacting a feed comprising a starting material selected from 5-alkoxymethylfurfural, 2,5-di(alkoxymethyl)furan and a mixture thereof with an oxidant in the presence of an oxidation catalyst. The feed may also comprise 5-hydroxymethylfurfural as a further starting material. | 2012-11-08 |
20120283453 | PRODUCTION OF EPOXY RESINS USING IMPROVED ION EXCHANGE RESIN CATALYSTS - Use a modified, amine-functionalized anion exchange resin as a catalyst to produce a bishalohydrin ether and then dehydrohalogenate the bishalohydrin ether with an aqueous inorganic hydroxide mixture to yield a liquid epoxy resin. | 2012-11-08 |
20120283454 | PROCESS FOR PRODUCING OLEFIN OXIDE - A process for producing an olefin oxide which comprises reacting an olefin with oxygen in the presence of a catalyst comprising (a) copper oxide, (b) ruthenium metal or ruthenium oxide and (c) alkaline metal component or alkaline earth metal component. | 2012-11-08 |
20120283455 | PROCESS FOR PRODUCING OLEFIN OXIDE - A process for producing an olefin oxide which comprises reacting an olefin with oxygen in the presence of a catalyst comprising a copper oxide and a ruthenium oxide on a porous support. | 2012-11-08 |
20120283456 | NOVEL ORGANIC/INORGANIC HYBRID SOLID IHM-2-N3 PROVIDED WITH AN AZIDE FUNCTION, AND METHOD FOR MANUFACTURING SAME - The invention describes a crystallized hybrid solid with an organic-inorganic matrix, of a three-dimensional structure, containing an inorganic network of indium-based metal centers that are connected to one another by organic ligands that consist of the entity —O | 2012-11-08 |
20120283457 | HIGH-PRESSURE EXTRACTION APPARATUS AND METHOD - A high pressure extraction apparatus and extracting method therefor are adapted to maintain a medium at the supercritical state to extract substance-to-be-extracted. The apparatus includes an extraction tank, a piston and a control unit. The control unit controls the piston to reciprocate in the extraction tank as well as controls the pressure of the extract space of the tank, feeding of the substance, discharge of extract, and discharge of leftover. Accordingly, the apparatus performs a continuous supercritical extraction. | 2012-11-08 |
20120283458 | SOURCING PHOSPHORUS AND OTHER NUTRIENTS FROM THE OCEAN VIA OCEAN THERMAL ENERGY CONVERSION SYSTEMS - Provided herein are controlled methods for producing biofuel and lipids from algae. In certain embodiments, the controlled methods comprise: (i) providing upwelled water in a body of water; (ii) culturing algae in the upwelled water; (iii) feeding the algae to planktivorious organisms; (iv) extracting lipids from the planktivorious organisms; and (v) polishing the lipids to make biofuel or other useful products. In certain embodiments, the upwelled water is provided in the body of water by using an open-cycle OTEC system. Also provided herein are controlled systems for producing biofuel and lipids from algae. | 2012-11-08 |
20120283459 | METALOXIDE - Zr02 CATALYSTS FOR THE ESTERIFICATION AND TRANSESTERIFICATION OF FREE FATTY ACIDS AND TRIGLYCERIDES TO OBTAIN BIO-DIESEL - Mixed metal oxide catalysts (ZnO, CeO, La2O3, NiO, Al203, Si02, TiO2, Nd2O3, Yb2O3, or any combination of these) supported on zirconia (ZrO2) or hydrous zirconia are provided. These mixed metal oxide catalysts can be prepared via coprecipitation, impregnation, or sol-gel methods from metal salt precursors with/without a Zirconium salt precursor. Metal oxides/ZrO2 catalyzes both esterification and transesterification of oil containing free fatty acids in one batch or in single stage. In particular, these mixed metal oxides supported or added on zirconium oxide exhibit good activity and selectivity for esterification and transesterification. The low acid strength of this catalyst can avoid undesirable side reaction such as alcohol dehydration or cracking of fatty acids. Metal oxides/ZrO2 catalysts are not sensitive to any water generated from esterification. Thus, esterification does not require a water free condition or the presence of excess methanol to occur when using the mixed metal oxide catalyst. The FAME yield obtained with metal oxides/ZrO2 is higher than that obtained with homogeneous sulfuric acid catalyst. Metal oxides/ZrO2 catalasts can be prepared as strong pellets and in various shapes for use directly in a flow reactor. Furthermore, the pellet has a strong resistance toward dissolution to aqueous or oil phases. | 2012-11-08 |
20120283460 | Renewable Chemical Production From Novel Fatty Acid Feedstocks - Disclosed herein are methods of manufacturing renewable chemicals through the manufacture of novel triglyceride oils followed by chemical modification of the oils. Methods such as transesterification, hydrogenation, hydrocracking, deoxygenation, isomerization, interesterification, hydroxylation, hydrolysis and saponification are disclosed. Novel oils containing fatty acid chain lengths of C8, C10, C12 or C14 are also disclosed and are useful as feedstocks in the methods of the invention. | 2012-11-08 |
20120283461 | PASTEURISATION PROCESS FOR MICROBIAL CELLS AND MICROBIAL OIL - A pasteurisation protocol for pasteurising microbial cells is disclosed. The protocol has a heating stage, a plateau stage at which the cells are held at a (maximum and) constant temperature, and a cooling stage. The heating and cooling stages are rapid, the temperature of the cells passing through 40 to 80° C. in no more than 30 minutes in the heating stage. The heating rate is at least 0.5° C./minute and during cooling is at least −0.5° C./minute. The plateau maximum temperature is from 70 to 85° C. By plotting the pasteurisation protocol on a time (t, minutes) versus temperature (T, ° C.) graph, one obtains a trapezium having an area less than 13,000° C. minute. This results in a smaller energy input (so a reduction in costs) and a better quality (and less oxidised) oil having a peroxide value (POV) of less than 1.5 and an anisidine value (AnV) of less than 1.0. | 2012-11-08 |
20120283462 | NANOPARTICLES HAVING REDUCED LIGAND SPHERES - The invention relates to the technical field of nanoparticles. The subject matter of the invention is a method for treating nanoparticles for the reduction of ligand spheres. | 2012-11-08 |
20120283463 | INTERMEDIATE COMPOUNDS AND PROCESSES FOR THE PREPARATION OF TAPENTADOL AND RELATED COMPOUNDS - The present invention discloses processes for the preparation of 3-[(1R,2R)-3-(dimethyl-amino)-1-ethyl-2-methyl-propyl]phenol (Tapentadol), salts thereof and related compounds of formula (A), including stereoisomers and pharmaceutically acceptable salts thereof, and to certain intermediates used in such process. | 2012-11-08 |
20120283464 | PROCESS FOR THE PRODUCTION OF HIGH-PURITY DIMETHYL CARBONATE - A process for producing a high-purity dimethyl carbonate, which includes: (I) cooling a commercial grade dimethyl carbonate containing 1 ppm or more of chlorine to a temperature from +6° C. to −5° C. at a rate from 0.5-2° C./hour, to obtain a first solid dimethyl carbonate; (II) heating the first solid dimethyl carbonate to a temperature from −5° C. to +6° C. at a rate of 1-5° C./hour, to obtain a mixture comprising a second solid dimethyl carbonate and a predetermined amount of a first liquid dimethyl carbonate; (III) separating the first liquid dimethyl carbonate from the mixture, to obtain the second solid dimethyl carbonate; (IV) heating the second solid dimethyl carbonate to a temperature from 20° C. to 40° C., to obtain a second liquid dimethyl carbonate, wherein the second liquid dimethyl carbonate has a purity degree higher than 99.99% and a chlorine content lower than or equal to 1 ppm. | 2012-11-08 |
20120283465 | Oligomerisation Process - The startup of a tubular reactor containing fresh or regenerated molecular sieve catalyst and cooled by steam generation on the shell side, as part of an olefin oligomerisation process, is improved by, during the startup phase of the reactor, controlling the pressure on the shell side of the reactor at maximum 10 barg. The startup may be further improved by controlling the inlet temperature of the hydrocarbon startup stream to the reactor, by controlling the flow of reactant olefins to the reactor, or by controlling the nature and/or concentration of the olefins in the reactor feed. | 2012-11-08 |
20120283466 | LACOSAMIDE INTERMEDIATE COMPOUND, PREPARATION METHOD THEREOF AND USE THEREOF - A new compound is provided, which is used for preparing lacosamide. A novel method for preparing lacosamide is also provided. During the reaction, iodomethane and silver oxide that are cost expensive are not used, nor a Pd-c catalyst is used, so the production cost is low, the raw materials and accessory materials are cheap and easily available, and the process is simple, so that industrial production is easy to realize; and moreover, the yield is high, and good economic efficiency can be achieved. | 2012-11-08 |
20120283467 | NOVEL METHOD FOR PREPARING POLYOLS BY MEANS OF THIOLATION AND PRODUCTS SUCH AS THOSE OBTAINED - A method for preparing a polyol having the following general formula (I): the method including a step of transesterification followed by a step of thiolation. The present invention also relates to polyols with the formula (T) such as those defined above. | 2012-11-08 |
20120283468 | Preparation of substituted 2-fluoroacrylic acid derivatives - The present invention relates to a process for the preparation of substituted 2-fluoroacrylic acid derivatives. | 2012-11-08 |