45th week of 2012 patent applcation highlights part 42 |
Patent application number | Title | Published |
20120283068 | SELF-GENERATING RESISTANCE APPARATUS FOR FITNESS AND REHABILITATION EQUIPMENTS - A self-generating resistance apparatus for fitness and rehabilitation equipments comprises a bracket, a flywheel, a power generator, a belt and a resistance mechanism. The flywheel is rotating mechanism that provides inertia, and has a transmission shaft coupled to the power source of the fitness or rehabilitation equipment, and an external ring coupled to a pulley of the power generator by a belt. When a user steps on an exercise mechanism of the equipment, the flywheel drives the power generator to rotate and generate electric current. Since the power generator is installed outside the flywheel, the difference between the diameters of the pulley and the external ring causes a very large rotating speed ratio, and a large power approaching to the power generated by a large power generator can be produced. | 2012-11-08 |
20120283069 | JAW STRENGTHENING DEVICE - A jaw strengthening device may have an upper mouthpiece and a lower mouthpiece. These mouthpieces may be attached to each other by way of a coil compression spring. This allows the upper and lower mouthpieces to shift front and back as well as laterally so that the upper and lower mouthpieces do not track a specific pivot point, but can follow the natural movement of the jaw. A film is wrapped around the spring and expands outwardly as the user bites down on the mouthpieces to push the inside surface of the person's cheek away from the coils of the spring and prevent the coils of the spring from pinching the user's cheek. Additionally, the device may be inserted inside the person's mouth so that the device is not aesthetically obtrusive. | 2012-11-08 |
20120283070 | TREADMILL FOLDABLE INTO A CHAIR - A treadmill foldable into a chair includes a treadmill body having a base and a treadmill belt wound around the base, a stand having left and right symmetric support frames, and the bottom of the two support frames being pivotally coupled to the base by a pivot portion, and a meter installed at the top of the stand for adjusting and controlling an exercise status of the treadmill body, such that when the treadmill body is being used, the stand is erected at a front section of the base. The treadmill further includes a backrest installed between the two support frames, such that when the stand is folded towards the rear by using the pivot portion as an axial center, the stand is converted into a chair disposed on the base. The invention provides a two-in-one function and serves as a chair when not being used as a treadmill. | 2012-11-08 |
20120283071 | Weight plate with center post locking cartridge - A weight plate for use with physical fitness weightlifting equipment so that the weight plate may be coupled to other weight plates and lifted together in a stack. Each weight plate includes a pivotal switch arm including a first end at which to receive a pushing force to cause the switch arm to rotate relative to the weight plate and an opposite end at which a curved fork is carried. In one embodiment, a center post runs continuously through the center bore holes of the weight plates. In another embodiment, an insert is located in the center bore hole of each weight plate to be mated to the insert from an adjacent plate. When the pivotal switch arm of any weight plate is rotated to a locked position, the curved fork is rotated with the switch arm into surrounding engagement with the center post or the insert. | 2012-11-08 |
20120283072 | WEIGHT TRAINING DEVICE AND METHOD OF USE - A weight training device comprising a hollow tubular body. A plurality of handle wells disposed in the hollow tubular body. A plurality of handles disposed in the handle wells, wherein the plurality of handles comprise axially-oriented handles and circumferentially-oriented handles, and wherein the axially-oriented handles are diametrically opposed to the circumferentially-oriented handles. A fill cap well disposed in the hollow tubular body. A fill cap disposed in the fill cap well and removably attached to the hollow tubular body, wherein the fill cap is threaded and is attached to a threaded extrusion of the hollow tubular body. A plurality of baffles disposed within the hollow tubular body, wherein the hollow tubular body is configured to be used partially filled with a fill material so as to create a randomly variable weight distribution. Two diametrically-opposed end caps are attached to the axial ends of the hollow tubular body. | 2012-11-08 |
20120283073 | APPARATUS AND METHOD FOR STRENGTH CONDITIONING - An apparatus for conditioning and strengthening an individual comprising a housing defining a fluid retaining chamber adapted to receive fluid such that the housing can be provided with a predetermined weight and at least two handles extending from the housing. The handles are spatially disposed on the housing so as to permit the individual to lift the housing. The housing and corresponding fluid retaining chamber each have a substantially hourglass profile viewed from the upper side and the lower side. Also, the housing further comprises at least two openings extending through the housing from the upper side to the lower side and equally spaced on opposite sides of a center line of the housing, and each of the openings is traversed by one of the handles. | 2012-11-08 |
20120283074 | SYSTEM AND METHOD FOR CONTROLLING A STACK PIN IN A WEIGHT STACK OF AN EXERCISE MACHINE AND FOR PROVIDING ANATOMICALLY CORRECT BODY MOVEMENT ON AN EXERCISE MACHINE - A system for controlling a free end of a stack pin used with a stack of weights, the system including a nesting device configured to secure the free end of a stack pin when the stack pin is not lifting a weight and a tuning device configured to adjust the nesting device to exert a back up pressure on the stack pin to counteract potential energy that accumulates when the stack pin is being used to lift the weight. | 2012-11-08 |
20120283075 | WEIGHTLIFTING SYSTEM - A weightlifting system includes a weight bar frame rack having a first frame member that extends along a longitudinal axis. The first frame member includes a front face, a first side face, a second side face and a multiple of opposed pairs of openings disposed along the longitudinal axis. Each of the multiple of opposed pairs of openings are generally L-shaped and include a first opening and a second opening. A bracket assembly includes a mount having a first mount plate and a second mount plate spaced from the first mount plate. The first mount plate and the second mount plate are engageable relative to at least two opposed pairs of openings of the multiple of opposed pairs of openings. | 2012-11-08 |
20120283076 | WHEELCHAIR GYM - A wheelchair gym having a support bar releasably connected to the frame of the wheelchair. A vertical post is attached to the support bar and hand grips are slidably mounted on the vertical post. The hand grips are resiliently biased and may be moved conjointly or opposite to one another to provide arm exercise for a patient in the wheelchair. The gym also has leg supports on which resiliently biased foot rests may be moved conjointly or opposite to one another. The leg supports may be moved up and down or may be splayed laterally. | 2012-11-08 |
20120283077 | Sports Performance Enhancement System - A sport performance enhancing system includes a left glove, a right glove, a vest, a belt, a left shoe, a right shoe, and a plurality of resistance bands. The left glove and the right glove each consist at least one D-ring which provide the attachment of the left and right glove with the plurality of resistance bands. The vest also consist a plurality of vest rings that attaches with the plurality of resistance bands, attaching the left and right glove. A plurality of O-rings and a shoe D-ring in the left and right shoe are attached to the plurality of resistance band from one end, and the free end of the plurality of resistance bands attaches with a plurality of vertical rings and a plurality of horizontal rings which are positioned around the belt. | 2012-11-08 |
20120283078 | Exercise Table - An improved exercise table or reformer having increased adjustability and storage features. The starting point of the carriage or platform is adjustable to accommodate different sized users. An anchor bar mechanism is adjusted to correspond to carriage starting point, and limits rotation of the anchor bar with respect to the reformer and may be non-removable from the reformer frame. A foot bar assembly may be adjusted and placed in a storage position, allowing the foot bar to serve as a lift handle. The reformer's adjustability provides greater ease of storage. | 2012-11-08 |
20120283079 | Foldable Transportable Multiple Function Pilates Exercise Apparatus and Method - A multi-function Pilates exercise apparatus featuring a foldable frame, a counterbalance mechanism, a wheeled base, a rotatable pulley riser with a flexible pulley mount, gear changing apparatus and adjustable footbar. The frame is designed to fold into an upright position and to be rolled to a desired location. The pulley assemblies may be rotated and positioned below the carriage rails. The gear changing apparatus permits the user to adjust the carriage position with a single handed operation. The exercise system includes a reformer, a pole apparatus, and mat mode including a long/short box. | 2012-11-08 |
20120283080 | TRAINING STATION AND FITNESS STATION COMPRISING THE TRAINING STATION - The invention relates to a training station comprising a standing mat, a training device, a control unit, and a display unit. The standing mat comprises a sensor for generating a real-time standing signal depending on the position of at least one foot on the standing mat. The training device comprises a gripping means that is prestressed with a prestress, wherein said gripping means can be seized by the training person with one hand for training purposes and can be moved and/or held in a free manner against the prestress, and further comprises a position sensor for generating a real-time position signal depending on the position and/or the temporal position change of the gripping means relative to the standing mat. The control unit is equipped to receive the real-time standing signal and the real-time position signal, to define a target position range depending on the real-time standing signal, and to generate a real-time control signal depending on a comparison of the real-time position signal with the target position range to determine whether the current position and/or the current temporal position change of the gripping means are within the target position range. The display unit is equipped to receive the real-time control signal and make it available in a recognizable manner to the training person. | 2012-11-08 |
20120283081 | Multi-Translative Roll Assembly Having a One-way Clutching Surface - A roll assembly according to one example embodiment includes a rotatable input shaft. The input shaft is supported by a housing. At least one gear is mounted on the input shaft. A carrier frame is mounted on the input shaft and rotatable independent of the input shaft. A plurality of rolls is rotatably mounted about a periphery of the carrier frame. An axial direction of rotation of each roll is transverse to the rotational axis of the input shaft. Each roll has a contact surface and a gear face that is operatively coupled to the at least one gear. A first one-way clutching surface is positioned between one of (1) at least a portion of the rolls and the carrier frame, (2) the carrier frame and the input shaft, (3) the carrier frame and a portion of the housing, and (4) a combination thereof. | 2012-11-08 |
20120283082 | ROLLER FOR SEALED HEAD AND PROCESS FOR MANUFACTURING - The object of the present invention is a manufacturing process for a roller composed of a metal core covered by an elastomer coating and having an axis of symmetry, this process involving a first winding of a first non-vulcanized elastomer sheet onto the core, a vulcanization. | 2012-11-08 |
20120283083 | CUTTING STATION WITH COMPLETE CUTTING TOOL - The disclosure relates to a thermo-forming packaging machine with a cutting station including a complete cutting tool. The thermo-forming packaging machine is designed such that the complete cutting tool is extractable in a direction of production of the packaging machine. | 2012-11-08 |
20120283084 | COMPACT DUNNAGE STORAGE AND CONVERSION SYSTEM - A self-contained dunnage system includes a box sized to receive a supply of sheet stock material with minimal or no empty space when the box is closed. The box has one or more flaps that are movable between a generally planar closed position where the flaps cooperate to close the box and an inclined operating position displaced from the closed position. In the operating position, the ends of the flaps define a dispensing outlet spaced from an open side of the box defined by the side wall or walls of the box. The dispensing outlet is smaller than the open side of the box such that as the sheet material is pulled from the box and through the outlet, the inclined flaps act as a forming member that inwardly gathers the sheet material, causing it to crumple as it is withdrawn from the box. | 2012-11-08 |
20120283085 | CENTRIFUGAL APPARATUS FOR BIOCHEMICAL PROCESSES COMPRISING A GAS CHANNELING SYSTEM - An apparatus for performing a process having a step of centrifugation of a material contained in at least one test tube and a step of supplying a gas into the test tube. The apparatus has a centrifugation device provided with a rotor that is rotatably arranged about a central rotation axis, where at least one process housing is defined for at least one test tube, wherein at least one process housing is arranged at a peripheral position of the rotor with respect to the central rotation axis, a cover and a lock means for locking the rotor to the cover, said lock means comprising an elongated portion that is adapted to firmly engage with said rotor. The apparatus has a gas channeling means with a passageway defined in the lock member, the passageway conveying into the chamber a gas flow coming from an external source, and also a discharge passageway. | 2012-11-08 |
20120283086 | Metal colloid-colored glass ceramic and colorless glass convertible into same - A colorless transparent colloid-former-containing glass that is convertible into a colorless transparent glass ceramic or a metal colloid-colored glass ceramic via respective heat treatments contains a combination of one or more metal colloid formers and one or more redox partners. The metal colloid formers are compounds containing Au, Ag, As, Bi, Nb, Cu, Fe, Pd, Pt, Sb and/or Sn. The redox partners are compounds containing As, Ce, Fe, Mn, Sb, Sn and/or W, with the proviso that the redox partner must be different from the metal colloid former. | 2012-11-08 |
20120283087 | SYNTHETIC QUARTZ COMPOSITION AND PRODUCTION PROCESS THEREFOR - A synthetic quartz composition having improved tensile strength, compression strength and bending strength comprising up to 90% quartz stone, from 5 to 90% quartz powder, from 0.1 to 20% resin, from 1 to 25% fiber, from 0.1 to 5% coupling agent, from 0.1 to 5% curing agent, up to 70% glass chip, up to 70% mirror chip, up to 5% pigment, up to 5% shell chip, and up to 5% metal flake, by weight, may be produced in panels and molded shapes such as containers. | 2012-11-08 |
20120283088 | Mixed Oxide Catalysts Made of Hollow Shapes - The invention relates to mixed oxide catalysts made of hollow shapes for the catalytic gas phase oxidation of olefins, and to a method for producing the catalysts by applying them as a layer to a carrier made of organic material and removing said organic material. The reaction into aldehydes and carboxylic acids occurs by air or oxygen in the presence of inert gases in different quantity ratios, at elevated temperatures and pressure in the presence of said catalysts. | 2012-11-08 |
20120283089 | ZIEGLER-NATTA CATALYST FOR OLEFIN POLYMERIZATION - The present invention relates to a Ziegler-Natta catalyst, and more specifically to a Ziegler-Natta catalyst for olefin polymerization which may use a compound of Formula 3 as an internal electron donor to obtain polymers with high activity, wide molecular weight distribution and low content of fine particle. | 2012-11-08 |
20120283090 | Support Properties of Silica Supported Catalysts and Their Use in Olefin Metathesis - Silica supports having a surface area from about 250 m | 2012-11-08 |
20120283091 | CATALYST FOR CONVERTING EXHAUST GASES - A catalyst for purifying exhaust gases includes a substrate, and a catalytic layer. The catalytic layer includes a lower catalytic layer, a first upper catalytic layer, and a second upper catalytic layer. The lower catalytic layer being loaded with Pd and/or Pt is formed on the substrate. The first upper catalytic layer being loaded with Pd covers an upstream side of the lower catalytic layer, and exhibits a concentration of loaded Pd that falls in a range of from 4.5 to 12% by mass when the entirety of the first upper catalytic layer is taken as 100% by mass. The second upper catalytic layer being loaded with Rh covers a downstream side of the lower catalytic layer. | 2012-11-08 |
20120283092 | Stable Sub-Micron Titania Sols - The present invention is directed to compositions and processes for the production of stable, alkaline, high solids, low viscosity, low surface tension, low flammability, sub-micron titania sols that have minimal offensive odor and methods of their use. Compositions of the present invention include, for example, mixtures of strong and weak organic bases used as dispersants to stabilize the titania sols. The dispersant mixtures have been found to result in relatively high titania solids content, low surface tension, low viscosity suspensions that are low in flammability. Sols produced according to the present invention can be used, for example, in catalytic applications such as catalyst supports for diesel emission control, or in pollutant photocatalyst applications in which it is desirable to have the titania in sol form. | 2012-11-08 |
20120283093 | PERMEABLE MATRIX ALLOWING ADSORPTION AND CAPTURE OF CO2 BY MEANS OF CARBONIOUS MATERIAL AND A COOLING SYSTEM INDEPENDENT OF EXTERNAL ENERGY SOURCES - Disclosed is a material capable of adsorbing carbon dioxide which is obtainable by compressing a mixture of a carbonious material selected from fossil carbons and/or graphite and a solid binder consisting of a disaccharide or glucose in powder form. | 2012-11-08 |
20120283094 | PESTICIDAL BIS-ORGANOSULFUR COMPOUNDS - The present invention provides bis-organosulfur compounds of formulae (I) and (II) and compositions comprising the compounds that are effective against animal pests, including parasites. The compounds and compositions may be used for combating parasites in or on birds and mammals and for combating pests that damage crops, plants and plant propagation material. The invention also provides for an improved method for eradicating, controlling and preventing parasite infestation in birds and mammals. | 2012-11-08 |
20120283095 | PESTICIDAL MIXTURES - The present invention relates to synergistic mixtures comprising, as active components, one insecticidal compound I selected from the group consisting of carbamates; and one fungicidal compound II selected from the group of strobilurines in synergistic effective amounts. | 2012-11-08 |
20120283096 | AGENT FOR IMPROVING PLANT GROWTH, SEEDS, AND METHOD FOR IMPROVING PLANT GROWTH - The present invention relates to (i) a plant growth-improving agent containing a growth-improving component that increases a concentration of an oxoanion in an area around a plant, the oxoanion being heavier than a sulfate ion and containing four oxygen atoms, (ii) a seed to which such a plant growth-improving agent has been applied, and (iii) a plant growth-improving method including a cultivating step of growing a plant in the presence of such a growth-improving component. | 2012-11-08 |
20120283097 | PESTICIDAL COMPOSITIONS COMPRISING 4,5-DIHYDROXYINDAN-1-ONE - Provided are pesticidal compositions comprising 4,5-dihydroxyindan-1-one or derivatives thereof for protecting important crops against mites, fungi, and bacteria. The compositions may be manufactured by fractionating fungal extracts. | 2012-11-08 |
20120283098 | STABLE HIGH STRENGTH OIL-IN-WATER EMULSIONS - Novel high-strength herbicidal oil-in-water emulsions containing a water soluble salt of glyphosate and an oil soluble herbicide active ingredient show enhanced stability to oil phase coalescence and active ingredient crystallization by the use of specific surfactants and water immiscible organic solvents. | 2012-11-08 |
20120283099 | CONTROLLING PLANTHOPPERS - The invention disclosed in this document concerns controlling planthoppers. | 2012-11-08 |
20120283100 | CONTROLLING PLANTHOPPERS - The invention disclosed in this document concerns controlling planthoppers. | 2012-11-08 |
20120283101 | Plant Additives and Uses Thereof to Modulate the Synthesis of Membrane Glycerolipids in Planta - The present invention pertains to plant additives containing a molecule selected in a family of compounds, wherein said molecule can modulate some molecular markers and physiological modifications observed in cases of phosphate deficiency. The family of compounds comprises the molecule MC2 of formula (I) as well as analogues thereof. | 2012-11-08 |
20120283102 | FLOWERING INDUCER - The present invention provides a flowering inducer comprising any one of the following proteins (A)-(C). (A) a protein comprising the amino acid sequence represented by SEQ ID NO:2; (B) a protein comprising an amino acid sequence having deletion, substitution and/or addition of one or several amino acids in the amino acid sequence represented by SEQ ID NO:2 and having a flowering-inducing activity; and (C) a protein comprising an amino acid sequence having an identity of 60% or more with the amino acid sequence represented by SEQ ID NO:2 and having a flowering-inducing activity. This flowering inducer can be administered into a plant body from outside. | 2012-11-08 |
20120283103 | Amides, use of Amides as Solvents for Organic Compounds, Compositions and Emulsions Containing Amides, and Method for Treating a Plant - The present invention relates in general to the use of amides of the following general formula (I) wherein R | 2012-11-08 |
20120283104 | Microcapsules containing pesticide and having polyvinyl monomers as cross-linking agents - The present invention relates to microcapsules comprising a pesticide-containing capsule core and a capsule wall, and to a process for the preparation of these microcapsules. Furthermore, the invention relates to an agrochemical formulation comprising the microcapsules, and to the use of the microcapsules for controlling phytopathogenic fungi and/or undesired plant growth and/or undesired insect or mite infestation and/or for regulating the growth of plants. | 2012-11-08 |
20120283105 | Superconducting Strip Having Metal Coating Layer and Method Of Manufacturing the Same - A rolled superconducting article includes: a cylindrical bobbin having a post in a cylindrical shape; a superconducting strip wound on the cylindrical bobbin in a rolled shape with a predetermined tension applied, wherein the superconducting strip is formed of a superconducting thin film, which is coated with a metal coating layer on a facing surface of the superconducting thin film, and a stabilizing substrate wound on the superconducting strip, wherein the stabilizing substrate is coated with a metal coating layer on a facing surface of the stabilizing substrate; an anti-bonding substrate wound on an outer surface of the stabilizing substrate with a predetermined tension applied; wherein the superconducting thin film is thermally adhered to the stabilizing substrate by heat-treating the rolled superconducting strip with the anti-bonding substrate wound therearound. | 2012-11-08 |
20120283106 | METHODS TO DETECT AND QUANTIFY RNA - Improved methods to quantitate RNA in biological or other analytical samples employ extended RNAs containing adaptors at the 5′ end and polyA sequences coupled to a tag at the 3′ end. The invention method is particularly useful in quantitating microRNAs as primers can be used that need not complement the non-conserved 3′ ends of these molecules. | 2012-11-08 |
20120283107 | Charge Perturbation Detection Method for DNA and Other Molecules - Methods for direct detection of chemical reactions are provided. Electric charge perturbations of the local environment during enzyme-catalyzed reactions are sensed by an electrode system with an immobilized target molecule. The charge perturbation caused by the polymerase reaction can uniquely identify a DNA sequence. The polymerization process generates local perturbations of charge in the solution near the electrode surface and induces a charge in a polarazible gold electrode. This event is detected as a transient current by a voltage clamp amplifier. Detection of single nucleotides in a sequence can be determined by dispensing individual dNTPs to the electrode solution and detecting the charge perturbations. Alternatively, multiple bases can be determined at the same time using a mix of all dNTPs with subsequent analysis of the resulting signal. This technique may be adapted to other reaction determinations, such as enzymatic reactions, other electrode configurations, and other amplifying circuits. | 2012-11-08 |
20120283108 | METHOD FOR PHASED GENOTYPING OF A DIPLOID GENOME - A method of sample analysis is provided. In certain embodiments the method comprises: a) obtaining from a diploid individual a chromosomal sample that comprises maternally-derived chromosomes and homologous paternally-derived chromosomes; b) determining the parent of origin of a first chromosome of the sample by detecting a parent-specific copy number variation relative to a second chromosome that is homologous to the first chromosome; c) isolating the first chromosome; and d) genotyping the first chromosome. | 2012-11-08 |
20120283109 | METHOD OF ANALYZING TARGET NUCLEIC ACID OF BIOLOGICAL SAMPLES - This invention provides a method of analyzing target nucleic acids of biological samples for multiplex nucleic acid analysis of disease associated genetic changes of biological samples in biomedical research and clinical diagnostics. | 2012-11-08 |
20120283110 | METHODS FOR RETRIEVAL OF SEQUENCE-VERIFIED DNA CONSTRUCTS - In some embodiments, methods of recovering a sequence-verified target nucleic acid are provided. In some embodiments, such methods may include tagging each member of a nucleic acid library with a set of adaptor sequences; sequencing the tagged members of the nucleic acid library; and recovering the sequence-verified target nucleic acid from the tagged and sequenced members of the nucleic acid library using a dial-out selection method. In certain embodiments, the members of the nucleic acid library may be tagged with a second set of adaptor sequences. | 2012-11-08 |
20120283111 | Bacterial mRNA screen strategy for novel pesticide-encoding nucleic acid molecule discovery - Methods are provided for isolating and identifying novel pesticide-encoding nucleic acid molecules from bacterial strains identified as having a pesticidal polypeptide. The methods involve selecting a bacterial strain having or suspected of having at least one pesticide-encoding plasmid, curing the at least one pesticide-encoding plasmid from the bacterial strain and performing a subtractive hybridization to obtain plasmid mRNA encoding the pesticidal polypeptide. The plasmid mRNA can be used to make a cDNA library from which the pesticidal polypeptide can be isolated and subsequently identified. | 2012-11-08 |
20120283112 | Systems and Methods for Identifying Cosmetic Agents for Skin Care Compositions - Provided are methods and systems for determining functional relationships between a cosmetic agent and a skin tissue condition of interest. Also provided are methods and systems for identifying cosmetic agents that affect a skin aging tissue condition, as well as the use of agents identified by such methods and systems for the preparation of cosmetic compositions, personal care products, or both. | 2012-11-08 |
20120283113 | Compositions and methods for antibody and ligand identification - Embodiments disclosed herein relate to methodology, and kits thereof for identifying particular disease-associated antibodies partially based on comparative binding to a mimotope array. Isolation of identified disease-associated antibodies and uses thereof are also described. | 2012-11-08 |
20120283114 | NEW DIAGNOSTIC TOOLS FOR ALZHEIMER DISEASE - The present invention relates to development, validation and application of new sets of biomarkers for diagnosis of Alzheimer's disease (AD) and related disorders including early diagnosis of MCI and early prodrome of AD, identification of disease sub types, prediction of their response to disease management procedures, drugs and their combinations and for monitoring response for these treatment, including validation of biomarkers for clinical trials. | 2012-11-08 |
20120283115 | SEROMIC ANALYSIS OF OVARIAN CANCER - The invention relates to the discovery of cancer antigens associated with ovarian cancer. In further aspects, the invention relates to methods, compositions and kits for the diagnosis and treatment of cancer, particularly ovarian and pancreatic cancers. | 2012-11-08 |
20120283116 | Mutant Sodium Channel Nav1.7 and Methods Related Thereto - Described are mutant Na | 2012-11-08 |
20120283117 | DETERMINATION OF EOSINOPHILIC ESOPHAGITIS - Eosinophilic esophagitis (EE), an emerging disorder with poorly understood pathogenesis, was examined. Esophageal tissue was analyzed by a genome wide microarray expression analysis. EE patients had a transcript signature involving 1% of the genome that was conserved across gender, age, and atopic status, and was distinct from that associated with chronic esophagitis (CE). The eosinophil specific chemokine eotaxin-3 was the top induced gene compared with normal controls. Levels C of eotaxin-3 mRNA and protein correlated with disease severity. A single nucleotide polymorphism in the human eotaxin-3 gene conferred susceptibility to disease. Mice deficient in the eotaxin-3 receptor (CCR-3) were protected from experimental EE. Eotaxin-3 was identified as a specific effector molecule, biomarker, and genetic risk factor for EE, and distinguished EE from CE. | 2012-11-08 |
20120283118 | METHODS FOR DETECTING MYCOBACTERIUM TUBERCULOSIS ANTIGENS - Method for detecting | 2012-11-08 |
20120283119 | POTENTIOMETRIC DNA MICROARRAY, PROCESS FOR PRODUCING THE SAME AND METHOD OF ANALYZING NUCLEIC ACID - A DNA microarray system whereby measurement can be performed at a low running cost, a low price and yet a high accuracy. A nucleic acid probe ( | 2012-11-08 |
20120283120 | SCREENING METHOD - The present invention provides a novel variant androgen receptor (ARaiv) lacking ligand binding domain, a nucleic acid encoding the same and use thereof. That is, the present invention provides a method of screening for a substance for the prophylaxis or treatment of cancer, which includes contacting an ARaiv protein or ARaiv-producing cell with a test compound, measuring the activity of ARaiv (e.g., transcription regulating action of androgen responsive gene) or expression level thereof, and selecting a compound that suppresses the activity or expression level. | 2012-11-08 |
20120283121 | Quantification of IR-A and IR-B for Tumor Classification - Without limitation, this disclosure relates to compositions and methods for detecting and quantifying the expression of insulin receptor isoform A (IR-A) and/or insulin receptor isoform B (IR-B) in a tissue sample. The disclosure also relates to methods of diagnosis and classification based at least in part upon detecting and quantifying the expression of insulin receptor isoform A (IR-A) and/or insulin B (IR-B) in a tissue sample. Methods of treating a subject based upon such a classification are among additional aspects of the disclosure presented herein. | 2012-11-08 |
20120283122 | ANALYTE QUANTIFICATION MULTIPLEX MICROARRAYS COMBINING INTERNAL AND EXTERNAL CALIBRATION - The present invention relates to multiplex microarrays and methods for the quantification of analytes. In particular, the invention relates to improved methods which standardize a target analyte concentration in a test sample against a reference standardization curve derived from validated, approved and recognized reference standards for the target analyte of known concentrations. The present invention also relates to methods and checks for simultaneous measurement of confidence confirming normalization standards and controls. | 2012-11-08 |
20120283123 | Biomarkers for the Diagnosis of Kidney Graft Rejection - Methods are provided for determining a transplant category of a subject having a kidney graft. In practicing one aspect of the subject methods, the peptide signature of a non-invasive sample derived from the transplant subject (e.g., a urine sample) is used to determine the subject's transplant category (e.g., acute allograft rejection (AR), stable allograft (STA), BK virus nephropathy (BK), and the like). In other embodiments, a gene expression signature from a biopsy sample from the subject (e.g., mRNA level) is used to determine the subject's transplant category. In certain embodiments both a peptide signature and a gene expression signature are used. Also provided are compositions, systems, kits and computer program products that find use in practicing the subject methods. | 2012-11-08 |
20120283124 | Cell Surface Marker Expression in Hematopoietic Stem Cells and Progenitors for the Diagnosis, Prognosis, and Treatment of Myelodysplastic Syndromes - Myelodysplastic syndromes are staged by analysis of the presence of hematopoietic stem and/or progenitor cells, particularly progenitor cells dedicated to the myeloid lineage and hematopoietic stem cells. | 2012-11-08 |
20120283125 | Ovarian Markers of Oocyte Competency and Uses Thereof - The present invention relates to the competence of oocytes to fertilization, uterine implantation and development into a living being. The invention describes ovarian markers whose expression is predicative of oocyte competency that are detected and/or measured in follicular fluid, cumulus cells and/or follicular cells of a mammal. Also described are methods for evaluating competence of mammalian oocytes, methods for selecting a mammalian oocyte for assisted reproduction (AR), and screening methods for identifying stimulatory or inhibitory compounds to mammalian oocyte competence. | 2012-11-08 |
20120283126 | HUMAN FERTILITY TEST USING DPY19L2 - The present patent application concerns a method for diagnosing infertility related to the DPY19L2 protein, in a male human subject, and a method for treating said subject with a view to restoring fertility. The present invention also concerns the use of molecules inhibiting the action of the DPY19L2 polypeptide in a wild-type carrier male subject, for example of anti-DPY19L2 interfering nucleic acid type selectively inhibiting the expression of the DPY19L2 polypeptide. | 2012-11-08 |
20120283127 | DIAGNOSTIC METHOD FOR ALZHEIMER'S DISEASE - The present invention provides an ex vivo method for aiding the diagnosis of Alzheimer's disease in a patient, the method comprising the steps of determining the level of expression of at least four platelet proteins in a platelet sample from the patient selected from monoamine oxidase-B, coagulation factor Xllla, total tropomyosin (a and 13), WD-repeat protein 1 and apolipoprotein E4; and comparing the result of (i) to a control value, wherein a result higher than the control value is indicative of Alzheimer's disease. Preferably, the method of the invention further comprises determining the level of expression of wild-type GSTO-1 or mutant GSTO-1. | 2012-11-08 |
20120283128 | METHODS AND COMPOSITIONS FOR DIAGNOSIS AND PROGNOSIS OF RENAL INJURY AND RENAL FAILURE - The present invention relates to methods and compositions for monitoring, diagnosis, prognosis, and determination of treatment regimens in subjects suffering from or suspected of having a renal injury. In particular, the invention relates to using a plurality of assays, one or more of which is configured to detect a kidney injury marker selected from the group consisting of Hyaluronic acid, Immunoglobulin A, Immunoglobulin G1, Immunoglobulin G2, Insulin-like growth factor-binding protein 7, Alpha-1 antitrypsin, Serum amyloid P component, Metalloproteinase inhibitor 2, Hepatocyte growth factor, Intercellular adhesion molecule 1, Beta-2-glycoprotein 1, Interleukin-1 beta, Neutrophil Elastase, Tumor necrosis factor receptor superfamily member 11B, Interleukin-11, Cathepsin D, C—C motif chemokine 24, C—X—C motif chemokine 6, C—C motif chemokine 13, C—X—C motif chemokines -1, -2, and -3, Matrilysin, Interleukin-2 receptor alpha chain, Insulin-like growth factor-binding protein 3, and Macrophage colony-stimulating factor 1 as diagnostic and prognostic biomarkers in renal injuries. | 2012-11-08 |
20120283129 | COMPOSITIONS AND METHODS FOR DIAGNOSING AND TREATING KIDNEY DISORDERS IN A CANINE - The present invention provides methods for: diagnosing of, devising and monitoring a treatment plan for, and monitoring the status of a kidney disorder characterized by an abnormal loss of renal function, renal failure, reduced glomerular filtration rate or glomerulonephritis, in a canine, wherein the kidney disorder is detectable by utilizing at least one relevant biomarker isolated and measured from a biological test sample taken from such canine. The invention additionally relates to compositions, reagents and kits for carrying out the specified methods. | 2012-11-08 |
20120283130 | METHOD FOR SCREENING INDUCED PLURIPOTENT STEM CELLS - The present invention relates to miRNA or genes expressed in induced pluripotent stem cells, and a method for screening for induced pluripotent stem cells having functions equivalent to those of embryonic stem cells by confirming methylation of specific gene regions of induced pluripotent stem cells. | 2012-11-08 |
20120283131 | HIV TYPE AND SUBTYPE DETECTION - The present invention relates to the detection of HIV by amplification and PCR-based methods. | 2012-11-08 |
20120283132 | MOLECULAR IN VITRO DIAGNOSIS OF BREAST CANCER - A method for determining the benign or malignant state of a breast tumor in a biological sample is presented. The benign or malignant state is determined by measuring the variation of expression of twelve genes and at least one variant of each of the twelve genes when the variants exist, using a combination of 50 polynucleotide probe sets. An expression profile of the sample is then compared with reference expression profiles of control benign and malignant breast tissues. The probe sets can be arranged in a microarray. | 2012-11-08 |
20120283133 | MICROFLUIDIC SELECTION OF LIBRARY ELEMENTS - A microfluidic device includes a chip; a flow channel being disposed in the chip; the flow channel being in communication with an entry port and an exit port; the flow channel being operative to permit the flow of a library from the entry port to the exit port; a substrate; the substrate being disposed upon the chip; the substrate being operative to act as an upper wall for the flow channels; and a plurality of receptors; the plurality of receptors being disposed on the substrate; the plurality of receptors being operative to interact with an element from the library. | 2012-11-08 |
20120283134 | Method for Identifying Lineage-Related Antibodies - In certain embodiments, the method may comprise: a) obtaining the antibody sequences from a population of B cells; b) grouping the antibody sequences to provide a plurality of groups of lineage-related antibodies; c) testing a single antibody from each of the groups in a bioassay and, after the first antibody has been identified, d) testing further antibodies that are in the same group as the first antibody in a second bioassay. In another embodiment, the method may comprise: a) testing a plurality of antibodies obtained from a first portion of an antibody producing organ of an animal; b) obtaining the sequence of a first identified antibody; c) obtaining from a second portion of said antibody producing organ the sequences of further antibodies that are related by lineage to said first antibody; and, c) testing the further antibodies in a second bioassay. | 2012-11-08 |
20120283135 | PRIMERS AND PROBES FOR DETECTION AND DISCRIMINATION OF TYPES AND SUBTYPES OF INFLUENZA VIRUSES - Methods of detecting influenza, including differentiating between type and subtype are disclosed, for example to detect, type, and/or subtype an influenza infection. A sample suspected of containing a nucleic acid of an influenza virus, is screened for the presence or absence of that nucleic acid. The presence of the influenza virus nucleic acid indicates the presence of influenza virus. Determining whether the influenza virus nucleic acid is present in the sample can be accomplished by detecting hybridization between an influenza specific probe, influenza type specific probe, and/or subtype specific probe and an influenza nucleic acid. Probes and primers for the detection, typing and/or subtyping of influenza virus are also disclosed. Kits and arrays that contain the disclosed probes and/or primers also are disclosed. | 2012-11-08 |
20120283136 | COMPOSITIONS AND METHODS FOR THE RAPID BIOSYNTHESIS AND IN VIVO SCREENING OF BIOLOGICALLY RELEVANT PEPTIDES - This invention provides new combinatorial approaches for the biosynthesis and screening of cyclic peptides inside living cells. These novel approaches are useful for finding biologically relevant molecules, e.g., those able to inhibit the cytotoxicity of Anthrax Edema Factor. Key to this ‘living combinatorial’ approach is the use of a living cell as a micro-chemical factory for both synthesis and screening of potential inhibitors for a given molecular recognition event. | 2012-11-08 |
20120283137 | MASS LABELS - A reactive mass label for labelling a biological molecule for detection by mass spectrometry, which label comprises a reactive functionality for labelling thiol groups or carbonyl groups. Also provided is a reactive mass label for labelling a biological molecule for detection by mass spectrometry, wherein the mass label comprises the following structure: | 2012-11-08 |
20120283138 | System and device for reporting a result of an evaluation of a sample after queuing the result for transmission - A system or device includes an evaluation module for automatically evaluating, remotely from a health care facility, a biological sample acquired from a subject for a presence or an absence of at least one pathogen in the biological sample; an electronic memory for queuing a first result of the evaluation for transmission to an off-site entity; and a reporting module for reporting a second result of the evaluation to the subject after queuing the first result of the evaluation for transmission. | 2012-11-08 |
20120283139 | METHOD OF DESIGNING ADDRESSABLE ARRAY SUITABLE FOR DETECTION OF NUCLEIC ACID SEQUENCE DIFFERENCES USING LIGASE DETECTION REACTION - The present invention is directed to a method of designing a plurality of capture oligonucleotide probes for use on a support to which complementary oligonucleotide probes will hybridize with little mismatch, where the plural capture oligonucleotide probes have melting temperatures within a narrow range. The first step of the method involves providing a first set of a plurality of tetramers of four nucleotides linked together, where (1) each tetramer within the set differs from all other tetramers in the set by at least two nucleotide bases, (2) no two tetramers within a set are complementary to one another, (3) no tetramers within a set are palindromic or dinucleotide repeats, and (4) no tetramer within a set has one or less or three or more G or C nucleotides. Groups of 2 to 4 of the tetramers from the first set are linked together to form a collection of multimer units. From the collection of multimer units, all multimer units formed from the same tetramer and all multimer units having a melting temperature in ° C. of less than 4 times the number of tetramers forming a multimer unit are removed to form a modified collection of multimer units. The modified collection of multimer units is arranged in a list in order of melting temperature. The order of the modified collection of multimer units is randomized in 2° C. increments of melting temperature. Alternating multimer units in the list are then divided into first and second subcollections, each arranged in order of melting temperature. After the order of the second subcollection is inverted, the first collection is linked in order to the inverted second collection to form a collection of double multimer units. From the collection of double multimer units, those units (1) having a melting temperature in ° C. less than 11 times the number of tetramers and more than 15 times the number of tetramers, (2) double multimer units with the same 3 tetramers linked together, and (3) double multimer units with the same 4 tetramers linked together with or without interruption are removed, to form a modified collection of double multimer units. The modified collection of double multimers can be immobilized on a support and used to capture, by hybridization, the products of a ligation detection reaction. As a result, the output of a ligation detection reaction, which is useful in detecting single-base changes, insertions, deletions, or translocations in a plurality of target nucleotide sequences, can be formatted on a support. | 2012-11-08 |
20120283140 | Microfluidic Devices and Methods for Gene Synthesis - Certain aspects of the present invention provide devices and methods for preparing oligonucleotides and for assembling nucleic acid molecules using microfluidic devices. | 2012-11-08 |
20120283141 | ENZYME-CATALYZED METAL DEPOSITION FOR THE ENHANCED DETECTION OF ANALYTES OF INTEREST - The invention is directed to enhanced methods for detecting an analyte of interest in situ, by immunoassay, or by hybridization comprising binding an enzyme-labeled conjugate molecule to an analyte of interest in the presence of a redox-inactive reductive species and a soluble metal ion. The enzyme catalyzes the conversion of the inactive reductive species to an active reducing agent, which in turn reduces the metal ion to a metal atom thereby providing an enhanced means of detecting the analyte via metal deposition. | 2012-11-08 |
20120283142 | siRNA Targeting Amyloid Beta (A4) Precursor Protein (APP) - Efficient sequence specific gene silencing is possible through the use of siRNA technology. By selecting particular siRNAs by rational design, one can maximize the generation of an effective gene silencing reagent, as well as methods for silencing genes. Methods, compositions, and kits generated through rational design of siRNAs are disclosed including those directed to nucleotide sequences for APP. | 2012-11-08 |
20120283143 | Compositions and methods for antibody and ligand identification - Embodiments disclosed herein relate to methodology, and kits thereof for identifying particular disease-associated antibodies partially based on comparative binding to a mimotope array. Isolation of identified disease-associated antibodies and uses thereof are also described. | 2012-11-08 |
20120283144 | Ligation Enhancement - Compositions and methods are provided for enhancing enzymatic ligation between nucleic acid fragments that relies on one or more small molecule enhancers having a size of less than 1000 daltons. For example, enhancement of ligation efficiencies are observed for double-stranded nucleic acid fragments that are blunt-ended, have a single nucleotide overhang at the ligation end, or have staggered ends compared to ligation under similar conditions in the absence of the one or more small molecule ligation enhancer. The use of small molecule enhancers for ligating nucleic acids results in an increased number of transformed host cells after transformation with the ligated molecules. This enhancement can be observed with chemically transformed host cells and with host cells transformed by electroporation. | 2012-11-08 |
20120283145 | Methods of Making Di-Tagged DNA Libraries from DNA or RNA Using Double-tagged Oligonucleotides - Disclosed are methods, compositions and kits related to making double-tagged DNA libraries from RNA/DNA samples. A double-tagged oligonucleotide (DTO) is employed to efficiently add two different tags to ends of DNAs to make a double-tagged DNA libraries. Also disclosed are methods to make mate pair libraries using the double-tagged oligonucleotide, and methods to make double-tagged single stranded DNA. The double-tagged DNA libraries of the invention are ready to be used on next generation sequencing machines. | 2012-11-08 |
20120283146 | CHEMICALLY-SENSITIVE SENSOR ARRAY CALIBRATION CIRCUITRY - Methods and apparatus relating to very large scale FET arrays for analyte measurements. ChemFET (e.g., ISFET) arrays may be fabricated using conventional CMOS processing techniques based on improved FET pixel and array designs that increase measurement sensitivity and accuracy, and at the same time facilitate significantly small pixel sizes and dense arrays. Improved array control techniques provide for rapid data acquisition from large and dense arrays. Such arrays may be employed to detect a presence and/or concentration changes of various analyte types in a wide variety of chemical and/or biological processes. In one example, chemFET arrays facilitate DNA sequencing techniques based on monitoring changes in hydrogen ion concentration (pH), changes in other analyte concentration, and/or binding events associated with chemical processes relating to DNA synthesis. | 2012-11-08 |
20120283147 | LOW DOSAGE POLYMERIC NAPHTHENATE INHIBITORS - Polymeric naphthenate inhibitors are delivered into production fluids to contact mixtures of oil and water, such as in a hydrocarbon producing formation, production equipment, or processing systems. These polymeric naphthenate inhibitors exhibit surface-active properties causing the inhibitors to self-associate at oil-water interfaces and inhibit interactions between organic acids in the oil and cations or cation complexes in water. The large surface area makes these polymers persistent and effective at low concentrations. These compounds also inhibit aggregation of organic acid carboxylate salts that form when pH and pressure conditions are amenable to organic acid ionization. Preferred inhibitors do not form emulsions due to the formation of unstable mixed interface structures that result in coalescence of dispersed droplets. Naphthenate inhibitor dosages less than 100 ppm can effectively inhibit naphthenate salts or other organic acid salts that can form precipitates or emulsions during crude oil production or processing. | 2012-11-08 |
20120283148 | Methods and Compositions for Hydrocarbon-Based Crosslinking Additives with Non-Detectable BTEX Levels - Disclosed is a hydrocarbon-based concentrate composition for crosslinking polysaccharide polymers in an aqueous-based fluid, such as a fracturing fluid, wherein the hydrocarbon-based composition has no or substantially no detectable levels of benzene, toluene, ethylbenzene, and/or m-, o-, or p-xylenes (BTEX). Preferred polysaccharide polymers are galactomannan gums or derivatives thereof. The concentrate comprises an oleaginous solution, such as a hydrocarbon distillate, a crosslinking agent for crosslinking the polysaccharide polymer, preferably a sparingly soluble alkali metal or alkali metal alkaline earth metal borate, and a stabilizing/suspension agent, preferably a clay mineral selected from the group consisting of smectite clays. The concentrate may, optionally, contain a deflocculant and/or an anti-syneresis additive. | 2012-11-08 |
20120283149 | Compositions and Methods for Treatment of Well Bore Tar - Of the many compositions and methods provided herein, one example composition includes a treatment fluid comprising: an aqueous fluid; and a tar stabilizing polymer comprising at least one polymer selected from the group consisting of a styrene polymer, an acrylate polymer, a styrene-acrylate polymer, and any combination thereof. | 2012-11-08 |
20120283150 | Polymeric Additives for Enhancement of Treatment Fluids Comprising Viscoelastic Surfactants and Methods of Use - A subterranean treatment additive comprising a viscoelastic surfactant and an amphiphilic polymer. Wherein the amphiphilic polymer comprises a hydrophobic component, and a hydrophilic component, the hydrophilic component itself comprising at least 15 monomer units. The subterranean treatment additive may be used as part of a treatment fluid with an aqueous base fluid that may be a brine. | 2012-11-08 |
20120283151 | BIODEGRADABLE LUBRICATING COMPOSITION AND USE THEREOF IN A DRILLING FLUID, IN PARTICULAR FOR VERY DEEP RESERVOIRS - The present disclosure relates to a biodegradable lubricant composition, notably intended to be incorporated as an oil phase with high lubricating power in a drilling fluid or mud. This composition may be in a drilling fluid or as a fluid for fracture of underground formations. These muds or fluids contained in the composition of the present disclosure are particularly suitable for very deep drillings, offshore in deep water and/or sidetracked drillings or with a long shift. | 2012-11-08 |
20120283152 | WATER-BASED FLUID LOSS ADDITIVE CONTAINING AN AMPHIPHILIC DISPERSANT FOR USE IN A WELL - A well treatment composition comprises: an aqueous liquid; a fluid loss additive, wherein the fluid loss additive comprises a high molecular weight, water-swellable polymer; and an amphiphilic dispersant, wherein the well treatment composition has an activity of at least 10%. A method of cementing in a subterranean formation comprises: introducing a cement composition into the subterranean formation, the cement composition comprising: (i) cement; (ii) water; and (iii) the well treatment composition; and allowing the cement composition to set. | 2012-11-08 |
20120283153 | COATED AND CURED PROPPANTS - Solid proppants are coated with a coating that exhibits the handling characteristics of a precured coating while also exhibiting the ability to form particle-to-particle bonds at the elevated temperatures and pressures within a wellbore. The coating includes a substantially homogeneous mixture of (i) at least one isocyanate component having at least 2 isocyanate groups, and (ii) a curing agent. The coating process can be performed with short cycle times, e.g., less than about 4 minutes, and still produce a dry, free-flowing, coated proppant that exhibits low dust characteristics during pneumatic handling but also proppant consolidation downhole for reduced washout and good conductivity. | 2012-11-08 |
20120283154 | Saponified Fatty Acids as Breakers for Viscoelastic Surfactant-Gelled Fluids - Fluids viscosified with viscoelastic surfactants (VESs) may have their viscosities affected (increased or reduced, e.g. gels broken) by the indirect or direct action of a composition that contains at least one fatty acid that has been affected, modified or reacted with an alkali metal base, an alkali earth metal base, ammonium base, and/or organic base compound, optionally with an alkali metal halide salt, an alkali earth metal halide salt, and/or an ammonium halide salt. The composition containing the resulting saponification product is believed to either act as a co-surfactant with the VES itself to increase viscosity and/or possibly by disaggregating or otherwise affecting the micellar structure of the VES-gelled fluid. In a specific, non-limiting instance, a brine fluid gelled with an amine oxide surfactant may have its viscosity broken with a composition containing naturally-occurring fatty acids in canola oil or corn oil affected with CaOH, MgOH, NaOH and the like. | 2012-11-08 |
20120283155 | Controlling Coal Fines in Coal Bed Operations - The migration of coal fines within a bed is reduced, inhibited or constrained by contacting the fines with nanoparticles, such as magnesium oxide crystals having an average particle size of about 30 nm. These nanoparticles may coat a proppant during the fracturing of a subterranean formation to produce methane from a coal bed therein. The nanoparticles may also treat a proppant pack in a fractured coal bed. The nanoparticles cause the coal fines to thus bind to or associate with the proppants. Thus, most of the coal fines entering fractures away from the near-wellbore region will be restrained or controlled near their origin or source and the production of methane at a desired level will be maintained much longer than a similar situation than where the nanoparticles are not used. | 2012-11-08 |
20120283156 | FUNCTIONALIZED MONOMERS - This invention relates to functionalized monomers which are reacted with an enophilic reagent (e.g., maleic anhydride) to form an enophilic reagent modified functionalized monomer. The enophilic reagent modified functionalized monomer may be further reacted with one or more additional reagents (e.g., oxygen-containing reagents, nitrogen-containing reagents, metals or metal compounds). The invention relates to base oils which may comprise functional base oils. The invention relates to lubricants, functional fluids, fuels, dispersants, detergents and functional compositions (e.g., cleaning solutions, food products, etc.). | 2012-11-08 |
20120283157 | LUBRICANT COMPOSITION - The lubricating oil composition of the invention comprises a lubricating base oil with a 100° C. kinematic viscosity of 1-20 mm | 2012-11-08 |
20120283158 | Stabilized Blends Containing Friction Modifiers - The present invention relates to functional fluid compositions containing friction modifiers, and specifically stable compositions containing friction modifiers with limited solubility in and/or limited compatibility with the functional fluids with which they are used. In particular the present invention deals with functional fluids used in internal combustion engines, such as engine oils, and friction modifiers that contain one or more amide functional groups, where the friction modifier is present in the functional fluid composition at levels that would otherwise cause the composition to be unstable and/or hazy. | 2012-11-08 |
20120283159 | LUBRICANT COMPOSITION - The lubricating oil composition of the invention comprises a lubricating base oil with a 100° C. kinematic viscosity of 1-20 mm | 2012-11-08 |
20120283160 | SYNTHESIS OF BIOLUBRICANT ESTERS FROM UNSATURATED FATTY ACID DERIVATIVES - The present invention is generally directed to diester-based lubricant compositions comprising one or more isomeric mixtures of diester species. The present invention is also directed to methods of making these and other similar lubricant compositions. In some embodiments, the methods for making such diester-based lubricants utilize a biomass precursor material from which mono-unsaturated free lipid species can be provided or otherwise generated, wherein such mono-unsaturated free lipid species are converted to isomeric diol species en route to the synthesis of diester species for use as/in the diester-based lubricant compositions. | 2012-11-08 |
20120283161 | LUBRICATING OIL COMPOSITION - Disclosed is a lubricating oil composition which includes a diester-based base oil having an asymmetric structure in which the number of carbons of the alkyl chain bound to one ester group with respect to a central atom is two more than that of the alkyl group bound to the other ester group, and which has low viscosity and a comparatively small amount of evaporation at high temperature. When this composition is used for a motor of a small hard disk, power consumption can be reduced and stability at high temperature can be enhanced. | 2012-11-08 |
20120283162 | BASE OIL FOR COOLING OF DEVICE, DEVICE-COOLING OIL CONTAINING THE BASE OIL, DEVICE TO BE COOLED BY THE COOLING OIL, AND DEVICE COOLING METHOD USING THE COOLING OIL - A device-cooling base oil includes 30 mass % of at least one of an oleyl ester (e.g., oleate and oleyl alcohol ester) and oleyl ether. The oleyl ester and the oleyl ether each have 23 or more of a total number of a terminal methyl group, a methylene group and an ether group in a main chain and 1 or less of a total number of a methyl branch and an ethyl branch. The base oil has a kinematic viscosity at 40 degrees C. in a range of 4 mm | 2012-11-08 |
20120283163 | COPPER CLEANING AND PROTECTION FORMULATIONS - A cleaning composition and process for cleaning post-chemical mechanical polishing (CMP) residue and contaminants from a microelectronic device having said residue and contaminants thereon. The cleaning compositions include novel corrosion inhibitors. The composition achieves highly efficacious cleaning of the post-CMP residue and contaminant material from the surface of the microelectronic device without compromising the low-k dielectric material or the copper interconnect material. | 2012-11-08 |
20120283164 | Alpha-Amylase Mutants - The invention relates to a novel Termamyl-like alpha-amylase, and Termamyl-like alpha-amylases comprising mutations in two, three, four, five or six regions/positions. The variants have increased thermostability at acidic pH and/or at low Ca | 2012-11-08 |
20120283165 | NEUTRAL OR ALKALINE MEDIUM CHAIN PEROXYCARBOXYLIC ACID COMPOSITIONS AND METHODS EMPLOYING THEM - The present invention relates to medium chain peroxycarboxylic acid compositions of neutral or alkaline pH, to methods of making these compositions, and to methods employing these compositions. The methods include methods of cleaning. The compositions include cleaning compositions. | 2012-11-08 |
20120283166 | PEPTIDE PRODRUGS - Provided herein are a novel class of oligopeptides and prodrugs that include amino acid sequences containing cleavage sites for fibroblast activation protein (FAP). Also provided herein are methods of treating FAP related disorders, including cancer. | 2012-11-08 |
20120283167 | EV576 FOR USE IN THE TREATMENT OF VIRAL INFECTIONS OF THE RESPIRATORY TRACT - The present invention relates to methods of treating and preventing the inflammatory effects of viral infection of the upper and lower respiratory tracts, including infection by SARS coronovirus (SARS), pandemic Influenza A H5N1 (avian influenza) and pandemic influenza A H1N1 (swine 'flu). | 2012-11-08 |