44th week of 2010 patent applcation highlights part 49 |
Patent application number | Title | Published |
20100280146 | Forming clear, wettable silicone hydrogel articles without surface treatments - The present invention is a composition, which may be used to form contact lenses, comprising at least one silicone containing component, at least one hydrophilic component, at least one high molecular weight hydrophilic polymer and at least one diluent with an alpha value of about 0.5 to about 1 and a Hansen solubility parameter of less than about 10. | 2010-11-04 |
20100280147 | High refractive index interpenetrating networks for ophthalmic applications - Ophthalmic devices are provided based on an interpenetrating (IPN) double network hydrogel of a first network physically entangled with a second network. The first network is an entangled network of self-linked hydrophilic telechelic macromonomers and hydrophobic moieties. The second network is a hydrophilic network of crosslinked polyacrylic acid. The IPN double network hydrogels including the hydrophobic moieties are characterized by being optically clear and having refractive indices above 1.34. | 2010-11-04 |
20100280148 | ANCHORED POLYSILOXANE-MODIFIED POLYURETHANE COATINGS AND USES THEREOF - A polymeric material, prepared by reacting a mixture comprising a polyorganosiloxane having one or more isocyanate-reactive functional groups, polyisocyanate, and polyol, is provided. The isocyanate-reactive functional groups, typically one or two, are attached to only a single end of the polyorganosiloxane chains. The polymeric material may be used to form coatings on a substrate and to inhibit fouling on surfaces exposed to aqueous conditions. | 2010-11-04 |
20100280149 | ECOLOGICALLY FRIENDLY COMPOSITION CONTAINING BENEFICIAL ADDITIVES - One embodiment is a composition comprising water; starch; natural fibrous materials; one or more additives to improve certain properties such as heat transfer, microbial resistance, scavenging activity or shelf life; a mold release agent; flavoring agents; coloring agents; and/or wax emulsions, proteins, or other natural polymeric compounds to adjust the product properties for particular applications. | 2010-11-04 |
20100280150 | PRE-PROCESSED THERMOPLASTIC COMPOUND - A pre-processed polymer composite is disclosed comprising a heat-sensitive polymer resin particle; particles of colorant or functional additive in association with the heat-sensitive polymer resin particle; and a thermoplastic encapsulant to form a film around the associated polymer and colorant or functional additive particles. The method of making the polymer composite avoids a melting of the heat-sensitive polymer resin particles, which avoids contributing to heat history of the polymer prior to extrusion or molding into the form of the final plastic article. | 2010-11-04 |
20100280151 | TOUGHENED FIBER REINFORCED POLYMER COMPOSITE WITH CORE-SHELL PARTICLES - Embodiments disclosed herein include a resin composition comprising two or more different kinds of thermosetting resins, wherein at least one of the two or more different kinds of the thermosetting resins is a multifunctional resin, and a core-shell particle having a core and a shell, wherein a composition of the core is different from a composition of the shell and the composition of the shell has a branched polymer structure comprising at least one main chain and at least one side chain, the main chain or the side chain containing at least one functional group that reacts with the thermosetting resin, a method of manufacturing the resin composition, and a composite comprising a reinforcing fiber and the resin composition. | 2010-11-04 |
20100280152 | Thermoformable and RF Sealable Plastic Packaging Material - A thermoformable packaging material, in an exemplary embodiment, includes a thermoplastic composition that includes a polyethylene terephthalate modified with an isophthalic acid co-monomer. The amount of isophthalic acid co-monomer used is sufficient to render the thermoplastic composition RF sealable. | 2010-11-04 |
20100280153 | MODIFIED PROPYLENE RESIN - It is an object of the present invention to provide a modified propylene resin containing very small amounts of low-crystalline and low-molecular-weight components. The present invention relates to a modified propylene resin characterized by satisfying the following requirements (1) to (4). (1) The melting point (Tm) measured with a differential scanning calorimeter (DSC) is 140° C. or higher. (2) The amount of grafts of ethylenic unsaturated bond-containing monomer after hot xylene washing is 0.1 to 5 percent by weight. (3) The amount of components soluble in o-dichlorobenzene at 70° C. is 1.5 percent by weight or less. (4) The intrinsic viscosity [η] is 0.1 to 4 dl/g. | 2010-11-04 |
20100280154 | Wood Treatment Composition and Process - The present invention comprises a fire resistant wood product and method of manufacture thereof. In one embodiment, the fire resistant wood product comprises a resin and a fire retardant composition, wherein the resin comprises an isocyanate and the fire retardant composition comprises a boron containing compound. | 2010-11-04 |
20100280155 | Alkyltin Sulfanyl Mercaptocarboxylates Having Terminal Thiol Groups - An alkyltin compound of specified formula which has utility as an excellent stabilizer for a halogen-containing resin. The alkyltin compound has from 1-3 terminal thiol groups. | 2010-11-04 |
20100280156 | POLYACETAL RESIN COMPOSITION - The present invention provides a polyacetal resin composition having a metallic appearance, suppressing the generation of volatile organic compound (VOC), in particular formaldehyde from the molded article thereof to an extremely low level and giving excellent weathering (light) resistance. Specifically, (A) 100 parts by weight of a polyacetal copolymer containing 1.0 mmol/kg or smaller of a hemiformal terminal group, 2.0 mmol/kg or smaller of a formyl terminal group, 0.5 wt % or smaller of an unstable terminal group, (B) 0.03 to 0.30 part by weight of a hindered phenol-based antioxidant, (C) 0.01 to 1 part by weight of a guanamine compound, (D) 0.2 to 1 part by weight of a hindered amine-based stabilizer, and (E) 0.1 to 1 part by weight of an ultraviolet absorber, and (F) 1 to 20 parts by weight of a metallic pigment are blended together. | 2010-11-04 |
20100280157 | LIQUID RHEOLOGICAL ADDITIVE SUITABLE FOR THICKENING SOLVENT BORNE, PIGMENT CONTAINING SYSTEM - A thixotropy imparting composition. The composition comprises the reaction products of: one or more polyesters from one or more polyols having at least two hydroxyl moieties; and one or more polycarboxylic acids having at least two carboxylic acid moieties; and one or more basic compounds, wherein said polyesters have at least two active carboxylic acid moieties as end groups and at least a portion of said carboxylic acid moieties are in the carboxylate anion form. This composition may further comprise one or more diluents. The composition exists as a liquid. The composition may be used in a non-aqueous fluid system as a rheological additive in combination with one or more particulate materials, wherein said rheological additive imparts thixotropy to said system. | 2010-11-04 |
20100280158 | INK COMPOSITION FOR INKJET PRINTING - An ink composition for ink-jet printing does not cause clogging of nozzles of an ink-jet printer during printing, thereby providing a print of desired printing quality; which ensures an appropriate drying rate of printed images; and which attains excellent color development. The ink composition for ink-jet printing, containing a pigment, a binder resin, a pigment dispersant, and a solvent, wherein the solvent is formed of (1) at least one glycol ether and at least one of a lactone compound and 2-pyrrolidone, or (2) at least one glycol ether acetate and at least one of cyclohexane and isophorone. | 2010-11-04 |
20100280159 | FLAME RETARDANT THERMOPLASTIC COMPOSITION AND ARTICLES FORMED THEREFROM - An embodiment of a thermoplastic resin composition can comprise a cyanophenyl endcapped polycarbonate resin; a potassium diphenyl sulphon-3-sulphonate; and brominated polycarbonate; wherein the composition. In some embodiments, when the composition is in the form of a 3 mm thick extruded sheet, the sheet has a smoke density of less than 200 at an exposure period of 240 seconds in accordance with the smoke density test as set forth in ASTM E662-06, and has no burning drips on the sheet for a duration of 10 minutes in accordance with the flammability test as set forth in NF-P-92-505. | 2010-11-04 |
20100280160 | FLAME RETARDANT THERMOPLASTIC COMPOSITION AND ARTICLES FORMED THEREFROM - A thermoplastic composition can comprise: polycarbonate, aromatic sulphone sulphonate, aromatic sulphonate, and brominated polycarbonate. In an embodiment, when the composition is formed into a 3 mm thick extruded sheet, the sheet can have a smoke density of less than 200 at an exposure period of 240 seconds in accordance with the smoke density test as set forth in ASTM E662-06, and a burn length of less than 150 mm, a drip flame time of less than 3 seconds, and an overall flame time of less than 15 seconds in accordance with the flammability test as set forth in 14 C.F.R. 25.853, Appendix F, Part I(a)(1)(ii). | 2010-11-04 |
20100280161 | COMPOSITION CONTAINING SILSESQUIOXANE AND SILSESQUIOXANE-CONTAINING HYDROXYALKYL CELLULOSE RESIN COMPOSITION - It is to provide a silsesquioxane having α,β-diol group, and to provide an organic-inorganic hybrid resin composition comprising silsesquioxane and hydroxyalkyl cellulose. A composition comprising a cage-type structure of silsesquioxane represented by general formula (A), and a partially cleaved cage-type structure of silsesquioxane represented by general formula (B); | 2010-11-04 |
20100280162 | DISPERSING AGENT - A dispersing agent and a composition including a pigment and the dispersing agent are provided. The dispersing agent includes a branched alcohol alkoxylate having the following formula (I): | 2010-11-04 |
20100280163 | THERMOSETTING SILICONE RUBBER COMPOSITION - Disclosed is a thermosetting silicone rubber composition containing 0.001-10% by mass of a cerium oxide powder. This thermosetting silicone rubber composition is characterized in that when 0.1% by mass of the cerium oxide powder is dispersed in an alkenyl group-containing dimethylpolysiloxane raw rubber, the total light transmittance according to JIS K7105 through the resulting rubber having a thickness of 1 mm is not less than 90%; This thermosetting silicone rubber composition is excellent in thermal stability during production or in the uncured state, and enables to obtain a silicone rubber having excellent heat resistance after curing. | 2010-11-04 |
20100280164 | Inorganic Composite - The invention relates to a nonmetallic inorganic or mineral particulate polymer composite having enhanced viscoelastic and rheological properties. | 2010-11-04 |
20100280165 | USE OF HIGHLY-BRANCHED POLYMERS FOR PRODUCING POLYMER DISPERSIONS WITH IMPROVED FREEZE/THAW STABILITY - The present invention relates to a method of producing polymer dispersions having improved freeze-thaw stability, by adding a highly branched polymer to said dispersions, and also to the use of highly branched polymers for this purpose. | 2010-11-04 |
20100280166 | HETEROPHASIC POLYPROPYLENE WITH HIGH IMPACT PROPERTIES - The present invention relates to a heterophasic polypropylene resin comprising a polypropylene homo- or copolymer matrix phase (A) and an ethylene-propylene copolymer phase (B) dispersed within the matrix, wherein the heterophasic polypropylene resin has a fraction insoluble in p-xylene (XCU) at 25° C. with an intrinsic viscosity of 2.0 dl/g or less, determined according to DIN EN ISO 1628-1 and -3, and a fraction soluble in p-xylene (XCS) at 25° C. having an intrinsic viscosity of 2.0 to 4.5 dl/g, determined according to DIN EN ISO 1628-1 and -3, and an amount of ethylene monomer units of 60 to 85 mol %, a heterophasic polypropylene composition comprising such a resin, a process for preparing that resin, and an article made thereof. | 2010-11-04 |
20100280167 | IMPACT STRENGTH IMPROVING AGENT FOR EPOXY RESIN COMPOSITIONS - The present invention relates to a butadiene/acrylonitrile copolymer CTBN, modified by epoxy solid resin and terminated by carboxyl groups, the terminal epoxy groups thereof also having optionally been reacted. A polymer of this type is used in particular as an impact strength improving agent in epoxy resin compositions and has proven to be particularly advantageous for gluing on or of metal surfaces. It results in a significant reduction of the infiltration with corrosion, which in turn ensures a long-lived adhesive bond. | 2010-11-04 |
20100280168 | PLASTICIZER COMPOSITION - The invention relates to a composition containing at least one plasticizer and silicon dioxide particles having an average particle size of 150 nm or less. According to the invention, the proportion of silicon dioxide particles is from 10 to 80% by weight and the proportion of plasticizer is from 90 to 20% by weight, where the sum of the proportions of silicon dioxide particles and of the plasticizer is at least 80% by weight. The invention makes it possible to mix nanoparticles into any polymeric materials in a simple way. | 2010-11-04 |
20100280169 | AMPHOLYTIC COPOLYMER WITH CONTROLLED ARCHITECTURE - The invention relates to novel ampholytic copolymers having a controlled architecture. These copolymers can particularly be used in aqueous compositions. | 2010-11-04 |
20100280170 | TWO-COMPONENT COATING COMPOSITIONS - The present invention relates to isocyanate-curing two-component coating compositions containing urethane compounds having at least two —O—CO—NH-groups. | 2010-11-04 |
20100280171 | Aerogel / Polymer Composite Materials - The invention provides new composite materials containing aerogels blended with thermoplastic polymer materials at a weight ratio of aerogel to thermoplastic polymer of less than 20:100. The composite materials have improved thermal insulation ability. The composite materials also have better flexibility and less brittleness at low temperatures than the parent thermoplastic polymer materials. | 2010-11-04 |
20100280172 | Reinforced Silicone Resin Film and Method of Preparing Same - A method of preparing a reinforced silicone resin film, the method comprising impregnating a fiber reinforcement in a silicone composition comprising (A) a silicone resin having disilyloxane units and (B) an organic solvent, and curing the silicone resin of the impregnated fiber reinforcement; and a reinforced silicone resin film prepared according to the method. | 2010-11-04 |
20100280173 | CONJUGATED DIENE POLYMER, PROCESS FOR ITS PRODUCTION AND RUBBER COMPOSITIONS CONTAINING THE SAME - A process for producing a conjugated diene-based polymer which comprises, in the first modification, modifying a conjugated diene-based polymer having active chain ends, which is obtained by polymerizing a diene-based monomer singly or with other monomers and has a content of a cis-1,4 unit of 75% by mole or greater in the conjugated diene portion of the main chain, by reacting the active chain ends with a hydrocarbyloxysilane compound and reacting the modified polymer with a specific compound such as a hydrocarbyloxysilane compound, and a rubber composition containing the polymer modified in accordance with the above process and, preferably, 10 to 100 parts by weight of silica and/or carbon black per 100 parts by weight of the rubber component containing the modified polymer, are provided. The rubber composition containing silica and/or carbon black exhibits improved fracture properties, abrasion resistance, low heat buildup property and excellent workability. A process for producing a conjugated diene-based polymer exhibiting improved cold flow, a polymer produced in accordance with the process, and a rubber composition and a tire using the polymer are also provided. | 2010-11-04 |
20100280174 | Method of Manufacturing a Polymer Blend - Hydrophobic polymer surfaces whose level of protein binding is less than about 50-80 ng/cm | 2010-11-04 |
20100280175 | Compositions and Methods for Maintaining or Restoring Adhesive Properties of a Selectively-Releasable Adhesive - In one embodiment, a method for restoring adhesive strength of an adhesive that has lost at least some of its adhesive strength includes applying a restoration agent to the adhesive. In one embodiment, a selectively-releasable adhesive includes a copolymer formed from a multifunctional alcohol and a multifunctional carboxylic acid, wherein the copolymer has been cured the equivalent of less than approximately 9 hours at approximately 120° C. and 100 milliTorr. | 2010-11-04 |
20100280176 | POLYCARBONATE COMPOSITION COMPRISING NANOMATERIALS - A method of preparing a polycarbonate nanocomposite comprising forming a reactant mixture comprising a nanomaterial, a solvent, a dihydroxy compound and an activated carbonate; and polymerizing the dihydroxy compound and the activated carbonate in the presence of the solvent to form the polycarbonate nanocomposite is disclosed. Also disclosed are polycarbonate nanocomposites prepared in accordance with this method, and thermoplastic compositions comprising the polycarbonate nanocomposites. Also disclosed are polycarbonate compositions comprising the nanomaterial. | 2010-11-04 |
20100280177 | MULTICOMPONENT ASSEMBLIES HAVING ENHANCED BINDING PROPERTIES FOR DIAGNOSIS AND THERAPY - An organized mobile multicomponent conjugate (OMMC) and method of using to enhance binding of weakly binding compounds to a target. A lamellar structure containing at least two binding compounds is assembled under conditions in which the binding compounds self-regulate in or on the lamellar structure, forming a cooperative ensemble that is capable of binding with enhanced affinity to a complementary affinity site on a target. Each binding compound is bound to the lamellar surface, and may be connected by a linker. The OMMC may contain an effector molecule, such as a diagnostic or therapeutic agent, for administration to a patent who is then diagnosed or treated using the effector molecule. | 2010-11-04 |
20100280178 | MODIFIED ETHYLENE-VINYL ALCOHOL COPOLYMER AND METHOD FOR THE PRODUCTION THEREOF - Provided is a modified ethylene-vinyl alcohol copolymer (C) having an ethylen content of 5 to 55 mol %, which contains a specific structural unit (I) in an amount of 0.3 to 40 mol % and may be obtained by reacting an ethylene-vinyl alcohol copolymer (A) with a monofunctional epoxy compound (B) having a molecular weight of not more than 500. This can be produced by a method for producing the modified ethylene-vinyl alcohol copolymer (C) which comprises melting and kneading an ethylene-vinyl alcohol copolymer (A) with a monofunctional epoxy compound (B) in an extruder. The modified ethylene-vinyl alcohol copolymer (C) is superior to a unmodified ethylene-vinyl alcohol copolymer (A) in transparency, stretchability, flexibility and flexing resistance due to the specific structural unit (I) incorporated therein, and thus, can be used as a barrier material in various applications requiring the above performance capabilities. | 2010-11-04 |
20100280179 | ADHESIVE COMPOSITION - The present invention relates to a moisture-curable adhesive composition applicable to production of automobile interior parts, having excellent adhesion to polyolefins such as polypropylene and polyethylene, and having excellent heat resistance. More specifically, the present invention relates to an adhesive composition comprising: a styrene block copolymer (A) having at least one unsaturated bond, a hydrogenated styrene block copolymer (B) having a styrene content of 15% by weight or more, a silane compound (C) having an unsaturated bond, an acid-modified polyolefin resin (D), and a polymerization initiator (E). | 2010-11-04 |
20100280180 | Thermoplastic Resin Composition - A thermoplastic resin composition includes (A) 60 to 96 parts by weight of a polycarbonate resin, (B) 3 to 30 parts by weight of a polyalkyl(meth)acrylate resin having a weight average molecular weight of 30,000 g/mol or less, and (C) 1 to 10 parts by weight of polydialkyl-diarylsiloxane. The thermoplastic resin composition according to the present invention can have excellent scratch resistance and can be used in molded articles requiring high coloring properties such as exterior parts, vehicle precision parts, and the like. | 2010-11-04 |
20100280181 | HETEROPHASIC POLYPROPYLENE WITH HIGH FLOWABILITY AND EXCELLENT LOW TEMPERATURE IMPACT PROPERTIES - The present invention relates to a heterophasic polypropylene resin comprising a propylene homo- or copolymer matrix (A) and an ethylene-propylene rubber phase (B) dispersed within the matrix, wherein the heterophasic polypropylene resin has a fraction insoluble in p-xylene at 25° C. (XCU) with an intrinsic viscosity of 1.5 dl/g or less, determined according to DIN EN ISO 1628-1 and -3 and an amount of propylene monomer units of at least 95 mol %, and a fraction soluble in p-xylene at 25° C. (XCS) with an intrinsic viscosity of 1.5 to 3.0 dl/g, determined according to DIN EN ISO 1628-1 and -3, and an amount of propylene monomer units of 50 to 75 mol %, and a MFR (2.16 kg, 230° C.) of more than 100 g/10 min, determined according to ISO 1133, a heterophasic polypropylene composition comprising such a resin, a process for preparing that resin, and an article made thereof. | 2010-11-04 |
20100280182 | METHOD FOR THE PRODUCTION OF (METH) ACRYLATE-BASED ABA TRIBLOCK COPOLYMERS - The invention relates to a method for producing meth)acrylate-based ABA triblock copolymers in which the A blocks are amine-functionalized. | 2010-11-04 |
20100280183 | POLYAMINE-POLYACRYLATE DISPERSANT - The invention relates to a liquid dispersant based on polyamine-graft-polyacrylate blend, its preparation and its use in solvent borne systems, especially to a polyamine-g-polyacrylate grafted copolymer blend of the general formula (1) or a mixture of formula (1) and YT-(A1,A2)-Y1 wherein T is a polyamine or polyimine, A1 is a bridging bond which is selected from amide or amide, A2 is a —N—C— bridging bond, Y is an acrylate residue of the general formula (2), wherein, R | 2010-11-04 |
20100280184 | SURFACE FUNCTIONALISATION OF PLASTIC OPTICAL FIBRE - A process is provided for the covalent attachment of an indicator to a plastic optical fibre by functionalising the surface of the optical fibre to provide a polymerisable group, and polymerising an indicator monomer, optionally together with a hydrogel-forming monomer, to the fibre surface. This provides an optical fibre having covalently linked to its surface an indicator, typically an indicator encased in a hydrogel. The plastic optical fibre is useful as a sensor. | 2010-11-04 |
20100280185 | HIGHLY-BRANCHED MELAMINE POLYMERS - A process for preparing highly branched melamine polymers, wherein melamine is reacted with 1.5 to 4 mol, per mole of melamine, of one or more diamines or polyamines having at least two primary amino groups, it being possible for up to 25 mol % of the diamines or polyamines to have three or more primary amino groups and for up to 50 mol % of the diamines or polyamines to be replaced by amines having only one primary amino group, in the presence of an acidic catalyst. | 2010-11-04 |
20100280186 | FURANIC-MODIFIED AMINE-BASED CURATIVES - Aromatic polyamines are derivatized with polycarboxylic acids or their derivatives to form polyamine amides) containing pendant amine groups; the derivatives have enhanced curative properties when used as curatives for polyureas, hybrid epoxy-urethanes, hybrid urea-urethanes, chain extenders for polyurethane and polyurea elastomers, and also for reaction injection molding (RIM) products. | 2010-11-04 |
20100280187 | REACTION INJECTION MOLDED POLYURETHANES MADE USING HIGH LEVELS OF NATURAL OIL-BASED POLYOLS - Polyurethane and/or polyurea polymers are produced in a reaction injection molding process. The high equivalent weight isocyanate-reactive materials include a high proportion of a hydroxymethylated polyester which can be prepared using annually renewable starting materials. | 2010-11-04 |
20100280188 | 4-HYDROXYPHENYLALKYLAMINE DERIVATIVE - The present invention relates to a compound represented by the following general formula (I): | 2010-11-04 |
20100280189 | SYNTHESIS OF CYCLOALIPHATIC SUBSTITUTED SILANE MONOMERS AND POLYSILOXANES FOR PHOTO-CURING - The present invention generally relates to compositions including linear cycloaliphatic siloxane polymers, and the cyclic cycloaliphatic siloxane oligomers from which they are made. The present invention also generally relates to methods for making cycloaliphatic siloxane polymers, and the cyclic cycloaliphatic siloxane oligomers from which they are made. Some embodiments relate to cationic polymerization of methyl, cyclopentyl, and/or cyclohexyl substituted polysiloxanes. In some embodiments the cationic polymerization is a cationic ring-opening polymerization. | 2010-11-04 |
20100280190 | CURABLE CAGE-TYPE SILICONE COPOLYMER AND PROCESS FOR PRODUCTION THEREOF AND CURABLE RESIN COMPOSITION COMPRISING CURABLE CAGE-TYPE SILICONE COPOLYMER AND CURED PRODUCT THEREOF - Disclosed is a cage-type copolymer in which a cage structure is incorporated in its main chain. Also disclosed is a curable resin composition comprising the said copolymer. Specifically disclosed is a curable cage-type silicone copolymer with a constituent unit represented by general formula (1) Y—[Z—(O | 2010-11-04 |
20100280191 | EPOXY RESIN COMPOSITION - A process for making a molded composite comprising the following steps: reacting a reaction mass containing a polyepoxide, in the proportion of about 20% to 50% with respect to the reaction mass, a diol, in the proportion of about 10% to 20% with respect to the reaction mass, a hardener, in the proportion of about 20% to 50% with respect to the reaction mass, in the presence of an accelerator in the proportion of about 0.5 to 10.0% with respect to the reaction mass either alone or in solution with compatible diluents, to obtain an epoxy resin mix having intrinsic viscosity in the range of 100 to 850 cPs, pouring the resin mix in a mold having an in-situ glass fiber scaffold at a mold temperature in the range of 45 to 50 C and applying pressure to the resin mix in the mold to form a compressed green composition: partially curing the compressed green composition at a temperature in the range of 60 to 80 C to obtain a partially cured composite; and further curing the partially cured composite at a temperature in the range of 80 to 90 C to obtain a fully cured composite. The composite is used for structural applications like windmill blades, yachts, domes, ships made from a composite made in accordance with the process as mentioned herein. | 2010-11-04 |
20100280192 | Fast Curable Epoxy Compositions Containing Imidazole- And 1-(Aminoalkyl) Imidazole-Isocyanate Adducts - Epoxy curing agents comprising imidazole-isocyanate adducts, including 1-(aminoalkyl) imidazole-isocyanate adducts and especially 1-(3-aminopropyl) imidazole-isocyanate adducts, and their use as curing agents in heat curable one-component epoxy resin compositions. | 2010-11-04 |
20100280193 | ANTISTATIC POLY(HYDROXYALKANOIC ACID) COMPOSITIONS - Disclosed are toughened, antistatic resin composition and an article comprising the composition wherein the composition comprises or consists essentially of poly(hydroxyalkanoic acid), such as polylactic acid; an impact modifier comprising an ethylene copolymer; and an ion conducting polymer. | 2010-11-04 |
20100280194 | MOLDED ARTICLE AND METHOD FOR PRODUCING THE SAME - This invention provides a molded article that is excellent in planar impact resistance and shape stability by the use of a composition comprising a polyolefin-based polymer and an aliphatic polyester-based polymer and that is less likely to experience layer separation at the time of molding and a method for producing the same. Such a molded article comprises a resin composition comprising a polyolefin-based polymer (A), an aliphatic polyester-based polymer (B), an ethylene-α olefin-based elastomer (C), and an epoxy group-containing polyolefin-based polymer (D), and the aliphatic polyester-based polymer (B) has an aspect ratio A | 2010-11-04 |
20100280195 | PROCESS FOR PREPARING POLYOXYMETHYLENE HOMOPOLYMERS OR COPOLYMERS BY HOMOPOLYMERIZATION OR COPOLYMERIZATION OF TRIOXANE, STARTING FROM METHANOL - A process for preparing polyoxymethylene homopolymers or copolymers ( | 2010-11-04 |
20100280196 | PREPOLYMERIZED CATALYST FOR OLEFIN POLYMERIZATION, METHOD OF PRODUCING THIS PREPOLYMERIZED CATALYST AND METHOD OF PRODUCING OLEFIN POLYMER - A method of producing a prepolymerized catalyst for olefin polymerization comprising a fine powder removal step of removing fine particles from olefin-prepolymerized catalyst particles for olefin polymerization. The prepolymerized catalyst having a low fine particle content is applicable suitably to the field of continuous polymerization of olefins. | 2010-11-04 |
20100280197 | MODIFIED PARTICLE, SUPPORT, CATALYST COMPONENT FOR ADDITION POLYMERIZATION, CATALYST FOR ADDITION POLYMERIZATION, AND PROCESS FOR PRODUCING ADDITION POLYMER - A process for producing a modified particle, which involves the step of contacting with one another compounds (a), (b) and (c) represented by the defined general formulas M | 2010-11-04 |
20100280198 | Olefin Acrylate Emulsion Copolymerization - A polymerization process to copolymerize hydrophobic ethylenically unsaturated C | 2010-11-04 |
20100280199 | COMPOSITIONS THAT CAN PRODUCE POLYMERS - This invention provides a compositions that are useful for polymerizing at least one monomer into at least one polymer. | 2010-11-04 |
20100280200 | Water Permeable Fluoropolymer Articles - A water permeable fluoropolymer article is described comprising a functional copolymer of TFE, PSVE and sulfonic acid pendant to the polymer chain, as well as methods of making the article. The method comprises providing a copolymer membrane comprising a microstructure characterized by nodes interconnected by fibrils, wherein said membrane, immersing said membrane in hot water for a period of time to render the membrane water permeable. | 2010-11-04 |
20100280201 | POLYMERS CONTAINING QUATERNIZED NITROGEN - The invention provides polymers, methods of preparing polymers, and compositions that include polymers, wherein said polymers include a plurality of two-carbon repeating units in a polymer chain, wherein one or more of the two-carbon repeating units of the polymer chain have tertiary amine or pyridine-containing substituents; and at least about 10% of the nitrogen atoms of the tertiary amine or pyridine-containing substituents are quaternized with alkyl groups or with an alkyl group that contains one or more ethylene glycol groups. The alkyl or ethoxylated alkyl groups can also be at least partially fluorinated. The polymers can be used to provide antimicrobial surfaces and antifouling coatings. | 2010-11-04 |
20100280202 | VINYL ALCOHOL-BASED POLYMER AND FILM CONTAINING THE SAME - Provided are a polyoxyalkylene modified vinyl alcohol-based polymer, including a polyoxyalkylene group in side chain, wherein the vinyl alcohol-based polymer has a viscosity average degree of polymerization P of from 200 to 5000, has a degree of saponification of from 20 to 99.99 mol %, and has an amount S of polyoxyalkylene modification of from 0.1 to 10 mol % and a film containing the same. By way of them, a polyvinyl alcohol-based polymer that is soluble in water and also high in viscosity, and a film that is less in a decrease of tensile elastic modulus when conditioned in high humidity, is excellent in water repellency on the film surface, and exhibits water solubility are provided. | 2010-11-04 |
20100280203 | GRAFT POLYMERS HAVING OLIGOALKYLENIMINE SIDE CHAINS, PROCESS FOR THEIR PREPARATION AND THEIR USE - Graft polymers whose grafting base is selected from the group consisting of polymers having vinylamine units, polyamines, polyamidoamines and polymers of ethylenically unsaturated acids and which comprise exclusively oligoalkylenimine side chains as side chains, process for the preparation of graft polymers having oligoalkylenimine side chains, at least one oligoalkylenimine which comprises a terminal aziridine group being grafted onto one of said grafting bases, and the use of the graft polymers thus obtainable as process chemicals in the production of paper, as antimicrobial coating materials, as builders in detergents and for the treatment of metal surfaces. | 2010-11-04 |
20100280204 | METHOD FOR PRODUCING N-METHYL-N-VINYLACETAMIDE HAVING IMPROVED STABILITY AND POLYMERIZABILITY - The present invention relates to a method for producing N-methyl-N-vinylacetamide, which comprises a step for controlling the N-1,3-butadienyl-N-methylacetamide content in N-methyl-N-vinylacetamide to 0.01-150 ppm. This method enables production of N-methyl-N-vinylacetamide having a stable quality, which can be controlled in stability and polymerizability as a monomer. N-methyl-N-vinylacetamide produced by the method enables production of an N-methyl-N-vinylacetamide polymer having stable physical properties such as a molecular weight. | 2010-11-04 |
20100280205 | PROCESS FOR PREPARING (METH)ACRYLATES - Process for preparing (meth)acrylates of the formula (I) | 2010-11-04 |
20100280206 | POLYETHYLENE COPOLYMER - This application relates to an ethylene polymer having a weight average molecular weight of at least 120,000 including 1-50 tertiary double bonds per 10,000 carbon atoms. | 2010-11-04 |
20100280207 | Method for Optimizing energy Efficiency in a Polymerization Process - The present invention relates to a process for cooling a polymerization reaction for producing polyolefin comprising the steps of:
| 2010-11-04 |
20100280208 | THIETANE COMPOUND, POLYMERIZABLE COMPOSITION COMPRISING THE COMPOUND, AND USE OF THE COMPOSITION - Disclosed is a thietane compound represented by the following general formula (1), | 2010-11-04 |
20100280209 | CURABLE COMPOUND COMPRISING SILYLATED POLYURETHANE - A method for producing a silylated polyurethane including the steps: (A) converting (i) at least polyol compound having a molecular weight of 4,000-30,000 g/mol and at least one monofunctional compound relative to isocyanates and (ii) at least one diisocyanate at a stoichiometric excess of the sum of the polyol compound(s) and monofunctional compound relative to the diisocyanate compound(s), whereby a hydroxyl-terminated polyurethane prepolymer is formed; and (B) converting the polyurethane prepolymer and one or more isocyanate silane(s) of the formula (I): OCN—R—Si—(R1) | 2010-11-04 |
20100280210 | POLYSILOXANE, METHOD FOR PRODUCING THE SAME, AND METHOD FOR PRODUCING CURED PRODUCT OF THE SAME - The present invention has an object to provide a polysiloxane which is a liquid substance having low viscosity, is excellent in curing workability, and has excellent heat resistance in an obtained cured material, and to a production method of a cured material using the polysiloxane. Specifically disclosed is a polysiloxane which is obtained by hydrolysis and polycondensation of a silicon compound having three hydrolyzable groups, a silicon compound having two hydrolyzable groups and a silicon compound having one hydrolyzable group, and is characterized by containing a hydrosilylatable carbon-carbon unsaturated group, a hydrosilyl group and an alkoxysilyl group, and having a number average molecular weight of 500 to 20,000. | 2010-11-04 |
20100280211 | FAST CURABLE EPOXY COMPOSITIONS CONTAINING IMIDAZOLE-AND 1 -(AMINOALKYL) IMIDAZOLE-ISOCYANATE ADDUCTS - Epoxy curing agents comprising imidazole-isocyanate adducts, including 1-(aminoalkyl)imidazole-isocyanate adducts and especially 1-(3-aminopropyl)imidazole-isocyanate adducts, and their use as curing agents in heat curable one-component epoxy resin compositions. Epoxy curing agents comprising imidazole-isocyanate adducts comprising the reaction product of at least one imidazole, at least one polyisocyanate and at least one diamine. | 2010-11-04 |
20100280212 | POLYMER DISPERSIONS IN POLYESTER POLYOLS - The present invention relates to polymer dispersions in polyester polyols, a process for producing them and their use for the production of polyurethanes, in particular microcellular polyurethanes. These polyester polyols have sulfur atoms and are free of olefinically unsaturated groups. | 2010-11-04 |
20100280213 | PROCESS FOR PRODUCING POLYTHIOL COMPOUND FOR OPTICAL MATERIALS, AND POLYMERIZABLE COMPOSITION CONTAINING POLYTHIOL COMPOUND - Provided is a process for producing a polythiol compound for an optical material, the method includes reacting 2-mercaptoethanol with an epihalohydrin compound to give polyalcohol, and preparing a polythiol compound through the polyalcohol, wherein a content of bis(2-hydroxyethyl)disulfide in the 2-mercaptoethanol is 0.5 wt % or less. | 2010-11-04 |
20100280214 | HIGHLY PURE AMPHIPHILIC COPOLYMER COMPRISING HYDROPHOBIC BLOCK FROM ALPHA-HYDROXY ACID AND PROCESS FOR THE PREPARATION THEREOF - Disclosed are a highly pure amphiphilic block copolymer including a hydrophobic polymer block of a poly(α-hydroxy acid), and a method for preparing the same. The method for preparing a highly pure amphiphilic block copolymer including a hydrophobic polymer block of a poly(α-hydroxy acid) includes removing α-hydroxy acid, lactone monomers thereof, oligomers thereof and an organometal catalyst in polymerizing the amphiphilic block copolymer. | 2010-11-04 |
20100280215 | NITROUS BRIDGED DERIVATIVES OF 6H-DIBENZ[C,E][1,2]-OXAPHOSPHORINE-6-OXIDES, PROCESS FOR THE PREPARATION AND USE THEREOF - The invention refers to nitrous bridged derivatives of 6H-dibenz[c,e][1,2]-oxaphosphorine-6-oxides, a process for the preparation thereof and their use as flameproofing agents for polymers such as polyesters, polyamides, polycarbonates, polystyrenes, polyethylene, polypropylene, phenolic and epoxy resins. The derivatives have the Formulae I or II: | 2010-11-04 |
20100280216 | METHOD OF PREPARING ORGANIC POROUS SOLIDS AND SOLIDS OBTAINABLE BY THIS METHOD - The present invention relates to a method of preparing porous solids, which method comprises polymerizing, in a salt melt or a eutectic mixture of salt melt containing at least one Lewis acidic salt, cyano monomers having at least one or at least two cyano groups in their molecule, wherein the at least one or at least two cyano groups are bonded to a rigid linking group in the cyano monomer, as well as to the porous solids obtainable by that method. Owing to their porosity and the associated extremely high specific surface area, the porous solids are useful as sorbents, filtering and insulating materials, as well as catalyst carriers. | 2010-11-04 |
20100280217 | POLYMERS FUNCTIONALIZED WITH HETEROCYCLIC NITRILE COMPOUNDS - A method for preparing a functionalized polymer, the method comprising the steps of preparing a reactive polymer and reacting the reactive polymer with a heterocyclic nitrile compound. | 2010-11-04 |
20100280218 | POLYMERIC MATERIALS FROM RENEWABLE RESOURCES - Disclosed are polymers that include components produced from renewable resources and methods for forming the disclosed polymers. The polymers include the reactive intermediates that in turn include components derived from, for example, lactide or sorbitol. The reactive intermediates can be polymerized with each other as well as with more traditional resins to form polymeric networks. In one embodiment, the disclosed intermediates can be utilized in forming vinyl ester resins. In particular, the vinyl ester-styrene resins and thermoset networks formed therefrom including the disclosed intermediates can include lower styrene content than previously known vinyl ester-styrene resins, and can exhibit physical characteristics such as glass transition temperature and flexural strength properties equal to previously known vinyl ester-styrene resins that include a higher styrene content. | 2010-11-04 |
20100280219 | OLIGOCARBONATE MOLECULAR TRANSPORTERS - A cyclic carbonate monomer, including: | 2010-11-04 |
20100280220 | Gold binding peptides and shape-and size-tunable synthesis of gold nanostructures - The present invention relates to gold binding peptides and shape- and size-tunable synthesis of gold nanostructures. The present inventions are very useful for the production of well-designed, gold-based architectures. The size- and shape-specific gold nanostructure materials prepared by the present invention may find use as: highly conductive interconnections for single-electron transistors, catalysts for the oxidation of carbon monoxide; biological and chemical sensors; and as contrasting agents for electron microscopic and medical imaging applications. | 2010-11-04 |
20100280221 | Peptide production and purification process - Processes for the synthesis and purification of a Gly-Gly-Val-Leu-Val-Gln-Pro-Gly octapeptide (SEQ ID NO 1). | 2010-11-04 |
20100280222 | CLOSTRIDIAL NEUROTOXIN COMPOSITIONS AND MODIFIED CLOSTRIDIAL NEUROTOXINS - Natural and modified neurotoxins and isolated neurotoxin compositions are described. The neurotoxins may include one or more structural modifications, wherein the structural modification(s) alters the biological persistence, such as the biological half-life and/or a biological activity of the modified neurotoxin relative to an identical neurotoxin without the structural modification(s). In one embodiment, methods of making the modified neurotoxin include using recombinant techniques. In another embodiment, methods of using the modified neurotoxin to treat conditions include treating various disorders, neuromuscular aliments and pain. | 2010-11-04 |
20100280223 | METHOD FOR DETERMINING AND PREDICTING PROTEIN AUTONOMOUS FOLDING - Techniques for determining an equilibrium structure of a protein in a predetermined environment, the protein having Ramachandran angles and a known denatured structure, are disclosed. In a preferred embodiment, a method is presented which involves determining a maximum RMS volume of the known denatured structure of the protein and calculating at least one force on the protein in its current structure in the predetermined environment. The net torque resulting from the at least one force for each of the Ramachandran angles of the protein is then determined. Then at least one section of the protein structure on a side of a Ramachandran angle with greatest torque is rotated to form a new structure. A new RMS volume for the new structure is then calculated, and the method is repeated using the new structure. The method ceases when the new RMS volume of the new protein structure is not less than the RMS volume of the starting structure. | 2010-11-04 |
20100280224 | MARKER SEQUENCES FOR MULTIPLE SCLEROSIS AND USE THEREOF - The present invention relates to new marker sequences for multiple sclerosis and the diagnostic use thereof together with a method for screening of potential active substances for multiple sclerosis by means of these marker sequences. Furthermore, the invention relates to a diagnostic device containing such marker sequences for multiple sclerosis, in particular a protein biochip and the use thereof. | 2010-11-04 |
20100280225 | FUNGUS-INDUCED INFLAMMATION AND EOSINOPHIL DEGRANULATION - This document relates to methods and materials involved in fungus-induced inflammation and eosinophil degranulation. For example, isolated nucleic acids encoding fungal polypeptides, fungal polypeptides, methods for assessing fungus-induced inflammation, methods for assessing eosinophil degranulation, and methods for identifying inhibitors of fungus-induced inflammation and/or eosinophil degranulation are provided. | 2010-11-04 |
20100280226 | Method for using nano carbon to refine collagen into nanoparticulate collagen - This invention relates to a method of using nano carbon to refine collagen into nanoparticulate collagen. As nano carbon particle are mixed into collagen, the pored structure of the nano carbon absorb and adhere to the collagen outer cell membrane and subsequently tears the collagen apart into nanoparticulates via ultrasound vibration, Thus it creates an advanced nanoparticulate collagen small enough to be practically and efficiently absorbed by the skin when applied directly. | 2010-11-04 |
20100280227 | POLYPEPTIDES THAT BIND BR3 AND USES THEREOF - The present invention relates to novel BR3 binding antibodies and polypeptides, including antagonist and agonist polypeptides. The present invention also relates to the use of the BR3 binding antibodies and polypeptides in, e.g., methods of treatment, screening methods, diagnostic methods, assays and protein purification methods. | 2010-11-04 |
20100280228 | PURIFICATION OF IMMUNOCONJUGATES - The present invention provides methods of purifying immunoconjugates. | 2010-11-04 |
20100280229 | POLYPEPTIDE - The present invention provides a polypeptide inducing the production of an antibody in permucosal administration in the presence of no immunological adjuvant, a composition containing the polypeptide, and use thereof. The present invention solves the above object by providing a polypeptide inserted with a cell attachment motif of a cell adhesive molecule to the peptide which has an amino acid sequence of multiagretope type T cell epitope at the amino terminal side of an inserted linker peptide, and an amino acid sequence of a B cell epitope at the carboxyl terminal side of the inserted linker peptide, a composition containing the polypeptide, and use thereof. | 2010-11-04 |
20100280230 | METHOD OF PREPARING CLARITHROMYCIN - This invention discloses a method of manufacturing clarithromycin, where an erythromycin A 9-oxime thiocyanate salt is used directly to perform an etherification reaction, and then successively silanizattion, methylattion and hydrolysis reactions are sequentially conducted. It is a new process with simple process with a high yield, low cost, less pollution, high quality and is suitable for commercial manufacturing. | 2010-11-04 |
20100280231 | WHITENING AGENT COMPRISING EQUOL OR ITS SACCHARIDE DERIVATIVE AS AN EFFECTIVE INGREDIENT - An object of the present invention is to provide a whitening agent containing a novel whitening substance as an effective ingredient. The above object is attained by providing a whitening agent containing equol and/or equol glycoside, in which one or more glycosyl groups bind to the hydroxyl group(s) of equol, as an effective ingredient. | 2010-11-04 |
20100280232 | MULTICOMPONENT ASSEMBLIES HAVING ENHANCED BINDING PROPERTIES FOR DIAGNOSIS AND THERAPY - An organized mobile multicomponent conjugate (OMMC) and method of using to enhance binding of weakly binding compounds to a target. A lamellar structure containing at least two binding compounds is assembled under conditions in which the binding compounds self-regulate in or on the lamellar structure, forming a cooperative ensemble that is capable of binding with enhanced affinity to a complementary affinity site on a target. Each binding compound is bound to the lamellar surface, and may be connected by a linker. The OMMC may contain an effector molecule, such as a diagnostic or therapeutic agent, for administration to a patient who is then diagnosed or treated using the effector molecule. | 2010-11-04 |
20100280233 | METHOD FOR SAMPLE PREPARATION - A method for preparing a sample by utilizing a mechanical force in the presence of a size stabilizer to break apart the sample to obtain nucleic acid molecules in a usable size range. | 2010-11-04 |
20100280234 | Photocleavable Protecting Groups and Methods for Their Use - Novel compounds are provided which are useful as linking groups in chemical synthesis, preferably in the solid phase synthesis of oligonucleotides and polypeptides. These compounds are generally photolabile and comprise protecting groups which can be removed by photolysis to unmask a reactive group. The protecting group has the general formula Ar—C(R | 2010-11-04 |
20100280235 | METHOD FOR PRODUCING 4'ETHYNYL d4T - Disclosed is a method for mass-producing 4′-ethynyl d4T (4′-ethynyl-2′,3′-didehydro-3′-deoxythymidine) by a simpler process at low cost. Specifically disclosed is a method for producing 4′-ethynyl d4T, which is characterized by comprising a step for introducing a triple bond-containing group into a furfuryl alcohol derivative or a levoglucosenone, by reacting the furfuryl alcohol derivative or levoglucosenone with a certain compound, and a step for reacting a compound represented by the formula (III), which is obtained by the aforementioned step, with thymine. | 2010-11-04 |
20100280236 | METHOD FOR PREPARING TETRAPYRROLE COMPOUNDS AND TETRAPYRROLE COMPOUNDS - A tetrapyrrole compound is prepared by cultivating bacterial cells of | 2010-11-04 |
20100280237 | PREPARATION OF METAL MESOPORPHYRIN COMPOUNDS - A method of preparing metal mesoporphyrin halide compounds is described. The metal mesoporphyrin halide compound may be formed by forming a novel mesoporphyrin IX intermediate compound and then converting the mesoporphyrin IX intermediate to the metal mesoporphyrin halide through metal insertion. The novel intermediate compound may be formed by a catalytic hydrogenation of hemin in acid and subsequent recovery. | 2010-11-04 |
20100280238 | INTRAMOLECULAR AZIDE-ALKYNE CYCLOADDITION - The Huisgen 1,3-dipolar cycloaddition is a ‘click’ reaction that results from the ligation of azides and alkynes to give a triazole moiety. This reaction has been shown to be effective in the formation of a variety of macrocyclic rings. A key point of interest is the regioselectivity and specificity of the cycloaddition. Disclosed herein are specific, selective, and high-yielding methods of azide-alkyne macrocyclization to form 1,4- and 1,5-triazoles and libraries thereof. | 2010-11-04 |
20100280239 | POLYMERIZATION INITIATORS FOR FIBER-REINFORCED POLYMER COMPOSITES AND MATERIALS MADE FROM THE COMPOSITES - Coupling-initiator compounds are described that include a silicon-containing coupling moiety and at least one polymerization initiator moiety. The coupling moiety may be linked to the at least one polymerization initiator moiety by at least one linking moiety. The coupling moiety is capable of coupling the compound to a substrate, while the one or more polymerization initiator moieties are capable of initiating a polymerization of a monomer under polymerization conditions. The coupling-initiator compounds may be included in fiber reinforced polymer composites, where the compounds are coupled to the fibers in the composites and participate in the polymerization of the surrounding polymer. | 2010-11-04 |
20100280240 | BICYCLIC PYRAZOLE COMPOUNDS AS ANTIBACTERIAL AGENTS - Antibacterial compounds, compositions containing them, and methods of use for the inhibition of bacterial activity and the treatment, prevention or inhibition of bacterial infection. | 2010-11-04 |
20100280241 | SPIROOXAZINE RADICAL DERIVATIVES AND REVERSIBLE ISOMERIZATION REACTION - The present invention can provide new spirooxazine radical derivatives of the following general formula (1) which have chromic property enabling the distinction between the radical species and the cation species on the basis of absorption wavelength: | 2010-11-04 |
20100280242 | Method of Preparing Cyclic Carbonates, Cyclic Carbamates, Cyclic Ureas, Cyclic Thiocarbonates, Cyclic Thiocarbamates, and Cyclic Dithiocarbonates - A method of preparing a cyclic monomer, comprising: forming a first mixture comprising a precursor compound, bis(pentafluorophenyl) carbonate, and a catalyst; wherein the precursor compound has a structure comprising a) two or more carbons, and b) two functional groups selected from the group consisting of primary amine, secondary amine, thiol group, hydroxyl group, and combinations thereof; and agitating the first mixture at a temperature effective to form a second mixture comprising the cyclic monomer, the cyclic monomer selected from the group consisting of a cyclic carbonate, a cyclic carbamate, a cyclic urea, a cyclic thiocarbonate, a cyclic thiocarbamate, and a cyclic dithiocarbonate. | 2010-11-04 |
20100280243 | PROCESS FOR PRODUCTION OF 4- (SUBSTITUTED PHENYL) HEXAHYDROPYRIDO [2,1-C] [1,4] OXAZIN-6-ONE - 4-(Substituted phenyl)hexahydropyrido[2,1-c][1,4]oxazin-6-one represented by formula (I) or a salt thereof is useful as an intermediate for the production of a bicyclic cinnamide compound which is an Aβ production inhibitor. 4-(Substituted phenyl)hexahydropyrido[2,1-c][1,4]oxazin-6-one or the salt thereof can be produced in an industrially advantageous manner by subjecting a compound represented by formula (II) or a salt thereof to an intramolecular condensation reaction. | 2010-11-04 |
20100280244 | PROCESS FOR PREPARING N-SUBSTITUTED HYDROXYPYRIMIDINONE CARBOXAMIDES - Processes for preparing certain N-arylalkyl-1-(alkyl or aralkyl)-2-acylaminoalkyl-5-hydroxy-6-oxo-1,6-dihydropyrimidine-4-carboxamides are disclosed. In one embodiment, the process comprises acylating the free amine in the corresponding N-arylalkyl-1-(alkyl or aralkyl)-2-aminoalkyl-5-ester protected hydroxy-6-oxo-1,6-dihydropyrimidine-4-carboxamide and then deprotecting the 5-hydroxy by base hydrolysis. The hydroxypyrimidinone carboxamide products of the process are HTV integrase inhibitors which are useful for treating HTV infection, treating AIDS, or delaying the onset or progression of AIDS. Certain esterified N-arylalkyl hydroxypyrimidinone carboxamides that can be employed as process intermediates are also disclosed. | 2010-11-04 |
20100280245 | PROCESS AND INTERMEDIATES FOR THE PREPARATION OF N-ACYLATED-4-ARYL BETA-AMINO ACID DERIVATIVES - A process for producing an enantiomerically enriched, pure or enriched and essentially pure compound of Formula I: | 2010-11-04 |