44th week of 2013 patent applcation highlights part 48 |
Patent application number | Title | Published |
20130288193 | APPARATUS AND SYSTEM FOR DENTAL MODELING - An apparatus and system is disclosed for dental modeling. The apparatus includes a first tray positioned opposite a second tray and a dearticulating hinge coupling the first tray to the second tray. The dearticulating hinge includes a first hinging element coupled to one of the first tray and the second tray and a second hinging element coupled to the other of the first tray and the second tray. At least one of the first hinging element and the second hinging element includes a disengaging element configured to engage a spur to uncouple the first hinging element from the second hinging element upon extending the first tray and the second tray beyond a predefined angle relative to one another. | 2013-10-31 |
20130288194 | FLUORIDE VARNISH - A tooth varnish that is free from pinus extracts, free of substantial undesired coloring agents, with a reduced viscosity, delivered in a user-friendly, flow-through, unit dose applicator and having improved fluoride release, uptake, and remineralization properties. | 2013-10-31 |
20130288195 | Nozzle for Blasting Liquid Detergents with Dispersed Abrasive Particles - For to avoid clogging from abrasive media, a nozzle contains an element for circular vortexing the passing jet of detergents in combination with a defined flexibility of its elements, which—together with a pulsating stream of media—causes vibrations, that constantly lead to peeling off adhering residues. | 2013-10-31 |
20130288196 | ERGONOMIC DENTAL TOOLS - A dental tool is disclosed that includes an operational unit, a neck region and a handle region, in which the neck region is S-shaped. The operational unit can further include a tongue retractor, a flap retractor or a combination thereof. A suction mechanism may be added for eliminating fluids. The neck region may further contain a lateral bend, a rotation of the working end or both. The proximal end of the handle region, opposite the operational unit, may further include any useful apparatus, such as a periosteal elevator or periosteal retractor. | 2013-10-31 |
20130288197 | DENTAL FILING TOOL HANDLE - An improved handle for a dental filing tool, the tool having an arcuate handle with a horizontal bridge and opposed first and second vertical arms, the improvement including first and second sets of partial-cylindrical grip portions distributed along the outer surfaces of the first and second vertical arms, respectively, the grip portions aligned normal to the handle plane, the respective first and second sets defining convex outer grip profiles and concave front-back grip profiles. An improved handle may further include an embedded socket to receive a coupler for a dental driver. | 2013-10-31 |
20130288198 | HEALING ABUTMENT AND FINAL ABUTMENT FOR USE WITH DENTAL IMPLANT - Systems and methods of controlling an abutment when inserting or removing the abutment are disclosed. An improved dental abutment is presented that includes a tunnel whereby dental floss may be laced through to serve as a tether for retrieval of the abutment during attachment to or removal from a dental implant. | 2013-10-31 |
20130288199 | COMPOSITE REGENERATION MEMBRANE - A composite regeneration membrane is utilized for separating an alveolar bone tissue and a gum epithelium tissue. The composite regeneration membrane comprises a collagen resorbable layer and a titanium bendable layer. The collagen resorbable layer is utilized for transmitting material between the alveolar bone tissue and the gum epithelium tissue. The titanium bendable layer is located in the collagen resorbable layer for supporting the collagen resorbable layer. The titanium bendable layer also has a plurality of transmitting holes allowing the material transmitted by the collagen resorbable layer to pass through. | 2013-10-31 |
20130288200 | DENTAL IMPLANT WEDGES - A method for securing a dental implant within a dental bone cavity is disclosed. The method may include inserting a dental wedge into the dental bone cavity and allowing bone tissues to grow toward and at least partially surround the dental wedge. Dental implantation systems for implementing the method are also disclosed. The system can comprise a dental wedge adapted to be inserted into a dental bone cavity. | 2013-10-31 |
20130288201 | Bionic Tooth Implant, and Base and Sub-Root Thereof - The invention discloses a bionic tooth implant, comprising a main root and a basal platform, wherein the main root comprises a fixing root part positioned at the lower part thereof and a basal platform positioned at the upper part thereof; the bionic tooth implant also comprises at least one subsidiary root; the basal platform is mounted on the main root via the basal platform of the main root, wherein an inclined hole is provided on the basal platform; an inclined-direction hole communicated with the inclined hole is provided on the main root; the subsidiary root comprises the fixing root part positioned at the lower part thereof and a connected part positioned at the upper part thereof; the connected part is mounted in the inclined hole; the subsidiary root extends from the inclined-direction hole through the main root; and at least a part of the fixing root part is positioned at the outer part of the main root. As to the bionic tooth implant, after the main root is implanted into the jaw of the patient, the basal platform is directly inserted into the main root and then the matched installation between the main root and the basal platform is completed. The subsidiary root is directly screwed into the jaw and the whole implanting process of the bionic tooth implant is completed, without two-stage operation and the arrangement of the basal platform. The whole operation process is convenient and rapid. | 2013-10-31 |
20130288202 | SOFT TISSUE PRESERVATION TEMPORARY (SHELL) IMMEDIATE-IMPLANT ABUTMENT WITH BIOLOGICAL ACTIVE SURFACE - An immediate dental implant shell has outer, multiple zones for engaging a soft tissue socket left immediately after tooth extraction from a bone socket. The zones have combinations of different biologic agents, macro- or micro-geometric, or micro- or macro-morphology irregularities to better engage gingival sulcus, junctional epithelium and dento-gingival fiber zones of the soft tissue socket. The shell may also have various guide markings and projections to aide drilling of the implant hole in the bone socket. A dental implant is placed in the drilled implant hole before or after the shell has been placed in the soft tissue socket, and has an axis that is independent of the shell axis so the shell and implant both sit in optimum positions in their respective soft and bone sockets. | 2013-10-31 |
20130288203 | METHOD OF SIMULTANEOUSLY CLEANING AND WHITENING TEETH - A method for simultaneously cleaning and whitening teeth comprising the steps of: applying a conditioning composition to the teeth surface, applying an oxidizing composition to the teeth surface, applying a sealant composition to the teeth surface, cleaning the teeth surface, polishing the teeth surface and removing the condition compositions from the teeth. | 2013-10-31 |
20130288204 | Trigger Trainer - An insert is placed in the trigger guard between the front portion of the trigger guard and the trigger to reduce the size of the opening designed to accommodate the trigger finger and permit only a portion of the finger to be inserted for engaging the trigger, typically the outer tip area between the tip and the first joint of the finger. The training tool guides the trigger finger into the right position, establishing proper alignment of the finger to the trigger and increasing the probability that the probability that the trigger will be properly squeezed by promoting proper placement of the trigger finger each time the trigger is engaged. After repeated use with the trigger guard, the placement of the finger will become automatic. | 2013-10-31 |
20130288205 | Rifle Scope and Method of Providing Embedded Training - A method includes providing a visual representation of a targeting environment to a display of a rifle scope, where the visual representation includes a target and a reticle. The method further includes receiving a trigger pull signal at a processor coupled to the display, determining an impact location of a virtual shot in response to receiving the trigger pull signal, and dynamically adjusting the target within the visual representation in response to determining the impact location. | 2013-10-31 |
20130288206 | DRIVING EVALUATION SYSTEM AND VEHICLE-MOUNTED DEVICE - A driving evaluation system that divides a traveling route of a vehicle into a plurality of sections and evaluates the driving of a driver of the vehicle includes: a driving data acquiring unit that acquires driving data of the driver for each section; a determining unit that determines whether the driving data acquired by the driving data acquiring unit satisfies the evaluation conditions set to each section; and an upload unit that uploads the driving data to a center which evaluates driving when the determining unit determines that the driving data satisfies the evaluation conditions. | 2013-10-31 |
20130288207 | Method of Preparing Letter Art - A method of creating and manipulating Letter Art, allowing a user to create unique Letter Art by individually changing visual elements of the letters. | 2013-10-31 |
20130288208 | DIETING SUPPORT SYSTEM AND DIETING SUPPORT METHOD - A dieting support system includes a function that detects a component of biogas and that measures concentration of the biogas, a function that accumulates and analyzes the measured result, and a function that determines suitable timing for taking a meal or suitable timing for doing exercise, depending on the analyzed result. | 2013-10-31 |
20130288209 | BOOKLET ASSEMBLY WITH GRID BOX AND METHOD TO HELP CHILDREN TO WRITE AND CREATE - The current invention discloses a grid box that may be printed in a booklet to help children to learn writing, improve handwriting, and create their own content. The grid box has four parallel lines defining three spaces that may be used for standardized handwriting of English and Spanish words and letters. The middle space of the grid box is shaded to facilitate the process to standardize handwriting. The grid boxes are preferably printed in a booklet assembly having two or more booklets stacked together. These booklets have different lengths and widths, while the bigger booklets are positioned beneath the smaller booklets, making a stepped arrangement. With picturing pasting sections and leading texts, the children learning to write may be prompted to handwrite letters and words in the grid boxes while completing a story. | 2013-10-31 |
20130288210 | INTEGRATED MAINTENANCE MANAGEMENT SYSTEM - A semi-automated maintenance management system instructs a technician to disassemble a component into parts, compare each part to a reference entry and identify any discrepancies between the part and the reference entry, repair or replace the component according to instructions automatically provided for the discrepancy when a known discrepancy is found, create a disposition when an unknown discrepancy is found, and reassemble the component. | 2013-10-31 |
20130288211 | SYSTEMS AND METHODS FOR TRAINING A WELDING OPERATOR - A welding, plasma cutting, or heat induction system to train a welding operator. The system includes a display configured to show a prerecorded video selected from multiple prerecorded videos. The prerecorded videos correspond to a welding application, a plasma cutting application, a heat induction application, or some combination thereof. | 2013-10-31 |
20130288212 | System and A Method for Analyzing Non-verbal Cues and Rating a Digital Content - A system and a method for capturing and analyzing the non-verbal and behavioral cues of the users in a network is provided. The sensors present in the client device capture the user behavioral and sensory cues and analysis is performed to derive analytics for the particular event it corresponds to. | 2013-10-31 |
20130288213 | Method for training players and sportsmen - The invention relates to methods for training players and sportsmen. The technical result is an increase in the effectiveness of training. The method for training players and sportsmen with a piece of sports equipment on a pitch includes carrying out the training on a pitch that is provided with controllable dynamic lighting. The dynamic lighting is used to establish permitted zones in which the sportsman must be found, holding the piece of sports equipment. Further, the position, shape and area of the permitted zones are altered at random for the sportsman. The development of the sportsman's skill and the effectiveness of training are judged according to the sportsman's ability to stay in the permitted zones, holding the piece of sports equipment. | 2013-10-31 |
20130288214 | Method and System for Automatic Tool Position Determination for Minimally-Invasive Surgery Training - The present invention may be embodied as a method of minimally-invasive surgery (“MIS”) training using a video of an MIS comprising the steps of providing a processor, a display, and a first input device. The method comprises the step of processing the video using the processor to determine a location of the first surgical tool in each of the frames, determining whether the configuration of the first input device substantially corresponds to the location of the first surgical tool in each frame of the video while the video is displayed. The present invention may be embodied as a system for MIS training. The system comprises a processor, a communication device, and a first input device in communication with the processor. The processor is programmed perform any or all of the described disclosed methods. | 2013-10-31 |
20130288215 | METHODS FOR USING VIRTUAL PATIENT MEDICAL DATA IN EDUCATION, DIAGNOSIS AND TREATMENT - Systems, methods and apparatuses for generating and using representations of individual or aggregate human medical data. | 2013-10-31 |
20130288216 | Simulant with Vascular Element Mechanically Responsive to a Tourniquet - A medical simulant applicable to training personnel in the treatment of a traumatic injury is presented. The simulant replicates the appearance of a body part and is mechanically responsive to externally applied pressure so as to mimic the response of a vascular element when a tourniquet or the like is applied to the body part. The simulant includes a compressible body, a structure, a compressible tube, and a pair of plates. The compressible body replicates an arm, a leg, or another body region. The structure replicates an injury, either penetrating or non-penetrating, and is disposed along the compressible body. The compressible tube replicates a vascular element. The plates are separately disposed within the compressible body about the compressible tube. The plates are configured to deform the compressible tube so as to interrupt flow of a liquid simulating blood therein when a compressive force is applied onto the compressible body by a tourniquet or the like. | 2013-10-31 |
20130288217 | SURGICAL SIMULATION DEVICE AND ASSEMBLY - A system for simulating a surgical procedure, which includes a housing covering an anatomical model. The model is made up of simulated tissue supported on a base assembly that allows pivoting and rotation of the simulated tissue. The simulated tissue includes a portion that represents soft tissue, such as dermal tissue, muscle, connective tissue and the like, and a portion that represents hard tissue, such as osseous tissue. The housing includes apertures through which a surgical instrument may be inserted for simulating a procedure on the simulated tissue. Cannulas may be set within the apertures. | 2013-10-31 |
20130288218 | CARDIAC MODEL FOR SIMULATING MEDICAL PROCEDURES - A resilient model of a heart's atria and associated vasculature is disclosed. The model is generated from CT scans of patients' with varying cardiac anatomies. The model is connected to a temperature-controlled fluid reservoir and a pump that periodically circulates fluid through the cardiac model. The model provides a visual indication of temperature change. The model may be used to simulate endocardial procedures such as pulmonary vein isolation for treatment of atrial fibrillation. | 2013-10-31 |
20130288219 | Providing Intelligent Inquiries In Question Answer Systems - A method, a system and a computer program product for selecting a further inquiry for a user to clarify a request for information from the user. One or more candidate answers to the request for information from the user are determined, and a score value is generated for each of one or more characteristics of each candidate answer, where at least one characteristic is associated with an inquiry for the user to clarify the request for information. A characteristic associated with an inquiry is determined that includes score values providing the greatest potential adjustment for the candidate answers in response to a clarification of the request for information, and the inquiry is selected that is associated with the determined characteristic for presentation to the user. | 2013-10-31 |
20130288220 | Evaluation and Assessment System - An evaluation system for detecting an anomalous response to a particular question from a plurality of questions is described. For each of the plurality of questions, data relating to a score, a trainee's confidence level in his response, and the elapsed time are stored. An anomaly processor processes the score, confidence level and elapsed time data for a set of questions taken from the plurality of questions. An output is produced indicating whether or not an anomalous response to a particular question is detected, which can be used by a computerized training system to determine whether or not the trainee passes the assessment. Where the candidate has passed the test, the processor determines an interval over which the candidate is deemed to retain a competent level of understanding of the topic. A timing unit may be provided for outputting a trigger signal when the interval has elapsed. | 2013-10-31 |
20130288221 | COMPUTING DEVICE-BASED EDUCATIONAL CONTENT DELIVERY SYSTEM - Systems, methods, and devices relating to the delivery of educational content to a user's computing device. An application for use with mobile computing devices or with computers is first downloaded by a user. Data related to a complete educational course is downloaded and installed on the user's computing device. When launched, the application provides the user with the educational content using voice enabled avatars. The educational content is designed to last up to 15 minutes to be delivered to the user. | 2013-10-31 |
20130288222 | SYSTEMS AND METHODS TO CUSTOMIZE STUDENT INSTRUCTION - A computer implemented systems and methods for determining an action for a user within a learning domain are disclosed, some embodiments of the methods comprise defining an initial learning model of a learning domain, determining an initial user state of the user, determining an initial user action from at least one learning domain action with the initial learning model, receiving a user observation of the user after the user executes the initial user action, determining an updated user state with the initial learning model given the updated user observation and determining a subsequent user action from the at least one learning domain action. Some embodiments utilize a Partially Observable Markov Model (POMDP) as the learning model. | 2013-10-31 |
20130288223 | Stimulating Learning Through Exercise - An exercise system stimulates the learning and memory of a user by detecting a stress level of the user with one or more biometric sensor devices, determining that the user's stress level is within a stress zone that is suitable for memory retention by the user, and presenting educational content to the user at one or more output devices. | 2013-10-31 |
20130288224 | Display Device and Method - The display device and method uses a computer display device or “pad” mounted in a frame and positioned to be visible to observers. The computer device is programmed to display user-selected messages for user-selected time periods. Preferably, the frame is displayed in the seats behind the front seats of a motor vehicle so that the passengers can be given lessons to view for selected lengths of time to facilitate learning and memorization, and to keep the passengers occupied. The frame structure allows lesson cards and handwritten messages to be displayed when the computer device is absent from the frame. | 2013-10-31 |
20130288225 | METHOD FOR SEPARATING WHOLE BLOOD - A method of separating blood by providing a horizontal substrate having a plurality of oxygen plasma-treated polypropylene pillars extending from the surface of a polypropylene film, depositing a whole blood sample on an upper surface of the substrate, collecting red blood cells on the upper surface of the pillars and permitting remaining components of said whole blood sample to flow downward and through the pillars. | 2013-10-31 |
20130288226 | APPARATUS FOR SEPARATING CELLS USING MAGNETIC FORCE AND CELL SEPARATION METHOD USING THE SAME - An apparatus for separating cells using magnetic force includes: a separation channel portion including ferromagnetic particles, and provided with a flow path through which a cell fluid containing a plurality of cells having at least one of diamagnetic and paramagnetic properties; and a magnetic field controller that generates a magnetic field within the flow path so that the cells in the cell fluid flow within the flow path and are separated by height by a magnetic field. Accordingly, there are provided an apparatus for separating cells using magnetic force and a cell separation method using the same, by which cells can be easily separated using magnetic force. | 2013-10-31 |
20130288227 | METHODS AND COMPOSITIONS FOR CELL SEPARATION OF BLOOD TISSUES - This document provides compositions and methods for cell separation. These reagents and techniques specifically agglutinate cells via surface antigen recognition and can be used to recover rare cell types in high yield. | 2013-10-31 |
20130288228 | METHODS AND APPARATUSES FOR CULTIVATING PHOTOTROPIC MICROORGANISMS - Method and apparatus for biomass cultivation (preferably using algae) incorporating photo bio-reactor (PBR) technology coupled with a heat sink to increase energy efficiency. An external PBR array is coupled to an indoor storage tank system with a volume equal to or greater than the volume of the PBR array. A controller can be used to optimize the growth of biomass by optimizing three key growth parameters: exposure to sunlight, temperature and nutrients. The indoor tank system serves as a reservoir where algae can be protected from harsh ambient conditions, minimizing the cost of energy for heating and cooling that would normally be incurred to accommodate ambient temperature swings caused by weather if the biomass is always stored in an outdoor PBR array. During cold winter nights, the biomass can be brought indoors to conserve thermal energy. | 2013-10-31 |
20130288229 | METHOD FOR DETECTION, DIFFERENTIATION AND QUANTIFICATION OF T CELL POPULATIONS BY WAY OF REVERSE TRANSCRIPTION QUANTITATIVE REAL TIME PCR (RT-qPCR) TECHNOLOGY - The present invention relates to a method for detection, differentiation and quantification of T cell populations, comprising the following steps a) contacting a first aliquot of a body fluid of an individual with at least one antigen, wherein the body fluid contains antigen presenting cells (APC) and T cells, b) incubating the first aliquot with at least one antigen for a certain period of time, c) detection and differentiation of the T cell population by detecting in the first aliquot and in a second aliquot of the body fluid of the individual, which has not been incubated with the at least one antigen, at least a first marker of the APC induced by T cells in a specific T cell population using reverse transcription quantitative real time-time polymerase chain reaction (RT-qPCR), and d) detection and quantification of the T cell population by determining the ratio of the detected marker of the APC of the first aliquot to the second aliquot as well as a kit for performing the method. | 2013-10-31 |
20130288230 | Method for identification of a natural biopolymer - The invention presents a method of identifying natural biopolymer—a protein, DNA, RNA in biological fluids and environmental objects, which is based only on the structure of the biopolymer and does not require pathogen genome sequencing, or animals vaccination by biopolymer-antigen. For this purpose the biopolymer itself is taken—a protein, DNA, or RNA, that is fragmented with enzyme to oligomer fragments—a mixture of oligopeptides, oligonucleotides DNA mixture, mixture of RNA oligonucleotides, without dividing the mixture into individual components, then carboxylation of structure in oligomer components is performed by acylation or alkylation. | 2013-10-31 |
20130288231 | UNIVERSAL MULTI-VARIANT DETECTION SYSTEM - The present invention provides a method to diagnostically detect the variants of a given pathogen, such as HIV, hepatitis C, hepatitis B (HBV), Parvovirus B19, etc., with the use of a single detection probe. | 2013-10-31 |
20130288232 | FAST THERMO-OPTICAL PARTICLE CHARACTERISATION - The present invention relates to a method and an apparatus for a fast thermo-optical characterisation of particles. In particular, the present invention relates to a method and a device to measure the stability of (bio)molecules, the interaction of molecules, in particular biomolecules, with, e.g. further (bio)molecules, particularly modified (bio)molecules, particles, beads, and/or the determination of the length/size (e.g. hydrodynamic radius) of individual (bio)molecules, particles, beads and/or the determination of length/size (e.g. hydrodynamic radius). | 2013-10-31 |
20130288233 | Selective Reaction Monitoring (SRM) Derived Protein Profiles for Cancer and other Pathologic Entities - The invention relates to a method of detecting and quantifying small peptides derived from proteins from a range of different clinical samples using the Selective Reaction Monitoring (SRM) profiling technique. By targeting these unique peptides which specifically identify particular proteins, the present invention enables multiple samples to be run in a multiplexed fashion in order to identify, diagnose, quantitate and profile a full range of benign and pathologic entities, including but not limited to, the complete range of cancers and the spectrum of inflammatory diseases, including inflammatory cell typing and bone marrow cell typing. The SRM assay is capable of performing clinical blood typing and it can also act as a diagnostic test to identify women at highest risk for cervical cancer base on Human Papillomavirus (HPV) testing. | 2013-10-31 |
20130288234 | DEVICE FOR PREPARING A SAMPLE - The invention provides a device for preparing a fluid sample, including but not limited to a sample comprising genomic DNA. | 2013-10-31 |
20130288235 | METHOD OF DETERMINING THE NUCLEOTIDE SEQUENCE OF OLIGONUCLEOTIDES AND DNA MOLECULES - The present invention relates to a novel method for analyzing nucleic acid sequences based on real-time detection of DNA polymerase-catalyzed incorporation of each of the four nucleotide bases, supplied individually and serially in a microfluidic system, to a reaction cell containing a template system comprising a DNA fragment of unknown sequence and an oligonucleotide primer. Incorporation of a nucleotide base into the template system can be detected by any of a variety of methods including but not limited to fluorescence and chemiluminescence detection. Alternatively, microcalorimetic detection of the heat generated by the incorporation of a nucleotide into the extending template system using thermopile, thermistor and refractive index measurements can be used to detect extension reactions. | 2013-10-31 |
20130288236 | WT1 MUTATIONS FOR PROGNOSIS OF MYELOPROLIFERATIVE DISORDERS - The invention provides methods for determining the prognosis of a patient diagnosed with a leukemia, including B-cell chronic lymphocytic leukemia, by measuring mutations of the WT1 gene in a biological sample. The invention also relates to the diagnosis of leukemia, including B-cell chronic lymphocytic leukemia. | 2013-10-31 |
20130288237 | QUANTIFICATION OF ADAPTIVE IMMUNE CELL GENOMES IN A COMPLEX MIXTURE OF CELLS - Compositions and methods are described for highly sensitive quantification of the relative representation of DNA from adaptive immune cells (e.g., T and/or B lymphocytes) in DNA extracted from complex mixtures of cells that include cells which are not adaptive immune cells. Included are methods for determining the relative presence in a tumor of tumor infiltrating lymphocytes (TIL), the relative presence of lymphocytes infiltrating a somatic tissue that is the target of an autoimmune disease, and the relative presence of lymphocytes infiltrating a transplanted organ. | 2013-10-31 |
20130288238 | Methods and Compositions for Detecting Serotypes of Chlamydia trachomatis Capable of Causing Lymphogranuloma Venereum - Disclosed are methods and compositions for conducting assays utilizing real-time polymerase chain reactions (“PCRs”) in detection of serotypes L I, L II, and L III, but not stereotype B, of | 2013-10-31 |
20130288239 | BIOMARKER FOR HUMAN LIVER CANCER - The disclosure relates to a method for determining incidence of liver cancer in a subject, including detecting methylation level or expression level of one microRNA miR-129-2 in a bio-sample from the subject. In the case that the methylation level of the microRNA in the bio-sample is higher or the expression level of the microRNA in the bio-sample is lower relative to that of the corresponding microRNA in a control sample, indicates that the subject is predisposed to or afflicted with liver cancer. | 2013-10-31 |
20130288240 | ALK AND ROS KINASE IN CANCER - A method for identifying a patient with cancer or suspected of having cancer as a patient likely to respond to an ALK- and/or ROS-inhibiting therapeutic is provided, the method comprising: contacting a biological sample from a patient with a first reagent that specifically binds a polypeptide having ROS kinase activity and a second reagent that specifically binds to a polypeptide having ALK kinase activity, and detecting whether the first reagent or the second reagent specifically binds to the biological sample, wherein detection of binding of either the first reagent or the second reagent to the biological sample identifies the patient as a patient likely to respond to an ALK-inhibiting and/or ROS-inhibiting therapeutic. | 2013-10-31 |
20130288241 | COMPOSITIONS AND METHODS FOR DETECTING A NEOPLASIA - The invention provides compositions and methods for detecting a neoplasia (e.g., pancreatic cancer, lung cancer, colon cancer) in a subject sample (e.g., serum, blood, plasma, tissue). In particular embodiments, the invention provides methods for detecting BNC1 and ADAMTS1 promoter methylation in circulating DNA in serum. | 2013-10-31 |
20130288242 | DETERMINATION OF FETAL ANEUPLOIDY BY QUANTIFICATION OF GENOMIC DNA FROM MIXED SAMPLES - The present invention provides systems, apparatuses, and methods to detect the presence of fetal cells when mixed with a population of maternal cells in a sample and to test fetal abnormalities, i.e. aneuploidy. In addition, the present invention provides methods to determine when there are insufficient fetal cells for a determination and report a non-informative case. The present invention involves quantifying regions of genomic DNA from a mixed sample. More particularly the invention involves quantifying DNA polymorphisms from the mixed sample. | 2013-10-31 |
20130288243 | Mitochondrial DNA deletion between about residues 12317-16254 for use in the detection of cancer - The present invention relates to methods for predicting, diagnosing and monitoring cancer. The methods comprise obtaining biological samples, extracting mitochondrial DNA (mtDNA) from the samples, quantifying a mtDNA mutation in the sample and comparing the level of the mtDNA mutation present in the sample with a reference value The methods of the invention may also be effective in screening for new therapeutic agents and treatment regimes Further, said methods may be also be useful for monitoring the response of a subject to a preventative or therapeutic treatment. | 2013-10-31 |
20130288244 | METHODS AND PROCESSES FOR NON-INVASIVE ASSESSMENT OF GENETIC VARIATIONS - Provided herein are methods, processes and apparatuses for non-invasive assessment of genetic variations. | 2013-10-31 |
20130288245 | MODIFIED RNASE H ENZYMES AND THEIR USES - The invention provides a provides improvements to assays that employ RNase H cleavage for biological applications related to nucleic acid amplification and detection, where the RNase H has been reversibly inactivated. | 2013-10-31 |
20130288246 | COMPOSITIONS, METHODS, AND KITS FOR ANALYZING DNA METHYLATION - Compositions, methods, and kits for reducing strand amplification bias using bisulfite treated gDNA are provided. Methods for detecting and for quantitating the amplified bisulfite treated gDNA and inferring the presence, absence, and/or degree of methylation of target cytosine(s) in the gDNA are also provided. Such methods typically employ tailed first primer pairs, which can, but need not comprise nucleotide analogs, and optionally second primer pairs. | 2013-10-31 |
20130288247 | NOVEL DNA HYPERMETHYLATION DIAGNOSTIC BIOMARKERS FOR COLORECTAL CANCER - The present invention relates to the field of cancer. More specifically, the present invention relates to the use of biomarkers to detect colorectal cancer. In one aspect, the present invention provides methods for qualifying colorectal cancer status including, but not limited to, diagnosis, prognosis, and risk stratification, in patients. In one embodiment, a method for diagnosing colorectal cancer (CRC) in a patient comprises the steps of (a) collecting a sample from the patient; (b) measuring the methylation levels of one or more biomarkers in the sample collected from the patient; and (c) comparing the methylation levels of the one or more biomarkers with predefined methylation levels of the same biomarkers that correlate to a patient having CRC and predefined methylation levels of the same biomarkers that correlate to a patient not having CRC, wherein a correlation to one of the predefined methylation levels provides the diagnosis. | 2013-10-31 |
20130288248 | CANCER STEM CELL MASS AND PROCESS FOR PRODUCTION THEREOF - The purpose of the present invention is to provide: a cancer stem cell mass from which cells incapable of forming cancer are substantially removed and which has a characteristic property of reproducing a layered structure of a cancer tissue; a process for producing the cancer stem cell mass; and use of the cancer stem cell mass. For achieving the purpose, the present inventors grew a human cancer tissue repeatedly in a NOG mouse, separated cancer cells from the grown cancer tissue, and made a comparison of various cancer cell culture processes with each other. As a result, a cancer stem cell composition which is homogeneous and is substantially free of the coexistence of cells capable of forming cancer and cells incapable of forming cancer in a mixed state can be produced successively by employing an attached culture process using a serum-free stem cell culture medium rather than a generally employed floating culture process, and consequently the present invention has been accomplished. | 2013-10-31 |
20130288249 | Dynamic Range Methods - The present invention relates to methods for detecting and quantifying an analyte in a sample, principally in proximity probe assays, and in particular to an improvement in such methods to extend the dynamic range of detection, which is particularly advantageous for the detection and quantification of an analyte where the concentration range of the analyte in said sample is unknown and/or the range is likely to be broad, said method comprising: (i) contacting said sample with at least a pair of proximity probes each comprising a proteinaceous target-binding domain coupled to a nucleic acid domain such that said nucleic acid domains may be allowed to interact directly or indirectly when the proximity probes have bound in proximity to their respective target, said target being either the analyte or a binding partner for the analyte; (ii) further contacting said sample with at least one set of markers which function to extend the dynamic range of detection of the method, wherein said set comprises at least two markers, wherein each marker is a nucleic acid molecule comprising a binding domain and a reporter domain which gives rise to a detectable signal, and each marker: (a) is capable of interacting either with said nucleic acid domains to form a nucleic acid molecule from which a detectable signal is generated, or with a nucleic acid molecule generated by interaction of said domains; (b) cannot interact with said nucleic acid domains simultaneously with another marker in the set; (c) generates a signal that is distinguishable from the signal of another marker in the set; and (d) is present in an amount capable of detecting the analyte at a range of concentrations that differs from the range of concentrations detectable by other markers; (ii) allowing said markers to interact with said nucleic acid domains or said generated nucleic acid molecule; and (iii) detecting said signal. | 2013-10-31 |
20130288250 | SIGNATURES OF CLINICAL OUTCOME IN GASTRO INTESTINAL STROMAL TUMORS AND METHOD OF TREATMENT OF GASTROINTESTINAL STROMAL TUMORS - A method for in vitro predicting survival and/or metastatic outcome of gastrointestinal stromal tumors (GISTs), characterized in that it comprises the measure of the level, in a patient-derived biological sample of GIST, of a pool of polypeptides or polynucleotides consisting in Aurora kinase A (AURKA); a kit for the in vitro prediction of the survival outcome of a patient suffering from GIST, and/or the development of metastases in a patient treated for or suffering from GIST, and/or the prediction of the efficacy of a treatment for GIST, characterized in that it comprises means for detecting and/or quantify, in a sample, AURKA expression or level, and means for the calculation of the GI; and a method for screening for compounds for the use in the treatment of GISTs and to an AURKA inhibitor for its use in the treatment of GISTs. | 2013-10-31 |
20130288251 | LACTOCOCCUS CRISPR-CAS SEQUENCES - The present invention relates to a nucleic acid comprising a | 2013-10-31 |
20130288252 | ASSAY SYSTEMS FOR GENETIC ANALYSIS - The present invention provides assay systems and methods for detection of copy number variation at one or more loci and polymorphism detection at one or more loci in a mixed sample from an individual. | 2013-10-31 |
20130288253 | Particles for Detecting Intracellular Targets - Methods describing the use of nanoparticles modified with binding moieties are provided. | 2013-10-31 |
20130288254 | Droplet Actuator and Droplet-Based Techniques - The invention is directed to certain droplet actuated molecular techniques. In one embodiment, the invention provides droplet actuator methods for detection of single nucleotide polymorphisms (SNPs) in a DNA sequence using digital microfluidics, including droplet actuator-based sample preparation and SNP analysis. In another embodiment, the invention provides droplet actuator devices and methods for providing integrated sample preparation and multiplexed detection of an infectious agent, such as HIV. In yet another embodiment, the invention provides droplet actuator devices and techniques for PCR amplification and detection of specific nucleic acid sequences using digital microfluidics, including droplet actuator-based sample preparation and target nucleic acid analysis. In yet another embodiment the invention provides methods for performing hot-start PCR on a droplet actuator. In yet another embodiment, the method of the invention combines PCR amplification with pyrosequencing to investigate specific sequences. | 2013-10-31 |
20130288255 | BIOMARKERS OF AGEING - The present invention relates to methods to predict the functional decline of a patient (preferable an elder patient). | 2013-10-31 |
20130288256 | METHODS AND COMPOSITIONS FOR TOPOISOMERASE I MODULATED TUMOR SUPPRESSION - Disclosed herein are methods and compositions for determining the sensitivity or enhancing the sensitivity of cells to the effects of topoisomerase I inhibitors. Also disclosed are methods and compositions for inducing cell death, apoptosis and/or growth arrest which may be used for tumor suppression. | 2013-10-31 |
20130288257 | DISPOSABLE THERMAL IN-VITRO DIAGNOSTIC APPARATUS AND METHOD OF CONDUCTING AN IN-VITRO DIAGNOSTIC TEST - A portable, disposable in-vitro diagnostic apparatus and method of performing an in-vitro diagnostic test is provided. The apparatus includes a body configured to be hand held. The body has a reaction medium supply chamber configured in selective fluid communication with a reaction chamber via a fluid conveying channel. The reaction chamber is located beneath a sample reaction chamber. The reaction medium supply chamber contains a reaction fluid therein and the reaction chamber contains a thermal reaction medium therein. The reaction fluid is selectively reactive with the thermal reaction medium to produce one of an endothermic or exothermic reaction beneath the sample reaction chamber. | 2013-10-31 |
20130288258 | METHODS AND COMPOSITIONS FOR DETECTING COLORECTAL CANCER USING MICRO RNAs - Methods of detecting or predicting the presence of CRC based on the amounts of particular miRNAs in plasma or tissue are described. | 2013-10-31 |
20130288259 | AUTOMATED NUCLEIC ACID PROCESSOR AND AUTOMATED NUCLEIC ACID PROCESSING METHOD USING MULTI FUNCTION DISPENSING UNIT - In relation to an automated nucleic acid processor and an automated nucleic acid processing method using a multi function dispensing unit, processing involving extraction and amplification of the nucleic acid, can be consistently, quickly and efficiently conducted at a low cost with the use of a multi function dispensing unit, while saving user's trouble without expanding the scale of the device. The multi function dispensing unit includes: a nozzle head provided with a suction-discharge mechanism and nozzles detachably provided with dispensing tips; a container group having, at the very least housing parts for liquids and reaction containers for housing an amplification solution; a transfer mechanism that makes an interval between the nozzles and the container group relatively movable; a temperature controller whereby temperature control of the interior of the reaction vessels is possible; sealing liquids and/or sealing lids that are transportable to the reaction vessels using the nozzles, and which make the amplification solutions housed in the reaction vessels sealable within the reaction vessels; and a sealing control part that controls the suction-discharge mechanism or the transfer mechanism, such that the sealing liquid and/or the sealing lids seal the amplification solution within the reaction vessels when the housing of the amplification solution in the reaction vessels is completed. | 2013-10-31 |
20130288260 | Compositions and Methods For Enhancing the Biological Response to Chemical Agents and Physical Stimuli - The present invention relates to compositions and methods configured to deliver a stimulus (e.g., a therapeutic agent or a therapeutically beneficial signal) to a cell, tissue, organ, or organism. The stimulus is applied at least twice, and the first and second applications are separated by a rest period in which no further stimulus is actively applied. The rest period is of a duration (e.g., about 1-6 hours) sufficient to provoke an enhanced response to the second stimulus. | 2013-10-31 |
20130288261 | PROBIOTICS AND METHODS OF OBTAINING SAME - This disclosure describes novel probiotics, and also describes novel methods by which such probiotics can be obtained. | 2013-10-31 |
20130288262 | Multiple Mesodermal Lineage Differentiation Potentials for Adipose Tissue-Derived Stromal Cells and Uses Thereof - The invention relates to methods and compositions for the differentiation of stromal cells from adipose tissue into hematopoietic supporting stromal cells and myocytes of both the skeletal and smooth muscle type. The cells produced by the methods are useful in providing a source of fully differentiated and functional cells for research, transplantation and development of tissue engineering products for the treatment of human diseases and traumatic tissue injury repair. | 2013-10-31 |
20130288263 | Device For Detection Of Target Molecules And Uses Thereof - Devices and methods for the detection of target molecules are disclosed. Devices and methods for detecting food-borne target molecules are also disclosed. | 2013-10-31 |
20130288264 | Development of a New Isolation Method with Higher Selectivity and Efficiency - A sample extraction method with improved sensitivity for capture of trace amounts of target by utilizing a target-specific enzyme, and covalently bonding the target for capture and immobilization on an activated surface. | 2013-10-31 |
20130288265 | UBIQUITIN LIGASE ASSAYS AND RELATED REAGENTS - The disclosure provides, inter alia, methods and reagents for use in measuring the attachment of ubiquitin and ubiquitin-like proteins to a target protein, particularly an E3 protein. | 2013-10-31 |
20130288266 | DETECTION OF A POSTTRANSLATIONALLY MODIFIED POLYPEPTIDE BY A BI-VALENT BINDING AGENT - A bi-valent binding agent having a first monovalent binder that binds to a polypeptide epitope of a target polypeptide, a second monovalent binder that binds to a posttranslational polypeptide modification on the target polypeptide and a linker. Further disclosed are methods for the detection of a posttranslationally modified target polypeptide, for making the disclosed bi-valent binding agent, and for use of the disclosed bi-valent binding agent in histological staining procedures. | 2013-10-31 |
20130288267 | DETECTION OF A POLYPEPTIDE DIMER BY A BIVALENT BINDING AGENT - A bivalent binding agent, capable of binding a polypeptide dimer, consisting of two monovalent binders linked to each other via a linker, the first monovalent binder binds an epitope of a first target polypeptide comprised in said dimer and the second monovalent binder binds to an epitope of a second target polypeptide comprised in said dimer. Each monovalent binder has a Kdiss in the range of 5×10 | 2013-10-31 |
20130288268 | SULFENIC ACID-REACTIVE COMPOUNDS AND THEIR METHODS OF SYNTHESIS AND USE IN DETECTION OR ISOLATION OF SULFENIC ACID-CONTAINING COMPOUNDS - The present invention provides compounds of Formula I: | 2013-10-31 |
20130288269 | Biomarkers For Prediction Of Major Adverse Cardiac Events And Uses Thereof - The present invention relates to combinations of biomarkers and levels thereof that may be used, for example, in the determination of risk associated with the occurrence of a major adverse cardiac event (MACE) in a patient. | 2013-10-31 |
20130288270 | CHEMILUMINESCENT ENZYME ASSAY METHOD AND APPARATUS - A chemiluminescent enzyme immunoassay method for quantifying antigen or antibody using 1,1′-oxalyldiimidazole (ODI) derivative or 1,1′-oxalyldisodium benzoate (ODB) derivative chemiluminescence (CL) detection was developed. Also, various enzymes were quantified using ODI derivative or DOB derivative CL detection. Fluorescent compound formed from a substrate (non-fluorescent compound) through the enzyme assay methods emitted CL when the fluorescent compound received energy from high-energy intermediate formed in ODI derivative or ODB derivative CL reaction. | 2013-10-31 |
20130288271 | METHODS FOR DETECTING ALLOSTERIC MODULATORS OF PROTEIN - The present invention discloses, inter alia, methods for labeling a target protein with an SHG-active probe for detection by second harmonic or sum-frequency generation in order to identify agents which bind to an allosteric site on the target protein thereby altering its structural conformation | 2013-10-31 |
20130288272 | LUNG CANCER DIFFERENTIAL MARKER - An object of the present invention is to develop and provide a lung cancer differential marker with which lung cancer can be diagnosed conveniently and highly sensitively without depending only on increase or decrease in protein expression level between cancer patients and healthy persons. Another object of the present invention is to develop and provide a glycan marker capable of distinguishing histological types of lung cancer. Of serum glycoproteins, glycopeptide and glycoprotein groups whose glycan structures were altered specifically in lung cancer cell culture supernatants were identified, and they are provided as lung cancer differential markers. | 2013-10-31 |
20130288273 | Method for Detecting Cancer Cell - A method for detecting a cancer cell, including: contacting in vitro a peripheral blood-containing sample including test cells and a labeling substance; allowing the test cells to incorporate the labeling substance to label the test cells; and detecting, as a cancer cell, a cell showing a higher degree of labeling with the labeling substance than that shown by a normal cell in the peripheral blood-containing sample. | 2013-10-31 |
20130288274 | RECOMBINANT DEAMIDATED GLIADIN ANTIGEN - The present invention provides a method for determining whether a subject is suffering from celiac disease by contacting a sample of bodily fluid from the subject, with an antigen formed from a hexamer of a gliadin fusion protein immobilized on a solid support. The gliadin fusion protein of the antigen includes a recombinant deamidated gliadin linked to a tag such as Glutathione-S transferase (GST) protein. The antigen is prepared by immobilizing the gliadin fusion protein on the solid support. The antigen can further include tissue Transglutaminase (tTG) cross-linked to the gliadin fusion protein. When tTG is present, the tTG and recombinant deamidated gliadin are mixed together prior to immobilization to the solid phase. | 2013-10-31 |
20130288275 | COMPOSITIONS AND METHODS FOR DETECTING ACETYLATED SUMO PROTEINS - The invention is directed to methods of using antibodies or antibody fragments that specifically bind to an acetylation domain of a small ubiquitin-like modifier protein (SUMO protein) when the acetylation domain is at least partially acetylated. The invention is also directed towards antibodies or antibody fragments that specifically bind to an acetylation domain of a small ubiquitin-like modifier protein (SUMO protein) when the acetylation domain is at least partially acetylated. | 2013-10-31 |
20130288276 | METHOD FOR PREDICTION OF PROGNOSIS OF SEPSIS - Disclosed is a prediction method for the prognosis of sepsis comprising measuring an sCD14-ST level in a sample. sCD14-ST, to be measured in the present invention, is a marker superior to procalcitonin, known as a marker to predict the prognosis in sepsis patients. | 2013-10-31 |
20130288277 | IMMUNOASSAY OF COFILIN 1 PROTEIN - An object of the present invention is to realize an antibody or a fragment thereof specifically recognizing a cofilin 1 protein, and a method for detecting and testing gastrointestinal cancer with high detection performance, which comprises performing immunoassay of the cofilin 1 protein using the antibody or a fragment thereof. An immunoassay of cofilin 1 protein is characterized by measuring cofilin 1 or a fragment thereof in a sample using 2 or more types of anti-cofilin 1 monoclonal antibody or fragments thereof specifically recognizing different peptide regions in the amino acid sequence constituting the cofilin 1 protein. | 2013-10-31 |
20130288278 | SCREENING METHOD USING GELATINASE-MEDIATED EphA4 CLEAVAGE REACTION AS AN INDICATOR - The object of the present invention is to provide a method for screening a substance that affects gelatinase-mediated EphA4 processing. The present invention provides a method for screening a substance that affects gelatinase-mediated EphA4 processing, which comprises the steps of: (a) allowing a first biological composition containing gelatinase or a biologically active fragment thereof to be contacted with a second biological composition containing EphA4 in the presence and absence of a candidate substance; (b) measuring the presence or amount of the EphA4 ectodomain and/or endodomain fragment; and (c) selecting the candidate substance as a substance that affects gelatinase-mediated EphA4 processing if the results of the step (b) measured in the presence of the candidate substance are changed in comparison with the results of the step (b) measured in the absence of the candidate substance. | 2013-10-31 |
20130288279 | SPECIFIC A1AT MONOCLONAL ANTIBODIES FOR DETECTION OF ENDOMETRIOSIS - Provided herein are monoclonal antibodies with a high binding affinity to isoforms of alpha 1-antitrypsin (A1AT), hybridoma cells producing the same, and their uses in diagnosing and/or detecting endometriosis from a serum sample of a subject suspicious of having endometriosis or a subject under health examination. | 2013-10-31 |
20130288280 | ALZHEIMER'S DIAGNOSIS - Evaluation of VLP-1 levels in combination with at least one of amyloid-β peptide (Aβ), hyperphosphorylated tau (pTau) or total tau (tTau) levels in samples of biological fluid improves the accuracy of diagnosis of Alzheimer's disease. | 2013-10-31 |
20130288281 | METHOD AND KIT FOR QUANTITATIVELY DETERMINING SMALL, DENSE LDL CHOLESTEROL - A method for fractional measurement of small, dense LDL, which is adaptable for an autoanalyzer, and a reagent for measurement, are provided, making it possible to conduct rapid and convenient analysis with good sensitivity without pretreatment of a specimen. The method for quantitatively determining small, dense LDL cholesterol in a sample comprises the steps of:
| 2013-10-31 |
20130288282 | Temperature-Adjusted Analyte Determination For Biosensor Systems - A biosensor system determines analyte concentration from an output signal generated by an oxidation/reduction reaction of the analyte. The biosensor system adjusts a correlation for determining analyte concentrations from output signals at one temperature to determining analyte concentrations from output signals at other temperatures. The temperature-adjusted correlation between analyte concentrations and output signals at a reference temperature may be used to determine analyte concentrations from output signals at a sample temperature. | 2013-10-31 |
20130288283 | METHOD FOR MEASURING COMPONENT TO BE MEASURED - The present invention provides a method for measuring a component to be measured in a sample, comprising converting the component to be measured in the sample into hydrogen peroxide and measuring the formed hydrogen peroxide in the presence of an α-keto acid using an oxidative-coloring chromogen. The present invention also provides a method for suppressing the influence of a peroxide on a method of converting a component to be measured in a sample into hydrogen peroxide and measuring the formed hydrogen peroxide using an oxidative-coloring chromogen, the suppression method comprising using an α-keto acid. The measuring method and the suppression method of the present invention using an α-keto acid suppress the influence of a peroxide to give an accurate measurement of the component to be measured in the sample. | 2013-10-31 |
20130288284 | METHODS AND COMPOSITIONS FOR CELL-PROLIFERATION-RELATED DISORDERS - Methods of treating and evaluating subjects having neoactive mutants of IDH (e.g., IDH1 or IDH2). | 2013-10-31 |
20130288285 | METHODS FOR PREDICTING CARDIAC TOXICITY - Methods are disclosed for determining whether organ toxicity, particularly cardiotoxicity, will occur in a patient selected for treatment with various kinase inhibitors, such as tyrosine kinase inhibitors, more particularly erbB inhibitors such as Herceptin. In addition, methods are disclosed for determining whether a potential drug is likely to produce a cardiotoxic effect. The methods involve analyzing lipid levels or the expression fatty acid oxidation enzymes, pAMP activated protein kinase, glucose uptake, to determine whether a fatty acid oxidation disorder is present. The identification of a fatty acid oxidation disorder can be used as a predictor of toxicity, especially cardiac toxicity, and as an indication that organ function should be carefully monitored if a drug such as a tyrosine kinase inhibitor is administered. Methods are also disclosed for protecting organs from metabolic stress and for the treatment of cells, such as adipocytes, to reduce their lipid content. | 2013-10-31 |
20130288286 | CELL OBSERVATION DEVICE AND CELL OBSERVATION METHOD - A cell observation device is provided with a reflection interference measurement light source | 2013-10-31 |
20130288287 | FIBROUS STRUCTURE - A fibrous structure comprising an assembly of hair follicle cells within a fibrous matrix. | 2013-10-31 |
20130288288 | ADAPTIVE CONTROL OF MICROBIAL POPULATIONS - The presently disclosed subject matter provides real-time adaptive manipulations of conditions in a bioreactor to optimize biochemical reactions occurring within the bioreactor. Optimization of a bioreactor does not need to be performed in small-scale, but real-time adaptive manipulations can occur in a bioreactor while the bioreactor is being used. | 2013-10-31 |
20130288289 | High Throughput Screen - The present invention relates to a structure comprising a biological membrane and a porous or perforated substrate, a biological membrane, a substrate, a high throughput screen, methods for production of the structure membrane and substrate, and a method for screening a large number of test compounds in a short period. More particularly it relates to a structure comprising a biological membrane adhered to a porous or perforated substrate, a biological membrane capable of adhering with high resistance seals to a substrate such as perforated glass and the ability to form sheets having predominantly an ion channel or transporter of interest, a high throughput screen for determining the effect of test compounds on ion channel or transporter activity, methods for manufacture of the structure, membrane and substrate, and a method for monitoring ion channel or transporter activity in a membrane. | 2013-10-31 |
20130288290 | SYSTEMS AND METHODS FOR MANIPULATION OF REGENERATIVE CELLSFROM ADIPOSE TISSUE - The invention provides methods for manipulating regenerative cells from adipose tissue. Specifically, it provides methods for enrichment of desired cells and enhancement of their therapeutic effects. | 2013-10-31 |
20130288291 | METHOD FOR COLLECTING A SAMPLE OF MICROORGANISMS FROM THE SURFACE OF A SOLID MATERIAL USING A CONTACTLESS PARTITIONING SYSTEM, AND APPARATUS FOR PARTITIONING THE SURFACE OF THE SOLID MATERIAL - The present invention relates to an apparatus for partitioning a sampling region on a solid surface and a method for collecting a microbial sample from a solid surface, in which an optimal sampling region is partitioned on a solid surface using a light source without bringing the solid surface into direct contact with a ruler or a partitioning tool. With the apparatus and method, a solid surface can be prevented from being contaminated during partitioning process, accuracy of sampling operation can be increased, partitioning operation can be continuously performed in a simple manner, and cost of sampling operation can be reduced. | 2013-10-31 |
20130288292 | SURFACE-TENSION BASED FLOW GUIDANCE IN A MICROSTRUCTURE ENVIRONMENT - This invention relates to a device and method for engineering microchannel geometries to take advantage of surface tension to guide fluid location. This technology may be used to construct compartmentalized systems of various materials that are added in liquid state, and may be used in a liquid state, or may be solidified, gelled, cross-linked, polymerized, or alternatively may be accumulated through gravity (e.g. cell settling), or centrifugation. | 2013-10-31 |